{
    "significant_genes": {
        "Variable": [
            "AADAC",
            "ABCB4",
            "ABCD1P2",
            "AAK1",
            "AARSD1",
            "AANAT",
            "AARS2",
            "A2ML1",
            "A2M",
            "AACSP1",
            "AAMP",
            "ACMSD",
            "ABCC13",
            "AATF",
            "ACSF3",
            "ACCS",
            "A2M-AS1",
            "A1CF",
            "ABCC10",
            "ABCD2",
            "ABHD1",
            "ACOX1",
            "ACAP3",
            "ABCC11",
            "AAGAB",
            "AASDH",
            "ACSBG2",
            "ABCF1",
            "ABHD12",
            "A4GALT",
            "ABCA3",
            "ABTB3",
            "ABAT",
            "ABCC5",
            "ABCA6",
            "ACOD1",
            "ABCC6P1",
            "AADACL2",
            "ABCF3",
            "ACOT8",
            "ACTN3",
            "ABCC1",
            "AA06",
            "ABCA2",
            "ACACB",
            "ACKR2",
            "A1BG",
            "ABLIM3",
            "AAR2",
            "ACAA2",
            "ABL2",
            "ACOX2",
            "ACP5",
            "ACKR1",
            "ADAMTS15",
            "ACTL9",
            "ACOT12",
            "ACTR3B",
            "ABCB9",
            "ACAP1",
            "ACE",
            "ABCB7",
            "ABI1",
            "ACTR3C",
            "ABTB1",
            "ABHD10",
            "ABHD4",
            "ADAMTS10",
            "ACTG2",
            "ACBD6",
            "AACS",
            "ABLIM2",
            "ABCA1",
            "ACP1",
            "ACSL4",
            "ACOT11",
            "ACTB",
            "ACTL6A",
            "ACSBG1",
            "ABCB1",
            "ABCD1",
            "ACTC1",
            "ACTN2",
            "ACTR5",
            "ABI3BP",
            "ADAM10",
            "ACTA2-AS1",
            "ACSM1",
            "ADAT3",
            "ACR",
            "ABHD2",
            "ABR",
            "ACTR3P2",
            "ACAT1",
            "ACSS2",
            "ACBD4",
            "ABTB2",
            "ADAMTS18",
            "ABRAXAS2",
            "ACAA1",
            "ABHD16B",
            "ACAD9",
            "ABITRAM",
            "ACOT7",
            "AASS",
            "ACIN1",
            "ADAMTS7",
            "A2MP1",
            "ACSM2B",
            "ABCC12",
            "ABCA5",
            "ACAD10",
            "ABHD13",
            "ABHD14A",
            "ACSS1",
            "ACSM3",
            "ADGRL2",
            "ACTBP9",
            "ABHD11",
            "ACE2",
            "ABCA4",
            "ACTR3",
            "ABCA9",
            "ACVR2B",
            "A1BG-AS1",
            "ABCD3",
            "ACTR3BP5",
            "ACSS3",
            "ABCD4",
            "ACTA1",
            "ABHD17C",
            "ABCA12",
            "ACY3",
            "ACAP2",
            "ABHD6",
            "ABHD16A",
            "ABT1",
            "ABCC8",
            "ADAMTS4",
            "ADAM18",
            "AFF1",
            "ACKR4",
            "ACTR2",
            "ACVR1B",
            "ABHD15",
            "ABHD18",
            "AICDA",
            "ADAM7",
            "ADAM1A",
            "ABHD3",
            "ACTR3BP2",
            "ACBD3",
            "A4GNT",
            "ADGRG4",
            "ALOX15B",
            "ADGRE3",
            "ADAMTS3",
            "ADPRHL1",
            "ABI2",
            "ACAT2",
            "ADRA2C",
            "ACYP1",
            "ADAMTS6",
            "ACAD8",
            "ABHD17A",
            "ADAM6",
            "ACTL7A",
            "ABCB10",
            "ACTG1P4",
            "ADGRA2",
            "ADD2",
            "ADAM12",
            "ACRBP",
            "ABHD12B",
            "ADRA2B",
            "ABHD17B",
            "ADSS1",
            "ADAM8",
            "ADGRE1",
            "ABCG2",
            "ADM5",
            "ACP2",
            "ADAM30",
            "ACTL6B",
            "AGPS",
            "ADAMTSL1",
            "AFG2B",
            "ABCE1",
            "ADAM5",
            "AATK",
