{
    "significant_genes": {
        "Variable": [
            "MRAP",
            "MYOC",
            "NPPC",
            "OR52M1",
            "PPP1R2B",
            "LOC100192426",
            "RGPD8",
            "TNK1",
            "MS4A12",
            "MGC15885",
            "SPDYE2",
            "KRT3",
            "PLA2G2C",
            "CIB3",
            "OR52K2",
            "TM4SF20",
            "GARIN5B",
            "KCNH2",
            "LIPJ",
            "FAM83C",
            "YIPF7",
            "GAGE12J",
            "FAM3B",
            "UCP1",
            "ULK4P2",
            "OR10A3",
            "NEU2",
            "FAM99B",
            "FCRLA",
            "TNNI1",
            "PCSK9",
            "SLC36A3",
            "INTS4P2",
            "DMP1",
            "SNORA3B",
            "HCRTR1",
            "WT1",
            "PPIAL4A",
            "CPLX4",
            "USP29",
            "PRAMEF18",
            "ZBED1",
            "TMC3",
            "SPIB",
            "TMPRSS11A",
            "MCCC1",
            "PFN4",
            "TMPRSS11BNL",
            "NXPH2",
            "HBZ",
            "CCDC198",
            "LY6S-AS1",
            "ALDH1A1",
            "PDCL2",
            "NHERF4",
            "TRIM14",
            "PLEKHG7",
            "UPK3BL1",
            "OR10S1",
            "CLEC12B",
            "FABP2",
            "TMEM244",
            "SPINK13",
            "ADGRF4",
            "PLEKHG4",
            "KRTAP10-4",
            "FREY1",
            "EVX2",
            "RGS16",
            "KLC3",
            "FRG2",
            "C12orf54",
            "PIGR",
            "KRTAP9-9",
            "OR4M2",
            "PROX2",
            "DYNAP",
            "HCN4",
            "PCDHGB2",
            "MRI1",
            "PAX8",
            "LOC730101",
            "ADH1A",
            "PXT1",
            "FSHR",
            "CSPG4P2Y",
            "HAMP",
            "ADGRF2P",
            "PEDS1-UBE2V1",
            "PMS2P5",
            "SNORD67",
            "PLPP1",
            "MROH6",
            "PCDHGB1",
            "L1TD1",
            "POU1F1",
            "PRM2",
            "PASD1",
            "LACRT",
            "GPR148",
            "LGALS9B",
            "IQCF6",
            "AFM",
            "FLG2",
            "LEP",
            "SLED1",
            "SDHAF3",
            "POLR2J2",
            "CCL1",
            "SPINK5",
            "APOF",
            "TFAP2A",
            "C16orf90",
            "SUPT20HL1",
            "C10orf53",
            "TDRD12",
            "OR6T1",
            "OR6K6",
            "FIBIN",
            "FAM136BP",
            "PRAMEF5",
            "CRISP3",
            "GOLGA8DP",
            "OR10Q1",
            "OR2T12",
            "CATSPER4",
            "BGLAP",
            "TRIM10",
            "ZNF311",
            "FKSG29",
            "ERRFI1",
            "HORMAD1",
            "SNORA28",
            "OR6B3",
            "TEX38",
            "ATP5MC3",
            "ARFGAP3",
            "CD300LD-AS1",
            "USH1G",
            "RHAG",
            "DUSP19",
            "MIA2",
            "MYH8",
            "MAGEC2",
            "PAGE3",
            "CHODL-AS1",
            "CASR",
            "EPS8L3",
            "HAO2",
            "LOC284009",
            "DNAJC15",
            "MOGAT3",
            "XG",
            "ROBO2",
            "UGT1A7",
            "KRT12",
            "OTOP1",
            "LIMS3-LOC440895",
            "NCR1",
            "RPTN",
            "PPAN-P2RY11",
            "FAM221A",
            "KRTAP4-7",
            "CIB4",
            "PCDHGA6",
            "PPEF2",
            "TPRX1",
            "PNLIPRP1",
            "PRSS3P2",
            "ASZ1",
            "LOC284788",
            "PCDHA8",
            "SLC22A20P",
            "LINC00469",
            "ANKRD2",
            "PKP1",
            "MUC15",
            "ADGRF1",
            "RSPH6A",
            "SMN2",
            "LINC00588",
            "TTTY19",
            "TPD52",
