{
    "significant_genes": {
        "Variable": [
            "ABL2",
            "AKT2",
            "A1CF",
            "BRWD1-AS2",
            "ACSF2",
            "AAMP",
            "ADGRE2",
            "FAM47B",
            "ARMH3",
            "ABTB3",
            "C9orf50",
            "ACACA",
            "ABHD18",
            "NEUROD1",
            "ABHD11",
            "B3GNT9",
            "ARRDC4",
            "KCTD15",
            "ADAMTS9",
            "C12orf60",
            "LRFN2",
            "ACTN4",
            "ABCA17P",
            "ADARB1",
            "AADAT",
            "ANKH",
            "ATG4B",
            "CEACAM6",
            "CT55",
            "AHR",
            "CTSC",
            "CHD3",
            "OR7A17",
            "CCDC144BP",
            "CNIH4",
            "CALN1",
            "ATP5MC1",
            "AAAS",
            "AK1",
            "ADORA2A",
            "LSMEM2",
            "CFH",
            "DGKA",
            "PTPN23",
            "IER2",
            "HOXD1",
            "ABHD4",
            "COA1",
            "ATE1",
            "ARHGEF16",
            "BSG",
            "FANCD2OS",
            "HOXB6",
            "ASIC2",
            "CDH22",
            "AMN1",
            "H2AC8",
            "MIR4296",
            "ADAMTS5",
            "MSC",
            "ADTRP",
            "SH2D5",
            "BMPR1B",
            "TMEM54",
            "ADAM3A",
            "CPPED1",
            "AKAP3",
            "ACADL",
            "NEDD4",
            "BEND5",
            "BLTP3A",
            "CUL5",
            "LINC02909",
            "FGFR3",
            "AGAP11",
            "ADGRL3",
            "DEFB107A",
            "CFHR1",
            "MYO3B",
            "GOLGB1",
            "HELB",
            "FFAR2",
            "SCRN2",
            "CNTNAP1",
            "DCX",
            "ARHGAP24",
            "H2AC16",
            "ABCB7",
            "ARL3",
            "ADAP1",
            "OR10H2",
            "ARHGEF39",
            "SYNGR3",
            "GRP",
            "ELAPOR2",
            "ABCA8",
            "ASXL3",
            "OR51B6",
            "ANGEL2",
            "PDGFA",
            "DEFB126",
            "KCNQ1",
            "ADAM28",
            "BRICD5",
            "CHTF18",
            "PSORS1C3",
            "TBL1X",
            "ABCB11",
            "SLC38A10",
            "MEFV",
            "ABITRAM",
            "PITRM1-AS1",
            "SLC30A4",
            "COL17A1",
            "LRRC14",
            "FIBIN",
            "YWHAEP7",
            "ANGPTL7",
            "APOLD1",
            "AR",
            "ARF6",
            "IL12RB2",
            "KANSL1-AS1",
            "ID2B",
            "C1orf198",
            "ACSL4",
            "COMP",
            "APOA2",
            "NOXO1",
            "RP1L1",
            "LSS",
            "ADD3",
            "MEIOB",
            "ARL14",
            "AATK",
            "NFRKB",
            "OPN1SW",
            "ID2",
            "MBD6",
            "CEBPD",
            "ADAM8",
            "PLXNA3",
            "ATG9B",
            "DYM",
            "AHCTF1",
            "CRYGEP",
            "DAPP1",
            "BICDL1",
            "ACAN",
            "BCL11A",
            "POPDC3",
            "ERP44",
            "FBH1",
            "CADM2",
            "CDA",
            "GRIA2",
            "ACVR2B-AS1",
            "ABHD15",
            "CHKB",
            "C4orf17",
            "FCGR1A",
            "FZD8",
            "ANKRD40",
            "AGA",
            "TTC32",
            "TBX6",
            "GADL1",
            "BTBD17",
            "ACTN3",
            "NPC1L1",
            "IFRD1",
            "H2AP",
            "PLPPR1",
            "LHX2",
            "EFCAB3",
            "AMH",
            "FAM43B",
            "CDHR1",
            "TBC1D22A",
            "TRABD",
            "LARP6",
            "CTNNA2",
            "H2AB1",
            "H2BC11",
            "DHODH",
            "PPP1R1B",
            "SFRP4",
            "LRCH1",
            "CALD1",
            "EP300",
