{ | |
"significant_genes": { | |
"Variable": [ | |
"ATG5", | |
"BATF3", | |
"BCL2L11", | |
"B3GAT1", | |
"CCL8", | |
"C4BPA", | |
"BTK", | |
"BCAP31", | |
"CD40LG", | |
"C1R", | |
"C1QB", | |
"APP", | |
"HLA-DQA1", | |
"DEFB4A", | |
"BCL2", | |
"EBI3", | |
"IRAK2", | |
"CXCR3", | |
"LILRB5", | |
"MAPK14", | |
"CD59", | |
"CCL15", | |
"CD9", | |
"HRAS", | |
"CCL20", | |
"FADD", | |
"TP53", | |
"C3", | |
"TLR3", | |
"CD86", | |
"IL1R1", | |
"FKBP5", | |
"LTB4R", | |
"ADGRE2", | |
"HFE", | |
"EGR2", | |
"PTGS2", | |
"CIITA", | |
"CD53", | |
"BATF", | |
"CR2", | |
"BCL3", | |
"DEFB103A", | |
"PSMB5", | |
"CCND3", | |
"CXCR2", | |
"DEFB103B", | |
"FYN", | |
"SLC2A1", | |
"PTAFR", | |
"CCR8", | |
"CARD9", | |
"CCL3", | |
"CRADD", | |
"MBP", | |
"BST2", | |
"S1PR1", | |
"CTNNB1", | |
"NFATC2", | |
"FCAR", | |
"POLR1G", | |
"IKZF1", | |
"IL4R", | |
"NT5E", | |
"KLRC3", | |
"CCL22", | |
"ATG12", | |
"CCL5", | |
"MALT1", | |
"MAPKAPK2", | |
"IRGM", | |
"CD14", | |
"CCRL2", | |
"CD46", | |
"FN1", | |
"IL7", | |
"TNFSF11", | |
"FOXP3", | |
"IRF7", | |
"ATG16L1", | |
"IGF2R", | |
"IL17A", | |
"IL6", | |
"CD80", | |
"LTB4R2", | |
"PSMC2", | |
"CD79B", | |
"RAG2", | |
"FAS", | |
"HLA-DRB3", | |
"SPP1", | |
"CD19", | |
"NOTCH2", | |
"LCP2", | |
"NLRP3", | |
"SELPLG", | |
"CCL13", | |
"ITGA5", | |
"IL1RAP", | |
"DEFB1", | |
"CFH", | |
"CXCL11", | |
"NOD2", | |
"AIRE", | |
"IL10", | |
"FCER1A", | |
"CFI", | |
"IL22", | |
"MUC1", | |
"CCR10", | |
"PDCD1", | |
"GZMK", | |
"ATG10", | |
"ATG7", | |
"CCL19", | |
"CFD", | |
"ADA", | |
"MAP4K4", | |
"MX1", | |
"CSF2", | |
"FCGR2B", | |
"SELE", | |
"KLRA1P", | |
"CD36", | |
"CCR1", | |
"KCNJ2", | |
"STAT4", | |
"IL4", | |
"POU2F2", | |
"IL13RA1", | |
"CCL2", | |
"CLEC5A", | |
"CD160", | |
"ABL1", | |
"TNFSF15", | |
"IL32", | |
"BLNK", | |
"IL1RN", | |
"TCF7", | |
"IL16", | |
"IFI16", | |
"IL7R", | |
"TLR4", | |
"ZBTB16", | |
"ITGB1", | |
"CUL9", | |
"MSR1", | |
"CCR2", | |
"ITLN2", | |
"EDNRB", | |
"CFB", | |
"ARHGDIB", | |
"CXCL1", | |
"IL21", | |
"ITGA4", | |
"TNFSF13B", | |
"CD274", | |
"CD48", | |
"TOLLIP", | |
"BAX", | |
"IL21R", | |
"HLA-DMB", | |
"CD1A", | |
"CD1D", | |
"AICDA", | |
"PDCD2", | |
"IL1B", | |
"CD4", | |
"GP1BB", | |
"SLAMF1", | |
"CD70", | |
"LIF", | |
"EGR1", | |
"ITGA2B", | |
"IL3", | |
"TNFSF8", | |
"CD163", | |
"CD7", | |
"IFNA2", | |
"PDCD1LG2", | |
"CXCL8", | |
"RAG1", | |
"IL26", | |
"CDKN1A", | |
"TNFRSF10C", | |
"BTLA", | |
"IRAK4", | |
"CTSC", | |
"HAVCR2", | |
"CLU", | |
"SLAMF6", | |
"TLR1", | |
"CD99", | |
"IRF3", | |
"IRAK1", | |
"CCR6", | |
"BID", | |
"TNFRSF17", | |
"KLRG1", | |
"CCL26", | |
"CCL16", | |
