{
    "significant_genes": {
        "Variable": [
            "CT47A1",
            "COX7A2L",
            "ZNF410",
            "ZFAND3",
            "OOSP2",
            "MMP7",
            "SBDSP1",
            "AASS",
            "ARL11",
            "UNC119B",
            "LRIT1",
            "OR1Q1",
            "HYKK",
            "PLAGL1",
            "TSPY1",
            "CHRNB1",
            "NETO1",
            "OR51L1",
            "SPANXA2",
            "NPAP1",
            "A4GNT",
            "GOLGA8DP",
            "TAF15",
            "ZNF878",
            "HTN3",
            "LCE1C",
            "MAGEA12",
            "FKSG29",
            "CFHR4",
            "TCERG1L",
            "H1-9P",
            "HYAL6P",
            "LNP1",
            "COLEC11",
            "SLCO6A1",
            "HBE1",
            "CPLX4",
            "PTENP1",
            "ZNF578",
            "RPH3AL",
            "MERTK",
            "GLRX2",
            "GTPBP10",
            "PRSS45P",
            "H2AC1",
            "LAIR2",
            "GLT1D1",
            "TBPL1",
            "SAFB",
            "TRIM41",
            "NIBAN2",
            "FERD3L",
            "KLHDC8A",
            "HOXC11",
            "OR7D2",
            "GLRA2",
            "RBMXL3",
            "NSG2",
            "EFCAB6",
            "PRAMEF4",
            "POU3F2",
            "SLC25A51",
            "LIPI",
            "LINC00518",
            "C4orf50",
            "SART3",
            "DLGAP1",
            "TSPAN10",
            "OR1L8",
            "PRSS33",
            "SNORA32",
            "PELO",
            "H3C6",
            "CNPY1",
            "OR2B11",
            "HEMGN",
            "PRKRA",
            "FAM227B",
            "PMS2P5",
            "HAO2",
            "C10orf62",
            "SCGB3A2",
            "HSP90AB1",
            "HCN1",
            "OR5J2",
            "SPAG11A",
            "LOC284009",
            "RBM44",
            "HCG26",
            "CD300LD",
            "SNORA70B",
            "HK2",
            "OPN4",
            "C17orf78",
            "TTC36",
            "LCE6A",
            "GABRR3",
            "SLC39A12",
            "SSX7",
            "ANGPTL7",
            "IL2",
            "DQX1",
            "PTPRT",
            "HIGD2B",
            "FBLN7",
            "GSTT4",
            "OR52K2",
            "LY6K",
            "GRAPL",
            "PPP1R3B",
            "LELP1",
            "GPR151",
            "GLYATL3",
            "H3C4",
            "SLC10A2",
            "SLC35B2",
            "ALPP",
            "TCHHL1",
            "SLC30A3",
            "SPAG6",
            "ATXN3L",
            "CTAG2",
            "PEBP4",
            "RXFP1",
            "SREK1IP1",
            "TERB1",
            "BOLA1",
            "CELA1",
            "IFNA4",
            "TRIM51",
            "RBM23",
            "PRDM14",
            "OR13F1",
            "FAM181A",
            "PLAGL2",
            "GTF2IP1",
            "UMOD",
            "GTSE1-DT",
            "PAPSS1",
            "KIF2B",
            "TXNIP",
            "KRTAP13-2",
            "TBC1D29P",
            "SERPINB10",
            "TMPRSS11A",
            "PPP2R2C",
            "KRTAP7-1",
            "FGF7P6",
            "ZNF90",
            "SBK2",
            "KCNH8",
            "H1-6",
            "CCDC74A",
            "PIGC",
            "IFNL1",
            "ROS1",
            "ZAR1",
            "OR51F1",
            "PABPC1P2",
            "CEP43",
            "PRG1",
            "OR2J2",
            "ALX1",
            "GPATCH1",
            "F8A1",
            "CRLF2",
            "USP17L6P",
            "CDH6",
            "COPS3",
            "CLHC1",
            "SYNGR4",
            "OR10G4",
            "KRTAP10-9",
            "LINC00471",
            "SERPINE3",
            "DAD1P1",
            "EHD1",
            "SYCP2",
            "CFAP74",
            "NEIL3",
            "OR5B3",
            "OR52A1",
            "IRGC",
            "C5AR2",
