{ | |
"significant_genes": { | |
"Variable": [ | |
"ATG5", | |
"BATF3", | |
"BCL2L11", | |
"BCAP31", | |
"BTK", | |
"C4BPA", | |
"C1R", | |
"DEFB4A", | |
"IRAK2", | |
"CD40LG", | |
"APP", | |
"C1QB", | |
"CCL8", | |
"CXCR3", | |
"B3GAT1", | |
"ADGRE2", | |
"LILRB5", | |
"HLA-DQA1", | |
"CCL15", | |
"MAPK14", | |
"EBI3", | |
"FADD", | |
"BCL2", | |
"TP53", | |
"CD59", | |
"TLR3", | |
"CIITA", | |
"C3", | |
"LTB4R", | |
"HRAS", | |
"HFE", | |
"EGR2", | |
"CCL20", | |
"DEFB103A", | |
"PTGS2", | |
"CD9", | |
"FYN", | |
"PSMB5", | |
"CR2", | |
"CD86", | |
"IL1R1", | |
"DEFB103B", | |
"FKBP5", | |
"BST2", | |
"CXCR2", | |
"BATF", | |
"CTNNB1", | |
"CRADD", | |
"S1PR1", | |
"PTAFR", | |
"IKZF1", | |
"CCR8", | |
"IL4R", | |
"CARD9", | |
"NFATC2", | |
"CCND3", | |
"CD14", | |
"IL7", | |
"CD53", | |
"MAPKAPK2", | |
"SLC2A1", | |
"MALT1", | |
"MBP", | |
"NT5E", | |
"CCL5", | |
"ATG16L1", | |
"CCL3", | |
"IL6", | |
"KLRC3", | |
"FCAR", | |
"FOXP3", | |
"ATG12", | |
"ABL1", | |
"FAS", | |
"CD79B", | |
"IRF7", | |
"CCL13", | |
"POLR1G", | |
"CD19", | |
"IL17A", | |
"IGF2R", | |
"CD46", | |
"LTB4R2", | |
"BCL3", | |
"FN1", | |
"CD80", | |
"ATG10", | |
"IRGM", | |
"TNFSF11", | |
"LCP2", | |
"CFI", | |
"CXCL11", | |
"SELE", | |
"LIF", | |
"CFD", | |
"AIRE", | |
"CCL2", | |
"NOTCH2", | |
"PSMC2", | |
"MAP4K4", | |
"SPP1", | |
"FCER1A", | |
"ITGA5", | |
"CCL19", | |
"IL13RA1", | |
"MUC1", | |
"KLRA1P", | |
"CFH", | |
"SELPLG", | |
"PDCD1", | |
"CCL22", | |
"CCRL2", | |
"MX1", | |
"RAG2", | |
"HLA-DRB3", | |
"ZBTB16", | |
"CD160", | |
"CD36", | |
"EDNRB", | |
"DEFB1", | |
"NOD2", | |
"AICDA", | |
"IL1RN", | |
"FCGR2B", | |
"IL32", | |
"ATG7", | |
"IL10", | |
"ACKR4", | |
"IL26", | |
"NLRP3", | |
"POU2F2", | |
"BCL10", | |
"EGR1", | |
"GZMK", | |
"IL1RAP", | |
"CFB", | |
"IFI16", | |
"MAPK11", | |
"IL22", | |
"CLU", | |
"BLNK", | |
"ITGA2B", | |
"IL4", | |
"CCL4", | |
"IL21R", | |
"TNFSF15", | |
"SLAMF1", | |
"IL16", | |
"TLR4", | |
"TOLLIP", | |
"RAG1", | |
"IRAK4", | |
"ITLN2", | |
"CCL16", | |
"CXCL8", | |
"CD1D", | |
"CD4", | |
"CASP8", | |
"STAT4", | |
"PDCD2", | |
"MSR1", | |
"TNFSF13B", | |
"CD1A", | |
"CUL9", | |
"SLAMF6", | |
"IL3", | |
"IFI35", | |
"TCF7", | |
"BTLA", | |
"TNFSF8", | |
"B2M", | |
"GP1BB", | |
"IL1B", | |
"CD7", | |
"BAX", | |
"CLEC6A", | |
"IL15", | |
"HLA-C", | |
"IL21", | |
"CXCL1", | |
"TIRAP", | |
"C1QA", | |
"NCAM1", | |
"IL7R", | |
"KLRG1", | |
"TGFBI", | |
"IL6R", | |
"IRF4", | |
"CD274", | |
"MME", | |
"KCNJ2", | |
"CD163", | |
"CLEC4E", | |
"IRF3", | |
"IRAK1", | |
"HLA-DMB", | |
"ENTPD1", | |
"PDCD1LG2", | |
"TNFRSF17", | |
"CX3CR1", | |
"CCR10", | |