"TGFBI", | |
"ITGAL", | |
"CD58", | |
"IFI35", | |
"CLEC6A", | |
"PSMB7", | |
"TAGAP", | |
"CX3CR1", | |
"IL12B", | |
"LCK", | |
"MME", | |
"PAX5", | |
"CD8A", | |
"IL6R", | |
"IL10RA", | |
"IRF5", | |
"C6", | |
"TCF4", | |
"TAPBP", | |
"TRAF1", | |
"KLRG2", | |
"PLA2G2E", | |
"MAPK11", | |
"PRKCD", | |
"CASP10", | |
"NCAM1", | |
"IL2RA", | |
"CCL4", | |
"IL15", | |
"RELB", | |
"MYD88", | |
"HLA-C", | |
"STAT1", | |
"TIRAP", | |
"TNFSF12", | |
"TNFRSF9", | |
"ITGB2", | |
"IKBKE", | |
"PTPN2", | |
"IL27", | |
"IFIH1", | |
"IRF4", | |
"BCL10", | |
"CD164", | |
"CXCL2", | |
"IFNL1", | |
"TLR2", | |
"B2M", | |
"TGFBR1", | |
"CXCR6", | |
"UBE2L3", | |
"ITGAM", | |
"TLR5", | |
"HLA-DPA1", | |
"CEACAM6", | |
"CXCL12", | |
"IL2RG", | |
"CLEC4E", | |
"TRAF4", | |
"CD55", | |
"STAT3", | |
"ENTPD1", | |
"CD8B", | |
"PML", | |
"MRC1", | |
"CD96", | |
"C5", | |
"BST1", | |
"CEBPB", | |
"XCL1", | |
"TLR9", | |
"NOTCH1", | |
"CSF1", | |
"CD81", | |
"MS4A1", | |
"C1QBP", | |
"CCL23", | |
"ICAM3", | |
"CD276", | |
"KLRB1", | |
"ICAM1", | |
"NFATC1", | |
"CD83", | |
"CD34", | |
"MIF", | |
"CASP8", | |
"ACKR4", | |
"LITAF", | |
"KIR3DL1", | |
"IFNB1", | |
"CD74", | |
"CSF2RB", | |
"TNFRSF1B", | |
"IL17F", | |
"STAT5A", | |
"LILRB2", | |
"PTGER4", | |
"C7", | |
"ARG1", | |
"PLAU", | |
"SYK", | |
"IL6ST", | |
"PDGFRB", | |
"NFKBIZ", | |
"JAK3", | |
"IL2RB", | |
"IFNAR1", | |
"NFKB2", | |
"ARG2", | |
"PRDM1", | |
"TBK1", | |
"CCL11", | |
"PSMD7", | |
"CD2", | |
"CD28", | |
"IKBKB", | |
"IL20", | |
"SMAD5", | |
"FCGR2A", | |
"TRAF6", | |
"CCL18", | |
"THY1", | |
"CD40", | |
"IL11RA", | |
"GBP1", | |
"HAMP", | |
"HLA-DPB1", | |
"TLR8", | |
"CCR5", | |
"LY96", | |
"CR1", | |
"IL5", | |
"LTA", | |
"C1QA", | |
"CX3CL1", | |
"LILRB1", | |
"LAG3", | |
"KLRF1", | |
"FCGRT", | |
"CCL7", | |
"S100A8", | |
"XCR1", | |
"STAT6", | |
"TNFRSF11A", | |
"PLAUR", | |
"TGFBR2", | |
"VCAM1", | |
"KLRC1", | |
"NOD1", | |
"CASP2", | |
"RTRAF", | |
"NCF4", | |
"CD82", | |
"GBP5", | |
"CEACAM8", | |
"MAF", | |
"LAIR1", | |
"HLA-A", | |
"KIR3DL3", | |
"CXCL13", | |
"PDGFB", | |
"MR1", | |
"IL23R", | |
"TNFSF4", | |
"HLA-B", | |
"C2", | |
"IL1RL2", | |
"IFNGR1", | |
"IRAK3", | |
"CHUK", | |
"IL18RAP", | |
"CD6", | |
"MASP2", | |
"ICOSLG", | |
"CYBB", | |
"LILRA6", | |
"ILF3", | |
"PRF1", | |
"CD3D", | |
"IFNL2", | |
"TFRC", | |
"ITGA6", | |
"ELP1", | |
"LILRB3", | |
"PSMB9", | |
"CSF3R", | |
"IFIT2", | |
"HLA-DOB", | |
"KIT", | |
"IL12A", | |
"LILRA1", | |
"BCL6", | |
"PIGR", | |
"IRF8", | |
"IL18", | |
"CLEC7A", | |
"SERPING1", | |
"NCR1", | |
"GATA3", | |
"ICOS", | |
"TNFRSF8", | |
"PPARG", | |
"CMKLR1", | |
"C9", | |
