| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BCL2L11", | |
| "BATF3", | |
| "BCAP31", | |
| "ADGRE2", | |
| "BTK", | |
| "C1R", | |
| "B3GAT1", | |
| "C4BPA", | |
| "CD40LG", | |
| "C1QB", | |
| "CCL8", | |
| "CXCR3", | |
| "LILRB5", | |
| "DEFB4A", | |
| "HLA-DQA1", | |
| "MAPK14", | |
| "IRAK2", | |
| "EBI3", | |
| "BCL2", | |
| "CD86", | |
| "EGR2", | |
| "TLR3", | |
| "C3", | |
| "TP53", | |
| "BCL3", | |
| "CD9", | |
| "IL1R1", | |
| "HRAS", | |
| "HFE", | |
| "DEFB103A", | |
| "CCL15", | |
| "CARD9", | |
| "CCL3", | |
| "CD53", | |
| "LTB4R", | |
| "PTGS2", | |
| "CXCR2", | |
| "BST2", | |
| "FADD", | |
| "CIITA", | |
| "CCL20", | |
| "CR2", | |
| "CCND3", | |
| "CD59", | |
| "FKBP5", | |
| "SLC2A1", | |
| "FYN", | |
| "PSMB5", | |
| "PTAFR", | |
| "IL7", | |
| "MBP", | |
| "DEFB103B", | |
| "CCL5", | |
| "CTNNB1", | |
| "BATF", | |
| "IKZF1", | |
| "FCAR", | |
| "NFATC2", | |
| "IL4R", | |
| "APP", | |
| "CCR8", | |
| "CRADD", | |
| "KLRC3", | |
| "IL6", | |
| "CCRL2", | |
| "ATG7", | |
| "IGF2R", | |
| "S1PR1", | |
| "CD46", | |
| "CD160", | |
| "CCL22", | |
| "NT5E", | |
| "FOXP3", | |
| "POLR1G", | |
| "CCR6", | |
| "IL17A", | |
| "CD80", | |
| "FAS", | |
| "CFI", | |
| "IRF7", | |
| "TNFSF11", | |
| "CFH", | |
| "FN1", | |
| "MAPKAPK2", | |
| "IRGM", | |
| "ATG16L1", | |
| "MALT1", | |
| "RAG2", | |
| "LTB4R2", | |
| "CCL19", | |
| "ATG10", | |
| "NOTCH2", | |
| "BTLA", | |
| "ITGA5", | |
| "CCL13", | |
| "CCL2", | |
| "ACKR4", | |
| "ARHGDIB", | |
| "LCP2", | |
| "CLEC5A", | |
| "BAX", | |
| "SPP1", | |
| "KLRA1P", | |
| "CXCL11", | |
| "PSMC2", | |
| "IL10", | |
| "CD36", | |
| "CSF2", | |
| "AIRE", | |
| "CD7", | |
| "ABL1", | |
| "NOD2", | |
| "DEFB1", | |
| "STAT4", | |
| "IL22", | |
| "CD19", | |
| "CD1A", | |
| "NLRP3", | |
| "HLA-DRB3", | |
| "CD14", | |
| "CD79B", | |
| "AICDA", | |
| "ZBTB16", | |
| "MUC1", | |
| "FCER1A", | |
| "SELPLG", | |
| "PDCD1", | |
| "IL4", | |
| "IL13RA1", | |
| "IL21R", | |
| "MAP4K4", | |
| "LIF", | |
| "IL1RAP", | |
| "EDNRB", | |
| "B2M", | |
| "FCGR2B", | |
| "GP1BB", | |
| "CFD", | |
| "IL16", | |
| "GZMK", | |
| "KCNJ2", | |
| "EGR1", | |
| "MSR1", | |
| "IL1B", | |
| "BLNK", | |
| "IL21", | |
| "CFB", | |
| "ITGB1", | |
| "MX1", | |
| "ATG12", | |
| "CD4", | |
| "TLR4", | |
| "CD274", | |
| "SELE", | |
| "POU2F2", | |
| "TNFSF15", | |
| "TNFSF8", | |
| "CCR1", | |
| "CLU", | |
| "CUL9", | |
| "TOLLIP", | |
| "IL26", | |
| "IL2RA", | |
| "TGFBI", | |
| "CD1D", | |
| "IRF5", | |
| "TCF7", | |
| "ITLN2", | |
| "RAG1", | |
| "IL7R", | |
| "CXCL8", | |
| "MAPK11", | |
| "IFI16", | |
| "SLAMF6", | |
| "PDCD2", | |
| "TNFSF13B", | |
| "TIRAP", | |
| "ITGA2B", | |