"PLAU", | |
"CD70", | |
"PSMB7", | |
"CD48", | |
"TAPBP", | |
"IL10RA", | |
"CCR1", | |
"PRKCD", | |
"CSF2", | |
"TLR1", | |
"IRF5", | |
"CCL23", | |
"CCR6", | |
"CCR2", | |
"CD8B", | |
"PTPN2", | |
"TCF4", | |
"PAX5", | |
"CD58", | |
"ITGA4", | |
"CLEC5A", | |
"TRAF1", | |
"TAGAP", | |
"TNFRSF9", | |
"TLR9", | |
"IFNB1", | |
"CXCR6", | |
"IL2RA", | |
"KLRG2", | |
"UBE2L3", | |
"PDGFB", | |
"ITGB1", | |
"BST1", | |
"LCK", | |
"MS4A1", | |
"HAVCR2", | |
"IKBKE", | |
"HLA-DPA1", | |
"STAT3", | |
"TNFRSF10C", | |
"IFNL1", | |
"CTSC", | |
"CD164", | |
"IFNA2", | |
"CD8A", | |
"ICAM1", | |
"IL27", | |
"IL12B", | |
"TRAF4", | |
"ITGB2", | |
"CSF1", | |
"PLA2G2E", | |
"CDKN1A", | |
"ICAM3", | |
"MYD88", | |
"PML", | |
"IL6ST", | |
"CD96", | |
"IL2RG", | |
"STAT1", | |
"CSF2RB", | |
"TNFSF12", | |
"TLR2", | |
"STAT5A", | |
"C5", | |
"CEACAM6", | |
"MIF", | |
"IL20", | |
"C1QBP", | |
"C7", | |
"ARHGDIB", | |
"NFATC1", | |
"BID", | |
"ELP1", | |
"C6", | |
"KIT", | |
"IFNAR1", | |
"IL17F", | |
"ADA", | |
"ARG2", | |
"IL23R", | |
"CD28", | |
"CXCL13", | |
"CD276", | |
"CXCL12", | |
"RELB", | |
"ITGAL", | |
"KLRC1", | |
"IL11RA", | |
"XCL1", | |
"CD40", | |
"IFIH1", | |
"IL1RL2", | |
"SMAD5", | |
"PTGER4", | |
"HAMP", | |
"TGFBR1", | |
"ITGAM", | |
"CCL7", | |
"PRDM1", | |
"CCL26", | |
"VCAM1", | |
"ABCB1", | |
"CD55", | |
"CD3D", | |
"CD81", | |
"CD74", | |
"CASP10", | |
"LILRB2", | |
"NOTCH1", | |
"CX3CL1", | |
"MRC1", | |
"MR1", | |
"TLR5", | |
"SYK", | |
"GBP5", | |
"IL2RB", | |
"TLR8", | |
"CEBPB", | |
"S100A8", | |
"LAG3", | |
"LITAF", | |
"LTA", | |
"HLA-A", | |
"JAK3", | |
"TNFRSF1B", | |
"CXCL2", | |
"KLRB1", | |
"CD2", | |
"TNFRSF11A", | |
"PRF1", | |
"CD99", | |
"NFKBIZ", | |
"CR1", | |
"C1S", | |
"HLA-DPB1", | |
"FCGR2A", | |
"LAIR1", | |
"PLAUR", | |
"KIR3DL1", | |
"CCL11", | |
"FCGRT", | |
"TFRC", | |
"IKBKB", | |
"XCR1", | |
"IRAK3", | |
"LILRA6", | |
"ARG1", | |
"BCL6", | |
"CD34", | |
"IFNL2", | |
"CCL24", | |
"THY1", | |
"CCR5", | |
"CEACAM8", | |
"PSMD7", | |
"LILRA1", | |
"NOD1", | |
"CD247", | |
"ICOS", | |
"CASP2", | |
"SERPING1", | |
"CD79A", | |
"TBK1", | |
"SOCS3", | |
"NFKB2", | |
"STAT6", | |
"LY96", | |
"TGFBR2", | |
"CDH5", | |
"ILF3", | |
"NCF4", | |
"IFIT2", | |
"PSMB9", | |
"CD83", | |
"KLRF1", | |
"IL5", | |
"HLA-DOB", | |
"KIR3DL3", | |
"MAPK1", | |
"HLA-DMA", | |
"TNFSF4", | |
"MAF", | |
"PDGFRB", | |
"TRAF6", | |
"CSF3R", | |
"TYK2", | |
"RTRAF", | |
"CD27", | |
"GPI", | |
"HLA-B", | |
"TIGIT", | |
"NCR1", | |
"IL1A", | |
"ICOSLG", | |
"MASP2", | |
"LILRB1", | |
"HLA-DRB1", | |
"CD44", | |
"CCL18", | |
"ICAM4", | |
"CMKLR1", | |
"IL12A", | |
