{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "B3GAT1",
            "BCL2L11",
            "C1R",
            "BTK",
            "C4BPA",
            "C1QB",
            "BCAP31",
            "APP",
            "CXCR3",
            "CD40LG",
            "DEFB4A",
            "IRAK2",
            "CCL8",
            "EBI3",
            "HLA-DQA1",
            "CD59",
            "C3",
            "LILRB5",
            "MAPK14",
            "CCL15",
            "IL1R1",
            "TP53",
            "ADGRE2",
            "EGR2",
            "TLR3",
            "HFE",
            "BATF",
            "FADD",
            "CD9",
            "BCL2",
            "FKBP5",
            "LTB4R",
            "HRAS",
            "DEFB103A",
            "CXCR2",
            "CIITA",
            "PTGS2",
            "CR2",
            "BST2",
            "CCL3",
            "CD53",
            "CD86",
            "FYN",
            "CTNNB1",
            "IL4R",
            "CARD9",
            "PSMB5",
            "CCL20",
            "PTAFR",
            "DEFB103B",
            "SLC2A1",
            "S1PR1",
            "IL7",
            "CCND3",
            "IKZF1",
            "BCL3",
            "CCR8",
            "CRADD",
            "POLR1G",
            "KLRC3",
            "FCAR",
            "NFATC2",
            "ATG16L1",
            "CD160",
            "CD14",
            "CCL5",
            "IGF2R",
            "IRF7",
            "MAPKAPK2",
            "IL6",
            "MBP",
            "CFI",
            "CD80",
            "NT5E",
            "IRGM",
            "FN1",
            "CXCL11",
            "TNFSF11",
            "ATG12",
            "ABL1",
            "FAS",
            "LCP2",
            "CCL13",
            "LTB4R2",
            "CD79B",
            "CD46",
            "MALT1",
            "IL17A",
            "AIRE",
            "CCL2",
            "KLRA1P",
            "NOTCH2",
            "CCL22",
            "FCER1A",
            "FOXP3",
            "CFH",
            "DEFB1",
            "ITGA5",
            "SPP1",
            "HLA-DRB3",
            "CD19",
            "RAG2",
            "CCRL2",
            "CD36",
            "NOD2",
            "IL13RA1",
            "IL1RAP",
            "ACKR4",
            "SELPLG",
            "IL22",
            "SELE",
            "MUC1",
            "CFD",
            "PSMC2",
            "PDCD1",
            "LIF",
            "CCL19",
            "IL21R",
            "IL32",
            "ZBTB16",
            "BCL10",
            "BTLA",
            "CFB",
            "MAP4K4",
            "FCGR2B",
            "CD274",
            "GZMK",
            "EGR1",
            "IL16",
            "NLRP3",
            "ATG10",
            "EDNRB",
            "CD1D",
            "IL10",
            "IL1B",
            "MX1",
            "BLNK",
            "SLAMF6",
            "STAT4",
            "CD7",
            "IL4",
            "IL7R",
            "CD4",
            "MSR1",
            "POU2F2",
            "AICDA",
            "IL21",
            "CCR6",
            "TLR4",
            "CLEC5A",
            "IFI16",
            "IRF5",
            "BAX",
            "PDCD2",
            "CUL9",
            "TOLLIP",
            "GP1BB",
            "CLU",
            "TCF7",
            "CX3CR1",
            "PDCD1LG2",
            "IL1RN",
            "KCNJ2",
            "ITGA2B",
            "SLAMF1",
            "TNFSF8",
            "MAPK11",
            "ITLN2",
            "IL26",
            "CSF2",
            "CXCL8",
            "TNFSF15",
            "TNFRSF17",
            "TNFSF13B",
            "B2M",
            "IRF3",
            "KLRG1",
            "IL2RA",
            "HLA-C",
            "CXCL1",
            "ITGA4",
            "CCR10",
            "MME",
            "IFI35",
            "IL3",
            "CD48",
            "CD70",
            "CCL4",
            "ITGB1",
            "PAX5",
            "TIRAP",
            "TGFBI",
            "RAG1",
            "CD1A",
            "TAPBP",
            "CD163",
            "ARHGDIB",
            "CLEC6A",
            "IRAK1",
            "CASP8",
            "C5",
            "CCL16",
            "TAGAP",
            "IFNA2",
            "PTPN2",
            "HLA-DMB",
            "TCF4",
            "TLR1",
            "ADA",
            "ABCB1",
            "TRAF1",
            "PRKCD",
            "IRAK4",
            "MIF",
            "CTSC",
            "CCR2",
            "LCK",
            "CASP10",
            "C1QA",
            "NCAM1",
            "HAVCR2",
            "ATG7",
            "IRF4",
            "IFNL1",
            "CDKN1A",
            "MS4A1",
            "CD58",
            "IL6R",
            "UBE2L3",
            "CCL26",
            "PLA2G2E",
            "ENTPD1",
            "TRAF4",
            "IL15",
            "CD164",
            "IL12B",
            "PSMB7",
            "IL10RA",
            "CEACAM6",
            "CXCR6",
            "CLEC4E",
            "MYD88",
            "TNFRSF10C",
            "CCR1",
            "KLRG2",
