{ | |
"significant_genes": { | |
"Variable": [ | |
"ATG5", | |
"BATF3", | |
"BCL2L11", | |
"C1R", | |
"C4BPA", | |
"B3GAT1", | |
"BTK", | |
"BCAP31", | |
"CD40LG", | |
"C1QB", | |
"APP", | |
"DEFB4A", | |
"CXCR3", | |
"CCL8", | |
"HLA-DQA1", | |
"EBI3", | |
"IRAK2", | |
"LILRB5", | |
"BCL2", | |
"MAPK14", | |
"C3", | |
"ADGRE2", | |
"FADD", | |
"CD59", | |
"BATF", | |
"CCL15", | |
"TLR3", | |
"TP53", | |
"EGR2", | |
"HRAS", | |
"IL1R1", | |
"CD9", | |
"CIITA", | |
"HFE", | |
"FKBP5", | |
"DEFB103A", | |
"CD86", | |
"PTGS2", | |
"LTB4R", | |
"BST2", | |
"CR2", | |
"CD53", | |
"CXCR2", | |
"CCL20", | |
"FYN", | |
"PSMB5", | |
"CCND3", | |
"CTNNB1", | |
"CARD9", | |
"PTAFR", | |
"CCL3", | |
"ATG16L1", | |
"IL4R", | |
"S1PR1", | |
"DEFB103B", | |
"IL7", | |
"SLC2A1", | |
"BCL3", | |
"MBP", | |
"NFATC2", | |
"CCR8", | |
"POLR1G", | |
"FCAR", | |
"IKZF1", | |
"KLRC3", | |
"CCL5", | |
"CRADD", | |
"NT5E", | |
"ATG12", | |
"FAS", | |
"MALT1", | |
"CCRL2", | |
"CD14", | |
"MAPKAPK2", | |
"CCL22", | |
"CFH", | |
"IGF2R", | |
"IRGM", | |
"AIRE", | |
"LTB4R2", | |
"IL17A", | |
"FN1", | |
"TNFSF11", | |
"CFI", | |
"CXCL11", | |
"IL6", | |
"IRF7", | |
"CCL13", | |
"CD46", | |
"CD79B", | |
"ABL1", | |
"FOXP3", | |
"CD160", | |
"CD80", | |
"KLRA1P", | |
"CD19", | |
"LCP2", | |
"HLA-DRB3", | |
"NOTCH2", | |
"ITGA5", | |
"PSMC2", | |
"FCER1A", | |
"SPP1", | |
"DEFB1", | |
"RAG2", | |
"CCL2", | |
"IL22", | |
"MUC1", | |
"ACKR4", | |
"CD36", | |
"FCGR2B", | |
"SELE", | |
"CFD", | |
"ATG10", | |
"LIF", | |
"CCL19", | |
"NOD2", | |
"MAP4K4", | |
"IL13RA1", | |
"SELPLG", | |
"PDCD1", | |
"IL1RAP", | |
"ZBTB16", | |
"NLRP3", | |
"MX1", | |
"EGR1", | |
"CFB", | |
"ATG7", | |
"IL10", | |
"GZMK", | |
"IL32", | |
"CD1D", | |
"IL4", | |
"EDNRB", | |
"IL16", | |
"BLNK", | |
"IL21R", | |
"IL21", | |
"BCL10", | |
"TNFSF15", | |
"CD7", | |
"IL1B", | |
"IFI16", | |
"IL26", | |
"CD4", | |
"PDCD2", | |
"CUL9", | |
"SLAMF6", | |
"STAT4", | |
"ITLN2", | |
"GP1BB", | |
"BTLA", | |
"POU2F2", | |
"ITGA2B", | |
"MSR1", | |
"IL1RN", | |
"TIRAP", | |
"AICDA", | |
"TLR4", | |
"CLEC5A", | |
"CSF2", | |
"IL7R", | |
"TCF7", | |
"CD48", | |
"TNFSF8", | |
"ITGB1", | |
"CCL16", | |
"IL3", | |
"CD274", | |
"TNFSF13B", | |
"ITGA4", | |
"KLRG1", | |
"SLAMF1", | |
"IRF5", | |
"KCNJ2", | |
"IL2RA", | |
"CCR6", | |
"TOLLIP", | |
"TGFBI", | |
"CXCL1", | |
"CXCL8", | |
"TNFRSF17", | |
"CCR1", | |
"IRF3", | |
"CLEC6A", | |
"CX3CR1", | |
"CD1A", | |
"RAG1", | |
"CCR2", | |
"PDCD1LG2", | |
"CLU", | |
"IFI35", | |
"HLA-DMB", | |
"BAX", | |
"IRAK1", | |
"HLA-C", | |
"MME", | |
"CD70", | |
"PRKCD", | |
"NCAM1", | |
"IRAK4", | |
"CASP8", | |
