{
    "significant_genes": {
        "Variable": [
            "ELK3",
            "PRR20A",
            "FAM69B",
            "CPNE9",
            "C1orf63",
            "OR13J1",
            "R3HDM2",
            "NFKB2",
            "ZMIZ1",
            "KLF3",
            "TBX6",
            "CDA",
            "UBE2J1",
            "SESN3",
            "MYO1B",
            "MYCBPAP",
            "GPC6",
            "SPATA20",
            "FAM3D",
            "GLDN",
            "TMEM125",
            "MANEA",
            "ZNF544",
            "EIF4E",
            "MGC23270",
            "RNF5P1",
            "MEST",
            "SMN1",
            "ARSG",
            "TMEM123",
            "C15orf17",
            "C16orf73",
            "PDE6C",
            "C19orf76",
            "RABL2A",
            "APOC2",
            "MFHAS1",
            "TUBA3E",
            "KRTAP4-8",
            "CNGA2",
            "FAM53C",
            "MTHFSD",
            "GPR37",
            "GSTT1",
            "RFPL1S",
            "FAM106A",
            "RGS7",
            "SPTLC3",
            "HOXC11",
            "SLC38A4",
            "ASAP1IT1",
            "KCNK18",
            "OR2G6",
            "TNPO2",
            "EMR3",
            "OR1Q1",
            "PCDHB19P",
            "ARPP21",
            "KRT33B",
            "KRTAP5-11",
            "TRPC5",
            "TTLL13",
            "MYCN",
            "SNORD94",
            "ABCA2",
            "C7orf54",
            "HEY2",
            "LOC100132724",
            "ITPKC",
            "PPP1R11",
            "IL1RAPL1",
            "ZAR1",
            "LOC100268168",
            "OR5M11",
            "GLRA1",
            "WASH5P",
            "SPCS2",
            "LOC340017",
            "?|653553",
            "OR1S1",
            "TXNDC2",
            "EGR4",
            "LOC100129055",
            "SLC35F4",
            "CTSK",
            "LOC643923",
            "CCDC144NL",
            "SLC7A5P1",
            "TNFRSF13B",
            "LRIG3",
            "CDC42BPG",
            "CHIT1",
            "CLDN17",
            "KRTAP19-3",
            "BMP15",
            "TXNRD3IT1",
            "KCNH7",
            "ASTE1",
            "LCE3E",
            "GRAPL",
            "TRIT1",
            "CPN1",
            "UGT8",
            "GAR1",
            "LRRC14B",
            "SNORA45",
            "PCDH17",
            "CHST4",
            "TKTL2",
            "AQP11",
            "LRRC55",
            "WISP3",
            "TRIM60",
            "OR3A2",
            "PLA2G10",
            "LMOD2",
            "HIST1H3E",
            "SLC38A8",
            "UOX",
            "OR7E156P",
            "OR2H1",
            "FGF8",
            "DMC1",
            "S100A13",
            "SH2D7",
            "OBP2B",
            "MGC42105",
            "LRRIQ3",
            "TRIM43",
            "DEFB106A",
            "STK32A",
            "FCGR3B",
            "SCARNA23",
            "LOC649330",
            "EN1",
            "IQCF3",
            "P2RY8",
            "WFDC10A",
            "CAMK2B",
            "KRTAP24-1",
            "OR52D1",
            "FBXW8",
            "RNF125",
            "FNDC4",
            "XKR6",
            "LOC285847",
            "SNORA66",
            "HSPB2",
            "ANKRD34B",
            "ACCSL",
            "INTS4L2",
            "A4GNT",
            "ZFYVE27",
            "FBN2",
            "OR51E2",
            "TCP10L2",
            "FNDC8",
            "SHH",
            "IGFL4",
            "GLIPR1L2",
            "CASQ1",
            "GPR15",
            "WHAMM",
            "ODC1",
            "SLCO6A1",
            "TIMD4",
            "RPAP3",
            "CST11",
            "PCDHB6",
            "IL17A",
            "EDIL3",
            "ANKRD7",
            "CSHL1",
            "SPESP1",
            "CDH10",
            "NDP",
            "TUBB1",
            "PRB1",
            "NAP1L2",
            "HPYR1",
            "NEK10",
            "ZSWIM2",
            "C20orf201",
            "GBX1",
