{
    "significant_genes": {
        "Variable": [
            "CT47A11",
            "SLPI",
            "CALML5",
            "PSMB1",
            "OR51M1",
            "TRRAP",
            "MYH2",
            "TRIM51",
            "LHFPL3",
            "TMEM114",
            "SPDYE6",
            "SNAR-C4",
            "NAAA",
            "EEF1AKMT3",
            "IER3",
            "FBXO10",
            "ARHGAP44",
            "TBC1D21",
            "SPATA31J1",
            "AIRE",
            "SEC1P",
            "DUSP5P1",
            "AADACL4",
            "CDK11A",
            "ZNF718",
            "UNCX",
            "RAB9BP1",
            "MSL1",
            "APOL4",
            "LOC389705",
            "SMCO1",
            "PCDHA4",
            "RBMY1A3P",
            "CLDN16",
            "PRM2",
            "SEC31A",
            "KRT86",
            "GNPDA2",
            "MCUB",
            "ERICH6B",
            "MED9",
            "SLC38A7",
            "REN",
            "OR2C3",
            "IFNW1",
            "RBMY3AP",
            "IL3",
            "CASTOR2",
            "B4GALNT2",
            "CLTA",
            "RPL36A",
            "C6orf58",
            "SAMM50",
            "H4C11",
            "ACP4",
            "ZNF330",
            "SNORA65",
            "MORN1",
            "SNORA79",
            "PPBP",
            "TAAR9",
            "ABCA2",
            "CD207",
            "RPL13AP3",
            "POU4F3",
            "TNK2",
            "CENPW",
            "GMPR2",
            "FAM25G",
            "CBARP",
            "FAM66C",
            "ABTB3",
            "GDNF",
            "SNORA3A",
            "PITX2",
            "DDTL",
            "VWA3A",
            "KRT25",
            "NUDT9",
            "CITED4",
            "NTN5",
            "IL23R",
            "FAM227B",
            "TKTL2",
            "PIGR",
            "ZNF30",
            "DNAJC19",
            "CES5A",
            "IL17A",
            "COLEC11",
            "QPCT",
            "KRT81",
            "LCN6",
            "KRT38",
            "ZPBP",
            "HCAR2",
            "CLEC12B",
            "ZC2HC1C",
            "MYBPH",
            "GARIN5A",
            "ROBO3",
            "CBY2",
            "FOXG1",
            "TXNL4B",
            "NEK10",
            "PLA2G5",
            "MGC27382",
            "LGR6",
            "OR13A1",
            "ZNF558",
            "GDPD1",
            "PAX8",
            "TLCD4",
            "OR14A16",
            "CDKN2AIP",
            "WFDC9",
            "HOXA5",
            "PABPC1L2A",
            "GCDH",
            "TTTY3B",
            "LHX9",
            "SETD3",
            "DUSP4",
            "C9orf72",
            "NKX6-1",
            "MFSD2A",
            "CHIT1",
            "CDK8",
            "TNFSF18",
            "VAPA",
            "ALKAL2",
            "ALDH4A1",
            "DNAAF6",
            "S100Z",
            "HDHD2",
            "CHCHD5",
            "PEG3-AS1",
            "CYP11B1",
            "ZNF479",
            "LSM6",
            "PRG3",
            "FREY1",
            "EEF2KMT",
            "SPATA22",
            "CX3CR1",
            "FAM151B",
            "SYS1-DBNDD2",
            "SNORD103A",
            "AGAP5",
            "ERVFRD-1",
            "NMBR",
            "RAG1",
            "MUCL1",
            "ADAM29",
            "NRN1L",
            "BDH1",
            "IL36G",
            "VKORC1L1",
            "CIMAP1C",
            "C3orf38",
            "TATDN2",
            "LINC01600",
            "NT5C3B",
            "PKDREJ",
            "DMC1",
            "SLC14A1",
            "IRF8",
            "HS6ST2",
            "PEX3",
            "ZNF85",
            "ARSH",
            "BTG1",
            "DCDC2",
            "PRB2",
            "EPHB6",
            "RFPL3",
            "AMER3",
            "CLLU1",
            "C11orf16",
            "ATG10",
            "KRTAP4-11",
            "VAX2",
            "CACNA2D3",
            "HGFAC",
            "IL1RAPL1",