            "FAIM",
            "OR4F15",
            "TTTY8",
            "AVP",
            "FLG2",
            "CNGA2",
            "SLC28A2",
            "COMMD8",
            "METTL8",
            "SPATA8",
            "RIMBP3C",
            "SPP1",
            "HSF5",
            "H2BC1",
            "GPR82",
            "SNORA38B",
            "SLC2A11",
            "SPINK8",
            "LOC153910",
            "OR52M1",
            "SALL4",
            "GSTM1",
            "SPANXN2",
            "SDHAF3",
            "DGCR5",
            "SLC35G6",
            "TAAR8",
            "SND1",
            "GARIN5B",
            "PCDHGA3",
            "FRMD1",
            "FAM106A",
            "ZNF764",
            "ABCG8",
            "KLK8",
            "RETN",
            "SSX1",
            "ID4",
            "OTUD7B",
            "NEUROD2",
            "CSMD1",
            "SCARNA18",
            "TSPYL1",
            "SPANXB1",
            "GRIK2",
            "KRT37",
            "SLC6A18",
            "DPPA4",
            "SLC7A5",
            "TICAM2",
            "SLC7A5P1",
            "ANKRD40CL",
            "REDIC1",
            "PDHA2",
            "REG1B",
            "RPS28",
            "CCDC116",
            "HSD3B1",
            "NIPA2",
            "TMCO2",
            "TEX13B",
            "SLC35F3",
            "IQCF2",
            "P2RX5",
            "HCRT",
            "DEFB113",
            "SLC25A23",
            "ERP44",
            "INGX",
            "MYO3B",
            "GLT6D1",
            "IL21",
            "GJB6",
            "KRTAP5-11",
            "DIS3",
            "MSX2P1",
            "XRCC1",
            "ZNF334",
            "NUTM1",
            "PLET1",
            "AIPL1",
            "DEFB103B",
            "TCTN2",
            "FOXD4L3",
            "OR2T27",
            "OARD1",
            "KIAA0040",
            "RXFP2",
            "SOX3",
            "A1BG",
            "TCEAL6",
            "HTR2C",
            "GRXCR2",
            "NME5",
            "OR56A4",
            "RPL10",
            "H1-3",
            "HAUS2",
            "CRH",
            "LRRC4B",
            "SPRYD3",
            "ADCYAP1R1",
            "IL1RAPL1",
            "MIXL1",
            "LRIT2",
            "SHH",
            "KRT76",
            "OR6N2",
            "OR51F2",
            "CCNE1",
            "OR10P1",
            "NBR2",
            "FLVCR2",
            "FAM181A-AS1",
            "PMCH",
            "KCNK18",
            "ADO",
            "GGT8P",
            "TASP1",
            "ZSCAN2",
            "PAGE2B",
            "RPL9",
            "RAX",
            "PLXNB2",
            "GRIA4",
            "ETNPPL",
            "POLR2J2",
            "TLCD3B",
            "EFHD1",
            "SESN1",
            "ATP4A",
            "APEX2",
            "MUC7",
            "TRAK1",
            "PP2D1",
            "PKIB",
            "IFNK",
            "RNF135",
            "SLC5A12",
            "NPFFR1",
            "UGT3A2",
            "PPP1R2C",
            "ZMYND12",
            "TPD52L1",
            "TUB",
            "GLIPR1L2",
            "ATXN7L3",
            "OR2T12",
            "LEMD1",
            "MICA",
            "CHKA",
            "KRT35",
            "TFAMP1",
            "OR2T10",
            "RPS26P11",
            "RRH",
            "TENT5D",
            "ADAM20",
            "PGPEP1",
            "ARRDC4",
            "ARMT1",
            "GTF2A1L",
            "NFIB",
            "IFNA16",
            "LOC646813",
            "KRTAP4-1",
            "KRT33A",
            "TRAPPC3L",
            "CASP12",
            "TUBB8",
            "WRNIP1",
            "DIRC1",
            "NUDT9P1",
            "NXPE2",
            "H3C7",
            "OR1B1",
            "WEE2",
            "GBE1",
            "PRL",
            "MIR9-1HG",
            "ADGRA1",
            "H4C3",
            "IFNA7",
            "NYAP2",
            "MAPK10",
            "TREML4",
            "CCDC70",
