| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BATF3", | |
| "BCL2L11", | |
| "B3GAT1", | |
| "BCAP31", | |
| "C1R", | |
| "C4BPA", | |
| "BTK", | |
| "APP", | |
| "CD40LG", | |
| "C1QB", | |
| "CXCR3", | |
| "DEFB4A", | |
| "CCL8", | |
| "EBI3", | |
| "IRAK2", | |
| "HLA-DQA1", | |
| "CD59", | |
| "MAPK14", | |
| "LILRB5", | |
| "C3", | |
| "CCL15", | |
| "TLR3", | |
| "TP53", | |
| "BCL2", | |
| "EGR2", | |
| "FADD", | |
| "HFE", | |
| "IL1R1", | |
| "BATF", | |
| "HRAS", | |
| "LTB4R", | |
| "CD9", | |
| "ADGRE2", | |
| "DEFB103A", | |
| "FKBP5", | |
| "CR2", | |
| "CD53", | |
| "CXCR2", | |
| "CIITA", | |
| "FYN", | |
| "BST2", | |
| "CD86", | |
| "PTGS2", | |
| "CCL3", | |
| "DEFB103B", | |
| "PSMB5", | |
| "CCL20", | |
| "CTNNB1", | |
| "PTAFR", | |
| "ATG16L1", | |
| "FCAR", | |
| "CCND3", | |
| "IL4R", | |
| "CCL5", | |
| "SLC2A1", | |
| "S1PR1", | |
| "NFATC2", | |
| "KLRC3", | |
| "CARD9", | |
| "CCR8", | |
| "CRADD", | |
| "MBP", | |
| "IL7", | |
| "POLR1G", | |
| "IGF2R", | |
| "IKZF1", | |
| "NT5E", | |
| "IL6", | |
| "BCL3", | |
| "AIRE", | |
| "MAPKAPK2", | |
| "CD46", | |
| "ATG12", | |
| "CD14", | |
| "IRGM", | |
| "IRF7", | |
| "FN1", | |
| "ABL1", | |
| "ACKR4", | |
| "MALT1", | |
| "TNFSF11", | |
| "CCL13", | |
| "LTB4R2", | |
| "CXCL11", | |
| "IL17A", | |
| "CCL22", | |
| "CD80", | |
| "FAS", | |
| "CCRL2", | |
| "LCP2", | |
| "CD19", | |
| "ITGA5", | |
| "CFI", | |
| "CCL2", | |
| "FOXP3", | |
| "CD79B", | |
| "KLRA1P", | |
| "CFH", | |
| "FCER1A", | |
| "MUC1", | |
| "CD160", | |
| "NOTCH2", | |
| "HLA-DRB3", | |
| "DEFB1", | |
| "IL22", | |
| "RAG2", | |
| "CD36", | |
| "LIF", | |
| "SPP1", | |
| "SELPLG", | |
| "FCGR2B", | |
| "NLRP3", | |
| "CCL19", | |
| "NOD2", | |
| "PSMC2", | |
| "SELE", | |
| "MAP4K4", | |
| "IL1RAP", | |
| "PDCD1", | |
| "EGR1", | |
| "CFD", | |
| "IL13RA1", | |
| "IL10", | |
| "ATG7", | |
| "IL32", | |
| "CD7", | |
| "MX1", | |
| "GP1BB", | |
| "IL4", | |
| "CD274", | |
| "ZBTB16", | |
| "IL16", | |
| "CUL9", | |
| "TNFSF15", | |
| "CFB", | |
| "IL1B", | |
| "GZMK", | |
| "IL21", | |
| "IL21R", | |
| "CD1D", | |
| "POU2F2", | |
| "EDNRB", | |
| "STAT4", | |
| "SLAMF6", | |
| "CSF2", | |
| "BTLA", | |
| "IL7R", | |
| "CD48", | |
| "MSR1", | |
| "TLR4", | |
| "IFI16", | |
| "ITLN2", | |
| "TOLLIP", | |
| "PDCD2", | |
| "AICDA", | |
| "CD4", | |
| "IL1RN", | |
| "IL26", | |
| "ATG10", | |
| "KCNJ2", | |
| "SLAMF1", | |
| "KLRG1", | |
| "ITGA2B", | |
| "TNFSF8", | |
| "CXCL8", | |
| "CD70", | |
| "IRF5", | |
| "IRF3", | |
| "TNFSF13B", | |
| "CX3CR1", | |
| "IL3", | |
| "TIRAP", | |
| "ITGB1", | |
| "BCL10", | |
| "TCF7", | |
| "CLU", | |
| "TNFRSF17", | |
