| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BATF3", | |
| "BCL2L11", | |
| "C1R", | |
| "B3GAT1", | |
| "C4BPA", | |
| "BCAP31", | |
| "BTK", | |
| "C1QB", | |
| "CD40LG", | |
| "DEFB4A", | |
| "APP", | |
| "CCL8", | |
| "CXCR3", | |
| "HLA-DQA1", | |
| "IRAK2", | |
| "EBI3", | |
| "LILRB5", | |
| "CCL15", | |
| "C3", | |
| "MAPK14", | |
| "CD59", | |
| "BCL2", | |
| "TP53", | |
| "IL1R1", | |
| "EGR2", | |
| "HFE", | |
| "TLR3", | |
| "BATF", | |
| "FADD", | |
| "HRAS", | |
| "LTB4R", | |
| "CD9", | |
| "CCL3", | |
| "PTGS2", | |
| "FKBP5", | |
| "CD86", | |
| "CIITA", | |
| "BST2", | |
| "CR2", | |
| "CXCR2", | |
| "DEFB103A", | |
| "ADGRE2", | |
| "CD53", | |
| "ATG16L1", | |
| "CTNNB1", | |
| "DEFB103B", | |
| "CCL20", | |
| "PTAFR", | |
| "PSMB5", | |
| "CCND3", | |
| "CARD9", | |
| "BCL3", | |
| "FYN", | |
| "IL7", | |
| "IL4R", | |
| "NFATC2", | |
| "S1PR1", | |
| "CCL5", | |
| "SLC2A1", | |
| "IKZF1", | |
| "POLR1G", | |
| "MBP", | |
| "FCAR", | |
| "KLRC3", | |
| "CRADD", | |
| "CCR8", | |
| "IGF2R", | |
| "FN1", | |
| "IL6", | |
| "CD160", | |
| "CCL22", | |
| "IRF7", | |
| "NT5E", | |
| "ACKR4", | |
| "CCL13", | |
| "IL17A", | |
| "CCRL2", | |
| "MAPKAPK2", | |
| "IRGM", | |
| "CFI", | |
| "FOXP3", | |
| "ATG12", | |
| "LCP2", | |
| "CD80", | |
| "LTB4R2", | |
| "MALT1", | |
| "CD14", | |
| "TNFSF11", | |
| "CFH", | |
| "AIRE", | |
| "CD46", | |
| "NOTCH2", | |
| "FAS", | |
| "CCL2", | |
| "HLA-DRB3", | |
| "ABL1", | |
| "SPP1", | |
| "CD36", | |
| "ITGA5", | |
| "CD79B", | |
| "CXCL11", | |
| "ATG7", | |
| "IL22", | |
| "MUC1", | |
| "CFD", | |
| "DEFB1", | |
| "RAG2", | |
| "CD19", | |
| "NOD2", | |
| "SELE", | |
| "IL1RAP", | |
| "FCER1A", | |
| "ATG10", | |
| "MAP4K4", | |
| "KLRA1P", | |
| "PSMC2", | |
| "SELPLG", | |
| "LIF", | |
| "ZBTB16", | |
| "PDCD1", | |
| "NLRP3", | |
| "FCGR2B", | |
| "MX1", | |
| "IL13RA1", | |
| "GZMK", | |
| "IL32", | |
| "EDNRB", | |
| "IL16", | |
| "EGR1", | |
| "CCL19", | |
| "IL10", | |
| "BTLA", | |
| "CD7", | |
| "BLNK", | |
| "IL1B", | |
| "MSR1", | |
| "TNFSF15", | |
| "IL4", | |
| "CD274", | |
| "IL21", | |
| "IL21R", | |
| "GP1BB", | |
| "KCNJ2", | |
| "SLAMF6", | |
| "POU2F2", | |
| "STAT4", | |
| "BCL10", | |
| "BAX", | |
| "TOLLIP", | |
| "CLEC5A", | |
| "CUL9", | |
| "IL26", | |
| "TCF7", | |
| "TLR4", | |
| "PDCD2", | |
| "IL7R", | |
| "IFI16", | |
| "TNFSF8", | |
| "PDCD1LG2", | |
| "B2M", | |
| "ITGA4", | |
| "ITGA2B", | |
| "CD70", | |
| "KLRG1", | |
| "CD4", | |
| "CSF2", | |
| "CCL16", | |
| "CD48", | |
| "IRF5", | |
| "IL2RA", | |
| "CLEC6A", | |
| "TNFSF13B", | |
| "ITLN2", | |
| "TIRAP", | |
| "IL1RN", | |
| "IFI35", | |
| "ITGB1", | |
| "CD1D", | |