"ITGAE", | |
"STAT5B", | |
"SOCS1", | |
"ICAM5", | |
"LAMP3", | |
"TNFRSF13B", | |
"PTPN6", | |
"ITGAX", | |
"CASP1", | |
"C1S", | |
"MAPK1", | |
"IDO1", | |
"SOCS3", | |
"LTF", | |
"ICAM2", | |
"JAK1", | |
"CD5", | |
"TNFRSF14", | |
"CSF1R", | |
"IL1R2", | |
"KLRC2", | |
"CXCL9", | |
"CD22", | |
"IRF1", | |
"IKZF3", | |
"TNFSF10", | |
"KLRC4", | |
"HLA-DRB1", | |
"PTK2", | |
"NOS2", | |
"TYK2", | |
"LGALS3", | |
"TAP2", | |
"CD79A", | |
"CASP3", | |
"SRC", | |
"LEF1", | |
"CD247", | |
"TNF", | |
"DUSP4", | |
"ICAM4", | |
"CAMP", | |
"IL9", | |
"CD27", | |
"PLAAT4", | |
"TAL1", | |
"DPP4", | |
"CCR7", | |
"ABCB1", | |
"VTN", | |
"GZMB", | |
"TIGIT", | |
"IL13", | |
"HLA-DQB1", | |
"PTPN22", | |
"XBP1", | |
"LILRA3", | |
"LTBR", | |
"CFP", | |
"MASP1", | |
"MBL2", | |
"IKZF2", | |
"GNLY", | |
"TRAF2", | |
"SLAMF7", | |
"IFITM1", | |
"TRAF3", | |
"LILRA5", | |
"C8A", | |
"HLA-DMA", | |
"CD24", | |
"RAF1", | |
"CD244", | |
"TAP1", | |
"CD44", | |
"LILRA2", | |
"IL19", | |
"LILRB4", | |
"IL1A", | |
"CDH5", | |
"IL18R1", | |
"RUNX1", | |
"CD3E", | |
"ZEB1", | |
"NFATC3", | |
"GPI", | |
"EOMES", | |
"CISH", | |
"ATM", | |
"CTSG", | |
"TICAM1", | |
"TNFRSF4", | |
"LILRA4", | |
"KLRD1", | |
"CCL24", | |
"RELA", | |
"SIGIRR", | |
"TLR7", | |
"CXCR1", | |
"ETS1", | |
"RORC", | |
"TNFAIP6", | |
"SH2D1A", | |
"KLRF2", | |
"PSMB8", | |
"MCL1", | |
"GPR183", | |
"CXCL10", | |
"IFNAR2", | |
"NFIL3", | |
"AHR", | |
"JAK2", | |
"IL22RA2", | |
"SELL", | |
"ZAP70", | |
"CLEC4A", | |
"MARCO", | |
"NFKBIA", | |
"KIR3DL2", | |
"PSMB10", | |
"S100A9", | |
"IL23A", | |
"IKBKG", | |
"STAT2", | |
"CEACAM1", | |
"NFKB1", | |
"PLA2G2A", | |
"HLA-DRA", | |
"GFI1", | |
"PPBP", | |
"IL2", | |
"C8G", | |
"IL17B", | |
"TGFB1", | |
"IFNG", | |
"CTSS", | |
"PYCARD", | |
"TBX21", | |
"TRAF5", | |
"KLRK1", | |
"C8B", | |
"CXCR4", | |
"PECAM1", | |
"SKI", | |
"GZMA", | |
"STING1", | |
"MAP4K1", | |
"IL12RB1", | |
"SMAD3", | |
"FCER1G", | |
"ITLN1", | |
"IL1RL1", | |
"MAP4K2", | |
"TNFRSF13C", | |
"CD209", | |
"TNFAIP3" | |
], | |
"Coefficient": [ | |
0.11816184037402001, | |
-0.08746409526712154, | |
0.07844329233596846, | |
0.07464039492574821, | |
-0.07173552866046341, | |
-0.07163284959775029, | |
-0.07025281433359601, | |
0.07006437152824822, | |
0.06917604398002773, | |
0.06867914468783512, | |
0.0682411387204432, | |
0.06822197075057816, | |
0.0671818644461455, | |
-0.06677887763763106, | |
0.0659556321022529, | |
0.0658913040596121, | |
-0.06278063743603372, | |
0.062402814796834544, | |
-0.0611046587412271, | |
-0.059961195150617604, | |
-0.05971484063480855, | |
0.05833475206644684, | |
-0.0578196868412483, | |
