| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BATF3", | |
| "BCL2L11", | |
| "B3GAT1", | |
| "C1R", | |
| "BCAP31", | |
| "C4BPA", | |
| "BTK", | |
| "CD40LG", | |
| "C1QB", | |
| "CCL8", | |
| "APP", | |
| "CXCR3", | |
| "DEFB4A", | |
| "BCL2", | |
| "EBI3", | |
| "HLA-DQA1", | |
| "LILRB5", | |
| "IRAK2", | |
| "CCL15", | |
| "MAPK14", | |
| "CD59", | |
| "FADD", | |
| "C3", | |
| "HFE", | |
| "TP53", | |
| "TLR3", | |
| "BATF", | |
| "ADGRE2", | |
| "EGR2", | |
| "IL1R1", | |
| "HRAS", | |
| "CXCR2", | |
| "LTB4R", | |
| "CD9", | |
| "CD86", | |
| "DEFB103A", | |
| "FKBP5", | |
| "CD53", | |
| "PTGS2", | |
| "CCL20", | |
| "CIITA", | |
| "BST2", | |
| "CR2", | |
| "ATG16L1", | |
| "CCL3", | |
| "BCL3", | |
| "IL7", | |
| "PSMB5", | |
| "FYN", | |
| "PTAFR", | |
| "CARD9", | |
| "CTNNB1", | |
| "NFATC2", | |
| "CCR8", | |
| "DEFB103B", | |
| "CRADD", | |
| "IL4R", | |
| "S1PR1", | |
| "CCND3", | |
| "FCAR", | |
| "CCL5", | |
| "KLRC3", | |
| "IKZF1", | |
| "ACKR4", | |
| "IL17A", | |
| "MBP", | |
| "POLR1G", | |
| "NT5E", | |
| "CCL22", | |
| "FN1", | |
| "IL6", | |
| "CCL2", | |
| "CCRL2", | |
| "CD46", | |
| "IRGM", | |
| "FAS", | |
| "CD14", | |
| "AIRE", | |
| "MALT1", | |
| "CFI", | |
| "IRF7", | |
| "ABL1", | |
| "ATG7", | |
| "CCL13", | |
| "KLRA1P", | |
| "IGF2R", | |
| "MAPKAPK2", | |
| "FOXP3", | |
| "ATG10", | |
| "CD79B", | |
| "LTB4R2", | |
| "TNFSF11", | |
| "LCP2", | |
| "CD160", | |
| "SLC2A1", | |
| "CFH", | |
| "CD80", | |
| "ATG12", | |
| "CXCL11", | |
| "FCGR2B", | |
| "CD19", | |
| "NOTCH2", | |
| "MUC1", | |
| "HLA-DRB3", | |
| "CCL19", | |
| "PSMC2", | |
| "RAG2", | |
| "ITGA5", | |
| "DEFB1", | |
| "SPP1", | |
| "IL22", | |
| "FCER1A", | |
| "SELE", | |
| "CD36", | |
| "LIF", | |
| "IL10", | |
| "CFD", | |
| "NOD2", | |
| "PDCD1", | |
| "IL1RAP", | |
| "NLRP3", | |
| "MAP4K4", | |
| "SELPLG", | |
| "EGR1", | |
| "ZBTB16", | |
| "MX1", | |
| "IL16", | |
| "CD7", | |
| "IL4", | |
| "CD274", | |
| "BLNK", | |
| "EDNRB", | |
| "IL32", | |
| "IL13RA1", | |
| "CD1D", | |
| "CFB", | |
| "GZMK", | |
| "IFI16", | |
| "TNFSF15", | |
| "IL21R", | |
| "TIRAP", | |
| "CSF2", | |
| "IL1B", | |
| "IL26", | |
| "BAX", | |
| "CUL9", | |
| "BCL10", | |
| "CD4", | |
| "CCL16", | |
| "IL21", | |
| "GP1BB", | |
| "CCR1", | |
| "CLEC6A", | |
| "IL1RN", | |
| "TCF7", | |
| "TLR4", | |
| "TNFSF8", | |
| "PDCD2", | |
| "MSR1", | |
| "CD48", | |
| "IL7R", | |
| "SLAMF6", | |
| "POU2F2", | |
| "AICDA", | |
| "STAT4", | |
| "TNFRSF17", | |
| "CLEC5A", | |
| "ITGA4", | |
| "CD1A", | |
| "TNFSF13B", | |
| "ITLN2", | |
| "IRF3", | |
| "IL2RA", | |
| "CXCL8", | |
| "SLAMF1", | |
| "RAG1", | |
| "ITGA2B", | |
| "KCNJ2", | |
| "TGFBI", | |