| "CD1A", | |
| "TGFBI", | |
| "SLAMF1", | |
| "MME", | |
| "CFB", | |
| "IRF3", | |
| "CCR1", | |
| "TNFRSF17", | |
| "CLU", | |
| "RAG1", | |
| "CXCL8", | |
| "HLA-DMB", | |
| "MAPK11", | |
| "AICDA", | |
| "IRF4", | |
| "TAPBP", | |
| "PRKCD", | |
| "IL3", | |
| "MS4A1", | |
| "CCR6", | |
| "IRAK1", | |
| "IFNA2", | |
| "PAX5", | |
| "CCL4", | |
| "CCL26", | |
| "CASP8", | |
| "CXCL1", | |
| "CX3CR1", | |
| "CD8B", | |
| "HAVCR2", | |
| "TNFRSF10C", | |
| "TRAF1", | |
| "ARHGDIB", | |
| "HLA-C", | |
| "CD163", | |
| "IL12B", | |
| "PSMB7", | |
| "IKBKE", | |
| "TCF4", | |
| "CTSC", | |
| "PTPN2", | |
| "IL6R", | |
| "IRAK4", | |
| "ENTPD1", | |
| "NCAM1", | |
| "UBE2L3", | |
| "TAGAP", | |
| "LCK", | |
| "TLR1", | |
| "CD28", | |
| "ABCB1", | |
| "IFNL1", | |
| "MYD88", | |
| "CXCR6", | |
| "C5", | |
| "IL27", | |
| "CDKN1A", | |
| "CCL23", | |
| "MIF", | |
| "ITGAL", | |
| "CD96", | |
| "IL10RA", | |
| "KLRG2", | |
| "BST1", | |
| "TRAF4", | |
| "CASP10", | |
| "PDGFB", | |
| "CCR2", | |
| "ITGB2", | |
| "CLEC4E", | |
| "CD164", | |
| "TNFSF12", | |
| "CD58", | |
| "TLR9", | |
| "C1QA", | |
| "IL2RG", | |
| "ICAM1", | |
| "PLA2G2E", | |
| "STAT1", | |
| "CSF1", | |
| "STAT3", | |
| "IL15", | |
| "CEACAM6", | |
| "NFATC1", | |
| "CD8A", | |
| "PML", | |
| "CCR10", | |
| "C6", | |
| "RELB", | |
| "IFNB1", | |
| "STAT5A", | |
| "ICAM3", | |
| "HLA-DPA1", | |
| "TLR2", | |
| "CD276", | |
| "XCL1", | |
| "CCL11", | |
| "SYK", | |
| "KLRB1", | |
| "CD99", | |
| "CR1", | |
| "IL6ST", | |
| "CSF2RB", | |
| "SMAD5", | |
| "ARG2", | |
| "CD40", | |
| "TNFRSF9", | |
| "IFIH1", | |
| "PRDM1", | |
| "KLRC1", | |
| "CD81", | |
| "TGFBR1", | |
| "PTGER4", | |
| "LILRB2", | |
| "GATA3", | |
| "CD34", | |
| "NOTCH1", | |
| "PLAU", | |
| "CD74", | |
| "CXCL12", | |
| "S100A8", | |
| "PSMD7", | |
| "CD55", | |
| "MRC1", | |
| "ADA", | |
| "IL11RA", | |
| "ITGAM", | |
| "IL2RB", | |
| "TLR8", | |
| "CX3CL1", | |
| "PDGFRB", | |
| "TLR5", | |
| "CXCL2", | |
| "KIT", | |
| "IL17F", | |
| "NFKBIZ", | |
| "KIR3DL1", | |
| "FCGRT", | |
| "IL20", | |
| "PRF1", | |
| "CD2", | |
| "PLAUR", | |
| "C7", | |
| "GPI", | |
| "IL1RL2", | |
| "LAG3", | |
| "TNFRSF1B", | |
| "XCR1", | |
| "CD3D", | |
| "CEBPB", | |
| "HAMP", | |
| "LITAF", | |
| "NCF4", | |
| "THY1", | |
| "IFNAR1", | |
| "KLRF1", | |
| "IL18", | |
| "IL5", | |
| "LILRA6", | |
| "VCAM1", | |
| "IRAK3", | |
| "TNFRSF11A", | |
| "LAIR1", | |
| "HLA-DOB", | |
| "NOD1", | |
| "IFNL2", | |
| "FCGR2A", | |
| "TRAF6", | |
| "HLA-DPB1", | |
| "MR1", | |
| "LTA", | |
| "SERPING1", | |
| "JAK3", | |
| "IKBKB", | |
| "RTRAF", | |
| "TNFSF4", | |
| "TBK1", | |
| "NFKB2", | |
| "SOCS3", | |
| "LILRA1", | |
| "GBP5", | |
