{
    "significant_genes": {
        "Variable": [
            "ELK3",
            "PRR20A",
            "FAM69B",
            "ZMIZ1",
            "SESN3",
            "CPNE9",
            "OR13J1",
            "MANEA",
            "KLF3",
            "NFKB2",
            "UBE2J1",
            "R3HDM2",
            "MYO1B",
            "MEST",
            "C1orf63",
            "TBX6",
            "CDA",
            "TUBA3E",
            "MYCBPAP",
            "FAM3D",
            "FAM53C",
            "GLDN",
            "SPATA20",
            "TMEM125",
            "RABL2A",
            "GPC6",
            "TMEM123",
            "C19orf76",
            "ZNF544",
            "GPR37",
            "APOC2",
            "EIF4E",
            "EMR3",
            "LRRC55",
            "MGC23270",
            "SMN1",
            "OR2G6",
            "GSTT1",
            "GAR1",
            "MFHAS1",
            "CDC42BPG",
            "SLC38A4",
            "MTHFSD",
            "ASTE1",
            "FAM106A",
            "C16orf73",
            "C15orf17",
            "RNF5P1",
            "PDE6C",
            "HEY2",
            "C7orf54",
            "OR1Q1",
            "KRTAP4-8",
            "WASH5P",
            "KRTAP5-11",
            "RGS7",
            "CNGA2",
            "RFPL1S",
            "HOXC11",
            "ABCA2",
            "LRIG3",
            "KRT33B",
            "KCNH7",
            "SPTLC3",
            "LOC100268168",
            "OR3A2",
            "ARSG",
            "LOC100132724",
            "SLC35F4",
            "TRPC5",
            "SH2D7",
            "ASAP1IT1",
            "KCNK18",
            "ARPP21",
            "LCE3E",
            "ITPKC",
            "TTLL13",
            "SLC7A5P1",
            "TNPO2",
            "ZAR1",
            "BMP15",
            "CLDN17",
            "OR5M11",
            "LMOD2",
            "XKR6",
            "GLRA1",
            "S100A13",
            "SPCS2",
            "CTSK",
            "PPP1R11",
            "OBP2B",
            "ODC1",
            "AQP11",
            "MYCN",
            "LOC643923",
            "MGC42105",
            "IL1RAPL1",
            "TXNRD3IT1",
            "PCDHB19P",
            "SNORD94",
            "TRIT1",
            "NOVA1",
            "OR1S1",
            "YTHDF1",
            "IQCF3",
            "HSPB2",
            "LOC340017",
            "OR7E156P",
            "NAP1L2",
            "CAGE1",
            "TNFRSF13B",
            "GPR15",
            "FBN2",
            "LRRC14B",
            "CAMK2B",
            "LOC100129055",
            "PLA2G10",
            "CHST4",
            "TRIM43",
            "KRTAP19-3",
            "WFDC10A",
            "HIST1H3E",
            "GMPR2",
            "CCDC144NL",
            "EGR4",
            "SNORA62",
            "TKTL2",
            "NPR2",
            "GBX1",
            "CREB3",
            "GLIPR1L2",
            "CSHL1",
            "SNORA45",
            "KRTAP20-4",
            "PCDHGA8",
            "EDIL3",
            "SLCO6A1",
            "VCX2",
            "PCDHB6",
            "LOC285847",
            "GIMAP7",
            "OR51E2",
            "LOC730668",
            "C8orf47",
            "TRIM60",
            "TAS2R8",
            "IGFL4",
            "ANKRD34B",
            "CHRNA4",
            "DEFB106A",
            "OR2T27",
            "PRB1",
            "CHIT1",
            "OR2H1",
            "ACCSL",
            "ZSWIM2",
            "TXNDC2",
            "DMC1",
            "FNDC4",
            "CYP4Z1",
            "PDE6H",
            "FNDC8",
            "CYP2A6",
            "SLTM",
            "SFTPA2",
            "ZNF560",
            "PNOC",
            "CPN1",
            "LOC729609",
            "NXF4",
            "WISP3",
            "TUBB1",
            "CYP4F2",
            "C3orf14",
            "EN2",
            "LOC645431",
            "UOX",
            "?|653553",
            "MRPL42P5",
            "SCARNA23",
            "TAS2R30",
            "KRTAP24-1",
            "CST11",