            "OR2T33",
            "TFPI2",
            "F2",
            "PKHD1",
            "STON1-GTF2A1L",
            "CXADRP3",
            "DDI1",
            "ACE2",
            "S100G",
            "BTLA",
            "SLC35G3",
            "SDR9C7",
            "FAM27E5",
            "MRPL42P5",
            "ZFP92",
            "OR2T35",
            "GSTA5",
            "ADGRF3",
            "DNLZ",
            "RPL21P44",
            "TAS2R1",
            "MS4A2",
            "DPRX",
            "OR14J1",
            "CLDN18",
            "IGFBP5",
            "CCDC196",
            "AS3MT",
            "SLC30A2",
            "SFTPA1",
            "KRTAP10-5",
            "DPPA2",
            "TTTY22",
            "SNAR-F",
            "DIO3OS",
            "S100A7",
            "ARRDC5",
            "SNORA36B",
            "LRRC69",
            "ALPG",
            "GP2",
            "FBXL21P",
            "GDPGP1",
            "LIN7A",
            "MINDY4",
            "ASB12",
            "FRMD1",
            "UGT1A9",
            "PSG5",
            "OR8A1",
            "IL37",
            "TRIM60",
            "FAM66D",
            "MIOX",
            "TBC1D26",
            "SPDYE6",
            "TNMD",
            "TPD52L3",
            "ANGPTL3",
            "PRG1",
            "TAS2R3",
            "OR13F1",
            "PPP1R14D",
            "WBP2NL",
            "CHRNG",
            "MAGEB18",
            "TAAR5",
            "PCDHB2",
            "TRPM3",
            "KASH5",
            "IGFL2",
            "OR10P1",
            "TBC1D3G",
            "GOLGA8EP",
            "H2AB1",
            "ASPRV1",
            "TRIM77",
            "PCDHB6",
            "OR5AP2",
            "AKR7A3",
            "KRTAP9-2",
            "TAS2R30",
            "FCRL3",
            "PCDHGA8",
            "MID2",
            "LRRC70",
            "SAYSD1",
            "DEFB109A",
            "CDH23",
            "CRYGB",
            "CEACAM7",
            "KLHL14",
            "LDLRAD1",
            "OR2B2",
            "CERS3",
            "RWDD2B",
            "CRYBB3",
            "H2BC1",
            "DNAJC25-GNG10",
            "LOC389705",
            "OR56A4",
            "OR52I2",
            "LOC728024",
            "PXMP4",
            "DEFB112",
            "IHO1",
            "GAGE12D",
            "PCAT4",
            "OR2G2",
            "FAM47C",
            "KCNK10",
            "TMEM185B",
            "OR9Q1",
            "VN1R4",
            "USP26",
            "SIGLEC6",
            "FBXO6",
            "AIRE",
            "RPA4",
            "AP1M2",
            "SPINK4",
            "RNF182",
            "OR2A12",
            "SMCO2",
            "CLP1",
            "C11orf16",
            "TAS2R9",
            "OR5AN1",
            "MIR3667HG",
            "SNX31",
            "ASIP",
            "TBXT",
            "CLEC4GP1",
            "ZFP1",
            "IFNA1",
            "SUN5",
            "FAM138B",
            "MUCL1",
            "OR4X2",
            "MLEC",
            "DSCR9",
            "CDRT15",
            "RGPD5",
            "DDX43",
            "RSPO4",
            "XAGE3",
            "DEFB104A",
            "S100A1",
            "NETO2",
            "CYP2F1",
            "HELT",
            "CTAG2",
            "PM20D1",
            "SPATA18",
            "OR11L1",
            "AMDHD1",
            "OR2A14",
            "OR4S1",
            "SPDYC",
            "GPHA2",
            "ZAN",
            "PLSCR4",
            "HBG2",
            "CD209",
            "TG",
            "ICAM4",
            "DCAF8",
            "MAGEB2",
            "PRAME",
            "CCDC152",
            "C1orf185",
            "CSH2",
            "GDE1",
            "TMPRSS11B",
            "KIF25",
            "ZNF735",
            "SUGT1",
            "KRTAP27-1",
            "SNORA38B",
            "INE2",
            "LILRA3",
            "NCR2",
            "CFAP144P1",
            "GLYCAM1",
            "MAGEB4",
            "OR1K1",
            "IDO2",
