{
    "significant_genes": {
        "Variable": [
            "A1BG-AS1",
            "ABCA11P",
            "ABCC6P1",
            "AC009237",
            "AASS",
            "AATK",
            "ACP5",
            "ABCC2",
            "AANAT",
            "ABAT",
            "AC003973",
            "ADAMTS1",
            "ABCC1",
            "ABCA9",
            "AAR2",
            "ABCB4",
            "ACSF2",
            "ADRA2A",
            "AAED1",
            "ABCB6",
            "ABCC9",
            "AC009502",
            "ABHD8",
            "AC005537",
            "ADRB1",
            "ABCC6",
            "A2M-AS1",
            "AADAT",
            "ABI2",
            "ABCC8",
            "AC124997",
            "ABCA13",
            "AARS",
            "ABCC5",
            "AASDH",
            "A4GALT",
            "AC007680",
            "ACTR8",
            "ABCG5",
            "ABCA1",
            "ABCC11",
            "ACSBG2",
            "A1BG",
            "AC104537",
            "AC084219",
            "ABCB9",
            "ABHD1",
            "ADAMDEC1",
            "ABRA",
            "ACADL",
            "ANKRD36BP2",
            "ABCA17P",
            "ABR",
            "AC012360",
            "AC005592",
            "AARS2",
            "ADAMTS3",
            "ABCD4",
            "AC099850",
            "ACTR10",
            "A1CF",
            "ACOT7",
            "ABLIM3",
            "ABCC13",
            "AC091133",
            "ADAM7",
            "ABHD14A",
            "AACSP1",
            "ABCA8",
            "AFAP1-AS1",
            "ABHD17A",
            "ABHD10",
            "ACLY",
            "ABL2",
            "AC004490",
            "AC018816",
            "AF198444",
            "AC005256",
            "ADGB",
            "AC007349",
            "AACS",
            "ADCY10",
            "ABCD1",
            "ABHD16B",
            "ADAMTS14",
            "ADAM6",
            "ABCF1",
            "AK096335",
            "ANKRD37",
            "ACER3",
            "AGAP11",
            "ADORA2A-",
            "ACTR1A",
            "ACY1",
            "ACO1",
            "ADAM18",
            "AGAP2-AS1",
            "AC007787",
            "ABCA3",
            "AC100830",
            "ABCD1P2",
            "ABT1",
            "ADORA2A",
            "ACTR3C",
            "ACOT6",
            "ABCB7",
            "AC007557",
            "ADH1A",
            "ACOT4",
            "AL590762",
            "AC005785",
            "ACOT11",
            "ANKRD30BL",
            "ADAMTS4",
            "ADAMTS5",
            "ACOT9",
            "ACTN3",
            "ACP6",
            "ABCF2",
            "ADCK5",
            "ADAMTS16",
            "AAMP",
            "AK093205",
            "AC009120",
            "AB488780",
            "A4GNT",
            "ABCC12",
            "ANAPC13",
            "AC009947",
            "AC007401",
            "ALG2",
            "ACTA1",
            "ACSL1",
            "ADARB2",
            "ALK",
            "AC005838",
            "AAAS",
            "ADAM23",
            "AKR1A1",
            "ALAS2",
            "ALDH7A1",
            "ARRDC1",
            "AK291611",
            "ADIRF-AS1",
            "ADRA2B",
            "AL132709",
            "AGPAT4-IT1",
            "ACOT8",
            "AX746710",
            "ANKRD54",
            "ADARB2-AS1",
            "ABCA12",
            "AC012065",
            "AIMP2",
            "AC079807",
            "ABHD6",
            "AC092667",
            "AK094733",
            "AFF3",
            "AK024936",
            "ACTR3P2",
            "ALG1",
            "AJUBA",
            "AF086126",
            "ADM5",
            "ABCG8",
            "ABI3BP",
            "AC004538",
            "ACSL6",
            "ACTN2",
            "ADAMTS6",
            "AC013733",
            "ADH5",
            "ALOX5AP",
            "ADAMTSL2",
            "AF086154",
            "ADORA1",
            "ADAM5",
            "ACTA2-AS1",
            "AGAP9",
