| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BATF3", | |
| "BCL2L11", | |
| "BCAP31", | |
| "BTK", | |
| "C1R", | |
| "C4BPA", | |
| "CD40LG", | |
| "DEFB4A", | |
| "C1QB", | |
| "IRAK2", | |
| "APP", | |
| "CXCR3", | |
| "HLA-DQA1", | |
| "B3GAT1", | |
| "CCL8", | |
| "LILRB5", | |
| "EBI3", | |
| "FADD", | |
| "MAPK14", | |
| "HRAS", | |
| "TP53", | |
| "HFE", | |
| "C3", | |
| "CCL15", | |
| "CD59", | |
| "CIITA", | |
| "DEFB103A", | |
| "TLR3", | |
| "BCL2", | |
| "ADGRE2", | |
| "EGR2", | |
| "PTGS2", | |
| "BATF", | |
| "CD9", | |
| "IL1R1", | |
| "LTB4R", | |
| "CD86", | |
| "FKBP5", | |
| "BST2", | |
| "PSMB5", | |
| "CR2", | |
| "CXCR2", | |
| "S1PR1", | |
| "IKZF1", | |
| "FYN", | |
| "CCR8", | |
| "CARD9", | |
| "CCND3", | |
| "CTNNB1", | |
| "CD53", | |
| "CRADD", | |
| "NFATC2", | |
| "DEFB103B", | |
| "MBP", | |
| "ATG16L1", | |
| "CCL3", | |
| "PTAFR", | |
| "SLC2A1", | |
| "CCL20", | |
| "IL7", | |
| "FCAR", | |
| "IL4R", | |
| "CD14", | |
| "MALT1", | |
| "KLRC3", | |
| "NT5E", | |
| "ATG12", | |
| "CD79B", | |
| "MAPKAPK2", | |
| "CD160", | |
| "POLR1G", | |
| "FOXP3", | |
| "IRGM", | |
| "CCL5", | |
| "CCL22", | |
| "IGF2R", | |
| "IRF7", | |
| "CD46", | |
| "LTB4R2", | |
| "TNFSF11", | |
| "CXCL11", | |
| "IL17A", | |
| "CD19", | |
| "CD80", | |
| "IL6", | |
| "FN1", | |
| "LCP2", | |
| "CCL13", | |
| "CFH", | |
| "FAS", | |
| "AIRE", | |
| "MUC1", | |
| "KLRA1P", | |
| "CCL2", | |
| "BCL3", | |
| "LIF", | |
| "NOTCH2", | |
| "ACKR4", | |
| "PSMC2", | |
| "SELE", | |
| "ITGA5", | |
| "SPP1", | |
| "ABL1", | |
| "IL22", | |
| "ATG10", | |
| "CCRL2", | |
| "DEFB1", | |
| "CFI", | |
| "FCER1A", | |
| "HLA-DRB3", | |
| "PDCD1", | |
| "IL13RA1", | |
| "IL1RAP", | |
| "ZBTB16", | |
| "MX1", | |
| "SELPLG", | |
| "NLRP3", | |
| "MAP4K4", | |
| "CXCL1", | |
| "EDNRB", | |
| "IL1RN", | |
| "RAG2", | |
| "CFD", | |
| "IL32", | |
| "FCGR2B", | |
| "IL10", | |
| "CD36", | |
| "CFB", | |
| "POU2F2", | |
| "IL26", | |
| "ITLN2", | |
| "IL16", | |
| "TNFSF15", | |
| "NOD2", | |
| "IFI16", | |
| "IL4", | |
| "GP1BB", | |
| "TLR4", | |
| "GZMK", | |
| "IL21", | |
| "TOLLIP", | |
| "EGR1", | |
| "PDCD2", | |
| "SLAMF1", | |
| "BLNK", | |
| "CCR10", | |
| "CCR6", | |
| "CCL19", | |
| "CD4", | |
| "TIRAP", | |
| "BAX", | |
| "STAT4", | |
| "TNFSF13B", | |
| "MAPK11", | |
| "ATG7", | |
| "SLAMF6", | |
| "CD1D", | |
| "CLU", | |
| "TNFSF8", | |
| "IL21R", | |
| "B2M", | |
| "IRF3", | |
| "CD48", | |
| "TCF7", | |
| "IRAK4", | |
| "CUL9", | |
| "MSR1", | |
| "ITGA2B", | |
| "RAG1", | |
| "CD276", | |
| "IL3", | |
| "IRAK1", | |
| "CD164", | |
| "NCAM1", | |
| "IL7R", | |
| "CD58", | |
| "IL10RA", | |
| "CASP8", | |
| "IL1B", | |
