{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "C1R",
            "B3GAT1",
            "C4BPA",
            "BCAP31",
            "BTK",
            "C1QB",
            "CD40LG",
            "DEFB4A",
            "CXCR3",
            "CCL8",
            "IRAK2",
            "APP",
            "HLA-DQA1",
            "EBI3",
            "LILRB5",
            "MAPK14",
            "BATF",
            "BCL2",
            "CCL15",
            "C3",
            "TP53",
            "EGR2",
            "TLR3",
            "FADD",
            "HRAS",
            "IL1R1",
            "ADGRE2",
            "HFE",
            "CD9",
            "LTB4R",
            "CIITA",
            "CD59",
            "CD86",
            "FKBP5",
            "CXCR2",
            "DEFB103A",
            "PTGS2",
            "CR2",
            "BST2",
            "CCL3",
            "CCL20",
            "CD53",
            "CCND3",
            "ATG16L1",
            "PSMB5",
            "FYN",
            "CTNNB1",
            "PTAFR",
            "IL7",
            "CARD9",
            "DEFB103B",
            "IL4R",
            "BCL3",
            "SLC2A1",
            "NFATC2",
            "S1PR1",
            "IKZF1",
            "FCAR",
            "MBP",
            "POLR1G",
            "KLRC3",
            "CCR8",
            "CRADD",
            "CCL5",
            "IGF2R",
            "MAPKAPK2",
            "NT5E",
            "FN1",
            "IRGM",
            "ATG12",
            "CD14",
            "MALT1",
            "IL6",
            "CCL22",
            "CFH",
            "CD160",
            "TNFSF11",
            "IL17A",
            "IRF7",
            "FAS",
            "ACKR4",
            "LTB4R2",
            "AIRE",
            "FOXP3",
            "CFI",
            "CD79B",
            "CXCL11",
            "CD80",
            "LCP2",
            "ABL1",
            "CD46",
            "CCL2",
            "CCRL2",
            "KLRA1P",
            "CCL13",
            "NOTCH2",
            "CD19",
            "ITGA5",
            "SPP1",
            "FCER1A",
            "RAG2",
            "HLA-DRB3",
            "CFD",
            "MUC1",
            "LIF",
            "DEFB1",
            "IL22",
            "ATG10",
            "CD36",
            "PSMC2",
            "SELE",
            "NOD2",
            "NLRP3",
            "FCGR2B",
            "SELPLG",
            "ZBTB16",
            "IL13RA1",
            "IL1RAP",
            "PDCD1",
            "MAP4K4",
            "CCL19",
            "MX1",
            "ATG7",
            "EGR1",
            "IL4",
            "IL16",
            "IL21R",
            "IL32",
            "EDNRB",
            "GZMK",
            "IL10",
            "BTLA",
            "CFB",
            "BLNK",
            "IL1B",
            "GP1BB",
            "IL21",
            "SLAMF6",
            "CD4",
            "POU2F2",
            "STAT4",
            "TNFSF15",
            "MSR1",
            "TLR4",
            "IL1RN",
            "TOLLIP",
            "CSF2",
            "CD274",
            "TIRAP",
            "CUL9",
            "BCL10",
            "ITLN2",
            "ITGA2B",
            "IL26",
            "CLEC5A",
            "IL7R",
            "PDCD2",
            "CD7",
            "KCNJ2",
            "IFI16",
            "CD1D",
            "TCF7",
            "CD48",
            "ITGB1",
            "TNFSF8",
            "B2M",
            "CD1A",
            "TNFSF13B",
            "IRF3",
            "CCL16",
            "ITGA4",
            "BAX",
            "IL2RA",
            "SLAMF1",
            "KLRG1",
            "IRF5",
            "CLEC6A",
            "CXCL8",
            "TGFBI",
            "CLU",
            "TNFRSF17",
            "CASP8",
            "IFI35",
            "PDCD1LG2",
            "MME",
            "MAPK11",
            "CD70",
            "IL3",
            "RAG1",
            "CXCL1",
            "CCL4",
            "CTSC",
            "CCR6",
            "CCR1",
            "CX3CR1",
            "TAPBP",
            "IRF4",
            "CD163",
