{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "C1R",
            "CXCR3",
            "BTK",
            "C4BPA",
            "BCAP31",
            "CD40LG",
            "DEFB4A",
            "B3GAT1",
            "APP",
            "C1QB",
            "BCL2",
            "ADGRE2",
            "CCL15",
            "HLA-DQA1",
            "MAPK14",
            "CD59",
            "LILRB5",
            "CCL8",
            "C3",
            "EBI3",
            "CCL3",
            "IRAK2",
            "TP53",
            "IL1R1",
            "CD9",
            "CD86",
            "CXCR2",
            "TLR3",
            "CR2",
            "LTB4R",
            "CCND3",
            "DEFB103B",
            "HRAS",
            "FADD",
            "EGR2",
            "DEFB103A",
            "CD14",
            "CD53",
            "FYN",
            "FKBP5",
            "PTGS2",
            "CFI",
            "ACKR4",
            "BATF",
            "PSMB5",
            "IKZF1",
            "BST2",
            "MBP",
            "CARD9",
            "CCL22",
            "IL4R",
            "POLR1G",
            "CIITA",
            "BCL3",
            "PTAFR",
            "CCL20",
            "SLC2A1",
            "ATG12",
            "NFATC2",
            "IL7",
            "S1PR1",
            "CCL5",
            "NT5E",
            "HFE",
            "CRADD",
            "FCAR",
            "CCR8",
            "CD46",
            "CTNNB1",
            "IRF7",
            "LTB4R2",
            "MAPKAPK2",
            "FOXP3",
            "IGF2R",
            "CCL13",
            "TNFSF11",
            "KLRC3",
            "RAG2",
            "FAS",
            "IL17A",
            "MUC1",
            "HLA-DRB3",
            "EGR1",
            "CD160",
            "IRGM",
            "PDCD1",
            "LCP2",
            "ATG16L1",
            "CFH",
            "CD79B",
            "IL6",
            "MALT1",
            "CD80",
            "DEFB1",
            "NLRP3",
            "IL22",
            "AIRE",
            "NOTCH2",
            "KLRA1P",
            "SPP1",
            "IL4",
            "TIRAP",
            "FN1",
            "ABL1",
            "IL3",
            "MX1",
            "IRAK1",
            "IL10",
            "SELE",
            "IFI16",
            "NOD2",
            "CFB",
            "GP1BB",
            "IL32",
            "CFD",
            "ITGA5",
            "LIF",
            "IL21R",
            "CD4",
            "CXCL11",
            "IL1RAP",
            "CUL9",
            "PSMC2",
            "PDCD2",
            "MAP4K4",
            "ARHGDIB",
            "CCL16",
            "CD7",
            "ITGA4",
            "FCGR2B",
            "CD36",
            "ZBTB16",
            "CLU",
            "SELPLG",
            "CD1D",
            "IL1B",
            "CD55",
            "BAX",
            "SLAMF6",
            "FCER1A",
            "AICDA",
            "IL21",
            "MSR1",
            "RAG1",
            "TLR4",
            "BST1",
            "KCNJ2",
            "IRF3",
            "IL16",
            "CCR1",
            "BCL10",
            "CLEC6A",
            "IRF5",
            "PLAU",
            "GZMK",
            "CCL2",
            "CXCL1",
            "ITGB1",
            "TNFSF8",
            "TCF7",
            "CD40",
            "CCRL2",
            "IL13RA1",
            "EDNRB",
            "BLNK",
            "CCR2",
            "PDCD1LG2",
            "IL7R",
            "CD70",
            "ITGA2B",
            "CD96",
            "TNFSF13B",
            "MAPK11",
            "TNFSF15",
            "CLEC5A",
            "KLRG2",
            "CD19",
            "TRAF4",
            "ITGAL",
            "PAX5",
            "UBE2L3",
            "IL1RN",
            "TOLLIP",
            "STAT4",
            "CXCL8",
            "CD276",
            "TNFRSF17",
            "POU2F2",
            "ATG10",
            "IRAK4",
            "TGFBI",
            "IL27",
            "BTLA",
            "C1QBP",
            "IL26",
            "TAPBP",
            "PLA2G2E",
