{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "B3GAT1",
            "C1R",
            "BCAP31",
            "C4BPA",
            "BTK",
            "CD40LG",
            "C1QB",
            "CCL8",
            "APP",
            "CXCR3",
            "DEFB4A",
            "BCL2",
            "EBI3",
            "HLA-DQA1",
            "LILRB5",
            "IRAK2",
            "CCL15",
            "MAPK14",
            "CD59",
            "FADD",
            "C3",
            "HFE",
            "TP53",
            "TLR3",
            "BATF",
            "ADGRE2",
            "EGR2",
            "IL1R1",
            "HRAS",
            "CXCR2",
            "LTB4R",
            "CD9",
            "CD86",
            "DEFB103A",
            "FKBP5",
            "CD53",
            "PTGS2",
            "CCL20",
            "CIITA",
            "BST2",
            "CR2",
            "ATG16L1",
            "CCL3",
            "BCL3",
            "IL7",
            "PSMB5",
            "FYN",
            "PTAFR",
            "CARD9",
            "CTNNB1",
            "NFATC2",
            "CCR8",
            "DEFB103B",
            "CRADD",
            "IL4R",
            "S1PR1",
            "CCND3",
            "FCAR",
            "CCL5",
            "KLRC3",
            "IKZF1",
            "ACKR4",
            "IL17A",
            "MBP",
            "POLR1G",
            "NT5E",
            "CCL22",
            "FN1",
            "IL6",
            "CCL2",
            "CCRL2",
            "CD46",
            "IRGM",
            "FAS",
            "CD14",
            "AIRE",
            "MALT1",
            "CFI",
            "IRF7",
            "ABL1",
            "ATG7",
            "CCL13",
            "KLRA1P",
            "IGF2R",
            "MAPKAPK2",
            "FOXP3",
            "ATG10",
            "CD79B",
            "LTB4R2",
            "TNFSF11",
            "LCP2",
            "CD160",
            "SLC2A1",
            "CFH",
            "CD80",
            "ATG12",
            "CXCL11",
            "FCGR2B",
            "CD19",
            "NOTCH2",
            "MUC1",
            "HLA-DRB3",
            "CCL19",
            "PSMC2",
            "RAG2",
            "ITGA5",
            "DEFB1",
            "SPP1",
            "IL22",
            "FCER1A",
            "SELE",
            "CD36",
            "LIF",
            "IL10",
            "CFD",
            "NOD2",
            "PDCD1",
            "IL1RAP",
            "NLRP3",
            "MAP4K4",
            "SELPLG",
            "EGR1",
            "ZBTB16",
            "MX1",
            "IL16",
            "CD7",
            "IL4",
            "CD274",
            "BLNK",
            "EDNRB",
            "IL32",
            "IL13RA1",
            "CD1D",
            "CFB",
            "GZMK",
            "IFI16",
            "TNFSF15",
            "IL21R",
            "TIRAP",
            "CSF2",
            "IL1B",
            "IL26",
            "BAX",
            "CUL9",
            "BCL10",
            "CD4",
            "CCL16",
            "IL21",
            "GP1BB",
            "CCR1",
            "CLEC6A",
            "IL1RN",
            "TCF7",
            "TLR4",
            "TNFSF8",
            "PDCD2",
            "MSR1",
            "CD48",
            "IL7R",
            "SLAMF6",
            "POU2F2",
            "AICDA",
            "STAT4",
            "TNFRSF17",
            "CLEC5A",
            "ITGA4",
            "CD1A",
            "TNFSF13B",
            "ITLN2",
            "IRF3",
            "IL2RA",
            "CXCL8",
            "SLAMF1",
            "RAG1",
            "ITGA2B",
            "KCNJ2",
            "TGFBI",
            "CD70",
            "BTLA",
            "CCR2",
            "C5",
            "CLU",
            "ITGB1",
            "KLRG1",
            "TOLLIP",
            "TAPBP",
            "B2M",
            "IL3",
            "ADA",
            "IRF5",
            "CASP10",
            "IRAK1",
            "IFI35",
            "MAPK11",
            "HLA-DMB",
            "UBE2L3",
            "CD58",
            "MME",
            "LCK",
            "CCR6",
            "CD164",
            "CCL4",
            "CD163",
            "KLRG2",
            "TRAF1",
            "CCL26",
            "IFNA2",
            "PSMB7",
            "HAVCR2",
            "MIF",
            "PAX5",
            "PRKCD",
            "IRF4",
            "CTSC",
            "IL12B",
            "TLR1",
            "NCAM1",
            "PDCD1LG2",
            "IL6R",
            "TNFRSF10C",
            "CD8B",