0.057659447578254225, | |
-0.05717192922829155, | |
-0.05707927289396534, | |
-0.05640101243199759, | |
0.05636447708393591, | |
0.05619643187249711, | |
-0.054826696455075805, | |
0.05429501830483278, | |
-0.053430500275541325, | |
0.053091443499478065, | |
-0.05214306300023186, | |
-0.05165926448750216, | |
-0.05159502385399431, | |
0.051260403827447176, | |
0.0506445505600449, | |
0.0503110722510736, | |
0.050085394633020267, | |
0.05000875348621303, | |
-0.04927999591736859, | |
0.04884459192094181, | |
0.04873136770985158, | |
0.048273765571122104, | |
0.048143406508923896, | |
0.04785314480342933, | |
0.04707321646467563, | |
0.04609306353313319, | |
0.04576768899801693, | |
0.04563146041297931, | |
-0.045371178922678175, | |
-0.04529591985531119, | |
-0.04527172818371021, | |
-0.04506029738233141, | |
0.04486954077674378, | |
-0.04478190530735861, | |
-0.04410529234292491, | |
-0.04363627690998776, | |
-0.04355016234657838, | |
0.04335638886080404, | |
-0.043190500226441435, | |
0.04313157094889403, | |
0.04263280482395168, | |
0.04256610016584054, | |
0.04254321025847807, | |
0.041736138895077164, | |
0.0417235783240407, | |
-0.04117314196940685, | |
0.04115825924667704, | |
0.040836589107761063, | |
0.04068171721000534, | |
0.040585114001688107, | |
-0.04028481215957312, | |
0.03991712830236324, | |
-0.03984985434905845, | |
-0.03927253695544977, | |
-0.03900501147374631, | |
0.038913037632955054, | |
-0.038074083715292764, | |
-0.03754618779962843, | |
-0.03749417878911064, | |
0.037487298659598454, | |
-0.037316858628051834, | |
0.036948274224507645, | |
-0.03653201693738966, | |
-0.03602271835677775, | |
-0.03598649866145559, | |
0.03596778876451459, | |
-0.03555992144809159, | |
0.03507707145474383, | |
0.03492603891170267, | |
0.03492126081036867, | |
-0.034634836427052305, | |
-0.03445787812806052, | |
0.034296784375296825, | |
-0.03427258567639398, | |
0.03410656556642921, | |
-0.03409623103509072, | |
-0.03399344293961035, | |
0.033979437891391275, | |
-0.03397922864916946, | |
-0.03364132618563577, | |
-0.03359540509373086, | |
-0.033535050835648825, | |
-0.03350482714439636, | |
0.0331826498760702, | |
0.033126778175359715, | |
-0.032812688913827756, | |
-0.03197411920208431, | |
0.03195311039059646, | |
-0.031934602535842925, | |
0.031583835308329665, | |
0.03154809536560359, | |
0.03146358789159566, | |
0.031356277718636284, | |
0.031335394570991555, | |
0.031142497597786083, | |
0.030935429898715772, | |
0.030908270611352855, | |
-0.030890175906781156, | |
-0.030621529208745495, | |
0.030025758694088262, | |
-0.030003300455342562, | |