| "IFNA2", | |
| "CLEC5A", | |
| "IRAK4", | |
| "PDCD1LG2", | |
| "ITGA4", | |
| "BLNK", | |
| "CXCL1", | |
| "CASP8", | |
| "IRAK1", | |
| "CLEC6A", | |
| "PAX5", | |
| "IFI35", | |
| "RAG1", | |
| "CCL4", | |
| "MAPK11", | |
| "CCL16", | |
| "IL2RA", | |
| "TGFBI", | |
| "TNFRSF10C", | |
| "C5", | |
| "TAPBP", | |
| "HLA-DMB", | |
| "CD163", | |
| "TRAF1", | |
| "MME", | |
| "CD1A", | |
| "CCR10", | |
| "UBE2L3", | |
| "MIF", | |
| "IRF4", | |
| "HLA-C", | |
| "PRKCD", | |
| "CCR6", | |
| "B2M", | |
| "CTSC", | |
| "CCR2", | |
| "BAX", | |
| "LCK", | |
| "TLR1", | |
| "CD8B", | |
| "CD58", | |
| "PTPN2", | |
| "CD164", | |
| "CCR1", | |
| "IL12B", | |
| "TCF4", | |
| "CCL26", | |
| "TAGAP", | |
| "CD96", | |
| "HAVCR2", | |
| "IL6R", | |
| "PSMB7", | |
| "IFNL1", | |
| "CLEC4E", | |
| "NCAM1", | |
| "ITGAL", | |
| "MS4A1", | |
| "C1QA", | |
| "PLA2G2E", | |
| "TRAF4", | |
| "CCL23", | |
| "IL10RA", | |
| "CD99", | |
| "MYD88", | |
| "IKBKE", | |
| "IL15", | |
| "ITGB2", | |
| "CASP10", | |
| "NFATC1", | |
| "BST1", | |
| "CD28", | |
| "STAT1", | |
| "CXCR6", | |
| "KLRG2", | |
| "ADA", | |
| "CSF2RB", | |
| "ENTPD1", | |
| "ICAM3", | |
| "STAT3", | |
| "CDKN1A", | |
| "TLR9", | |
| "CSF1", | |
| "RELB", | |
| "ICAM1", | |
| "TNFSF12", | |
| "PLAU", | |
| "ARHGDIB", | |
| "CD8A", | |
| "STAT5A", | |
| "TLR2", | |
| "CEACAM6", | |
| "CXCL12", | |
| "CD74", | |
| "CXCL2", | |
| "PTGER4", | |
| "IL27", | |
| "SMAD5", | |
| "IL2RG", | |
| "IFNAR1", | |
| "PML", | |
| "HAMP", | |
| "CCL11", | |
| "PDGFB", | |
| "SYK", | |
| "KLRB1", | |
| "HLA-DPA1", | |
| "IFIH1", | |
| "PRDM1", | |
| "IFNB1", | |
| "MRC1", | |
| "ITGAM", | |
| "CD276", | |
| "TGFBR1", | |
| "LILRB2", | |
| "IL6ST", | |
| "TNFRSF9", | |
| "TLR5", | |
| "C6", | |
| "CD81", | |
| "CD40", | |
| "KLRC1", | |
| "CEBPB", | |
| "CD55", | |
| "PDGFRB", | |
| "XCL1", | |
| "VCAM1", | |
| "IKBKB", | |
| "TLR8", | |
| "IL17F", | |
| "S100A8", | |
| "IL5", | |
| "CD83", | |
| "NOTCH1", | |
| "CD34", | |
| "NFKBIZ", | |
| "IL2RB", | |
| "KIR3DL1", | |
| "IL20", | |
| "FCGRT", | |
| "PSMD7", | |
| "CX3CL1", | |
| "PLAUR", | |
| "ARG2", | |
| "LAIR1", | |
| "LAG3", | |
| "NCF4", | |
| "C1QBP", | |
| "C7", | |
| "MR1", | |
| "PRF1", | |
| "LITAF", | |
| "CCR5", | |
| "TRAF6", | |
| "HLA-A", | |
| "IL1RL2", | |
| "JAK3", | |
| "FCGR2A", | |
| "KIT", | |
| "KLRF1", | |
| "NFKB2", | |
| "RTRAF", | |
| "CD6", | |
| "LILRA6", | |
| "THY1", | |
| "IL11RA", | |
| "C1S", | |
| "GPI", | |
| "GATA3", | |
| "SERPING1", | |
| "ELP1", | |
| "CD3D", | |
| "LILRA1", | |
| "TNFRSF11A", | |
| "NOD1", | |
| "XCR1", | |
| "TNFRSF1B", | |
| "IL18", | |
| "CMKLR1", | |
| "HLA-DOB", | |