| "CSF2", | |
| "CCL16", | |
| "IFI35", | |
| "TGFBI", | |
| "CXCL8", | |
| "CD1A", | |
| "PDCD1LG2", | |
| "CXCR6", | |
| "BTLA", | |
| "IL6R", | |
| "IL15", | |
| "CLEC6A", | |
| "TAPBP", | |
| "CX3CR1", | |
| "AICDA", | |
| "ITGB1", | |
| "IRF5", | |
| "HLA-DMB", | |
| "CD163", | |
| "CD70", | |
| "TRAF1", | |
| "TNFRSF17", | |
| "CCL4", | |
| "CD8B", | |
| "IL2RA", | |
| "LCK", | |
| "BCL10", | |
| "TNFRSF10C", | |
| "CLEC5A", | |
| "KLRG1", | |
| "CTSC", | |
| "PRKCD", | |
| "KLRG2", | |
| "TLR1", | |
| "MME", | |
| "CCR1", | |
| "KCNJ2", | |
| "ITGA4", | |
| "CD7", | |
| "UBE2L3", | |
| "PAX5", | |
| "IL12B", | |
| "HLA-C", | |
| "ENTPD1", | |
| "PTPN2", | |
| "CDKN1A", | |
| "IRF4", | |
| "CLEC4E", | |
| "IFNA2", | |
| "TAGAP", | |
| "HLA-DPA1", | |
| "MS4A1", | |
| "C1QA", | |
| "CD96", | |
| "CCR2", | |
| "MIF", | |
| "IFNAR1", | |
| "IFNL1", | |
| "TCF4", | |
| "ICAM3", | |
| "PSMB7", | |
| "IFNB1", | |
| "CD8A", | |
| "IFIH1", | |
| "ICAM1", | |
| "HAMP", | |
| "ITGB2", | |
| "PML", | |
| "CCL23", | |
| "TLR9", | |
| "MYD88", | |
| "STAT5A", | |
| "IKBKE", | |
| "TNFRSF9", | |
| "STAT3", | |
| "CASP10", | |
| "TLR2", | |
| "ITGAL", | |
| "TNFSF12", | |
| "PLA2G2E", | |
| "IL2RG", | |
| "BST1", | |
| "C5", | |
| "MRC1", | |
| "IL27", | |
| "STAT1", | |
| "CD40", | |
| "PLAU", | |
| "HAVCR2", | |
| "HLA-A", | |
| "CD274", | |
| "TRAF4", | |
| "ELP1", | |
| "NFATC1", | |
| "CD81", | |
| "ADA", | |
| "CD34", | |
| "PDGFB", | |
| "CCR5", | |
| "C7", | |
| "CD28", | |
| "ARHGDIB", | |
| "SMAD5", | |
| "IL17F", | |
| "CD74", | |
| "CD2", | |
| "IL2RB", | |
| "ITGAM", | |
| "CEACAM6", | |
| "CCL26", | |
| "CSF2RB", | |
| "RELB", | |
| "CEBPB", | |
| "KLRB1", | |
| "IL20", | |
| "IL11RA", | |
| "PTGER4", | |
| "NOD1", | |
| "TLR8", | |
| "LITAF", | |
| "VCAM1", | |
| "TNFRSF1B", | |
| "CXCL2", | |
| "KLRC1", | |
| "SYK", | |
| "CD99", | |
| "ARG1", | |
| "IL1RL2", | |
| "CD55", | |
| "IL5", | |
| "IL6ST", | |
| "IL23R", | |
| "C6", | |
| "S100A8", | |
| "LAIR1", | |
| "KIT", | |
| "IRAK3", | |
| "PRDM1", | |
| "CSF1", | |
| "TLR5", | |
| "IFIT2", | |
| "PSMD7", | |
| "IKBKB", | |
| "NOTCH1", | |
| "PRF1", | |
| "CXCL12", | |
| "ICOS", | |
| "LILRB2", | |
| "CMKLR1", | |
| "TGFBR1", | |
| "NFKBIZ", | |
| "BID", | |
| "CR1", | |
| "PLAUR", | |
| "C1QBP", | |
| "TFRC", | |
| "CD3D", | |
| "FCGR2A", | |
| "CX3CL1", | |
| "THY1", | |
| "CD83", | |
| "GBP1", | |
| "MR1", | |
| "CCL7", | |
| "LILRA6", | |
| "TNFRSF11A", | |
| "XCL1", | |
| "SOCS3", | |
| "KIR3DL1", | |
| "LAG3", | |
| "LTA", | |
| "RTRAF", | |
| "CXCL13", | |
| "FCGRT", | |
| "TNFSF4", | |
| "SERPING1", | |
| "TRAF6", | |
| "ABCB1", | |
| "TGFBR2", | |
| "MAF", | |