| "CD70", | |
| "BTLA", | |
| "CCR2", | |
| "C5", | |
| "CLU", | |
| "ITGB1", | |
| "KLRG1", | |
| "TOLLIP", | |
| "TAPBP", | |
| "B2M", | |
| "IL3", | |
| "ADA", | |
| "IRF5", | |
| "CASP10", | |
| "IRAK1", | |
| "IFI35", | |
| "MAPK11", | |
| "HLA-DMB", | |
| "UBE2L3", | |
| "CD58", | |
| "MME", | |
| "LCK", | |
| "CCR6", | |
| "CD164", | |
| "CCL4", | |
| "CD163", | |
| "KLRG2", | |
| "TRAF1", | |
| "CCL26", | |
| "IFNA2", | |
| "PSMB7", | |
| "HAVCR2", | |
| "MIF", | |
| "PAX5", | |
| "PRKCD", | |
| "IRF4", | |
| "CTSC", | |
| "IL12B", | |
| "TLR1", | |
| "NCAM1", | |
| "PDCD1LG2", | |
| "IL6R", | |
| "TNFRSF10C", | |
| "CD8B", | |
| "PTPN2", | |
| "CXCL1", | |
| "TRAF4", | |
| "IRAK4", | |
| "ARHGDIB", | |
| "IL10RA", | |
| "CD96", | |
| "PML", | |
| "HLA-C", | |
| "CLEC4E", | |
| "CD28", | |
| "ICAM1", | |
| "TLR9", | |
| "CX3CR1", | |
| "CD34", | |
| "IFNL1", | |
| "CD276", | |
| "PLA2G2E", | |
| "CCR10", | |
| "ENTPD1", | |
| "CXCR6", | |
| "MYD88", | |
| "TAGAP", | |
| "IKBKE", | |
| "CCL23", | |
| "MS4A1", | |
| "ITGAL", | |
| "ITGB2", | |
| "CASP8", | |
| "CD99", | |
| "PDGFB", | |
| "IL2RG", | |
| "IL27", | |
| "TCF4", | |
| "CDKN1A", | |
| "CD8A", | |
| "IL15", | |
| "TNFSF12", | |
| "IFIH1", | |
| "BST1", | |
| "CXCL12", | |
| "KLRB1", | |
| "IL6ST", | |
| "CR1", | |
| "TLR2", | |
| "PLAU", | |
| "NFATC1", | |
| "C1QA", | |
| "STAT1", | |
| "KLRC1", | |
| "C6", | |
| "RELB", | |
| "STAT5A", | |
| "HLA-DPA1", | |
| "CSF1", | |
| "CXCL2", | |
| "IFNAR1", | |
| "ICAM3", | |
| "STAT3", | |
| "CSF2RB", | |
| "CEACAM6", | |
| "CD74", | |
| "TNFRSF9", | |
| "CCL11", | |
| "XCL1", | |
| "PTGER4", | |
| "IKBKB", | |
| "IFNB1", | |
| "NOTCH1", | |
| "CCR5", | |
| "TGFBR1", | |
| "MRC1", | |
| "BID", | |
| "SYK", | |
| "PRDM1", | |
| "LILRB2", | |
| "C1QBP", | |
| "ITGAM", | |
| "VCAM1", | |
| "CD81", | |
| "S100A8", | |
| "NFKBIZ", | |
| "IL17F", | |
| "SMAD5", | |
| "ARG1", | |
| "ELP1", | |
| "HAMP", | |
| "MR1", | |
| "TLR5", | |
| "C7", | |
| "LAIR1", | |
| "TRAF6", | |
| "CD3D", | |
| "TLR8", | |
| "CD40", | |
| "XCR1", | |
| "GATA3", | |
| "FCGRT", | |
| "IL18", | |
| "KIR3DL1", | |
| "MAF", | |
| "NOD1", | |
| "HLA-A", | |
| "PSMD7", | |
| "FCGR2A", | |
| "ARG2", | |
| "AHR", | |
| "PDGFRB", | |
| "IL2RB", | |
| "CD2", | |
| "BCL6", | |
| "RTRAF", | |
| "LAG3", | |
| "CCL18", | |
| "IL20", | |
| "IRAK3", | |
| "CD24", | |
| "IL5", | |
| "LITAF", | |
| "NFKB2", | |
| "PLAUR", | |
| "SOCS3", | |
| "CEBPB", | |
| "LTA", | |
| "TFRC", | |
| "TBK1", | |
| "C1S", | |
| "PRF1", | |
| "CD55", | |
| "GBP5", | |
| "TNFRSF13B", | |
| "IL23R", | |
| "SERPING1", | |
| "GPI", | |
| "HLA-DPB1", | |
| "THY1", | |
| "LILRA1", | |
| "NCF4", | |
