{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "C1R",
            "B3GAT1",
            "C4BPA",
            "BCAP31",
            "BTK",
            "C1QB",
            "CD40LG",
            "DEFB4A",
            "APP",
            "CCL8",
            "CXCR3",
            "HLA-DQA1",
            "IRAK2",
            "EBI3",
            "LILRB5",
            "CCL15",
            "C3",
            "MAPK14",
            "CD59",
            "BCL2",
            "TP53",
            "IL1R1",
            "EGR2",
            "HFE",
            "TLR3",
            "BATF",
            "FADD",
            "HRAS",
            "LTB4R",
            "CD9",
            "CCL3",
            "PTGS2",
            "FKBP5",
            "CD86",
            "CIITA",
            "BST2",
            "CR2",
            "CXCR2",
            "DEFB103A",
            "ADGRE2",
            "CD53",
            "ATG16L1",
            "CTNNB1",
            "DEFB103B",
            "CCL20",
            "PTAFR",
            "PSMB5",
            "CCND3",
            "CARD9",
            "BCL3",
            "FYN",
            "IL7",
            "IL4R",
            "NFATC2",
            "S1PR1",
            "CCL5",
            "SLC2A1",
            "IKZF1",
            "POLR1G",
            "MBP",
            "FCAR",
            "KLRC3",
            "CRADD",
            "CCR8",
            "IGF2R",
            "FN1",
            "IL6",
            "CD160",
            "CCL22",
            "IRF7",
            "NT5E",
            "ACKR4",
            "CCL13",
            "IL17A",
            "CCRL2",
            "MAPKAPK2",
            "IRGM",
            "CFI",
            "FOXP3",
            "ATG12",
            "LCP2",
            "CD80",
            "LTB4R2",
            "MALT1",
            "CD14",
            "TNFSF11",
            "CFH",
            "AIRE",
            "CD46",
            "NOTCH2",
            "FAS",
            "CCL2",
            "HLA-DRB3",
            "ABL1",
            "SPP1",
            "CD36",
            "ITGA5",
            "CD79B",
            "CXCL11",
            "ATG7",
            "IL22",
            "MUC1",
            "CFD",
            "DEFB1",
            "RAG2",
            "CD19",
            "NOD2",
            "SELE",
            "IL1RAP",
            "FCER1A",
            "ATG10",
            "MAP4K4",
            "KLRA1P",
            "PSMC2",
            "SELPLG",
            "LIF",
            "ZBTB16",
            "PDCD1",
            "NLRP3",
            "FCGR2B",
            "MX1",
            "IL13RA1",
            "GZMK",
            "IL32",
            "EDNRB",
            "IL16",
            "EGR1",
            "CCL19",
            "IL10",
            "BTLA",
            "CD7",
            "BLNK",
            "IL1B",
            "MSR1",
            "TNFSF15",
            "IL4",
            "CD274",
            "IL21",
            "IL21R",
            "GP1BB",
            "KCNJ2",
            "SLAMF6",
            "POU2F2",
            "STAT4",
            "BCL10",
            "BAX",
            "TOLLIP",
            "CLEC5A",
            "CUL9",
            "IL26",
            "TCF7",
            "TLR4",
            "PDCD2",
            "IL7R",
            "IFI16",
            "TNFSF8",
            "PDCD1LG2",
            "B2M",
            "ITGA4",
            "ITGA2B",
            "CD70",
            "KLRG1",
            "CD4",
            "CSF2",
            "CCL16",
            "CD48",
            "IRF5",
            "IL2RA",
            "CLEC6A",
            "TNFSF13B",
            "ITLN2",
            "TIRAP",
            "IL1RN",
            "IFI35",
            "ITGB1",
            "CD1D",
            "CD1A",
            "TGFBI",
            "SLAMF1",
            "MME",
            "CFB",
            "IRF3",
            "CCR1",
            "TNFRSF17",
            "CLU",
            "RAG1",
            "CXCL8",
            "HLA-DMB",
            "MAPK11",
            "AICDA",
            "IRF4",
            "TAPBP",
            "PRKCD",
            "IL3",
            "MS4A1",
            "CCR6",
            "IRAK1",
            "IFNA2",
            "PAX5",
            "CCL4",
            "CCL26",
            "CASP8",
            "CXCL1",
            "CX3CR1",
            "CD8B",
            "HAVCR2",
            "TNFRSF10C",
            "TRAF1",
            "ARHGDIB",
            "HLA-C",
            "CD163",
            "IL12B",
            "PSMB7",
            "IKBKE",
            "TCF4",
            "CTSC",
            "PTPN2",
            "IL6R",
            "IRAK4",
            "ENTPD1",
            "NCAM1",
            "UBE2L3",
            "TAGAP",
            "LCK",
            "TLR1",
            "CD28",
            "ABCB1",
            "IFNL1",
            "MYD88",
            "CXCR6",
            "C5",
            "IL27",
            "CDKN1A",
            "CCL23",
            "MIF",
            "ITGAL",
            "CD96",
            "IL10RA",
            "KLRG2",
            "BST1",
            "TRAF4",
