| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "ATG5", | |
| "BATF3", | |
| "BCL2L11", | |
| "B3GAT1", | |
| "C1R", | |
| "C4BPA", | |
| "BCAP31", | |
| "BTK", | |
| "C1QB", | |
| "CD40LG", | |
| "APP", | |
| "DEFB4A", | |
| "CCL8", | |
| "CXCR3", | |
| "IRAK2", | |
| "BCL2", | |
| "HLA-DQA1", | |
| "EBI3", | |
| "LILRB5", | |
| "MAPK14", | |
| "ADGRE2", | |
| "CCL15", | |
| "CD59", | |
| "TLR3", | |
| "C3", | |
| "TP53", | |
| "EGR2", | |
| "BATF", | |
| "FADD", | |
| "CD9", | |
| "IL1R1", | |
| "HRAS", | |
| "HFE", | |
| "CIITA", | |
| "LTB4R", | |
| "FKBP5", | |
| "CD86", | |
| "CXCR2", | |
| "DEFB103A", | |
| "CR2", | |
| "PTGS2", | |
| "BST2", | |
| "CD53", | |
| "CCL20", | |
| "CCL3", | |
| "FYN", | |
| "CARD9", | |
| "PSMB5", | |
| "CCND3", | |
| "PTAFR", | |
| "BCL3", | |
| "CTNNB1", | |
| "DEFB103B", | |
| "IL4R", | |
| "IL7", | |
| "SLC2A1", | |
| "NFATC2", | |
| "ATG16L1", | |
| "S1PR1", | |
| "FCAR", | |
| "IKZF1", | |
| "KLRC3", | |
| "CCL5", | |
| "CCR8", | |
| "CRADD", | |
| "POLR1G", | |
| "MBP", | |
| "IGF2R", | |
| "NT5E", | |
| "CD14", | |
| "CCL22", | |
| "MALT1", | |
| "IRGM", | |
| "MAPKAPK2", | |
| "IL6", | |
| "FN1", | |
| "FAS", | |
| "CFI", | |
| "IL17A", | |
| "IRF7", | |
| "ATG12", | |
| "TNFSF11", | |
| "CFH", | |
| "CD160", | |
| "LTB4R2", | |
| "CXCL11", | |
| "CD80", | |
| "CCRL2", | |
| "AIRE", | |
| "CD46", | |
| "ABL1", | |
| "FOXP3", | |
| "CCL13", | |
| "CD79B", | |
| "LCP2", | |
| "ACKR4", | |
| "CCL2", | |
| "ITGA5", | |
| "KLRA1P", | |
| "CD19", | |
| "NOTCH2", | |
| "RAG2", | |
| "FCER1A", | |
| "HLA-DRB3", | |
| "DEFB1", | |
| "SPP1", | |
| "IL22", | |
| "MUC1", | |
| "PSMC2", | |
| "CFD", | |
| "NOD2", | |
| "CD36", | |
| "FCGR2B", | |
| "ATG10", | |
| "CCL19", | |
| "LIF", | |
| "NLRP3", | |
| "SELPLG", | |
| "MAP4K4", | |
| "SELE", | |
| "IL13RA1", | |
| "PDCD1", | |
| "IL1RAP", | |
| "ZBTB16", | |
| "EGR1", | |
| "MX1", | |
| "ATG7", | |
| "GZMK", | |
| "IL10", | |
| "IL4", | |
| "EDNRB", | |
| "IL16", | |
| "IL32", | |
| "IL21R", | |
| "CFB", | |
| "IL1B", | |
| "CUL9", | |
| "BCL10", | |
| "BLNK", | |
| "BTLA", | |
| "CD1D", | |
| "IL21", | |
| "CD7", | |
| "TNFSF15", | |
| "STAT4", | |
| "CD4", | |
| "MSR1", | |
| "GP1BB", | |
| "POU2F2", | |
| "CSF2", | |
| "SLAMF6", | |
| "TLR4", | |
| "CD274", | |
| "IFI16", | |
| "AICDA", | |
| "ITLN2", | |
| "PDCD2", | |
| "IL1RN", | |
| "CLEC5A", | |
| "KCNJ2", | |
| "ITGA2B", | |
| "TIRAP", | |
| "IL26", | |
| "ITGB1", | |
| "TCF7", | |
| "BAX", | |
| "IL7R", | |
| "TNFSF8", | |
| "TOLLIP", | |
| "CD48", | |
| "TNFSF13B", | |
| "CD70", | |
| "CD1A", | |
| "IRF5", | |
| "CLEC6A", | |
| "IRF3", | |
| "TNFRSF17", | |
| "SLAMF1", | |
