{
    "significant_genes": {
        "Variable": [
            "AADAC",
            "ABCB4",
            "ABCD1P2",
            "AAK1",
            "AARSD1",
            "AARS2",
            "AANAT",
            "A2ML1",
            "A2M",
            "AAMP",
            "AACSP1",
            "ACMSD",
            "AATF",
            "ACSF3",
            "ABCC13",
            "ACCS",
            "A2M-AS1",
            "ABCC10",
            "ABHD1",
            "ABCD2",
            "A1CF",
            "AASDH",
            "ACOX1",
            "ABCC11",
            "ACAP3",
            "AAGAB",
            "A4GALT",
            "ACSBG2",
            "ABCF1",
            "ABHD12",
            "ABCA3",
            "ABCA6",
            "ABTB3",
            "ABAT",
            "ABCC5",
            "ACOD1",
            "AADACL2",
            "ABCF3",
            "ABCC1",
            "ACOT8",
            "ABCC6P1",
            "ACTN3",
            "ABCA2",
            "ACACB",
            "AA06",
            "ACKR2",
            "AAR2",
            "ABLIM3",
            "A1BG",
            "ACAA2",
            "ABL2",
            "ACP5",
            "ACOX2",
            "ACKR1",
            "ADAMTS15",
            "ACTL9",
            "ACTR3B",
            "ABCB9",
            "ACOT12",
            "ABCB7",
            "ACE",
            "ABTB1",
            "ABI1",
            "AACS",
            "ACTR3C",
            "ABHD4",
            "ABCA1",
            "ACAP1",
            "ACTG2",
            "ADAMTS10",
            "ABHD10",
            "ABLIM2",
            "ACBD6",
            "ACOT11",
            "ACP1",
            "ACSBG1",
            "ABCB1",
            "ACSL4",
            "ACTB",
            "ACTC1",
            "ACTL6A",
            "ABI3BP",
            "ACTN2",
            "ACTA2-AS1",
            "A2MP1",
            "ADAT3",
            "ADAM10",
            "ACSM1",
            "ACTR5",
            "ABHD2",
            "ACTR3P2",
            "ACR",
            "ABCD1",
            "ABCC12",
            "ABR",
            "ABHD16B",
            "ACSS2",
            "ABRAXAS2",
            "ACOT7",
            "ACAT1",
            "ABHD13",
            "ACAA1",
            "ADAMTS18",
            "AASS",
            "ACSM2B",
            "ACBD4",
            "ACAD10",
            "ADGRL2",
            "ABTB2",
            "A1BG-AS1",
            "ACTBP9",
            "ADAMTS7",
            "ACAD9",
            "ACIN1",
            "ACE2",
            "ACSS1",
            "ACTR3",
            "ABITRAM",
            "ACVR2B",
            "ACY3",
            "ABCA4",
            "ACSM3",
            "A4GNT",
            "ABHD14A",
            "ABCD4",
            "ACSS3",
            "ACTR3BP5",
            "ABCD3",
            "ACTA1",
            "ABHD6",
            "ABCA12",
            "ACAP2",
            "ABCA9",
            "ABHD11",
            "ABT1",
            "ADAMTS4",
            "ABCA5",
            "ABCC8",
            "ACTR2",
            "ABHD17C",
            "ACVR1B",
            "ADAM18",
            "AFF1",
            "ACKR4",
            "ABHD18",
            "ABHD16A",
            "ABHD3",
            "ADAM7",
            "ACAT2",
            "AICDA",
            "ACBD3",
            "ADAM1A",
            "ACTR3BP2",
            "ALOX15B",
            "ABI2",
            "ABCB10",
            "ADGRE3",
            "ACTG1P4",
            "ADGRG4",
            "ACYP1",
            "ADPRHL1",
            "ACAD8",
            "ADRA2C",
            "ADRA2B",
            "ACP2",
            "ADAMTS3",
            "ADAM6",
            "ACTRT2",
            "ABHD17B",
            "ABHD17A",
            "ABHD15",
            "ADAM12",
            "ACRBP",
            "ACTL7A",
            "ADGRA2",
            "ADD2",
            "ADAMTS6",
            "ADAM30",
            "ADSS1",
            "ACVRL1",
            "ADAM8",
            "AGPS",
            "ABCE1",
            "ADGRE1",
            "ACTL6B",
            "ACSM5",
            "ADM5",
            "ADAM5",
            "AFG2B",
            "ABCG2",