            "CASP10",
            "PDGFB",
            "CCR2",
            "ITGB2",
            "CLEC4E",
            "CD164",
            "TNFSF12",
            "CD58",
            "TLR9",
            "C1QA",
            "IL2RG",
            "ICAM1",
            "PLA2G2E",
            "STAT1",
            "CSF1",
            "STAT3",
            "IL15",
            "CEACAM6",
            "NFATC1",
            "CD8A",
            "PML",
            "CCR10",
            "C6",
            "RELB",
            "IFNB1",
            "STAT5A",
            "ICAM3",
            "HLA-DPA1",
            "TLR2",
            "CD276",
            "XCL1",
            "CCL11",
            "SYK",
            "KLRB1",
            "CD99",
            "CR1",
            "IL6ST",
            "CSF2RB",
            "SMAD5",
            "ARG2",
            "CD40",
            "TNFRSF9",
            "IFIH1",
            "PRDM1",
            "KLRC1",
            "CD81",
            "TGFBR1",
            "PTGER4",
            "LILRB2",
            "GATA3",
            "CD34",
            "NOTCH1",
            "PLAU",
            "CD74",
            "CXCL12",
            "S100A8",
            "PSMD7",
            "CD55",
            "MRC1",
            "ADA",
            "IL11RA",
            "ITGAM",
            "IL2RB",
            "TLR8",
            "CX3CL1",
            "PDGFRB",
            "TLR5",
            "CXCL2",
            "KIT",
            "IL17F",
            "NFKBIZ",
            "KIR3DL1",
            "FCGRT",
            "IL20",
            "PRF1",
            "CD2",
            "PLAUR",
            "C7",
            "GPI",
            "IL1RL2",
            "LAG3",
            "TNFRSF1B",
            "XCR1",
            "CD3D",
            "CEBPB",
            "HAMP",
            "LITAF",
            "NCF4",
            "THY1",
            "IFNAR1",
            "KLRF1",
            "IL18",
            "IL5",
            "LILRA6",
            "VCAM1",
            "IRAK3",
            "TNFRSF11A",
            "LAIR1",
            "HLA-DOB",
            "NOD1",
            "IFNL2",
            "FCGR2A",
            "TRAF6",
            "HLA-DPB1",
            "MR1",
            "LTA",
            "SERPING1",
            "JAK3",
            "IKBKB",
            "RTRAF",
            "TNFSF4",
            "TBK1",
            "NFKB2",
            "SOCS3",
            "LILRA1",
            "GBP5",
            "TGFBR2",
            "CCR5",
            "BID",
            "ELP1",
            "IL23R",
            "GBP1",
            "NOS2",
            "HLA-A",
            "MAF",
            "CD6",
            "STAT6",
            "C1QBP",
            "CCL18",
            "CEACAM8",
            "CASP2",
            "CD24",
            "KIR3DL3",
            "TFRC",
            "CXCL13",
            "IL12A",
            "ICOS",
            "CCL7",
            "C1S",
            "BCL6",
            "TYK2",
            "LY96",
            "HLA-DMA",
            "CASP3",
            "ITGA6",
            "ITGAE",
            "CD82",
            "SOCS1",
            "LAMP3",
            "ICOSLG",
            "ICAM5",
            "CMKLR1",
            "IFNGR1",
            "CD83",
            "LILRB1",
            "TNFRSF13B",
            "PTPN6",
            "TNFRSF8",
            "MAPK1",
            "HLA-B",
            "CYBB",
            "CD247",
            "PSMB9",
            "TNFRSF14",
            "CLEC7A",
            "IL9",
            "CSF3R",
            "CD79A",
            "CD5",
            "ILF3",
            "HLA-DRB1",
            "GZMB",
            "GNLY",
            "PPARG",
            "CD244",
            "TNF",
            "C9",
            "AHR",
            "LTF",
            "PLAAT4",
            "IFIT2",
            "IL18RAP",
            "MASP1",
            "CISH",
            "IRF1",
            "IKZF3",
            "ARG1",
            "DUSP4",
            "CD27",
            "TAP2",
            "ATM",
            "CDH5",
            "RUNX1",
            "TIGIT",
            "IRF8",
            "PTPN22",
            "CD44",
            "LEF1",
            "JAK1",
            "PIGR",
            "C8A",
            "LGALS3",
            "HLA-DQB1",
            "CHUK",
            "RORC",
            "IKZF2",
            "XBP1",
            "IDO1",
            "LILRA3",
            "NCR1",
            "IL13",
            "TRAF2",
            "ITGAX",
            "LTBR",
            "TRAF3",
            "PTK2",
            "MASP2",
            "IL18R1",
            "LILRB3",
            "STAT5B",
            "CFP",
            "TNFSF10",
            "IFNAR2",
            "RAF1",
            "CXCR4",
            "CEACAM1",
            "SLAMF7",
            "KLRC4",
            "LILRA5",
            "TAL1",
            "EOMES",
            "HLA-DRA",
            "CLEC4A",
            "ZEB1",
            "CASP1",
            "IL1R2",
            "CXCR1",
            "GFI1",
            "CTSG",
            "ICAM4",
            "SH2D1A",
