| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BATF3", | |
| "BCL2L11", | |
| "B3GAT1", | |
| "C1R", | |
| "BCAP31", | |
| "C4BPA", | |
| "BTK", | |
| "C1QB", | |
| "CD40LG", | |
| "APP", | |
| "CXCR3", | |
| "DEFB4A", | |
| "CCL8", | |
| "IRAK2", | |
| "HLA-DQA1", | |
| "BCL2", | |
| "EBI3", | |
| "LILRB5", | |
| "MAPK14", | |
| "CCL15", | |
| "CD59", | |
| "ADGRE2", | |
| "C3", | |
| "TLR3", | |
| "BATF", | |
| "TP53", | |
| "HFE", | |
| "FADD", | |
| "IL1R1", | |
| "HRAS", | |
| "CD9", | |
| "EGR2", | |
| "CIITA", | |
| "LTB4R", | |
| "FKBP5", | |
| "CXCR2", | |
| "CD86", | |
| "DEFB103A", | |
| "PTGS2", | |
| "CD53", | |
| "BST2", | |
| "CCL20", | |
| "CR2", | |
| "BCL3", | |
| "CCL3", | |
| "PSMB5", | |
| "FYN", | |
| "ATG16L1", | |
| "CARD9", | |
| "PTAFR", | |
| "DEFB103B", | |
| "CTNNB1", | |
| "CCND3", | |
| "IL4R", | |
| "NFATC2", | |
| "IL7", | |
| "S1PR1", | |
| "CCR8", | |
| "SLC2A1", | |
| "KLRC3", | |
| "IKZF1", | |
| "FCAR", | |
| "MBP", | |
| "CCL5", | |
| "POLR1G", | |
| "CRADD", | |
| "IGF2R", | |
| "NT5E", | |
| "MALT1", | |
| "CCL22", | |
| "MAPKAPK2", | |
| "FN1", | |
| "IRGM", | |
| "AIRE", | |
| "CFI", | |
| "LTB4R2", | |
| "ATG12", | |
| "IL17A", | |
| "CFH", | |
| "IL6", | |
| "CCL13", | |
| "CD14", | |
| "CD79B", | |
| "ABL1", | |
| "CD160", | |
| "TNFSF11", | |
| "CD80", | |
| "IRF7", | |
| "FOXP3", | |
| "FAS", | |
| "CD46", | |
| "CCRL2", | |
| "CCL2", | |
| "CD19", | |
| "CXCL11", | |
| "LCP2", | |
| "ITGA5", | |
| "KLRA1P", | |
| "NOTCH2", | |
| "RAG2", | |
| "SPP1", | |
| "ACKR4", | |
| "IL22", | |
| "DEFB1", | |
| "ATG7", | |
| "FCER1A", | |
| "CD36", | |
| "MUC1", | |
| "ATG10", | |
| "HLA-DRB3", | |
| "SELE", | |
| "PSMC2", | |
| "CFD", | |
| "PDCD1", | |
| "NLRP3", | |
| "NOD2", | |
| "EGR1", | |
| "LIF", | |
| "CCL19", | |
| "MAP4K4", | |
| "IL1RAP", | |
| "SELPLG", | |
| "IL13RA1", | |
| "FCGR2B", | |
| "ZBTB16", | |
| "MX1", | |
| "BCL10", | |
| "IL21R", | |
| "IL4", | |
| "CFB", | |
| "IL10", | |
| "IL1B", | |
| "IFI16", | |
| "IL32", | |
| "CUL9", | |
| "IL16", | |
| "CD1D", | |
| "EDNRB", | |
| "TNFSF15", | |
| "GZMK", | |
| "BTLA", | |
| "IL21", | |
| "BLNK", | |
| "CD7", | |
| "MSR1", | |
| "IL1RN", | |
| "STAT4", | |
| "GP1BB", | |
| "KCNJ2", | |
| "TLR4", | |
| "CD274", | |
| "CSF2", | |
| "CLEC5A", | |
| "BAX", | |
| "POU2F2", | |
| "IL26", | |
| "TIRAP", | |
| "ITLN2", | |
| "IL7R", | |
| "TNFSF8", | |
| "IRF3", | |
| "CD48", | |
| "CD4", | |
| "TCF7", | |
| "ITGB1", | |
| "SLAMF6", | |
| "TOLLIP", | |
| "PDCD2", | |
| "CLEC6A", | |
| "ITGA2B", | |
| "ITGA4", | |
| "CCL16", | |
| "CCR1", | |
| "TNFSF13B", | |
| "KLRG1", | |
| "AICDA", | |
| "CD1A", | |