| "TGFBR2", | |
| "CCR5", | |
| "BID", | |
| "ELP1", | |
| "IL23R", | |
| "GBP1", | |
| "NOS2", | |
| "HLA-A", | |
| "MAF", | |
| "CD6", | |
| "STAT6", | |
| "C1QBP", | |
| "CCL18", | |
| "CEACAM8", | |
| "CASP2", | |
| "CD24", | |
| "KIR3DL3", | |
| "TFRC", | |
| "CXCL13", | |
| "IL12A", | |
| "ICOS", | |
| "CCL7", | |
| "C1S", | |
| "BCL6", | |
| "TYK2", | |
| "LY96", | |
| "HLA-DMA", | |
| "CASP3", | |
| "ITGA6", | |
| "ITGAE", | |
| "CD82", | |
| "SOCS1", | |
| "LAMP3", | |
| "ICOSLG", | |
| "ICAM5", | |
| "CMKLR1", | |
| "IFNGR1", | |
| "CD83", | |
| "LILRB1", | |
| "TNFRSF13B", | |
| "PTPN6", | |
| "TNFRSF8", | |
| "MAPK1", | |
| "HLA-B", | |
| "CYBB", | |
| "CD247", | |
| "PSMB9", | |
| "TNFRSF14", | |
| "CLEC7A", | |
| "IL9", | |
| "CSF3R", | |
| "CD79A", | |
| "CD5", | |
| "ILF3", | |
| "HLA-DRB1", | |
| "GZMB", | |
| "GNLY", | |
| "PPARG", | |
| "CD244", | |
| "TNF", | |
| "C9", | |
| "AHR", | |
| "LTF", | |
| "PLAAT4", | |
| "IFIT2", | |
| "IL18RAP", | |
| "MASP1", | |
| "CISH", | |
| "IRF1", | |
| "IKZF3", | |
| "ARG1", | |
| "DUSP4", | |
| "CD27", | |
| "TAP2", | |
| "ATM", | |
| "CDH5", | |
| "RUNX1", | |
| "TIGIT", | |
| "IRF8", | |
| "PTPN22", | |
| "CD44", | |
| "LEF1", | |
| "JAK1", | |
| "PIGR", | |
| "C8A", | |
| "LGALS3", | |
| "HLA-DQB1", | |
| "CHUK", | |
| "RORC", | |
| "IKZF2", | |
| "XBP1", | |
| "IDO1", | |
| "LILRA3", | |
| "NCR1", | |
| "IL13", | |
| "TRAF2", | |
| "ITGAX", | |
| "LTBR", | |
| "TRAF3", | |
| "PTK2", | |
| "MASP2", | |
| "IL18R1", | |
| "LILRB3", | |
| "STAT5B", | |
| "CFP", | |
| "TNFSF10", | |
| "IFNAR2", | |
| "RAF1", | |
| "CXCR4", | |
| "CEACAM1", | |
| "SLAMF7", | |
| "KLRC4", | |
| "LILRA5", | |
| "TAL1", | |
| "EOMES", | |
| "HLA-DRA", | |
| "CLEC4A", | |
| "ZEB1", | |
| "CASP1", | |
| "IL1R2", | |
| "CXCR1", | |
| "GFI1", | |
| "CTSG", | |
| "ICAM4", | |
| "SH2D1A", | |
| "IL19", | |
| "MBL2", | |
| "KLRC2", | |
| "ICAM2", | |
| "IL17B", | |
| "LILRA4", | |
| "VTN", | |
| "C2", | |
| "LILRB4", | |
| "CSF1R", | |
| "KIR3DL2", | |
| "LILRA2", | |
| "CTSS", | |
| "SRC", | |
| "PPBP", | |
| "GZMA", | |
| "DPP4", | |
| "NFIL3", | |
| "TNFAIP6", | |
| "IL12RB1", | |
| "IFNG", | |
| "IL1A", | |
| "KLRD1", | |
| "TICAM1", | |
| "TAP1", | |
| "NFATC3", | |
| "C8G", | |
| "IL22RA2", | |
| "IL1RL1", | |
| "CXCL9", | |
| "CXCL10", | |
| "IL2", | |
| "RELA", | |
| "FCER1G", | |
| "MAP4K1", | |
| "KLRK1", | |
| "PSMB10", | |
| "MARCO", | |
| "C8B", | |
| "PLA2G2A", | |
| "TGFB1", | |
| "SIGIRR", | |
| "JAK2", | |
| "S100A9", | |
| "SMAD3", | |
| "SELL", | |
| "CD22", | |
| "TNFAIP3", | |
| "CD209", | |
| "SKI", | |
| "IKBKG", | |
| "ETS1", | |
| "STAT2", | |
| "MCL1", | |
| "KLRF2", | |