| "HLA-DPB1", | |
| "IRAK3", | |
| "CD2", | |
| "GBP5", | |
| "TBK1", | |
| "TGFBR2", | |
| "SOCS3", | |
| "GBP1", | |
| "BCL6", | |
| "IL23R", | |
| "CR1", | |
| "TNFSF4", | |
| "ARG1", | |
| "LTA", | |
| "TFRC", | |
| "CCL18", | |
| "CYBB", | |
| "CXCL13", | |
| "CCL7", | |
| "CSF3R", | |
| "AHR", | |
| "ICOS", | |
| "ITGA6", | |
| "CASP2", | |
| "LY96", | |
| "C9", | |
| "TYK2", | |
| "KIR3DL3", | |
| "IFNL2", | |
| "STAT6", | |
| "LAMP3", | |
| "BID", | |
| "TNF", | |
| "TNFRSF8", | |
| "LILRB1", | |
| "IL12A", | |
| "ITGAE", | |
| "PSMB9", | |
| "TNFRSF13B", | |
| "IRF8", | |
| "NOS2", | |
| "CD247", | |
| "CDH5", | |
| "IFNGR1", | |
| "CD244", | |
| "HLA-B", | |
| "CHUK", | |
| "ILF3", | |
| "IFIT2", | |
| "ICAM5", | |
| "SOCS1", | |
| "MAPK1", | |
| "TNFRSF14", | |
| "IL18RAP", | |
| "DUSP4", | |
| "CEACAM8", | |
| "CASP3", | |
| "IL9", | |
| "IKZF2", | |
| "TAP2", | |
| "LILRA3", | |
| "MAF", | |
| "ICOSLG", | |
| "PLAAT4", | |
| "HLA-DRB1", | |
| "TIGIT", | |
| "RUNX1", | |
| "PIGR", | |
| "IKZF3", | |
| "ATM", | |
| "CD79A", | |
| "LGALS3", | |
| "CLEC7A", | |
| "PTPN6", | |
| "CD27", | |
| "CD5", | |
| "MASP1", | |
| "HLA-DMA", | |
| "CD24", | |
| "IRF1", | |
| "IDO1", | |
| "NCR1", | |
| "CSF1R", | |
| "TRAF3", | |
| "PPARG", | |
| "IL13", | |
| "LTF", | |
| "TNFSF10", | |
| "XBP1", | |
| "JAK1", | |
| "STAT5B", | |
| "LTBR", | |
| "CD44", | |
| "CASP1", | |
| "PTPN22", | |
| "LEF1", | |
| "CFP", | |
| "RORC", | |
| "HLA-DQB1", | |
| "ITGAX", | |
| "RAF1", | |
| "GZMB", | |
| "KLRC4", | |
| "LILRB3", | |
| "TRAF2", | |
| "PTK2", | |
| "MASP2", | |
| "KLRC2", | |
| "SLAMF7", | |
| "CTSG", | |
| "GFI1", | |
| "CD82", | |
| "IL1R2", | |
| "CXCL10", | |
| "DPP4", | |
| "TAL1", | |
| "ZEB1", | |
| "IL18R1", | |
| "MBL2", | |
| "VTN", | |
| "TICAM1", | |
| "LILRA2", | |
| "NFATC3", | |
| "HLA-DRA", | |
| "IL19", | |
| "ICAM4", | |
| "IFNG", | |
| "LILRA5", | |
| "CISH", | |
| "CXCR4", | |
| "KLRD1", | |
| "CTSS", | |
| "IL1A", | |
| "TAP1", | |
| "LILRA4", | |
| "SH2D1A", | |
| "PPBP", | |
| "GNLY", | |
| "CLEC4A", | |
| "ABCB1", | |
| "GZMA", | |
| "CEACAM1", | |
| "CXCL9", | |
| "KIR3DL2", | |
| "IL17B", | |
| "CD209", | |
| "RELA", | |
| "C8A", | |
| "EOMES", | |
| "LILRB4", | |
| "CD3E", | |
| "IL12RB1", | |
| "ICAM2", | |
| "SRC", | |
| "C2", | |
| "CCL24", | |
| "IL1RL1", | |
| "CD22", | |
| "PSMB10", | |
| "SMAD3", | |
| "ITLN1", | |
| "IL22RA2", | |
| "IFITM1", | |
| "STAT2", | |
| "MAP4K2", | |
| "CXCR1", | |
| "MAP4K1", | |
| "TLR7", | |
| "GPR183", | |
| "S100A9", | |
| "JAK2", | |
| "KLRK1", | |
| "SELL", | |
| "ZAP70", | |
| "NFKBIA", | |
| "PLA2G2A", | |
| "NFIL3", | |
| "PSMB8", | |
| "FCER1G", | |