| "SLAMF1", | |
| "PDCD1LG2", | |
| "CLU", | |
| "TNFRSF17", | |
| "IRF5", | |
| "IL3", | |
| "CD70", | |
| "CXCL1", | |
| "CD163", | |
| "RAG1", | |
| "TGFBI", | |
| "B2M", | |
| "IL2RA", | |
| "CXCL8", | |
| "IRAK1", | |
| "CX3CR1", | |
| "MAPK11", | |
| "CCR2", | |
| "TAPBP", | |
| "IFNA2", | |
| "IFI35", | |
| "CTSC", | |
| "HLA-DMB", | |
| "CCR10", | |
| "CASP8", | |
| "PAX5", | |
| "IRF4", | |
| "IRAK4", | |
| "CCL4", | |
| "IL12B", | |
| "TLR1", | |
| "CCR6", | |
| "PTPN2", | |
| "TRAF1", | |
| "PRKCD", | |
| "TNFRSF10C", | |
| "CD58", | |
| "TAGAP", | |
| "C5", | |
| "UBE2L3", | |
| "MME", | |
| "HAVCR2", | |
| "IL6R", | |
| "KLRG2", | |
| "HLA-C", | |
| "LCK", | |
| "ENTPD1", | |
| "CD164", | |
| "CD8B", | |
| "C1QA", | |
| "CCL26", | |
| "MIF", | |
| "CDKN1A", | |
| "MYD88", | |
| "ADA", | |
| "TRAF4", | |
| "PLA2G2E", | |
| "TCF4", | |
| "NCAM1", | |
| "CD96", | |
| "ITGAL", | |
| "IKBKE", | |
| "MS4A1", | |
| "PSMB7", | |
| "IFNL1", | |
| "CASP10", | |
| "IL10RA", | |
| "CD99", | |
| "CXCR6", | |
| "IL27", | |
| "IL15", | |
| "STAT1", | |
| "ITGB2", | |
| "ARHGDIB", | |
| "CLEC4E", | |
| "IL2RG", | |
| "PML", | |
| "CD8A", | |
| "CXCL2", | |
| "ICAM1", | |
| "TLR2", | |
| "BST1", | |
| "IFNAR1", | |
| "CD28", | |
| "CD74", | |
| "STAT3", | |
| "CCL23", | |
| "TNFSF12", | |
| "CSF2RB", | |
| "RELB", | |
| "TLR9", | |
| "CD276", | |
| "MRC1", | |
| "STAT5A", | |
| "ICAM3", | |
| "HLA-DPA1", | |
| "CSF1", | |
| "NFATC1", | |
| "TNFRSF9", | |
| "PTGER4", | |
| "NOTCH1", | |
| "PLAU", | |
| "CXCL12", | |
| "XCL1", | |
| "SMAD5", | |
| "KLRB1", | |
| "CD81", | |
| "PDGFB", | |
| "IFIH1", | |
| "CD34", | |
| "IL6ST", | |
| "CEACAM6", | |
| "SYK", | |
| "CR1", | |
| "C6", | |
| "CD55", | |
| "IFNB1", | |
| "TLR5", | |
| "PRDM1", | |
| "LILRB2", | |
| "TGFBR1", | |
| "HAMP", | |
| "CEBPB", | |
| "KLRC1", | |
| "CD40", | |
| "FCGRT", | |
| "ITGAM", | |
| "IL17F", | |
| "S100A8", | |
| "VCAM1", | |
| "C7", | |
| "PSMD7", | |
| "CD3D", | |
| "GATA3", | |
| "IL2RB", | |
| "NFKBIZ", | |
| "IL11RA", | |
| "CCR5", | |
| "KIR3DL1", | |
| "TLR8", | |
| "CCL11", | |
| "HLA-A", | |
| "PLAUR", | |
| "LITAF", | |
| "TRAF6", | |
| "C1S", | |
| "RTRAF", | |
| "TNFRSF1B", | |
| "AHR", | |
| "TNFRSF11A", | |
| "CX3CL1", | |
| "IL5", | |
| "IKBKB", | |
| "BCL6", | |
| "PDGFRB", | |
| "C1QBP", | |
| "LAIR1", | |
| "CCL18", | |
| "IL20", | |
| "IL18", | |
| "THY1", | |
| "LAG3", | |
| "IRAK3", | |
| "PRF1", | |
| "JAK3", | |
| "ARG2", | |
| "ABCB1", | |
| "ARG1", | |
| "XCR1", | |
| "FCGR2A", | |
| "MR1", | |
| "CD2", | |
| "IL23R", | |
| "NOD1", | |
| "NCF4", | |
| "CD83", | |
| "KLRF1", | |
| "SERPING1", | |
| "HLA-DPB1", | |
