{ | |
"significant_genes": { | |
"Variable": [ | |
"ATG5", | |
"BATF3", | |
"B3GAT1", | |
"BCL2L11", | |
"C1R", | |
"BTK", | |
"C4BPA", | |
"C1QB", | |
"BCAP31", | |
"APP", | |
"CXCR3", | |
"CD40LG", | |
"DEFB4A", | |
"IRAK2", | |
"CCL8", | |
"EBI3", | |
"HLA-DQA1", | |
"CD59", | |
"C3", | |
"LILRB5", | |
"MAPK14", | |
"CCL15", | |
"IL1R1", | |
"TP53", | |
"ADGRE2", | |
"EGR2", | |
"TLR3", | |
"HFE", | |
"BATF", | |
"FADD", | |
"CD9", | |
"BCL2", | |
"FKBP5", | |
"LTB4R", | |
"HRAS", | |
"DEFB103A", | |
"CXCR2", | |
"CIITA", | |
"PTGS2", | |
"CR2", | |
"BST2", | |
"CCL3", | |
"CD53", | |
"CD86", | |
"FYN", | |
"CTNNB1", | |
"IL4R", | |
"CARD9", | |
"PSMB5", | |
"CCL20", | |
"PTAFR", | |
"DEFB103B", | |
"SLC2A1", | |
"S1PR1", | |
"IL7", | |
"CCND3", | |
"IKZF1", | |
"BCL3", | |
"CCR8", | |
"CRADD", | |
"POLR1G", | |
"KLRC3", | |
"FCAR", | |
"NFATC2", | |
"ATG16L1", | |
"CD160", | |
"CD14", | |
"CCL5", | |
"IGF2R", | |
"IRF7", | |
"MAPKAPK2", | |
"IL6", | |
"MBP", | |
"CFI", | |
"CD80", | |
"NT5E", | |
"IRGM", | |
"FN1", | |
"CXCL11", | |
"TNFSF11", | |
"ATG12", | |
"ABL1", | |
"FAS", | |
"LCP2", | |
"CCL13", | |
"LTB4R2", | |
"CD79B", | |
"CD46", | |
"MALT1", | |
"IL17A", | |
"AIRE", | |
"CCL2", | |
"KLRA1P", | |
"NOTCH2", | |
"CCL22", | |
"FCER1A", | |
"FOXP3", | |
"CFH", | |
"DEFB1", | |
"ITGA5", | |
"SPP1", | |
"HLA-DRB3", | |
"CD19", | |
"RAG2", | |
"CCRL2", | |
"CD36", | |
"NOD2", | |
"IL13RA1", | |
"IL1RAP", | |
"ACKR4", | |
"SELPLG", | |
"IL22", | |
"SELE", | |
"MUC1", | |
"CFD", | |
"PSMC2", | |
"PDCD1", | |
"LIF", | |
"CCL19", | |
"IL21R", | |
"IL32", | |
"ZBTB16", | |
"BCL10", | |
"BTLA", | |
"CFB", | |
"MAP4K4", | |
"FCGR2B", | |
"CD274", | |
"GZMK", | |
"EGR1", | |
"IL16", | |
"NLRP3", | |
"ATG10", | |
"EDNRB", | |
"CD1D", | |
"IL10", | |
"IL1B", | |
"MX1", | |
"BLNK", | |
"SLAMF6", | |
"STAT4", | |
"CD7", | |
"IL4", | |
"IL7R", | |
"CD4", | |
"MSR1", | |
"POU2F2", | |
"AICDA", | |
"IL21", | |
"CCR6", | |
"TLR4", | |
"CLEC5A", | |
"IFI16", | |
"IRF5", | |
"BAX", | |
"PDCD2", | |
"CUL9", | |
"TOLLIP", | |
"GP1BB", | |
"CLU", | |
"TCF7", | |
"CX3CR1", | |
"PDCD1LG2", | |
"IL1RN", | |
"KCNJ2", | |
"ITGA2B", | |
"SLAMF1", | |
"TNFSF8", | |
"MAPK11", | |
"ITLN2", | |
"IL26", | |
"CSF2", | |
"CXCL8", | |
"TNFSF15", | |
"TNFRSF17", | |
"TNFSF13B", | |
"B2M", | |
"IRF3", | |
"KLRG1", | |
"IL2RA", | |
"HLA-C", | |
"CXCL1", | |
"ITGA4", | |
"CCR10", | |
"MME", | |
"IFI35", | |
"IL3", | |
"CD48", | |
"CD70", | |
"CCL4", | |
"ITGB1", | |
"PAX5", | |
"TIRAP", | |
"TGFBI", | |
"RAG1", | |
"CD1A", | |
"TAPBP", | |
"CD163", | |
"ARHGDIB", | |
"CLEC6A", | |
"IRAK1", | |
"CASP8", | |
