{
    "significant_genes": {
        "Variable": [
            "TAMALIN-AS1",
            "RASL10A",
            "PPEF1",
            "RANGAP1",
            "PCOLCE-AS1",
            "ODAPH",
            "DHRS2",
            "NEUROG3",
            "HCN1",
            "MGC2889",
            "FOXS1",
            "PPP4R4",
            "A4GALT",
            "BNIPL",
            "TRHR",
            "PNMA8B",
            "IZUMO2",
            "GHRHR",
            "CARD18",
            "EQTN",
            "OR11A1",
            "SPRY2",
            "TBX5",
            "USP29",
            "JAKMIP1",
            "KRT24",
            "NALCN",
            "KCNV2",
            "FAM215A",
            "FZD9",
            "CFAP206",
            "OR1C1",
            "PKD2L2",
            "CDH9",
            "MEG9",
            "CFAP95",
            "SPACA7",
            "GDNF",
            "THEM5",
            "GUSBP5",
            "GSX2",
            "KCNA4",
            "PNMA6A",
            "PLCD3",
            "ATP6V1G2",
            "FBXL9P",
            "TMCO5B",
            "SSMEM1",
            "RNF212B",
            "PPIEL",
            "AHRR",
            "CARF",
            "SZT2",
            "GLRA2",
            "ZNF366",
            "GTF2F2",
            "CCDC168",
            "CNR2",
            "KLHDC8A",
            "SOHLH2",
            "DENND10",
            "TP53TG5",
            "PLA2G1B",
            "PCDHB18P",
            "ARHGAP39",
            "CSH1",
            "LEPR",
            "PAX2",
            "ZNF544",
            "NT5C1A",
            "MPIG6B",
            "HECW1-IT1",
            "DAOA-AS1",
            "ANP32D",
            "AP5B1",
            "DLX6",
            "MRNIP",
            "WWTR1-AS1",
            "ZSWIM2",
            "CYP24A1",
            "TRIM71",
            "FREY1",
            "IMPG2",
            "SLC25A21",
            "GRK6",
            "TRPC3",
            "CD300C",
            "OR2A4",
            "GJD2",
            "ADCY1",
            "CSN3",
            "SPATA25",
            "PTPRT",
            "ADGRD1",
            "DEFB126",
            "TLCD5",
            "LMO1",
            "GPR75",
            "CIMIP2A",
            "LEMD1",
            "MEF2C-AS1",
            "ABHD1",
            "POLR1HASP",
            "PTPRG-AS1",
            "FAM241B",
            "TANGO6",
            "GABRA4",
            "UBASH3B",
            "WFIKKN2",
            "CDY1",
            "OR51B5",
            "GNA14-AS1",
            "GINS4",
            "LIPJ",
            "SLC30A2",
            "PTH2R",
            "DGCR6L",
            "SIM2",
            "CRX",
            "ZYG11B",
            "IQCD",
            "SAXO5",
            "ABCB9",
            "CHRNE",
            "MIR34A",
            "CEP131",
            "UBAP1L",
            "PROX2",
            "RNF152",
            "H4C13",
            "CAPN10",
            "TEX22",
            "CCDC148",
            "WDR97",
            "SLC35G3",
            "IL25",
            "HERC6",
            "CALHM1",
            "FUT1",
            "NTN5",
            "HMX1",
            "MAPK8IP2",
            "LINC02870",
            "DIRC1",
            "TAS2R10",
            "NRG1",
            "CIMIP4",
            "MAGEB4",
            "STX1B",
            "KRTAP1-5",
            "KRT32",
            "LINC02909",
            "LIPI",
            "KCNH3",
            "RPS10P7",
            "CCDC185",
            "PGLYRP2",
            "OLAH",
            "PCDHGA9",
            "IKBKG",
            "H2BC13",
            "CATR1",
            "SFTA3",
            "CCN6",
            "PYCARD-AS1",
            "IBA57-DT",
            "GABRG2",
            "KRTAP9-9",
            "FRRS1",
            "ATXN3L",
            "ZNF26",
            "LAIR2",
            "TSSK6",
            "DEFB108B",
            "ZMYND12",
            "LINC02878",
            "LHFPL4",
            "C12orf54",
            "EGFEM1P",
            "TSPAN15",
            "GALNT18",
            "BEX5",
            "ATP13A5",
            "PNRC1",