| "GBP5", | |
| "BID", | |
| "LILRA6", | |
| "TGFBR2", | |
| "TNFSF4", | |
| "SOCS3", | |
| "TBK1", | |
| "TFRC", | |
| "KIT", | |
| "CASP2", | |
| "STAT6", | |
| "CD6", | |
| "IL12A", | |
| "KIR3DL3", | |
| "NFKB2", | |
| "LILRA1", | |
| "MAF", | |
| "IL1RL2", | |
| "HLA-DOB", | |
| "LTA", | |
| "TYK2", | |
| "IFNL2", | |
| "GBP1", | |
| "IFNGR1", | |
| "ITGA6", | |
| "ITGAE", | |
| "CMKLR1", | |
| "CLEC7A", | |
| "LILRB1", | |
| "TNFRSF13B", | |
| "HLA-B", | |
| "CCL7", | |
| "C9", | |
| "NOS2", | |
| "ELP1", | |
| "ICOS", | |
| "TNFRSF8", | |
| "CD24", | |
| "IFIT2", | |
| "CYBB", | |
| "CSF3R", | |
| "PSMB9", | |
| "LAMP3", | |
| "SOCS1", | |
| "ATM", | |
| "HLA-DRB1", | |
| "CD27", | |
| "LY96", | |
| "GPI", | |
| "ILF3", | |
| "ICOSLG", | |
| "IRF8", | |
| "MAPK1", | |
| "IKZF3", | |
| "CXCL13", | |
| "IL13", | |
| "CEACAM8", | |
| "IL9", | |
| "TNF", | |
| "PTPN6", | |
| "TAP2", | |
| "HLA-DMA", | |
| "IRF1", | |
| "ICAM5", | |
| "PLAAT4", | |
| "CD244", | |
| "CHUK", | |
| "CD5", | |
| "IL18RAP", | |
| "CD82", | |
| "PIGR", | |
| "LTBR", | |
| "MASP2", | |
| "NCR1", | |
| "CD247", | |
| "TNFRSF14", | |
| "RUNX1", | |
| "IDO1", | |
| "IKZF2", | |
| "MASP1", | |
| "LILRA3", | |
| "CD79A", | |
| "CFP", | |
| "PTK2", | |
| "HLA-DQB1", | |
| "RAF1", | |
| "XBP1", | |
| "RORC", | |
| "DUSP4", | |
| "TRAF3", | |
| "GZMB", | |
| "PTPN22", | |
| "SLAMF7", | |
| "LGALS3", | |
| "CD44", | |
| "LEF1", | |
| "PPARG", | |
| "TIGIT", | |
| "STAT5B", | |
| "ITGAX", | |
| "CDH5", | |
| "LTF", | |
| "LILRB3", | |
| "JAK1", | |
| "TRAF2", | |
| "KLRC2", | |
| "IL18R1", | |
| "IL19", | |
| "TNFSF10", | |
| "CASP3", | |
| "DPP4", | |
| "TICAM1", | |
| "ICAM2", | |
| "CISH", | |
| "LILRA2", | |
| "HLA-DRA", | |
| "GNLY", | |
| "LILRA5", | |
| "CLEC4A", | |
| "CASP1", | |
| "C2", | |
| "KLRD1", | |
| "TAL1", | |
| "VTN", | |
| "ZEB1", | |
| "MBL2", | |
| "TAP1", | |
| "IL1R2", | |
| "GFI1", | |
| "C8A", | |
| "CXCR1", | |
| "ICAM4", | |
| "GZMA", | |
| "CSF1R", | |
| "NFIL3", | |
| "SRC", | |
| "IFNG", | |
| "CTSS", | |
| "CXCL10", | |
| "CTSG", | |
| "KLRC4", | |
| "LILRA4", | |
| "NFATC3", | |
| "CEACAM1", | |
| "FCER1G", | |
| "KIR3DL2", | |
| "JAK2", | |
| "IL1RL1", | |
| "LILRB4", | |
| "IL17B", | |
| "SH2D1A", | |
| "MARCO", | |
| "EOMES", | |
| "PLA2G2A", | |
| "CD22", | |
| "IL1A", | |
| "IL22RA2", | |
| "ITLN1", | |
| "IFITM1", | |
| "KLRK1", | |
| "TNFAIP6", | |
| "IL23A", | |
| "SMAD3", | |
| "IKBKG", | |
| "PPBP", | |
| "RELA", | |
| "PSMB8", | |
| "S100A9", | |
| "SELL", | |
| "CCL24", | |
| "STAT2", | |
| "MAP4K1", | |
| "IL12RB1", | |
| "TNFRSF4", | |
| "C8B", | |
| "MAP4K2", | |
| "IFNAR2", | |
| "TNFRSF13C", | |