"MAPK11", | |
"TAPBP", | |
"TNFRSF10C", | |
"CCR10", | |
"LCK", | |
"PAX5", | |
"MIF", | |
"CD58", | |
"CD164", | |
"TAGAP", | |
"IFNA2", | |
"CD163", | |
"CTSC", | |
"IRF4", | |
"CCL4", | |
"TRAF1", | |
"HAVCR2", | |
"CXCR6", | |
"IL12B", | |
"IL6R", | |
"CASP10", | |
"UBE2L3", | |
"C5", | |
"PTPN2", | |
"CD8B", | |
"MS4A1", | |
"TLR1", | |
"IL15", | |
"ENTPD1", | |
"KLRG2", | |
"CD96", | |
"PSMB7", | |
"CLEC4E", | |
"IKBKE", | |
"CCL26", | |
"B2M", | |
"CDKN1A", | |
"MYD88", | |
"TCF4", | |
"ITGAL", | |
"IL10RA", | |
"IL2RG", | |
"ITGB2", | |
"PLA2G2E", | |
"ICAM3", | |
"TRAF4", | |
"STAT1", | |
"C1QA", | |
"ICAM1", | |
"IFNL1", | |
"CD8A", | |
"BST1", | |
"TLR9", | |
"PML", | |
"CXCL12", | |
"CEACAM6", | |
"TNFSF12", | |
"IFNAR1", | |
"CD99", | |
"NFATC1", | |
"STAT3", | |
"IFIH1", | |
"HLA-DPA1", | |
"TLR2", | |
"ARHGDIB", | |
"PLAU", | |
"CCL23", | |
"ADA", | |
"CSF2RB", | |
"CD28", | |
"MRC1", | |
"RELB", | |
"CXCL2", | |
"IL6ST", | |
"CSF1", | |
"PDGFB", | |
"KLRB1", | |
"CD74", | |
"CD276", | |
"PTGER4", | |
"TNFRSF9", | |
"XCL1", | |
"C6", | |
"SYK", | |
"STAT5A", | |
"ITGAM", | |
"IL17F", | |
"TGFBR1", | |
"IFNB1", | |
"SMAD5", | |
"VCAM1", | |
"C7", | |
"IL27", | |
"CD81", | |
"IL2RB", | |
"CD34", | |
"GATA3", | |
"TLR5", | |
"IKBKB", | |
"KLRC1", | |
"IL20", | |
"KIR3DL1", | |
"IL11RA", | |
"PRDM1", | |
"NFKBIZ", | |
"CEBPB", | |
"NOTCH1", | |
"HAMP", | |
"S100A8", | |
"CD40", | |
"HLA-A", | |
"CR1", | |
"LILRB2", | |
"PSMD7", | |
"CD83", | |
"PLAUR", | |
"C1QBP", | |
"CD2", | |
"C1S", | |
"RTRAF", | |
"ELP1", | |
"CD55", | |
"TLR8", | |
"FCGR2A", | |
"TNFRSF1B", | |
"CX3CL1", | |
"CD3D", | |
"LAIR1", | |
"PDGFRB", | |
"CCR5", | |
"TRAF6", | |
"LITAF", | |
"XCR1", | |
"NCF4", | |
"THY1", | |
"FCGRT", | |
"IRAK3", | |
"IL5", | |
"CASP2", | |
"BCL6", | |
"MR1", | |
"IL23R", | |
"TNFRSF11A", | |
"CCL11", | |
"JAK3", | |
"KIT", | |
"KLRF1", | |
"MAF", | |
"PRF1", | |
"ICOS", | |
"SOCS3", | |
"SERPING1", | |
"ARG1", | |
"IL1RL2", | |
"GBP5", | |
"CCL18", | |
"GBP1", | |
"ABCB1", | |
"TGFBR2", | |
"NOD1", | |
"TBK1", | |
"IL18", | |
"LILRA1", | |
"LAG3", | |
"TFRC", | |
"HLA-DPB1", | |
"LTA", | |
"CD6", | |
"TNFSF4", | |
"BID", | |
"LILRA6", | |
"NFKB2", | |
"HLA-DOB", | |
"C9", | |
"ITGA6", | |
"ITGAE", | |
"CXCL13", | |
"ARG2", | |
"STAT6", | |
"GPI", | |
"CMKLR1", | |
"CCL7", | |
"NOS2", | |
"IFNL2", | |
"LILRB1", | |
"IL12A", | |
"LAMP3", | |
"KIR3DL3", | |
"TYK2", | |
"AHR", | |
"LY96", | |
"CEACAM8", | |
"IKZF3", | |
"MAPK1", | |
"ICAM5", | |
"IFNGR1", | |
"CSF3R", | |
"CYBB", | |
"IFIT2", | |
"TNFRSF13B", | |
"ICOSLG", | |
"HLA-B", | |
"ATM", | |
"CHUK", | |