            "SNORA62",
            "CYP4F2",
            "NOVA1",
            "ZDHHC22",
            "SNORA2B",
            "OR13C8",
            "LOC645431",
            "ASPHD2",
            "IGFL2",
            "OR52A5",
            "KRTAP20-4",
            "CAPN11",
            "PDE6H",
            "CYP2A6",
            "FEV",
            "CREB3",
            "C4orf45",
            "TAS2R8",
            "C1orf189",
            "BICD1",
            "PCGEM1",
            "YTHDF1",
            "OR5K2",
            "OR2T29",
            "PIWIL3",
            "MEGF10",
            "APPL2",
            "C10orf131",
            "NXF4",
            "COL9A3",
            "TNFRSF11B",
            "DGKB",
            "CAGE1",
            "GPRIN2",
            "EN2",
            "PCDHGA8",
            "DCLK3",
            "TAS2R41",
            "SPINT3",
            "C1QTNF9B",
            "SFTPA2",
            "LOC730668",
            "CYP4Z1",
            "CHP2",
            "GAB4",
            "SNAR-F",
            "VCX2",
            "LRRC41",
            "SMG5",
            "C3orf14",
            "KIAA1033",
            "LOC729609",
            "OR2T27",
            "ID2B",
            "NPR2",
            "RGS22",
            "CRHR2",
            "HERC2P4",
            "IL4",
            "KCNN3",
            "CACNA1B",
            "RNF151",
            "SNORA70B",
            "NEU2",
            "CRISP1",
            "OR10T2",
            "PNOC",
            "GSTM1",
            "CSPG5",
            "ABP1",
            "RAB40AL",
            "HSPE1",
            "OR5R1",
            "CBWD2",
            "MSLN",
            "SLTM",
            "HSPA1B",
            "LOC285194",
            "SEPP1",
            "LOC646627",
            "OR2T2",
            "CHRNA4",
            "PABPC1L2B",
            "HCG22",
            "ZNF560",
            "E2F3",
            "OTC",
            "PCDHGB2",
            "AMHR2",
            "C7orf66",
            "CLEC4G",
            "TAS2R30",
            "DSPP",
            "GMPR2",
            "ACTN3",
            "NHLRC3",
            "POU4F3",
            "ECEL1",
            "GABRR3",
            "TM2D2",
            "MMP8",
            "UCP1",
            "OR6K2",
            "HERPUD2",
            "HIST1H4B",
            "LOC644145",
            "CCNYL1",
            "SAGE1",
            "OR1E2",
            "KIR2DL3",
            "SPATA22",
            "SCARNA27",
            "SOX5",
            "TMEM151A",
            "C5orf52",
            "NCRNA00110",
            "FST",
            "FLJ41941",
            "MTVR2",
            "ZNF883",
            "C3orf49",
            "LOC100240734",
            "ZNF341",
            "CA12",
            "OR2T8",
            "NOTO",
            "PPEF2",
            "C8orf47",
            "SCGBL",
            "IL28A",
            "DNAJB8",
            "RFPL3",
            "C15orf38",
            "ATL1",
            "ESPNL",
            "POU6F2",
            "RLN3",
            "CLEC4C",
            "BCCIP",
            "BRAP",
            "FAM101A",
            "SNORA4",
            "ZFP91-CNTF",
            "POF1B",
            "C1orf87",
            "RBMY1B",
            "HIST1H2AG",
            "MGC16025",
            "RIMKLB",
            "SPDYE2",
            "VSTM1",
            "SLC36A3",
            "IZUMO1",
            "CBWD3",
            "CAPN9",
            "CD300LD",
            "POC1B",
            "PGK2",
            "HIST2H2BF",
            "MRPL42P5",
            "CRYBA1",
            "OR2T3",
            "LOC219347",
            "SLC2A7",
            "TTTY7",
            "MEIS3P1",
            "SLITRK3",
            "NAP1L4",
            "RRAD",
            "PKD2L2",
            "STAG3L2",
            "LSM14B",
            "MUC13",
            "TXNDC8",
            "SPACA5",
            "TBX4",
            "C20orf70",
            "CA14",
            "OR52W1",
            "CLEC4M",
            "GSDMA",
            "SLC6A20",
            "SLC44A2",
            "CYCSP52",
            "FAM48B1",
            "LOC283050",