| "MCL1", | |
| "CXCR4", | |
| "CD3E", | |
| "ZAP70", | |
| "CCR7", | |
| "PSMB10", | |
| "IL2", | |
| "TBX21", | |
| "ETS1", | |
| "TGFB1", | |
| "CAMP", | |
| "PECAM1", | |
| "TNFAIP3", | |
| "SIGIRR", | |
| "NFKBIA", | |
| "C8G", | |
| "KLRF2", | |
| "SKI", | |
| "TRAF5", | |
| "CD209", | |
| "CXCL9", | |
| "GPR183", | |
| "NFKB1", | |
| "PYCARD", | |
| "STING1", | |
| "TLR7" | |
| ], | |
| "Coefficient": [ | |
| 0.11778032816938332, | |
| -0.08768780956664592, | |
| 0.07951784315248507, | |
| 0.07669383591969328, | |
| 0.07407652608918797, | |
| 0.07282690900880455, | |
| -0.07279268892026798, | |
| -0.07123533286112003, | |
| 0.06893935974089793, | |
| 0.0684937572556096, | |
| 0.06798957347983034, | |
| 0.06634847976637594, | |
| -0.06589948587785258, | |
| -0.0657331071378627, | |
| -0.06387120975906192, | |
| 0.06297719097836993, | |
| 0.062802739832715, | |
| 0.061420238142674964, | |
| -0.0612008865770241, | |
| -0.05928399836471467, | |
| 0.059000768188159046, | |
| -0.057731951064590475, | |
| -0.057263662448262455, | |
| 0.056181365019445866, | |
| 0.056144231595359015, | |
| 0.05586302444673819, | |
| -0.055778266276099955, | |
| -0.054983535042158395, | |
| -0.054122080395119766, | |
| 0.05401973977403033, | |
| 0.05390717451338965, | |
| -0.0531505589407343, | |
| -0.0530003976549271, | |
| 0.05290201787698689, | |
| 0.05260672859865212, | |
| -0.05231184711586358, | |
| 0.05221886472730909, | |
| -0.051984011049570594, | |
| 0.05082924796870321, | |
| 0.05053485316058223, | |
| 0.049883896922032114, | |
| 0.049444622292399903, | |
| -0.049314204024393855, | |
| 0.04877596443734918, | |
| -0.0470473254199141, | |
| -0.04683096774773502, | |
| 0.04673309969923385, | |
| 0.04635331801011957, | |
| -0.046112119541410077, | |
| -0.0461097105443567, | |
| 0.045731494495285616, | |
| 0.04547946311695167, | |
| -0.04539509276330433, | |
| 0.04512673444194688, | |
| 0.04509595223744073, | |
| -0.04455678240192783, | |
| -0.044064679063948856, | |
| -0.04367983882689701, | |
| 0.04354990544482649, | |
| 0.04353338059767443, | |
| 0.0426493197392219, | |
| -0.04240442133405054, | |
| -0.042354269285013936, | |
| -0.042340239137631096, | |
| 0.04216449943796392, | |
| 0.041972287906583264, | |
| -0.041758510738872455, | |
| -0.041027072741201084, | |
| 0.03963915420239053, | |
| -0.03910321880001496, | |
| 0.039071549436417656, | |
| 0.03884807767179106, | |
| 0.038454562097507, | |
| 0.03783098371216283, | |
| -0.03778845959517019, | |
| 0.037767276467276886, | |
| 0.03772076864074102, | |
| 0.03754950796352223, | |
| -0.03745726668315576, | |
| 0.03744109198922813, | |
| 0.037377869491212454, | |
