| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BCL2L11", | |
| "BATF3", | |
| "BCAP31", | |
| "APP", | |
| "BTK", | |
| "C1R", | |
| "B3GAT1", | |
| "C1QB", | |
| "CD40LG", | |
| "DEFB4A", | |
| "C4BPA", | |
| "HLA-DQA1", | |
| "CXCR3", | |
| "CCL8", | |
| "IRAK2", | |
| "ADGRE2", | |
| "EBI3", | |
| "C3", | |
| "MAPK14", | |
| "BCL2", | |
| "TLR3", | |
| "LILRB5", | |
| "CD9", | |
| "IL1R1", | |
| "EGR2", | |
| "DEFB103A", | |
| "TP53", | |
| "CD59", | |
| "HRAS", | |
| "CCL15", | |
| "BST2", | |
| "HFE", | |
| "BATF", | |
| "CIITA", | |
| "CXCR2", | |
| "CTNNB1", | |
| "FKBP5", | |
| "LTB4R", | |
| "CR2", | |
| "PTGS2", | |
| "CCND3", | |
| "CD86", | |
| "CD53", | |
| "CRADD", | |
| "CCL3", | |
| "FADD", | |
| "CARD9", | |
| "ATG16L1", | |
| "FYN", | |
| "PSMB5", | |
| "PTAFR", | |
| "IL4R", | |
| "NFATC2", | |
| "CD160", | |
| "CCL5", | |
| "S1PR1", | |
| "IL7", | |
| "CCR8", | |
| "MBP", | |
| "FOXP3", | |
| "CCL20", | |
| "POLR1G", | |
| "SLC2A1", | |
| "IKZF1", | |
| "MALT1", | |
| "FCAR", | |
| "IGF2R", | |
| "KLRC3", | |
| "CD80", | |
| "DEFB103B", | |
| "BCL3", | |
| "IRGM", | |
| "CCL22", | |
| "CCL2", | |
| "CD14", | |
| "ACKR4", | |
| "NT5E", | |
| "TNFSF11", | |
| "FN1", | |
| "MAPKAPK2", | |
| "CFH", | |
| "IL6", | |
| "CCL13", | |
| "IRF7", | |
| "IL17A", | |
| "CFI", | |
| "KLRA1P", | |
| "CD46", | |
| "CFD", | |
| "ATG12", | |
| "LTB4R2", | |
| "HLA-DRB3", | |
| "CD19", | |
| "LCP2", | |
| "CD79B", | |
| "CXCL11", | |
| "ATG10", | |
| "CCRL2", | |
| "EGR1", | |
| "NLRP3", | |
| "MUC1", | |
| "IL1RAP", | |
| "MAP4K4", | |
| "ITGA5", | |
| "CCL19", | |
| "NOTCH2", | |
| "RAG2", | |
| "IL13RA1", | |
| "CUL9", | |
| "PSMC2", | |
| "FCGR2B", | |
| "GZMK", | |
| "SELPLG", | |
| "IL21", | |
| "GP1BB", | |
| "CD1D", | |
| "FCER1A", | |
| "DEFB1", | |
| "AIRE", | |
| "CD36", | |
| "IL10", | |
| "PDCD1", | |
| "SPP1", | |
| "NOD2", | |
| "IFI16", | |
| "B2M", | |
| "IL22", | |
| "FAS", | |
| "KCNJ2", | |
| "MX1", | |
| "EDNRB", | |
| "BTLA", | |
| "ZBTB16", | |
| "IL16", | |
| "IL4", | |
| "PDCD1LG2", | |
| "TLR4", | |
| "BCL10", | |
| "LIF", | |
| "TNFSF15", | |
| "PDCD2", | |
| "SELE", | |
| "CD48", | |
| "STAT4", | |
| "CD7", | |
| "IL32", | |
| "TCF7", | |
| "IL7R", | |
| "ATG7", | |
| "C5", | |
| "CX3CR1", | |
| "CXCL1", | |
| "CLEC6A", | |
| "IL21R", | |
| "POU2F2", | |
| "IL2RA", | |
| "CSF2", | |
| "CASP10", | |
| "TNFSF13B", | |
| "ITLN2", | |
| "SLAMF6", | |
| "IL1RN", | |
| "MAPK11", | |
| "TOLLIP", | |
| "ITGB1", | |
| "TIRAP", | |
| "IL1B", | |
| "MSR1", | |
| "CD1A", | |
| "CXCL8", | |
| "KLRG1", | |
| "CFB", | |
| "CLU", | |
| "CLEC5A", | |
| "CD164", | |
| "TNFSF8", | |
| "SLAMF1", | |