            "GPR150",
            "C21orf90",
            "RPS6KA6",
            "LRP5L",
            "UGT2B28",
            "HIST1H4A",
            "CADPS",
            "OR10G2",
            "GABRR2",
            "BARX1",
            "CLRN2",
            "TMEM154",
            "SDC4",
            "ST7OT2",
            "EDC3",
            "PPAN-P2RY11",
            "FZD8",
            "SCGB1D4",
            "ACOT13",
            "HFE",
            "NOX1",
            "REPS1",
            "DIO3",
            "NGB",
            "KIAA1210",
            "TLK2",
            "FOXE3",
            "LOC392196",
            "CREB3L4",
            "IGLON5",
            "C5orf35",
            "HIST2H3C",
            "C8orf86",
            "LOC284788",
            "DUPD1",
            "TMEM132D",
            "SEPT7L",
            "KCNA4",
            "MGC34034",
            "ARMCX6",
            "RDM1",
            "C20orf166",
            "CXorf50B",
            "STK39",
            "APOA1",
            "LOC100132354",
            "ST7L",
            "SPHK1",
            "ITGA2",
            "DCAF12L1",
            "CPLX4",
            "KCNJ6",
            "OPN1MW",
            "OR4S1",
            "VPS37C",
            "C20orf173",
            "EIF5A2",
            "SERPINB1",
            "SYCE1",
            "OR3A3",
            "DSG4",
            "L3MBTL3",
            "MMP21",
            "SPDYE4",
            "LCN8",
            "KIAA1751",
            "NR5A1",
            "LOC100133957",
            "PRHOXNB",
            "OR14I1",
            "SOX21",
            "PAPL",
            "THBS4",
            "EPYC",
            "MGAT3",
            "CDH8",
            "OR2T34",
            "FAM74A3",
            "PLD1",
            "OR52L1",
            "TMEM229A",
            "SPRR2F",
            "POU2F3",
            "C9orf173",
            "C1orf61",
            "C6orf176",
            "KLF12",
            "PPARGC1B",
            "COL20A1",
            "OR4S2",
            "GSTT2",
            "ZIM2",
            "SYT2",
            "GIMAP7",
            "ARHGEF3",
            "CELA3A",
            "SLC32A1",
            "LOC100240726",
            "ELAC1",
            "SNORA1",
            "QRSL1",
            "KCTD14",
            "NUDT9P1",
            "OOEP",
            "DYTN",
            "SNORA16B",
            "CA3",
            "ZNF707",
            "LOC100133669",
            "KRTAP5-2",
            "JMJD4",
            "ARSE",
            "ALG1L",
            "C1orf68",
            "ZNF79",
            "GRM3",
            "SMPX",
            "FAM71F1",
            "CLLU1OS",
            "ZNF534",
            "LOC286238",
            "CYP2C8",
            "DUSP6",
            "MB",
            "COX8C",
            "ZNF667",
            "FUNDC2P2",
            "TC2N",
            "OSR2",
            "LOC284661",
            "UGT2B15",
            "MAEA",
            "HIST1H3H",
            "GPR88",
            "STK32C",
            "OR52B4",
            "FGF4",
            "TTLL8",
            "TSPYL6",
            "C7orf28B",
            "LRRC10B",
            "MSLNL",
            "OR5AK2",
            "IFNA8",
            "ZNF584",
            "GHSR",
            "VHLL",
            "DPRX",
            "NKX2-2",
            "LEMD1",
            "MAGEB16",
            "HMX1",
            "C1orf230",
            "ZNF521",
            "PHYHIP",
            "C14orf19",
            "CCDC157",
            "C6orf191",
            "LOC255025",
            "FAM138D",
            "LACRT",
            "OR5B12",
            "PABPN1L",
            "FGF16",
            "OR4F29",
            "DCX",
            "LOC100132831",
            "RBMY1A3P",
            "SNORA51",
            "CDX2",
            "FRMPD4",
            "IL1F6",
            "KY",
            "TRIML1",
            "NKX3-1",
            "F2RL2",
            "CLDN25",
            "GALC",
            "TPH2",
            "PATE3",
            "PROKR1",
            "HIGD2B",
            "LOC642597",
            "PSD2",
            "CABP4",