| "KIT", | |
| "IL1RL2", | |
| "CASP2", | |
| "TNFRSF11A", | |
| "JAK3", | |
| "LY96", | |
| "TNFRSF1B", | |
| "TYK2", | |
| "KLRF1", | |
| "GBP1", | |
| "LILRB1", | |
| "ITGA6", | |
| "TNFSF4", | |
| "NOS2", | |
| "LILRA6", | |
| "IL12A", | |
| "STAT6", | |
| "ITGAE", | |
| "LAMP3", | |
| "ICOS", | |
| "IFNL2", | |
| "CD6", | |
| "CD83", | |
| "IL11RA", | |
| "HLA-DOB", | |
| "TGFBR2", | |
| "TAP2", | |
| "IFIT2", | |
| "CD27", | |
| "CHUK", | |
| "CD79A", | |
| "ABCB1", | |
| "PTPN6", | |
| "CX3CL1", | |
| "KIR3DL3", | |
| "CSF3R", | |
| "TNFRSF8", | |
| "CLEC7A", | |
| "HLA-DRB1", | |
| "MASP1", | |
| "PLAAT4", | |
| "ICOSLG", | |
| "TNF", | |
| "CMKLR1", | |
| "IL9", | |
| "CD247", | |
| "CXCL13", | |
| "CCL7", | |
| "ILF3", | |
| "C9", | |
| "PIGR", | |
| "PPARG", | |
| "TNFRSF14", | |
| "CYBB", | |
| "MAPK1", | |
| "IL18RAP", | |
| "CD5", | |
| "HLA-B", | |
| "HLA-DMA", | |
| "ICAM5", | |
| "SOCS1", | |
| "PTPN22", | |
| "PSMB9", | |
| "IKZF2", | |
| "RUNX1", | |
| "IRF8", | |
| "CEACAM8", | |
| "CD82", | |
| "TIGIT", | |
| "IKZF3", | |
| "NCR1", | |
| "LTF", | |
| "TRAF3", | |
| "XBP1", | |
| "DUSP4", | |
| "CD244", | |
| "LILRA3", | |
| "IFNGR1", | |
| "CEACAM1", | |
| "CD44", | |
| "IDO1", | |
| "CDH5", | |
| "HLA-DQB1", | |
| "MASP2", | |
| "SLAMF7", | |
| "LTBR", | |
| "LGALS3", | |
| "JAK1", | |
| "ZEB1", | |
| "CXCR1", | |
| "ICAM2", | |
| "ITGAX", | |
| "GZMB", | |
| "CASP3", | |
| "STAT5B", | |
| "LEF1", | |
| "RAF1", | |
| "LILRB3", | |
| "IL19", | |
| "KLRC4", | |
| "C8A", | |
| "IFNG", | |
| "CFP", | |
| "IRF1", | |
| "CISH", | |
| "RORC", | |
| "TICAM1", | |
| "TRAF2", | |
| "CD22", | |
| "HLA-DRA", | |
| "DPP4", | |
| "LILRA2", | |
| "IL1A", | |
| "PTK2", | |
| "TAL1", | |
| "CASP1", | |
| "TNFSF10", | |
| "CLEC4A", | |
| "CTSG", | |
| "IL1R2", | |
| "LILRA5", | |
| "IL13", | |
| "KLRD1", | |
| "VTN", | |
| "GZMA", | |
| "CSF1R", | |
| "NFATC3", | |
| "MBL2", | |
| "IL17B", | |
| "SRC", | |
| "KIR3DL2", | |
| "IL18R1", | |
| "NFIL3", | |
| "RELA", | |
| "ATM", | |
| "MAP4K1", | |
| "CXCR4", | |
| "C2", | |
| "ICAM4", | |
| "KLRC2", | |
| "TNFAIP6", | |
| "SKI", | |
| "C8G", | |
| "IL12RB1", | |
| "CCL24", | |
| "IFITM1", | |
| "PPBP", | |
| "KLRK1", | |
| "IL22RA2", | |
| "FCER1G", | |
| "GNLY", | |
| "C8B", | |
| "IL2", | |
| "MARCO", | |
| "GFI1", | |
| "SH2D1A", | |
| "IL23A", | |
| "TNFAIP3", | |
| "TAP1", | |
| "LILRB4", | |
| "EOMES", | |
| "CXCL10", | |
| "CTSS", | |
| "TRAF5", | |
| "S100A9", | |
| "MCL1", | |
| "JAK2", | |
| "CXCL9", | |
| "LILRA4", | |
| "TNFRSF13C", | |
| "SELL", | |
| "CCR7", | |
| "PSMB10", | |
| "SMAD3", | |
| "IFNAR2", | |
| "ITLN1", | |
| "NFKBIA", | |
| "CAMP", | |
| "CD3E", | |
| "STING1", | |