            "CCNA1",
            "PDZD9",
            "DYNLT5",
            "TMCO5A",
            "ITGBL1",
            "TMLHE",
            "DMRT2",
            "LIPC",
            "UGT2B15",
            "IL17A",
            "MPP4",
            "ATP6V1E1",
            "RFPL1S",
            "CCDC42",
            "TBRG4",
            "FAM53A",
            "FAM9C",
            "CLN5",
            "PPM1N",
            "SP3P",
            "CPLX3",
            "CCDC26",
            "CACNB3",
            "KCTD4",
            "ZAN",
            "GABRB1",
            "CRCT1",
            "CDNF",
            "OR7A10",
            "DCAF4L2",
            "LIM2",
            "DBIL5P",
            "NTRK3-AS1",
            "OR10H3",
            "NBR2",
            "ITGA2B",
            "NOG",
            "DIRAS1",
            "IFNA14",
            "DEUP1",
            "DGCR11",
            "MS4A5",
            "ADAM2",
            "NPIPB15",
            "PLD6",
            "FGFRL1",
            "CARS1-AS1",
            "MAGEA11",
            "C4orf17",
            "MT3",
            "FAM171A2",
            "DAO",
            "GJA3",
            "DLGAP1",
            "FIGLA",
            "SPATS1",
            "NFYC-AS1",
            "NAV2-AS5",
            "IQCF4P",
            "LAMB2P1",
            "MAP3K7CL",
            "CYP11B1",
            "ZNF208",
            "TMEM79",
            "PCDHAC2",
            "GPR61",
            "RNF185-AS1",
            "PLA2G3",
            "FAM230B",
            "ATPAF2",
            "CEP72",
            "HAGLROS",
            "ATP1B4",
            "FAM66D",
            "PDX1",
            "LHX9",
            "OR1D2",
            "CETN1",
            "KCNK13",
            "C2CD6",
            "FGG",
            "DCDC2",
            "SLC6A5",
            "TAAR9",
            "CRPPA-AS1",
            "HARBI1",
            "METTL21C",
            "MIA",
            "IFNA4",
            "LENG9",
            "PLGLB2",
            "NACA4P",
            "PTTG2",
            "CFAP52",
            "ZNF257",
            "PAX9",
            "TOE1",
            "KEL",
            "DLEU7-AS1",
            "PCDHGC3",
            "HTR7",
            "CBY3",
            "ZMYND10",
            "LINC01587",
            "OPN1SW",
            "CCDC17",
            "FRRS1L",
            "SPX",
            "ZNF71",
            "CLEC4G",
            "RBFADN",
            "FGB",
            "GPR32",
            "CNPY1",
            "NXNL2",
            "SPRY4",
            "ZFR2",
            "GDF5",
            "CLCNKB",
            "ELOVL3",
            "OR5P3",
            "CACNA2D2",
            "HAL",
            "KRTAP5-9",
            "NUP210L",
            "ADAD2",
            "ACSBG1",
            "PAQR9",
            "CCDC78",
            "ITPR1-DT",
            "PLPPR1",
            "STAB2",
            "CSN1S1",
            "SH3GL1P1",
            "MAPKAP1",
            "IZUMO1",
            "LINC02209",
            "POU4F3",
            "CFAP161",
            "POU3F3",
            "DNAH17",
            "PKDREJ",
            "NTNG2",
            "VASH2",
            "TAF1L",
            "RHOV",
            "ROR1-AS1",
            "FGF4",
            "FGF11",
            "KIF19",
            "TTC23L",
            "APLN",
            "GJA8",
            "MKS1",
            "BBS5",
            "PSG11",
            "GLB1L3",
            "TBC1D21",
            "CRY1",
            "AURKC",
            "CRELD1",
            "ANKUB1",
            "PLEKHG7",
            "EN1",
            "OR51I2",
            "SMG7-AS1",
            "MUTYH",
            "CLRN1",
            "ZACN",
            "ZNF683",
            "GSTT2",
            "NDUFV1-DT",
            "FAM131B",
            "SPAG8",
            "REDIC1",
            "XRRA1",
            "RHBDL2",
            "GPR135",
            "SLX9",
            "SSX1",
            "CFAP20DC",
            "KRBA1",
            "BEST2",
            "PIGM",
            "ZNF17",
            "AMBN",
            "AGER",
            "OOSP2",