            "ITLN2",
            "TLR1",
            "TAGAP",
            "HLA-DMB",
            "CD1A",
            "CCL19",
            "CD8B",
            "IL2RA",
            "PML",
            "TNFRSF10C",
            "CDKN1A",
            "ADA",
            "PRKCD",
            "HAVCR2",
            "IL12B",
            "PSMB7",
            "IFI35",
            "TCF4",
            "KLRG1",
            "C5",
            "TRAF1",
            "MS4A1",
            "ENTPD1",
            "CCL23",
            "CR1",
            "B2M",
            "CD8A",
            "TNFSF12",
            "IFNA2",
            "XCL1",
            "CSF2",
            "CSF2RB",
            "TLR2",
            "ATG7",
            "MME",
            "CXCL2",
            "CXCR6",
            "MIF",
            "TLR9",
            "CCR6",
            "PTPN2",
            "CCL4",
            "CCR10",
            "CLEC4E",
            "MYD88",
            "ITGAM",
            "C1QA",
            "CD274",
            "CD34",
            "RELB",
            "HLA-C",
            "IFNL1",
            "LCK",
            "VCAM1",
            "IL15",
            "IKBKE",
            "CASP3",
            "CASP8",
            "CASP10",
            "IL6R",
            "IRF4",
            "FCGRT",
            "CD74",
            "CCL18",
            "C6",
            "SLAMF1",
            "IL6ST",
            "CTSC",
            "CD58",
            "SMAD5",
            "PDGFB",
            "LILRB2",
            "NFKBIZ",
            "CCL11",
            "IKBKB",
            "PTGER4",
            "KLRB1",
            "HLA-DPA1",
            "TNFRSF11A",
            "CXCL12",
            "CX3CR1",
            "CEACAM6",
            "CD48",
            "IFNAR1",
            "ARG1",
            "GATA3",
            "SYK",
            "NCAM1",
            "IL5",
            "IFNL2",
            "IL2RG",
            "IL10RA",
            "CD81",
            "CD83",
            "ICAM3",
            "IFIH1",
            "XCR1",
            "STAT3",
            "HLA-DMA",
            "TGFBR1",
            "MRC1",
            "STAT5A",
            "TLR5",
            "PSMD7",
            "CD99",
            "NCF4",
            "FCGR2A",
            "STAT1",
            "KLRC1",
            "CD164",
            "GBP5",
            "IL17F",
            "CD6",
            "SOCS3",
            "PDGFRB",
            "LITAF",
            "ITGB2",
            "KIR3DL1",
            "NOTCH1",
            "NFATC1",
            "RTRAF",
            "IL20",
            "IFNGR1",
            "LAIR1",
            "CCL26",
            "IL23R",
            "CD79A",
            "TNFRSF1B",
            "CSF1",
            "CD163",
            "HLA-A",
            "THY1",
            "NFKB2",
            "CASP2",
            "ICAM1",
            "TRAF6",
            "ITGAE",
            "IL1A",
            "PRDM1",
            "HLA-DOB",
            "TBK1",
            "PLAUR",
            "LAG3",
            "CEBPB",
            "CD28",
            "TNFSF4",
            "TGFBR2",
            "DPP4",
            "TNF",
            "BCL6",
            "IL18",
            "JAK3",
            "MASP1",
            "S100A8",
            "HAMP",
            "IL12A",
            "LTA",
            "C1S",
            "LILRA1",
            "IRAK3",
            "CD3D",
            "CD82",
            "ELP1",
            "CSF3R",
            "HLA-DPB1",
            "GFI1",
            "CD2",
            "KIR3DL3",
            "NOS2",
            "LILRA6",
            "IFNB1",
            "CD27",
            "TLR8",
            "IL11RA",
            "LAMP3",
            "MAF",
            "IL2RB",
            "ITGA6",
            "LILRB1",
            "C9",
            "IL12RB1",
            "IRF8",
            "STAT6",
            "CD5",
            "SERPING1",
            "PTK2",
            "CXCL13",
            "CEACAM1",
            "IL9",
            "TFRC",
            "ICOSLG",
            "CXCR1",
            "IKZF3",
            "DUSP4",
            "GPI",
            "C7",
            "CTSG",
            "LY96",