            "SNORA66",
            "SPESP1",
            "IL4",
            "SNORA2B",
            "SHH",
            "CASQ1",
            "OR52D1",
            "ASPHD2",
            "PIWIL3",
            "TIMD4",
            "POU4F3",
            "MSLN",
            "TMEM154",
            "C4orf45",
            "HLA-DQB1",
            "DGKB",
            "FCGR3B",
            "OR5R1",
            "EGFLAM",
            "KIR2DL3",
            "SCARNA12",
            "RNF125",
            "GSTM1",
            "GRAPL",
            "IGFL2",
            "FLJ41941",
            "KCNA4",
            "INTS4L2",
            "ANKRD7",
            "CCNYL1",
            "OR2T29",
            "RGS22",
            "RPAP3",
            "OR5K2",
            "ZDHHC22",
            "CHP2",
            "TCP10L2",
            "IL17A",
            "RAB40AL",
            "C1QTNF9B",
            "C1orf230",
            "SPACA5",
            "UGT8",
            "P2RY8",
            "TTTY7",
            "SPINT3",
            "OR1E2",
            "HPYR1",
            "TAS2R41",
            "C20orf201",
            "FGF8",
            "C7orf66",
            "KCNN3",
            "SNORA70B",
            "ZFP91-CNTF",
            "ABP1",
            "C1orf189",
            "OR52A5",
            "DPRX",
            "FEV",
            "MEIS3P1",
            "DCAF12L1",
            "LOC646627",
            "OR13C8",
            "ITGA2",
            "TBX4",
            "OR2T2",
            "C21orf90",
            "EDC3",
            "BRAP",
            "CRISP1",
            "CDH10",
            "LOC644145",
            "ZFYVE27",
            "HIST1H4B",
            "C6orf176",
            "UNC5C",
            "SOX21",
            "ID2B",
            "C8orf86",
            "OTC",
            "LSM14B",
            "CAPN11",
            "STK39",
            "SEPP1",
            "GABRR3",
            "SPDYE2",
            "FAM71F1",
            "SCGBL",
            "RNF151",
            "ARMCX6",
            "HSPA1B",
            "GSDMA",
            "DIO3",
            "CBWD2",
            "PKD2L2",
            "CA14",
            "SNORA4",
            "C5orf35",
            "PPEF2",
            "SCARNA27",
            "A4GNT",
            "REPS1",
            "APPL2",
            "OR6K2",
            "NOX1",
            "LOC283050",
            "PCDHGB2",
            "ZNF521",
            "FBXW8",
            "SLC6A20",
            "UCP1",
            "C5orf52",
            "HERC2P4",
            "CADPS",
            "C9orf173",
            "HIST2H3C",
            "MEGF10",
            "PABPC1L2B",
            "CACNA1B",
            "FLJ40292",
            "LRRIQ3",
            "SPRR2F",
            "TTLL8",
            "HFE",
            "PNLIP",
            "EN1",
            "SAGE1",
            "CLEC4G",
            "MGC16025",
            "ZNF883",
            "HIST1H4A",
            "VPS37C",
            "NGB",
            "VSTM1",
            "DNAJB8",
            "CDC27",
            "SLC36A3",
            "NEK10",
            "CSPG5",
            "FST",
            "LOC286238",
            "KIAA1210",
            "NDP",
            "ACTN3",
            "MTVR2",
            "DCLK3",
            "TNFRSF11B",
            "ECEL1",
            "ATL1",
            "POU6F2",
            "GPRIN2",
            "ARSE",
            "F2RL2",
            "OR52W1",
            "HIST1H2AG",
            "SLC16A6",
            "C10orf131",
            "FMO5",
            "NR5A1",
            "C20orf70",
            "OR5K3",
            "SLC38A8",
            "C17orf78",
            "WHAMM",
            "CD300LD",
            "QRSL1",
            "LOC392196",
            "CYCSP52",
            "NHLRC3",
            "SPATA22",
            "CC2D1B",
            "GAB4",
            "SNAR-F",
            "STK32A",
            "C3orf49",
            "ZNF341",
            "CDH8",
            "AMHR2",
            "POF1B",
            "GABRR2",
            "ACOT13",
            "LOC284661",
            "NOS2",
            "OR2T3",
            "ST7OT2",
            "TDH",