            "INTS11",
            "LINC01555",
            "LENG9",
            "CPA1",
            "LCNL1",
            "AKR1C8",
            "C17orf99",
            "FAM163A",
            "GSTM1",
            "TRMT61B",
            "ZNF28",
            "HLA-J",
            "TMEM143",
            "FBXO36",
            "KRT37",
            "BPI",
            "BARHL1",
            "AKAP4",
            "LPCAT2",
            "FGF7P6",
            "MB21D2",
            "SPP2",
            "EYA2",
            "NRN1",
            "RNF220",
            "DLL3",
            "SNORA66",
            "CEP128",
            "OVCH1",
            "PKP2",
            "CATSPER4",
            "ELP2",
            "POM121L10P",
            "OR2T35",
            "RUFY2",
            "SCGB2B2",
            "FAM169BP",
            "OR4C15",
            "PSMB4",
            "PMS2CL",
            "ECHDC3",
            "RRP7A",
            "PMCH",
            "CHRNA1",
            "ZPLD1",
            "LOC730668",
            "ZNF468",
            "STBD1",
            "CHD1L",
            "KCNK2",
            "CHRNA9",
            "TREML5P",
            "MMAA",
            "CCDC160",
            "OR5AS1",
            "ERC2-IT1",
            "PPP1R27",
            "PPEF1",
            "PLSCR5",
            "METTL2B",
            "SAA2",
            "DNAH14",
            "LCE4A",
            "ARG1",
            "SDHAP3",
            "DEFB112",
            "BHLHE23",
            "IGFBP1",
            "PATE2",
            "YWHAG",
            "CA4",
            "PSORS1C1",
            "RASA4CP",
            "RTL4",
            "DHRS2",
            "SPDYE8",
            "DNAJC25-GNG10",
            "TRMT1",
            "CXorf65",
            "CCL18",
            "SPINK6",
            "ZNF14",
            "FGF16",
            "TRIM44",
            "AQP5",
            "ATP6V1G3",
            "MBL2",
            "NXF3",
            "OR2A2",
            "SNORD12B",
            "CRISP2",
            "LINC00652",
            "INSYN2A",
            "DAZ4",
            "SUGT1P1",
            "STEAP4",
            "C2orf81",
            "ZNF253",
            "GATA2",
            "RRN3P2",
            "CDK6",
            "VPS4A",
            "ATG4B",
            "MYL2",
            "FECH",
            "HMG20B",
            "RIPK1",
            "TSNAX-DISC1",
            "SNORA2B",
            "MTMR9",
            "ELOA2",
            "PDZK1P1",
            "UBE2U",
            "ANKK1",
            "CFAP210",
            "OOEP",
            "FIGNL1",
            "ZNF833P",
            "GNG8",
            "MFGE8",
            "FAM238A",
            "UGT1A9",
            "CATSPERZ",
            "SENP8",
            "CLC",
            "RGS8",
            "FBXO24",
            "C17orf50",
            "PAQR9",
            "SNORA31",
            "SCARNA14",
            "EGLN1",
            "GAPDHS",
            "FLT3",
            "PIH1D2",
            "PLAC1",
            "CXCL2",
            "H2BC10",
            "DHRS7B",
            "PLIN1",
            "TCAM1P",
            "FOXI3",
            "GGT6",
            "SEPTIN9",
            "PARM1",
            "TTTY4C",
            "DACH2",
            "LOC283731",
            "GSTA5",
            "LINC00261",
            "RASAL1",
            "TCFL5",
            "WHR1",
            "BSX",
            "GRM8",
            "AWAT2",
            "PEX1",
            "SCOC",
            "KRTAP10-10",
            "MRPL42P5",
            "KRT12",
            "SNAR-H",
            "TUBB2A",
            "TRIM63",
            "DAP3",
            "TRH",
            "MEPE",
            "COG7",
            "TRPM2",
            "NPAP1",
            "SSX2",
            "NKX6-2",
            "CCDC77",
            "RCC1L",
            "RNASEH1",
            "PRKD3",
            "CFAP91",
            "TP63",
            "LINC02693",
            "UBAP2",
            "HTR3B",
            "RPS6KA5",
            "PRPF8",
            "NPRL3",
            "VRTN",
            "CYP4A11",
            "ZSCAN5B",
            "DNAH17",