            "ACVRL1",
            "ACAD11",
            "ACTA2",
            "ACTRT2",
            "ABCF2",
            "ADGRV1",
            "ACSM5",
            "ADAM2",
            "CCS",
            "ADPGK",
            "ACVR1C",
            "ADGRF2P",
            "AMBP",
            "ACTL10",
            "ADGRD1",
            "APOH",
            "ANGPT4",
            "B3GNT2",
            "ABCA13",
            "AMN1",
            "ABCB5",
            "AMN",
            "ABCG1",
            "ANKRD35",
            "ASCL5",
            "AP3B2",
            "AKAIN1",
            "AKAP17A",
            "ABCC4",
            "AARS1",
            "ACSM2A",
            "AGFG1",
            "ABCC2",
            "ABCC6",
            "ADCYAP1R1",
            "KRTAP4-1",
            "ADSS2",
            "ADGRG2",
            "ADCK1",
            "ADORA3",
            "ANG",
            "ABRA",
            "ALOX12",
            "ADAMTSL2",
            "AAMDC",
            "AFG2A",
            "AGTR1",
            "ACTL7B",
            "AHSG",
            "BTF3P13",
            "ANAPC4",
            "ADAMTS1",
            "ADAMTS20",
            "ABCG8",
            "ADH1C",
            "ACOT9",
            "AEBP1",
            "AFAP1L2",
            "AIMP1",
            "ABCA17P",
            "AOX1",
            "DNAAF10",
            "ARID4B",
            "AKIRIN1",
            "ABI3",
            "AKNA",
            "CCDC171",
            "ARMCX2",
            "ADAM9",
            "ADCY5",
            "ADAP2",
            "ANP32CP",
            "ALKBH8",
            "ADARB2-AS1",
            "ADGRL4",
            "ABCA7",
            "APPL2",
            "ANKRD20A8P",
            "ABCC9",
            "BARX1",
            "ACTR6",
            "ASXL1",
            "ADRB3",
            "ACBD5",
            "ADH1A",
            "GCSAM",
            "C1orf159",
            "ADH4",
            "ACTR8",
            "CAPN13",
            "AGGF1",
            "CLEC3A",
            "ADAMTS13",
            "AFM",
            "ANXA8",
            "ANPEP",
            "CHAC1",
            "ARC",
            "ADAM29",
            "CARD9",
            "ADGRG1",
            "CD276",
            "ANXA2P2",
            "ANKRD17",
            "EXOC3-AS1",
            "ADGRE2",
            "ANLN",
            "ALG6",
            "AADAT",
            "KRT4",
            "AKAP3",
            "ANGEL1",
            "ENPP6",
            "ANKRD65",
            "BMP2K",
            "AIM2",
            "ALPI",
            "ABHD5",
            "ADCK5",
            "AK9",
            "BORCS6",
            "ACOT1",
            "AMFR",
            "ALKBH6",
            "CHADL",
            "C8orf58",
            "AMOT",
            "AZGP1P1",
            "ASNS",
            "ATP1A3",
            "C6orf141",
            "ASGR2",
            "AFTPH",
            "ACSL3",
            "BTN3A1",
            "ALX3",
            "CNTLN",
            "AFAP1",
            "CTH",
            "IRS4",
            "ABRAXAS1",
            "ALS2",
            "ABL1",
            "APH1B",
            "UROC1",
            "HORMAD1",
            "CD36",
            "ANK1",
            "ADARB1",
            "SCP2D1-AS1",
            "ACSL5",
            "ADARB2",
            "ALPL",
            "ACAN",
            "CYTH3",
            "ANXA5",
            "ACER1",
            "AGMAT",
            "AKT1",
            "AFMID",
            "ATOSA",
            "CHRDL1",
            "ADAM23",
            "GYPB",
            "KCNQ3",
            "AP4E1",
            "AGA",
            "CLVS1",
            "ATP6V0A2",
            "AURKAP1",
            "AKIP1",
            "JMJD4",
            "ANKS3",
            "ARHGAP36",
            "ACHE",
            "AHCY",
            "C1QTNF2",
            "ANKLE2",
            "SDS",
            "CATIP-AS1",
            "KRTAP3-3",
            "B4GALT5",
            "ADORA1",
            "BMAL2-AS1",
            "ARK2C",
            "ATMIN",
            "AMER1",
            "ALPP",
            "ACOT13",
            "KANK1",
            "AJUBA",
            "AGPAT2",
