| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BATF3", | |
| "BCL2L11", | |
| "C1R", | |
| "BTK", | |
| "BCAP31", | |
| "C4BPA", | |
| "B3GAT1", | |
| "APP", | |
| "C1QB", | |
| "DEFB4A", | |
| "CD40LG", | |
| "CCL8", | |
| "IRAK2", | |
| "CXCR3", | |
| "HLA-DQA1", | |
| "BCL2", | |
| "ADGRE2", | |
| "LILRB5", | |
| "MAPK14", | |
| "CCL15", | |
| "EBI3", | |
| "CD59", | |
| "TLR3", | |
| "TP53", | |
| "C3", | |
| "FADD", | |
| "EGR2", | |
| "HRAS", | |
| "IL1R1", | |
| "FKBP5", | |
| "CD9", | |
| "HFE", | |
| "CR2", | |
| "CD86", | |
| "CXCR2", | |
| "LTB4R", | |
| "CIITA", | |
| "BATF", | |
| "BST2", | |
| "PTGS2", | |
| "DEFB103A", | |
| "CD53", | |
| "DEFB103B", | |
| "CCND3", | |
| "FYN", | |
| "PTAFR", | |
| "CTNNB1", | |
| "PSMB5", | |
| "BCL3", | |
| "CCL20", | |
| "CCL3", | |
| "CCL5", | |
| "IL4R", | |
| "KLRC3", | |
| "IL7", | |
| "CRADD", | |
| "S1PR1", | |
| "POLR1G", | |
| "NFATC2", | |
| "SLC2A1", | |
| "CARD9", | |
| "IKZF1", | |
| "MBP", | |
| "ATG16L1", | |
| "CD160", | |
| "FCAR", | |
| "CCR8", | |
| "NT5E", | |
| "CCL22", | |
| "CD14", | |
| "MALT1", | |
| "IGF2R", | |
| "CFI", | |
| "MAPKAPK2", | |
| "ACKR4", | |
| "CCL13", | |
| "FOXP3", | |
| "IRGM", | |
| "FAS", | |
| "IL6", | |
| "IRF7", | |
| "FN1", | |
| "LTB4R2", | |
| "IL17A", | |
| "CD46", | |
| "CCL2", | |
| "TNFSF11", | |
| "CCRL2", | |
| "CD19", | |
| "ATG10", | |
| "CXCL11", | |
| "CD79B", | |
| "NOTCH2", | |
| "LCP2", | |
| "CFH", | |
| "CFD", | |
| "AIRE", | |
| "KLRA1P", | |
| "FCGR2B", | |
| "MUC1", | |
| "ATG12", | |
| "RAG2", | |
| "ITGA5", | |
| "IL22", | |
| "EGR1", | |
| "MAP4K4", | |
| "FCER1A", | |
| "CD80", | |
| "NOD2", | |
| "CD36", | |
| "NLRP3", | |
| "HLA-DRB3", | |
| "LIF", | |
| "PSMC2", | |
| "SELPLG", | |
| "CCL19", | |
| "SPP1", | |
| "DEFB1", | |
| "BLNK", | |
| "ABL1", | |
| "PDCD1", | |
| "GZMK", | |
| "MX1", | |
| "IL4", | |
| "SELE", | |
| "ZBTB16", | |
| "IL21", | |
| "IL1RAP", | |
| "CUL9", | |
| "IL13RA1", | |
| "IL1B", | |
| "IL16", | |
| "IL21R", | |
| "ATG7", | |
| "KCNJ2", | |
| "IL10", | |
| "AICDA", | |
| "EDNRB", | |
| "CD4", | |
| "IL32", | |
| "TNFSF15", | |
| "CD1D", | |
| "ITLN2", | |
| "CCR6", | |
| "IL2RA", | |
| "CSF2", | |
| "CFB", | |
| "TLR4", | |
| "STAT4", | |
| "ITGB1", | |
| "HLA-C", | |
| "CD1A", | |
| "TNFSF8", | |
| "PDCD2", | |
| "POU2F2", | |
| "CD7", | |
| "BAX", | |
| "MSR1", | |
| "CD274", | |
| "CLEC6A", | |
| "IL26", | |
| "CD8B", | |
| "SLAMF6", | |
| "BCL10", | |
| "TIRAP", | |
| "IFI16", | |
| "BTLA", | |
| "CD96", | |
| "GP1BB", | |
| "TCF7", | |
| "ITGA4", | |
| "CD70", | |
| "ITGA2B", | |
| "TNFRSF17", | |
| "IL3", | |
| "TNFSF13B", | |
| "IRF5", | |
