{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "BCAP31",
            "BTK",
            "C4BPA",
            "C1R",
            "DEFB4A",
            "IRAK2",
            "CD40LG",
            "APP",
            "C1QB",
            "CCL8",
            "CXCR3",
            "B3GAT1",
            "ADGRE2",
            "LILRB5",
            "HLA-DQA1",
            "CCL15",
            "MAPK14",
            "EBI3",
            "FADD",
            "BCL2",
            "TP53",
            "CD59",
            "TLR3",
            "CIITA",
            "C3",
            "LTB4R",
            "HRAS",
            "HFE",
            "EGR2",
            "CCL20",
            "DEFB103A",
            "PTGS2",
            "CD9",
            "FYN",
            "PSMB5",
            "CR2",
            "CD86",
            "IL1R1",
            "DEFB103B",
            "FKBP5",
            "BST2",
            "CXCR2",
            "BATF",
            "CTNNB1",
            "CRADD",
            "S1PR1",
            "PTAFR",
            "IKZF1",
            "CCR8",
            "IL4R",
            "CARD9",
            "NFATC2",
            "CCND3",
            "CD14",
            "IL7",
            "CD53",
            "MAPKAPK2",
            "SLC2A1",
            "MALT1",
            "MBP",
            "NT5E",
            "CCL5",
            "ATG16L1",
            "CCL3",
            "IL6",
            "KLRC3",
            "FCAR",
            "FOXP3",
            "ATG12",
            "ABL1",
            "FAS",
            "CD79B",
            "IRF7",
            "CCL13",
            "POLR1G",
            "CD19",
            "IL17A",
            "IGF2R",
            "CD46",
            "LTB4R2",
            "BCL3",
            "FN1",
            "CD80",
            "ATG10",
            "IRGM",
            "TNFSF11",
            "LCP2",
            "CFI",
            "CXCL11",
            "SELE",
            "LIF",
            "CFD",
            "AIRE",
            "CCL2",
            "NOTCH2",
            "PSMC2",
            "MAP4K4",
            "SPP1",
            "FCER1A",
            "ITGA5",
            "CCL19",
            "IL13RA1",
            "MUC1",
            "KLRA1P",
            "CFH",
            "SELPLG",
            "PDCD1",
            "CCL22",
            "CCRL2",
            "MX1",
            "RAG2",
            "HLA-DRB3",
            "ZBTB16",
            "CD160",
            "CD36",
            "EDNRB",
            "DEFB1",
            "NOD2",
            "AICDA",
            "IL1RN",
            "FCGR2B",
            "IL32",
            "ATG7",
            "IL10",
            "ACKR4",
            "IL26",
            "NLRP3",
            "POU2F2",
            "BCL10",
            "EGR1",
            "GZMK",
            "IL1RAP",
            "CFB",
            "IFI16",
            "MAPK11",
            "IL22",
            "CLU",
            "BLNK",
            "ITGA2B",
            "IL4",
            "CCL4",
            "IL21R",
            "TNFSF15",
            "SLAMF1",
            "IL16",
            "TLR4",
            "TOLLIP",
            "RAG1",
            "IRAK4",
            "ITLN2",
            "CCL16",
            "CXCL8",
            "CD1D",
            "CD4",
            "CASP8",
            "STAT4",
            "PDCD2",
            "MSR1",
            "TNFSF13B",
            "CD1A",
            "CUL9",
            "SLAMF6",
            "IL3",
            "IFI35",
            "TCF7",
            "BTLA",
            "TNFSF8",
            "B2M",
            "GP1BB",
            "IL1B",
            "CD7",
            "BAX",
            "CLEC6A",
            "IL15",
            "HLA-C",
            "IL21",
            "CXCL1",
            "TIRAP",
            "C1QA",
            "NCAM1",
            "IL7R",
            "KLRG1",
            "TGFBI",
            "IL6R",
            "IRF4",
            "CD274",
            "MME",
            "KCNJ2",
            "CD163",
            "CLEC4E",
            "IRF3",
            "IRAK1",
            "HLA-DMB",
            "ENTPD1",
            "PDCD1LG2",
            "TNFRSF17",
            "CX3CR1",