            "ARG2",
            "CCR5",
            "AHR",
            "NOD1",
            "LILRA5",
            "CMKLR1",
            "CD244",
            "PLAAT4",
            "MBL2",
            "XBP1",
            "KLRF1",
            "TYK2",
            "IRF1",
            "C8A",
            "PSMB9",
            "SOCS1",
            "TIGIT",
            "IL19",
            "PRF1",
            "ICOS",
            "MAPK1",
            "IL1RL2",
            "ABCB1",
            "FCER1G",
            "CYBB",
            "SLAMF7",
            "IFIT2",
            "MASP2",
            "GZMB",
            "CD24",
            "TNFRSF13B",
            "TRAF3",
            "IL18RAP",
            "TICAM1",
            "TAP2",
            "TNFRSF9",
            "KLRK1",
            "JAK1",
            "CD44",
            "CDH5",
            "IL13",
            "TNFRSF14",
            "CSF1R",
            "LTBR",
            "LTF",
            "IDO1",
            "ZEB1",
            "NFIL3",
            "ICAM4",
            "LILRA4",
            "CEACAM8",
            "PTPN6",
            "CD247",
            "IL1RL1",
            "RUNX1",
            "IL18R1",
            "KLRD1",
            "CLEC7A",
            "RORC",
            "KIT",
            "LILRA2",
            "LGALS3",
            "RAF1",
            "IKZF2",
            "MR1",
            "C2",
            "ILF3",
            "CISH",
            "CD209",
            "TRAF2",
            "TNFAIP3",
            "MAP4K1",
            "PPBP",
            "LEF1",
            "HLA-DQB1",
            "TNFSF10",
            "CTSS",
            "KLRC2",
            "KLRF2",
            "CFP",
            "MARCO",
            "IKBKG",
            "PYCARD",
            "LILRB3",
            "SRC",
            "SIGIRR",
            "RELA",
            "TLR7",
            "PLA2G2A",
            "TAP1",
            "CX3CL1",
            "LILRB4",
            "TNFRSF8",
            "SKI",
            "CXCL9",
            "IFNG",
            "IL17B",
            "TNFRSF4",
            "VTN",
            "PECAM1",
            "PPARG",
            "CD22",
            "CXCR4",
            "GPR183",
            "IL23A",
            "CCL24",
            "NFKB1",
            "TNFAIP6",
            "HLA-DRA",
            "TAL1",
            "NFKBIA",
            "EOMES",
            "HLA-B",
            "CXCL10",
            "GBP1",
            "MAP4K2",
            "HLA-DRB1",
            "NCR1",
            "STAT5B",
            "LILRA3",
            "IFNAR2",
            "PIGR",
            "IL22RA2",
            "CCL7",
            "IFITM1",
            "ITLN1",
            "C8B",
            "CD3E",
            "ZAP70",
            "TBX21",
            "NFATC3",
            "STAT2",
            "CLEC4A",
            "S100A9",
            "CHUK",
            "SELL",
            "TRAF5",
            "TGFB1",
            "GNLY",
            "PSMB8",
            "PTPN22",
            "ICAM2",
            "STING1",
            "ITGAX",
            "ATM",
            "CASP1",
            "KLRC4",
            "ETS1",
            "ICAM5",
            "IL2",
            "IL1R2",
            "JAK2",
            "TNFRSF13C",
            "CAMP",
            "KIR3DL2",
            "C8G",
            "SH2D1A",
            "SMAD3",
            "PSMB10",
            "GZMA",
            "BID",
            "CCR7",
            "MCL1"
        ],
        "Coefficient": [
            0.12010983412961693,
            -0.08230522514940028,
            0.0809850249882292,
            0.07551687706904034,
            0.0751329562427045,
            -0.07384517693696166,
            -0.07284814709635218,
            0.07185944017201776,
            0.07096467740891853,
            -0.0703043806612227,
            0.06997452329424785,
            0.06861185940432425,
            0.06727431646852043,
            0.06675130605690126,
            -0.0662397887206338,
            0.06602988494195773,
            0.063621521967359,
            -0.061482928074305755,
            -0.06024118729361058,
            -0.06023038343813967,