            "CLLU1OS",
            "SNORD15A",
            "DERL3",
            "PDCD4",
            "TXNDC8",
            "COL9A3",
            "OR5AK2",
            "GDF5",
            "HCG22",
            "CAPN9",
            "TMEM151A",
            "CA12",
            "SLC9A10",
            "GRM3",
            "FAM135B",
            "RBMY1B",
            "APOA1",
            "TLK2",
            "LOC649330",
            "CLEC4M",
            "SLITRK3",
            "LOC100240734",
            "UFSP1",
            "SLC44A2",
            "FAM138D",
            "OPN1MW",
            "E2F3",
            "TTC29",
            "?|100130426",
            "HOXA6",
            "C20orf173",
            "DSPP",
            "OR10G2",
            "ST7L",
            "C20orf166",
            "OOEP",
            "FGF16",
            "PNLDC1",
            "CRYBA1",
            "DCX",
            "NAT9",
            "FGF4",
            "FAM101A",
            "PGK2",
            "ACP5",
            "PCDHGB7",
            "MSLNL",
            "KCTD14",
            "GIPC3",
            "SNORA16B",
            "EPYC",
            "C11orf42",
            "C4orf23",
            "KCNJ6",
            "LOC100132354",
            "OR10T2",
            "PTX3",
            "HIST2H2BF",
            "ZIM2",
            "OR52L1",
            "CPLX4",
            "MPHOSPH6",
            "TBK1",
            "C15orf26",
            "RFPL3",
            "CLDN25",
            "IFNA8",
            "RDM1",
            "DYTN",
            "CRHR2",
            "HIST1H3F",
            "SEPT7L",
            "PCDH17",
            "KRTAP13-4",
            "SMPX",
            "OR2T8",
            "C11orf34",
            "ANTXRL",
            "TMEM229A",
            "LOC219347",
            "CHRNG",
            "ESPNL",
            "COX8C",
            "FUNDC2P2",
            "FOXE3",
            "LRRC41",
            "C14orf19",
            "LOC285194",
            "NANOS1",
            "AKAP4",
            "MAEA",
            "LRRC10B",
            "OR11H12",
            "HERPUD2",
            "IL1F6",
            "TPH2",
            "CLEC4C",
            "SPHK1",
            "RIMKLB",
            "CREB3L4",
            "C7orf28B",
            "SNORA1",
            "RNASE8",
            "DUPD1",
            "SLC32A1",
            "STAR",
            "UGT2B28",
            "PROKR1",
            "C1orf227",
            "DUSP6",
            "GPR150",
            "LOC641367",
            "SIGLEC12",
            "CA3",
            "OR4S1",
            "SLC2A7",
            "BOLL",
            "BARX1",
            "PPAN-P2RY11",
            "FAM74A3",
            "BCCIP",
            "RRAD",
            "CMTM5",
            "MMP8",
            "GRIK4",
            "CCDC146",
            "IL24",
            "OR5E1P",
            "SCGB1D4",
            "OTOS",
            "SOX5",
            "GPR88",
            "IGLON5",
            "MB",
            "TRIML1",
            "PDE4B",
            "C6orf58",
            "OR3A3",
            "FLJ26850",
            "OR14I1",
            "LOC284788",
            "MCF2",
            "GTF2A1L",
            "TMEM132D",
            "CLRN2",
            "PLP1",
            "NEU2",
            "HIST1H3H",
            "FEZF2",
            "SPDYE4",
            "MRAP",
            "NRAP",
            "BAHD1",
            "STAMBP",
            "C1orf194",
            "ZNF727",
            "DDX11L2",
            "FLJ37453",
            "C1orf185",
            "AKR1B15",
            "METAP1",
            "NCRNA00207",
            "SPACA4",
            "MGAT3",
            "PCGEM1",
            "TAS1R2",
            "C15orf38",
            "SULT1A1",
            "LOC441666",
            "PTPLAD2",
            "NOTO",
            "ZNF100",
            "KIAA0408",
            "RNASE13",
            "TEKT4",
            "NKX2-2",
            "SNORA51",
            "NCRNA00110",
            "ITGB6",
            "NOS3",
            "SNORA56",
            "FRG1B",
            "CYP2C8",
            "ZNF667",
            "C19orf57",