            "TDRD1",
            "DMRTC1",
            "HBBP1",
            "WNT3A",
            "FAM201A",
            "RETREG1",
            "CGB1",
            "KLK10",
            "FAM27E5",
            "LINC03042",
            "PXYLP1",
            "KRTAP4-4",
            "GPS1",
            "SNORA59B",
            "SNORA29",
            "INSRR",
            "GYPB",
            "CA12",
            "ARRDC4",
            "PIGQ",
            "SENP1",
            "C4orf51",
            "H2AC21",
            "TTTY13",
            "SLFN13",
            "CETN4P",
            "HTR2B",
            "HAUS4",
            "BLID",
            "OR52D1",
            "AGPAT3",
            "RHOXF1",
            "SOX3",
            "OR12D2",
            "ARR3",
            "GDI2",
            "SLC5A8",
            "TYRO3",
            "PSMC3",
            "OR4M2",
            "HBQ1",
            "HTR1B",
            "UTS2B",
            "LRRC27",
            "PCDH11Y",
            "SPACA5",
            "FAM185A",
            "MED12L",
            "SDCCAG8",
            "SERPINB9",
            "INTS4P1",
            "PDE6C",
            "NUTM2A",
            "PRSS57",
            "PTPN18",
            "SMN2",
            "COPG2",
            "ZNF165",
            "PGM5P2",
            "SFTPB",
            "PCNAP1",
            "GNAT3",
            "HAUS7",
            "STARD6",
            "FOXL2",
            "SLC7A3",
            "CTRB2",
            "SLC25A37",
            "TMEM229A",
            "SCGB1D1",
            "H4C7",
            "SNORD97",
            "LOC145474",
            "XAGE5",
            "SCARNA15",
            "TNIK",
            "PRM3",
            "CYP19A1",
            "RPS4Y2",
            "TRARG1",
            "FBXW5",
            "IAPP",
            "MYL1",
            "DPYSL5",
            "NPDC1",
            "MIOX",
            "MSH4",
            "KLHDC8A",
            "AANAT",
            "PNLIP",
            "GPR37L1",
            "ZNF792",
            "ABCC12",
            "GUSBP1",
            "DEFB106A",
            "OR2T33",
            "TBR1",
            "ELP4",
            "RPL23AP7",
            "SAA1",
            "WDR86",
            "USP54",
            "HES6",
            "RP1",
            "HAPLN2",
            "POLD3",
            "GKN2",
            "LRRC37A2",
            "NPFFR2",
            "ZACN",
            "MTARC1",
            "SALL1",
            "DCC",
            "GARIN1A",
            "ZNF613",
            "ZNF556",
            "FLCN",
            "PRLHR",
            "ACVR1C",
            "CLEC4F",
            "SLC13A1",
            "ATP13A5",
            "CMA1",
            "TRPM3",
            "RNF138",
            "ADAMTS16",
            "WDR59",
            "SPRY2",
            "KDM4E",
            "POU3F2",
            "CYMP",
            "DCAF12L1",
            "C22orf15",
            "LITAF",
            "KISS1",
            "GTPBP1",
            "ZIC1",
            "PRR20B",
            "SNORA49",
            "GSTM2P1",
            "HAR1B",
            "MIMT1",
            "SLC5A10",
            "LIMS3-LOC440895",
            "H1-1",
            "TPSG1",
            "ST7L",
            "TNNI3K",
            "TMEM26",
            "FHAD1",
            "NOS1AP",
            "ITFG2",
            "H3C12",
            "ASPG",
            "LUC7L2",
            "OR2L1P",
            "RTCB",
            "CATSPERD",
            "FBXO48",
            "SNAR-I",
            "RNASE1",
            "ARMCX5-GPRASP2",
            "MEG8",
            "OR1J2",
            "KRTAP19-2",
            "SLC44A1",
            "FAM47C",
            "GAGE13",
            "C11orf40",
            "CPB1",
            "FAM136BP",
            "TRMT9B",
            "CALHM4",
            "CPN2",
            "SLC10A7",
            "LINC00515",
            "RBMY1B",
            "PRAC1",
            "DSC1",
            "GUSBP3",
            "SNAR-A13",
            "SNORD115-20",
            "CDKL3",
            "TULP3",
            "RPH3A",
            "OR2T29",