| "CCL4", | |
| "IRF5", | |
| "MS4A1", | |
| "TGFBI", | |
| "TNFRSF17", | |
| "AICDA", | |
| "CD4", | |
| "CCR1", | |
| "TRAF1", | |
| "PAX5", | |
| "IL26", | |
| "IL3", | |
| "ITGA2B", | |
| "IRF3", | |
| "CD163", | |
| "CCR10", | |
| "PTPN2", | |
| "CD70", | |
| "CD274", | |
| "IRAK1", | |
| "IFI35", | |
| "ENTPD1", | |
| "CSF2RB", | |
| "TAGAP", | |
| "CD96", | |
| "RAG1", | |
| "TNFRSF10C", | |
| "TAPBP", | |
| "IL15", | |
| "ABL1", | |
| "CXCR6", | |
| "TLR9", | |
| "PRKCD", | |
| "IRF4", | |
| "CCL16", | |
| "LCK", | |
| "KIT", | |
| "CD8B", | |
| "CCR6", | |
| "MME", | |
| "CCL26", | |
| "BAX", | |
| "BLNK", | |
| "IL12B", | |
| "NCAM1", | |
| "IFNL1", | |
| "CTSC", | |
| "IL10RA", | |
| "IFNA2", | |
| "CCR2", | |
| "NFATC1", | |
| "ITGA4", | |
| "ARHGDIB", | |
| "TLR1", | |
| "CCL23", | |
| "ICAM3", | |
| "HLA-DMB", | |
| "CASP8", | |
| "TCF4", | |
| "STAT3", | |
| "ADA", | |
| "C1QA", | |
| "MYD88", | |
| "ITGB2", | |
| "KLRG2", | |
| "UBE2L3", | |
| "CD74", | |
| "IL2RG", | |
| "CD58", | |
| "CD276", | |
| "CD81", | |
| "IRAK4", | |
| "CDKN1A", | |
| "BID", | |
| "CD99", | |
| "STAT1", | |
| "PSMB7", | |
| "MRC1", | |
| "CD28", | |
| "CXCL2", | |
| "HLA-DPA1", | |
| "ATM", | |
| "TLR2", | |
| "MIF", | |
| "HLA-C", | |
| "TRAF4", | |
| "CLEC4E", | |
| "IKBKE", | |
| "IL6R", | |
| "HAVCR2", | |
| "PML", | |
| "CXCL12", | |
| "CSF1", | |
| "TLR8", | |
| "ICAM1", | |
| "PDGFB", | |
| "ITGAM", | |
| "TNFSF12", | |
| "SYK", | |
| "C6", | |
| "PLA2G2E", | |
| "RELB", | |
| "PTGER4", | |
| "KLRB1", | |
| "IFNAR1", | |
| "IFNB1", | |
| "CD34", | |
| "CD8A", | |
| "TGFBR1", | |
| "NOTCH1", | |
| "IFIT2", | |
| "TNFRSF9", | |
| "ARG2", | |
| "XCL1", | |
| "HAMP", | |
| "LILRB2", | |
| "C7", | |
| "CD40", | |
| "IL27", | |
| "LAIR1", | |
| "PSMD7", | |
| "STAT5A", | |
| "IL20", | |
| "LAG3", | |
| "LTA", | |
| "S100A8", | |
| "CD2", | |
| "NOD1", | |
| "CCL18", | |
| "GBP1", | |
| "NCF4", | |
| "PDGFRB", | |
| "GATA3", | |
| "FCGR2A", | |
| "ITGAL", | |
| "IL1RL2", | |
| "IL18", | |
| "IL2RB", | |
| "SERPING1", | |
| "TLR5", | |
| "CEACAM6", | |
| "IFIH1", | |
| "ARG1", | |
| "KIR3DL1", | |
| "HLA-A", | |
| "TRAF6", | |
| "CX3CL1", | |
| "PLAUR", | |
| "IKBKB", | |
| "GBP5", | |
| "CYBB", | |
| "KLRC1", | |
| "MAF", | |
| "CEBPB", | |
| "ITGA6", | |
| "NFKBIZ", | |
| "IL11RA", | |
| "IL6ST", | |
| "CMKLR1", | |
| "CLEC7A", | |
| "CHUK", | |
| "PRF1", | |
| "BST1", | |
| "PLAU", | |
| "NFKB2", | |
| "C1QBP", | |
| "VCAM1", | |
| "IL5", | |
| "HLA-B", | |
| "CCR5", | |
| "LITAF", | |
| "KLRF1", | |
| "CR1", | |
| "SMAD5", | |
| "CASP2", | |
| "CSF3R", | |
| "STAT6", | |
| "LILRB1", | |
| "ICOSLG", | |
| "CD3D", | |