            "NUDT9P1",
            "ALPP",
            "PPARGC1B",
            "METTL10",
            "ZNF565",
            "ANKRD54",
            "C5orf30",
            "ARHGEF38",
            "SLC39A12",
            "KRTAP5-2",
            "LOC100240726",
            "GYPA",
            "PRHOXNB",
            "TBC1D3C",
            "CHRNA10",
            "PCDHB16",
            "DSG4",
            "ROBO1",
            "LOC201651",
            "SNORD90",
            "SNAR-H",
            "RBP3",
            "DNAH2",
            "TSSK2",
            "KRTAP21-1",
            "DEFB114",
            "LOC653545",
            "SPINK14",
            "NMS",
            "OR4S2",
            "KRTAP22-1",
            "SNAR-A3",
            "CCDC157",
            "PSD2",
            "TEX28",
            "P2RX6P",
            "SNORD88C",
            "SNAR-D",
            "KRTAP20-3",
            "SNORD16",
            "SNORD116-19",
            "KRTAP6-1",
            "SNORD115-20",
            "KRTAP20-1",
            "SNORA30",
            "DEFB113"
        ],
        "Coefficient": [
            6.09070730601544,
            -5.565396717558571,
            3.399938749943062,
            3.27609351090184,
            3.109823708678718,
            -3.0647580789546898,
            -2.9397205491264926,
            2.926440315387523,
            2.903305788929632,
            -2.7942920406657312,
            2.769139995557254,
            2.7384867023121426,
            2.705699647056369,
            2.7007561005020664,
            -2.691375611507828,
            -2.5677395137255474,
            2.4735923067559398,
            -2.4688689591661097,
            -2.4637220363757004,
            2.3990050105800047,
            -2.381427856563189,
            -2.356974169196455,
            -2.3162648158243466,
            -2.284673285993179,
            -2.0858594653436424,
            2.07202291309878,
            2.0470068439994247,
            -2.0425203915518333,
            2.0249773176060164,
            2.0154975138173272,
            -1.9833748086208902,
            -1.955496077287928,
            1.9143393202292796,
            1.912978702955298,
            1.9072600024155795,
            1.860798669492681,
            -1.8511338103837112,
            1.8488801237136707,
            -1.8242580776031945,
            1.8231503343060396,
            -1.8093452197066275,
            1.804958067658222,
            -1.8031361871428273,
            1.7987477644225902,
            -1.7944052156737436,
            1.792322286360427,
            -1.7600322225376004,
            -1.7373629996436433,
            1.7073170305862821,
            1.7008334305006936,
            -1.6992955061526303,
            -1.6747329976193865,
            1.657857321614158,
            -1.6498681505883943,
            1.637878366390629,
            1.6267528701391434,
            1.625877707209265,
            1.617689690938154,
            -1.6081620318436158,
            1.6059861735397472,
            1.6049722005330382,
            1.594893995018065,
            1.5941380419051112,
            1.5848030385392728,
            -1.5623985464652062,
            1.549865466230052,
            1.5233724148812413,
            -1.5127843130394842,
            1.4962345593142554,
            1.491386488595761,
            -1.4653404648409278,
            -1.4621590083618397,
            1.4589541626953735,
            1.4322295705622996,
            1.3963474608901765,
            -1.391737649551345,
            -1.3759484677751432,
            -1.3754343526782031,
            -1.3377044544408432,
            -1.3305132646326194,
            -1.3246586181649491,
            1.321169130845238,
            1.3175469761011849,
            1.31147487851598,
            1.3070967227993673,
            -1.2965276053972021,
            -1.2944351626520998,
            -1.2806215713792066,
            -1.2799948118257787,
            1.2670631122602711,
            -1.2594662863851467,
            1.2583948455753649,
            1.2561624372964537,