"C5", | |
"CCL16", | |
"TAGAP", | |
"IFNA2", | |
"PTPN2", | |
"HLA-DMB", | |
"TCF4", | |
"TLR1", | |
"ADA", | |
"ABCB1", | |
"TRAF1", | |
"PRKCD", | |
"IRAK4", | |
"MIF", | |
"CTSC", | |
"CCR2", | |
"LCK", | |
"CASP10", | |
"C1QA", | |
"NCAM1", | |
"HAVCR2", | |
"ATG7", | |
"IRF4", | |
"IFNL1", | |
"CDKN1A", | |
"MS4A1", | |
"CD58", | |
"IL6R", | |
"UBE2L3", | |
"CCL26", | |
"PLA2G2E", | |
"ENTPD1", | |
"TRAF4", | |
"IL15", | |
"CD164", | |
"IL12B", | |
"PSMB7", | |
"IL10RA", | |
"CEACAM6", | |
"CXCR6", | |
"CLEC4E", | |
"MYD88", | |
"TNFRSF10C", | |
"CCR1", | |
"KLRG2", | |
"ITGB2", | |
"CD8B", | |
"IFNAR1", | |
"CCL23", | |
"BST1", | |
"CXCL12", | |
"TLR2", | |
"CD96", | |
"STAT1", | |
"TNFSF12", | |
"ICAM1", | |
"NFATC1", | |
"STAT3", | |
"SMAD5", | |
"CD99", | |
"CSF2RB", | |
"IFNB1", | |
"CD28", | |
"ICAM3", | |
"CSF1", | |
"IL2RG", | |
"STAT5A", | |
"MRC1", | |
"ITGAL", | |
"IKBKE", | |
"TGFBR1", | |
"TLR9", | |
"IL2RB", | |
"PDGFB", | |
"HLA-DPA1", | |
"CD8A", | |
"CD2", | |
"RELB", | |
"SYK", | |
"IL27", | |
"XCL1", | |
"IFIH1", | |
"CD276", | |
"CD3D", | |
"PRDM1", | |
"PML", | |
"CCL11", | |
"TNFRSF9", | |
"PTGER4", | |
"C1S", | |
"LILRB2", | |
"PDGFRB", | |
"S100A8", | |
"IL6ST", | |
"TLR5", | |
"ARG2", | |
"CD81", | |
"HAMP", | |
"PSMD7", | |
"CD55", | |
"KIR3DL1", | |
"PLAU", | |
"KLRB1", | |
"FCGRT", | |
"CD34", | |
"CD74", | |
"NOTCH1", | |
"ITGAM", | |
"CXCL2", | |
"HLA-DOB", | |
"TNFRSF1B", | |
"PLAUR", | |
"CEBPB", | |
"THY1", | |
"CMKLR1", | |
"TNFRSF11A", | |
"VCAM1", | |
"CCR5", | |
"IL20", | |
"IL18", | |
"CCL7", | |
"C6", | |
"TLR8", | |
"LAIR1", | |
"GPI", | |
"CD40", | |
"KLRC1", | |
"LAG3", | |
"PRF1", | |
"IKBKB", | |
"C7", | |
"CR1", | |
"LITAF", | |
"TGFBR2", | |
"NFKBIZ", | |
"KIT", | |
"JAK3", | |
"HLA-DPB1", | |
"IL11RA", | |
"RTRAF", | |
"CX3CL1", | |
"SOCS3", | |
"LILRA6", | |
"NCF4", | |
"IL5", | |
"GATA3", | |
"LILRA1", | |
"IL17F", | |
"MR1", | |
"FCGR2A", | |
"TRAF6", | |
"SERPING1", | |
"TNFSF4", | |
"IRAK3", | |
"ATM", | |
"BID", | |
"IFNL2", | |
"IL1RL2", | |
"CD83", | |
"NOD1", | |
"ICOS", | |
"C1QBP", | |
"KLRF1", | |
"CD6", | |
"TBK1", | |
"TYK2", | |
"CD247", | |
"XCR1", | |
"GBP1", | |
"BCL6", | |
"IFIT2", | |
"HLA-A", | |
"CXCL13", | |
"ICAM5", | |
"CEACAM8", | |
"ELP1", | |
"KIR3DL3", | |
"C9", | |
"NFKB2", | |
"CSF3R", | |
"IL23R", | |
"AHR", | |
"CD27", | |
"CASP2", | |
"CDH5", | |
"TFRC", | |
"GBP5", | |
"CYBB", | |
"HLA-B", | |
"NOS2", | |
"STAT6", | |
"LTA", | |
"SOCS1", | |
"MAPK1", | |
"ITGAE", | |
"CD244", | |
"ITGA6", | |
"LY96", | |
"PSMB9", | |
"IFNGR1", | |
"CCL18", | |
"CD24", | |
"RUNX1", | |
"TNFRSF8", | |
"LAMP3", | |