            -0.06004635286560713,
            0.0589500098573293,
            0.058710531969817535,
            -0.05870264029512842,
            -0.058683696142905015,
            -0.057289209608320804,
            0.056538300030707846,
            -0.056120130198834293,
            -0.0554765790518687,
            0.05456244945792532,
            0.05422683326468514,
            0.05412379716901149,
            0.054122853092011654,
            0.0531856644102409,
            0.051442942096445295,
            0.049673445563373136,
            -0.049660934012046125,
            -0.04930558996662544,
            0.04910427138452318,
            0.04890985984478805,
            0.048834226425245965,
            0.04813493815381912,
            -0.0478016153855334,
            0.04777261063692748,
            0.047533275301887175,
            0.04656275480893187,
            0.04615384170755395,
            0.04559205818147757,
            -0.04522591010255776,
            0.04479612941152424,
            -0.04479224796303098,
            -0.044265901896087465,
            0.04421077609713332,
            0.043503847844878554,
            0.04350350853738585,
            0.042605218519779546,
            -0.042454604519278585,
            0.04212207172483562,
            -0.04190544065529846,
            0.04125502099849283,
            0.04119786611983019,
            -0.04117233638151156,
            -0.040829548279684304,
            -0.04070310962568545,
            0.04013833587270663,
            0.04010317882052971,
            -0.03999671316516254,
            -0.03995349123192214,
            -0.039599624134334065,
            0.03923122835892887,
            -0.039101378816982446,
            -0.038795279060418374,
            0.03846347104829722,
            0.038407968138471554,
            0.03832346899115994,
            -0.03827776579046292,
            -0.038167493940463745,
            -0.03750254361861628,
            -0.03738437798634655,
            0.03723390396410669,
            -0.03716590381445131,
            0.037087654785455774,
            -0.03708528565248964,
            -0.03589741785185645,
            -0.035777284370230776,
            0.03575705183513473,
            0.03500332907482904,
            0.034841443812404685,
            0.03439612123085585,
            -0.03432269498817475,
            -0.03420335140364615,
            0.03400630916438013,
            -0.03356247784297612,
            0.03329167450196704,
            -0.03325445662627317,
            -0.033208218833332734,
            -0.03316642006875083,
            -0.03294769070263014,
            0.03287969764903851,
            -0.032843763900944775,
            0.03276367976061974,
            0.03251173577149319,
            0.032271055407205575,
            0.03201938570435819,
            -0.0315458451663511,
            0.03142758229149974,
            -0.03133362343045387,
            -0.031312084500554206,
            0.031297996250873886,
            0.031081838255602574,
            -0.031042352600618793,
            -0.03100554274460307,
            0.030903710244346412,
            -0.030824464807856326,
            -0.030818845087254975,
            -0.03070077680243377,
            0.03066196762636635,
            0.030650192557914267,
            0.03064354499152373,
            0.03054797590544755,
            0.030510395178357845,
            -0.030358550203094,
            -0.030058747900533336,
            -0.02983515524888632,
            0.029818252961236223,
            -0.029808400374422627,
            -0.029601629052178547,
            0.02949911722710075,
            0.02940878737268203,
            -0.029280868089820947,
            -0.02909020392417769,
            -0.028895228737015985,
            -0.02885319736065615,
            -0.028842934323274002,
            -0.028741734117735916,
            -0.02869639457438609,
            0.028486511452357376,
            0.028376141654135618,
            -0.028325671712560705,
            0.028022289170037296,
            0.027855925390726184,
            0.027564994409461044,