            "ALDH7A1",
            "KLHL25",
            "C3P1",
            "AQP9",
            "ARLN",
            "AIG1",
            "GTF2H1",
            "CC2D1B",
            "AOC4P",
            "AHCYL1",
            "ABHD8",
            "APBA2",
            "ACKR3",
            "BRIX1",
            "EGFL7",
            "ACD",
            "ALG14",
            "AIRE",
            "CCNE2",
            "ASB10",
            "ADGRG3",
            "ADA",
            "ATF7IP2",
            "AGO1",
            "ASPRV1",
            "AGPAT3",
            "ASCC3",
            "BFSP2-AS1",
            "ALDH1A3",
            "BORCS8",
            "ARHGDIG",
            "DIABLO",
            "AGBL2",
            "MARCHF4",
            "CENPA",
            "ARFIP1",
            "ZNF34",
            "ABLIM1",
            "ZNF660",
            "ADCY1",
            "ANOS2P",
            "APC2",
            "AIFM1",
            "ARF1P1",
            "CBY3",
            "ATP23",
            "HCG27",
            "CNPY4",
            "VKORC1L1",
            "CYP3A51P",
            "ASPA",
            "ARHGAP12",
            "EPS15P1",
            "C3orf49",
            "CARS1-AS1",
            "ADGRL1",
            "PRR23D1",
            "ALG5",
            "ALX1",
            "GRPR",
            "ALOX12B",
            "SSX2B",
            "ALDH3A1",
            "C20orf202",
            "GSTM5",
            "PLCB1",
            "CLTCL1",
            "SMLR1",
            "C8orf33",
            "CAMK2B",
            "AGPAT4",
            "BRAF",
            "IQCF4P",
            "ACTR1B",
            "SLC28A2",
            "HOXC8",
            "ADAMTS19",
            "ADI1",
            "FDXACB1",
            "CA8",
            "CSMD3",
            "ADAM3B",
            "AGPAT1",
            "ERCC6",
            "ANGPT1",
            "EBF2",
            "APIP",
            "BEX4",
            "ARF5",
            "APOBEC3C",
            "FXYD7",
            "AGAP2",
            "FOXP1-AS1",
            "CATSPER2",
            "AKAP8L",
            "BTF3P12",
            "ARHGAP11B",
            "FAM13A",
            "DPH2",
            "FGD4",
            "BEND5",
            "BRINP2",
            "C5orf24",
            "APEX1",
            "ARMCX5-GPRASP2",
            "APOBEC3B",
            "CEACAM4",
            "RPL10L",
            "TUBAL3",
            "ALPK3",
            "ARMC6",
            "TEDC2",
            "SLC25A2",
            "CCDC167",
            "ASAP1-IT2",
            "ANKRD22",
            "SYT4",
            "CRELD2",
            "AEN",
            "LIG4",
            "APOF",
            "AKT2",
            "KRTAP4-11",
            "ADGRA1",
            "ENTHD1",
            "DCX",
            "PTGES",
            "MKX",
            "EXTL3-AS1",
            "ARSD",
            "ARVCF",
            "CASQ2",
            "AP2M1",
            "DCHS2",
            "AFP",
            "GRIN2C",
            "VWA5B2",
            "ATP11A",
            "ARSL",
            "AGAP1",
            "ELAPOR1",
            "CCDC141",
            "INTS14",
            "PRR23D2",
            "ANXA8L1"
        ],
        "Coefficient": [
            0.11100462202894104,
            0.09175821011316361,
            -0.08757209951602955,
            -0.07817196768940243,
            -0.07436498776741172,
            0.06712489076641938,
            -0.06708588431514842,
            0.060562786044929144,
            -0.05884087406745553,
            0.05854019351893987,
            0.058007092689275896,
            -0.05618110727712043,
            0.05430832200589895,
            0.05385669492520649,
            0.05350557890024192,
            0.05319953198679877,
            0.05176492882074942,
            -0.050819693908615016,
            0.04950423750091246,
            -0.049299258400216144,
            -0.049016468386656915,
            -0.04827198802285287,
            -0.0444863435220922,
            -0.04417549001094434,
            0.04360192642642871,
            -0.04341469236406548,
            -0.042717617404393345,
            -0.04083901840833156,