            "SLC12A5",
            "TMEM235",
            "FAM187B",
            "HEMGN",
            "MAPK14",
            "DDX31",
            "ATP1A3",
            "IL1RAPL2",
            "FRY-AS1",
            "PGBD5",
            "TMEM108",
            "GBX2",
            "NRSN1",
            "HOXC-AS3",
            "IFNA1",
            "YWHAQ",
            "IMPG1",
            "CCDC70",
            "ANKRD33B",
            "FLJ37201",
            "CYTL1",
            "SSTR4",
            "GCM1",
            "PRDM16",
            "CEP89",
            "HOTAIR",
            "PRR3",
            "MAP1S",
            "C10orf55",
            "ZPBP2",
            "FAM83C-AS1",
            "SLIT2-IT1",
            "HYPK",
            "PIEZO2",
            "VSNL1",
            "S1PR5",
            "LINC01590",
            "C8orf48",
            "PCDH11X",
            "KRT37",
            "OVCH1-AS1",
            "PAGE5",
            "PHETA2",
            "C14orf180",
            "FAM167B",
            "ITIH4",
            "PACS2",
            "FFAR1",
            "TSPEAR-AS2",
            "COL20A1",
            "TKTL1",
            "OR8B8",
            "SYCP2L",
            "SYBU",
            "TUNAR",
            "LINC01600",
            "XCR1",
            "WBP2NL",
            "C9orf50",
            "AIRE",
            "CCSER1",
            "FAM230C",
            "MAMDC2-AS1",
            "ZNF334",
            "CHAC1",
            "NDRG4",
            "SMYD3",
            "DEFB119",
            "CRTAC1",
            "HCG9",
            "HS3ST5",
            "KCNMB3",
            "CFAP126",
            "ZNF718",
            "MYOZ1",
            "CLSTN2-AS1",
            "FOXJ1",
            "H1-1",
            "BRS3",
            "IRF9",
            "NLRP4",
            "KLHL11",
            "PATE2",
            "SNTN",
            "TARDBP",
            "HMBOX1",
            "SLIT1",
            "USP49",
            "SDR9C7",
            "SCARF1",
            "ARHGAP36",
            "CNTNAP3",
            "ULK4",
            "FLJ30679",
            "IQCH",
            "SLC29A4",
            "MAPK15",
            "KLF1",
            "FLJ42627",
            "CHST13",
            "RETN",
            "KCNK15",
            "PMCHL1",
            "DYNLRB2",
            "BRINP1",
            "ZNF333",
            "FUT9",
            "PAQR6",
            "CITED1",
            "NT5M",
            "ANGPTL3",
            "GBP6",
            "UTF1",
            "ADAMTS6",
            "ATOH8",
            "LOXHD1",
            "KRTAP8-1",
            "SPHKAP",
            "CT83",
            "OVGP1",
            "PAXBP1-AS1",
            "WHRN",
            "PRTG",
            "GHET1",
            "PROC",
            "AACSP1",
            "CYP4F29P",
            "NBPF3",
            "EGFLAM-AS4",
            "C17orf50",
            "ACSM5",
            "LINC01549",
            "HPCAL4",
            "LINC02905",
            "ATRNL1",
            "IAPP",
            "SPACA1",
            "ESX1",
            "SRPK3",
            "GLYATL1",
            "SMTNL1",
            "TFRC",
            "ZIC2",
            "ANGEL1",
            "CDH16",
            "ZNF543",
            "INSYN2A",
            "HTN3",
            "ZNF618",
            "KIAA0319",
            "RAD51D",
            "SLC32A1",
            "VENTXP1",
            "UBQLN3",
            "PAX1",
            "DCSTAMP",
            "SENP5",
            "TRIM50",
            "CNKSR2",
            "GALR1",
            "KRT13",
            "CATSPER3",
            "WIF1",
            "CBX3P2",
            "SPMAP2",
            "CAV3",
            "TAAR3P",
            "GGN",
            "RTP1",
            "UPP2",
            "TMEM121B",
            "CDKAL1",
            "OR10J1",
            "ZNF429",
            "PAK6-AS1",
            "C2orf81",
            "CALY",
            "USP26",
            "IFNA21",
            "DCTN1-AS1",
            "MYO1H",
            "ARPP21",
            "DUS3L",
            "SCGB3A2",
            "FRS3",