            "ABCC2",
            "ADGRV1",
            "ABCC6",
            "ADAMTSL1",
            "ACAD11",
            "ACTA2",
            "AATK",
            "ACTL10",
            "CCS",
            "ADPGK",
            "ABHD12B",
            "ABCF2",
            "ADAM2",
            "ABRA",
            "ANGPT4",
            "B3GNT2",
            "APOH",
            "AMN1",
            "AMN",
            "ABCA13",
            "ABCB5",
            "ADGRF2P",
            "AMBP",
            "ACVR1C",
            "ANKRD35",
            "AKAP17A",
            "ACTL7B",
            "ALOX12",
            "AKAIN1",
            "ASCL5",
            "KRTAP4-1",
            "AP3B2",
            "AFG2A",
            "ABCG1",
            "ADAMTS1",
            "AGFG1",
            "ADGRD1",
            "ADGRG2",
            "ADAMTS20",
            "ABCC4",
            "ADSS2",
            "ADCYAP1R1",
            "ADCK1",
            "ACSM2A",
            "ABI3",
            "ADAMTSL2",
            "ABCG8",
            "AGTR1",
            "BTF3P13",
            "AARS1",
            "AHSG",
            "ADH1C",
            "ANG",
            "ANAPC4",
            "ADORA3",
            "ACOT9",
            "ABCA7",
            "AOX1",
            "ADAP2",
            "ALKBH8",
            "ADRB3",
            "AEBP1",
            "AFAP1L2",
            "ABL1",
            "DNAAF10",
            "APPL2",
            "ADGRL4",
            "ACBD5",
            "AKAP3",
            "ARID4B",
            "ADCY5",
            "ASXL1",
            "ARMCX2",
            "BARX1",
            "AKNA",
            "ANKRD20A8P",
            "ANPEP",
            "ADH1A",
            "AKIRIN1",
            "AGGF1",
            "ACTR8",
            "C1orf159",
            "AIMP1",
            "ADAM9",
            "ACTR6",
            "AK9",
            "ADAMTS13",
            "ARC",
            "ADH4",
            "ANP32CP",
            "CCDC171",
            "GCSAM",
            "CAPN13",
            "CLEC3A",
            "ADGRG1",
            "ADAM29",
            "ANXA2P2",
            "AFM",
            "ACOT1",
            "ANXA8",
            "ANKRD65",
            "CD276",
            "BORCS6",
            "KRT4",
            "CHAC1",
            "ADGRE2",
            "AIM2",
            "ANLN",
            "ADARB2-AS1",
            "ANGEL1",
            "AFTPH",
            "CARD9",
            "ALPI",
            "BMP2K",
            "ANKRD17",
            "AAMDC",
            "CHADL",
            "EXOC3-AS1",
            "ABHD5",
            "ACER1",
            "ATP1A3",
            "ABCA17P",
            "C8orf58",
            "AMFR",
            "ALKBH6",
            "AMOT",
            "HORMAD1",
            "ALS2",
            "AZGP1P1",
            "ADCK5",
            "BTN3A1",
            "ALG6",
            "APH1B",
            "ASNS",
            "ACSL3",
            "ALX3",
            "CTH",
            "AGA",
            "CNTLN",
            "ENPP6",
            "ANK1",
            "ABCA8",
            "UROC1",
            "ANXA5",
            "ABLIM1",
            "C6orf141",
            "AKT1",
            "CD36",
            "ASGR2",
            "AFAP1",
            "AFMID",
            "ACD",
            "ACSL5",
            "CHRDL1",
            "KCNQ3",
            "IRS4",
            "AP4E1",
            "SCP2D1-AS1",
            "ABCC9",
            "ACOT13",
            "ATOSA",
            "C3P1",
            "AGMAT",
            "ATP6V0A2",
            "ACAN",
            "AJUBA",
            "BFSP2-AS1",
            "CC2D1B",
            "ABRAXAS1",
            "JMJD4",
            "ACTR1B",
            "ADARB1",
            "CYTH3",
            "AURKAP1",
            "CLVS1",
            "ARHGAP36",
            "ANKLE2",
            "ALG14",
            "ADORA1",
            "KANK1",
            "AKIP1",
            "ALX1",
            "ARK2C",
            "C1QTNF2",
            "ALPL",
            "CATIP-AS1",
            "AHCY",
            "ANKS3",
            "ABCB11",
            "ATMIN",
            "KRTAP3-3",
            "EGFL7",