            "PTPN2",
            "CXCL1",
            "TRAF4",
            "IRAK4",
            "ARHGDIB",
            "IL10RA",
            "CD96",
            "PML",
            "HLA-C",
            "CLEC4E",
            "CD28",
            "ICAM1",
            "TLR9",
            "CX3CR1",
            "CD34",
            "IFNL1",
            "CD276",
            "PLA2G2E",
            "CCR10",
            "ENTPD1",
            "CXCR6",
            "MYD88",
            "TAGAP",
            "IKBKE",
            "CCL23",
            "MS4A1",
            "ITGAL",
            "ITGB2",
            "CASP8",
            "CD99",
            "PDGFB",
            "IL2RG",
            "IL27",
            "TCF4",
            "CDKN1A",
            "CD8A",
            "IL15",
            "TNFSF12",
            "IFIH1",
            "BST1",
            "CXCL12",
            "KLRB1",
            "IL6ST",
            "CR1",
            "TLR2",
            "PLAU",
            "NFATC1",
            "C1QA",
            "STAT1",
            "KLRC1",
            "C6",
            "RELB",
            "STAT5A",
            "HLA-DPA1",
            "CSF1",
            "CXCL2",
            "IFNAR1",
            "ICAM3",
            "STAT3",
            "CSF2RB",
            "CEACAM6",
            "CD74",
            "TNFRSF9",
            "CCL11",
            "XCL1",
            "PTGER4",
            "IKBKB",
            "IFNB1",
            "NOTCH1",
            "CCR5",
            "TGFBR1",
            "MRC1",
            "BID",
            "SYK",
            "PRDM1",
            "LILRB2",
            "C1QBP",
            "ITGAM",
            "VCAM1",
            "CD81",
            "S100A8",
            "NFKBIZ",
            "IL17F",
            "SMAD5",
            "ARG1",
            "ELP1",
            "HAMP",
            "MR1",
            "TLR5",
            "C7",
            "LAIR1",
            "TRAF6",
            "CD3D",
            "TLR8",
            "CD40",
            "XCR1",
            "GATA3",
            "FCGRT",
            "IL18",
            "KIR3DL1",
            "MAF",
            "NOD1",
            "HLA-A",
            "PSMD7",
            "FCGR2A",
            "ARG2",
            "AHR",
            "PDGFRB",
            "IL2RB",
            "CD2",
            "BCL6",
            "RTRAF",
            "LAG3",
            "CCL18",
            "IL20",
            "IRAK3",
            "CD24",
            "IL5",
            "LITAF",
            "NFKB2",
            "PLAUR",
            "SOCS3",
            "CEBPB",
            "LTA",
            "TFRC",
            "TBK1",
            "C1S",
            "PRF1",
            "CD55",
            "GBP5",
            "TNFRSF13B",
            "IL23R",
            "SERPING1",
            "GPI",
            "HLA-DPB1",
            "THY1",
            "LILRA1",
            "NCF4",
            "KIT",
            "IL1RL2",
            "CASP2",
            "TNFRSF11A",
            "JAK3",
            "LY96",
            "TNFRSF1B",
            "TYK2",
            "KLRF1",
            "GBP1",
            "LILRB1",
            "ITGA6",
            "TNFSF4",
            "NOS2",
            "LILRA6",
            "IL12A",
            "STAT6",
            "ITGAE",
            "LAMP3",
            "ICOS",
            "IFNL2",
            "CD6",
            "CD83",
            "IL11RA",
            "HLA-DOB",
            "TGFBR2",
            "TAP2",
            "IFIT2",
            "CD27",
            "CHUK",
            "CD79A",
            "ABCB1",
            "PTPN6",
            "CX3CL1",
            "KIR3DL3",
            "CSF3R",
            "TNFRSF8",
            "CLEC7A",
            "HLA-DRB1",
            "MASP1",
            "PLAAT4",
            "ICOSLG",
            "TNF",
            "CMKLR1",
            "IL9",
            "CD247",
            "CXCL13",
            "CCL7",
            "ILF3",
            "C9",
            "PIGR",
            "PPARG",
            "TNFRSF14",
            "CYBB",
            "MAPK1",
            "IL18RAP",
            "CD5",
            "HLA-B",
            "HLA-DMA",
            "ICAM5",
            "SOCS1",
            "PTPN22",
            "PSMB9",
            "IKZF2",
            "RUNX1",
            "IRF8",
            "CEACAM8",
            "CD82",
            "TIGIT",
            "IKZF3",
            "NCR1",
            "LTF",
            "TRAF3",
            "XBP1",
            "DUSP4",
            "CD244",
            "LILRA3",
            "IFNGR1",
            "CEACAM1",
            "CD44",
            "IDO1",
            "CDH5",
            "HLA-DQB1",