| "ITGA4", | |
| "KLRG1", | |
| "IL2RA", | |
| "CXCL8", | |
| "CCL16", | |
| "CCR6", | |
| "TGFBI", | |
| "CCR1", | |
| "PDCD1LG2", | |
| "RAG1", | |
| "IL3", | |
| "IFI35", | |
| "CX3CR1", | |
| "MAPK11", | |
| "CLU", | |
| "CCR2", | |
| "CTSC", | |
| "CCL4", | |
| "HLA-C", | |
| "MME", | |
| "CXCL1", | |
| "TAPBP", | |
| "IFNA2", | |
| "CASP8", | |
| "IRAK1", | |
| "TRAF1", | |
| "IRF4", | |
| "PRKCD", | |
| "PAX5", | |
| "HLA-DMB", | |
| "CD163", | |
| "UBE2L3", | |
| "LCK", | |
| "TLR1", | |
| "PTPN2", | |
| "IRAK4", | |
| "TNFRSF10C", | |
| "CCR10", | |
| "B2M", | |
| "MIF", | |
| "CCL26", | |
| "TAGAP", | |
| "IL12B", | |
| "HAVCR2", | |
| "CASP10", | |
| "C5", | |
| "CXCR6", | |
| "NCAM1", | |
| "IL6R", | |
| "CD8B", | |
| "CD58", | |
| "KLRG2", | |
| "MS4A1", | |
| "ENTPD1", | |
| "TCF4", | |
| "PSMB7", | |
| "ARHGDIB", | |
| "MYD88", | |
| "CD96", | |
| "CD164", | |
| "CDKN1A", | |
| "IL10RA", | |
| "IL15", | |
| "IFNL1", | |
| "CLEC4E", | |
| "ITGAL", | |
| "IKBKE", | |
| "ITGB2", | |
| "PLA2G2E", | |
| "TRAF4", | |
| "CCL23", | |
| "STAT1", | |
| "CD8A", | |
| "C1QA", | |
| "STAT3", | |
| "ICAM3", | |
| "BST1", | |
| "PML", | |
| "NFATC1", | |
| "TLR9", | |
| "ICAM1", | |
| "TLR2", | |
| "TNFSF12", | |
| "CEACAM6", | |
| "IL2RG", | |
| "CD99", | |
| "ADA", | |
| "IL27", | |
| "CXCL12", | |
| "CD28", | |
| "RELB", | |
| "HLA-DPA1", | |
| "CD276", | |
| "PLAU", | |
| "CSF1", | |
| "IFNAR1", | |
| "CSF2RB", | |
| "STAT5A", | |
| "IFIH1", | |
| "PDGFB", | |
| "PTGER4", | |
| "SMAD5", | |
| "SYK", | |
| "CXCL2", | |
| "MRC1", | |
| "IL6ST", | |
| "C6", | |
| "IFNB1", | |
| "TNFRSF9", | |
| "KLRB1", | |
| "TGFBR1", | |
| "XCL1", | |
| "ITGAM", | |
| "TLR5", | |
| "CD34", | |
| "CD74", | |
| "CD81", | |
| "PRDM1", | |
| "LILRB2", | |
| "CR1", | |
| "CCL11", | |
| "VCAM1", | |
| "NOTCH1", | |
| "C7", | |
| "IL2RB", | |
| "CD40", | |
| "IL17F", | |
| "CEBPB", | |
| "S100A8", | |
| "KIR3DL1", | |
| "KLRC1", | |
| "C1QBP", | |
| "NFKBIZ", | |
| "CD55", | |
| "IL20", | |
| "HAMP", | |
| "PSMD7", | |
| "IKBKB", | |
| "GATA3", | |
| "PLAUR", | |
| "FCGRT", | |
| "PDGFRB", | |
| "JAK3", | |
| "TLR8", | |
| "LAIR1", | |
| "LITAF", | |
| "CD2", | |
| "C1S", | |
| "CD3D", | |
| "HLA-A", | |
| "IL11RA", | |
| "TNFRSF1B", | |
| "FCGR2A", | |
| "THY1", | |
| "RTRAF", | |
| "IL5", | |
| "TRAF6", | |
| "IL1RL2", | |
| "XCR1", | |
| "ARG2", | |
| "CCL18", | |
| "IL18", | |
| "NCF4", | |
| "PRF1", | |
| "TNFRSF11A", | |
| "AHR", | |
| "IRAK3", | |
| "LAG3", | |
| "MR1", | |
| "CCR5", | |
| "CD83", | |
| "KIT", | |
| "SOCS3", | |
| "CX3CL1", | |
| "SERPING1", | |
| "BCL6", | |
| "LILRA6", | |
| "TBK1", | |
| "HLA-DPB1", | |
| "BID", | |
| "KLRF1", | |