            "AC018462",
            "AC114752",
            "AC092660",
            "ARHGEF26",
            "AC013463",
            "ASAH2B",
            "AC009133",
            "ABCB8",
            "AC005498",
            "ANKRD33B",
            "AMIGO1",
            "ACD",
            "ADAM12",
            "ABHD4",
            "AC025442",
            "ABHD3",
            "ADPRHL1",
            "ABCC4",
            "AKAP3",
            "ALOX15",
            "ANAPC11",
            "ADO",
            "AF289551",
            "ADAD2",
            "AX746690",
            "A2M",
            "ARL14",
            "AC064852",
            "CDKN2B-AS1",
            "ABHD13",
            "ACTL6B",
            "ACVRL1",
            "ALKBH8",
            "ADIRF",
            "AK025117",
            "AGXT",
            "ANKRD36C",
            "AKIP1",
            "BC047615",
            "ADARB1",
            "AADAC",
            "ADORA3",
            "AK024119",
            "AC012499",
            "ABTB1",
            "AK098263",
            "ANXA2P3",
            "ANKRD33",
            "ACTG1P4",
            "AC003989",
            "ALKBH5",
            "ARHGAP31",
            "AC002310",
            "ADAM10",
            "ANO9",
            "ABCG4",
            "AC004692",
            "BRS3",
            "AP006222",
            "ACOT1",
            "AC004941",
            "ADAM28",
            "ACTL6A",
            "ADHFE1",
            "AK022793",
            "CASC5",
            "AES",
            "AC067956",
            "AIRE",
            "AKT1S1",
            "ADAMTS9",
            "ARHGEF33",
            "AF086102",
            "ANO10",
            "ANGPTL3",
            "ANKRD22",
            "AAK1",
            "AC002059",
            "ACRV1",
            "AC079305",
            "AKR1B10",
            "ATP8A2",
            "AC024560",
            "ADRA1A",
            "ARHGAP39",
            "ADH6",
            "ADAM9",
            "AKR1B1",
            "ACOX1",
            "ADAT2",
            "ASB16-AS1",
            "ANGPTL4",
            "ACR",
            "ANKRD20A8P",
            "AKR1E2",
            "ACADVL",
            "AK025288",
            "ADAMTS20",
            "ADAM3A",
            "AHCTF1",
            "AC144652",
            "ABCG2",
            "ACVR1B",
            "DLG5",
            "ADPRM",
            "AC092192",
            "ANO8",
            "ADAMTSL4",
            "ANKRD18B",
            "A2MP1",
            "ASS1",
            "ACER1",
            "ABCA2",
            "AHI1",
            "AK5",
            "C14orf37",
            "ACPT",
            "AL133493",
            "ACYP2",
            "ACPP",
            "ADAMTSL3",
            "ADRM1",
            "AK056982",
            "FLVCR1-AS1",
            "ARHGAP42",
            "ACSBG1",
            "ADCY8",
            "AADACL2",
            "A2ML1",
            "ADM",
            "ATP13A4-",
            "ANKRD49",
            "ABCC3",
            "ACOX3",
            "BOLL",
            "ANKRD29",
            "ADAM17",
            "AX746627",
            "ACSL4",
            "BBS5",
            "BC047644",
            "AHCTF1P1",
            "ARHGAP32",
            "ABCC10",
            "ALB",
            "AC012531",
            "BC045789",
            "ALS2CR11",
            "AGFG2",
            "AC005306",
            "BAALCOS",
            "ANAPC5",
            "AK096592",
            "ANKRD20A1",
            "ARL16",
            "AC069277",
            "ASB3",
            "CLGN",
            "ANKRD16",
            "AA06",
            "ANAPC16",
            "AFAP1",
            "ADAMTSL1",
            "AJ011981",
            "ACVR1",
            "AC002064",
            "AK097836",
            "AHCYL2",
            "ADAM32",
            "ACACA",
            "AGPAT6",
            "ANKRD9",
            "AC145343",
            "ATP6V1G2",
            "AMER1",
            "AF279780",
            "AOX1",
            "ABHD11",
            "AX747405",
            "BCS1L",
            "ADAM19",
            "ALDH1A3",