| "PTPN2", | |
| "CD163", | |
| "TNFRSF17", | |
| "SLAMF1", | |
| "CXCR6", | |
| "UBE2L3", | |
| "IL32", | |
| "CCL16", | |
| "KLRG2", | |
| "IFNA2", | |
| "IRF3", | |
| "TRAF1", | |
| "MME", | |
| "IRAK1", | |
| "IRF4", | |
| "CX3CR1", | |
| "CD99", | |
| "CLEC6A", | |
| "ITGA4", | |
| "CR1", | |
| "CD164", | |
| "IL1RN", | |
| "CCL4", | |
| "CCR2", | |
| "CD70", | |
| "CTSC", | |
| "TAPBP", | |
| "PAX5", | |
| "TAGAP", | |
| "PRKCD", | |
| "ITGB2", | |
| "CD58", | |
| "HLA-C", | |
| "TNFRSF10C", | |
| "CLEC4E", | |
| "IFI35", | |
| "TLR1", | |
| "HAVCR2", | |
| "BCL10", | |
| "CASP8", | |
| "MYD88", | |
| "TCF4", | |
| "KLRG1", | |
| "STAT1", | |
| "LCK", | |
| "CASP10", | |
| "IL6R", | |
| "ITGAL", | |
| "PDCD1LG2", | |
| "IL12B", | |
| "PLA2G2E", | |
| "CXCL1", | |
| "IL3", | |
| "CD48", | |
| "IRAK4", | |
| "CD74", | |
| "HLA-DMB", | |
| "PSMB7", | |
| "CD96", | |
| "MIF", | |
| "MRC1", | |
| "NCAM1", | |
| "IL15", | |
| "NFATC1", | |
| "MS4A1", | |
| "IL17F", | |
| "TLR2", | |
| "TRAF4", | |
| "PML", | |
| "STAT3", | |
| "IL27", | |
| "IFNL1", | |
| "AHR", | |
| "CD40", | |
| "KIR3DL1", | |
| "IL2RG", | |
| "IL6ST", | |
| "PDGFB", | |
| "IKBKE", | |
| "CD276", | |
| "S100A8", | |
| "CCR10", | |
| "SYK", | |
| "ENTPD1", | |
| "TNFSF12", | |
| "CEACAM6", | |
| "PDGFRB", | |
| "CEACAM8", | |
| "CD34", | |
| "TLR9", | |
| "C5", | |
| "IFNAR1", | |
| "CD8A", | |
| "IFIH1", | |
| "C7", | |
| "XCL1", | |
| "ICAM1", | |
| "CASP2", | |
| "CCL23", | |
| "IL11RA", | |
| "CCL26", | |
| "STAT5A", | |
| "TLR5", | |
| "CD8B", | |
| "HAMP", | |
| "IL2RB", | |
| "KLRB1", | |
| "CXCL2", | |
| "NOTCH1", | |
| "C1QA", | |
| "TGFBR1", | |
| "PTGER4", | |
| "PSMD7", | |
| "ICAM3", | |
| "IL20", | |
| "TNFRSF9", | |
| "CSF1", | |
| "FCGRT", | |
| "LITAF", | |
| "PLAU", | |
| "IL18", | |
| "HLA-DPA1", | |
| "ARG2", | |
| "CSF2RB", | |
| "NFKBIZ", | |
| "SMAD5", | |
| "CEBPB", | |
| "IL10RA", | |
| "PRDM1", | |
| "ITGAM", | |
| "VCAM1", | |
| "NFKB2", | |
| "IRAK3", | |
| "TBK1", | |
| "RELB", | |
| "GATA3", | |
| "LILRB2", | |
| "TLR8", | |
| "IFNB1", | |
| "GPI", | |
| "GBP1", | |
| "C6", | |
| "THY1", | |
| "CD3D", | |
| "C9", | |
| "CD81", | |
| "NCF4", | |
| "C1QBP", | |
| "TFRC", | |
| "CDKN1A", | |
| "IL1RL2", | |
| "SERPING1", | |
| "TRAF6", | |
| "LAIR1", | |
| "FCGR2A", | |
| "TNFRSF11A", | |
| "CD5", | |
| "MASP1", | |
| "CCL18", | |
| "XCR1", | |
| "KIT", | |
| "CHUK", | |
| "CCL11", | |
| "IL5", | |
| "KLRF1", | |
| "ITGAE", | |
| "IKBKB", | |
| "KLRC1", | |
| "PLAUR", | |
| "TNFSF4", | |
| "ITGA6", | |
| "IKZF2", | |
| "PRF1", | |
| "C1S", | |
| "RTRAF", | |
| "LILRA6", | |
| "ADA", | |
| "STAT6", | |
| "BCL6", | |