| "GBP5", | |
| "LILRA1", | |
| "NFKB2", | |
| "GPI", | |
| "CD6", | |
| "TGFBR2", | |
| "LTA", | |
| "CASP2", | |
| "NOD1", | |
| "TNFSF4", | |
| "HLA-DOB", | |
| "ELP1", | |
| "TFRC", | |
| "GBP1", | |
| "IL23R", | |
| "ITGA6", | |
| "IFNL2", | |
| "ABCB1", | |
| "ARG1", | |
| "CCL7", | |
| "STAT6", | |
| "ICOS", | |
| "KIR3DL3", | |
| "C9", | |
| "TYK2", | |
| "CSF3R", | |
| "IFIT2", | |
| "CMKLR1", | |
| "IL12A", | |
| "MAF", | |
| "ITGAE", | |
| "LY96", | |
| "TNFRSF13B", | |
| "CYBB", | |
| "NOS2", | |
| "LILRB1", | |
| "LAMP3", | |
| "HLA-B", | |
| "IFNGR1", | |
| "CXCL13", | |
| "CEACAM8", | |
| "CLEC7A", | |
| "ICOSLG", | |
| "ICAM5", | |
| "SOCS1", | |
| "PSMB9", | |
| "TNFRSF8", | |
| "MAPK1", | |
| "CD244", | |
| "IKZF3", | |
| "CD247", | |
| "CD24", | |
| "IL9", | |
| "IKZF2", | |
| "IRF8", | |
| "ATM", | |
| "ILF3", | |
| "TAP2", | |
| "RUNX1", | |
| "PIGR", | |
| "TNF", | |
| "PTPN6", | |
| "CD5", | |
| "TIGIT", | |
| "MASP1", | |
| "PLAAT4", | |
| "LGALS3", | |
| "CD79A", | |
| "CD82", | |
| "HLA-DMA", | |
| "NCR1", | |
| "IRF1", | |
| "IL18RAP", | |
| "TNFRSF14", | |
| "CDH5", | |
| "IDO1", | |
| "HLA-DRB1", | |
| "CD27", | |
| "PTPN22", | |
| "CHUK", | |
| "CASP3", | |
| "DUSP4", | |
| "LILRA3", | |
| "CFP", | |
| "LTF", | |
| "LTBR", | |
| "RAF1", | |
| "IL13", | |
| "CD44", | |
| "GZMB", | |
| "HLA-DQB1", | |
| "PTK2", | |
| "MASP2", | |
| "RORC", | |
| "STAT5B", | |
| "LEF1", | |
| "PPARG", | |
| "XBP1", | |
| "TRAF3", | |
| "DPP4", | |
| "JAK1", | |
| "C2", | |
| "CSF1R", | |
| "SLAMF7", | |
| "ITGAX", | |
| "TNFSF10", | |
| "KLRC4", | |
| "IL18R1", | |
| "TRAF2", | |
| "LILRB3", | |
| "KLRC2", | |
| "HLA-DRA", | |
| "LILRA5", | |
| "CTSG", | |
| "GNLY", | |
| "IL19", | |
| "CLEC4A", | |
| "CISH", | |
| "ICAM4", | |
| "ICAM2", | |
| "NFATC3", | |
| "LILRA2", | |
| "CEACAM1", | |
| "ZEB1", | |
| "TICAM1", | |
| "CASP1", | |
| "MBL2", | |
| "TAL1", | |
| "TAP1", | |
| "IL1R2", | |
| "IL1A", | |
| "SH2D1A", | |
| "IFITM1", | |
| "VTN", | |
| "KIR3DL2", | |
| "IL12RB1", | |
| "GFI1", | |
| "CXCR4", | |
| "SRC", | |
| "KLRD1", | |
| "CXCL10", | |
| "LILRA4", | |
| "C8A", | |
| "IL17B", | |
| "GZMA", | |
| "NFIL3", | |
| "PPBP", | |
| "CTSS", | |
| "TNFAIP6", | |
| "LILRB4", | |
| "FCER1G", | |
| "IFNG", | |
| "CD22", | |
| "TNFAIP3", | |
| "CD3E", | |
| "JAK2", | |
| "ITLN1", | |
| "CD209", | |
| "CCL24", | |
| "S100A9", | |
| "CXCR1", | |
| "PLA2G2A", | |
| "RELA", | |
| "KLRK1", | |
| "MAP4K1", | |
| "MCL1", | |
| "SMAD3", | |
| "MARCO", | |
| "MAP4K2", | |
| "IL22RA2", | |
| "EOMES", | |
| "PSMB10", | |
| "SELL", | |
| "TGFB1", | |
| "STAT2", | |
| "IL2", | |
| "C8B", | |
| "CXCL9", | |
| "PSMB8", | |