"TNFRSF13B", | |
"GATA3", | |
"ICAM5", | |
"GBP1", | |
"PTPN22", | |
"IL18RAP", | |
"CFP", | |
"CD5", | |
"TNFSF10", | |
"IL1R2", | |
"IRF8", | |
"ITGA6", | |
"IFNGR1", | |
"CD24", | |
"IL13", | |
"C8B", | |
"TNFRSF14", | |
"ITGAE", | |
"CXCL9", | |
"STAT5B", | |
"TNFRSF8", | |
"IKZF3", | |
"LTBR", | |
"LTF", | |
"CLEC7A", | |
"IL9", | |
"C8G", | |
"CYBB", | |
"ITGAX", | |
"LILRA3", | |
"IDO1", | |
"LAMP3", | |
"PTK2", | |
"NOS2", | |
"ITLN1", | |
"DPP4", | |
"PLAAT4", | |
"TNF", | |
"ICAM2", | |
"RORC", | |
"GZMB", | |
"CD82", | |
"SELL", | |
"CLEC4A", | |
"CD6", | |
"HLA-DQB1", | |
"TRAF2", | |
"LILRA2", | |
"C9", | |
"RAF1", | |
"CXCL10", | |
"KLRD1", | |
"LEF1", | |
"RUNX1", | |
"TRAF3", | |
"CXCR4", | |
"SLAMF7", | |
"SOCS1", | |
"LILRB3", | |
"IRF1", | |
"KLRC4", | |
"JAK1", | |
"CHUK", | |
"IL18", | |
"VTN", | |
"TAL1", | |
"LGALS3", | |
"CSF1R", | |
"CTSG", | |
"XBP1", | |
"TAP2", | |
"IKZF2", | |
"KLRF2", | |
"HLA-DRA", | |
"SH2D1A", | |
"IL17B", | |
"PPARG", | |
"PTPN6", | |
"CAMP", | |
"IL19", | |
"TAP1", | |
"IL18R1", | |
"ATM", | |
"GNLY", | |
"CASP3", | |
"GZMA", | |
"PIGR", | |
"PPBP", | |
"NFKBIA", | |
"LILRA4", | |
"MCL1", | |
"TICAM1", | |
"PSMB10", | |
"JAK2", | |
"KLRK1", | |
"MBL2", | |
"AHR", | |
"NFATC3", | |
"GFI1", | |
"KLRC2", | |
"MAP4K2", | |
"FCER1G", | |
"NFIL3", | |
"TNFAIP6", | |
"LILRA5", | |
"GPR183", | |
"IL22RA2", | |
"CCR7", | |
"ZEB1", | |
"TRAF5", | |
"IL23A", | |
"DUSP4", | |
"CD244", | |
"IKBKG", | |
"C2", | |
"MAP4K1", | |
"IFITM1", | |
"STAT2", | |
"S100A9", | |
"SRC", | |
"PSMB8", | |
"CD3E", | |
"IFNG", | |
"CXCR1", | |
"CTSS", | |
"ETS1", | |
"KIR3DL2", | |
"TNFAIP3", | |
"LILRB4", | |
"MARCO", | |
"MASP1", | |
"TLR7", | |
"C8A", | |
"ZAP70", | |
"CEACAM1", | |
"STING1", | |
"CISH", | |
"PLA2G2A", | |
"IL12RB1", | |
"SKI", | |
"NFKB1", | |
"CD209", | |
"EOMES", | |
"PECAM1", | |
"IFNAR2", | |
"TGFB1", | |
"SIGIRR", | |
"SMAD3", | |
"IL2", | |
"PYCARD", | |
"RELA", | |
"TNFRSF13C", | |
"IL1RL1", | |
"TNFRSF4", | |
"CASP1" | |
], | |
"Coefficient": [ | |
0.1217208095584659, | |
-0.08729757049253396, | |
0.08018261420045987, | |
0.07955721358933669, | |
-0.07693790602523792, | |
-0.07277532717480907, | |
0.07215477008513582, | |
-0.06926420600258924, | |
-0.06923783062665645, | |
0.06868808921438976, | |
0.06801177430132682, | |
0.06625137225487182, | |
-0.06512528814738529, | |
0.06391651538626793, | |
0.0638555466584569, | |
-0.06322766836015462, | |
-0.0626443693356834, | |
0.061960755669361545, | |
0.06189110144045331, | |
-0.0616543209989285, | |
0.06119047399882435, | |
-0.05872334824158377, | |
0.058640611013699676, | |