            "AHCY",
            "AHNAK",
            "ARMC2",
            "CCNT2-AS1",
            "ACTR5",
            "ALPP",
            "AGRP",
            "ASPSCR1",
            "AC016831",
            "AP2B1",
            "ACOT12",
            "ADIPOQ",
            "BC035400",
            "AC007365",
            "BCAS3",
            "AP000462",
            "ABHD17C",
            "AF086125",
            "ABHD14B",
            "ARSK",
            "ABL1",
            "CASZ1",
            "ARID1B",
            "ADI1",
            "AC008753",
            "DAB1-AS1",
            "AF075036",
            "AKAP12",
            "AP3B2",
            "ADAMTS9-",
            "ANKRD52",
            "APOH",
            "B3GNT9",
            "AREL1",
            "ACOT13",
            "ADRB3",
            "C20orf96",
            "AK311120",
            "ADPRH",
            "ABCA4",
            "ATF7",
            "APOC2",
            "CTC-471F3",
            "ACKR4",
            "AP1S1",
            "ATP7B",
            "AK093256",
            "AMFR",
            "ACY3",
            "ACSF3",
            "AMELX",
            "ADIPOR2",
            "AX746830",
            "AK128734",
            "DYDC2",
            "LRRC31",
            "ADAM20",
            "BC037494",
            "ACBD5",
            "AK9",
            "AL833181",
            "AFF2",
            "ABHD12",
            "CEACAM21",
            "ADCY5",
            "AL022344",
            "AHSP",
            "AGR3",
            "BAGE",
            "ALG5",
            "AX747031",
            "AQP4",
            "ACTN1",
            "ADAMTS8",
            "AC141928",
            "AC010524",
            "ACE",
            "BC022568",
            "ATG2A",
            "AP001062",
            "ARL11",
            "AK1",
            "ARPIN",
            "ABHD17B",
            "BMPER",
            "ACKR1",
            "AC017104",
            "ALX1",
            "CPT1A",
            "CLCA4",
            "CEND1",
            "ASIC3",
            "ARMC5",
            "ACADSB",
            "ANKRD53",
            "AKAP17A",
            "CAND2",
            "AC006538",
            "BCO2",
            "BRICD5",
            "AC091633",
            "BTN3A2",
            "AC018755",
            "ACP1",
            "BCL2L13",
            "AP000473",
            "AK024242",
            "CCDC138",
            "ASXL3",
            "BMS1P6",
            "AC010980",
            "CHRM1",
            "ACTA2",
            "AGA",
            "CD109",
            "BSPRY",
            "BC033241",
            "CCL7",
            "ATP6V1G3",
            "C10orf55",
            "BPHL",
            "AP4S1",
            "RP11-483C6",
            "AL832909",
            "CNRIP1",
            "AC104667",
            "AGAP6",
            "CDC42",
            "ALOX15B",
            "ASGR2",
            "ABCG1",
            "ARMC4",
            "APOA1-AS",
            "DHX35",
            "TTC26",
            "AC007362",
            "ANXA10",
            "ANKRD35",
            "ADAM8",
            "ADIPOR1",
            "AIPL1",
            "C15orf48",
            "AQP3",
            "APBB3",
            "BC039673",
            "AP001063",
            "ABLIM2",
            "CES1",
            "AMD1",
            "BCL9",
            "CABP7",
            "CCDC144CP",
            "BTNL8",
            "APLP1",
            "AMPD1",
            "C7orf49",
            "AC079741",
            "AMIGO2",
            "BC069782",
            "ANO5",
            "BC012193",
            "AKAP7",
            "PMCH",
            "ABHD2",
            "CFH",
            "ALLC",
            "AJAP1",
            "CHGB",
            "AK023507",
            "AHNAK2",
            "STOML3",
            "DDIT4",
            "AEBP1",
            "ACTG2",
            "ACTRT2",
            "ANKRD18A",
            "AKR1C2",
            "CD8A",
            "ALOX12P2",
            "ACTL8",
            "BTK",
            "C12orf77",
            "ENTPD4",
            "ADAM3B",
            "ALG6",