"CD24", | |
"CD82", | |
"TNFRSF8", | |
"PSMB9", | |
"IRF8", | |
"IKZF2", | |
"IL9", | |
"CLEC7A", | |
"CD79A", | |
"CD247", | |
"TNF", | |
"RUNX1", | |
"CDH5", | |
"CD244", | |
"TAP2", | |
"DUSP4", | |
"SOCS1", | |
"MASP2", | |
"IL18RAP", | |
"ILF3", | |
"PLAAT4", | |
"LGALS3", | |
"CD5", | |
"PTPN6", | |
"PIGR", | |
"TIGIT", | |
"IRF1", | |
"GZMB", | |
"HLA-DRB1", | |
"NCR1", | |
"IL13", | |
"IL18R1", | |
"HLA-DMA", | |
"RAF1", | |
"LTF", | |
"CD27", | |
"PTPN22", | |
"PTK2", | |
"IDO1", | |
"TNFRSF14", | |
"LEF1", | |
"RORC", | |
"HLA-DQB1", | |
"CFP", | |
"LTBR", | |
"SLAMF7", | |
"PPARG", | |
"JAK1", | |
"MASP1", | |
"STAT5B", | |
"CD44", | |
"ITGAX", | |
"LILRA3", | |
"XBP1", | |
"CSF1R", | |
"TNFSF10", | |
"GNLY", | |
"CXCL10", | |
"KLRC2", | |
"LILRA2", | |
"IL19", | |
"TRAF3", | |
"HLA-DRA", | |
"IL1A", | |
"CASP3", | |
"LILRB3", | |
"KLRC4", | |
"IL1R2", | |
"ICAM4", | |
"TRAF2", | |
"LILRA5", | |
"CLEC4A", | |
"MBL2", | |
"TAP1", | |
"IFITM1", | |
"CISH", | |
"ZEB1", | |
"GFI1", | |
"CASP1", | |
"ICAM2", | |
"SRC", | |
"KIR3DL2", | |
"CXCR4", | |
"TAL1", | |
"NFATC3", | |
"SH2D1A", | |
"TICAM1", | |
"VTN", | |
"DPP4", | |
"KLRD1", | |
"CD3E", | |
"CTSG", | |
"MARCO", | |
"IL12RB1", | |
"RELA", | |
"JAK2", | |
"PLA2G2A", | |
"C2", | |
"CTSS", | |
"IL17B", | |
"CEACAM1", | |
"PPBP", | |
"CD22", | |
"C8A", | |
"ITLN1", | |
"FCER1G", | |
"CD209", | |
"KLRK1", | |
"MCL1", | |
"GZMA", | |
"MAP4K1", | |
"NFKBIA", | |
"NFIL3", | |
"SELL", | |
"IFNG", | |
"S100A9", | |
"CCL24", | |
"SMAD3", | |
"LILRB4", | |
"LILRA4", | |
"TNFAIP6", | |
"STAT2", | |
"MAP4K2", | |
"TNFAIP3", | |
"TGFB1", | |
"IKBKG", | |
"IL22RA2", | |
"IL23A", | |
"NFKB1", | |
"CCR7", | |
"C8B", | |
"PSMB8", | |
"PSMB10", | |
"ZAP70", | |
"PECAM1", | |
"CXCR1", | |
"PYCARD", | |
"SKI", | |
"TLR7", | |
"CXCL9", | |
"GPR183", | |
"ETS1", | |
"TNFRSF13C", | |
"TRAF5", | |
"SIGIRR", | |
"STING1", | |
"KLRF2", | |
"EOMES", | |
"C8G", | |
"IL1RL1", | |
"IL2", | |
"IFNAR2", | |
"CAMP", | |
"TBX21", | |
"TNFRSF4" | |
], | |
"Coefficient": [ | |
0.12078878420611808, | |
-0.08854174783252589, | |
0.07984523580515827, | |
0.07536325488871495, | |
-0.07533554582280953, | |
0.07478998924093884, | |
-0.073490939319399, | |
0.07309009172001353, | |
0.06943982514168305, | |
0.06903633572334215, | |
0.06896875433821881, | |
-0.06778293305290287, | |
0.06542158409837674, | |
-0.06481623520742012, | |
0.06370473762684915, | |
0.0635447386898998, | |
-0.06270529256546122, | |
-0.06060173811654362, | |
0.06031000471187429, | |
-0.0589690970668991, | |
0.05895111030515425, | |
-0.05831389463896789, | |
-0.05716306355988925, | |