            "ALDH7A1",
            "ALDH1A3",
            "B4GALT5",
            "SDS",
            "ADD3",
            "ADARB2",
            "APBA2",
            "BMAL2-AS1",
            "AGPAT2",
            "ACKR3",
            "BRIX1",
            "AQP9",
            "GTF2H1",
            "GYPB",
            "AGO1",
            "ASB10",
            "ARLN",
            "ARHGDIG",
            "ARFIP1",
            "CCNE2",
            "ASCC3",
            "DIABLO",
            "KLHL25",
            "AIRE",
            "APC2",
            "PRR23D1",
            "CENPA",
            "ALX4",
            "PTGES",
            "CSMD3",
            "MARCHF4",
            "AOC4P",
            "BORCS8",
            "ATF7IP2",
            "CPS1",
            "DPH2",
            "ZNF660",
            "ADAT1",
            "AGBL2",
            "SSX2B",
            "ADGRF5",
            "CBY3",
            "ATP23",
            "ANOS2P",
            "AGPAT4",
            "ADAMTS19",
            "ADAM23",
            "AIFM1",
            "CYP3A51P",
            "LIG4",
            "ZNF34",
            "C8orf33",
            "AVP",
            "AGAP6",
            "VKORC1L1",
            "DCX",
            "ADAM3B",
            "IQCF4P",
            "ADGRG3",
            "ALG11",
            "CARS1-AS1",
            "CIMIP4",
            "GABRG1",
            "HOXC8",
            "CACNA2D1",
            "ERCC6",
            "ASPA",
            "GSTM5",
            "CAMK2B",
            "EPS15P1",
            "CLTCL1",
            "TUBAL3",
            "RNU2-22P",
            "CA8",
            "BTF3P12",
            "SMLR1",
            "ARVCF",
            "ALG5",
            "ARHGAP12",
            "AP1S3",
            "C3orf49",
            "FAM13A",
            "FOXP1-AS1",
            "APOBEC3B",
            "GRPR",
            "BRINP2",
            "BEND5",
            "AKTIP",
            "ARRDC4",
            "ARF1P1",
            "ATP11A",
            "EBF2",
            "AIG1",
            "BEX4",
            "PLCB1",
            "ASAP1-IT2",
            "ICAM5",
            "ADD1",
            "GCM2",
            "CEACAM4",
            "CNPY4",
            "APIP",
            "ALOX12B",
            "AGAP2",
            "ADNP2",
            "C8G",
            "BEST1",
            "ARL14",
            "ZC3H10",
            "ELAPOR1",
            "SLC28A2",
            "GUCY1A1",
            "APOF",
            "HMCN2",
            "C22orf39",
            "GPHB5",
            "FRRS1",
            "HCG4",
            "ANKRD13B",
            "ADGRA1",
            "FDXACB1",
            "ERGIC1",
            "ABHD8",
            "FXYD7",
            "SYT4",
            "PRR23D2",
            "ANXA8L1"
        ],
        "Coefficient": [
            0.11038836263635274,
            0.09109339435314445,
            -0.08814695071358064,
            -0.07758130942673751,
            -0.07466372668195939,
            -0.06682418706384274,
            0.06553409820862363,
            0.06196000847895644,
            -0.059827417413689715,
            0.059669811890477854,
            0.05815012374660407,
            -0.055933204169441135,
            0.054691998006770104,
            0.054091445693279123,
            0.05361075906246812,
            0.052950445406000926,
            0.05101788799444799,
            0.04968635670833672,
            -0.0492407461660383,
            -0.049059610586522445,
            -0.04885913971741389,
            -0.04711471100013133,
            -0.046862582611648,
            -0.04432258727911205,
            -0.04321990299207623,
            0.04250804726833286,
            -0.04185047134466697,
            -0.041450155519683916,
            -0.04059262621741035,
            0.04033354688051578,
            -0.040114226584081286,
            -0.03887874153025657,
            -0.03886978219425966,
            0.03735120799270813,
            0.03693664673591061,
            -0.03668858887187071,
            -0.03599013348105871,
            -0.03514117919468583,
            -0.03509130417614397,