            "PNLIP",
            "SLC9A10",
            "WDR66",
            "GAD2",
            "TRH",
            "SERPINA9",
            "ROBO1",
            "GDF5",
            "PRAMEF4",
            "FAM21B",
            "SPATS1",
            "DNAH2",
            "LRRC4",
            "RHD",
            "KCNMB3",
            "LOC400804",
            "SIGLEC12",
            "CC2D1B",
            "FAM187B",
            "ACP6",
            "FAM135B",
            "?|100130426",
            "C6orf58",
            "NRAP",
            "ACTRT1",
            "SLC7A3",
            "SNAR-H",
            "SNORD90",
            "KRTAP21-1",
            "ACCN5",
            "TSSK2",
            "OR11H12",
            "SNORD88C",
            "LOC653545",
            "SLC39A10",
            "SPINK14",
            "KRTAP22-1",
            "NMS",
            "SNORA11C",
            "TTTY3B",
            "SNORD16",
            "SNORD116-19",
            "DEFB114",
            "TTTY22",
            "TTTY17B",
            "SNAR-D",
            "DEFB113",
            "SNORA30"
        ],
        "Coefficient": [
            6.7007176999500615,
            -5.845973236090817,
            3.65423133639158,
            -3.1977208922913336,
            -2.9137421349945636,
            -2.894924064389452,
            2.8607194781917906,
            -2.827849430994763,
            2.7913355823989656,
            2.727384761632039,
            -2.727144316569551,
            2.643363828348921,
            2.6299692929305203,
            2.605861591456312,
            2.5419725933529893,
            -2.5192004940542554,
            2.4311859294386466,
            -2.403036121753924,
            2.402406713192308,
            -2.394144016598196,
            -2.321152069222864,
            2.3108723444278487,
            2.261077158986519,
            -2.23660164727147,
            2.2330555531623637,
            -2.2173767610773534,
            2.201590518002648,
            2.179373815691102,
            2.066273836385597,
            2.046568142790361,
            -2.0357097620222335,
            2.0156558942090155,
            1.980289490713942,
            -1.9417840392916497,
            -1.9156664762978375,
            -1.9081130755726528,
            1.9055923224571818,
            -1.8862544889740485,
            1.8512060854029622,
            1.8270890365137493,
            -1.822552347654316,
            -1.8134202925912708,
            1.8072792508493503,
            1.800024830729644,
            1.795630347147056,
            -1.7784181530403687,
            1.7541256687608409,
            1.7390264221314091,
            -1.7079681761352048,
            1.7045399354478938,
            -1.681005830945319,
            1.6800125282977505,
            -1.6754612508995448,
            -1.6671991557274681,
            1.6329775785592315,
            -1.6175381988256996,
            1.6016767903569307,
            1.5919995374230191,
            1.571245066462306,
            1.5690231908102665,
            1.5429216400179309,
            -1.5128993158043684,
            1.491053052526309,
            1.4893743625591522,
            1.4860715431007057,
            -1.4843892253203013,
            1.478042239971766,
            -1.4368489621643534,
            -1.434336350625586,
            1.4222060743363008,
            -1.4098441650759188,
            -1.3880806332712554,
            -1.370057806565775,
            1.3617606500599717,
            -1.3422781990007342,
            -1.3164182246736875,
            -1.3043558289843846,
            1.3025496707065165,
            -1.2979393147496472,
            -1.2936412009610245,
            1.271681009233158,
            -1.2631340997162188,
            -1.2620931031469815,
            1.2582991200198839,
            -1.2562631550871872,
            -1.2531673536778105,
            -1.248997969126761,
            -1.2485277193410207,
            -1.2400635521182704,
            1.2390188649319718,
            -1.2358097472641574,
            -1.231614083231795,