| "IL23A", | |
| "PECAM1", | |
| "TNFAIP3", | |
| "C8B", | |
| "IKBKG", | |
| "IL2", | |
| "CCR7", | |
| "TNFAIP6", | |
| "SKI", | |
| "TNFRSF13C", | |
| "MARCO", | |
| "TGFB1", | |
| "MCL1", | |
| "ETS1", | |
| "SIGIRR", | |
| "IFNAR2", | |
| "KLRF2", | |
| "TNFRSF4", | |
| "PYCARD", | |
| "NFKB1", | |
| "C8G", | |
| "CAMP", | |
| "STING1", | |
| "TRAF5", | |
| "TBX21" | |
| ], | |
| "Coefficient": [ | |
| 0.11545340883266886, | |
| -0.086759966669568, | |
| 0.08340420888060858, | |
| 0.07715063935946884, | |
| 0.0765634352931088, | |
| 0.07561465344249187, | |
| -0.07426181242283093, | |
| -0.07285148120062092, | |
| 0.07021828247335637, | |
| 0.06960736485668415, | |
| 0.06957025569822184, | |
| 0.06656473420195676, | |
| -0.06567668225171501, | |
| -0.06461722937021885, | |
| 0.06450444485646409, | |
| -0.0628665437581968, | |
| 0.06270403606988201, | |
| -0.061786109416074014, | |
| -0.059778670390642115, | |
| -0.05932081086534243, | |
| 0.05894700095255609, | |
| 0.057729010785393435, | |
| 0.05759552208669627, | |
| -0.05639255837765731, | |
| 0.056382977545182913, | |
| -0.05621640388505176, | |
| -0.05537147812451394, | |
| -0.05466230189490238, | |
| 0.05344336108063797, | |
| 0.0533994318205374, | |
| 0.053372481254930354, | |
| 0.05286255056747683, | |
| -0.052547283974159434, | |
| -0.05251447738840465, | |
| 0.052163567239562975, | |
| -0.05181045331481278, | |
| 0.05180598425958666, | |
| 0.05114770625215525, | |
| 0.05099344712049278, | |
| 0.05089839152667461, | |
| 0.05015538806207789, | |
| 0.04972867117842216, | |
| -0.049562729345950726, | |
| 0.049372523024491674, | |
| -0.047163369399194105, | |
| 0.047068275121433426, | |
| 0.04646986261978511, | |
| -0.04618816471347503, | |
| -0.04602732231031706, | |
| 0.045001628899819145, | |
| -0.04448207292127041, | |
| -0.0444715628948276, | |
| 0.04446976530752887, | |
| 0.0444034921031834, | |
| 0.04419461601184578, | |
| 0.044179779819608495, | |
| -0.04412422530573074, | |
| -0.04344765220141993, | |
| 0.04318000611962582, | |
| -0.042813005858479074, | |
| 0.04224413936367063, | |
| -0.04214008063088229, | |
| -0.04191156995370039, | |
| -0.041895003848939814, | |
| 0.04176929151002131, | |
| -0.04120189559422319, | |
| -0.0410318162558579, | |
| 0.040065703274787035, | |
| 0.0398148893350904, | |
| -0.03977221350800035, | |
| -0.03958410282680791, | |
| 0.03910020489777414, | |
| -0.0390878442901982, | |
| 0.03897099138338496, | |
| 0.038955427136146435, | |
| 0.03892231043983046, | |
| 0.03801646582464358, | |
| 0.03780579039132278, | |
| -0.037784657913212366, | |
| 0.037699931911622415, | |
| -0.03769663592347973, | |
| -0.037486833461389535, | |