| "STAT6", | |
| "XCR1", | |
| "C1S", | |
| "JAK3", | |
| "NFKB2", | |
| "CDH5", | |
| "GBP5", | |
| "HLA-DPB1", | |
| "ICAM5", | |
| "LILRA1", | |
| "HLA-B", | |
| "IKZF3", | |
| "CD79A", | |
| "ICOSLG", | |
| "TBK1", | |
| "GPI", | |
| "LILRA3", | |
| "CD27", | |
| "BCL6", | |
| "PSMB9", | |
| "LY96", | |
| "GATA3", | |
| "IL18RAP", | |
| "NCF4", | |
| "IL1R2", | |
| "ARG2", | |
| "KLRF1", | |
| "MAPK1", | |
| "ITGAE", | |
| "IL9", | |
| "CSF3R", | |
| "LAMP3", | |
| "IFNL2", | |
| "HLA-DOB", | |
| "IL13", | |
| "MASP2", | |
| "RORC", | |
| "CD82", | |
| "TYK2", | |
| "ITLN1", | |
| "ITGA6", | |
| "CD5", | |
| "NCR1", | |
| "ILF3", | |
| "C9", | |
| "IL12A", | |
| "CLEC7A", | |
| "CYBB", | |
| "LILRB1", | |
| "IL18R1", | |
| "HLA-DMA", | |
| "KIR3DL3", | |
| "CCL18", | |
| "CCL11", | |
| "SLAMF7", | |
| "TIGIT", | |
| "PDGFRB", | |
| "CCR7", | |
| "SOCS1", | |
| "PTK2", | |
| "GZMB", | |
| "IRF8", | |
| "TNFRSF13B", | |
| "CEACAM8", | |
| "LTF", | |
| "IFNGR1", | |
| "TAP2", | |
| "HLA-DRB1", | |
| "PTPN22", | |
| "CTSG", | |
| "IKZF2", | |
| "IL1A", | |
| "CD6", | |
| "TNFSF10", | |
| "ATM", | |
| "TNFRSF14", | |
| "RUNX1", | |
| "CFP", | |
| "CCL24", | |
| "IL18", | |
| "STAT5B", | |
| "CD247", | |
| "HLA-DRA", | |
| "CD44", | |
| "LILRA2", | |
| "IFITM1", | |
| "CHUK", | |
| "PLAAT4", | |
| "TNFRSF8", | |
| "JAK1", | |
| "HLA-DQB1", | |
| "ITGAX", | |
| "LTBR", | |
| "PTPN6", | |
| "GNLY", | |
| "MBL2", | |
| "PIGR", | |
| "TRAF3", | |
| "LEF1", | |
| "XBP1", | |
| "IDO1", | |
| "SELL", | |
| "NOS2", | |
| "TNF", | |
| "LILRB3", | |
| "ICAM2", | |
| "TRAF2", | |
| "CXCL10", | |
| "IRF1", | |
| "KLRC2", | |
| "TAL1", | |
| "LGALS3", | |
| "JAK2", | |
| "CXCR4", | |
| "MAP4K2", | |
| "RAF1", | |
| "CD22", | |
| "IL19", | |
| "CD24", | |
| "CD209", | |
| "CD3E", | |
| "ICAM4", | |
| "TICAM1", | |
| "CD244", | |
| "DPP4", | |
| "CLEC4A", | |
| "KLRC4", | |
| "GFI1", | |
| "CEACAM1", | |
| "SH2D1A", | |
| "C8G", | |
| "PPARG", | |
| "NFIL3", | |
| "ZEB1", | |
| "TAP1", | |
| "IL17B", | |
| "GPR183", | |
| "ETS1", | |
| "KLRD1", | |
| "C2", | |
| "CAMP", | |
| "KLRK1", | |
| "TNFAIP6", | |
| "NFATC3", | |
| "GZMA", | |
| "CASP2", | |
| "VTN", | |
| "CXCL9", | |
| "NFKBIA", | |
| "LILRA4", | |
| "IL22RA2", | |
| "IFNAR2", | |
| "CASP3", | |
| "MASP1", | |
| "CSF1R", | |
| "MCL1", | |
| "LILRA5", | |
| "NFKB1", | |
| "PLA2G2A", | |
| "RELA", | |
| "C8B", | |
| "PSMB10", | |
| "C8A", | |
| "STAT2", | |
| "S100A9", | |
| "KLRF2", | |
| "PPBP", | |
| "KIR3DL2", | |
| "IL23A", | |
| "CASP1", | |
| "CXCR1", | |
| "CTSS", | |
| "TNFAIP3", | |
| "SIGIRR", | |
| "SMAD3", | |
| "DUSP4", | |
| "FCER1G", | |
| "CISH", | |
| "TRAF5", | |
| "SKI", | |