            "HPYR1",
            "GPR32",
            "GOLGA8IP",
            "SP7",
            "NAA50",
            "DNAAF4",
            "TAS2R30",
            "CHRNA9",
            "CYP8B1",
            "IL12RB2",
            "MCM9",
            "NTPCR",
            "ABCA7",
            "SLC35E2B",
            "PPP1R1C",
            "C20orf141",
            "BEND2",
            "MINDY4",
            "SPMIP2",
            "GPR78",
            "CACNB3",
            "NKAIN2",
            "SYN3",
            "CCL15",
            "SIX3",
            "MCM3",
            "SLC6A3",
            "MAGEB1",
            "GUCY1B2",
            "SLC66A1LP",
            "HMGN3",
            "PPP1R21",
            "LINC00158",
            "PNPLA3",
            "RABL2A",
            "GSTT2",
            "WDR64",
            "SLC22A6",
            "KHDRBS2",
            "GUCY2EP",
            "OLAH",
            "DCDC1",
            "HLA-DQA1",
            "FAM170A",
            "GABRB1",
            "FRG1BP",
            "FNTB",
            "ZNF326",
            "IQCD",
            "OR2M3",
            "S100A5",
            "SLC4A10",
            "SOHLH1",
            "HNRNPUL2",
            "PSORS1C1",
            "RAET1L",
            "LINC00200",
            "LOC100192426",
            "GATA4",
            "TOB1",
            "ZFAND2A",
            "FBXO43",
            "SCGB1C1",
            "HIVEP2",
            "UCP1",
            "OR2AK2",
            "CEACAM8",
            "OR51A4",
            "SKINT1L",
            "OR10T2",
            "IGFL2",
            "KLKB1",
            "SPATA31E1",
            "TBCC",
            "PDYN",
            "FAM180A",
            "LRRC10",
            "CYP4F11",
            "H4C6",
            "BAGE",
            "FAM25G",
            "DHH",
            "CDK11A",
            "TDH",
            "ZNF497",
            "THUMPD1",
            "IL36B",
            "OR52E6",
            "ERC2-IT1",
            "SAGE1",
            "OR2T11",
            "TACR1",
            "TRPV5",
            "NPLOC4",
            "NAP1L6P",
            "RLN3",
            "SPATA45",
            "NOTO",
            "DEFB136",
            "CETN1",
            "ZFAT-AS1",
            "ZUP1",
            "LIPH",
            "KRTAP9-2",
            "CEP170P1",
            "ZCRB1",
            "CST5",
            "TPM4",
            "GRIPAP1",
            "FBXO33",
            "C2orf78",
            "TMEM215",
            "LRP2",
            "OR51B5",
            "ECHDC1",
            "SNORA68",
            "APOL4",
            "HEXA-AS1",
            "LINC00589",
            "OR5F1",
            "BAALC-AS2",
            "RNF186",
            "PRSS3",
            "PGLYRP1",
            "ZNF17",
            "SAP30",
            "RFPL4A",
            "OR5D16",
            "TBC1D3P2",
            "TGM2",
            "NUFIP1",
            "SCARNA10",
            "SSTR5",
            "SNORD8",
            "VSTM1",
            "ANKRD34C",
            "NCR2",
            "HSD11B2",
            "OR1K1",
            "KRTAP19-2",
            "OR5B17",
            "ADAMTS20",
            "C11orf42",
            "SEC16B",
            "OR2F1",
            "OR5K4",
            "RWDD2B",
            "RBMY1B",
            "DEFB106A",
            "RBPJL",
            "PRR20A",
            "CFAP206",
            "GAGE2E",
            "KRTAP20-3",
            "TSSK2",
            "TREML5P",
            "SNAR-A13",
            "OR5H15",
            "BID",
            "FAM27E5",
            "EQTN",
            "CPO",
            "LCE2D",
            "SPACA7",
            "TTTY17A",
            "SNORD103A",
            "SNORD88C",
            "KRTAP22-1",
            "SNORD115-20",
            "LCE3B",
            "KRTAP19-4",
            "PRR20B",
            "RBMY1F",
            "TTTY17B",
            "SNORD116-19",
            "SNORD11B",
            "SNAR-H",
            "SNAR-A3",
            "SNAR-C3",
            "SNAR-G2",
            "SNORD16"
        ],
        "Coefficient": [