            "GIPR",
            "KCNJ1",
            "PPIL6",
            "ART3",
            "TTC16",
            "NUP210L",
            "GNRH2",
            "DLK1",
            "TSSK2",
            "GATA6",
            "CACNA1A",
            "PRR20C",
            "SNAR-B2",
            "PRR20D",
            "SNAR-C2",
            "SNAR-C3"
        ],
        "Coefficient": [
            -3.9926982025433677,
            -2.3353354718251786,
            2.313063312608099,
            -2.306260914007373,
            -2.2805339640094053,
            -2.1180532574009017,
            -2.053887214865043,
            2.043622967100382,
            2.0277447247175466,
            2.0127463845883495,
            -1.9464626853070341,
            1.9101459695530842,
            -1.8497678113501181,
            -1.7764740322110029,
            1.7744147778803314,
            1.7467808191102272,
            -1.6464514370010745,
            -1.6061393599976104,
            1.5837126212384263,
            1.565504009737656,
            1.5527241671020624,
            1.545931659933116,
            -1.516858855169306,
            1.5063279940074756,
            1.4351478385059993,
            1.4318061310077776,
            -1.405247331887371,
            -1.4036243884324096,
            1.3962171210254475,
            1.388038141861341,
            -1.3813425341876793,
            -1.3594860691285717,
            -1.3450031649699967,
            1.329005007490616,
            -1.2825926477187777,
            -1.2815457345822179,
            -1.2251446948909173,
            -1.2200459278050773,
            -1.2133353791982853,
            -1.2060281659949503,
            1.2019865422129103,
            1.1937512663926368,
            1.1912965664861581,
            1.1910332438218818,
            -1.1901189654833269,
            -1.186290924097409,
            1.1724772670429715,
            -1.1627606777035495,
            1.1416962248396352,
            1.1398546945797814,
            -1.1345535716847204,
            -1.134005543996045,
            -1.1334596256504699,
            -1.1229807547401505,
            -1.1188985572908325,
            -1.1036243296005739,
            -1.101780980111405,
            1.099515558182064,
            1.0989644548459072,
            1.0940957800747433,
            1.0929424295429315,
            -1.0863253130369321,
            1.0821634215266083,
            1.0689088659009893,
            1.066934924298737,
            1.0666869394647445,
            -1.0649487921277858,
            -1.0641030968389475,
            -1.0610176455472873,
            1.0539127923113285,
            -1.0489188995724121,
            -1.0470516465729356,
            -1.0403811797762204,
            1.0351182851492,
            -1.0237565251444287,
            1.0204435917007966,
            1.0167706139020314,
            -0.9843042200890064,
            -0.9692832311955629,
            0.9670221848413424,
            0.9573371082452444,
            -0.9568247508306905,
            -0.9505994818795003,
            -0.9499882781807362,
            -0.9468191114721413,
            -0.9386346532527977,
            0.9358304892239774,
            -0.9326529241816305,
            -0.9325337111944423,
            0.9136543444926868,
            0.9063309978883298,
            -0.9051540501765238,
            -0.8880090224769608,
            -0.8849472774032145,
            0.8788605140432489,
            -0.8753342547094084,
            0.8632353332104538,
            0.8578787420728613,
            -0.8461317667624837,
            0.8448656755303062,
            -0.8370358760187167,
            0.8357730026828082,
            -0.8349162282880828,
            -0.8217451341718678,
            0.8149645507323315,
            -0.814640603530156,
            0.8098954414210007,
            0.8023056443858402,
            0.8005964149014994,
            0.793295851676156,
            0.7880516463475827,
            -0.7828304679082176,
            -0.7815321543272646,
            0.7801755050002022,