| -0.03726619855764781, | |
| 0.03713468786528574, | |
| -0.03703313103329501, | |
| -0.03690954307160971, | |
| 0.03684180574916822, | |
| -0.036776956636343186, | |
| -0.0367168165004241, | |
| 0.036579740703386716, | |
| -0.03652080278722789, | |
| 0.036336606193290176, | |
| -0.03633344466674179, | |
| 0.03620723254374783, | |
| 0.03592917469588029, | |
| 0.035730944286793125, | |
| -0.035369035254991826, | |
| -0.035047874863637696, | |
| 0.03443959853167447, | |
| 0.034113437634004706, | |
| 0.034064076044645085, | |
| -0.03391926464074463, | |
| 0.03386545353349473, | |
| 0.03384955812149857, | |
| 0.03374368553102624, | |
| -0.03369519185310351, | |
| 0.03326432451517846, | |
| -0.03270558837542348, | |
| -0.03269318359504535, | |
| -0.03253281423929118, | |
| 0.0324518168203561, | |
| -0.03243428175521183, | |
| -0.031833947527906595, | |
| -0.03172177011543972, | |
| 0.03160714363289422, | |
| 0.031513172473136376, | |
| -0.0312359971228855, | |
| -0.0312324981859461, | |
| 0.031206565327326283, | |
| 0.030900775033391167, | |
| 0.03081009079102312, | |
| 0.030683738409866657, | |
| -0.030348238811483796, | |
| 0.030252162348700692, | |
| 0.030225543661515752, | |
| -0.029928615520144326, | |
| -0.02982522654681442, | |
| 0.029609709907403158, | |
| -0.029500615142367712, | |
| 0.029413258843123666, | |
| 0.029231760633427164, | |
| -0.02906523222804881, | |
| -0.028795809565875914, | |
| -0.02867696926807263, | |
| 0.028645385996947322, | |
| 0.028468068824203184, | |
| 0.02842187669516761, | |
| 0.028305002925332418, | |
| 0.02828362347783658, | |
| 0.028086977223873506, | |
| 0.02791846064168359, | |
| -0.02780377587710722, | |
| -0.027636165300494484, | |
| -0.027585326565947883, | |
| 0.027580853523033785, | |
| -0.027314887496775637, | |
| -0.027287799702797506, | |
| 0.027163351386827975, | |
| -0.02712291603415953, | |
| -0.027023788834737026, | |
| -0.02701617325115727, | |
| -0.026908147884152744, | |
| -0.026857725906646174, | |
| 0.026745019769538293, | |
| -0.026426284080144014, | |
| 0.026420983205070105, | |
| -0.02632678979163859, | |
| -0.025991748686339446, | |
| -0.02580269854457177, | |
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| ], | |
| "Absolute Coefficient": [ | |
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| ] | |
| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 60.8695652173913, | |
| "precision": 35.71428571428571, | |
| "recall": 47.33333333333333, | |
| "f1": 40.41102756892231 | |
| }, | |
| "selection": { | |
| "precision": 9.44741532976827, | |
| "recall": 100.0, | |
| "f1": 17.263843648208468, | |
| "jaccard": 9.44741532976827 | |
| } | |
| } | |
| } |