| "AHR", | |
| "EOMES", | |
| "MAP4K1", | |
| "IFNG", | |
| "TNFRSF13C", | |
| "IL12RB1", | |
| "TGFB1", | |
| "IKBKG", | |
| "ZAP70", | |
| "LILRB4", | |
| "IL1RL1", | |
| "TLR7", | |
| "SRC", | |
| "PECAM1", | |
| "STING1", | |
| "TNFRSF4", | |
| "TBX21", | |
| "IL2", | |
| "MARCO", | |
| "PYCARD", | |
| "PSMB8" | |
| ], | |
| "Coefficient": [ | |
| 0.12806620810417263, | |
| -0.09280300187563446, | |
| 0.08550336228037086, | |
| 0.07868398785024587, | |
| -0.0780233007074703, | |
| 0.07170102679662858, | |
| -0.07048834422158505, | |
| 0.06997998558836076, | |
| -0.06728919885169302, | |
| 0.06644998886134248, | |
| -0.06619583130431157, | |
| 0.06584251644825476, | |
| 0.06470359430461385, | |
| 0.06465056505857371, | |
| 0.06448763081806219, | |
| -0.0633563155748719, | |
| -0.06266625222547126, | |
| 0.06252763369212935, | |
| -0.06169118942140313, | |
| -0.06094722688341961, | |
| 0.056964870296035336, | |
| -0.0567669455222397, | |
| -0.056677715872143986, | |
| 0.05615262822950521, | |
| 0.05568562842737218, | |
| -0.05544148854952576, | |
| 0.054901224255154014, | |
| 0.05451628086015507, | |
| 0.053809393075514356, | |
| 0.05311917038013464, | |
| -0.05258200346331883, | |
| -0.05247650077974097, | |
| 0.05230495421917356, | |
| 0.05219338323636045, | |
| -0.05177772347293038, | |
| 0.05078706362462873, | |
| 0.05072906062810155, | |
| -0.05014073009341648, | |
| -0.04981574017240955, | |
| 0.04977543791614289, | |
| 0.04867166462647663, | |
| 0.04858823776658348, | |
| 0.048298707003423515, | |
| -0.04826536206624272, | |
| -0.04730959995016268, | |
| 0.046902513244303494, | |
| 0.0468354020657515, | |
| -0.04679353760430815, | |
| 0.04664642057022945, | |
| -0.046574016310885265, | |
| 0.046190315459267356, | |
| -0.04580733733478713, | |
| -0.04569557024515681, | |
| 0.04512089553190203, | |
| -0.045117194770424134, | |
| -0.04480776562155374, | |
| -0.04477373416315712, | |
| 0.04473211903827717, | |
| 0.044629921665685496, | |
| -0.044474157861512674, | |
| -0.04355095913027666, | |
| -0.04350358944670621, | |
| 0.043139650408216754, | |
| 0.042646801223246995, | |
| -0.04163127004035772, | |
| 0.04126759486130788, | |
| 0.04045037068336344, | |
| 0.0403045796292025, | |
| -0.03996584447263752, | |
| 0.03988057580316249, | |
| 0.0398157024794797, | |
| 0.03977396944282736, | |
| -0.03920256157449098, | |
| 0.03860978113121915, | |
| 0.03860699182391778, | |
| 0.037544943437851565, | |
| -0.03740722175508894, | |
| 0.037380838435471436, | |
| -0.03724617078917664, | |
| 0.037096943863750495, | |
| -0.03701285925570768, | |
| -0.03698840660009952, | |
| -0.03684956347365827, | |
| 0.03658853427788953, | |