            0.040804036931015274,
            -0.040126001465961895,
            -0.039595882957302105,
            -0.03902287226793804,
            0.03813318983540836,
            0.03806570293367573,
            -0.037778758793189926,
            -0.03616152000423582,
            -0.035912270776459226,
            -0.0355642598975734,
            -0.035411254524025264,
            0.03538243151727492,
            -0.03462906458067749,
            -0.032809745307748696,
            0.03246251476328888,
            -0.03231651799663506,
            0.03220832582786316,
            0.03219563844077787,
            -0.03173446132244371,
            0.03135528224911643,
            -0.03110706732563875,
            0.029266032744670514,
            0.029038227083886987,
            0.027897380612252786,
            0.027713817121226888,
            0.027647540523152964,
            -0.027183509758038887,
            -0.02587755415509585,
            0.02559961337119695,
            0.02541835772823133,
            0.024658401867876416,
            -0.024252761438811544,
            -0.024127123904909488,
            -0.023666883721049338,
            0.0236546210040863,
            -0.02325727659149048,
            -0.023115960700474874,
            0.023063795695165677,
            0.02236853513978194,
            -0.022368371033892828,
            0.022255017987711692,
            -0.02209737415344487,
            -0.02177584886562725,
            -0.021446373404335292,
            -0.02143860752551233,
            0.020668351337292546,
            -0.0204531983877962,
            0.020347862746177954,
            -0.01965377394878904,
            0.0195863029966864,
            -0.019429086776216856,
            -0.01903343077655721,
            -0.01876854591609526,
            0.018611179860428085,
            0.017899086315573857,
            0.0178331210352443,
            -0.01745415102251721,
            0.01743429424585329,
            0.017088575296385463,
            0.016992092572522776,
            -0.016640322387519172,
            0.01638594682114345,
            0.016342408586632513,
            -0.016183152176731472,
            0.015591100468261532,
            -0.015401757313582105,
            0.015292475127082107,
            0.01525127107020312,
            0.01520355964827701,
            0.014909343913816962,
            -0.01489623994782976,
            0.014816642555318796,
            0.014765068888554942,
            0.014599419847573831,
            0.014228590744254855,
            0.014089387348365392,
            0.014065669009779532,
            0.013947202810567313,
            0.013924677125668916,
            0.013838036194529108,
            0.01380536251791716,
            -0.013695234323590495,
            -0.013625077955073601,
            0.013483517045995761,
            0.013392588465965078,
            0.01329334477778566,
            -0.01321297043841624,
            -0.013045240395277177,
            0.013023986078231851,
            -0.012965957305896255,
            0.012736159396957042,
            0.012684593348203791,
            -0.012574277532216668,
            0.012541939524237529,
            -0.012335468010710254,
            -0.012331967544954065,
            0.012293484626826489,
            -0.012274605282775347,
            0.012151026287811255,
            0.012090973387000608,
            -0.01202879601345365,
            -0.011974381475661496,
            0.011889421667190841,
            -0.011336594310663972,
            0.011074429108127667,
            0.011021305578037757,
            0.010936270330697178,
            -0.010910947889687364,
            0.010841844202975012,
            0.010779652553401409,
            -0.010748865360607634,
            0.01022400959308997,
            0.010159126408283621,
            -0.010017787739466127,
            0.00973118160653151,
            -0.009459669519311298,
            -0.009377669788666495,
            0.009305443609194245,
            -0.009132874041751126,
            0.009124037625651584,
            -0.008995102370220606,