            1.2256496466514957,
            1.224943631929704,
            -1.2148662369111305,
            -1.2146723998066653,
            1.1998150130623604,
            1.1920330329084143,
            1.1860106783326958,
            1.1844622252579131,
            -1.1818993293389555,
            1.1808721373070425,
            1.1747808110728606,
            -1.1726413967876874,
            -1.1704346752920325,
            1.1589487759423789,
            1.1525640429900315,
            -1.1468919672166529,
            1.1407183260501634,
            1.1305916952705102,
            1.1290790323007482,
            1.1279084842805256,
            -1.1235081074576572,
            1.1031783275155957,
            -1.0996225476711805,
            1.0916934356406658,
            1.0887150407369044,
            -1.087485793102862,
            -1.0767790399904464,
            -1.0582941104214678,
            -1.057536539032447,
            1.0574559120141294,
            1.0503346699163822,
            -1.0364473673017043,
            -1.0342331837790335,
            -1.0235162344691344,
            -1.0174719848078568,
            -1.0108174474978546,
            -1.0071246389442872,
            -1.0047352950587138,
            0.9895584892282566,
            0.9866146187628531,
            0.9829420225151143,
            0.9816709898329844,
            -0.9749840162481057,
            0.9685540355596485,
            0.9646934003971938,
            0.9524734815959403,
            -0.9468183211779595,
            -0.938781936623672,
            -0.9337323391084134,
            0.9289134386072888,
            0.9286091549247278,
            0.9213023289540162,
            0.9120765599063706,
            -0.9099300773364027,
            0.9052474218593686,
            -0.9038622404314715,
            0.9006766627022422,
            0.898475710127322,
            0.8981952365679181,
            0.8962271279178775,
            -0.8892377309882273,
            0.8854580687412533,
            0.8762551550471912,
            0.8701602974828728,
            -0.8606906289401249,
            0.8567903108299658,
            -0.8522137946504248,
            -0.8486241005681066,
            -0.8416821590065893,
            0.8396040833297224,
            -0.8375165479892616,
            0.8357349634925081,
            -0.8277282000369123,
            -0.8272579034533216,
            0.8196191066347399,
            -0.8142062747382878,
            0.81366829704025,
            0.8128119032835999,
            0.8113035300788628,
            0.8096816220212424,
            0.8063462221397215,
            0.804700026138439,
            -0.8016220687857857,
            -0.8016214891172811,
            -0.7967842640130289,
            -0.7909887097723584,
            0.7909352366346722,
            -0.7862886127054801,
            -0.7843051193467082,
            0.7773237193836876,
            0.773930951882877,
            -0.7694167087831422,
            0.7637706229006181,
            0.7622790278456001,
            0.7621922829190066,
            0.7599528674803089,
            0.7586160222392146,
            0.7582002143549809,
            -0.7547823854831607,
            -0.7448776970438242,
            0.7448098311566619,
            -0.7388685837791442,
            0.7379501296141261,
            0.737672829429563,
            -0.7331137473101615,
            -0.732510481792702,
            0.7309705992853734,
            -0.7298614007939157,
            0.7258697178216728,
            -0.7240196160518534,
            -0.7239673310417744,
            0.7220393485468968,
            -0.7215581772429148,
            -0.7208357674270521,
            0.720805953487385,
            -0.7160947882588987,
            -0.7137617637234349,
            0.7115635367631523,
            0.7103622389865082,
            -0.7082401899087304,
            0.7076494517935764,
            0.7033014135680631,
            0.7013740249590327,
            0.7008517506172207,
            0.6972727355885839,
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