            -5.382157792116981,
            3.9865884837003325,
            -3.347343240895014,
            2.3137671682944942,
            -2.2932175808348716,
            2.240524225840999,
            -2.1839190050320214,
            -2.1281590508456123,
            2.0972953947584827,
            1.986258970422577,
            -1.9769593494095459,
            -1.9769162573582169,
            -1.9737412901496671,
            1.9636417866194504,
            1.9603820039888944,
            1.9549364859354204,
            -1.9390988995364618,
            1.93888226543538,
            -1.897923688524026,
            -1.8895073268466707,
            1.8445441888728649,
            1.8425428301982907,
            1.833706696005012,
            -1.7954520868324886,
            1.790379474832654,
            1.7186194409394389,
            1.7148977002013013,
            -1.704648017325542,
            1.701669571215836,
            1.66694834285103,
            1.6517494832295574,
            1.6399547305195248,
            1.6234206971869531,
            -1.615673223728751,
            -1.5449981381674827,
            1.525138541713987,
            1.5157970643270386,
            -1.5053054127334975,
            1.475736752953569,
            1.4678615202871852,
            1.46568244383376,
            1.45782288755334,
            -1.4457732227593814,
            -1.4027538916661277,
            1.3997117620030024,
            -1.3792113888183548,
            -1.3778853992967002,
            1.3654693751212519,
            1.347190498903421,
            1.3428339180489852,
            1.3409498630674528,
            -1.3361224329962904,
            -1.3331971640670015,
            1.3300763371049422,
            -1.3042385115498505,
            -1.3041653573230176,
            1.292620274520457,
            -1.2770843137691166,
            1.274132487599264,
            -1.2662433156407555,
            -1.2623041555646914,
            1.24773758344718,
            -1.24169030691328,
            1.2368333289244817,
            1.2323932792924224,
            1.2198046262020448,
            1.2181152004873543,
            1.217371745696084,
            -1.2073021801768278,
            -1.2037570358797745,
            -1.201073040343592,
            1.1930225418637532,
            1.1860361170681832,
            -1.1751309506702754,
            -1.1630986236994012,
            -1.1603005922206568,
            -1.157250121970792,
            1.1542976615070397,
            -1.150788654993696,
            -1.1410538879355931,
            -1.1370513448882826,
            1.1325575810567459,
            1.1165713919354998,
            -1.092691932459412,
            1.0898582165173258,
            1.0884710787759428,
            -1.0728037129207588,
            1.0722073411080013,
            1.0717325376088418,
            -1.0686023233593764,
            1.0568615814361373,
            -1.047787839816222,
            1.0466868561767975,
            1.043568429817304,
            1.04160137276795,
            1.039191012349473,
            -1.0376999094610218,
            1.0189531040735684,
            -1.0131359141776024,
            -1.0118763858815056,
            1.0096293722444725,
            -1.0089966359806484,
            1.0050915400353406,
            -0.9986743043955313,
            -0.9974431810957372,
            0.9912285229800094,
            0.9765975110544329,
            0.9763502528383553,
            0.971212963424984,
            -0.956978514745609,
            -0.9532152812880421,
            -0.9465889988425098,
            -0.9457903372039572,
            0.9420781644119443,
            -0.9343170543842151,
            0.9307094405953943,
            -0.9294887395615753,
            0.9261223155272551,
            -0.9222625803649889,
            0.9206037003795114,
            0.9187331466603527,
            0.9143877373872258,
            -0.8999825254453095,
            0.8987922632540802,
            -0.8929462446119858,
