{ | |
"significant_genes": { | |
"Variable": [ | |
"ATG5", | |
"BTK", | |
"DEFB4A", | |
"PTGS2", | |
"C3", | |
"C4BPA", | |
"IRAK2", | |
"BATF3", | |
"TP53", | |
"TLR3", | |
"CTNNB1", | |
"BCAP31", | |
"CD40LG", | |
"BCL2L11", | |
"CD59", | |
"LILRB5", | |
"CD46", | |
"IL1R1", | |
"POLR1G", | |
"B3GAT1", | |
"EBI3", | |
"HFE", | |
"DEFB103A", | |
"CCL8", | |
"S1PR1", | |
"BST2", | |
"CD86", | |
"C1QB", | |
"FADD", | |
"CCL15", | |
"IL7", | |
"CIITA", | |
"IKZF1", | |
"IRF7", | |
"SELPLG", | |
"MUC1", | |
"ATG16L1", | |
"KLRC3", | |
"TNFSF11", | |
"MAPK14", | |
"IRGM", | |
"NT5E", | |
"CRADD", | |
"LTB4R", | |
"MALT1", | |
"CLEC6A", | |
"CCL5", | |
"APP", | |
"PTAFR", | |
"HLA-DQA1", | |
"DEFB103B", | |
"C1R", | |
"PSMB5", | |
"CCRL2", | |
"LTB4R2", | |
"MAPKAPK2", | |
"SELE", | |
"CD160", | |
"SPP1", | |
"IL4R", | |
"TOLLIP", | |
"MBP", | |
"FAS", | |
"CD9", | |
"NFATC2", | |
"LIF", | |
"CD80", | |
"NOD2", | |
"IL6", | |
"CR2", | |
"POU2F2", | |
"CFI", | |
"ARG2", | |
"FOXP3", | |
"IL10RA", | |
"FYN", | |
"CD14", | |
"CCR8", | |
"CD19", | |
"CFD", | |
"FKBP5", | |
"HRAS", | |
"CCL20", | |
"CCL19", | |
"MSR1", | |
"SLC2A1", | |
"HLA-C", | |
"STAT4", | |
"FCAR", | |
"LCP2", | |
"ATG7", | |
"CXCR3", | |
"MX1", | |
"IL16", | |
"CD7", | |
"KLRA1P", | |
"CD53", | |
"IL1RAP", | |
"IKBKE", | |
"CCND3", | |
"CMKLR1", | |
"ADGRE2", | |
"NOTCH2", | |
"IL2RA", | |
"IL2RG", | |
"STAT3", | |
"ABL1", | |
"SLAMF6", | |
"EDNRB", | |
"CXCR2", | |
"IL6R", | |
"BLNK", | |
"IFI35", | |
"ZBTB16", | |
"IRF5", | |
"MS4A1", | |
"IL21", | |
"RAG1", | |
"MAP4K4", | |
"IL10", | |
"C1S", | |
"CD164", | |
"CD48", | |
"CCL13", | |
"EGR2", | |
"KLRB1", | |
"CLU", | |
"KLRG2", | |
"AIRE", | |
"CXCL11", | |
"IL3", | |
"IKBKB", | |
"XCL1", | |
"CLEC5A", | |
"ATG12", | |
"FCER1A", | |
"KCNJ2", | |
"DEFB1", | |
"PSMC2", | |
"KLRG1", | |
"TNFSF8", | |
"EGR1", | |
"IL15", | |
"CD55", | |
"TNFRSF17", | |
"IL12B", | |
"HLA-DRB3", | |
"GZMK", | |
"IL4", | |
"CCR10", | |
"IL11RA", | |
"CX3CL1", | |
"LITAF", | |
"ITGA5", | |
"CD28", | |
"TLR1", | |
"SLAMF1", | |
"CTSG", | |
"RAG2", | |
"CD8A", | |
"MRC1", | |
"IFNB1", | |
"IRF3", | |
"CDKN1A", | |
"FN1", | |
"TNFSF13B", | |
"C6", | |
"TAPBP", | |
"TRAF1", | |
"IL32", | |
"TRAF6", | |
"BCL3", | |
"PTPN2", | |
"TLR8", | |
"C5", | |
"CLEC4E", | |
"NOTCH1", | |
"CASP10", | |
"PRKCD", | |
"ICAM1", | |
"CXCL1", | |
"CCL16", | |
"TGFBI", | |
"IL23R", | |
"IL26", | |
"FCGR2B", | |
"BCL2", | |
"CXCR6", | |
"LCK", | |
"HLA-DMB", | |
"GP1BB", | |
"CD163", | |
"PLA2G2E", | |
"BTLA", | |
"PPARG", | |
"CD4", | |
"NCAM1", | |
"IL27", | |
"PDCD2", | |
"CD1A", | |
"NLRP3", | |
"CD276", | |
"PML", | |
"TGFBR1", | |
"CD99", | |
"ITGB1", | |