-0.057975270455217706, | |
-0.055459082839986976, | |
0.05530438608777182, | |
0.05393617426183428, | |
0.053915063201075066, | |
0.053533994389867834, | |
0.05331637274150385, | |
-0.05305935708980993, | |
-0.0525699258100021, | |
-0.05201631248656165, | |
0.05153639146684544, | |
0.050861292991885014, | |
-0.05044683705027886, | |
0.050389495300721926, | |
0.050003662874561615, | |
0.0499192730515808, | |
-0.04945743166322103, | |
0.04943613921226821, | |
0.048323277162806114, | |
-0.04752492754104108, | |
0.04746841657218986, | |
0.04746453943364488, | |
0.04738006085656431, | |
-0.047331060035712635, | |
-0.046735997051380616, | |
-0.046166583856505676, | |
0.04595503497352006, | |
-0.045108452276407786, | |
0.04509177120598333, | |
0.04475733992059876, | |
-0.04430676692767666, | |
-0.04425061638121146, | |
0.043860132650780106, | |
0.04364742088477962, | |
-0.043275190480863375, | |
0.04316038389143184, | |
0.04308175882022861, | |
0.04305534377844253, | |
-0.04229488424734663, | |
-0.042187529006924136, | |
0.04185203971203995, | |
0.04181342616977386, | |
-0.04167248912920106, | |
-0.04163160751281466, | |
0.04159852010543871, | |
0.04126541200217658, | |
-0.04071499618228703, | |
-0.04019179177966141, | |
0.04006008891172135, | |
-0.039963547493513295, | |
0.03960901879531568, | |
-0.03933875785666663, | |
0.03914226713830771, | |
-0.03872699865213287, | |
0.038612621756492924, | |
0.03853113389690566, | |
-0.03850703383372398, | |
-0.038328743706311626, | |
-0.03800501042724266, | |
0.03797763504051663, | |
-0.03700253062175539, | |
0.036206240521758096, | |
-0.036027694437541044, | |
0.03589492137079164, | |
0.03578072887530838, | |
-0.03531312497858144, | |
-0.03518465137180694, | |
0.03465507915965, | |
-0.0346517099252106, | |
-0.034557483232593555, | |
0.034290688394570314, | |
0.03413788419765408, | |
-0.033823959460256715, | |
0.03382320202571057, | |
0.033564863382734476, | |
-0.03343523227329256, | |
0.03338202325552999, | |
0.03333698293517807, | |
-0.033236752611619444, | |
0.033142781959532505, | |
0.03304469820155834, | |
0.03279149480596944, | |
-0.032678888589177196, | |
0.03255231896293983, | |
0.03231444521805544, | |
0.03211687744078256, | |
0.031907581012432545, | |
0.03183359643216974, | |
0.031530161975746346, | |
0.031525130575062996, | |
-0.03129241082844362, | |
-0.03099779179685633, | |
-0.030953398791640722, | |
0.030864044179633426, | |
-0.030775981108783598, | |
0.030371733718124825, | |
-0.03028018359764752, | |
-0.030053572169468207, | |
-0.030014602415285436, | |
0.02998185124319837, | |
-0.029977205086393423, | |
0.029911917366750473, | |