            1.2436355061640447,
            -1.2352323444169315,
            -1.2309533097970509,
            -1.2146232824154304,
            -1.2093416465979434,
            1.205562428177374,
            1.1948216421861,
            -1.194808626594385,
            1.1937609576063202,
            -1.1897049675040765,
            -1.1805067557274393,
            1.174004439529544,
            -1.1671309030971482,
            1.1593125010814898,
            -1.1430990913783865,
            1.1385568618411452,
            1.1379306085451828,
            -1.1311880344624414,
            1.1252518359122594,
            1.1242364393165483,
            -1.1108297823629458,
            -1.1081115336829328,
            -1.1009565456278605,
            -1.095652109343665,
            -1.071355275881687,
            -1.0703505554352883,
            1.0661244625490731,
            1.0604510749758786,
            1.0558387771292543,
            1.0536590467994884,
            -1.051405943889355,
            -1.030554830831972,
            1.0296704568897748,
            1.026853651046591,
            1.0235593330094936,
            -1.0052439462708183,
            -0.9905467701199171,
            -0.9858868777972479,
            0.9795852098489989,
            0.9754048721832731,
            0.9707657756127839,
            -0.966864378734136,
            0.9652130803869392,
            -0.9491795689914165,
            0.9449147005383813,
            0.9293206498899018,
            -0.9291376106478696,
            0.9275672943639989,
            0.9223668308124962,
            -0.9188623145655913,
            0.9165057339502362,
            -0.9163350348486594,
            -0.9120226142439821,
            -0.9118835605431114,
            0.9090658968495192,
            0.9087051360450211,
            -0.906150752925645,
            0.9013943942753712,
            -0.8979843185973988,
            -0.8885199355661145,
            -0.8880475885405293,
            0.8862766425785616,
            0.8808885121750908,
            0.8808085982949546,
            0.8675362353005553,
            0.8673226034923641,
            -0.8582895814248699,
            -0.8553954187985752,
            -0.851550743136329,
            -0.8493823349066673,
            -0.8443829980024885,
            -0.829555477736227,
            0.8274263106574132,
            -0.8240995621028784,
            0.8205551457295933,
            0.8191236047828674,
            0.8186618595688638,
            0.8155006406096282,
            -0.8147537473935468,
            0.8145858258651169,
            0.8063151716743967,
            -0.7992856206029622,
            -0.7981996646493998,
            -0.7862206906692505,
            -0.7849702806545145,
            -0.782374355125208,
            0.7810431748615456,
            0.7714432755691604,
            -0.7707224198055573,
            -0.760098490897134,
            0.759163295136363,
            0.755502210935742,
            0.754802193853353,
            0.7466362265323389,
            0.7464567579913541,
            -0.7389644617152102,
            -0.7365918657254368,
            -0.734900175920247,
            -0.7348478685440175,
            -0.7346215476830119,
            0.724049402577756,
            -0.7222324977886205,
            0.7214730225805274,
            0.7203414786315504,
            0.7145848738029504,
            0.7076740667739122,
            0.6983921476145311,
            0.6922715240714695,
            0.6921746925693312,
            -0.683884708217604,
            -0.6835736791836513,
            0.6813945017640871,
            0.6797117311817261,
            0.6781200312359529,
            0.6762331097232018,
            -0.6751493343882793,
            0.6729293284028741,
            0.6694177448451214,
            0.6667048403692655,
            0.6578903489234109,
            -0.6558299993929627,
            0.6547747119398827,
            0.6545873582233968,
            0.6523474536293543,
            0.6460390609579831,
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