"GNLY", | |
"TNFSF15", | |
"IFI16", | |
"RELB", | |
"MME", | |
"C1QA", | |
"CFB", | |
"IL17A", | |
"CXCL12", | |
"IL1RN", | |
"CD274", | |
"TNFRSF13B", | |
"CD74", | |
"C7", | |
"TAP2", | |
"CCL23", | |
"IFIT2", | |
"ITGAE", | |
"PDCD1LG2", | |
"HAMP", | |
"IGF2R", | |
"MIF", | |
"PSMB7", | |
"IKZF2", | |
"CCL22", | |
"SERPING1", | |
"CCL2", | |
"IL13RA1", | |
"PSMB8", | |
"ARG1", | |
"S100A8", | |
"BST1", | |
"ICAM3", | |
"ITGAX", | |
"TLR4", | |
"CD79B", | |
"KIR3DL2", | |
"CCL3", | |
"PTPN6", | |
"IRAK4", | |
"PSMD7", | |
"HAVCR2", | |
"TCF7", | |
"CD6", | |
"B2M", | |
"CD83", | |
"CARD9", | |
"TNFSF10", | |
"KLRC2", | |
"CD247", | |
"IRF4", | |
"ENTPD1", | |
"IL1A", | |
"ARHGDIB", | |
"CSF2RB", | |
"PDCD1", | |
"CCL11", | |
"BID", | |
"IL20", | |
"CD82", | |
"TIGIT", | |
"CSF1R", | |
"CD27", | |
"BATF", | |
"STAT1", | |
"IFNGR1", | |
"LILRB3", | |
"MAPK11", | |
"CCL4", | |
"ITLN2", | |
"NOS2", | |
"PLAUR", | |
"LAG3", | |
"MASP2", | |
"TAGAP", | |
"IRAK1", | |
"TLR2", | |
"ATG10", | |
"CD8B", | |
"C8G", | |
"HLA-DPA1", | |
"CFH", | |
"TFRC", | |
"PLA2G2A", | |
"CD1D", | |
"MYD88", | |
"TIRAP", | |
"CD58", | |
"LAIR1", | |
"IL7R", | |
"AICDA", | |
"THY1", | |
"ACKR4", | |
"IL12RB1", | |
"PRDM1", | |
"SYK", | |
"IL22", | |
"NFATC1", | |
"PRF1", | |
"TAP1", | |
"MAPK1", | |
"IL21R", | |
"CUL9", | |
"TNFSF12", | |
"IFIH1", | |
"IRF8", | |
"CX3CR1", | |
"CCL26", | |
"CCL18", | |
"TNFRSF9", | |
"CCL7", | |
"IL2RB", | |
"MAF", | |
"CD244", | |
"KIR3DL1", | |
"HLA-B", | |
"CCR1", | |
"ITGB2", | |
"STAT5B", | |
"MR1", | |
"IL1RL2", | |
"IL17B", | |
"XCR1", | |
"LEF1", | |
"GBP1", | |
"IFNL1", | |
"IL1R2", | |
"CXCR1", | |
"PLAAT4", | |
"ICAM4", | |
"IDO1", | |
"CD2", | |
"NCF4", | |
"NFKB2", | |
"IL18", | |
"IL22RA2", | |
"LILRA4", | |
"CD70", | |
"ICAM2", | |
"MAP4K1", | |
"BAX", | |
"LTA", | |
"UBE2L3", | |
"CD5", | |
"CD40", | |
"IL6ST", | |
"ITGA4", | |
"IL12A", | |
"CASP8", | |
"PAX5", | |
"NCR1", | |
"PIGR", | |
"JAK3", | |
"IRAK3", | |
"SELL", | |
"LILRA3", | |
"ICOS", | |
"CCR2", | |
"TNFRSF4", | |
"IL23A", | |
"CXCL9", | |
"NFATC3", | |
"TNF", | |
"CD34", | |
"TRAF3", | |
"C9", | |
"SLAMF7", | |
"CXCL8", | |
"STAT5A", | |
"PYCARD", | |
"TRAF2", | |
"TLR9", | |
"LY96", | |
"IL13", | |
"CEACAM6", | |
"CXCL10", | |
"CEBPB", | |
"ZAP70", | |
"ITGA2B", | |
"IKBKG", | |
"JAK2", | |
"ELP1", | |
"IL18RAP", | |
"RAF1", | |
"CLEC7A", | |
"DUSP4", | |
"IFNA2", | |
"LILRB1", | |
"NFKBIZ", | |
"IFNAR2", | |
"HLA-DRA", | |
"TCF4", | |
"CHUK", | |
"CD81", | |
"IKZF3", | |
"LTBR", | |
"CXCR4", | |
"LILRA5", | |
"TLR5", | |
"KLRF2", | |
"CTSC", | |
"CCR6", | |
"STING1", | |
"TLR7", | |
"TNFRSF10C", | |
"KIR3DL3", | |
"JAK1", | |
"CSF1", | |