-0.05695941686551145, | |
0.05694043105908112, | |
0.05675976765081241, | |
0.05627813865166633, | |
-0.05611251605919127, | |
-0.054675477940820484, | |
0.05461078777138128, | |
0.05411193849995958, | |
-0.05399192304396533, | |
0.05380461447672966, | |
-0.05372616343730029, | |
-0.0526174562533692, | |
0.052036528411438396, | |
-0.05181013330659103, | |
0.051795508178270167, | |
0.05121045175848623, | |
0.05035249706768742, | |
0.04942511702432582, | |
0.0493932041068017, | |
0.04937869577996659, | |
-0.04869554405585278, | |
0.04707150845946297, | |
0.046664964096919885, | |
0.04640932378024821, | |
-0.045569556282941064, | |
-0.04547486143159618, | |
0.04504953098012509, | |
-0.044837672294680865, | |
-0.04457835803431705, | |
0.0441880099129539, | |
-0.044034146473380754, | |
0.04370821137608709, | |
-0.043704823561937826, | |
0.043501857081307646, | |
-0.04345485256419683, | |
-0.04310814964462308, | |
-0.04287902225963604, | |
0.04272278330667157, | |
0.042709587023470594, | |
-0.04246993502592965, | |
-0.0423686090178879, | |
0.04215567785456602, | |
0.04176762151818441, | |
-0.04175060763440037, | |
0.039242306850764706, | |
0.038688483650033745, | |
0.03863051631304539, | |
-0.03845191001552302, | |
0.03816291336748062, | |
0.03796351510116932, | |
0.037935370082856044, | |
0.03789967320388176, | |
0.03770538214131235, | |
-0.03767026799436275, | |
0.03758109208171005, | |
-0.03755404694806122, | |
0.03754138446009454, | |
-0.037306557181639964, | |
0.03714566057603022, | |
-0.03712672538447346, | |
0.03708566152107113, | |
-0.036956250772477064, | |
0.03680316830735207, | |
0.03671998506643176, | |
-0.03650332276305435, | |
-0.03626174087786661, | |
-0.03619918198367009, | |
-0.036035751498292176, | |
-0.035768095170846254, | |
0.03560256077317447, | |
-0.03550755522804804, | |
0.03545851054791078, | |
0.03478791403065226, | |
-0.034710166700544866, | |
-0.03436609676061947, | |
0.03415274234435027, | |
0.03387137627011205, | |
-0.033820250841748466, | |
-0.03372419022913927, | |
0.03361219727749665, | |
-0.033544979865412126, | |
-0.033457871823278224, | |
0.03345424317640946, | |
0.03310094582286439, | |
-0.032660881482417435, | |
0.0325660661665476, | |
-0.03247428469469435, | |
-0.0324628978942046, | |
-0.03225160731020823, | |
0.032251009418357734, | |
0.0317594558845324, | |
0.03172521030707905, | |
0.031543503440952546, | |
-0.03152317080469783, | |
0.03132595199587188, | |
0.031045726855211245, | |
0.030790834749771047, | |
0.0307658246161527, | |
-0.03070893251246233, | |
-0.03049006266863516, | |
-0.030442914965425973, | |
0.030190819205120668, | |