            "HLA-DMB",
            "C5",
            "CCR10",
            "PRKCD",
            "UBE2L3",
            "AICDA",
            "LCK",
            "PAX5",
            "IRAK1",
            "CCR2",
            "TRAF1",
            "IFNA2",
            "HLA-C",
            "HAVCR2",
            "CD8B",
            "TAGAP",
            "TLR1",
            "IRAK4",
            "CCL26",
            "IL12B",
            "ARHGDIB",
            "TNFRSF10C",
            "ENTPD1",
            "CASP10",
            "MS4A1",
            "MIF",
            "PTPN2",
            "CXCR6",
            "PSMB7",
            "IL15",
            "TCF4",
            "KLRG2",
            "CD58",
            "NCAM1",
            "CLEC4E",
            "IL6R",
            "CD96",
            "IKBKE",
            "IFNL1",
            "MYD88",
            "C1QA",
            "IL10RA",
            "ITGAL",
            "CCL23",
            "ITGB2",
            "STAT1",
            "ICAM1",
            "CD8A",
            "CDKN1A",
            "CD276",
            "TRAF4",
            "ICAM3",
            "STAT3",
            "IL2RG",
            "PML",
            "PLA2G2E",
            "CD164",
            "TLR9",
            "TNFSF12",
            "TLR2",
            "IL27",
            "CD28",
            "RELB",
            "ADA",
            "PDGFB",
            "HLA-DPA1",
            "NFATC1",
            "STAT5A",
            "IFNAR1",
            "CSF1",
            "PLAU",
            "CSF2RB",
            "CD34",
            "XCL1",
            "IFNB1",
            "PTGER4",
            "SYK",
            "IL6ST",
            "CXCL12",
            "CR1",
            "CD81",
            "SMAD5",
            "C6",
            "BST1",
            "TNFRSF9",
            "MRC1",
            "CCL11",
            "IFIH1",
            "CD74",
            "KLRB1",
            "TGFBR1",
            "CEACAM6",
            "CXCL2",
            "TLR5",
            "PRDM1",
            "CD55",
            "ITGAM",
            "CD40",
            "LILRB2",
            "VCAM1",
            "ABCB1",
            "NOTCH1",
            "CD99",
            "CD2",
            "ARG2",
            "IL2RB",
            "KIR3DL1",
            "IL17F",
            "IL20",
            "S100A8",
            "PSMD7",
            "C7",
            "NFKBIZ",
            "KLRC1",
            "IL11RA",
            "CEBPB",
            "FCGRT",
            "PDGFRB",
            "CD3D",
            "IKBKB",
            "PLAUR",
            "CX3CL1",
            "C1S",
            "GATA3",
            "CCR5",
            "IL1RL2",
            "LAIR1",
            "TLR8",
            "TNFRSF1B",
            "HLA-A",
            "XCR1",
            "JAK3",
            "TNFRSF11A",
            "LITAF",
            "HAMP",
            "BCL6",
            "THY1",
            "AHR",
            "FCGR2A",
            "KLRF1",
            "IL5",
            "NCF4",
            "KIT",
            "MR1",
            "IRAK3",
            "ELP1",
            "SOCS3",
            "PRF1",
            "IL18",
            "C1QBP",
            "CCL7",
            "TRAF6",
            "RTRAF",
            "CD83",
            "LTA",
            "HLA-DPB1",
            "TBK1",
            "LILRA6",
            "TNFSF4",
            "LAG3",
            "ICOS",
            "SERPING1",
            "IFNL2",
            "NOD1",
            "GBP1",
            "GPI",
            "TGFBR2",
            "HLA-DOB",
            "BID",
            "C9",
            "LILRA1",
            "TFRC",
            "NFKB2",
            "STAT6",
            "TYK2",
            "GBP5",
            "MAF",
            "IL23R",
            "CCL18",
            "ITGAE",
            "IFIT2",
            "KIR3DL3",
            "ITGA6",
            "CD6",
            "ICOSLG",
            "ICAM5",
            "CYBB",
            "TNFRSF13B",
            "CD24",
            "CSF3R",
            "IL12A",
            "LY96",
            "CMKLR1",
            "CD247",
            "LILRB1",
            "LAMP3",
            "CASP2",
            "NOS2",
            "SOCS1",