| "CCL16", | |
| "IFI35", | |
| "CLU", | |
| "IL7R", | |
| "CCR2", | |
| "IL1RN", | |
| "IRF3", | |
| "PDCD1LG2", | |
| "CCR1", | |
| "TGFBI", | |
| "TOLLIP", | |
| "RAG1", | |
| "SLAMF1", | |
| "TAPBP", | |
| "CCL4", | |
| "CXCL1", | |
| "IL6R", | |
| "CLEC5A", | |
| "IRAK1", | |
| "CXCL8", | |
| "TRAF1", | |
| "CTSC", | |
| "IFNA2", | |
| "KLRG1", | |
| "MAPK11", | |
| "MME", | |
| "KLRG2", | |
| "PAX5", | |
| "TNFRSF10C", | |
| "ARHGDIB", | |
| "PRKCD", | |
| "ENTPD1", | |
| "UBE2L3", | |
| "PTPN2", | |
| "TLR1", | |
| "IRAK4", | |
| "TAGAP", | |
| "IRF4", | |
| "MS4A1", | |
| "CDKN1A", | |
| "CCR10", | |
| "CD48", | |
| "MYD88", | |
| "IL12B", | |
| "C5", | |
| "NCAM1", | |
| "PSMB7", | |
| "LCK", | |
| "B2M", | |
| "CX3CR1", | |
| "CD163", | |
| "HLA-DMB", | |
| "TCF4", | |
| "CASP8", | |
| "ICAM3", | |
| "ADA", | |
| "BST1", | |
| "MIF", | |
| "IL15", | |
| "IKBKE", | |
| "PML", | |
| "C1QA", | |
| "CXCR6", | |
| "CASP10", | |
| "TLR9", | |
| "PLA2G2E", | |
| "CCL26", | |
| "HAVCR2", | |
| "CD58", | |
| "ITGAL", | |
| "IFNL1", | |
| "IL2RG", | |
| "ICAM1", | |
| "TLR2", | |
| "RELB", | |
| "TRAF4", | |
| "TNFSF12", | |
| "NFATC1", | |
| "CD276", | |
| "PLAU", | |
| "CSF1", | |
| "CEACAM6", | |
| "STAT1", | |
| "ITGB2", | |
| "CD164", | |
| "CXCL2", | |
| "CD99", | |
| "STAT3", | |
| "CXCL12", | |
| "MRC1", | |
| "CCL18", | |
| "CCL23", | |
| "CLEC4E", | |
| "NOTCH1", | |
| "HLA-DPA1", | |
| "CD81", | |
| "CD40", | |
| "IL10RA", | |
| "XCL1", | |
| "C1QBP", | |
| "KLRB1", | |
| "C6", | |
| "TGFBR1", | |
| "STAT5A", | |
| "IL27", | |
| "CSF2RB", | |
| "CR1", | |
| "SMAD5", | |
| "SYK", | |
| "ITGAM", | |
| "CD28", | |
| "CD8A", | |
| "KIR3DL1", | |
| "CD34", | |
| "VCAM1", | |
| "IFNAR1", | |
| "GATA3", | |
| "PTGER4", | |
| "CEBPB", | |
| "TNFRSF9", | |
| "IFNB1", | |
| "TLR5", | |
| "IL6ST", | |
| "CD2", | |
| "PRDM1", | |
| "LILRB2", | |
| "C7", | |
| "PDGFB", | |
| "NFKBIZ", | |
| "LAIR1", | |
| "IL17F", | |
| "LITAF", | |
| "C1S", | |
| "TNFRSF1B", | |
| "CD55", | |
| "S100A8", | |
| "IL2RB", | |
| "FCGRT", | |
| "IFIH1", | |
| "TRAF6", | |
| "IL20", | |
| "IL18", | |
| "PSMD7", | |
| "KLRC1", | |
| "ARG1", | |
| "GBP5", | |
| "CD74", | |
| "HLA-A", | |
| "PLAUR", | |
| "XCR1", | |
| "LAG3", | |
| "CCL11", | |
| "HAMP", | |
| "TNFRSF11A", | |
| "TLR8", | |
| "PDGFRB", | |
| "ARG2", | |
| "IRAK3", | |
| "GPI", | |
| "THY1", | |
| "NCF4", | |
| "JAK3", | |
| "RTRAF", | |
| "SOCS3", | |
| "IFNL2", | |
| "FCGR2A", | |
| "LILRA1", | |
| "CASP2", | |
| "CD83", | |
| "HLA-B", | |
| "IL11RA", | |
| "IKBKB", | |
| "HLA-DPB1", | |
| "BCL6", | |
| "TFRC", | |
| "TGFBR2", | |
| "MR1", | |
| "ITGA6", | |