0.02989494779796948, | |
-0.029328200448501957, | |
0.02902225119864648, | |
-0.029012236058497835, | |
-0.02875757467998398, | |
0.028670626365874623, | |
0.028653331814962768, | |
0.028531218847854836, | |
0.028520559427508693, | |
0.028405131643004934, | |
0.028362795627418166, | |
0.02822438280480986, | |
-0.028060777429564664, | |
-0.027896820480508806, | |
0.027835919576131844, | |
-0.027146611806101836, | |
-0.026827886206343708, | |
0.026824002667812284, | |
-0.026708911008395553, | |
-0.02668841222889182, | |
-0.02657420167115003, | |
0.0265109000572669, | |
0.026472570891086112, | |
-0.026456395071077266, | |
-0.026391140092642762, | |
-0.026204053284967586, | |
-0.026090966496738945, | |
-0.026054085524523013, | |
0.025982391162683274, | |
-0.025867741596604592, | |
0.025839323024880633, | |
-0.025782213709159944, | |
-0.025695961338019175, | |
-0.02568607938155082, | |
-0.025684392036078755, | |
0.02557243100362822, | |
-0.025530897747265184, | |
0.025521113631331627, | |
-0.02547485254972581, | |
0.0251315056531075, | |
0.02501583418864189, | |
-0.024884085071082102, | |
-0.02483294897344106, | |
-0.024703154791080095, | |
-0.024599289571570877, | |
-0.024422268335358786, | |
-0.02434502774587677, | |
0.024332525279485866, | |
-0.024312329194338324, | |
-0.024281214337834818, | |
-0.024258038476806142, | |
-0.024248160627325002, | |
0.024226800198734393, | |
0.024189855870950107, | |
0.02395722593078387, | |
0.023841529526871436, | |
0.02373600571973677, | |
0.023696317465220575, | |
0.02369434293280667, | |
-0.023588005856286363, | |
-0.02345711654246653, | |
-0.023455889376026065, | |
0.02338728889420174, | |
-0.023327621725562197, | |
0.023322152800275713, | |
-0.023166287233603478, | |
0.022860249729051433, | |
0.02260095314708186, | |
0.022574480538903964, | |
0.022565650726912273, | |
-0.022503951671740775, | |
-0.022502538304596302, | |
0.022493202566430465, | |
-0.022450543898858668, | |
-0.02241838316498987, | |
-0.02240799158511415, | |
0.022401785350300372, | |
0.02236716961488863, | |
0.02229700441124566, | |
-0.022241819384070834, | |
-0.022227234624665075, | |
0.02217752777511836, | |
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"Absolute Coefficient": [ | |
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}, | |
"cv_performance": { | |
"prediction": { | |
"accuracy": 61.73913043478261, | |
"precision": 35.98701298701299, | |
"recall": 44.0, | |
"f1": 38.803706097823735 | |
}, | |
"selection": { | |
"precision": 9.44741532976827, | |
"recall": 100.0, | |
"f1": 17.263843648208468, | |
"jaccard": 9.44741532976827 | |
} | |
} | |
} |