            "CCR10",
            "PLAU",
            "CD70",
            "PSMB7",
            "CD48",
            "TAPBP",
            "IL10RA",
            "CCR1",
            "PRKCD",
            "CSF2",
            "TLR1",
            "IRF5",
            "CCL23",
            "CCR6",
            "CCR2",
            "CD8B",
            "PTPN2",
            "TCF4",
            "PAX5",
            "CD58",
            "ITGA4",
            "CLEC5A",
            "TRAF1",
            "TAGAP",
            "TNFRSF9",
            "TLR9",
            "IFNB1",
            "CXCR6",
            "IL2RA",
            "KLRG2",
            "UBE2L3",
            "PDGFB",
            "ITGB1",
            "BST1",
            "LCK",
            "MS4A1",
            "HAVCR2",
            "IKBKE",
            "HLA-DPA1",
            "STAT3",
            "TNFRSF10C",
            "IFNL1",
            "CTSC",
            "CD164",
            "IFNA2",
            "CD8A",
            "ICAM1",
            "IL27",
            "IL12B",
            "TRAF4",
            "ITGB2",
            "CSF1",
            "PLA2G2E",
            "CDKN1A",
            "ICAM3",
            "MYD88",
            "PML",
            "IL6ST",
            "CD96",
            "IL2RG",
            "STAT1",
            "CSF2RB",
            "TNFSF12",
            "TLR2",
            "STAT5A",
            "C5",
            "CEACAM6",
            "MIF",
            "IL20",
            "C1QBP",
            "C7",
            "ARHGDIB",
            "NFATC1",
            "BID",
            "ELP1",
            "C6",
            "KIT",
            "IFNAR1",
            "IL17F",
            "ADA",
            "ARG2",
            "IL23R",
            "CD28",
            "CXCL13",
            "CD276",
            "CXCL12",
            "RELB",
            "ITGAL",
            "KLRC1",
            "IL11RA",
            "XCL1",
            "CD40",
            "IFIH1",
            "IL1RL2",
            "SMAD5",
            "PTGER4",
            "HAMP",
            "TGFBR1",
            "ITGAM",
            "CCL7",
            "PRDM1",
            "CCL26",
            "VCAM1",
            "ABCB1",
            "CD55",
            "CD3D",
            "CD81",
            "CD74",
            "CASP10",
            "LILRB2",
            "NOTCH1",
            "CX3CL1",
            "MRC1",
            "MR1",
            "TLR5",
            "SYK",
            "GBP5",
            "IL2RB",
            "TLR8",
            "CEBPB",
            "S100A8",
            "LAG3",
            "LITAF",
            "LTA",
            "HLA-A",
            "JAK3",
            "TNFRSF1B",
            "CXCL2",
            "KLRB1",
            "CD2",
            "TNFRSF11A",
            "PRF1",
            "CD99",
            "NFKBIZ",
            "CR1",
            "C1S",
            "HLA-DPB1",
            "FCGR2A",
            "LAIR1",
            "PLAUR",
            "KIR3DL1",
            "CCL11",
            "FCGRT",
            "TFRC",
            "IKBKB",
            "XCR1",
            "IRAK3",
            "LILRA6",
            "ARG1",
            "BCL6",
            "CD34",
            "IFNL2",
            "CCL24",
            "THY1",
            "CCR5",
            "CEACAM8",
            "PSMD7",
            "LILRA1",
            "NOD1",
            "CD247",
            "ICOS",
            "CASP2",
            "SERPING1",
            "CD79A",
            "TBK1",
            "SOCS3",
            "NFKB2",
            "STAT6",
            "LY96",
            "TGFBR2",
            "CDH5",
            "ILF3",
            "NCF4",
            "IFIT2",
            "PSMB9",
            "CD83",
            "KLRF1",
            "IL5",
            "HLA-DOB",
            "KIR3DL3",
            "MAPK1",
            "HLA-DMA",
            "TNFSF4",
            "MAF",
            "PDGFRB",
            "TRAF6",
            "CSF3R",
            "TYK2",
            "RTRAF",
            "CD27",
            "GPI",
            "HLA-B",
            "TIGIT",
            "NCR1",
            "IL1A",
            "ICOSLG",
            "MASP2",
            "LILRB1",