            "IL19",
            "MBL2",
            "KLRC2",
            "ICAM2",
            "IL17B",
            "LILRA4",
            "VTN",
            "C2",
            "LILRB4",
            "CSF1R",
            "KIR3DL2",
            "LILRA2",
            "CTSS",
            "SRC",
            "PPBP",
            "GZMA",
            "DPP4",
            "NFIL3",
            "TNFAIP6",
            "IL12RB1",
            "IFNG",
            "IL1A",
            "KLRD1",
            "TICAM1",
            "TAP1",
            "NFATC3",
            "C8G",
            "IL22RA2",
            "IL1RL1",
            "CXCL9",
            "CXCL10",
            "IL2",
            "RELA",
            "FCER1G",
            "MAP4K1",
            "KLRK1",
            "PSMB10",
            "MARCO",
            "C8B",
            "PLA2G2A",
            "TGFB1",
            "SIGIRR",
            "JAK2",
            "S100A9",
            "SMAD3",
            "SELL",
            "CD22",
            "TNFAIP3",
            "CD209",
            "SKI",
            "IKBKG",
            "ETS1",
            "STAT2",
            "MCL1",
            "KLRF2",
            "GPR183",
            "TBX21",
            "CCR7",
            "CAMP",
            "PYCARD",
            "NFKBIA",
            "TNFRSF4",
            "PSMB8",
            "CCL24",
            "TLR7",
            "ZAP70",
            "IL23A",
            "NFKB1",
            "ITLN1",
            "STING1",
            "PECAM1",
            "TRAF5",
            "TNFRSF13C",
            "CD3E",
            "MAP4K2",
            "IFITM1"
        ],
        "Coefficient": [
            0.11620922679262398,
            -0.08932170440613915,
            0.08024120045921455,
            0.07787768537956959,
            0.0774526269552317,
            -0.07307219757858126,
            0.07302094968682848,
            -0.07233718452155086,
            0.0704873378521018,
            0.06952977336410934,
            -0.06698912140426252,
            0.06566787339262875,
            -0.06473818101588981,
            0.06455897269114495,
            0.06427105101353285,
            -0.06281195899718393,
            0.06034440398355023,
            -0.06017241653975177,
            0.06006731136377383,
            0.05921820651927776,
            -0.058849783204697144,
            -0.058248424810949086,
            0.05808555778073832,
            -0.05759653246235997,
            0.05757560485082481,
            -0.05604123123408129,
            -0.05588389110367518,
            0.05551120987575,
            0.05476976923990061,
            -0.05406916397580336,
            0.0532395274213745,
            0.05281337676436244,
            -0.052740023781826254,
            -0.052512657894334,
            0.05171446326244065,
            -0.05152712773354393,
            -0.05120150474970775,
            0.051152691865202785,
            0.05048192296178253,
            0.050371958619818094,
            0.0501804235083861,
            0.04882692499758139,
            -0.0488019324257793,
            0.047640695159629494,
            -0.047426076423117074,
            -0.04724220850227109,
            0.046778072581599994,
            -0.04661016253092397,
            0.04657379380987195,
            0.0463825494756394,
            0.04604620940830486,
            -0.046046109586785275,
            -0.04580211499932851,
            0.04560302456992263,
            -0.04547983794016956,
            0.044973414482047676,
            -0.04409087451203762,
            -0.04372934406660641,
            0.04359938208203701,
            0.04336246560055197,
            -0.04285408955657969,
            0.04273042561118918,
            -0.04241737092987666,
            -0.042210306457495246,
            0.04215161213820472,
            -0.041355154089536106,
            0.04077259876380582,
            -0.04053771026792546,
            0.04040128722461375,
            0.04022925364328469,
            0.04021523706950936,
            0.03932466096547457,
            0.03922502537569307,
            0.03898647552749264,
            0.038919453685928654,
            -0.03853230699874524,
            -0.0384614700598753,
            0.03843542840708856,
            0.03838846959024068,
            0.03797188658339179,
            0.03791793067662968,
            -0.03764645778406717,
            0.0373225783624928,
            -0.03723226047532127,
            -0.03714389505060785,
            0.03703524208006328,
            -0.03683007163968647,
            0.0366774881109683,
            -0.036643495714270065,
            0.03646174653634501,
            -0.036305083244196325,
            -0.03545835306445789,
            0.03526842242347324,
            0.03514612959762717,
            0.035130968235433026,
            -0.03506318813278041,
            -0.03492217669170182,
            0.03469900817408008,
            -0.0340694843771131,
            0.0340165132760171,
            -0.033897797641892546,