            "GALM",
            "ANKRD46",
            "ABHD15",
            "CCL4",
            "ATP2A2",
            "CCRN4L",
            "AGAP10",
            "ARID5A",
            "AFMID",
            "AMN1",
            "ATP8B5P",
            "BC047626",
            "AKR7A3",
            "ARMC3",
            "BOLA1",
            "ADCY3",
            "ATRNL1",
            "ACSS2",
            "AL022341",
            "COX6CP1",
            "BAG3",
            "BRD9",
            "ACTB",
            "ACACB",
            "C17orf99",
            "ACOX2",
            "C20orf195",
            "ACRC",
            "CNDP2",
            "AADACP1",
            "CTLA4",
            "CHN1",
            "AOC1",
            "ADAMTS19",
            "C21orf59",
            "AIFM3",
            "BC043291",
            "AX747639",
            "AC128677",
            "GRID1-AS1",
            "OLFM1",
            "ADAM30",
            "SIGLEC17P",
            "AK3",
            "CGN",
            "ALG11",
            "AGAP1",
            "C4orf45",
            "ANGPTL7",
            "AC083949",
            "AKAP1",
            "ATF6",
            "C18orf61",
            "CCL15",
            "ANXA2P1",
            "ACTBP9",
            "AGAP4",
            "AK057978",
            "ARHGEF34P",
            "AMER2",
            "BC041363",
            "CNTN3",
            "ABCB1",
            "AP000696",
            "SPDYA",
            "ANKRD30A",
            "AK097453",
            "CNTFR",
            "AC073321",
            "COG1",
            "SETD7",
            "ACVR2A",
            "F2R",
            "BDKRB1",
            "ANXA5",
            "ANKMY1",
            "ADH1C",
            "AX747652",
            "GEM",
            "ACTL10",
            "SCIMP",
            "ANAPC10",
            "ARHGAP35",
            "BCL2",
            "ACP2",
            "ACTC1",
            "KRTAP3-3",
            "DNAJC28",
            "B4GALT3",
            "ADAMTS15",
            "CPXCR1",
            "DAG1",
            "CMTM3",
            "CCDC79",
            "AKAP4",
            "C2orf40",
            "CLCN4",
            "BC150507",
            "APOL1",
            "AK023627",
            "BC045559",
            "AK024134",
            "BC048420",
            "ANKRA2",
            "FAM24A",
            "RNF157-AS1",
            "ADNP2",
            "ANGPT1",
            "ITGA1",
            "C2CD4A",
            "AC007255",
            "ANP32A",
            "MLLT4-AS1",
            "KLRC3",
            "BC039485",
            "APOBR",
            "AY940074",
            "RP11-112L7",
            "AX746823",
            "AP4E1",
            "ARF5",
            "CTSZ",
            "C1orf116",
            "AVL9",
            "BEND7",
            "ASZ1",
            "AC099684",
            "ARHGEF3",
            "AGBL4",
            "CLEC4C",
            "ADM2",
            "CTD-2639E6",
            "ASNS",
            "AKAP10",
            "ATP7A",
            "COL18A1",
            "AK6",
            "COL5A3",
            "C2orf50",
            "APOLD1",
            "RPEL1",
            "ARPC5",
            "DNM3",
            "MS4A12",
            "AL928742",
            "ZNF280A",
            "AK021804",
            "CLIC5",
            "B3GALT6",
            "CFD",
            "IBA57-AS1",
            "ACTN4",
            "BC022892",
            "CPED1",
            "AVPI1",
            "C8orf17",
            "ADAMTSL5",
            "AK021537",
            "ADCY2",
            "CCDC9",
            "ASIC1",
            "ZNF607",
            "ASPHD2",
            "KCTD14",
            "NAAA",
            "SLC27A2",
            "AFF1",
            "ACSS3",
            "IGHV7-81",
            "CLIC4",
            "ATG4A",
            "BAAT",
            "BC034636",
            "NECAB1",
            "AKR1C3",
            "F2RL3",
            "ZKSCAN2",
            "ACSM2A",
            "ECM1",
            "CD8B",
            "MIR133A1HG",
            "AX747444",
            "KRT77",
            "BNIP1",