| "PRDM1", | |
| "IL12A", | |
| "CCL11", | |
| "TNFRSF1B", | |
| "TFRC", | |
| "THY1", | |
| "RTRAF", | |
| "TGFBR2", | |
| "CD83", | |
| "IFNGR1", | |
| "KIR3DL3", | |
| "TBK1", | |
| "LILRA6", | |
| "TNFSF4", | |
| "HLA-DPB1", | |
| "XCR1", | |
| "CFP", | |
| "TYK2", | |
| "ITGAE", | |
| "IFNL2", | |
| "CEACAM8", | |
| "LY96", | |
| "GPI", | |
| "ICOS", | |
| "CD6", | |
| "JAK3", | |
| "LILRA3", | |
| "LAMP3", | |
| "CD55", | |
| "SOCS3", | |
| "CXCL13", | |
| "IL17F", | |
| "C9", | |
| "PSMB9", | |
| "FCGRT", | |
| "C1S", | |
| "IRAK3", | |
| "SOCS1", | |
| "IL18RAP", | |
| "GNLY", | |
| "TNFRSF13B", | |
| "CD27", | |
| "PTPN6", | |
| "CD244", | |
| "TNFRSF8", | |
| "PIGR", | |
| "IKZF3", | |
| "IL18R1", | |
| "HLA-DOB", | |
| "LILRA1", | |
| "IKZF2", | |
| "CD247", | |
| "TNF", | |
| "CDH5", | |
| "IL23R", | |
| "TNFRSF11A", | |
| "RORC", | |
| "LGALS3", | |
| "ELP1", | |
| "ILF3", | |
| "LEF1", | |
| "NOS2", | |
| "AHR", | |
| "PLAAT4", | |
| "BCL6", | |
| "DUSP4", | |
| "LTF", | |
| "TNFRSF14", | |
| "CSF1R", | |
| "ICAM5", | |
| "PPARG", | |
| "IL9", | |
| "PTPN22", | |
| "IRF1", | |
| "MR1", | |
| "RUNX1", | |
| "TIGIT", | |
| "TAP2", | |
| "IRF8", | |
| "HLA-DMA", | |
| "HLA-DQB1", | |
| "MAPK1", | |
| "KLRF2", | |
| "GFI1", | |
| "LTBR", | |
| "STAT5B", | |
| "GZMB", | |
| "C2", | |
| "NCR1", | |
| "LILRB3", | |
| "CD44", | |
| "ZEB1", | |
| "CASP1", | |
| "MASP2", | |
| "MASP1", | |
| "IL2", | |
| "RAF1", | |
| "KLRC4", | |
| "ETS1", | |
| "KLRC2", | |
| "HLA-DRB1", | |
| "ITGAX", | |
| "CCL7", | |
| "XBP1", | |
| "TRAF3", | |
| "TAL1", | |
| "SLAMF7", | |
| "TNFSF10", | |
| "IL12RB1", | |
| "LILRA5", | |
| "TRAF2", | |
| "IL1RL1", | |
| "EOMES", | |
| "MARCO", | |
| "PTK2", | |
| "LILRA4", | |
| "ICAM2", | |
| "IFITM1", | |
| "CD5", | |
| "JAK1", | |
| "HLA-DRA", | |
| "IL13", | |
| "IFNAR2", | |
| "FCER1G", | |
| "CD82", | |
| "IDO1", | |
| "ITLN1", | |
| "PLA2G2A", | |
| "NFATC3", | |
| "LILRA2", | |
| "ICAM4", | |
| "CXCR1", | |
| "TLR7", | |
| "CTSS", | |
| "CLEC4A", | |
| "ZAP70", | |
| "CASP3", | |
| "MAP4K2", | |
| "CD3E", | |
| "CTSG", | |
| "MBL2", | |
| "CD209", | |
| "PSMB10", | |
| "TICAM1", | |
| "CD79A", | |
| "SH2D1A", | |
| "TAP1", | |
| "CXCL10", | |
| "IL1R2", | |
| "MCL1", | |
| "ABCB1", | |
| "CD22", | |
| "TNFRSF4", | |
| "CXCR4", | |
| "LILRB4", | |
| "S100A9", | |
| "JAK2", | |
| "GZMA", | |
| "SMAD3", | |
| "VTN", | |
| "TBX21", | |
| "PSMB8", | |
| "C8A", | |
| "PYCARD", | |
| "NFIL3", | |
| "PPBP", | |
| "SIGIRR", | |
| "SKI", | |
| "IL1A", | |
| "CXCL9", | |
| "IL19", | |
| "TRAF5", | |
| "TNFAIP6", | |
| "KLRD1", | |
| "CD24", | |
| "MAP4K1", | |
| "PECAM1", | |
| "SELL", | |