| "KIT", | |
| "SERPING1", | |
| "KIR3DL3", | |
| "NFKB2", | |
| "PRF1", | |
| "STAT6", | |
| "IL5", | |
| "TNFSF4", | |
| "CD6", | |
| "TNFRSF13B", | |
| "IFNGR1", | |
| "CLEC7A", | |
| "LILRA6", | |
| "LTA", | |
| "IL1RL2", | |
| "MAF", | |
| "IL23R", | |
| "NOD1", | |
| "TBK1", | |
| "IL12A", | |
| "CSF3R", | |
| "NOS2", | |
| "CD3D", | |
| "ELP1", | |
| "HLA-DOB", | |
| "IFIT2", | |
| "TYK2", | |
| "ITGAE", | |
| "CYBB", | |
| "LILRB1", | |
| "CCR5", | |
| "GBP1", | |
| "AHR", | |
| "CMKLR1", | |
| "C9", | |
| "ICOSLG", | |
| "SOCS1", | |
| "CX3CL1", | |
| "PIGR", | |
| "KLRF1", | |
| "HLA-DMA", | |
| "ICOS", | |
| "LY96", | |
| "PSMB9", | |
| "LAMP3", | |
| "CEACAM8", | |
| "ILF3", | |
| "CD244", | |
| "TNF", | |
| "PTPN6", | |
| "IRF8", | |
| "IRF1", | |
| "CEACAM1", | |
| "CD82", | |
| "CD5", | |
| "BID", | |
| "CDH5", | |
| "MAPK1", | |
| "CCL7", | |
| "PLAAT4", | |
| "ICAM5", | |
| "TNFRSF8", | |
| "IKZF3", | |
| "CFP", | |
| "MASP1", | |
| "TIGIT", | |
| "RUNX1", | |
| "ICAM2", | |
| "LILRA3", | |
| "CD79A", | |
| "NCR1", | |
| "TNFRSF14", | |
| "TAP2", | |
| "IDO1", | |
| "CASP3", | |
| "CD44", | |
| "PTPN22", | |
| "CHUK", | |
| "IKZF2", | |
| "RORC", | |
| "PTK2", | |
| "CD27", | |
| "LTBR", | |
| "CXCL13", | |
| "GFI1", | |
| "IL18RAP", | |
| "DUSP4", | |
| "GZMB", | |
| "IL9", | |
| "HLA-DQB1", | |
| "IL13", | |
| "STAT5B", | |
| "C2", | |
| "LGALS3", | |
| "RAF1", | |
| "MASP2", | |
| "CD247", | |
| "CD24", | |
| "SLAMF7", | |
| "ABCB1", | |
| "TRAF2", | |
| "PPARG", | |
| "TNFSF10", | |
| "IL1R2", | |
| "LTF", | |
| "CISH", | |
| "XBP1", | |
| "HLA-DRB1", | |
| "TICAM1", | |
| "LEF1", | |
| "DPP4", | |
| "IL19", | |
| "CSF1R", | |
| "KLRC2", | |
| "CTSG", | |
| "LILRA5", | |
| "TRAF3", | |
| "IL18R1", | |
| "FCER1G", | |
| "ICAM4", | |
| "HLA-DRA", | |
| "ATM", | |
| "IL1A", | |
| "ITGAX", | |
| "KLRC4", | |
| "TAP1", | |
| "CLEC4A", | |
| "JAK1", | |
| "GNLY", | |
| "MBL2", | |
| "LILRB3", | |
| "CASP1", | |
| "LILRA2", | |
| "CXCL10", | |
| "IL12RB1", | |
| "ITLN1", | |
| "CXCR4", | |
| "CD22", | |
| "ZEB1", | |
| "NFATC3", | |
| "KLRD1", | |
| "SH2D1A", | |
| "C8A", | |
| "CD3E", | |
| "MARCO", | |
| "LILRA4", | |
| "KIR3DL2", | |
| "MAP4K2", | |
| "GZMA", | |
| "TNFAIP6", | |
| "CXCR1", | |
| "VTN", | |
| "TAL1", | |
| "SRC", | |
| "IKBKG", | |
| "GPR183", | |
| "RELA", | |
| "MCL1", | |
| "NFIL3", | |
| "SELL", | |
| "LILRB4", | |
| "CTSS", | |
| "S100A9", | |
| "TGFB1", | |
| "CD209", | |
| "IFNAR2", | |
| "CCR7", | |
| "EOMES", | |
| "SMAD3", | |
| "IFITM1", | |
| "KLRK1", | |
| "IL17B", | |
| "TBX21", | |
| "IL2", | |
| "JAK2", | |
| "PSMB10", | |
| "TNFRSF13C", | |
| "C8B", | |