            "PKN3",
            "VWA5B1",
            "APOBEC3F",
            "SGCZ",
            "WDR53",
            "PXYLP1",
            "NSUN4",
            "OR10A3",
            "CTAGE11P",
            "SLC5A8",
            "STARD7-AS1",
            "CC2D2B",
            "MPV17L2",
            "UCP3",
            "TTLL9",
            "CPNE9",
            "KCNA6",
            "KMT5A",
            "MDGA1",
            "ZNF682",
            "KIAA1549",
            "ZC3H6",
            "SCN4A",
            "ADGRG2",
            "SNHG22",
            "OPRD1"
        ],
        "Coefficient": [
            1.9842183110466043,
            -1.953822190784244,
            1.86284280422653,
            -1.7284505350471349,
            -1.7067619106780605,
            1.6897143406414523,
            1.6787212284927722,
            -1.6651947574811665,
            1.5744187313877873,
            1.5625321654563522,
            -1.5332759129607467,
            1.5132059986227313,
            -1.511667586604479,
            -1.4990376520566262,
            -1.4841201292579569,
            1.4710489837091745,
            -1.4463900514736132,
            1.4043796029764264,
            -1.4027542516424414,
            1.4015804252058297,
            1.3430581581793746,
            -1.3316328992185595,
            1.2848964694284468,
            -1.2546843671427115,
            1.2497651608624267,
            -1.19980272051272,
            1.1972805881854525,
            -1.1969523909441322,
            1.168856687486268,
            -1.143073806650875,
            -1.124434093710051,
            1.1157891264429898,
            1.092894982757807,
            1.0857520944240775,
            1.0799029696564795,
            1.0778812684487455,
            1.0662281028319902,
            -1.0530471924127462,
            -1.0470435870987393,
            -1.037548799536291,
            1.0340520480229467,
            1.0273677310830487,
            1.005195393348519,
            1.002578936049695,
            -1.0008258998332482,
            -0.999548534597241,
            -0.9987916756020716,
            0.9965202147759195,
            0.989082071814266,
            -0.9707299417556123,
            -0.9427293512801788,
            -0.937009247092851,
            0.9342210536338863,
            -0.9318328697657965,
            -0.9207701512974287,
            0.9154410150321335,
            0.9104218722341062,
            0.9052414704238544,
            -0.9050998736814518,
            -0.8933097459766675,
            -0.8912308301860038,
            0.88043773675416,
            -0.8793547257790698,
            0.8745703519147652,
            0.8628818606187003,
            0.8430367890549357,
            0.8405988612069237,
            0.8308837275358048,
            -0.809883357610751,
            0.7981479728905435,
            -0.791112422747086,
            -0.7899009301367667,
            -0.7885692183624406,
            0.7841807358139927,
            0.7820883804418884,
            -0.7763350994822797,
            0.7750484437883445,
            0.7701124831601788,
            0.752091186487404,
            0.7502607222373026,
            -0.7487385170764268,
            -0.7483413955078362,
            -0.7315398339185964,
            -0.7306456622110578,
            -0.7294620978290871,
            0.7274997314314047,
            0.7265428580492138,
            0.7252939388220364,
            -0.720511677999708,
            0.7186211510149931,
            -0.713426365816944,
            -0.7090206954593739,
            0.7061110053155543,
            0.6866426964618079,
            0.6853885106150623,
            -0.6811846701133358,
            0.680708562209231,
            -0.6779490435391924,
            0.668618425777104,
            -0.6675572937298322,
            0.6662150465905391,
            -0.6650497503758692,
            -0.6607486082061651,
            -0.6591650010218335,
            -0.653599995200673,
            0.6523726431004517,
            0.6484886569115951,
            -0.6348010203089574,