| "GPR183", | |
| "TBX21", | |
| "CCR7", | |
| "CAMP", | |
| "PYCARD", | |
| "NFKBIA", | |
| "TNFRSF4", | |
| "PSMB8", | |
| "CCL24", | |
| "TLR7", | |
| "ZAP70", | |
| "IL23A", | |
| "NFKB1", | |
| "ITLN1", | |
| "STING1", | |
| "PECAM1", | |
| "TRAF5", | |
| "TNFRSF13C", | |
| "CD3E", | |
| "MAP4K2", | |
| "IFITM1" | |
| ], | |
| "Coefficient": [ | |
| 0.11620922679262398, | |
| -0.08932170440613915, | |
| 0.08024120045921455, | |
| 0.07787768537956959, | |
| 0.0774526269552317, | |
| -0.07307219757858126, | |
| 0.07302094968682848, | |
| -0.07233718452155086, | |
| 0.0704873378521018, | |
| 0.06952977336410934, | |
| -0.06698912140426252, | |
| 0.06566787339262875, | |
| -0.06473818101588981, | |
| 0.06455897269114495, | |
| 0.06427105101353285, | |
| -0.06281195899718393, | |
| 0.06034440398355023, | |
| -0.06017241653975177, | |
| 0.06006731136377383, | |
| 0.05921820651927776, | |
| -0.058849783204697144, | |
| -0.058248424810949086, | |
| 0.05808555778073832, | |
| -0.05759653246235997, | |
| 0.05757560485082481, | |
| -0.05604123123408129, | |
| -0.05588389110367518, | |
| 0.05551120987575, | |
| 0.05476976923990061, | |
| -0.05406916397580336, | |
| 0.0532395274213745, | |
| 0.05281337676436244, | |
| -0.052740023781826254, | |
| -0.052512657894334, | |
| 0.05171446326244065, | |
| -0.05152712773354393, | |
| -0.05120150474970775, | |
| 0.051152691865202785, | |
| 0.05048192296178253, | |
| 0.050371958619818094, | |
| 0.0501804235083861, | |
| 0.04882692499758139, | |
| -0.0488019324257793, | |
| 0.047640695159629494, | |
| -0.047426076423117074, | |
| -0.04724220850227109, | |
| 0.046778072581599994, | |
| -0.04661016253092397, | |
| 0.04657379380987195, | |
| 0.0463825494756394, | |
| 0.04604620940830486, | |
| -0.046046109586785275, | |
| -0.04580211499932851, | |
| 0.04560302456992263, | |
| -0.04547983794016956, | |
| 0.044973414482047676, | |
| -0.04409087451203762, | |
| -0.04372934406660641, | |
| 0.04359938208203701, | |
| 0.04336246560055197, | |
| -0.04285408955657969, | |
| 0.04273042561118918, | |
| -0.04241737092987666, | |
| -0.042210306457495246, | |
| 0.04215161213820472, | |
| -0.041355154089536106, | |
| 0.04077259876380582, | |
| -0.04053771026792546, | |
| 0.04040128722461375, | |
| 0.04022925364328469, | |
| 0.04021523706950936, | |
| 0.03932466096547457, | |
| 0.03922502537569307, | |
| 0.03898647552749264, | |
| 0.038919453685928654, | |
| -0.03853230699874524, | |
| -0.0384614700598753, | |
| 0.03843542840708856, | |
| 0.03838846959024068, | |
| 0.03797188658339179, | |
| 0.03791793067662968, | |
| -0.03764645778406717, | |
| 0.0373225783624928, | |
| -0.03723226047532127, | |
| -0.03714389505060785, | |
