{ | |
"significant_genes": { | |
"Variable": [ | |
"ATG5", | |
"BATF3", | |
"BCL2L11", | |
"C1R", | |
"BCAP31", | |
"B3GAT1", | |
"C4BPA", | |
"BTK", | |
"CD40LG", | |
"APP", | |
"C1QB", | |
"DEFB4A", | |
"CXCR3", | |
"CCL8", | |
"IRAK2", | |
"HLA-DQA1", | |
"LILRB5", | |
"ADGRE2", | |
"MAPK14", | |
"EBI3", | |
"BCL2", | |
"C3", | |
"CD59", | |
"CCL15", | |
"TLR3", | |
"HRAS", | |
"TP53", | |
"CD86", | |
"IL1R1", | |
"FADD", | |
"BATF", | |
"CXCR2", | |
"CD9", | |
"HFE", | |
"EGR2", | |
"DEFB103A", | |
"LTB4R", | |
"CIITA", | |
"FKBP5", | |
"PTGS2", | |
"CD53", | |
"BST2", | |
"CR2", | |
"CCL20", | |
"PSMB5", | |
"CTNNB1", | |
"CCND3", | |
"CCL3", | |
"PTAFR", | |
"FYN", | |
"NFATC2", | |
"CARD9", | |
"S1PR1", | |
"CCL5", | |
"IL4R", | |
"DEFB103B", | |
"SLC2A1", | |
"CRADD", | |
"IKZF1", | |
"KLRC3", | |
"ACKR4", | |
"IL7", | |
"BCL3", | |
"FCAR", | |
"MBP", | |
"NT5E", | |
"POLR1G", | |
"CD80", | |
"CCR8", | |
"CCL22", | |
"ATG16L1", | |
"MALT1", | |
"IGF2R", | |
"FN1", | |
"FAS", | |
"AIRE", | |
"IL17A", | |
"IRGM", | |
"CD160", | |
"CD19", | |
"FOXP3", | |
"CFI", | |
"MAPKAPK2", | |
"TNFSF11", | |
"CD46", | |
"LTB4R2", | |
"IRF7", | |
"IL6", | |
"CD14", | |
"CD79B", | |
"CCRL2", | |
"CCL2", | |
"CFH", | |
"ABL1", | |
"CXCL11", | |
"HLA-DRB3", | |
"NOTCH2", | |
"KLRA1P", | |
"CCL13", | |
"LCP2", | |
"CFD", | |
"PSMC2", | |
"RAG2", | |
"ATG12", | |
"ITGA5", | |
"SPP1", | |
"DEFB1", | |
"NLRP3", | |
"ATG10", | |
"MAP4K4", | |
"MUC1", | |
"NOD2", | |
"CCL19", | |
"SELPLG", | |
"EGR1", | |
"FCGR2B", | |
"IL1RAP", | |
"FCER1A", | |
"CUL9", | |
"IL22", | |
"LIF", | |
"PDCD1", | |
"IL10", | |
"CD36", | |
"GZMK", | |
"IL13RA1", | |
"MX1", | |
"SELE", | |
"ZBTB16", | |
"IL4", | |
"EDNRB", | |
"ATG7", | |
"IL21R", | |
"CD1D", | |
"CFB", | |
"STAT4", | |
"TLR4", | |
"IL21", | |
"BLNK", | |
"BCL10", | |
"BTLA", | |
"PDCD2", | |
"IL1B", | |
"TNFSF15", | |
"IL16", | |
"ITLN2", | |
"CD4", | |
"CSF2", | |
"IL1RN", | |
"TNFSF8", | |
"GP1BB", | |
"POU2F2", | |
"IL26", | |
"TIRAP", | |
"ITGA2B", | |
"KCNJ2", | |
"IL32", | |
"IL7R", | |
"TNFSF13B", | |
"IL2RA", | |
"TOLLIP", | |
"CD7", | |
"CXCL8", | |
"KLRG1", | |
"BAX", | |
"CD48", | |
"CCR1", | |
"IFI16", | |
"MSR1", | |
"ITGB1", | |
"TCF7", | |
"SLAMF1", | |
"CD163", | |
"CCL16", | |
"CCR6", | |
"SLAMF6", | |
"B2M", | |
"CD274", | |
"TNFRSF17", | |
"IFI35", | |
"RAG1", | |
"CCR10", | |
"IL3", | |
"PDCD1LG2", | |
"CLEC6A", | |
"AICDA", | |
"CCR2", | |
"TGFBI", | |
"MAPK11", | |
"TAPBP", | |
"CX3CR1", | |
"CD70", | |
"IRF3", | |
"CD1A", | |
"TNFRSF10C", | |
"TRAF1", | |
"CLU", | |
"IRF4", | |
"CLEC5A", | |
"PAX5", | |
"ITGA4", | |
"C5", | |