| "MAF", | |
| "HLA-A", | |
| "CXCL12", | |
| "TGFBR2", | |
| "TNFRSF1B", | |
| "CD2", | |
| "NOD1", | |
| "HLA-B", | |
| "LAMP3", | |
| "CD6", | |
| "CCL7", | |
| "IFNL2", | |
| "CYBB", | |
| "TNFRSF13B", | |
| "C2", | |
| "CD83", | |
| "JAK3", | |
| "LTA", | |
| "LAG3", | |
| "BST1", | |
| "HLA-DPB1", | |
| "IL23R", | |
| "CXCL13", | |
| "GZMB", | |
| "CD44", | |
| "KIR3DL3", | |
| "MR1", | |
| "CCR5", | |
| "IL12A", | |
| "CX3CL1", | |
| "IFNGR1", | |
| "TNFRSF8", | |
| "PTPN6", | |
| "HLA-DRB1", | |
| "TYK2", | |
| "ARG1", | |
| "SOCS3", | |
| "ICOS", | |
| "IRF8", | |
| "IFIT2", | |
| "CLEC7A", | |
| "SOCS1", | |
| "LILRB1", | |
| "LY96", | |
| "LTF", | |
| "ICAM2", | |
| "LILRA1", | |
| "PLAAT4", | |
| "HLA-DOB", | |
| "GBP5", | |
| "PSMB9", | |
| "CD55", | |
| "TAP2", | |
| "LTBR", | |
| "ICOSLG", | |
| "IL9", | |
| "TNF", | |
| "CD28", | |
| "ICAM5", | |
| "ITGAX", | |
| "LGALS3", | |
| "DPP4", | |
| "IL13", | |
| "RUNX1", | |
| "CSF3R", | |
| "MAPK1", | |
| "IL19", | |
| "PIGR", | |
| "ILF3", | |
| "NOS2", | |
| "HLA-DMA", | |
| "JAK1", | |
| "IL18R1", | |
| "XBP1", | |
| "CMKLR1", | |
| "CD79A", | |
| "TRAF2", | |
| "IRF1", | |
| "LILRA5", | |
| "IDO1", | |
| "IKZF3", | |
| "LILRB3", | |
| "HLA-DQB1", | |
| "LEF1", | |
| "NCR1", | |
| "IL18RAP", | |
| "STAT5B", | |
| "TIGIT", | |
| "FCER1G", | |
| "SRC", | |
| "HLA-DRA", | |
| "TNFRSF14", | |
| "MASP2", | |
| "PPARG", | |
| "PTPN22", | |
| "SLAMF7", | |
| "CD247", | |
| "CASP3", | |
| "ZEB1", | |
| "ELP1", | |
| "CISH", | |
| "PTK2", | |
| "CD244", | |
| "SMAD3", | |
| "RAF1", | |
| "CFP", | |
| "PSMB8", | |
| "IL1R2", | |
| "IL17B", | |
| "ABCB1", | |
| "TICAM1", | |
| "LILRA3", | |
| "DUSP4", | |
| "IFITM1", | |
| "LILRA2", | |
| "TRAF3", | |
| "VTN", | |
| "C8G", | |
| "CD22", | |
| "CD24", | |
| "BID", | |
| "TGFB1", | |
| "MAP4K1", | |
| "CD209", | |
| "ITLN1", | |
| "KLRD1", | |
| "CLEC4A", | |
| "IL23A", | |
| "CXCL10", | |
| "CD82", | |
| "RORC", | |
| "MBL2", | |
| "LILRB4", | |
| "KLRC2", | |
| "CSF1R", | |
| "TAP1", | |
| "NFATC3", | |
| "CDH5", | |
| "KLRC4", | |
| "SH2D1A", | |
| "ATM", | |
| "GPR183", | |
| "LILRA4", | |
| "TBX21", | |
| "TNFSF10", | |
| "CXCR1", | |
| "CD27", | |
| "KIR3DL2", | |
| "NFIL3", | |
| "TNFRSF13C", | |
| "MARCO", | |
| "TNFRSF4", | |
| "SKI", | |
| "IL1RL1", | |
| "S100A9", | |
| "JAK2", | |
| "PLA2G2A", | |
| "PPBP", | |
| "CCR7", | |
| "C8A", | |
| "MAP4K2", | |
| "EOMES", | |
| "TAL1", | |
| "RELA", | |
| "IKBKG", | |
| "TNFAIP6", | |
| "CTSG", | |
| "IL12RB1", | |
| "TNFAIP3", | |
| "GFI1", | |
| "PECAM1", | |
| "CXCR4", | |
| "IFNAR2", | |
| "CAMP", | |
| "CCL24", | |
| "CXCL9", | |
| "TRAF5", | |
| "CASP1", | |