            "HLA-DRB1",
            "CD44",
            "CCL18",
            "ICAM4",
            "CMKLR1",
            "IL12A",
            "TNFRSF13B",
            "GATA3",
            "ICAM5",
            "GBP1",
            "PTPN22",
            "IL18RAP",
            "CFP",
            "CD5",
            "TNFSF10",
            "IL1R2",
            "IRF8",
            "ITGA6",
            "IFNGR1",
            "CD24",
            "IL13",
            "C8B",
            "TNFRSF14",
            "ITGAE",
            "CXCL9",
            "STAT5B",
            "TNFRSF8",
            "IKZF3",
            "LTBR",
            "LTF",
            "CLEC7A",
            "IL9",
            "C8G",
            "CYBB",
            "ITGAX",
            "LILRA3",
            "IDO1",
            "LAMP3",
            "PTK2",
            "NOS2",
            "ITLN1",
            "DPP4",
            "PLAAT4",
            "TNF",
            "ICAM2",
            "RORC",
            "GZMB",
            "CD82",
            "SELL",
            "CLEC4A",
            "CD6",
            "HLA-DQB1",
            "TRAF2",
            "LILRA2",
            "C9",
            "RAF1",
            "CXCL10",
            "KLRD1",
            "LEF1",
            "RUNX1",
            "TRAF3",
            "CXCR4",
            "SLAMF7",
            "SOCS1",
            "LILRB3",
            "IRF1",
            "KLRC4",
            "JAK1",
            "CHUK",
            "IL18",
            "VTN",
            "TAL1",
            "LGALS3",
            "CSF1R",
            "CTSG",
            "XBP1",
            "TAP2",
            "IKZF2",
            "KLRF2",
            "HLA-DRA",
            "SH2D1A",
            "IL17B",
            "PPARG",
            "PTPN6",
            "CAMP",
            "IL19",
            "TAP1",
            "IL18R1",
            "ATM",
            "GNLY",
            "CASP3",
            "GZMA",
            "PIGR",
            "PPBP",
            "NFKBIA",
            "LILRA4",
            "MCL1",
            "TICAM1",
            "PSMB10",
            "JAK2",
            "KLRK1",
            "MBL2",
            "AHR",
            "NFATC3",
            "GFI1",
            "KLRC2",
            "MAP4K2",
            "FCER1G",
            "NFIL3",
            "TNFAIP6",
            "LILRA5",
            "GPR183",
            "IL22RA2",
            "CCR7",
            "ZEB1",
            "TRAF5",
            "IL23A",
            "DUSP4",
            "CD244",
            "IKBKG",
            "C2",
            "MAP4K1",
            "IFITM1",
            "STAT2",
            "S100A9",
            "SRC",
            "PSMB8",
            "CD3E",
            "IFNG",
            "CXCR1",
            "CTSS",
            "ETS1",
            "KIR3DL2",
            "TNFAIP3",
            "LILRB4",
            "MARCO",
            "MASP1",
            "TLR7",
            "C8A",
            "ZAP70",
            "CEACAM1",
            "STING1",
            "CISH",
            "PLA2G2A",
            "IL12RB1",
            "SKI",
            "NFKB1",
            "CD209",
            "EOMES",
            "PECAM1",
            "IFNAR2",
            "TGFB1",
            "SIGIRR",
            "SMAD3",
            "IL2",
            "PYCARD",
            "RELA",
            "TNFRSF13C",
            "IL1RL1",
            "TNFRSF4",
            "CASP1"
        ],
        "Coefficient": [
            0.1217208095584659,
            -0.08729757049253396,
            0.08018261420045987,
            0.07955721358933669,
            -0.07693790602523792,
            -0.07277532717480907,
            0.07215477008513582,
            -0.06926420600258924,
            -0.06923783062665645,
            0.06868808921438976,
            0.06801177430132682,
            0.06625137225487182,
            -0.06512528814738529,
            0.06391651538626793,
            0.0638555466584569,
            -0.06322766836015462,
            -0.0626443693356834,
            0.061960755669361545,
            0.06189110144045331,
            -0.0616543209989285,
            0.06119047399882435,