"ADA", | |
"TBK1", | |
"TNFRSF14", | |
"TRAF4", | |
"TNFRSF1B", | |
"CDH5", | |
"CAMP", | |
"IL1B", | |
"CD96", | |
"PDGFB", | |
"CASP1", | |
"HLA-DRB1", | |
"CFP", | |
"NOD1", | |
"KLRF1", | |
"GFI1", | |
"SH2D1A", | |
"KIT", | |
"PTPN22", | |
"CD3D", | |
"ITLN1", | |
"CD22", | |
"CD36", | |
"CEACAM8", | |
"LILRA2", | |
"ITGA6", | |
"GZMB", | |
"KLRC1", | |
"AHR", | |
"SMAD3", | |
"ICAM5", | |
"GPI", | |
"ITGAL", | |
"CD209", | |
"TNFRSF11A", | |
"HLA-DQB1", | |
"SIGIRR", | |
"LILRB4", | |
"RELA", | |
"CYBB", | |
"ABCB1", | |
"SRC", | |
"ITGAM", | |
"IFNG", | |
"EOMES", | |
"CISH", | |
"TYK2", | |
"GBP5", | |
"RTRAF", | |
"ATM", | |
"IRF1", | |
"TICAM1", | |
"CSF2", | |
"CCR5", | |
"S100A9" | |
], | |
"Coefficient": [ | |
0.1128297306677664, | |
-0.08857158057033955, | |
-0.08414488542942436, | |
0.0821771661931098, | |
0.07665518480038126, | |
-0.07378071369568766, | |
-0.07033864772654765, | |
-0.06996675947689811, | |
-0.0694872905089698, | |
0.0692405880737033, | |
-0.0657196662048922, | |
0.06499805354985222, | |
0.06073244834784003, | |
0.06061950004900303, | |
-0.0592122851812432, | |
-0.05863046594244927, | |
-0.05745243896219017, | |
0.05679774568207133, | |
0.055610644164806426, | |
0.05368753411313467, | |
0.053413796499444235, | |
-0.05316528359387124, | |
0.05198815503580456, | |
-0.05196550407924006, | |
-0.05182529914518154, | |
0.05100380433800081, | |
-0.05081081334759746, | |
0.050704307023094336, | |
-0.050666368042492936, | |
0.0505732581151442, | |
-0.048455711388298205, | |
0.04785523506370984, | |
-0.047604658236537166, | |
0.04716243855530412, | |
0.046988263954313124, | |
-0.04686993590733102, | |
-0.04653405153151659, | |
0.04615719214695211, | |
-0.04609066602420257, | |
-0.04594399295126446, | |
0.04542941374834573, | |
0.04526144708526308, | |
-0.04509773960326215, | |
0.04447047889973553, | |
-0.04433318758037866, | |
-0.044316142090230805, | |
0.04420421788466404, | |
0.0440196883337437, | |
0.04377216785379483, | |
0.04308685007706198, | |
0.042600143960398816, | |
0.042226628122126145, | |
0.042106903372555696, | |
0.042045512520217265, | |
0.04135622470518605, | |
0.03984022075940951, | |
-0.039468326571066456, | |
0.03876148606030965, | |
0.038378309431441236, | |
0.03795816698027754, | |
0.03741649258256326, | |
-0.03691742007498323, | |
0.036681855673438464, | |
-0.03666132019686582, | |
-0.03652248545337565, | |
0.03598417608236412, | |
-0.0355661302097726, | |
-0.03545354946593873, | |
0.03521980333871093, | |
0.0348659513511374, | |
-0.034643551362845505, | |
0.034620981146799394, | |
-0.034556124644364646, | |
-0.03452645478375134, | |
0.03440594513089774, | |
0.03411878324754626, | |