            "MGAM",
            "CPA6",
            "CD300LD",
            "LINC00207",
            "CPZ",
            "RNASE7",
            "GUCY2GP",
            "ZNF354A",
            "FRG2B",
            "ADRB1",
            "POR",
            "LILRB5",
            "LINC00200",
            "TBC1D3P2",
            "ACTBL2",
            "PAPSS1",
            "SLC26A5",
            "LPAR2",
            "SMN1",
            "LINC00473",
            "TBX10",
            "OR1S1",
            "OR4C13",
            "B3GNT9",
            "DEFB129",
            "IL21",
            "KPRP",
            "SLC46A1",
            "TBPL2",
            "SMCO3",
            "STAG3",
            "IQCF5",
            "SNORA79",
            "SLC35E2B",
            "TREH",
            "TUBB7P",
            "GTF2IRD2",
            "SGCZ",
            "SNORA69",
            "SERHL",
            "PCDHA9",
            "KLK1",
            "OR2M5",
            "OR51G2",
            "HRNR",
            "TTTY13",
            "ZNF99",
            "SNORA61",
            "WFDC10B",
            "IZUMO1R",
            "LRRC19",
            "NPHP3-AS1",
            "SERPINC1",
            "OR6C76",
            "SOX14",
            "ANXA8L1",
            "H3C13",
            "SPACA3",
            "NIPAL1",
            "OR2AT4",
            "OR51Q1",
            "MUC21",
            "DEFB131A",
            "B4GALNT2",
            "EGFEM1P",
            "OR4D6",
            "NME6",
            "DYTN",
            "DEFB136",
            "RHBG",
            "OR4C45",
            "CA6",
            "BPIFA4P",
            "SLC25A2",
            "PAGE1",
            "ELOA2",
            "FGL1",
            "CRH",
            "SPANXN2",
            "TTLL10",
            "PTH2",
            "SULT6B1",
            "HSPB9",
            "OR13J1",
            "DUOX2",
            "DNASE2B",
            "OR7G1",
            "OR2W1",
            "CST9",
            "TMPRSS6",
            "TEX101",
            "CYP4A22",
            "NME3",
            "RGS13",
            "TOMM20L",
            "OR4C3",
            "ANTXRL",
            "POU4F3",
            "PRDM7",
            "RHEBL1",
            "HCAR2",
            "OR4F4",
            "H2BW2",
            "OR11H12",
            "CT45A6",
            "PLCXD1",
            "TINAG",
            "AKR7A2",
            "SSX2",
            "NCF1C",
            "RAD21L1",
            "AIFM2",
            "DEFB110",
            "ADGRG7",
            "SPATA45",
            "MSGN1",
            "KRTAP6-2",
            "CLDN25",
            "SERPINB10",
            "CMTR1",
            "ZP1",
            "LINC00523",
            "TAS2R16",
            "TOPAZ1",
            "OR2T5",
            "RAG2",
            "NOMO2",
            "MUC2",
            "SPATA31A6",
            "NAP1L4",
            "GYS1",
            "SBSN",
            "H4C12",
            "OR4F5",
            "SEC14L3",
            "DPEP3",
            "FAM47A",
            "OPTC",
            "DEFA6",
            "FAM138D",
            "CYP4F29P",
            "CYP4Z2P",
            "PRR23C",
            "IGSF22",
            "H2AC25",
            "OXT",
            "UGT1A1",
            "SLC25A51P1",
            "CLEC4G",
            "PDE6A",
            "CYP2W1",
            "ITLN1",
            "NLRP9",
            "CYCSP52",
            "NR5A1",
            "PRB4",
            "RBM38",
            "REC114",
            "ABCG5",
            "PNLIP",
            "SYCP3",
            "FERD3L",
            "TDRG1",
            "LINC00244",
            "CT45A3",
            "FAM170A",
            "RIMBP3C",
            "SRD5A2",
            "ANGPTL6",
            "KRTAP20-4",
            "OR13C3",
            "AGBL1",
            "ESPNL",
            "TASOR",
            "FAM209B",
            "LYPD4",
            "MYO7B",
            "TMEM179",
            "REG1B",
            "DNASE1L3",
            "LINC00479",
            "ACSM4",
            "CLCA3P",
            "SPTSSB",
            "LINC02915",
            "RBP2",