            "CELSR2",
            "MPHOSPH10",
            "AGBL1",
            "MTX2",
            "ASTE1",
            "CEP128",
            "FANCG",
            "ANXA1",
            "FUT3",
            "ACD",
            "CCNB2",
            "APOC3",
            "KRT80",
            "ANKRD20A8P",
            "PLEKHA4",
            "ABRA",
            "MTO1",
            "AVPI1",
            "ARHGEF2",
            "IQGAP3",
            "ANAPC11",
            "PHOSPHO1",
            "RSPO1",
            "ACOT8",
            "CS",
            "PTGES",
            "SPIDR",
            "LETMD1",
            "ABCA9",
            "RNF183",
            "MBOAT1",
            "MIER1",
            "NXNL2",
            "FAM181B",
            "KRTAP11-1",
            "HDC",
            "AGO3",
            "GGT8P",
            "AKAP9",
            "BCAS4",
            "ALS2CL",
            "NCAN",
            "UPF2",
            "BEAN1",
            "KRT81",
            "ABCB5",
            "RXFP2",
            "HDGF",
            "HIVEP3",
            "CEACAM5",
            "BATF3",
            "AGAP3",
            "DCT",
            "TBC1D10A",
            "MMEL1",
            "WNT9A",
            "KCNJ16",
            "CERS4",
            "EGFL6",
            "KANSL3",
            "ASB9",
            "EFNB1",
            "ARL8A",
            "GK3",
            "TNFRSF11B",
            "GPAT2",
            "AGAP6",
            "CCDC144A",
            "ENTREP2",
            "ACSS2",
            "CLK2",
            "ABCB9",
            "ALDH1L2",
            "ABI3",
            "NIBAN3",
            "KCNQ2",
            "BLM",
            "PRRT3-AS1",
            "COMMD9",
            "CASQ1",
            "ANKRD10",
            "AGRP",
            "MRM1",
            "CCDC91",
            "C2CD2L",
            "ABCC12",
            "WDR45",
            "ARF1P1",
            "HCN4",
            "DHRS9",
            "DNAJB5",
            "LYSMD1",
            "ADCK2",
            "TLK2",
            "H1-0",
            "MIR7-3HG",
            "ZNF33A",
            "ZNF136",
            "INSM1",
            "ACOT11",
            "SPRYD3",
            "APAF1",
            "CYP4F8",
            "ACSM3",
            "HYKK",
            "EVPL",
            "MIR4755",
            "PDLIM3",
            "C1QTNF12",
            "BLK",
            "ODAM",
            "ARFIP1",
            "RNU2-22P",
            "ADCY5",
            "C6orf52",
            "AMT",
            "TMPRSS11D",
            "DYSF",
            "KIAA1210",
            "SLC25A53",
            "AZGP1",
            "SH3TC1",
            "CACNA1A",
            "PRKAA2",
            "AADAC",
            "ARHGEF3",
            "SDR16C5",
            "IQCE",
            "AXIN1",
            "FAM131B",
            "MGAM",
            "IGLV1-36",
            "ABCB1",
            "AMPH",
            "PPOX",
            "ERICH4",
            "TYSND1",
            "ELOCP28",
            "B3GALT4",
            "NAPEPLD",
            "ALDH3A2",
            "SYT8",
            "GGT3P",
            "SGCG",
            "WFDC13",
            "ABCD4",
            "ZNF718",
            "ITGB3",
            "DEGS1",
            "HSD17B11",
            "OR7C2",
            "ADRA1A",
            "PRELID2",
            "ABTB2",
            "CHFR",
            "ZFP28",
            "ADGRA1",
            "AA06",
            "ARNT",
            "GH2",
            "ZDHHC24",
            "CIT",
            "MTSS1",
            "ECPAS",
            "C1orf35",
            "ABHD1",
            "RRP7BP",
            "JAK1",
            "ANAPC4",
            "ATOSA",
            "TUNAR",
            "VPS33B",
            "ADAM22",
            "C16orf89",
            "GLYCTK-AS1",
            "HKDC1",
            "KLHDC7A",
            "CA12",
            "HEATR1",
            "SLC25A3P1",
            "MBL1P",
            "NUP133",
            "PARVG",
            "AFAP1L1",
            "PTTG2",
            "MPZL3",
            "NTSR1",
            "AGAP2-AS1",
            "CLDN11",
            "MR1",
            "EIF3LP3",