            "BC048141",
            "SPIC",
            "C11orf21",
            "C12orf79",
            "GLB1L3",
            "C9orf47",
            "ARHGEF9",
            "PAQR4",
            "C8orf49",
            "C1orf54",
            "PHACTR3",
            "KCNAB1",
            "IL17A",
            "ALDOB",
            "ATP5B",
            "IMPG1",
            "ATP8A1",
            "AC068831",
            "OLFM3",
            "ACAT2",
            "CDY1B",
            "ANK3",
            "ACADS",
            "AKAP8L",
            "ACSM5",
            "TAS2R3",
            "CCDC94",
            "AP4B1",
            "AGO1",
            "BCL9L",
            "GCC2",
            "B476C20",
            "OR2C3",
            "C1orf111",
            "BBS12",
            "CNNM4",
            "ARSB",
            "RP5-944M2",
            "AX747730",
            "CST9L",
            "GTPBP10",
            "ADCY4",
            "CACNA2D4",
            "ADAMTS7",
            "OPN1SW",
            "APOBEC3B",
            "CHST4",
            "AL832615",
            "C1orf21",
            "ARAP1",
            "HBG1",
            "ARRDC3",
            "DNAJB12",
            "ANKRD44",
            "AP001630",
            "ANKRD13D",
            "AHRR",
            "BRPF3",
            "TBC1D7",
            "CCNB1",
            "APBA1",
            "BRE-AS1",
            "GPR37",
            "CLEC12B",
            "CCDC110",
            "ART3",
            "FST",
            "ACTR3",
            "AF131215",
            "AGAP5",
            "ACAT1",
            "CDK5RAP2",
            "AURKB",
            "ASIC2",
            "ABCD3",
            "ARID4B",
            "RP11-252E2",
            "AMOTL2",
            "C16orf46",
            "AV4S1",
            "ACAD8",
            "ACSM2B",
            "ACBD4",
            "PODXL",
            "PFKP",
            "ARL10",
            "APCS",
            "CLASP1",
            "C9orf156",
            "ANXA2R",
            "CHCHD10",
            "HEXDC",
            "AIF1L",
            "CECR5",
            "ADH7",
            "AKT1",
            "C10orf2",
            "ICMT",
            "BPIFA2",
            "ACTR3BP5",
            "AKAP9",
            "ANKRD13B",
            "ALG14",
            "AKIRIN1",
            "CYP4F12",
            "BC045791",
            "BC024169",
            "KCNB2",
            "CC2D2A",
            "BOLA2B",
            "CDH9",
            "AXIN2",
            "C5orf51",
            "CYTL1",
            "NBPF3",
            "FBXL21",
            "APBB1IP",
            "ADAMTS17",
            "ANKEF1",
            "MKNK1-AS1",
            "APOA1",
            "AGTR2",
            "MAP3K7CL",
            "ANKRD13C",
            "ASB9",
            "CTC-471C19",
            "BC038570",
            "TUBB2A",
            "BHLHE40",
            "AKR1D1",
            "ATHL1",
            "BC047651",
            "ASCL3",
            "AS3MT",
            "C11orf63",
            "ACAD11",
            "ANKMY2",
            "ANKRD34A",
            "ABHD5",
            "ALMS1P",
            "ARHGEF10L",
            "PROX1-AS1",
            "AFG3L2",
            "CTC-384G19",
            "ADTRP",
            "MAGI2-IT1",
            "IRAK2",
            "AC078883",
            "CASC10",
            "COX6CP2",
            "CALN1",
            "ACAN",
            "AFAP1L2",
            "RSPO3",
            "CH25H",
            "AK000798",
            "CCDC38",
            "ARL2",
            "ARL8A",
            "CD244",
            "ABRACL",
            "ANO1",
            "ETNPPL",
            "ANGPT2",
            "PTPRB",
            "ARHGAP4",
            "ACTR6",
            "ANKRD10",
            "DUXAP10",
            "SMIM12",
            "PDC",
            "MPPED2",
            "LRRC19",
            "RP11-10K16",
            "CARD6",
            "AC078842",
            "COPS7B",
            "ATP6V0E2-",
            "ARFGAP2",
            "APOA2",
            "RP11-644F5",
            "PTGES3L",
            "CTB-50L17",