| "CISH", | |
| "CAMP", | |
| "NFKB1", | |
| "STING1", | |
| "CEACAM1", | |
| "RELA", | |
| "IL23A", | |
| "STAT2", | |
| "TGFB1", | |
| "IL22RA2", | |
| "CCL24", | |
| "TNFAIP3", | |
| "C8G", | |
| "CCR7", | |
| "IKBKG", | |
| "IFNG", | |
| "SRC", | |
| "NFKBIA", | |
| "TNFRSF13C", | |
| "DPP4", | |
| "KIR3DL2", | |
| "KLRK1", | |
| "C8B", | |
| "IL17B", | |
| "GPR183" | |
| ], | |
| "Coefficient": [ | |
| 0.11798413120969642, | |
| 0.08666130393051363, | |
| -0.077641662045019, | |
| 0.07409601383070705, | |
| 0.07336457367158232, | |
| -0.07315728373567759, | |
| 0.07097371948528682, | |
| 0.06872917143164825, | |
| 0.06834865385067065, | |
| 0.06777374621725027, | |
| -0.06758116406036407, | |
| -0.06659853671766439, | |
| 0.06542786235867633, | |
| 0.06512018154209785, | |
| -0.06499963338040558, | |
| -0.0621379575470394, | |
| -0.061110276541345834, | |
| 0.06012305717344473, | |
| 0.059757257773355534, | |
| -0.05952862723746733, | |
| 0.058624269957878054, | |
| 0.057688015353379335, | |
| -0.05756066222665973, | |
| -0.05753885894630961, | |
| 0.0565649862594328, | |
| -0.05576913777459645, | |
| 0.055718434266039146, | |
| -0.055590972357846574, | |
| -0.05516998562937534, | |
| 0.053068817747085946, | |
| 0.05305394190465987, | |
| 0.05294760115609438, | |
| -0.05247686146014164, | |
| 0.05230002788339596, | |
| 0.052106344266140886, | |
| 0.05180665522611455, | |
| -0.05175353130039958, | |
| -0.05138353713461042, | |
| 0.05138015308426852, | |
| 0.051248487926854124, | |
| 0.050617405531023285, | |
| 0.05009627665104563, | |
| -0.04986093935865141, | |
| 0.04981790530929959, | |
| -0.04874883389466025, | |
| -0.048444476721841774, | |
| -0.04804313502866216, | |
| -0.047891142096645335, | |
| -0.04579620828849513, | |
| 0.04570558339857941, | |
| 0.0456429404074772, | |
| 0.045436159057567566, | |
| 0.045409332560073415, | |
| -0.045287682537139, | |
| 0.04520589157118446, | |
| 0.0449785230694836, | |
| -0.04441729732523385, | |
| -0.04371323767811933, | |
| 0.04357987020633948, | |
| -0.04349759595623615, | |
| -0.04349687775683477, | |
| -0.0431388655479935, | |
| 0.04292639839973613, | |
| 0.04284912555779363, | |
| -0.04245143612049839, | |
| -0.0420521841800108, | |
| -0.041884043940977486, | |
| -0.04183119536773417, | |
| 0.04166164352310722, | |
| -0.04072895682901175, | |
| 0.040711354581443614, | |
| -0.0406283000676752, | |
| 0.040149987710277016, | |
| 0.03985391637926617, | |
| 0.0391876929202217, | |
| 0.03914010136733174, | |
| 0.03908831252492541, | |
| 0.03905943609733074, | |
| -0.03821393855976944, | |
| 0.038037147983849495, | |
| 0.0377687716257072, | |
| 0.03770195067097856, | |