            "UCKL1",
            "CDYL2",
            "PLA2G6",
            "VGLL1",
            "LARP1",
            "PRR5",
            "COL11A1",
            "PARVB",
            "RNF121",
            "VPS37D",
            "MARCHF8",
            "FDPS",
            "CRY2",
            "GABRD",
            "MATK",
            "CENPF",
            "OPA1",
            "PRKACG",
            "WDR19",
            "TMEM169",
            "ACBD6",
            "FKBP3",
            "KLHDC9",
            "ZNF597",
            "TRAV21",
            "GNPAT",
            "COL10A1",
            "APP",
            "AURKA",
            "CARD8",
            "TMUB2",
            "SYNJ2BP",
            "ABHD16B",
            "AKR1C3",
            "CAMLG",
            "CADM1",
            "H2AB2",
            "H2AB3"
        ],
        "Coefficient": [
            0.06727700267404639,
            0.06354739209387408,
            -0.039907342963437786,
            0.03967163009606877,
            0.03793275319177352,
            0.036597160952535394,
            0.03649420592733261,
            0.03401943376068838,
            0.03333631256216908,
            -0.03288850603515609,
            0.03276239937499764,
            0.029385942895982575,
            -0.029231404458045143,
            0.028516149801881063,
            0.02648283345837906,
            -0.02642319395026258,
            -0.026369097780857772,
            -0.02471612812304334,
            -0.024520667220355778,
            -0.024462579522739288,
            -0.02445765663956002,
            0.024181114842762426,
            0.02369830259045126,
            0.0236013066446879,
            -0.02214060760649734,
            -0.02206570921870795,
            0.02131158477396598,
            0.02130878300115203,
            -0.021018959814418228,
            -0.020762334352821148,
            -0.020507634703112836,
            0.020231652405410624,
            -0.01961702249879209,
            -0.019570678933429574,
            0.019482749843450074,
            -0.019416429347719397,
            0.019182952518073754,
            -0.0191569678134684,
            0.018549810128128133,
            0.01803920567142979,
            -0.017222620882941565,
            0.01717623515380792,
            0.01684043608936938,
            0.016757138175174175,
            -0.01666516152220059,
            -0.01661060169917425,
            0.016270688397193162,
            -0.015997813438629743,
            0.015741264156254785,
            -0.01564744694229967,
            -0.015532396243301065,
            -0.015112641722037716,
            -0.014806463481325912,
            -0.014400663548139323,
            -0.014202691574732324,
            -0.014121095026576446,
            -0.013983570728017805,
            0.013914297289988034,
            -0.013661783397091318,
            -0.013563822999692929,
            -0.013250303407678167,
            -0.013111925608932127,
            -0.01293596484863805,
            -0.01291502267698669,
            0.012876081479850551,
            -0.012631458353670888,
            -0.012473321213913575,
            -0.012170064157663717,
            -0.011930851887339618,
            -0.011845198418483187,
            -0.01171649008160788,
            -0.011454592231817759,
            -0.011360684640168548,
            -0.011282517821205047,
            0.011260667948744963,
            -0.011084425257413554,
            0.011038066006169288,
            0.010593903331289211,
            0.01032414057273199,
            0.010311942575036,
            0.010187164243679808,
            0.010104224728587935,
            0.010050083964723051,
            0.010033830935272693,
            -0.009936660672666436,
            0.009902497200295606,
            -0.009848753664991414,
            0.009820846619408647,
            0.009740573554013534,
            0.009505813088823681,
            -0.009486747782428695,
            0.00925157187828172,
            0.00921819813397498,
            0.009131137575292936,
            0.008714328851810314,
            -0.008559859902749985,