"ICOSLG", | |
"IL12A", | |
"GNLY", | |
"TNFSF10", | |
"RORC", | |
"IKZF3", | |
"PPARG", | |
"CLEC7A", | |
"LILRB1", | |
"TNFRSF13B", | |
"CHUK", | |
"TRAF3", | |
"IL9", | |
"CFP", | |
"ILF3", | |
"IRF1", | |
"HLA-DRB1", | |
"CASP3", | |
"IDO1", | |
"CTSG", | |
"TNFRSF14", | |
"RAF1", | |
"PTPN6", | |
"TIGIT", | |
"NCR1", | |
"DPP4", | |
"PTK2", | |
"IL18RAP", | |
"TAP2", | |
"IRF8", | |
"LILRA3", | |
"CD82", | |
"LTBR", | |
"ICAM4", | |
"PLAAT4", | |
"TNF", | |
"PTPN22", | |
"STAT5B", | |
"PIGR", | |
"HLA-DQB1", | |
"LGALS3", | |
"IL13", | |
"GZMB", | |
"HLA-DMA", | |
"ITGAX", | |
"JAK1", | |
"CD5", | |
"GZMA", | |
"IKZF2", | |
"LTF", | |
"IL18R1", | |
"KLRC4", | |
"MASP2", | |
"LEF1", | |
"KLRC2", | |
"XBP1", | |
"SLAMF7", | |
"MASP1", | |
"CD79A", | |
"TAL1", | |
"HLA-DRA", | |
"CD44", | |
"CASP1", | |
"SH2D1A", | |
"CXCR4", | |
"CSF1R", | |
"TICAM1", | |
"LILRA5", | |
"LILRB3", | |
"MBL2", | |
"PPBP", | |
"ICAM2", | |
"LILRA2", | |
"NFATC3", | |
"CCR7", | |
"CXCR1", | |
"LILRB4", | |
"TRAF2", | |
"VTN", | |
"EOMES", | |
"ARG1", | |
"TAP1", | |
"CXCL10", | |
"IL17B", | |
"CTSS", | |
"LILRA4", | |
"CEACAM1", | |
"IL1A", | |
"MAP4K2", | |
"IL1R2", | |
"IL19", | |
"SMAD3", | |
"IFITM1", | |
"IL1RL1", | |
"GFI1", | |
"ZEB1", | |
"CLEC4A", | |
"C2", | |
"KIR3DL2", | |
"CISH", | |
"C8B", | |
"IFNG", | |
"KLRD1", | |
"DUSP4", | |
"CXCL9", | |
"C8A", | |
"MCL1", | |
"FCER1G", | |
"TNFAIP6", | |
"CD22", | |
"PLA2G2A", | |
"PYCARD", | |
"S100A9", | |
"TLR7", | |
"CCL24", | |
"MAF", | |
"SRC", | |
"CAMP", | |
"TNFRSF4", | |
"IKBKG", | |
"SELL", | |
"TNFAIP3", | |
"IL2", | |
"ITLN1", | |
"JAK2", | |
"NFIL3", | |
"CD3E", | |
"RELA", | |
"KLRK1", | |
"IL23A", | |
"STAT2", | |
"TGFB1", | |
"PSMB10", | |
"IL22RA2", | |
"CD209", | |
"TNFRSF13C", | |
"ZAP70", | |
"MARCO", | |
"SIGIRR", | |
"TRAF5", | |
"IL12RB1", | |
"TBX21", | |
"ETS1", | |
"KLRF2", | |
"MAP4K1", | |
"PECAM1", | |
"SKI", | |
"STING1", | |
"IFNAR2", | |
"PSMB8", | |
"NFKB1", | |
"GPR183", | |
"NFKBIA", | |
"C8G" | |
], | |
"Coefficient": [ | |
0.11697126575200906, | |
-0.08833576539820454, | |
0.0777831049487349, | |
0.07770235587104173, | |
0.0744446110797551, | |
-0.07302513353796163, | |
-0.07253960201235589, | |
0.070335942772477, | |
0.07021076246421197, | |
0.06867139971599666, | |
0.06739564778981129, | |
0.06664608274154883, | |
-0.06556548149827808, | |
-0.06526285355158984, | |
-0.06478702004997983, | |
0.06278482342752133, | |
0.06212882064396317, | |
-0.05904115652547952, | |
0.05869151146973863, | |
-0.057872596176415096, | |
-0.057465349371751295, | |
0.05661549193387189, | |
0.056571182766462016, | |