| "IL1RL1", | |
| "NFKB1", | |
| "PECAM1", | |
| "NFKBIA", | |
| "SKI", | |
| "GPR183", | |
| "TRAF5", | |
| "SIGIRR", | |
| "CAMP", | |
| "TNFRSF13C", | |
| "IKBKG", | |
| "ZAP70", | |
| "IFNAR2", | |
| "CCR7", | |
| "ETS1", | |
| "TLR7", | |
| "TBX21", | |
| "TNFRSF4", | |
| "PYCARD", | |
| "IL23A", | |
| "C8G", | |
| "KLRF2", | |
| "STING1" | |
| ], | |
| "Coefficient": [ | |
| 0.11814366484330871, | |
| -0.0874907275774938, | |
| 0.07959258570699687, | |
| 0.07658645860582275, | |
| 0.07588977312188608, | |
| -0.07404782350295391, | |
| 0.07339169878400766, | |
| -0.07255196134685495, | |
| 0.06958519346002524, | |
| 0.06911731209794686, | |
| 0.06749996481077085, | |
| -0.06558850479794408, | |
| -0.06526800473808252, | |
| 0.0650040077683256, | |
| -0.06311675083502016, | |
| 0.0628463022232802, | |
| 0.06273612141689222, | |
| 0.06219238634987284, | |
| -0.06038110592687226, | |
| -0.05949495526680278, | |
| -0.058612288696920214, | |
| 0.057841091368728566, | |
| -0.057492727189899354, | |
| 0.05661025666984566, | |
| 0.05647023954190514, | |
| -0.05617469399821319, | |
| -0.05556455712059039, | |
| 0.05536203580174397, | |
| -0.05534016304071442, | |
| -0.0547220178080524, | |
| 0.05467189404180147, | |
| 0.054184770909682836, | |
| -0.05369446961118687, | |
| 0.05243766982506488, | |
| 0.05217170581568306, | |
| -0.052005673206203126, | |
| -0.05152473232631186, | |
| 0.051358367167133226, | |
| 0.051211298240828866, | |
| 0.050751621368122224, | |
| 0.05013462682453027, | |
| 0.0495604115996983, | |
| 0.04934472313853114, | |
| -0.04864344270082043, | |
| -0.04735495264904836, | |
| 0.04676580481347609, | |
| -0.04602891202077109, | |
| 0.045881439643425406, | |
| 0.04586415818790407, | |
| 0.04581262551099294, | |
| -0.045626415475628665, | |
| -0.045286595110260244, | |
| 0.04512101443163998, | |
| 0.04436152954880078, | |
| -0.044319528114761385, | |
| 0.04406431426597327, | |
| -0.043465949005853176, | |
| -0.04342146890350683, | |
| -0.04319783165152997, | |
| -0.04297259427345121, | |
| -0.042906681333581664, | |
| 0.0426122017107907, | |
| 0.04257208413487974, | |
| 0.04207064546985966, | |
| -0.041995789650250144, | |
| 0.0419905036167896, | |
| -0.04195717360319819, | |
| -0.03962958406255688, | |
| 0.03898823993955751, | |
| 0.03876408615762586, | |
| 0.03841309613158595, | |
| -0.038382824221886463, | |
| 0.038378804132062606, | |
| 0.03834538304754598, | |
| 0.03833642800725394, | |
| 0.03831729504996955, | |
| 0.03804135462642151, | |
| 0.037489578008695915, | |
| -0.03748415883728428, | |
| 0.03748369488224924, | |
| 0.037369509747704484, | |
| -0.03721607330800481, | |
| 0.037197544563317204, | |