"CD164", | |
"CASP10", | |
"TLR1", | |
"PTPN2", | |
"HLA-DMB", | |
"IFNA2", | |
"IRF5", | |
"PRKCD", | |
"KLRG2", | |
"TAGAP", | |
"CXCL1", | |
"MIF", | |
"LCK", | |
"C1QA", | |
"IRAK1", | |
"ADA", | |
"CCL4", | |
"NCAM1", | |
"PSMB7", | |
"MME", | |
"CXCR6", | |
"ENTPD1", | |
"CASP8", | |
"CD58", | |
"UBE2L3", | |
"IL6R", | |
"IFNL1", | |
"ITGB2", | |
"CCL26", | |
"HLA-C", | |
"MS4A1", | |
"CD8A", | |
"CD96", | |
"HAVCR2", | |
"CXCL12", | |
"IL12B", | |
"PML", | |
"IL10RA", | |
"CTSC", | |
"IL15", | |
"TLR2", | |
"IL2RG", | |
"IRAK4", | |
"TCF4", | |
"ICAM3", | |
"CD8B", | |
"STAT1", | |
"MYD88", | |
"ITGAL", | |
"CCL23", | |
"CDKN1A", | |
"IKBKE", | |
"PLA2G2E", | |
"CLEC4E", | |
"ICAM1", | |
"STAT3", | |
"HLA-DPA1", | |
"RELB", | |
"TRAF4", | |
"NFATC1", | |
"TLR9", | |
"PLAU", | |
"CSF2RB", | |
"ARHGDIB", | |
"TLR5", | |
"TNFSF12", | |
"CD81", | |
"ITGAM", | |
"CD99", | |
"MRC1", | |
"TGFBR1", | |
"XCL1", | |
"PDGFB", | |
"BST1", | |
"IL27", | |
"IFNAR1", | |
"TNFRSF9", | |
"CXCL2", | |
"IFNB1", | |
"IFIH1", | |
"KLRB1", | |
"STAT5A", | |
"IL20", | |
"PTGER4", | |
"NOTCH1", | |
"CCL11", | |
"CEACAM6", | |
"CD34", | |
"CD28", | |
"IL6ST", | |
"GATA3", | |
"KLRC1", | |
"CD276", | |
"VCAM1", | |
"HAMP", | |
"CD74", | |
"IL17F", | |
"S100A8", | |
"SYK", | |
"CSF1", | |
"PRDM1", | |
"LILRB2", | |
"CEBPB", | |
"CCR5", | |
"CCL18", | |
"TRAF6", | |
"LAIR1", | |
"IKBKB", | |
"TLR8", | |
"KIT", | |
"IL2RB", | |
"CD55", | |
"FCGR2A", | |
"CR1", | |
"HLA-A", | |
"LITAF", | |
"KIR3DL1", | |
"ARG2", | |
"C7", | |
"IL1RL2", | |
"PDGFRB", | |
"XCR1", | |
"C6", | |
"IL11RA", | |
"IFIT2", | |
"PLAUR", | |
"C1S", | |
"NOD1", | |
"MAF", | |
"AHR", | |
"FCGRT", | |
"PSMD7", | |
"NFKBIZ", | |
"IL18", | |
"TFRC", | |
"SERPING1", | |
"THY1", | |
"SMAD5", | |
"BID", | |
"NCF4", | |
"IRAK3", | |
"CMKLR1", | |
"PRF1", | |
"TNFRSF1B", | |
"C1QBP", | |
"CD3D", | |
"TGFBR2", | |
"CD2", | |
"IL5", | |
"LAG3", | |
"STAT6", | |
"HLA-DPB1", | |
"ARG1", | |
"NFKB2", | |
"LTA", | |
"ITGA6", | |
"KLRF1", | |
"GBP5", | |
"IL12A", | |
"CD40", | |
"IL23R", | |
"RTRAF", | |
"CD6", | |
"CX3CL1", | |
"LILRB1", | |
"SOCS3", | |
"TNFSF4", | |
"JAK3", | |
"TNFRSF11A", | |
"GBP1", | |
"LILRA6", | |
"TNFRSF13B", | |
"ICOSLG", | |
"TBK1", | |
"CEACAM8", | |
"IFNL2", | |
"CSF3R", | |
"ELP1", | |
"ITGAE", | |
"MR1", | |
"CD83", | |
"KIR3DL3", | |
"TNFRSF8", | |
"GPI", | |
"CXCL13", | |
"LAMP3", | |
"HLA-B", | |
"LILRA1", | |
"BCL6", | |
"LY96", | |
"HLA-DOB", | |
"ICOS", | |
"CCL7", | |
"TYK2", | |
"CYBB", | |
"PSMB9", | |
"IKZF2", | |
"ATM", | |
"PIGR", | |
"SOCS1", | |
"MASP1", | |
"IFNGR1", | |
"CLEC7A", | |
"NOS2", | |