            "ITGB2",
            "CD8B",
            "IFNAR1",
            "CCL23",
            "BST1",
            "CXCL12",
            "TLR2",
            "CD96",
            "STAT1",
            "TNFSF12",
            "ICAM1",
            "NFATC1",
            "STAT3",
            "SMAD5",
            "CD99",
            "CSF2RB",
            "IFNB1",
            "CD28",
            "ICAM3",
            "CSF1",
            "IL2RG",
            "STAT5A",
            "MRC1",
            "ITGAL",
            "IKBKE",
            "TGFBR1",
            "TLR9",
            "IL2RB",
            "PDGFB",
            "HLA-DPA1",
            "CD8A",
            "CD2",
            "RELB",
            "SYK",
            "IL27",
            "XCL1",
            "IFIH1",
            "CD276",
            "CD3D",
            "PRDM1",
            "PML",
            "CCL11",
            "TNFRSF9",
            "PTGER4",
            "C1S",
            "LILRB2",
            "PDGFRB",
            "S100A8",
            "IL6ST",
            "TLR5",
            "ARG2",
            "CD81",
            "HAMP",
            "PSMD7",
            "CD55",
            "KIR3DL1",
            "PLAU",
            "KLRB1",
            "FCGRT",
            "CD34",
            "CD74",
            "NOTCH1",
            "ITGAM",
            "CXCL2",
            "HLA-DOB",
            "TNFRSF1B",
            "PLAUR",
            "CEBPB",
            "THY1",
            "CMKLR1",
            "TNFRSF11A",
            "VCAM1",
            "CCR5",
            "IL20",
            "IL18",
            "CCL7",
            "C6",
            "TLR8",
            "LAIR1",
            "GPI",
            "CD40",
            "KLRC1",
            "LAG3",
            "PRF1",
            "IKBKB",
            "C7",
            "CR1",
            "LITAF",
            "TGFBR2",
            "NFKBIZ",
            "KIT",
            "JAK3",
            "HLA-DPB1",
            "IL11RA",
            "RTRAF",
            "CX3CL1",
            "SOCS3",
            "LILRA6",
            "NCF4",
            "IL5",
            "GATA3",
            "LILRA1",
            "IL17F",
            "MR1",
            "FCGR2A",
            "TRAF6",
            "SERPING1",
            "TNFSF4",
            "IRAK3",
            "ATM",
            "BID",
            "IFNL2",
            "IL1RL2",
            "CD83",
            "NOD1",
            "ICOS",
            "C1QBP",
            "KLRF1",
            "CD6",
            "TBK1",
            "TYK2",
            "CD247",
            "XCR1",
            "GBP1",
            "BCL6",
            "IFIT2",
            "HLA-A",
            "CXCL13",
            "ICAM5",
            "CEACAM8",
            "ELP1",
            "KIR3DL3",
            "C9",
            "NFKB2",
            "CSF3R",
            "IL23R",
            "AHR",
            "CD27",
            "CASP2",
            "CDH5",
            "TFRC",
            "GBP5",
            "CYBB",
            "HLA-B",
            "NOS2",
            "STAT6",
            "LTA",
            "SOCS1",
            "MAPK1",
            "ITGAE",
            "CD244",
            "ITGA6",
            "LY96",
            "PSMB9",
            "IFNGR1",
            "CCL18",
            "CD24",
            "RUNX1",
            "TNFRSF8",
            "LAMP3",
            "ICOSLG",
            "IL12A",
            "GNLY",
            "TNFSF10",
            "RORC",
            "IKZF3",
            "PPARG",
            "CLEC7A",
            "LILRB1",
            "TNFRSF13B",
            "CHUK",
            "TRAF3",
            "IL9",
            "CFP",
            "ILF3",
            "IRF1",
            "HLA-DRB1",
            "CASP3",
            "IDO1",
            "CTSG",
            "TNFRSF14",
            "RAF1",
            "PTPN6",
            "TIGIT",
            "NCR1",
            "DPP4",
            "PTK2",
            "IL18RAP",
            "TAP2",
            "IRF8",
            "LILRA3",
            "CD82",
            "LTBR",
            "ICAM4",
            "PLAAT4",
            "TNF",
            "PTPN22",
            "STAT5B",
            "PIGR",
            "HLA-DQB1",
            "LGALS3",
            "IL13",
            "GZMB",
            "HLA-DMA",
            "ITGAX",
            "JAK1",
            "CD5",
            "GZMA",
            "IKZF2",
            "LTF",
            "IL18R1",
            "KLRC4",
            "MASP2",
            "LEF1",
            "KLRC2",
            "XBP1",
            "SLAMF7",
            "MASP1",
            "CD79A",
            "TAL1",
            "HLA-DRA",
            "CD44",
            "CASP1",
            "SH2D1A",
            "CXCR4",
            "CSF1R",
            "TICAM1",
            "LILRA5",
            "LILRB3",
            "MBL2",
            "PPBP",
            "ICAM2",
            "LILRA2",
            "NFATC3",
            "CCR7",
            "CXCR1",
            "LILRB4",
            "TRAF2",
            "VTN",
            "EOMES",
            "ARG1",
            "TAP1",
            "CXCL10",
            "IL17B",
            "CTSS",
            "LILRA4",