            0.008288216282367868,
            0.008284434314642443,
            0.008275316057080909,
            -0.008274174961550106,
            0.008270588970409573,
            -0.008076830026534787,
            -0.007936316013583732,
            0.007772369986575311,
            0.0077387502520659115,
            -0.007706063127169795,
            0.007459806514252923,
            -0.007342070573600325,
            0.007277839343853307,
            -0.007188019725653927,
            -0.007184408094926451,
            -0.007176915661282689,
            0.007066532149965169,
            0.006907654092345315,
            0.006858603476636245,
            0.0068270687924448055,
            -0.0067555004204254135,
            -0.0067333593825621854,
            0.006605576628769306,
            0.006554341312237758,
            0.006521085117423215,
            0.006406610308599131,
            -0.0062462524020739565,
            -0.006099959408542919,
            0.006080509919725302,
            -0.00605295357471308,
            0.006005075269572926,
            0.005961103137461334,
            0.0059495762710461446,
            -0.005867436223208087,
            0.005823217999482997,
            -0.005816461218328916,
            -0.005809793908913871,
            -0.005715738700473742,
            -0.005702413495903746,
            -0.005647131110764497,
            0.005592292985169371,
            -0.005559462250948803,
            0.005289767963364205,
            -0.005261738644630943,
            0.005231462311729012,
            0.005176860251616897,
            0.005130865765333528,
            0.005081521261740402,
            0.005079772566599927,
            -0.005029471530614489,
            0.004968874610593464,
            -0.004930937304216063,
            0.004924571392816028,
            0.004853041963361654,
            0.004803670580221941,
            0.004777343625149886,
            0.004727825894835726,
            0.004671248040408573,
            0.004666948803141356,
            -0.004559574891002544,
            0.004523415652389307,
            0.004481429263851611,
            0.004434219840547176,
            -0.004354613819039105,
            -0.004330924331355046,
            -0.004297073400315021,
            0.004233130313399975,
            -0.00421300150439301,
            0.004199313581749226,
            0.004192668362331942,
            -0.004156454164926985,
            -0.004150843511306991,
            0.004052844701082551,
            0.0040500703524118265,
            -0.004045043358632667,
            0.0040157499206894525,
            -0.003998939445732603,
            -0.0039669350942793434,
            -0.003863207308937547,
            0.003838739306547032,
            -0.003714321586455533,
            -0.003687781013992129,
            0.003618487862226252,
            0.0036127492409800295,
            0.003551463900753976,
            -0.003533768213474213,
            0.0035067723834018563,
            -0.00349896152186352,
            -0.003470120656253815,
            -0.0034619989850609035,
            0.003425403045453888,
            0.003407566205190944,
            0.003401474276540129,
            0.0033991817073370113,
            0.003361473943204393,
            -0.0032511490303461068,
            0.0031769923503184427,
            -0.003069077285272869,
            -0.0030418846030824415,
            0.003037502139373068,
            0.003027723690938571,
            -0.002973729458594153,
            0.002973479690395558,
            0.0029529223557405995,
            0.002888118134901572,
            0.002820659160683403,
            0.0028132629094564706,
            0.0028044852770967676,
            0.002781390057287019,
            -0.0027726463805783003,
            -0.0027715176068998587,
            0.0027708004255588064,
            0.0027705970797920598,
            0.0027209197052846094,
            0.0026865875822146717,
            -0.0026862571063951722,
            0.002560850467634954,
            0.0025429621235906565,
            0.0024859642004371203,