            -0.6337786664310141,
            -0.6322940439558916,
            0.6279467895647077,
            0.6273324887781636,
            -0.6225138575053973,
            0.6209157527127515,
            -0.6200940561924128,
            0.6085487694494021,
            0.6083343644864277,
            -0.6079818626423592,
            0.6053316805575611,
            -0.6051981810991194,
            -0.6049975135721173,
            0.6019964297105281,
            -0.5959097695671078,
            0.5945683859120025,
            0.594565206724882,
            0.593356476140407,
            -0.5923292340935136,
            -0.5913533279831487,
            -0.5886766008980064,
            0.5854073931283428,
            -0.585008955500442,
            -0.5838832764379408,
            0.5815038795163416,
            -0.5808066865103171,
            0.5803976739861691,
            -0.5780476624345251,
            -0.5771647064287266,
            -0.5756824508385449,
            0.572627081266154,
            -0.569575104580563,
            -0.5682970955285169,
            0.5677817657322335,
            -0.5670682689629838,
            -0.5632680220187198,
            -0.5602247392998687,
            -0.558970237090569,
            -0.5565416160502439,
            0.5559944503659966,
            -0.5521459487757308,
            0.5518150287219244,
            -0.5504463501217829,
            -0.5494179907737972,
            -0.5492549765552738,
            0.5477645240877047,
            -0.5454964241429004,
            -0.5380761644629228,
            -0.5256721288091412,
            -0.5230513522011586,
            -0.5210771422932623,
            -0.5190782909415603,
            0.5174175670330773,
            -0.5169718631167534,
            -0.5143117097368979,
            -0.5139918553279218,
            -0.5053003768578158,
            0.504184711692842,
            -0.5014075595900223,
            -0.49972504011183916,
            -0.4996946059385279,
            0.49756210541955215,
            -0.4937378245121437,
            0.49129385035362444,
            0.49121249974578296,
            -0.49092486870740754,
            -0.4891374443520354,
            -0.4875173797810692,
            -0.4856925684729011,
            -0.4843650081195198,
            -0.4837834772031871,
            0.48312845837584156,
            0.4755729123463353,
            -0.46961924342562456,
            -0.4688457121637771,
            -0.4640932994769956,
            -0.4611738837471172,
            -0.4600122336661505,
            0.45888964406109656,
            0.4588068239871516,
            0.45820095369476355,
            -0.45730444757421035,
            0.45681134157483494,
            0.45555614786690035,
            0.45472506119110845,
            0.4532652756899375,
            0.4515624129242692,
            -0.4430155388738287,
            -0.44244208658740786,
            0.43660274096812013,
            -0.4350017924095689,
            0.4322371028819302,
            -0.429296719264725,
            -0.4278865378211524,
            0.42747915734152897,
            -0.42509331348707485,
            -0.42439913850210975,
            -0.42433984323369334,
            0.42303258968253926,
            -0.42291726595078993,
            0.41966790569229084,
            0.4164692757251208,
            0.4162659626998746,
            0.41586856564929653,
            0.41466190189450647,
            0.4121972626892493,
            -0.4114200207876198,
            -0.40752539436823887,
            -0.4068879058708913,
            -0.4068419758996157,
            0.4056667737407151,
            0.39626790999775885,
            -0.3959163446034679,
            0.3948053784173228,
            0.39228799456196245,
            -0.38720396904662435,
            -0.38653653107764047,
            0.38625537029934787,
            0.38458426506807064,
            0.3790735653141906,
            -0.37845926507293665,
            0.376935125502351,
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