| "PLA2G2A", | |
| "NFKB1", | |
| "PSMB8", | |
| "C8G", | |
| "STAT2", | |
| "MAP4K1", | |
| "IL22RA2", | |
| "PPBP", | |
| "CXCL9", | |
| "TNFRSF4", | |
| "TNFAIP3", | |
| "TRAF5", | |
| "PECAM1", | |
| "IFNG", | |
| "CCL24", | |
| "ETS1", | |
| "SKI", | |
| "ZAP70", | |
| "CAMP", | |
| "STING1", | |
| "IL1RL1", | |
| "NFKBIA", | |
| "SIGIRR", | |
| "TLR7", | |
| "IL23A", | |
| "PYCARD", | |
| "KLRF2" | |
| ], | |
| "Coefficient": [ | |
| 0.11593349760378022, | |
| -0.08902444332107762, | |
| 0.08091691210894186, | |
| 0.07668167000459082, | |
| -0.07581742929013773, | |
| 0.07431672562262875, | |
| -0.0740304349722961, | |
| 0.07257919320092836, | |
| 0.06817690301608052, | |
| 0.06754663257912967, | |
| -0.06697440948449204, | |
| 0.06586286315988672, | |
| -0.0652689313861902, | |
| -0.06447689822232833, | |
| 0.06433499607072984, | |
| 0.0629038447103067, | |
| 0.06261140209194233, | |
| -0.06223720670402955, | |
| -0.06150962130448277, | |
| -0.060442216038361654, | |
| 0.05977548270322913, | |
| 0.05835080205554876, | |
| -0.056857717254475755, | |
| 0.05680162688579825, | |
| -0.05602314929737757, | |
| 0.05601116939119595, | |
| -0.05560628813411803, | |
| -0.05481362751930846, | |
| 0.054617031972584086, | |
| 0.05435631579756797, | |
| -0.05417126687470663, | |
| -0.05392108795525891, | |
| -0.05357751752672325, | |
| 0.05297480316876968, | |
| -0.05284981404168121, | |
| 0.05259624978543704, | |
| 0.0524267929451732, | |
| 0.05228688429071715, | |
| 0.051099861034540436, | |
| 0.050332053553353316, | |
| 0.05031576704216455, | |
| 0.048878460728525516, | |
| 0.04848185635669603, | |
| 0.04823147678863348, | |
| 0.046123148025607616, | |
| 0.04580237870692568, | |
| 0.04554203756038423, | |
| -0.0453475211631671, | |
| 0.04532184754651135, | |
| -0.04503948129264331, | |
| -0.04503298553091863, | |
| -0.04489386640607669, | |
| 0.04485443746682627, | |
| 0.044731009663292035, | |
| 0.0438035739418841, | |
| -0.043538614133580976, | |
| -0.04350245657928282, | |
| -0.04349988940690887, | |
| 0.04339899264879226, | |
| -0.043379483530261984, | |
| 0.042876195887061604, | |
| -0.04248958124073684, | |
| -0.04239599904827677, | |
| -0.042068787187870126, | |
| -0.04150025932368595, | |
| 0.0412214978643104, | |
| -0.041119409566089254, | |
| 0.04098669023541362, | |
| 0.04058154402717685, | |
| 0.040279542931632675, | |
| 0.04027754348180495, | |
| -0.04022429696955051, | |
| -0.03994223506656705, | |
| 0.03954050205954177, | |
| 0.0394719180915318, | |
| 0.03901398025978737, | |
| -0.03883383822012147, | |
| -0.03882129037533123, | |
| 0.038501746612662605, | |
| 0.03835329571236541, | |