            "CEACAM1",
            "IL1A",
            "MAP4K2",
            "IL1R2",
            "IL19",
            "SMAD3",
            "IFITM1",
            "IL1RL1",
            "GFI1",
            "ZEB1",
            "CLEC4A",
            "C2",
            "KIR3DL2",
            "CISH",
            "C8B",
            "IFNG",
            "KLRD1",
            "DUSP4",
            "CXCL9",
            "C8A",
            "MCL1",
            "FCER1G",
            "TNFAIP6",
            "CD22",
            "PLA2G2A",
            "PYCARD",
            "S100A9",
            "TLR7",
            "CCL24",
            "MAF",
            "SRC",
            "CAMP",
            "TNFRSF4",
            "IKBKG",
            "SELL",
            "TNFAIP3",
            "IL2",
            "ITLN1",
            "JAK2",
            "NFIL3",
            "CD3E",
            "RELA",
            "KLRK1",
            "IL23A",
            "STAT2",
            "TGFB1",
            "PSMB10",
            "IL22RA2",
            "CD209",
            "TNFRSF13C",
            "ZAP70",
            "MARCO",
            "SIGIRR",
            "TRAF5",
            "IL12RB1",
            "TBX21",
            "ETS1",
            "KLRF2",
            "MAP4K1",
            "PECAM1",
            "SKI",
            "STING1",
            "IFNAR2",
            "PSMB8",
            "NFKB1",
            "GPR183",
            "NFKBIA",
            "C8G"
        ],
        "Coefficient": [
            0.11697126575200906,
            -0.08833576539820454,
            0.0777831049487349,
            0.07770235587104173,
            0.0744446110797551,
            -0.07302513353796163,
            -0.07253960201235589,
            0.070335942772477,
            0.07021076246421197,
            0.06867139971599666,
            0.06739564778981129,
            0.06664608274154883,
            -0.06556548149827808,
            -0.06526285355158984,
            -0.06478702004997983,
            0.06278482342752133,
            0.06212882064396317,
            -0.05904115652547952,
            0.05869151146973863,
            -0.057872596176415096,
            -0.057465349371751295,
            0.05661549193387189,
            0.056571182766462016,
            -0.056522207648835754,
            -0.056158820823426096,
            -0.056145228023839054,
            0.05583387440303021,
            -0.05526495440660539,
            0.05519632426898176,
            -0.054658690391481246,
            -0.054544993046823864,
            0.054254417703296635,
            -0.05351994972847362,
            0.0521519328138513,
            0.05180470837798427,
            0.05167572482881654,
            0.051592429252797535,
            0.05094756871454689,
            0.05061746206168232,
            0.05054001654913172,
            0.04932292704528234,
            -0.04865747201117771,
            0.0481456309404309,
            -0.047851783330457136,
            0.04712985229282497,
            -0.04702881371158347,
            0.04636624777752747,
            -0.04616090836080898,
            0.046072342628481505,
            -0.046014659123412495,
            0.045788289114456704,
            0.04548704539022973,
            0.04514466249836485,
            -0.044476319491813514,
            -0.04430126222478103,
            0.0440846656138217,
            -0.043860213273042264,
            -0.043686740731689745,
            0.04328520401144061,
            -0.04299307508122573,
            0.04289799210825479,
            0.0424422706528732,
            -0.04191755861625974,
            -0.04189095751814506,
            -0.041427210201263685,
            0.040767209008337454,
            0.04052981654030411,
            0.040497946735381055,
            -0.040458719916857545,
            0.03984154880069582,
            0.03965385564088478,
            0.03943582134878342,
            -0.03863832558896173,
            0.03806180087896304,
            -0.038025757448020496,
            0.03798929313952089,
            0.03786613409211933,
            0.03754340517257253,
            -0.037362246666507684,
            -0.036942407408136556,
            0.03682673814875259,
            -0.03675538970801949,
            0.03666567023188936,
            -0.03653531757333785,
            -0.03647042808772908,
            0.03641122285508218,
            -0.03635582952019415,
            -0.03628018189633749,
            -0.03574782389399862,
            -0.03570794276932576,
            -0.035662590062788796,
            0.03526646912281157,
            0.03522672754428453,
            0.034952137638665885,
            0.034857802706612165,
            -0.03443550633844832,
            -0.034429113647950774,
            0.03421536469699002,
            -0.03420481980218094,
            0.0341232621630854,
            0.033952094175411264,
            -0.033916815473512364,
            0.033824012230888316,
            -0.03368314101193453,
            0.033472965199452254,
            -0.03336037811964334,
            -0.03311823521658021,
            0.032871903259757355,
            -0.03260750504868388,