-0.056522207648835754, | |
-0.056158820823426096, | |
-0.056145228023839054, | |
0.05583387440303021, | |
-0.05526495440660539, | |
0.05519632426898176, | |
-0.054658690391481246, | |
-0.054544993046823864, | |
0.054254417703296635, | |
-0.05351994972847362, | |
0.0521519328138513, | |
0.05180470837798427, | |
0.05167572482881654, | |
0.051592429252797535, | |
0.05094756871454689, | |
0.05061746206168232, | |
0.05054001654913172, | |
0.04932292704528234, | |
-0.04865747201117771, | |
0.0481456309404309, | |
-0.047851783330457136, | |
0.04712985229282497, | |
-0.04702881371158347, | |
0.04636624777752747, | |
-0.04616090836080898, | |
0.046072342628481505, | |
-0.046014659123412495, | |
0.045788289114456704, | |
0.04548704539022973, | |
0.04514466249836485, | |
-0.044476319491813514, | |
-0.04430126222478103, | |
0.0440846656138217, | |
-0.043860213273042264, | |
-0.043686740731689745, | |
0.04328520401144061, | |
-0.04299307508122573, | |
0.04289799210825479, | |
0.0424422706528732, | |
-0.04191755861625974, | |
-0.04189095751814506, | |
-0.041427210201263685, | |
0.040767209008337454, | |
0.04052981654030411, | |
0.040497946735381055, | |
-0.040458719916857545, | |
0.03984154880069582, | |
0.03965385564088478, | |
0.03943582134878342, | |
-0.03863832558896173, | |
0.03806180087896304, | |
-0.038025757448020496, | |
0.03798929313952089, | |
0.03786613409211933, | |
0.03754340517257253, | |
-0.037362246666507684, | |
-0.036942407408136556, | |
0.03682673814875259, | |
-0.03675538970801949, | |
0.03666567023188936, | |
-0.03653531757333785, | |
-0.03647042808772908, | |
0.03641122285508218, | |
-0.03635582952019415, | |
-0.03628018189633749, | |
-0.03574782389399862, | |
-0.03570794276932576, | |
-0.035662590062788796, | |
0.03526646912281157, | |
0.03522672754428453, | |
0.034952137638665885, | |
0.034857802706612165, | |
-0.03443550633844832, | |
-0.034429113647950774, | |
0.03421536469699002, | |
-0.03420481980218094, | |
0.0341232621630854, | |
0.033952094175411264, | |
-0.033916815473512364, | |
0.033824012230888316, | |
-0.03368314101193453, | |
0.033472965199452254, | |
-0.03336037811964334, | |
-0.03311823521658021, | |
0.032871903259757355, | |
-0.03260750504868388, | |
0.03232065570432016, | |
0.03231414586000461, | |
0.032282723387510544, | |
-0.03213469396210107, | |
-0.03181992050620957, | |
0.0316602784652461, | |
-0.03145894331491984, | |
0.03141731950389393, | |
0.031076554531560205, | |
0.030989465737572826, | |
0.030396646925760693, | |
0.03010979264180408, | |
-0.029942377026273972, | |
-0.02981549392411431, | |
-0.029788244958962398, | |
-0.02952819937312669, | |