            "HLA-DMA",
            "IFNGR1",
            "ATM",
            "CXCL13",
            "MAPK1",
            "HLA-B",
            "IL9",
            "CLEC7A",
            "TNFRSF8",
            "PSMB9",
            "CD244",
            "CEACAM8",
            "CD79A",
            "CD82",
            "PLAAT4",
            "IL18RAP",
            "ILF3",
            "IKZF3",
            "CASP3",
            "CD44",
            "IRF8",
            "TNF",
            "IRF1",
            "RUNX1",
            "HLA-DRB1",
            "TAP2",
            "CD5",
            "TIGIT",
            "TNFRSF14",
            "IKZF2",
            "LILRA3",
            "CHUK",
            "PTPN6",
            "PIGR",
            "NCR1",
            "RAF1",
            "MASP1",
            "RORC",
            "LGALS3",
            "IL13",
            "GZMB",
            "PTPN22",
            "PTK2",
            "JAK1",
            "CD27",
            "HLA-DQB1",
            "LTF",
            "IDO1",
            "CFP",
            "DUSP4",
            "LTBR",
            "MASP2",
            "XBP1",
            "LEF1",
            "GNLY",
            "ARG1",
            "CDH5",
            "TRAF2",
            "TRAF3",
            "STAT5B",
            "C2",
            "SLAMF7",
            "PPARG",
            "KLRC4",
            "ITGAX",
            "IL18R1",
            "HLA-DRA",
            "LILRB3",
            "TNFSF10",
            "DPP4",
            "ICAM4",
            "IL19",
            "LILRA5",
            "KLRC2",
            "CISH",
            "ICAM2",
            "ZEB1",
            "CSF1R",
            "C8A",
            "LILRA2",
            "TAL1",
            "IL1R2",
            "MBL2",
            "SH2D1A",
            "IL12RB1",
            "CLEC4A",
            "VTN",
            "NFATC3",
            "CTSG",
            "GFI1",
            "CXCR4",
            "TICAM1",
            "LILRA4",
            "CASP1",
            "IL1A",
            "KLRD1",
            "TNFAIP3",
            "CEACAM1",
            "TAP1",
            "JAK2",
            "NFIL3",
            "SRC",
            "PPBP",
            "CD22",
            "IL17B",
            "LILRB4",
            "CD209",
            "CXCR1",
            "C8B",
            "IFNG",
            "TNFAIP6",
            "GZMA",
            "KIR3DL2",
            "IFITM1",
            "CXCL10",
            "MAP4K1",
            "CD3E",
            "FCER1G",
            "S100A9",
            "SELL",
            "PLA2G2A",
            "MARCO",
            "KLRK1",
            "IL22RA2",
            "EOMES",
            "RELA",
            "MAP4K2",
            "NFKB1",
            "CTSS",
            "PSMB10",
            "MCL1",
            "TGFB1",
            "CXCL9",
            "ITLN1",
            "CCL24",
            "IL2",
            "SKI",
            "SMAD3",
            "SIGIRR",
            "IL1RL1",
            "PYCARD",
            "STAT2",
            "TNFRSF13C",
            "IFNAR2",
            "NFKBIA",
            "PSMB8",
            "PECAM1",
            "ETS1",
            "ZAP70",
            "TBX21",
            "C8G",
            "CAMP",
            "CCR7",
            "IKBKG",
            "TNFRSF4",
            "TLR7",
            "TRAF5",
            "STING1",
            "IL23A",
            "GPR183",
            "KLRF2"
        ],
        "Coefficient": [
            0.11708221359921142,
            -0.08570370112633462,
            0.08024944029342,
            0.07678957583143209,
            0.07598918264644587,
            -0.07477324612431993,
            0.0724695527756458,
            -0.07133907062085268,
            0.06979624175072274,
            0.06906233178998777,
            -0.06646137002148253,
            0.06628792612753166,
            -0.06446603199431399,
            -0.06407246255067015,
            0.06344718644769172,
            0.0633219481960405,
            0.06285677492339002,
            -0.06187810512969362,
            -0.05993910658234141,
            0.05849591460488159,
            0.05815576993869787,
            0.0577557090988577,