            0.03482955206493523,
            -0.03468447872474862,
            -0.03415326172606051,
            -0.03414733224381228,
            0.03215426623145043,
            0.03193460036165935,
            0.031063774659863024,
            -0.03104841599499905,
            0.0309235375271327,
            -0.030098964929901474,
            0.029802449875713028,
            0.028822295871727056,
            0.027748657637670246,
            0.027627532300219186,
            0.026806403577430873,
            -0.026666121792671416,
            -0.026248488278661466,
            0.025777050090358772,
            0.025629617234674325,
            0.025543173590127106,
            -0.025324383842938954,
            -0.02486205329789285,
            -0.024644262862230374,
            0.023693014734472398,
            -0.02367577949762316,
            -0.02354632030607854,
            0.02349162742650771,
            -0.0231635517456388,
            -0.02280588054371097,
            0.02260236960154246,
            -0.02257156970880619,
            0.022487572925586428,
            -0.021939547139010068,
            -0.021393894226646403,
            0.020854552668268588,
            0.020603229296373673,
            -0.02024290634789999,
            -0.020095791097983876,
            -0.02004864252612589,
            -0.020019265605719382,
            0.019525932558543572,
            0.01929719801300367,
            -0.018074429841820637,
            0.01741281223200265,
            0.01707414266197317,
            0.01704314490031192,
            -0.01685443724316913,
            0.016732819231299073,
            0.01669121587983251,
            0.016640928284465697,
            0.016619977283050445,
            0.016594687276544152,
            0.01655819663373891,
            -0.0164246302191952,
            -0.015956314596940604,
            -0.01549882362333602,
            0.01542762769604955,
            0.01536530147053191,
            -0.015206747517479465,
            0.015179904456046554,
            -0.014955651033846107,
            0.014308151489190749,
            0.01422784039746138,
            0.014177501348515831,
            0.013975572391994328,
            0.013971003103108328,
            0.013964955892803327,
            0.013773095723095858,
            0.013670700036033646,
            0.013646032537771635,
            0.013183400279827343,
            -0.013182903264968657,
            0.013136376101491112,
            0.013132977526226738,
            0.012559302115322715,
            0.012556958978776444,
            -0.012496275388520188,
            0.012392296883249778,
            0.012252869287553746,
            -0.012231634747286379,
            0.012225785122381054,
            -0.01217263849296942,
            -0.012129986612401833,
            0.012095522034833061,
            0.012017711991928604,
            -0.01189343461838393,
            0.011869152203624278,
            0.011809883149007447,
            -0.011687664481335775,
            -0.011649289936891166,
            0.011471141060091467,
            -0.011406186869884758,
            0.011331128846505337,
            -0.01108270772166558,
            0.01097033201886818,
            0.010932467548158556,
            -0.010895942031610876,
            -0.010614157848234907,
            0.010415051524937989,
            0.010313960065615772,
            0.01029923959978605,
            -0.010178280853466818,
            0.009963242194860276,
            0.009912727802260813,
            -0.00969597155671252,
            0.009619980945809108,
            -0.009540155926324078,
            0.009122519637647859,
            0.008856180292542454,
            0.008830700074738476,
            -0.008704730074013418,
            0.008657890651645118,
            -0.008569511997325061,
            0.008545679465517039,
            -0.008339121437889176,
            0.008330085002745631,
            -0.008253295765075093,
            0.00820142712547488,
            0.007985598807289985,
            -0.007947600823296373,
            0.007914564421515845,