            0.002426481687444331,
            -0.0024224902749202734,
            0.0023927862233417384,
            -0.0023680230912465957,
            -0.0023441106449209655,
            0.00233449761039181,
            -0.0022449859442685116,
            0.0021884790164913635,
            -0.002162860566613733,
            0.0021616490112831544,
            -0.0021464432403207417,
            -0.002073307423582512,
            -0.0020514499716213584,
            0.002014512797069616,
            0.001990342698546894,
            0.0019876770358555162,
            0.0019753533600926692,
            0.001947554344211111,
            0.0019244915134465413,
            0.001894278956829519,
            -0.0018868886966943092,
            -0.0018819094156151198,
            0.0018733194095001886,
            -0.0018645428123465146,
            0.0018084819162916836,
            0.0017371969699199585,
            0.001705390492747639,
            0.001678642334609148,
            0.0016766015129983359,
            -0.0016748112388530396,
            -0.0016541764827202048,
            -0.0016329030155738545,
            -0.001622899170858974,
            0.0015609304897811914,
            0.001558549427340626,
            0.0015283751761896102,
            -0.0015001778256155994,
            0.0014947665393285005,
            0.0014168919654752449,
            -0.0014056465435476212,
            0.0013881314711272161,
            0.001381629127922491,
            -0.001373652378129391,
            -0.0013491970052479695,
            0.0012861437032052133,
            0.0012496349029778567,
            -0.0012389792786713857,
            0.001237566958063367,
            -0.0012304598967458563,
            0.0012007723974424925,
            -0.0011786405874523401,
            0.0011691600518307275,
            -0.001103394134461736,
            -0.0010830475273198858,
            0.001068340313781566,
            -0.001043984213708124,
            0.0010274939567875357,
            -0.0010016663806899227,
            -0.0009832269749425811,
            0.0009572411847067159,
            -0.00095608392732985,
            0.0009533807886996053,
            0.0009479877939041856,
            -0.0009376661858710647,
            0.0009308123013499274,
            -0.0009292738731100953,
            0.0008792463702363046,
            0.0008757767387015007,
            0.0008728337402038705,
            0.0008669045504972154,
            -0.0008637188906130968,
            0.0008553679256360934,
            -0.0008364180333008056,
            0.0008311627057263443,
            -0.0007885273795024899,
            0.0007846077112924674,
            0.0007359569173787284,
            0.0007341133494515431,
            -0.000710490866025459,
            0.0007096810169053127,
            0.0007043230317389448,
            -0.0006799027766494989,
            0.0006791420734957785,
            0.0006733861422407794,
            0.0006726643906063195,
            0.0006662177430802628,
            -0.000653972895268593,
            -0.0006308935113003369,
            0.0006307264606186801,
            -0.0006118312000791446,
            -0.0006023521952093899,
            0.0005914492097706943,
            -0.0005773200142975257,
            0.0005594147271752483,
            0.0005571233201950622,
            0.0005363410137459101,
            -0.00048730170358637323,
            0.0004811445058043823,
            -0.00046936882839710494,
            -0.00045459302406203827,
            -0.0004510879644869123,
            -0.00044817622923872994,
            0.00044351526840560336,
            0.00043789165648153123,
            -0.0004374934845066813,
            -0.0004314455430333577,
            0.0004159382930202093,
            -0.00041452134932829817,
            -0.00040806317106972513,
            0.0003990818037728386,
            -0.00039573936265410324,
            0.0003889454912557858,
            -0.0003774245193370953,
            0.00036795193869971614,
            -0.00034799812947510606,
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