            0.056966498876262456,
            -0.056566311707829976,
            -0.05619339900606859,
            0.055912881285090865,
            -0.05558689861271072,
            0.05496577486790421,
            0.05496444651831604,
            -0.05405266450410948,
            -0.05375475646243815,
            -0.05340806647025915,
            0.05332831662062894,
            0.05308862170444972,
            -0.05241824708159165,
            -0.05200344395016282,
            -0.051759004808239494,
            0.0511134925513915,
            0.0509825993272042,
            0.050859150096074744,
            0.05084678624046866,
            0.0496100042718745,
            -0.049573683463807174,
            -0.049101845282057514,
            0.04883554214363663,
            0.048154946509466334,
            -0.04742043047779151,
            0.046551984624954884,
            0.0460145809492882,
            -0.04581322670384635,
            0.04579222257005142,
            -0.04560845456919992,
            -0.04548200143767825,
            0.04543025293612762,
            0.04479919394000932,
            -0.04478841832913828,
            0.04435746900212517,
            -0.043839056251117954,
            -0.043621639445966205,
            -0.043427245428280664,
            -0.043025296705217486,
            -0.04273672189975765,
            0.042463922843186,
            0.04233663177238682,
            0.042233120030360546,
            -0.0416808783425974,
            0.040691257668498355,
            -0.040073765855504456,
            0.039739295678185856,
            0.03920570022953006,
            0.0392006375601209,
            0.0388875544774631,
            0.03871214515971674,
            0.03842635595351921,
            -0.038329434505276594,
            0.038302906550848004,
            0.03823235069872003,
            0.03819779473080575,
            0.03793541392321599,
            -0.037853080345629536,
            -0.037779601619601644,
            0.03755033048859533,
            0.03749176494612644,
            0.03731307365220999,
            0.03724316322889111,
            -0.03714743624065196,
            -0.036996750893237895,
            0.03679895471340199,
            -0.03666227793856041,
            -0.03665459673732942,
            -0.03638936462646838,
            -0.036063752228162715,
            -0.03582580462130191,
            -0.035652733075953576,
            0.035364981486658974,
            0.03535359043561767,
            0.035209348591778336,
            -0.03519286114731639,
            0.03503678863871495,
            0.03475815948015347,
            0.034598842543224935,
            0.03407842064404595,
            -0.03363788951038387,
            -0.03354070647502043,
            -0.03335696620340385,
            0.0333010638121774,
            -0.03290540378677282,
            0.032880853378375485,
            -0.032818437840999866,
            0.032521691119617335,
            0.032477933703995175,
            -0.03228881880923677,
            -0.03226987497436374,
            -0.03215306561088425,
            -0.032021738772860395,
            -0.03173990745539729,
            -0.031643758820149914,
            0.03156317618189415,
            -0.031472670716137,
            0.03131893145192195,
            -0.030881037666330737,
            0.030862841914934214,
            0.030762563633155465,
            0.03056519483322153,
            0.030321253980850327,
            0.02949383776512462,
            0.02941110994192164,
            0.02932544435858117,
            0.02926357508109558,
            0.029171784020512778,
            0.029089100365534654,
            0.028952627819361934,
            -0.02885757200809125,
            -0.028599767176754422,
            -0.028588125708022546,
            -0.02846379208609071,
            0.028062198032318256,
            -0.02776430584840094,
            -0.027407660276908524,
            -0.02737790427468194,
            0.027128128301015977,
            -0.027109041176335537,
            -0.02708724881123443,
            -0.02703343825324926,
            0.02690023550896407,