            "TSSK1B",
            "SEPTIN14",
            "PRLH",
            "DNPH1",
            "NLRP13",
            "ACTA1",
            "APOBEC3A",
            "UNC45B",
            "C9orf57",
            "KRTAP19-6",
            "CGB8",
            "TMOD1",
            "GPX6",
            "LINC01565",
            "TAAR2",
            "OR1J2",
            "SLC10A2",
            "MSLN",
            "OBSCN",
            "TBK1",
            "LY6G5C",
            "OR11H4",
            "NANOS1",
            "ARGFX",
            "IGDCC4",
            "OR2T29",
            "ZSCAN10"
        ],
        "Coefficient": [
            -0.8554126201875386,
            0.6118467091873819,
            0.5069468036970898,
            0.48532836790760814,
            0.4738096897033487,
            0.4704749068872965,
            -0.4693044183705947,
            0.45619887564979494,
            0.4156121570087176,
            0.4078695751431471,
            0.3960901307557597,
            -0.39279490366480657,
            0.38636535211198597,
            -0.3857102423378238,
            0.3855455234148727,
            0.3846376950675805,
            -0.37525811703608886,
            0.37228883247290245,
            0.37044154272653057,
            -0.3696893666532802,
            -0.3570650740195058,
            0.35420643623218157,
            0.3416639065619058,
            0.338982905730469,
            -0.33875900420883265,
            0.3365069766313258,
            0.3363288386588548,
            0.333250662113638,
            -0.33000676688707686,
            -0.3297539735827746,
            -0.32874440581800074,
            0.3254669306669092,
            -0.32485302870499144,
            -0.32046459278749956,
            -0.31956505363555765,
            -0.3192032633863017,
            -0.3175700615678046,
            -0.31555672909514976,
            -0.31475365047965304,
            -0.31413591238783983,
            -0.3128039188939403,
            -0.31271326422453266,
            -0.3105072017403758,
            -0.310191436480287,
            0.3097140098501535,
            0.30945588831215337,
            -0.30623011546564016,
            0.2982892103009632,
            0.29698604599852496,
            0.29631677710107884,
            0.2959176560260665,
            0.2954477185364121,
            -0.2927624975743418,
            0.29275282663668234,
            0.28943173381869963,
            0.2861964003804867,
            -0.2845714961282485,
            -0.283122567377293,
            0.2785987845094592,
            -0.2779939684371558,
            0.2777997571472654,
            0.27676118187721155,
            -0.27228009879777565,
            0.27171460587151086,
            0.2709371724711346,
            -0.27091547524157533,
            -0.2691459581993795,
            -0.2690799213680101,
            -0.2689817749408273,
            -0.2687354953431295,
            0.26606427632085106,
            -0.26507451911241015,
            -0.26500839929683284,
            0.2632486325623039,
            0.2632075798389756,
            0.2630740826109435,
            0.26284657825623264,
            0.26276117757950307,
            -0.26074285733534247,
            -0.25985257535414985,
            -0.25908079102371795,
            0.2590322172435957,
            0.2589088108007487,
            -0.25732226080745985,
            -0.2570726261972659,
            0.25692326289431155,
            -0.2551048078217558,
            0.25085173985253306,
            -0.24921772342603404,
            -0.24900957113659208,
            -0.2473670867658537,
            0.24715494674725405,
            -0.2457843575171488,
            -0.2454639318204907,
            0.244843568402999,
            0.2447027789174922,
            -0.24420790681606572,
            0.24233915723056149,
            0.2393632649712818,
            -0.23925114582106502,
            0.23862381577409927,
            -0.23719817601059545,
            -0.23438959300574036,
            0.23326807076537778,