| "KLRF2", | |
| "SIGIRR", | |
| "NFKBIA", | |
| "IL2", | |
| "PYCARD", | |
| "CTSS", | |
| "KLRK1", | |
| "ICAM4", | |
| "IL22RA2", | |
| "PSMB10", | |
| "TLR7", | |
| "IFNG", | |
| "NFKB1", | |
| "GNLY", | |
| "STING1", | |
| "IL1A", | |
| "SELL", | |
| "ZAP70", | |
| "C8B", | |
| "CEACAM1", | |
| "MCL1", | |
| "CD3E", | |
| "GZMA", | |
| "ETS1", | |
| "STAT2" | |
| ], | |
| "Coefficient": [ | |
| 0.12028385717511023, | |
| 0.08927085915484896, | |
| -0.0836465486440748, | |
| 0.08100677072492894, | |
| -0.07903845232831724, | |
| -0.07763323178638694, | |
| 0.07458480167458749, | |
| 0.07093017115391342, | |
| -0.06984171552173127, | |
| 0.06834180827162205, | |
| 0.06753159507991142, | |
| -0.06674539549198602, | |
| 0.06598630300517953, | |
| -0.06281518298694262, | |
| -0.062293391605065807, | |
| 0.06135777362233128, | |
| -0.060194301825392475, | |
| -0.059395889048706414, | |
| 0.058256139292440244, | |
| 0.05755665873410213, | |
| -0.05654296834385571, | |
| -0.05648058301875837, | |
| 0.05642858909610065, | |
| 0.05634572955741121, | |
| -0.05594973908519751, | |
| -0.05592252705093379, | |
| -0.05528534800088093, | |
| 0.05494783104595233, | |
| 0.05481796959036606, | |
| -0.05286517891494027, | |
| 0.05213831573785417, | |
| 0.051650073751622845, | |
| -0.05158862992245615, | |
| -0.051573668615674785, | |
| 0.05135031145738317, | |
| 0.050982618247115426, | |
| 0.05030010049433547, | |
| 0.05008477860455731, | |
| 0.04966955464442632, | |
| -0.049116485114010615, | |
| 0.048816832426653356, | |
| -0.04854491682960875, | |
| 0.04815779534106584, | |
| 0.047889909111761685, | |
| -0.047427097181161185, | |
| -0.04627077648927929, | |
| 0.04560452939856738, | |
| 0.045524741616938175, | |
| 0.04549732394002123, | |
| 0.04511189069858851, | |
| -0.044709546145692794, | |
| -0.04432780077420343, | |
| 0.04423071677259189, | |
| 0.04368454776373899, | |
| -0.043589720399554985, | |
| 0.043207715280565065, | |
| -0.043087063061855356, | |
| -0.042918146786939636, | |
| -0.042453008116192806, | |
| 0.04236157590621227, | |
| 0.041900822634847124, | |
| 0.04112373194667848, | |
| -0.040254994811722705, | |
| 0.04019889513207146, | |
| 0.040191094181292936, | |
| 0.04004445432506468, | |
| 0.039828610025955995, | |
| -0.03982330382234305, | |
| -0.03968136192514344, | |
| -0.03956697131894159, | |
| 0.03954545842554623, | |
| 0.03948522615279508, | |
| 0.03938514925820618, | |
| -0.0393092674001153, | |
| 0.038582614686003, | |
| -0.03852306341233092, | |
| -0.037774132170015, | |
| -0.03776782092132819, | |
| 0.03770000669428344, | |
| 0.037208266986973354, | |
| 0.0368407409225361, | |
| -0.03640156828364287, | |