0.0298334532726482, | |
-0.029810980745186923, | |
0.02945793514388486, | |
-0.029384499979445748, | |
-0.029276365227183777, | |
-0.028844751846673195, | |
-0.028529792257921096, | |
0.02812841714728873, | |
-0.02811250337680461, | |
-0.028110228811372904, | |
-0.027525989249373328, | |
0.027324689970401647, | |
0.027251097747320856, | |
0.02714303324873207, | |
-0.027104170700030624, | |
0.026824515915101817, | |
0.026807830191506822, | |
0.026764392869250652, | |
-0.02671834220299505, | |
0.026666263076081016, | |
0.026558683477882525, | |
0.026481873650711685, | |
0.02646268929118365, | |
-0.026285209224663795, | |
0.0262408353032999, | |
0.02608279409634596, | |
-0.026022477870981713, | |
-0.026003338207050874, | |
-0.02590400200478795, | |
0.025847486688703233, | |
0.02578361518296197, | |
-0.02578147789294312, | |
0.025541165468622593, | |
-0.025518320313710353, | |
-0.025452007835537093, | |
-0.025443036917098958, | |
-0.02533053418171198, | |
-0.025090383349486316, | |
0.02506850434804097, | |
0.02496934789254304, | |
-0.024920846969975857, | |
0.024916591801335423, | |
0.024812129399705417, | |
-0.02479749042273446, | |
0.024425276428147673, | |
-0.024350947425779392, | |
-0.024199811035349263, | |
-0.024165722966824822, | |
-0.02414072972623873, | |
0.024000926120490304, | |
-0.0239980681918254, | |
-0.023846610215430213, | |
-0.023833963027024316, | |
-0.023812416292611858, | |
0.023751277605982488, | |
-0.023711496457755932, | |
-0.02367243178548548, | |
-0.023631247034420034, | |
-0.023325377333346723, | |
-0.023273969083488732, | |
0.023245864580372314, | |
0.023009506394312398, | |
0.022962830922616854, | |
-0.022938133102594894, | |
-0.02292650833871645, | |
-0.02289706304877019, | |
0.022884639626610977, | |
0.02284320885414255, | |
0.022735356108419803, | |
0.022634336589141258, | |
0.022481863866189344, | |
-0.022471272734726818, | |
0.022398377064771144, | |
0.022391088138757505, | |
-0.022045597884065214, | |
-0.022024166739734577, | |
-0.02186317391144993, | |
0.021827804839632377, | |
0.021755534150021363, | |
-0.021631040742156972, | |
0.021622979235903284, | |
0.02161802643646465, | |
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"Absolute Coefficient": [ | |
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}, | |
"cv_performance": { | |
"prediction": { | |
"accuracy": 62.60869565217392, | |
"precision": 37.27272727272727, | |
"recall": 52.0, | |
"f1": 42.30065359477125 | |
}, | |
"selection": { | |
"precision": 9.44741532976827, | |
"recall": 100.0, | |
"f1": 17.263843648208468, | |
"jaccard": 9.44741532976827 | |
} | |
} | |
} |