            -0.05872334824158377,
            0.058640611013699676,
            -0.057975270455217706,
            -0.055459082839986976,
            0.05530438608777182,
            0.05393617426183428,
            0.053915063201075066,
            0.053533994389867834,
            0.05331637274150385,
            -0.05305935708980993,
            -0.0525699258100021,
            -0.05201631248656165,
            0.05153639146684544,
            0.050861292991885014,
            -0.05044683705027886,
            0.050389495300721926,
            0.050003662874561615,
            0.0499192730515808,
            -0.04945743166322103,
            0.04943613921226821,
            0.048323277162806114,
            -0.04752492754104108,
            0.04746841657218986,
            0.04746453943364488,
            0.04738006085656431,
            -0.047331060035712635,
            -0.046735997051380616,
            -0.046166583856505676,
            0.04595503497352006,
            -0.045108452276407786,
            0.04509177120598333,
            0.04475733992059876,
            -0.04430676692767666,
            -0.04425061638121146,
            0.043860132650780106,
            0.04364742088477962,
            -0.043275190480863375,
            0.04316038389143184,
            0.04308175882022861,
            0.04305534377844253,
            -0.04229488424734663,
            -0.042187529006924136,
            0.04185203971203995,
            0.04181342616977386,
            -0.04167248912920106,
            -0.04163160751281466,
            0.04159852010543871,
            0.04126541200217658,
            -0.04071499618228703,
            -0.04019179177966141,
            0.04006008891172135,
            -0.039963547493513295,
            0.03960901879531568,
            -0.03933875785666663,
            0.03914226713830771,
            -0.03872699865213287,
            0.038612621756492924,
            0.03853113389690566,
            -0.03850703383372398,
            -0.038328743706311626,
            -0.03800501042724266,
            0.03797763504051663,
            -0.03700253062175539,
            0.036206240521758096,
            -0.036027694437541044,
            0.03589492137079164,
            0.03578072887530838,
            -0.03531312497858144,
            -0.03518465137180694,
            0.03465507915965,
            -0.0346517099252106,
            -0.034557483232593555,
            0.034290688394570314,
            0.03413788419765408,
            -0.033823959460256715,
            0.03382320202571057,
            0.033564863382734476,
            -0.03343523227329256,
            0.03338202325552999,
            0.03333698293517807,
            -0.033236752611619444,
            0.033142781959532505,
            0.03304469820155834,
            0.03279149480596944,
            -0.032678888589177196,
            0.03255231896293983,
            0.03231444521805544,
            0.03211687744078256,
            0.031907581012432545,
            0.03183359643216974,
            0.031530161975746346,
            0.031525130575062996,
            -0.03129241082844362,
            -0.03099779179685633,
            -0.030953398791640722,
            0.030864044179633426,
            -0.030775981108783598,
            0.030371733718124825,
            -0.03028018359764752,
            -0.030053572169468207,
            -0.030014602415285436,
            0.02998185124319837,
            -0.029977205086393423,
            0.029911917366750473,
            0.0298334532726482,
            -0.029810980745186923,
            0.02945793514388486,
            -0.029384499979445748,
            -0.029276365227183777,
            -0.028844751846673195,
            -0.028529792257921096,
            0.02812841714728873,
            -0.02811250337680461,
            -0.028110228811372904,
            -0.027525989249373328,
            0.027324689970401647,
            0.027251097747320856,
            0.02714303324873207,
            -0.027104170700030624,
            0.026824515915101817,
            0.026807830191506822,
            0.026764392869250652,