            -0.2324541841986572,
            -0.23158819293013028,
            -0.23116636156473197,
            0.22784367623506488,
            -0.2275235102591784,
            0.22740295896933005,
            -0.22550542541349902,
            -0.22488546106755022,
            -0.2248320874120877,
            -0.22327449763287044,
            -0.22290750500425105,
            0.22130886622787244,
            -0.22048929369519055,
            0.2203248501182218,
            0.21984269843872087,
            -0.21935727293657828,
            -0.2183952234390431,
            -0.21793419178351547,
            -0.21770499729672776,
            -0.21705866763368684,
            0.2148859070058694,
            -0.2148637668035193,
            0.21481318935601462,
            -0.21256840378692296,
            -0.2120756063593504,
            -0.21125899605794213,
            -0.21067135227576622,
            0.21058136491986737,
            0.2094592816315786,
            -0.20928023689499547,
            -0.20864668192753252,
            -0.20864027280596895,
            -0.20589166494472066,
            -0.20542614089320735,
            0.20347247202407284,
            -0.20287384990288682,
            -0.20248853836975128,
            0.20037022527337237,
            0.20036802220377065,
            0.19933730621526285,
            -0.19916187473387323,
            0.19838920814412786,
            0.19662466374638077,
            0.19594267154266093,
            -0.1951324541687618,
            0.19512963087567242,
            0.19494866514816367,
            0.1949283086847553,
            -0.19474294141082804,
            0.1938420402770134,
            -0.19322794216530356,
            -0.19113082686326988,
            0.18834308812436726,
            -0.18813955337260793,
            -0.1872792791435753,
            0.186476446814032,
            -0.18587814129382962,
            0.18500986169254552,
            0.18369588476323362,
            0.18148312612440587,
            -0.17933374550238837,
            0.1758326648685003,
            -0.17534270243924915,
            -0.17386914308589208,
            -0.17377369181905555,
            0.17370931267134054,
            0.1735491660667676,
            0.17333602360017047,
            0.17269578123096288,
            -0.17258313391427882,
            -0.17252873159389717,
            0.172238308505207,
            0.1709269175803016,
            -0.1708918208829954,
            -0.17064125388305562,
            0.1702819789222707,
            0.1678387339760715,
            0.16774061381530084,
            -0.16755477950846306,
            -0.16750353556378642,
            -0.16715646873878703,
            -0.16500035303994126,
            -0.16377590417713375,
            -0.1635308248919516,
            0.1630186300592003,
            0.1622192420411439,
            -0.16198247812355543,
            0.15968574458102366,
            -0.15862885682972816,
            -0.15853855426241792,
            -0.15796974030737962,
            -0.15774834276011768,
            -0.15769680967256042,
            -0.15761705624277064,
            -0.15756428671618294,
            -0.15585979667159677,
            -0.15579862464552105,
            0.15548977346531456,
            0.15531011922214277,
            0.1549835865532955,
            0.1546522407993244,
            -0.15334477446975872,
            0.15317119341635094,
            0.15248053565594033,
            0.15241644666011858,
            0.15182997283328398,
            0.15162539366069744,
            0.15136556461807346,
            -0.150895490508268,
            0.15081821401000695,
            -0.14909376157757612,
            -0.14842873788155958,
            -0.14836315081690196,
            0.14693724825849247,
            0.1465640295293839,
            -0.14639698913958818,
            0.14623147735379105,
            -0.14550036830398902,
            -0.14496229456202073,
            -0.14333388357196677,
            0.1432702820697139,
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