"CD24", | |
"C9", | |
"DUSP4", | |
"ICAM5", | |
"IKZF3", | |
"CD244", | |
"NCR1", | |
"CD27", | |
"CHUK", | |
"PTPN6", | |
"IRF8", | |
"PLAAT4", | |
"ILF3", | |
"CD247", | |
"TAP2", | |
"TIGIT", | |
"CD82", | |
"HLA-DRB1", | |
"SLAMF7", | |
"TNFRSF14", | |
"TNF", | |
"CFP", | |
"MAPK1", | |
"CASP3", | |
"LILRA3", | |
"CD5", | |
"IL9", | |
"IRF1", | |
"CASP2", | |
"GZMB", | |
"IL18RAP", | |
"CDH5", | |
"RUNX1", | |
"LGALS3", | |
"HLA-DQB1", | |
"LTBR", | |
"HLA-DMA", | |
"PTPN22", | |
"RORC", | |
"LTF", | |
"ITGAX", | |
"ABCB1", | |
"PTK2", | |
"ICAM2", | |
"CD79A", | |
"TRAF2", | |
"RAF1", | |
"CD44", | |
"IL18R1", | |
"KLRC2", | |
"STAT5B", | |
"PPARG", | |
"XBP1", | |
"LEF1", | |
"IL1R2", | |
"MASP2", | |
"ITLN1", | |
"C2", | |
"CTSG", | |
"LILRA5", | |
"JAK1", | |
"CSF1R", | |
"CLEC4A", | |
"HLA-DRA", | |
"FCER1G", | |
"LILRB3", | |
"NFATC3", | |
"LILRA2", | |
"IFITM1", | |
"IDO1", | |
"TICAM1", | |
"CASP1", | |
"IL13", | |
"TRAF3", | |
"CISH", | |
"TNFSF10", | |
"ZEB1", | |
"IL12RB1", | |
"TAP1", | |
"IL19", | |
"GNLY", | |
"VTN", | |
"CTSS", | |
"CD3E", | |
"MARCO", | |
"KLRC4", | |
"MBL2", | |
"KLRD1", | |
"LILRA4", | |
"C8G", | |
"TAL1", | |
"SRC", | |
"PPBP", | |
"GFI1", | |
"SH2D1A", | |
"DPP4", | |
"ICAM4", | |
"IL1A", | |
"SKI", | |
"KIR3DL2", | |
"CXCL9", | |
"MAP4K2", | |
"MCL1", | |
"MAP4K1", | |
"IL17B", | |
"SMAD3", | |
"S100A9", | |
"LILRB4", | |
"JAK2", | |
"CXCR1", | |
"CEACAM1", | |
"NFIL3", | |
"TBX21", | |
"ZAP70", | |
"CD22", | |
"CXCR4", | |
"PLA2G2A", | |
"KLRF2", | |
"C8A", | |
"CD209", | |
"KLRK1", | |
"SELL", | |
"PSMB8", | |
"TNFRSF13C", | |
"TNFAIP6", | |
"CCL24", | |
"NFKBIA", | |
"PSMB10", | |
"TGFB1", | |
"IFNG", | |
"PYCARD", | |
"IL23A", | |
"RELA", | |
"IKBKG", | |
"EOMES", | |
"TNFRSF4", | |
"SIGIRR", | |
"CCR7", | |
"C8B", | |
"STING1", | |
"TNFAIP3", | |
"IL1RL1", | |
"TLR7", | |
"NFKB1", | |
"TRAF5", | |
"GPR183", | |
"PECAM1", | |
"ETS1", | |
"STAT2", | |
"IL2", | |
"CAMP", | |
"IFNAR2", | |
"CXCL10", | |
"GZMA", | |
"IL22RA2" | |
], | |
"Coefficient": [ | |
0.11825599609858768, | |
-0.08564850012485245, | |
0.08166354070780359, | |
0.07412218398539593, | |
0.07389811077659858, | |
0.07374000683657353, | |
-0.0711849751375066, | |
-0.07110277272134305, | |
0.06856366515518451, | |
0.06739531498787289, | |
0.06667835009541434, | |
-0.06663151978018476, | |
0.06593001835668108, | |
-0.06443095950592598, | |
-0.06356847500625769, | |
0.06348090074700552, | |
-0.062247210803719595, | |
-0.06172192944129169, | |
-0.061104084767369296, | |
0.059418900769801546, | |
0.05899773830965523, | |
0.05875456531329358, | |
-0.057902063526436995, | |