0.03408708488462346, | |
0.03403963871358976, | |
0.03387973517867874, | |
0.03366792992955419, | |
-0.03342760674115222, | |
0.03331866758089225, | |
-0.0331851900763292, | |
0.03305505071576761, | |
-0.032563453870948375, | |
0.03215741762371237, | |
-0.0318502823707087, | |
-0.03182504217668284, | |
-0.0312183050642717, | |
-0.031179835687156272, | |
0.031102969085373335, | |
0.030984319024685143, | |
0.030902773441496556, | |
0.030693291082072152, | |
-0.030635345030684456, | |
0.030436624935332224, | |
0.030154142839514314, | |
-0.030113896333640908, | |
-0.030108378855304888, | |
0.0295878967758888, | |
0.029433770994944923, | |
-0.029389934383964665, | |
0.029302932752813537, | |
-0.02926943884947778, | |
0.029224895110363497, | |
-0.029146203774626324, | |
-0.0289889309409545, | |
0.028980088227818904, | |
0.02893503721379064, | |
0.028851231521948944, | |
0.028775939940136285, | |
0.028489956918628136, | |
0.02843539149973224, | |
-0.028250857097668412, | |
-0.02811797674515729, | |
-0.028089146980850386, | |
-0.027999750859569125, | |
0.027949885969397726, | |
0.027528310266895856, | |
-0.02746173919970948, | |
0.02745266221080003, | |
-0.02745220178435856, | |
-0.027436136589677272, | |
-0.027378098371184177, | |
-0.027372040971596498, | |
-0.027325111275819516, | |
-0.02719886515361593, | |
0.02719363659428777, | |
-0.026305951275438645, | |
-0.026012436404420563, | |
-0.025978385221657973, | |
-0.02574019977823924, | |
0.02555496729264855, | |
-0.025454294033120838, | |
0.02542340710062076, | |
-0.025254564253326117, | |
-0.025173634752411123, | |
-0.02509639662423132, | |
-0.025093993833571228, | |
-0.024995146496090942, | |
0.02479558691388276, | |
0.02479385826978371, | |
-0.0247594377865212, | |
0.024431400585894707, | |
0.024382072220235786, | |
0.024055414242589987, | |
-0.023902501200969203, | |
-0.023452670029840344, | |
0.023353599332842773, | |
-0.02309325783984392, | |
0.023059677074667415, | |
0.02281767440009304, | |
0.02275017255882995, | |
0.022553669421967175, | |
-0.022416093364684447, | |
-0.022344971763712945, | |
0.02224085589302505, | |
0.022023495138678226, | |
-0.02195932302608338, | |
-0.021936302461449605, | |
-0.02186784602933962, | |
-0.021852049583426767, | |
0.02183499174139398, | |
-0.02180202035981197, | |
0.021584198514211634, | |
-0.021317549816131154, | |
0.021085046394735515, | |
0.02104749697570315, | |
-0.0210043656665653, | |
0.020780099662975712, | |
-0.020732840694531816, | |
-0.020665746027689443, | |
0.0206629640292402, | |
0.02055112160806005, | |
-0.020519409011630782, | |
0.020200946295247667, | |
-0.020166638516493716, | |
-0.02002338090789638, | |
-0.01998892383284051, | |