| "IKBKG", | |
| "PSMB8", | |
| "NFKB1", | |
| "PLA2G2A", | |
| "PECAM1", | |
| "CD209", | |
| "GPR183", | |
| "TLR7", | |
| "MAP4K2", | |
| "IL1RL1", | |
| "ETS1", | |
| "TNFRSF4", | |
| "TBX21", | |
| "ZAP70", | |
| "KLRF2", | |
| "TGFB1", | |
| "SIGIRR", | |
| "PYCARD", | |
| "STAT2" | |
| ], | |
| "Coefficient": [ | |
| 0.11788318963087428, | |
| -0.0868284798323133, | |
| 0.08068493769241065, | |
| 0.07683325041568768, | |
| 0.07579829387686546, | |
| 0.07513783797532571, | |
| -0.07183968396674802, | |
| -0.07145473856597649, | |
| 0.06915755328156363, | |
| 0.06826705619524157, | |
| -0.06726365520255086, | |
| 0.06639996506291701, | |
| 0.06509504387535361, | |
| -0.0642982134192648, | |
| 0.0639492195021737, | |
| 0.061842673042182085, | |
| 0.06180234355176287, | |
| -0.061570706927820844, | |
| -0.0607131563666952, | |
| 0.06008530010636142, | |
| -0.05992325778887338, | |
| -0.05903961767152301, | |
| -0.05882352007420981, | |
| 0.057150676807280885, | |
| -0.056791324813683854, | |
| -0.05562522869808358, | |
| 0.05532575315789723, | |
| 0.055251811268554836, | |
| -0.055002443680611815, | |
| -0.05473352313811196, | |
| 0.05450776695783569, | |
| 0.053266037540602405, | |
| 0.05305378374227811, | |
| 0.052701283022249544, | |
| -0.052437066188290256, | |
| -0.05187482861339485, | |
| 0.051585351013795265, | |
| -0.05079040020103434, | |
| 0.05063296973682061, | |
| 0.050519700321595466, | |
| -0.050437747761046196, | |
| 0.04940055205134223, | |
| 0.04891363676600713, | |
| 0.04859665481373109, | |
| -0.048183225421073284, | |
| -0.047856512137691334, | |
| -0.04713723052659344, | |
| -0.045540810456607274, | |
| 0.04537730116137013, | |
| 0.04537023097665308, | |
| 0.04502948179603571, | |
| -0.044775056056802244, | |
| -0.04466556521939594, | |
| -0.044453611707111394, | |
| 0.04435851711125366, | |
| 0.04435790086627612, | |
| -0.04362211924641441, | |
| 0.04337305585310507, | |
| -0.04295959339002668, | |
| 0.04279204138828694, | |
| -0.042692176278838374, | |
| 0.04253531219332673, | |
| 0.04234878092802984, | |
| -0.04098570021122157, | |
| 0.03943715424810518, | |
| -0.039416550002069, | |
| -0.039326352916369565, | |
| 0.03930438656709525, | |
| 0.03906020597715366, | |
| 0.03875387267262887, | |
| 0.03868840257074225, | |
| 0.03847722330836647, | |
| 0.03824756031776232, | |
| 0.03819293666407966, | |
| -0.03800331934228561, | |
| 0.037864080966911524, | |
| 0.03768977048612786, | |
| 0.03754803148504648, | |
| -0.037495018733168274, | |
| -0.037420659588128034, | |
| 0.037352796105034856, | |
| 0.037331429261448834, | |
| -0.03714277666503323, | |
| 0.036782493170588605, | |
| -0.036778404296374655, | |