            -0.026860310151860883,
            -0.026816053029208513,
            0.026810648803214206,
            0.026688358928337496,
            0.026669438524559913,
            -0.026485361554186432,
            -0.026472022447663852,
            0.026432113409329463,
            -0.02643175030667791,
            -0.026403984115509736,
            0.02619189820623591,
            -0.026149236718725075,
            -0.02593545109985829,
            -0.025927836182851056,
            -0.025905024157458812,
            -0.025867162759746723,
            -0.025861929326437123,
            0.025828765026975464,
            0.025730658881294326,
            0.025711589772859086,
            -0.025441020230865304,
            0.02539733502923795,
            0.025333793037782406,
            -0.025070866868032147,
            -0.025021762373010185,
            -0.025017480167247096,
            0.024977583421506327,
            -0.024845647046416952,
            -0.024795435392803947,
            0.024791081639118927,
            -0.024637361506773942,
            0.024607975796943078,
            -0.024605920050198092,
            -0.024467349516380108,
            -0.024451160767430487,
            0.024251949517291694,
            0.024210168989594855,
            -0.024205697671601894,
            0.024187825586595855,
            0.024123390872130408,
            0.023995976385007504,
            0.02395958652296493,
            -0.023896657484064686,
            0.023818557775448723,
            0.023593873365065715,
            -0.023453942589330912,
            0.023396428812530165,
            0.02334390713411031,
            -0.023295635614001227,
            0.023188518464082573,
            -0.023052518145690856,
            0.023001478691956883,
            -0.022996192848643474,
            0.022892589015891952,
            0.022821151668793522,
            0.02273465295077301,
            0.02258216122187458,
            -0.022569632880618848,
            -0.022515064709642943,
            -0.022490459467808255,
            -0.02238048061200436,
            -0.022167895106932164,
            0.022166739501727106,
            -0.02216328689228244,
            0.022112510173580773,
            -0.02203347751443783,
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            -0.021917869029953227,
            -0.021832408853394117,
            -0.021710776704396764,
            0.021587051205259892,
            -0.021481996352934782,
            -0.021458587353357074,
            -0.021449284675972145,
            0.021394366991682602,
            0.021355967029147726,
            0.021261768208467605,
            -0.021159860606147912,
            -0.020964312715051985,
            -0.02093296397881568,
            -0.020927826626411267,
            0.020787624063597073,
            0.020760594042174122,
            -0.020730569433604996,
            0.020564746052237487,
            -0.020509329478280512,
            -0.020444783112845193,
            0.020432203624553127,
            -0.02033856742381262,
            -0.020253863688608997,
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            -0.020167336850299766,
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            0.01975349103588879,
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            -0.01949944857974044,
            0.01935175193109915,
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            -0.019176818511809256,
            0.01901659861956945,
            0.018847152414418877,
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            -0.01878381198171928,
            -0.0187598340448203,
            -0.018746420068722795,
            -0.01874122531888983,
            -0.018593915410250912,
            -0.01859200397169908,
            0.01855079738387805,
            0.018365391744192404,
            0.01834541700955389,
            -0.018197720132103006,
            0.01811213230774472,
            0.018001558372015176,
            0.017960992329664183,
            -0.017794432113650338,
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