0.05777900845760545, | |
0.057733937765364646, | |
0.0573124933161631, | |
-0.056661686137631874, | |
-0.05576178966792785, | |
0.05573717255705143, | |
-0.055468906704160895, | |
0.05487213414029723, | |
0.05462338942656733, | |
-0.05451957339555469, | |
-0.054290240449858744, | |
-0.05412717290117307, | |
0.05402000965996356, | |
0.0525359956015513, | |
0.052525821693209726, | |
-0.05238163658946015, | |
0.05110094376469457, | |
0.050279914616174405, | |
0.05023483504605403, | |
0.05019226073487254, | |
-0.048986390774720105, | |
0.047212405271608, | |
-0.047136590286851264, | |
0.04703029687447701, | |
-0.046453019792032826, | |
0.046252583691615785, | |
0.045685508292356646, | |
-0.04554782168248647, | |
-0.044728408301043465, | |
-0.044262719125848525, | |
0.044236470442501535, | |
0.04421053952193411, | |
0.044134572147799554, | |
0.04383274124289735, | |
-0.043764222753316685, | |
-0.04357008455637357, | |
0.043187544581818456, | |
0.04288473867513999, | |
-0.04274499874891086, | |
-0.0425892826920701, | |
-0.042097636909886986, | |
-0.04187547127264145, | |
0.041764594778628684, | |
0.04148274450277982, | |
-0.04077482276758884, | |
0.04068173880328924, | |
0.04051933920329466, | |
-0.04015340405716469, | |
-0.03978234942786126, | |
-0.03942389996290049, | |
0.039083533380531985, | |
0.03899040080643043, | |
-0.038702115377108354, | |
-0.038600347883123026, | |
0.038578889417540715, | |
0.037904916436984765, | |
0.037764122428129134, | |
-0.03729810102010714, | |
0.037203511161624375, | |
0.03708763833274224, | |
-0.03704146843154916, | |
-0.03698769598224901, | |
0.036669026138026736, | |
0.036639071920149514, | |
0.036570781000825975, | |
0.036219265015262465, | |
-0.03617354343900341, | |
0.036150411068601666, | |
0.03570886374780653, | |
0.035680238352788315, | |
-0.03567632350512005, | |
-0.035521542110092036, | |
-0.03530048705060449, | |
0.03491960485825501, | |
0.0348166924308364, | |
-0.03467869518466564, | |
-0.03464025671867636, | |
0.034463447497272634, | |
-0.03430925455526838, | |
-0.03379338717712192, | |
0.03339423128565263, | |
0.03311898274715946, | |
0.033035770435463685, | |
-0.032744740181145864, | |
-0.03273084620828085, | |
0.032684426011805594, | |
0.032574565633503, | |
-0.03255400385121091, | |
-0.0321563740174234, | |
0.03178386816135618, | |
0.031719008369138865, | |
0.03156634254110306, | |
-0.031447691172284506, | |
-0.03142081728009843, | |
-0.031352024545032595, | |
0.031248808355143938, | |
0.03110112585086127, | |
0.030812264155719145, | |
0.030761729204241854, | |
-0.030752877105931883, | |
-0.030728506386216565, | |
-0.03065427371341055, | |