| 0.03656499355938629, | |
| -0.036417535117717274, | |
| 0.03624099293115225, | |
| -0.03618213258397316, | |
| 0.035838181394526256, | |
| -0.0358336865772757, | |
| 0.035816072102992695, | |
| -0.035792682889592566, | |
| -0.03559849249771499, | |
| 0.03489344733475257, | |
| 0.034658587850605584, | |
| 0.03463721241029143, | |
| -0.0342843814286386, | |
| 0.034183233194558085, | |
| -0.03414138434552929, | |
| -0.033981390512313296, | |
| 0.03388338701805844, | |
| 0.03382944886887962, | |
| -0.033611851158370024, | |
| -0.033298515602862414, | |
| 0.03329555679952664, | |
| -0.03314642526934913, | |
| -0.03302617792428502, | |
| 0.032678273263786306, | |
| -0.032588087932633986, | |
| 0.03247788408702869, | |
| 0.03222991496126234, | |
| -0.03194785409872898, | |
| -0.03184530815342943, | |
| -0.03183313554116338, | |
| 0.03175129796348574, | |
| -0.03155671085108858, | |
| 0.03140996352809846, | |
| -0.03129448117798978, | |
| 0.031251130490870166, | |
| -0.031089006976963728, | |
| -0.031014661499396568, | |
| 0.030772803860484615, | |
| 0.03043059161251547, | |
| 0.03008207457684195, | |
| -0.030040509465603115, | |
| 0.029732301768031467, | |
| 0.02944814900400352, | |
| -0.029245903520655276, | |
| 0.029137325993473715, | |
| -0.02874536133063542, | |
| 0.028629599950384336, | |
| 0.028301914294755592, | |
| 0.028187695043971367, | |
| 0.02780759269560364, | |
| 0.027761968392263442, | |
| -0.02768067754005124, | |
| -0.02749777379783698, | |
| 0.027469226925121874, | |
| 0.027403151338367432, | |
| 0.027386971959207296, | |
| -0.02737451459354991, | |
| 0.02735654421622384, | |
| -0.027341834137429015, | |
| -0.027161246792656527, | |
| 0.027121106216020024, | |
| 0.02699461734633606, | |
| -0.026967734696661295, | |
| -0.026945657101333502, | |
| -0.02649993933988445, | |
| -0.026221903341022215, | |
| -0.026179619987609717, | |
| 0.026085741807781972, | |
| -0.02600095855218167, | |
| 0.02585525325994554, | |
| 0.025783069503040594, | |
| -0.025719313473764528, | |
| 0.025674741421674262, | |
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| -0.025639081005018088, | |
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| 3.554084696968478e-05, | |
| 3.3007790097918444e-05 | |
| ], | |
| "Absolute Coefficient": [ | |
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| ] | |
| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 61.73913043478261, | |
| "precision": 35.38095238095238, | |
| "recall": 40.666666666666664, | |
| "f1": 37.39194139194139 | |
| }, | |
| "selection": { | |
| "precision": 9.44741532976827, | |
| "recall": 100.0, | |
| "f1": 17.263843648208468, | |
| "jaccard": 9.44741532976827 | |
| } | |
| } | |
| } |