            -0.02752664599471113,
            -0.02751490843853885,
            -0.027452573560238832,
            -0.027155437826754062,
            0.027103606366051358,
            -0.02708624452149003,
            0.026929792352275016,
            -0.026884970181173327,
            0.02665365914209397,
            0.026602850613462386,
            0.02632077288652532,
            -0.02631887863929609,
            -0.026290096919485483,
            -0.025961740791013783,
            -0.02594122890502934,
            -0.02590200242531486,
            0.02585640164772565,
            0.025767829408896742,
            0.025756184117608237,
            0.025754241518496413,
            0.025598391046658744,
            -0.025533373842081333,
            0.02548697365741341,
            0.02545789395101945,
            0.02534157357335606,
            0.025218031020932525,
            -0.0252025999809671,
            0.025058759037878686,
            -0.025028606345514164,
            0.025019362745706184,
            0.024961674687842612,
            -0.024665097904084048,
            -0.024515783453731076,
            0.024369350800169883,
            0.02429598967979037,
            -0.02414751562343894,
            0.024019868707527186,
            0.0234690202933842,
            -0.02331760949493517,
            0.023313841775051854,
            -0.02316025777963263,
            -0.02313075944691409,
            0.023091245864066873,
            0.023089479611606,
            -0.023048854911107097,
            0.022977195289509464,
            -0.02295141329509623,
            0.022924295941823294,
            -0.022844965073354536,
            0.022693681712134057,
            -0.022689212719291824,
            0.022638182173543395,
            -0.022440733813940763,
            -0.022432319856278353,
            0.022399913232862542,
            -0.022332126438195373,
            0.022314786896195465,
            0.02202018277032127,
            -0.02201222049135309,
            -0.021826679492489426,
            -0.021792287699864882,
            0.021782905403817186,
            -0.02176644532282149,
            0.021602502900939544,
            0.02159725525367063,
            -0.021579137332575302,
            0.021528755805128946,
            -0.02151327220117771,
            -0.021510981297003972,
            0.02136214601395016,
            -0.02135575080396039,
            -0.02132260826935661,
            0.02132118014034626,
            0.021156530381246,
            0.020975372414141623,
            -0.020958641320292046,
            -0.020929047944369596,
            -0.02084230111204167,
            -0.02064081532838058,
            -0.02051001194162879,
            -0.020494936706311043,
            -0.020275933520557142,
            0.020273097642594242,
            -0.020222435923132224,
            -0.02015860918924904,
            0.020136550956022372,
            -0.020071729216935397,
            0.019999102242716917,
            0.019840755012317614,
            0.019610749641417884,
            0.01956686117448692,
            0.019436590142572156,
            -0.019433665301787275,
            -0.01936759964942822,
            -0.019279800707973707,
            0.019177118425587444,
            0.019160937180098772,
            -0.019092175024044013,
            0.019008166021866505,
            -0.01898599759644168,
            -0.01896550262593282,
            0.018795439146515876,
            0.01876609396782375,
            -0.018746378036515948,
            -0.01870996466303349,
            -0.0186745520516034,
            0.01862082730376019,
            0.018480425456213135,
            -0.018342625622592652,
            0.01826013161004557,
            0.01815023226963712,
            0.018009655886214143,
            -0.017949043929152454,
            -0.01787936249588435,
            -0.017847560827783895,
            0.0177435873256439,
            -0.017716414047618412,
            0.017689772669327728,
            0.017642199935391317,
            0.01759800341712737,
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