0.02981782420998875, | |
-0.029241129379659718, | |
-0.029077240385561545, | |
0.028989580330839, | |
-0.02893782650851718, | |
0.02865959451173226, | |
0.028555564826068313, | |
-0.028202327531520816, | |
0.028157037824812124, | |
-0.028111758997612587, | |
0.02801189416152647, | |
0.027773614385530925, | |
0.027637904841268858, | |
0.027564727035283607, | |
0.027530130626292587, | |
0.027307842392195907, | |
0.027266271991134152, | |
-0.02724813851968435, | |
-0.027210177019707144, | |
-0.027165233722953038, | |
0.027026966481335866, | |
0.02702336110724436, | |
-0.027006598244122874, | |
-0.02691184861183956, | |
-0.026823466717693926, | |
0.02666192827832371, | |
-0.026616772037836228, | |
0.02646720694660734, | |
0.026452609994904834, | |
-0.026425285867179564, | |
-0.026375910070608674, | |
-0.026242933037158966, | |
-0.026196262217968426, | |
-0.02609894042180903, | |
0.026031462334723792, | |
0.02596596228606594, | |
0.025770277198781943, | |
0.025752781498143258, | |
-0.025739664178472177, | |
0.0256461207080195, | |
-0.02557402345935832, | |
-0.02556901052759688, | |
-0.025499323147048662, | |
-0.025496328063172258, | |
-0.025403727535827217, | |
0.025397437552397054, | |
0.025300541209448208, | |
0.02526741214578833, | |
0.02524953049056107, | |
0.024701969931071203, | |
-0.02467516658378152, | |
0.024649464010353866, | |
0.024487734792352306, | |
-0.024327916121150202, | |
-0.02422919445217519, | |
0.024125500103127386, | |
0.024101933422046064, | |
0.024051928322240294, | |
-0.02399381586617172, | |
-0.023914424430014656, | |
-0.023853563580579693, | |
-0.023770526783258302, | |
-0.02373999762721885, | |
0.02373722500243503, | |
-0.02372530499223441, | |
-0.023719837840481376, | |
0.023716028750587856, | |
-0.023646902548997702, | |
0.023644148963049696, | |
0.023545745733992724, | |
0.02352530986744164, | |
-0.023466616804936356, | |
0.02341059150498328, | |
0.02335005062602224, | |
-0.02302687571527069, | |
0.02291191187584173, | |
-0.022843505043951728, | |
0.022667891580821043, | |
0.02245761741158869, | |
-0.0224564645901625, | |
0.022279808946196543, | |
-0.02220155994496554, | |
0.022191535418108085, | |
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"Absolute Coefficient": [ | |
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}, | |
"cv_performance": { | |
"prediction": { | |
"accuracy": 61.73913043478261, | |
"precision": 35.88095238095238, | |
"recall": 44.0, | |
"f1": 38.82051282051282 | |
}, | |
"selection": { | |
"precision": 9.44741532976827, | |
"recall": 100.0, | |
"f1": 17.263843648208468, | |
"jaccard": 9.44741532976827 | |
} | |
} | |
} |