            "MASP2",
            "SLAMF7",
            "LTBR",
            "LGALS3",
            "JAK1",
            "ZEB1",
            "CXCR1",
            "ICAM2",
            "ITGAX",
            "GZMB",
            "CASP3",
            "STAT5B",
            "LEF1",
            "RAF1",
            "LILRB3",
            "IL19",
            "KLRC4",
            "C8A",
            "IFNG",
            "CFP",
            "IRF1",
            "CISH",
            "RORC",
            "TICAM1",
            "TRAF2",
            "CD22",
            "HLA-DRA",
            "DPP4",
            "LILRA2",
            "IL1A",
            "PTK2",
            "TAL1",
            "CASP1",
            "TNFSF10",
            "CLEC4A",
            "CTSG",
            "IL1R2",
            "LILRA5",
            "IL13",
            "KLRD1",
            "VTN",
            "GZMA",
            "CSF1R",
            "NFATC3",
            "MBL2",
            "IL17B",
            "SRC",
            "KIR3DL2",
            "IL18R1",
            "NFIL3",
            "RELA",
            "ATM",
            "MAP4K1",
            "CXCR4",
            "C2",
            "ICAM4",
            "KLRC2",
            "TNFAIP6",
            "SKI",
            "C8G",
            "IL12RB1",
            "CCL24",
            "IFITM1",
            "PPBP",
            "KLRK1",
            "IL22RA2",
            "FCER1G",
            "GNLY",
            "C8B",
            "IL2",
            "MARCO",
            "GFI1",
            "SH2D1A",
            "IL23A",
            "TNFAIP3",
            "TAP1",
            "LILRB4",
            "EOMES",
            "CXCL10",
            "CTSS",
            "TRAF5",
            "S100A9",
            "MCL1",
            "JAK2",
            "CXCL9",
            "LILRA4",
            "TNFRSF13C",
            "SELL",
            "CCR7",
            "PSMB10",
            "SMAD3",
            "IFNAR2",
            "ITLN1",
            "NFKBIA",
            "CAMP",
            "CD3E",
            "STING1",
            "IKBKG",
            "PSMB8",
            "NFKB1",
            "PLA2G2A",
            "PECAM1",
            "CD209",
            "GPR183",
            "TLR7",
            "MAP4K2",
            "IL1RL1",
            "ETS1",
            "TNFRSF4",
            "TBX21",
            "ZAP70",
            "KLRF2",
            "TGFB1",
            "SIGIRR",
            "PYCARD",
            "STAT2"
        ],
        "Coefficient": [
            0.11788318963087428,
            -0.0868284798323133,
            0.08068493769241065,
            0.07683325041568768,
            0.07579829387686546,
            0.07513783797532571,
            -0.07183968396674802,
            -0.07145473856597649,
            0.06915755328156363,
            0.06826705619524157,
            -0.06726365520255086,
            0.06639996506291701,
            0.06509504387535361,
            -0.0642982134192648,
            0.0639492195021737,
            0.061842673042182085,
            0.06180234355176287,
            -0.061570706927820844,
            -0.0607131563666952,
            0.06008530010636142,
            -0.05992325778887338,
            -0.05903961767152301,
            -0.05882352007420981,
            0.057150676807280885,
            -0.056791324813683854,
            -0.05562522869808358,
            0.05532575315789723,
            0.055251811268554836,
            -0.055002443680611815,
            -0.05473352313811196,
            0.05450776695783569,
            0.053266037540602405,
            0.05305378374227811,
            0.052701283022249544,
            -0.052437066188290256,
            -0.05187482861339485,
            0.051585351013795265,
            -0.05079040020103434,
            0.05063296973682061,
            0.050519700321595466,
            -0.050437747761046196,
            0.04940055205134223,
            0.04891363676600713,
            0.04859665481373109,
            -0.048183225421073284,
            -0.047856512137691334,
            -0.04713723052659344,
            -0.045540810456607274,
            0.04537730116137013,
            0.04537023097665308,
            0.04502948179603571,
            -0.044775056056802244,
            -0.04466556521939594,
            -0.044453611707111394,
            0.04435851711125366,
            0.04435790086627612,
            -0.04362211924641441,
            0.04337305585310507,
            -0.04295959339002668,
            0.04279204138828694,
            -0.042692176278838374,
            0.04253531219332673,
            0.04234878092802984,
            -0.04098570021122157,