| -0.03747787856170612, | |
| 0.03731536265467772, | |
| -0.03711763825436172, | |
| -0.036960317551165384, | |
| 0.03682674556911436, | |
| -0.036483010385031905, | |
| 0.036410858367162305, | |
| 0.03638131391329091, | |
| -0.03633837044432888, | |
| 0.03613231672163743, | |
| 0.03611100704712703, | |
| 0.0359672862053622, | |
| 0.0356908987347372, | |
| -0.03521783732977634, | |
| -0.03501180307250681, | |
| 0.03488948035851056, | |
| 0.03463898107998772, | |
| -0.03438248778725731, | |
| -0.03419202613785016, | |
| 0.03394603925489537, | |
| 0.03379927053147696, | |
| -0.03363122604223661, | |
| -0.033527625915192635, | |
| 0.03318184749420439, | |
| -0.03295310947254472, | |
| -0.03268257195429434, | |
| 0.032560680134943364, | |
| 0.0325193647875964, | |
| 0.032326233504143716, | |
| -0.03229546738558885, | |
| -0.032276438933055575, | |
| 0.03226562002288423, | |
| -0.032190649057230104, | |
| -0.032088032288935864, | |
| -0.031988298525106436, | |
| 0.03155215792378619, | |
| -0.03151678588027256, | |
| 0.03095182890377953, | |
| 0.030116798925074625, | |
| 0.030105712925080866, | |
| 0.03002786163263579, | |
| -0.02993950320482163, | |
| 0.02965246307485905, | |
| 0.029311343474810382, | |
| -0.02928078918562208, | |
| 0.029208029484516052, | |
| -0.028857969973493134, | |
| 0.02882389473874926, | |
| -0.0288046921471616, | |
| -0.02879498068082626, | |
| 0.028748294480286953, | |
| 0.02865049705475178, | |
| 0.02852890194402672, | |
| -0.028435811993825454, | |
| -0.028367942863408005, | |
| -0.02808034640026065, | |
| -0.02806024507327019, | |
| 0.028055665826727444, | |
| 0.027936977360251393, | |
| -0.02791615293351699, | |
| 0.027766563228033714, | |
| -0.027264037168872914, | |
| 0.027158659706836345, | |
| 0.027017645592848683, | |
| -0.02671985221199339, | |
| -0.026707440979772446, | |
| -0.02666240300711862, | |
| -0.026642657746852653, | |
| -0.026418689956603503, | |
| 0.026395018949221985, | |
| -0.026391382490103883, | |
| 0.026088622030521855, | |
| -0.026053774891108272, | |
| -0.02603640870503908, | |
| -0.026033424377174152, | |
| 0.02582497313659735, | |
| -0.025725514577745603, | |
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| ], | |
| "Absolute Coefficient": [ | |
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| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 60.8695652173913, | |
| "precision": 35.24025974025974, | |
| "recall": 40.666666666666664, | |
| "f1": 37.11010558069381 | |
| }, | |
| "selection": { | |
| "precision": 9.44741532976827, | |
| "recall": 100.0, | |
| "f1": 17.263843648208468, | |
| "jaccard": 9.44741532976827 | |
| } | |
| } | |
| } |