            -0.8913503174226338,
            0.8902179662327122,
            -0.8888161545065663,
            0.8866563151974124,
            -0.8843314138944632,
            0.8839477460391462,
            -0.8789324096827132,
            0.8760069002529635,
            -0.8743956570844896,
            -0.8712965569328168,
            -0.8675730258526784,
            0.867096156398043,
            0.8666374993185773,
            0.85877758371526,
            0.8539619344173287,
            0.851973239543873,
            -0.8462259350430966,
            0.8430568693219,
            -0.8360421778494922,
            0.828556797705251,
            -0.8237433349557138,
            -0.8160510909730012,
            -0.8076506677152788,
            -0.8037834997644487,
            0.7955856515976553,
            0.788629905236105,
            0.7826666878047361,
            0.773462574997618,
            0.7683571774601374,
            0.7679202118514463,
            0.7652433516640436,
            -0.7646507187099639,
            0.7614293675366312,
            0.7466876245214631,
            0.7466614686599489,
            0.7460375436915931,
            -0.7439373748758951,
            0.7420892137510793,
            -0.7383460322985936,
            0.7352687427475554,
            0.7299708454263809,
            0.7265961176356833,
            0.7221604165414798,
            -0.7210819214112816,
            -0.7129877677613885,
            0.7041094320051681,
            -0.7036974109400704,
            0.7031760217163624,
            -0.7026248467838814,
            0.7023090010196734,
            -0.7002201663926164,
            0.6984180167037038,
            -0.6955475644383498,
            0.6955468041260875,
            0.6927162455878171,
            0.6908758729849143,
            0.6888807032032368,
            -0.6847730267625751,
            -0.6833019822026304,
            0.681634875512139,
            -0.6777600696690602,
            0.6765283802221479,
            0.6753950031177357,
            0.6740434772651838,
            0.6687154045039232,
            0.668119128372153,
            0.6680084914122189,
            -0.6654275413522102,
            -0.6635577510334816,
            0.6601724473195696,
            -0.6589208571297477,
            0.6589022598549545,
            0.6568282048269323,
            0.655769495874295,
            0.6540340760925399,
            0.6474421606582514,
            -0.6474364932226422,
            -0.6452801851906041,
            0.6449720753864897,
            -0.6447950279742444,
            -0.6428389737433895,
            0.6422730337802167,
            0.6379974694443961,
            -0.6365482183437444,
            0.6311767220440951,
            0.6307307337711154,
            0.6306113504753104,
            -0.6223154074658352,
            -0.618128982142686,
            0.6161601159405212,
            0.6132711594250057,
            0.6120157519133202,
            -0.6109553155071041,
            -0.6107728533957728,
            -0.6083334988562047,
            0.601638100882538,
            0.5999246313958779,
            0.5985235026549504,
            -0.5965523067598398,
            -0.5941949612252009,
            0.5901735669442458,
            0.5899482862567567,
            -0.5861184613913467,
            0.5836903318774389,
            0.580402097633568,
            0.5795075026996408,
            -0.5781462511392528,
            -0.5725651181016802,
            0.5685355885643947,
            0.5650347803717629,
            -0.5645593786237318,
            0.5625565476637061,
            0.5586567653257851,
            -0.5578471251939097,
            0.5530913563350305,
            -0.5484676448941337,
            -0.548456189129413,
            -0.5478809517096964,
            -0.5412413826667215,
            -0.5366700851302945,
            0.5359234270619734,
            -0.532784946341891,
            -0.5271981721870103,
            0.5267912649085646,
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