            -0.03373211904665175,
            0.03370449070854484,
            0.03347322664776748,
            -0.03343376591592159,
            0.033399568576572905,
            -0.033332016364717346,
            -0.03298599887346345,
            0.032697798758117756,
            -0.032677502204040206,
            -0.03262910568143455,
            -0.03259126338702732,
            -0.032432719947233984,
            0.03239746417722945,
            0.03229236028824398,
            0.032271840067414556,
            -0.03213035990485826,
            0.03206467645023684,
            0.03177391110913888,
            -0.031662713990619124,
            0.031510359455230834,
            -0.03141532661868374,
            -0.0311245244814557,
            0.03110262637179459,
            0.030401474049569673,
            -0.030213371199256774,
            0.02995975231553209,
            0.029637064566344736,
            0.029633467730136077,
            0.029592598083966495,
            0.02955133975406858,
            -0.029355912296233598,
            -0.029066534298537172,
            -0.028938962733346302,
            0.028918911846661132,
            -0.02890696007917237,
            -0.02875095318938266,
            0.028446163454645092,
            0.028175236664537782,
            -0.028072140835339487,
            -0.028005542113971174,
            0.027897134291483904,
            -0.02788848394094907,
            -0.027678292577270273,
            0.02754516360743318,
            -0.02751903862634766,
            -0.027204680939726656,
            -0.02720136408430244,
            0.026982437793800967,
            0.026892295065021204,
            -0.026883193754049385,
            0.02687551441692789,
            -0.026750931009163217,
            0.026610523346646184,
            -0.02645615501100428,
            -0.02645291659387272,
            -0.026410114648742,
            0.026402644079807188,
            0.02608669120998033,
            0.02606258777839878,
            -0.026007635169918067,
            -0.02599007659480304,
            0.02590301966124425,
            0.02577413539395555,
            -0.025708875051425963,
            -0.025636682962917816,
            0.025619864344124266,
            -0.025537417453461254,
            -0.025505169654297822,
            -0.025449796480918465,
            -0.02544421431471936,
            -0.025354790903415546,
            -0.025348956894364744,
            -0.025222690229427032,
            -0.02520506806063021,
            0.024888512389959812,
            0.02479843993528024,
            0.024796026944395182,
            0.02476893251234783,
            -0.02458014418136339,
            0.024559519262872972,
            0.024533587048865706,
            -0.024368807489658598,
            -0.02412879704755981,
            0.023943420677169376,
            0.02390527606581984,
            0.023823674711284534,
            -0.02380452583148045,
            0.023676445405542982,
            0.023579451543246397,
            0.023203112959886744,
            0.023115012750897317,
            -0.023050709761768165,
            0.02293104259043314,
            0.022854639612079973,
            -0.022585288837700893,
            -0.02257589693102127,
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            0.022385438723295716,
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            0.02209751040939513,
            0.022078604473590092,
            0.021943946297441536,
            -0.02174846708780246,
            0.02163396713954515,
            -0.021633418712513414,
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            -0.021434827048701924,
            0.021340635607936993,
            0.021334659636389555,
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            -0.02127096172701802,
            -0.02113329115055608,
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            0.021021937572690212,
            -0.020972726731779624,
            -0.020912914090341694,
            -0.020874236957808257,
            -0.02084833452174409,
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            0.0207997468171047,
            -0.02079492719354803,
            -0.02067133526140365,
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            0.02063986992072879,
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            -0.02031655631575405,
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            -0.01943767085690694,
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            -0.019228734071234262,
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            -0.019045268602097015,
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            0.018532728610799184,
            0.018458309040943914,
            0.018314572541367116,
            -0.01822988260293929,
            -0.018174895768364622,
            -0.0181645045289627,
            0.01809031143576659,
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