| -0.036549562270438596, | |
| 0.03651647504599226, | |
| 0.03643571746393685, | |
| -0.03606935228550087, | |
| -0.03606137179926275, | |
| 0.03572224061487939, | |
| 0.03566867152242421, | |
| -0.03549560618629434, | |
| -0.035303374372382214, | |
| 0.03529874360811057, | |
| 0.03508862223599504, | |
| -0.035078096909472285, | |
| 0.03496324140059844, | |
| 0.03400265355842351, | |
| 0.03393949041392341, | |
| -0.03390655754148257, | |
| -0.0338886063600275, | |
| 0.03328333813113456, | |
| 0.03305321146027752, | |
| -0.032984579299573324, | |
| 0.032610166604244366, | |
| 0.03256463745827158, | |
| 0.032301965749043794, | |
| -0.032263837262468766, | |
| 0.03223742770437878, | |
| -0.031872384670018336, | |
| -0.031590509074293574, | |
| 0.031089414704315525, | |
| 0.03105778145864012, | |
| -0.030873438144683362, | |
| -0.030834227526603277, | |
| 0.030821592344284495, | |
| 0.030440075467308828, | |
| -0.030284588597178495, | |
| 0.030037142766598694, | |
| 0.03000050080784119, | |
| 0.02999328719658014, | |
| 0.029973250969812865, | |
| -0.029969716250775928, | |
| 0.02987957371847429, | |
| 0.029860742219056224, | |
| -0.02953776227365621, | |
| -0.02939753555600801, | |
| -0.029282594681170015, | |
| -0.028681102880594767, | |
| -0.02845488353802486, | |
| -0.028356328980974142, | |
| -0.028329486762837492, | |
| 0.028210192344108178, | |
| 0.02819844494580565, | |
| -0.028172413713267154, | |
| 0.0281210598529356, | |
| 0.027630994324276462, | |
| -0.02751505428472618, | |
| -0.02725519718110808, | |
| -0.027156465672383976, | |
| -0.027129497092387985, | |
| 0.026995353954249682, | |
| 0.026908422082019323, | |
| -0.026756219520358712, | |
| 0.026626393591234872, | |
| 0.02648268043117603, | |
| -0.026452361790505675, | |
| -0.02624192394301449, | |
| 0.02603185914958183, | |
| -0.025896574553887924, | |
| -0.02582491517188199, | |
| 0.025817293495763696, | |
| -0.025741647719820085, | |
| -0.025618334315467367, | |
| 0.025606434516485865, | |
| 0.025589128492376677, | |
| 0.025535341746577067, | |
| 0.025512067064359364, | |
| -0.025326171934134983, | |
| 0.025289699374658175, | |
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| 7.554558593094586e-05, | |
| 2.4250651992238204e-05 | |
| ], | |
| "Absolute Coefficient": [ | |
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| ] | |
| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 63.478260869565226, | |
| "precision": 38.16161616161616, | |
| "recall": 52.0, | |
| "f1": 42.967320261437905 | |
| }, | |
| "selection": { | |
| "precision": 9.454175555406746, | |
| "recall": 100.0, | |
| "f1": 17.275127206148472, | |
| "jaccard": 9.454175555406746 | |
| } | |
| } | |
| } |