            0.007890061462234808,
            -0.007793755029550409,
            -0.007586411185200427,
            0.0071342733460932365,
            0.00712694897305532,
            -0.007119036871125059,
            0.007113174131990367,
            0.0071077388436471,
            -0.007082464171035078,
            0.007039466862565186,
            -0.006968895725300421,
            -0.00685163448893786,
            0.006798676863310484,
            0.0067648139414536075,
            -0.006731006683878825,
            0.006689003890489683,
            0.006682318751214322,
            -0.006571242136498898,
            -0.006322337046830347,
            -0.006239402467487405,
            -0.006126357580830127,
            -0.006034138171137878,
            -0.005825559036124719,
            0.0057756749487029,
            0.00557086223817422,
            -0.005441265376510224,
            -0.005401373105080105,
            0.00534275504322025,
            -0.00533038705277931,
            0.005195636808202559,
            -0.005081227079194557,
            0.004900414933654345,
            0.0048445236099382396,
            -0.004836008954609639,
            0.004829403371356735,
            -0.004612896028386627,
            -0.0045801040594386595,
            -0.004549650262728653,
            0.004503555826508796,
            -0.004348512371365984,
            0.0042314798357204406,
            0.0041597195215905495,
            0.004140689031161525,
            0.003954517293954974,
            0.0038557885072937233,
            -0.0038497500533194477,
            0.003783700014839974,
            -0.003718863885759778,
            0.003601402332131396,
            -0.003506666817758317,
            -0.0034779607340142842,
            -0.0034756699430065563,
            -0.003465451466668747,
            0.003421797313398008,
            0.003410846742510247,
            -0.003329878793250941,
            -0.003189049133799115,
            0.0031821896750705444,
            -0.0031788385297744646,
            -0.0031068789639924514,
            -0.0030933765195629553,
            0.0030861528813555705,
            -0.0030788795144366843,
            -0.003052035793466432,
            0.0030280246185013307,
            -0.0030189594750043096,
            0.002963593842629973,
            0.0028729352192881207,
            -0.002815744568020026,
            -0.002795715467261354,
            -0.002771119529083515,
            0.0027707863035808596,
            -0.002752463546765165,
            0.002743020871942015,
            -0.0027338920579559707,
            -0.002689377392244689,
            0.00268068612289586,
            0.0026425852354787587,
            0.0026111935215933834,
            0.002568723850880214,
            -0.002534344612681921,
            -0.002442277611227635,
            0.0023751114421183025,
            0.0023554669062810347,
            0.0023028564194374082,
            -0.002263129768176877,
            -0.0022570984776977337,
            0.00223487246683167,
            0.002223921352284411,
            -0.0022093097620863042,
            -0.0021917738988246694,
            0.002160950620687832,
            0.002150994334304988,
            0.00207527821650067,
            -0.002011685775897707,
            -0.0019237275028197074,
            -0.0018958177238859349,
            -0.0018693320468665799,
            0.0018690963211279441,
            0.001831478411651696,
            -0.0017616868703243713,
            0.0017611359403714914,
            0.0017553965501746892,
            0.0017372248267829113,
            0.0017267699802234195,
            -0.0017178412824191715,
            -0.0016918034534522096,
            -0.0016592443940753481,
            -0.001638975183767553,
            -0.0016193412495143775,
            0.001618740490950762,
            0.0016044673458399353,
            -0.0015743409579719522,
            0.0015712281468086536,
            0.0015455688989836124,
            -0.0015128934636523194,
            -0.001495634343544525,
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