0.030604947181696738, | |
0.030275796759743758, | |
-0.030112923382801183, | |
-0.029698761622733605, | |
0.029647314342547835, | |
0.02950719166544177, | |
0.029454692138196535, | |
0.02932145296964553, | |
0.02892816927178287, | |
-0.028718615230094006, | |
-0.028704796599688578, | |
-0.02849027819640672, | |
-0.028455255136391064, | |
0.028419879525410856, | |
-0.028290969657201334, | |
-0.028148733078729758, | |
-0.027908512437849278, | |
-0.027880039484111514, | |
0.02758537530189246, | |
0.027504133247406398, | |
-0.02714756868669833, | |
-0.02675405500142577, | |
0.026727721897512376, | |
0.026633227119699048, | |
0.026630852318413476, | |
-0.026490776485729936, | |
-0.026327205758949087, | |
-0.02623702263118619, | |
-0.02605629228039177, | |
0.02605268900648646, | |
-0.02591821476220394, | |
0.025883333100321083, | |
-0.025845255008798727, | |
-0.025798879001449733, | |
-0.025650518105490735, | |
0.025513838948375826, | |
-0.025409982502459332, | |
0.025263001491184076, | |
-0.025136649861706252, | |
0.025005629325036107, | |
-0.025003862668818815, | |
0.024915261061515433, | |
0.024814958902931828, | |
-0.024699894287121698, | |
0.02464421161621316, | |
0.024596348235177916, | |
0.024595313367847878, | |
0.024545259070386845, | |
-0.024468581148145662, | |
-0.024364747917381392, | |
0.02428907821609277, | |
-0.02427540392425196, | |
-0.024166795756461038, | |
0.024127754534797537, | |
0.02406808944925738, | |
0.023935968622331494, | |
-0.023897235020158236, | |
-0.023870152042812193, | |
0.023804638859232015, | |
-0.023727276384714443, | |
-0.023679293535482506, | |
-0.023412857233404253, | |
0.023384130622286906, | |
0.023337733662713304, | |
0.02333107186287351, | |
-0.02332417919937642, | |
0.02329397794658044, | |
0.023257169175200147, | |
-0.02314368729563858, | |
-0.023125779826234434, | |
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0.022968295885341692, | |
-0.022966809914228583, | |
-0.022892678404730867, | |
-0.022620937190204235, | |
-0.02244329604522031, | |
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-0.022322084979809104, | |
-0.022259635542370676, | |
0.022173730685540627, | |
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], | |
"Absolute Coefficient": [ | |
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}, | |
"cv_performance": { | |
"prediction": { | |
"accuracy": 62.608695652173914, | |
"precision": 36.71428571428571, | |
"recall": 44.0, | |
"f1": 39.39194139194139 | |
}, | |
"selection": { | |
"precision": 9.44741532976827, | |
"recall": 100.0, | |
"f1": 17.263843648208468, | |
"jaccard": 9.44741532976827 | |
} | |
} | |
} |