| 0.036869087508192455, | |
| 0.03676965792368959, | |
| -0.036702936278758355, | |
| -0.03668600499820147, | |
| 0.036440409042613926, | |
| -0.0363861635677794, | |
| -0.03631986042047284, | |
| -0.036197009733655874, | |
| -0.03617896755025741, | |
| -0.036108866117641, | |
| -0.035910676955997096, | |
| -0.03559220993000267, | |
| 0.03537002857072656, | |
| 0.03489433933012669, | |
| 0.03460871033644361, | |
| 0.0345565377418993, | |
| 0.034539660858442865, | |
| 0.034479633558878967, | |
| -0.033939089009460716, | |
| -0.0336128892053916, | |
| -0.033429717988733516, | |
| -0.03341665281153685, | |
| 0.033238642861216805, | |
| 0.033008352646660445, | |
| -0.032825775067615935, | |
| -0.03259712776619334, | |
| 0.03258525975013264, | |
| -0.03206168586306051, | |
| -0.03197270559219446, | |
| -0.031720858226736634, | |
| 0.03168260958330458, | |
| 0.0316812001082199, | |
| 0.03155100973217375, | |
| -0.031498639350540834, | |
| 0.03147034290299964, | |
| 0.03120725305125665, | |
| -0.03101094874765951, | |
| 0.030923755128240714, | |
| 0.03086932309871275, | |
| -0.030854164410069294, | |
| -0.03017873314426051, | |
| 0.030169539464264424, | |
| 0.029827866810844563, | |
| 0.029601130685712747, | |
| -0.029511248121577526, | |
| -0.029056575159874, | |
| 0.02894737392089333, | |
| 0.028798342698922397, | |
| 0.02874169212962192, | |
| 0.028719876572245784, | |
| 0.02835560912158019, | |
| -0.028326183076328636, | |
| -0.02820630090403311, | |
| 0.0281161442347041, | |
| -0.02802703650203543, | |
| 0.028014077564501434, | |
| -0.027777953090421165, | |
| 0.027772256882641767, | |
| -0.027681574519033744, | |
| -0.027655416580103273, | |
| 0.02713160894981482, | |
| -0.027079103183299782, | |
| -0.02703497305743107, | |
| -0.026851039798644907, | |
| -0.02684164933003578, | |
| -0.0268072985426379, | |
| 0.026523626068552294, | |
| 0.026468599312462763, | |
| -0.02642162705683922, | |
| -0.026364631419975665, | |
| 0.026281245769714082, | |
| -0.026232673786186274, | |
| -0.026183306744440613, | |
| -0.025915508020673536, | |
| 0.025797454001922127, | |
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| -0.025775916260940616, | |
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| ], | |
| "Absolute Coefficient": [ | |
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| ] | |
| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 59.1304347826087, | |
| "precision": 33.93650793650793, | |
| "recall": 47.33333333333333, | |
| "f1": 39.14912280701755 | |
| }, | |
| "selection": { | |
| "precision": 9.450789406671758, | |
| "recall": 100.0, | |
| "f1": 17.26947622362387, | |
| "jaccard": 9.450789406671758 | |
| } | |
| } | |
| } |