            0.03232065570432016,
            0.03231414586000461,
            0.032282723387510544,
            -0.03213469396210107,
            -0.03181992050620957,
            0.0316602784652461,
            -0.03145894331491984,
            0.03141731950389393,
            0.031076554531560205,
            0.030989465737572826,
            0.030396646925760693,
            0.03010979264180408,
            -0.029942377026273972,
            -0.02981549392411431,
            -0.029788244958962398,
            -0.02952819937312669,
            0.02943496578119734,
            -0.029379088587719954,
            -0.02928504626570439,
            -0.02925514063362403,
            0.02924452665410589,
            0.029229827151021338,
            -0.029210606461432562,
            0.0291134480716185,
            0.028866804282408967,
            0.028603483750005203,
            -0.02847107570338095,
            -0.02844642167796687,
            0.028439864288973847,
            0.02821767334538777,
            0.028216814306008347,
            -0.027983080511571872,
            -0.027897309556242547,
            0.027810513687711064,
            -0.02745390450215677,
            -0.027072268585136863,
            -0.02704302201331591,
            -0.026959806507931797,
            -0.026737374985747527,
            -0.02673108734459614,
            -0.02661042835287813,
            -0.026556255873612013,
            -0.026545789330031908,
            0.026534956790669407,
            -0.02649407317335969,
            0.026472658586343623,
            -0.026372839203425494,
            0.026325470154611893,
            0.026236818943072476,
            -0.026129111507187337,
            -0.02599517384247593,
            0.02598138709407938,
            -0.025716317376247348,
            0.025679117019475322,
            0.025567670340469167,
            -0.0255598427952231,
            0.025490072919707674,
            0.02538292361017513,
            0.025346777356005868,
            0.025250017901815195,
            -0.025237991505557104,
            -0.024936161495826028,
            0.02491981080721805,
            0.024892263608701365,
            0.02468329901809906,
            0.024595100910411227,
            -0.024504643118157435,
            -0.02446467671305025,
            0.024450643547042874,
            -0.02436968610538096,
            -0.024356698288006278,
            -0.02429423742670461,
            0.0242895995591287,
            -0.024084698973231452,
            -0.024068463516851987,
            -0.024011302160044,
            0.023816535922372876,
            -0.023768911234850157,
            -0.02364580967982235,
            0.02357465390489486,
            -0.02355834777875871,
            0.023527401088143208,
            -0.023441898979644122,
            -0.023430481697452363,
            0.023124858983153963,
            0.023099531417421278,
            -0.023020188243763423,
            0.022987615408931468,
            0.022963595315195585,
            0.022880966425881156,
            -0.02259416676318767,
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            0.02246599864691708,
            -0.022462322010485074,
            -0.022389271656747544,
            -0.02237370138863607,
            -0.022300757125641973,
            0.022211282341589537,
            0.0221433205471877,
            -0.022135827062093633,
            -0.021988950894246965,
            0.021764484281759828,
            -0.02173241495805207,
            -0.02167385550219388,
            -0.021594219932859295,
            -0.02133654157159558,
            0.02133202589478101,
            0.02126008074705742,
            -0.021161078747574193,
            0.021035498638843086,
            -0.020948146975661268,
            -0.02093709514514138,
            -0.02086750272232992,
            -0.02066639061687707,
            0.020640071855178698,
            0.020624274222729607,
            0.0202056374030783,
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            -0.020122895805875445,
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            0.02003554804710424,
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            0.01992497623570095,
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            -0.01969928109816608,
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            0.019496046306822317,
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            -0.01934202288136807,
            0.01932898906303312,
            0.019295250442942672,
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            -0.018982840805790137,
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            0.018605499455501596,
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            0.018488573632664207,
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            0.018228923320682544,
            0.018206099864431655,
            -0.01812087004845667,
            -0.01811143201231261,
            0.017790080556621353,
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