            "PLCG1-AS1",
            "C6",
            "AK094915",
            "POMGNT1",
            "BC047364",
            "ACBD3",
            "CMTM4",
            "DQ570096",
            "RMDN3",
            "CAD",
            "ARMCX6",
            "ENDOU",
            "BC038194",
            "NDUFC2-",
            "FITM2",
            "BC031255",
            "ARSJ",
            "AK055458",
            "GCM2",
            "ARID3B",
            "CARS2",
            "BC041003",
            "APLP2",
            "AX747517",
            "AP006216",
            "ATP10D",
            "ARL13B",
            "CEP72",
            "ATXN7L3B",
            "C1orf61",
            "OR2I1P",
            "AJ606316",
            "BC079832",
            "CLEC3A",
            "FUT7",
            "ADSL",
            "C19orf33",
            "ANO2",
            "AK093356",
            "CNTNAP3P2",
            "NTPCR",
            "C10orf67",
            "CDYL2",
            "AQP9",
            "TADA2A",
            "HMOX1",
            "ENTPD7",
            "CA2",
            "ABCC6P2",
            "ERMAP",
            "LMO2",
            "AY927499",
            "C20orf196",
            "IL21",
            "FGFBP2",
            "EIF4G2",
            "MIR4435-",
            "AL109706",
            "HERC2",
            "AX747750",
            "AURKC",
            "CASC17",
            "AFF4",
            "ARL9",
            "DDT",
            "FAM92A1",
            "CYP2B7P",
            "BC016361",
            "C11orf45",
            "IRGQ",
            "ANGEL1",
            "ATP6V0A2",
            "CLEC4F",
            "SIGLECL1",
            "EPT1",
            "HIST1H2AK",
            "CREB3L4",
            "CXCL8",
            "SERPINB9P1",
            "ARL15",
            "C18orf15",
            "ARSI",
            "ARHGAP24",
            "SCGB2A1",
            "APPBP2",
            "CRIPAK",
            "C16orf89",
            "DCHS2",
            "PCNAP3",
            "TOLLIP-AS1",
            "COLGALT2",
            "C11orf87",
            "ANAPC2",
            "PLEK",
            "AP001347",
            "ASTN1",
            "ARL6IP6",
            "ACAP3",
            "AX748267",
            "CBR1",
            "CALCRL",
            "ZIM3",
            "ATP9A",
            "BC032026",
            "DIAPH2-AS1",
            "C4orf36",
            "ANKS1B",
            "SLC25A4",
            "MRPS27",
            "BC041947",
            "LGALS4",
            "AC005162",
            "BRK1",
            "CLEC7A",
            "RALY-AS1",
            "C11orf92",
            "EPN2-AS1",
            "SPHK1",
            "PGAM2",
            "VSIG10",
            "CLRN1",
            "RHOF",
            "CRAMP1L",
            "ZSCAN25",
            "AK055910",
            "BC042382",
            "BAD",
            "C19orf73",
            "AX747507",
            "MIR137",
            "CCDC148-",
            "AC092620",
            "SCGB3A2",
            "ABCD2",
            "AAMDC",
            "SSMEM1",
            "ASB8",
            "BC039319",
            "BC045560",
            "CSTB",
            "AOC3",
            "ALOX5",
            "CYP2C8",
            "TMLHE",
            "ADAM21",
            "CREB5",
            "FAM163A",
            "TLR8-AS1",
            "ASPHD1",
            "PKHD1L1",
            "AXL",
            "AF070581",
            "APCDD1L",
            "APOPT1",
            "TMCC1-AS1",
            "CCL3",
            "ANKRD20A2",
            "HBG2",
            "DDTL",
            "MIR137HG",
            "ANKRD20A3",
            "ANKRD20A4",
            "CCL3L3",
            "CCL3L1"
        ],
        "Coefficient": [
            -0.11458230630546068,
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            -0.04213899186364215,
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            -0.03396672196632401,
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            -0.03154679075913347,
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