            0.7794565298046088,
            -0.7789182464137644,
            0.7789127837026079,
            -0.7771289665723261,
            -0.7714110876888668,
            0.7713392876413478,
            0.7674043654686434,
            -0.7574728599221356,
            0.7495864834006609,
            0.7383042617371208,
            -0.7344717300145395,
            0.73050610758578,
            -0.721956070983572,
            -0.7208657823236957,
            -0.7179950183768566,
            -0.7177194194056885,
            -0.7162631035978893,
            0.7028470180327538,
            -0.693613912766408,
            0.6862911474580069,
            0.6836194442724446,
            -0.6823267311116192,
            -0.6811153942402989,
            -0.6801709630026044,
            0.6696269570086152,
            -0.6658361783086364,
            0.66505030450593,
            0.6648840332075557,
            -0.6647026988958459,
            -0.6588477830573543,
            0.6585724976998847,
            -0.6556205623094609,
            0.6478353832889318,
            -0.6459901301121205,
            0.6418819468049439,
            0.6413098997579834,
            0.6364500337649587,
            -0.630176211704829,
            0.6297463119371446,
            0.6284898550146386,
            -0.6233112477628557,
            0.6224537203669804,
            0.6217569343961606,
            -0.6155189991332705,
            0.6146265129844732,
            0.6133226189874096,
            -0.6111410030032395,
            -0.6091566343393825,
            -0.607966820193142,
            -0.6060736134018199,
            -0.5973694596793423,
            0.593979636261897,
            0.5928100759129126,
            0.5926506182730535,
            0.5762144790064692,
            0.5748149241602432,
            0.5740913216864378,
            -0.5717933698328175,
            0.5706481415201543,
            -0.5654431889865357,
            0.5635284565151966,
            -0.5569341540803099,
            -0.5550557118934695,
            0.5541826888528119,
            0.549074170412113,
            -0.5478539654178146,
            -0.5449551042170585,
            0.5434154381976201,
            0.5416131724870815,
            0.5393942289168093,
            0.5392101403850711,
            0.5386933425175464,
            0.5386038510569868,
            -0.5374282158855627,
            -0.5365440497775545,
            -0.5362835761175464,
            0.5344113421498644,
            0.5324624831135386,
            0.51156316758452,
            0.506805459591755,
            0.5062797222982708,
            0.5058867196371292,
            -0.5042492214061974,
            -0.5036923154897552,
            0.4988952261670526,
            -0.49834726357824216,
            -0.49438831467779176,
            -0.4929633758779741,
            0.49148034359355747,
            -0.4906125331160978,
            -0.482000686734102,
            0.4765632679142233,
            -0.47522578464986415,
            -0.4712925204137184,
            0.4680269759003452,
            -0.456628379914062,
            0.454477739415476,
            0.45294991769699244,
            -0.44783494429301285,
            0.4449187576312733,
            0.44357372026489855,
            -0.4375832550844725,
            0.436600120879951,
            0.42871871162683917,
            0.4235013566594171,
            0.4226488521413227,
            -0.41896055733058957,
            0.4168837034359027,
            0.41249891571106173,
            -0.4121857201009705,
            0.4119530307929319,
            0.40954523032235646,
            -0.4093039661330469,
            -0.4074549007435866,
            -0.40127813682117025,
            0.3991452277526074,
            -0.398311374481298,
            0.3961612409378975,
            -0.3948972304678265,
            -0.391879520006142,
            0.3915407163687576,
            0.3915045165279991,
            0.39122581207796686,
            -0.3901229378520489,
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