            0.00880339405192275,
            0.008757764710895751,
            0.008722011043496613,
            0.008712324186477887,
            -0.008435186691019732,
            -0.008357028941583421,
            0.008102257669506386,
            -0.008008257792081516,
            0.007961261334130207,
            0.007773787318296867,
            0.0075903104950588805,
            -0.00752409939246777,
            0.0074437028616643405,
            0.0072448200145293976,
            -0.007227956929910157,
            0.007041616484949581,
            0.0069647200339482416,
            0.0068917375605148466,
            -0.006848635686731938,
            0.006845107038879605,
            -0.006810194186951111,
            0.006802674535411355,
            -0.006761900396073765,
            0.006706764606175913,
            0.006625542922418567,
            0.006404473317799543,
            -0.0063471792484191105,
            -0.006327806378167878,
            -0.006286712875996396,
            0.006268243619810063,
            0.006089868698508931,
            -0.00598117732525104,
            0.005892964469214542,
            -0.005865584299341951,
            0.005804057150883085,
            -0.005784360893387304,
            -0.005756975975304278,
            -0.005713993011333812,
            -0.0056866263719013025,
            0.005682795164225336,
            -0.005626859979046029,
            -0.005577838552978013,
            0.00557688809717055,
            -0.005559671239644924,
            0.005290455681904672,
            0.005147668307374621,
            0.005010280972233674,
            -0.004610656729217433,
            0.004227191430169457,
            0.00421701695445624,
            -0.004104208918295894,
            0.004027396882748244,
            -0.00402121544652235,
            -0.003954658596521976,
            -0.0039430778442710165,
            0.003860615270741248,
            0.003857153070605338,
            0.003824058035424767,
            -0.0038017964073910424,
            -0.0037606871799293943,
            -0.0037538819724622827,
            -0.0035823762818852144,
            0.0035603694605471224,
            -0.003537438809004468,
            0.0033784911568208063,
            -0.003345744114757494,
            0.003324276250493062,
            -0.0033161214337859178,
            -0.0032932933642918216,
            -0.003282235656726316,
            0.0032528595477259474,
            0.0032410489676244787,
            -0.0032360056544829302,
            -0.003231432150880573,
            0.003139856136898228,
            0.003074105176143174,
            -0.003061396994907384,
            -0.003013856600987758,
            0.003004010254960883,
            -0.0029833373613085174,
            0.0029112161349977876,
            0.002910308896224121,
            0.002775680734959317,
            0.0027687535171141997,
            -0.002767042793112894,
            -0.0027634908174389594,
            -0.0027291366703384085,
            0.0026652475611241384,
            -0.0025946318287699637,
            -0.0025865254890019983,
            0.002540435300398208,
            0.0024704810012866245,
            0.0024505092417721618,
            -0.0023806671481782084,
            0.00236830534497186,
            -0.0023223908150692405,
            -0.0022285729613896236,
            0.002222369322605833,
            0.002208777421909147,
            -0.0021348474347993676,
            -0.0021006102005125754,
            0.0020792595681533407,
            -0.002030202482686014,
            0.001985534028603535,
            -0.001968490510460489,
            -0.001948549384595329,
            0.0019409267112427148,
            0.001914833126964856,
            0.0019025475752416311,
            0.0018719577446272093,
            -0.0018650930917404524,
            0.0018283235323346316,
            -0.001822327825247834,
            -0.001817193636659311,
            -0.0018087708365703535,
            -0.0017699368711783369,
            -0.0017055444005786356,
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