| 0.03762231526605712, | |
| -0.037559022586656866, | |
| 0.037441392408342614, | |
| -0.03672945903732287, | |
| 0.03633109203577784, | |
| 0.03625927553224979, | |
| -0.03625517317868979, | |
| 0.03620312852730074, | |
| 0.03604753498989825, | |
| 0.035909623646233964, | |
| -0.035854844734905175, | |
| 0.03553169764536654, | |
| -0.03510496285988558, | |
| -0.035010699066006234, | |
| -0.03468150524647845, | |
| 0.03466025377586859, | |
| 0.034503722376342236, | |
| 0.034152715494258926, | |
| -0.03412522366856083, | |
| -0.03402264456805977, | |
| -0.03393757991409201, | |
| 0.03388467152179673, | |
| 0.03378744847798918, | |
| 0.0335541978359991, | |
| 0.033456443765605234, | |
| -0.033269443641945215, | |
| 0.033176428398429825, | |
| 0.03291818478429868, | |
| -0.032435751310141155, | |
| -0.0323168904309408, | |
| -0.0320476934024472, | |
| 0.03163765076349147, | |
| -0.031623542308501854, | |
| -0.03134276346339095, | |
| 0.03109599267267419, | |
| -0.031001645138635747, | |
| -0.030930404534157324, | |
| -0.03086591930726524, | |
| -0.03056509450898344, | |
| -0.030470774292230565, | |
| 0.03007292764307333, | |
| 0.0300067398530984, | |
| -0.02986799984033544, | |
| 0.02964178241174997, | |
| -0.02961873901194916, | |
| 0.029595675918017886, | |
| 0.02947568140682978, | |
| -0.029184456713186643, | |
| 0.02905617467324822, | |
| 0.029055788562767675, | |
| -0.028991754506877118, | |
| -0.028892053577513382, | |
| 0.028743901491463136, | |
| 0.028531357450974883, | |
| 0.028327001536404387, | |
| -0.028073292623347543, | |
| -0.028038624885001955, | |
| 0.02803401500307747, | |
| 0.027875590602824976, | |
| -0.027861539458274544, | |
| -0.027853207531577256, | |
| -0.02784722245068054, | |
| -0.027773760881960676, | |
| -0.027676456491784785, | |
| 0.027532269771686966, | |
| 0.027269046315396516, | |
| -0.02708057805283476, | |
| 0.027000999617555026, | |
| -0.026962870417730232, | |
| -0.026904906057682178, | |
| 0.026878104786983742, | |
| -0.026845923901878354, | |
| 0.02671209289270818, | |
| -0.02664066853401978, | |
| -0.026543139519547475, | |
| 0.026486231424763078, | |
| -0.026446064587722487, | |
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| ], | |
| "Absolute Coefficient": [ | |
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| ] | |
| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 60.8695652173913, | |
| "precision": 36.34415584415585, | |
| "recall": 46.666666666666664, | |
| "f1": 39.547511312217196 | |
| }, | |
| "selection": { | |
| "precision": 9.44741532976827, | |
| "recall": 100.0, | |
| "f1": 17.263843648208468, | |
| "jaccard": 9.44741532976827 | |
| } | |
| } | |
| } |