| 0.03703524208006328, | |
| -0.03683007163968647, | |
| 0.0366774881109683, | |
| -0.036643495714270065, | |
| 0.03646174653634501, | |
| -0.036305083244196325, | |
| -0.03545835306445789, | |
| 0.03526842242347324, | |
| 0.03514612959762717, | |
| 0.035130968235433026, | |
| -0.03506318813278041, | |
| -0.03492217669170182, | |
| 0.03469900817408008, | |
| -0.0340694843771131, | |
| 0.0340165132760171, | |
| -0.033897797641892546, | |
| -0.03373211904665175, | |
| 0.03370449070854484, | |
| 0.03347322664776748, | |
| -0.03343376591592159, | |
| 0.033399568576572905, | |
| -0.033332016364717346, | |
| -0.03298599887346345, | |
| 0.032697798758117756, | |
| -0.032677502204040206, | |
| -0.03262910568143455, | |
| -0.03259126338702732, | |
| -0.032432719947233984, | |
| 0.03239746417722945, | |
| 0.03229236028824398, | |
| 0.032271840067414556, | |
| -0.03213035990485826, | |
| 0.03206467645023684, | |
| 0.03177391110913888, | |
| -0.031662713990619124, | |
| 0.031510359455230834, | |
| -0.03141532661868374, | |
| -0.0311245244814557, | |
| 0.03110262637179459, | |
| 0.030401474049569673, | |
| -0.030213371199256774, | |
| 0.02995975231553209, | |
| 0.029637064566344736, | |
| 0.029633467730136077, | |
| 0.029592598083966495, | |
| 0.02955133975406858, | |
| -0.029355912296233598, | |
| -0.029066534298537172, | |
| -0.028938962733346302, | |
| 0.028918911846661132, | |
| -0.02890696007917237, | |
| -0.02875095318938266, | |
| 0.028446163454645092, | |
| 0.028175236664537782, | |
| -0.028072140835339487, | |
| -0.028005542113971174, | |
| 0.027897134291483904, | |
| -0.02788848394094907, | |
| -0.027678292577270273, | |
| 0.02754516360743318, | |
| -0.02751903862634766, | |
| -0.027204680939726656, | |
| -0.02720136408430244, | |
| 0.026982437793800967, | |
| 0.026892295065021204, | |
| -0.026883193754049385, | |
| 0.02687551441692789, | |
| -0.026750931009163217, | |
| 0.026610523346646184, | |
| -0.02645615501100428, | |
| -0.02645291659387272, | |
| -0.026410114648742, | |
| 0.026402644079807188, | |
| 0.02608669120998033, | |
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| ], | |
| "Absolute Coefficient": [ | |
| 0.11620922679262398, | |
| 0.08932170440613915, | |
| 0.08024120045921455, | |
| 0.07787768537956959, | |
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| ] | |
| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 60.0, | |
| "precision": 33.66161616161616, | |
| "recall": 46.666666666666664, | |
| "f1": 38.38146167557933 | |
| }, | |
| "selection": { | |
| "precision": 9.44741532976827, | |
| "recall": 100.0, | |
| "f1": 17.263843648208468, | |
| "jaccard": 9.44741532976827 | |
| } | |
| } | |
| } |