            -0.02671834220299505,
            0.026666263076081016,
            0.026558683477882525,
            0.026481873650711685,
            0.02646268929118365,
            -0.026285209224663795,
            0.0262408353032999,
            0.02608279409634596,
            -0.026022477870981713,
            -0.026003338207050874,
            -0.02590400200478795,
            0.025847486688703233,
            0.02578361518296197,
            -0.02578147789294312,
            0.025541165468622593,
            -0.025518320313710353,
            -0.025452007835537093,
            -0.025443036917098958,
            -0.02533053418171198,
            -0.025090383349486316,
            0.02506850434804097,
            0.02496934789254304,
            -0.024920846969975857,
            0.024916591801335423,
            0.024812129399705417,
            -0.02479749042273446,
            0.024425276428147673,
            -0.024350947425779392,
            -0.024199811035349263,
            -0.024165722966824822,
            -0.02414072972623873,
            0.024000926120490304,
            -0.0239980681918254,
            -0.023846610215430213,
            -0.023833963027024316,
            -0.023812416292611858,
            0.023751277605982488,
            -0.023711496457755932,
            -0.02367243178548548,
            -0.023631247034420034,
            -0.023325377333346723,
            -0.023273969083488732,
            0.023245864580372314,
            0.023009506394312398,
            0.022962830922616854,
            -0.022938133102594894,
            -0.02292650833871645,
            -0.02289706304877019,
            0.022884639626610977,
            0.02284320885414255,
            0.022735356108419803,
            0.022634336589141258,
            0.022481863866189344,
            -0.022471272734726818,
            0.022398377064771144,
            0.022391088138757505,
            -0.022045597884065214,
            -0.022024166739734577,
            -0.02186317391144993,
            0.021827804839632377,
            0.021755534150021363,
            -0.021631040742156972,
            0.021622979235903284,
            0.02161802643646465,
            0.021520698060732167,
            -0.02149539012559077,
            0.021386145327805008,
            -0.02136574659469419,
            -0.021353894772172376,
            -0.021203669486677377,
            -0.02120341227311337,
            -0.021163317297212915,
            0.021142517489661172,
            0.02106927572508427,
            -0.02100112721485502,
            -0.02083577949262698,
            -0.02076654464167784,
            -0.020662816249622004,
            -0.02063238975278444,
            -0.02051642435865247,
            -0.02039037702015577,
            -0.02029663549871912,
            0.020222098871086593,
            -0.020204617748212292,
            -0.020202378077844738,
            -0.020163635344427097,
            0.019910298136197803,
            -0.019836024049974796,
            0.019799191738447658,
            0.019751939848865186,
            0.01962550270850664,
            0.019608735133983562,
            -0.01957771994756006,
            -0.01956940669357447,
            -0.019529913299551786,
            -0.019440085130534353,
            -0.019430920990516496,
            -0.01939596715827585,
            0.019360754530477614,
            0.019276870148592595,
            -0.01924462476162228,
            -0.019238398774622172,
            -0.019159738589664167,
            0.01909695098247966,
            -0.01891332061169219,
            0.018810107365181034,
            -0.018794965418893753,
            0.018769333841500313,
            -0.018748826743830452,
            0.01867691171445121,
            -0.018672185970134755,
            -0.018663012754457878,
            0.01866278019435301,
            0.018652564713851197,
            -0.01857966272730963,
            -0.01857372233171059,
            0.018480903737638953,
            0.018434977765138104,
            0.018387457195086238,
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