| 0.03826831753155028, | |
| 0.037833349726787556, | |
| 0.03760591331555461, | |
| 0.03710149485014164, | |
| -0.037083659358536664, | |
| -0.036437220860086474, | |
| 0.03636244426243808, | |
| -0.03635904168918728, | |
| 0.0356498905886336, | |
| 0.035449938564084654, | |
| 0.035447406020265235, | |
| -0.035358404458732215, | |
| -0.0352152527536782, | |
| 0.03468054422852331, | |
| -0.03461090877566838, | |
| 0.03448907864064171, | |
| 0.034143100167319126, | |
| -0.033878995495035404, | |
| 0.03379018966322187, | |
| -0.033534914411902914, | |
| -0.033388673745070326, | |
| 0.03335742892842936, | |
| -0.03331594418739948, | |
| 0.03308934108669271, | |
| 0.03295475186557044, | |
| 0.032801661478191524, | |
| 0.0327165596049127, | |
| -0.03265211676214367, | |
| -0.032599037293886926, | |
| -0.03259250345384989, | |
| -0.03256219979826365, | |
| -0.03200412738823635, | |
| -0.03199445751652058, | |
| 0.03197915906131458, | |
| -0.0319297668768924, | |
| 0.03189430099676336, | |
| 0.03142033581429395, | |
| 0.031290069751941235, | |
| -0.03126612969636622, | |
| 0.030584196531649403, | |
| -0.030336285235639547, | |
| 0.03026826807145595, | |
| -0.03025069848805359, | |
| 0.030030274536268123, | |
| 0.02980335988469922, | |
| -0.029796206044689955, | |
| -0.0297329541460324, | |
| -0.0292980716289972, | |
| -0.029291700457844603, | |
| 0.028985121341200445, | |
| 0.028904686470066585, | |
| -0.028726618919125726, | |
| 0.028636086749877582, | |
| 0.0285447707586412, | |
| 0.02851522410358318, | |
| -0.028365141743973112, | |
| -0.02835183913834133, | |
| -0.028272699254995877, | |
| 0.028106235361716927, | |
| -0.027883602122362634, | |
| 0.02779883241554797, | |
| 0.02760301875361424, | |
| 0.02755086035707068, | |
| -0.026959376727912855, | |
| -0.026930309702674127, | |
| -0.026900047164339868, | |
| 0.026862631207499436, | |
| -0.026862442688316973, | |
| -0.026860244754481923, | |
| -0.026737749929892963, | |
| 0.026564766341156006, | |
| -0.026515401165056168, | |
| -0.026452260891907806, | |
| 0.026387061354224257, | |
| -0.02638142617461828, | |
| -0.026351890538100286, | |
| -0.02634825401210634, | |
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| ], | |
| "Absolute Coefficient": [ | |
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| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 60.8695652173913, | |
| "precision": 35.04761904761905, | |
| "recall": 45.33333333333333, | |
| "f1": 38.595238095238095 | |
| }, | |
| "selection": { | |
| "precision": 9.450789406671758, | |
| "recall": 100.0, | |
| "f1": 17.26947622362387, | |
| "jaccard": 9.450789406671758 | |
| } | |
| } | |
| } |