            0.03943715424810518,
            -0.039416550002069,
            -0.039326352916369565,
            0.03930438656709525,
            0.03906020597715366,
            0.03875387267262887,
            0.03868840257074225,
            0.03847722330836647,
            0.03824756031776232,
            0.03819293666407966,
            -0.03800331934228561,
            0.037864080966911524,
            0.03768977048612786,
            0.03754803148504648,
            -0.037495018733168274,
            -0.037420659588128034,
            0.037352796105034856,
            0.037331429261448834,
            -0.03714277666503323,
            0.036782493170588605,
            -0.036778404296374655,
            0.03656499355938629,
            -0.036417535117717274,
            0.03624099293115225,
            -0.03618213258397316,
            0.035838181394526256,
            -0.0358336865772757,
            0.035816072102992695,
            -0.035792682889592566,
            -0.03559849249771499,
            0.03489344733475257,
            0.034658587850605584,
            0.03463721241029143,
            -0.0342843814286386,
            0.034183233194558085,
            -0.03414138434552929,
            -0.033981390512313296,
            0.03388338701805844,
            0.03382944886887962,
            -0.033611851158370024,
            -0.033298515602862414,
            0.03329555679952664,
            -0.03314642526934913,
            -0.03302617792428502,
            0.032678273263786306,
            -0.032588087932633986,
            0.03247788408702869,
            0.03222991496126234,
            -0.03194785409872898,
            -0.03184530815342943,
            -0.03183313554116338,
            0.03175129796348574,
            -0.03155671085108858,
            0.03140996352809846,
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            0.031251130490870166,
            -0.031089006976963728,
            -0.031014661499396568,
            0.030772803860484615,
            0.03043059161251547,
            0.03008207457684195,
            -0.030040509465603115,
            0.029732301768031467,
            0.02944814900400352,
            -0.029245903520655276,
            0.029137325993473715,
            -0.02874536133063542,
            0.028629599950384336,
            0.028301914294755592,
            0.028187695043971367,
            0.02780759269560364,
            0.027761968392263442,
            -0.02768067754005124,
            -0.02749777379783698,
            0.027469226925121874,
            0.027403151338367432,
            0.027386971959207296,
            -0.02737451459354991,
            0.02735654421622384,
            -0.027341834137429015,
            -0.027161246792656527,
            0.027121106216020024,
            0.02699461734633606,
            -0.026967734696661295,
            -0.026945657101333502,
            -0.02649993933988445,
            -0.026221903341022215,
            -0.026179619987609717,
            0.026085741807781972,
            -0.02600095855218167,
            0.02585525325994554,
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            -0.025719313473764528,
            0.025674741421674262,
            -0.025660717155165342,
            -0.025639081005018088,
            -0.025623543278741875,
            -0.025547116456647923,
            0.025528421912161946,
            -0.025489103584110925,
            -0.025327067929649588,
            -0.025253486452810146,
            0.025252326657223913,
            -0.025140036057831123,
            -0.025075222604071894,
            -0.025027877779558602,
            -0.025006622697936708,
            -0.02472847057618302,
            0.02451931345246111,
            -0.024466275206847254,
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            0.024375627464899494,
            0.024356263822301525,
            -0.024302715612422816,
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            -0.023976421483814014,
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            -0.023467155299348907,
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            0.02344837310397737,
            -0.023288912121938093,
            -0.02327734998783268,
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            0.018966054684966347,
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            -0.018203391651712707,
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            -0.01805723967828975,
            0.01805712080885893,
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