0.02943496578119734, | |
-0.029379088587719954, | |
-0.02928504626570439, | |
-0.02925514063362403, | |
0.02924452665410589, | |
0.029229827151021338, | |
-0.029210606461432562, | |
0.0291134480716185, | |
0.028866804282408967, | |
0.028603483750005203, | |
-0.02847107570338095, | |
-0.02844642167796687, | |
0.028439864288973847, | |
0.02821767334538777, | |
0.028216814306008347, | |
-0.027983080511571872, | |
-0.027897309556242547, | |
0.027810513687711064, | |
-0.02745390450215677, | |
-0.027072268585136863, | |
-0.02704302201331591, | |
-0.026959806507931797, | |
-0.026737374985747527, | |
-0.02673108734459614, | |
-0.02661042835287813, | |
-0.026556255873612013, | |
-0.026545789330031908, | |
0.026534956790669407, | |
-0.02649407317335969, | |
0.026472658586343623, | |
-0.026372839203425494, | |
0.026325470154611893, | |
0.026236818943072476, | |
-0.026129111507187337, | |
-0.02599517384247593, | |
0.02598138709407938, | |
-0.025716317376247348, | |
0.025679117019475322, | |
0.025567670340469167, | |
-0.0255598427952231, | |
0.025490072919707674, | |
0.02538292361017513, | |
0.025346777356005868, | |
0.025250017901815195, | |
-0.025237991505557104, | |
-0.024936161495826028, | |
0.02491981080721805, | |
0.024892263608701365, | |
0.02468329901809906, | |
0.024595100910411227, | |
-0.024504643118157435, | |
-0.02446467671305025, | |
0.024450643547042874, | |
-0.02436968610538096, | |
-0.024356698288006278, | |
-0.02429423742670461, | |
0.0242895995591287, | |
-0.024084698973231452, | |
-0.024068463516851987, | |
-0.024011302160044, | |
0.023816535922372876, | |
-0.023768911234850157, | |
-0.02364580967982235, | |
0.02357465390489486, | |
-0.02355834777875871, | |
0.023527401088143208, | |
-0.023441898979644122, | |
-0.023430481697452363, | |
0.023124858983153963, | |
0.023099531417421278, | |
-0.023020188243763423, | |
0.022987615408931468, | |
0.022963595315195585, | |
0.022880966425881156, | |
-0.02259416676318767, | |
0.022563324352457247, | |
0.02246599864691708, | |
-0.022462322010485074, | |
-0.022389271656747544, | |
-0.02237370138863607, | |
-0.022300757125641973, | |
0.022211282341589537, | |
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"Absolute Coefficient": [ | |
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}, | |
"cv_performance": { | |
"prediction": { | |
"accuracy": 61.73913043478261, | |
"precision": 36.666666666666664, | |
"recall": 40.666666666666664, | |
"f1": 37.841269841269835 | |
}, | |
"selection": { | |
"precision": 9.44741532976827, | |
"recall": 100.0, | |
"f1": 17.263843648208468, | |
"jaccard": 9.44741532976827 | |
} | |
} | |
} |