| 0.03640002684589325, | |
| 0.03638715067608567, | |
| 0.036166416070341045, | |
| 0.03604155193255663, | |
| -0.03596748935282945, | |
| -0.03584347784264797, | |
| -0.03575757170624851, | |
| 0.03575575114921986, | |
| 0.034856821259750204, | |
| 0.03454015728432017, | |
| 0.03434036405793761, | |
| -0.03396428183830409, | |
| 0.03389960877652284, | |
| -0.03388721408640627, | |
| 0.03382852182573885, | |
| 0.03362320365415015, | |
| 0.03362077146944206, | |
| -0.033562105389260286, | |
| -0.03337421484397532, | |
| 0.03320716574384831, | |
| 0.033198882843154746, | |
| 0.03313447222280811, | |
| -0.033033576275776806, | |
| -0.03280734882073853, | |
| -0.03272279383294955, | |
| -0.03257886644915043, | |
| 0.03247567010211901, | |
| -0.032273770329803476, | |
| -0.032235239767809065, | |
| -0.03213158660085872, | |
| -0.03170370502772699, | |
| -0.03154438452154681, | |
| -0.03144746244573483, | |
| 0.03141519662925099, | |
| 0.031404684234219785, | |
| -0.03132391460751607, | |
| -0.03129091999304844, | |
| -0.031179641290964486, | |
| 0.031173966768663682, | |
| -0.031165556679524007, | |
| -0.031131622198215223, | |
| -0.031103128579529522, | |
| -0.031075876584599666, | |
| -0.031064093378981774, | |
| 0.03027214680316248, | |
| 0.030260988933502007, | |
| 0.030104552355346512, | |
| 0.030044575741874167, | |
| 0.030010035537494387, | |
| 0.02978079916060111, | |
| 0.02965122537210208, | |
| -0.02960632854571287, | |
| 0.029521604678414873, | |
| -0.029422859376228162, | |
| -0.029255841451252183, | |
| -0.029069067047466216, | |
| 0.029046252186678313, | |
| 0.028782952542971862, | |
| -0.028717946306693592, | |
| -0.028528559719484543, | |
| 0.028485363414252427, | |
| -0.02843945891098547, | |
| -0.028435806090732898, | |
| 0.02842289555704559, | |
| -0.028391179237532503, | |
| -0.028239647827203885, | |
| 0.028179836898393974, | |
| 0.02781241563935316, | |
| 0.027796213083135908, | |
| -0.027666301807152863, | |
| -0.027647535024240735, | |
| -0.027602557526101877, | |
| -0.02758773458183446, | |
| -0.027430860337293778, | |
| 0.027265599276344258, | |
| 0.02721017912999989, | |
| 0.02718038704761943, | |
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| ], | |
| "Absolute Coefficient": [ | |
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| ] | |
| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 60.0, | |
| "precision": 35.27272727272727, | |
| "recall": 46.666666666666664, | |
| "f1": 39.1553544494721 | |
| }, | |
| "selection": { | |
| "precision": 9.44741532976827, | |
| "recall": 100.0, | |
| "f1": 17.263843648208468, | |
| "jaccard": 9.44741532976827 | |
| } | |
| } | |
| } |