0.01986409901930839, | |
0.01981716177449778, | |
-0.01967467356904726, | |
0.01947391712305794, | |
0.0193619231297741, | |
-0.0192074622259948, | |
-0.019087822316345527, | |
0.018951389942402676, | |
-0.018913187945469336, | |
0.018884613301587392, | |
0.018706914551268262, | |
-0.018530435010545212, | |
0.018462348354632376, | |
0.01834397408301125, | |
-0.018180614216006554, | |
-0.018075723378460862, | |
-0.018029352780088815, | |
-0.017862901811696894, | |
-0.017786215339540355, | |
-0.01776819182324945, | |
-0.017661186359825765, | |
-0.017650086048509796, | |
-0.017393910048208613, | |
0.01725236753131751, | |
-0.017217327668410585, | |
0.017119991894140974, | |
0.016752080982611002, | |
0.0167465595434803, | |
0.01667076220754651, | |
0.016211174866160562, | |
0.016201477291386115, | |
-0.01619563290075617, | |
-0.015949604963858607, | |
-0.015943357429031125, | |
-0.015824673632334564, | |
0.015786184541483738, | |
0.015622930658199896, | |
-0.015607864403002525, | |
-0.015321974179211507, | |
0.015304406664079354, | |
-0.015286322059740764, | |
-0.015272843501081811, | |
-0.01526624645305956, | |
-0.015080110241880018, | |
0.015077023656970546, | |
0.015014607610546174, | |
0.01498449885258225, | |
-0.01497434773456824, | |
0.014892057304901774, | |
0.01483710633787515, | |
-0.014828492195205272, | |
0.014791313312370713, | |
-0.01479044589151997, | |
0.014546624326581369, | |
0.014504011822837108, | |
0.014437097713529143, | |
-0.014428659887920369, | |
-0.014295625977453541, | |
0.014285595949271286, | |
-0.014239227244845427, | |
-0.014194710805086054, | |
-0.013927090954303202, | |
-0.013868309835665078, | |
-0.013798670361931154, | |
-0.01369136961399404, | |
-0.013591890439735434, | |
-0.013537189421293257, | |
-0.013500822338791256, | |
-0.013365259027714245, | |
0.013257913932998924, | |
0.013204483055069416, | |
-0.01320053379232039, | |
-0.013157430593224086, | |
-0.013141109796389718, | |
-0.012960673102116838, | |
-0.012890161645230241, | |
-0.012875155565350916, | |
0.01286513424650538, | |
-0.012843368543939096, | |
0.012834869939501576, | |
0.01271122608319155, | |
0.012623082913894662, | |
0.0125181433258817, | |
-0.012516602912246075, | |
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], | |
"Absolute Coefficient": [ | |
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}, | |
"cv_performance": { | |
"prediction": { | |
"accuracy": 78.26086956521739, | |
"precision": 68.5, | |
"recall": 44.0, | |
"f1": 52.878787878787875 | |
}, | |
"selection": { | |
"precision": 9.459219406774398, | |
"recall": 77.73584905660377, | |
"f1": 16.865350463867514, | |
"jaccard": 9.21120809492831 | |
} | |
} | |
} |