{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "B3GAT1",
            "C1R",
            "C4BPA",
            "BCAP31",
            "BTK",
            "C1QB",
            "CD40LG",
            "APP",
            "DEFB4A",
            "CCL8",
            "CXCR3",
            "IRAK2",
            "BCL2",
            "HLA-DQA1",
            "EBI3",
            "LILRB5",
            "MAPK14",
            "ADGRE2",
            "CCL15",
            "CD59",
            "TLR3",
            "C3",
            "TP53",
            "EGR2",
            "BATF",
            "FADD",
            "CD9",
            "IL1R1",
            "HRAS",
            "HFE",
            "CIITA",
            "LTB4R",
            "FKBP5",
            "CD86",
            "CXCR2",
            "DEFB103A",
            "CR2",
            "PTGS2",
            "BST2",
            "CD53",
            "CCL20",
            "CCL3",
            "FYN",
            "CARD9",
            "PSMB5",
            "CCND3",
            "PTAFR",
            "BCL3",
            "CTNNB1",
            "DEFB103B",
            "IL4R",
            "IL7",
            "SLC2A1",
            "NFATC2",
            "ATG16L1",
            "S1PR1",
            "FCAR",
            "IKZF1",
            "KLRC3",
            "CCL5",
            "CCR8",
            "CRADD",
            "POLR1G",
            "MBP",
            "IGF2R",
            "NT5E",
            "CD14",
            "CCL22",
            "MALT1",
            "IRGM",
            "MAPKAPK2",
            "IL6",
            "FN1",
            "FAS",
            "CFI",
            "IL17A",
            "IRF7",
            "ATG12",
            "TNFSF11",
            "CFH",
            "CD160",
            "LTB4R2",
            "CXCL11",
            "CD80",
            "CCRL2",
            "AIRE",
            "CD46",
            "ABL1",
            "FOXP3",
            "CCL13",
            "CD79B",
            "LCP2",
            "ACKR4",
            "CCL2",
            "ITGA5",
            "KLRA1P",
            "CD19",
            "NOTCH2",
            "RAG2",
            "FCER1A",
            "HLA-DRB3",
            "DEFB1",
            "SPP1",
            "IL22",
            "MUC1",
            "PSMC2",
            "CFD",
            "NOD2",
            "CD36",
            "FCGR2B",
            "ATG10",
            "CCL19",
            "LIF",
            "NLRP3",
            "SELPLG",
            "MAP4K4",
            "SELE",
            "IL13RA1",
            "PDCD1",
            "IL1RAP",
            "ZBTB16",
            "EGR1",
            "MX1",
            "ATG7",
            "GZMK",
            "IL10",
            "IL4",
            "EDNRB",
            "IL16",
            "IL32",
            "IL21R",
            "CFB",
            "IL1B",
            "CUL9",
            "BCL10",
            "BLNK",
            "BTLA",
            "CD1D",
            "IL21",
            "CD7",
            "TNFSF15",
            "STAT4",
            "CD4",
            "MSR1",
            "GP1BB",
            "POU2F2",
            "CSF2",
            "SLAMF6",
            "TLR4",
            "CD274",
            "IFI16",
            "AICDA",
            "ITLN2",
            "PDCD2",
            "IL1RN",
            "CLEC5A",
            "KCNJ2",
            "ITGA2B",
            "TIRAP",
            "IL26",
            "ITGB1",
            "TCF7",
            "BAX",
            "IL7R",
            "TNFSF8",
            "TOLLIP",
            "CD48",
            "TNFSF13B",
            "CD70",
            "CD1A",
            "IRF5",
            "CLEC6A",
            "IRF3",
            "TNFRSF17",
            "SLAMF1",
            "ITGA4",
            "KLRG1",
            "IL2RA",
            "CXCL8",
            "CCL16",
            "CCR6",
            "TGFBI",
            "CCR1",
            "PDCD1LG2",
            "RAG1",
            "IL3",
            "IFI35",
            "CX3CR1",
            "MAPK11",
            "CLU",
            "CCR2",
            "CTSC",
            "CCL4",
            "HLA-C",
            "MME",
            "CXCL1",
            "TAPBP",
            "IFNA2",
            "CASP8",
            "IRAK1",
            "TRAF1",
            "IRF4",
            "PRKCD",
            "PAX5",
            "HLA-DMB",
            "CD163",
            "UBE2L3",
            "LCK",
            "TLR1",
            "PTPN2",
            "IRAK4",
            "TNFRSF10C",
            "CCR10",
            "B2M",
            "MIF",
            "CCL26",
            "TAGAP",
            "IL12B",
            "HAVCR2",
            "CASP10",
            "C5",
            "CXCR6",
            "NCAM1",
            "IL6R",
            "CD8B",
            "CD58",
            "KLRG2",
            "MS4A1",
            "ENTPD1",
            "TCF4",
            "PSMB7",
            "ARHGDIB",
            "MYD88",
            "CD96",
            "CD164",
            "CDKN1A",
            "IL10RA",
            "IL15",
            "IFNL1",
            "CLEC4E",
            "ITGAL",
            "IKBKE",
            "ITGB2",
            "PLA2G2E",
            "TRAF4",
            "CCL23",
            "STAT1",
            "CD8A",
            "C1QA",
            "STAT3",
            "ICAM3",
            "BST1",
            "PML",
            "NFATC1",
            "TLR9",
            "ICAM1",
            "TLR2",
            "TNFSF12",
            "CEACAM6",
            "IL2RG",
            "CD99",
            "ADA",
            "IL27",
            "CXCL12",
            "CD28",
            "RELB",
            "HLA-DPA1",
            "CD276",
            "PLAU",
            "CSF1",
            "IFNAR1",
            "CSF2RB",
            "STAT5A",
            "IFIH1",
            "PDGFB",
            "PTGER4",
            "SMAD5",
            "SYK",
            "CXCL2",
            "MRC1",
            "IL6ST",
            "C6",
            "IFNB1",
            "TNFRSF9",
            "KLRB1",
            "TGFBR1",
            "XCL1",
            "ITGAM",
            "TLR5",
            "CD34",
            "CD74",
            "CD81",
            "PRDM1",
            "LILRB2",
            "CR1",
            "CCL11",
            "VCAM1",
            "NOTCH1",
            "C7",
            "IL2RB",
            "CD40",
            "IL17F",
            "CEBPB",
            "S100A8",
            "KIR3DL1",
            "KLRC1",
            "C1QBP",
            "NFKBIZ",
            "CD55",
            "IL20",
            "HAMP",
            "PSMD7",
            "IKBKB",
            "GATA3",
            "PLAUR",
            "FCGRT",
            "PDGFRB",
            "JAK3",
            "TLR8",
            "LAIR1",
            "LITAF",
            "CD2",
            "C1S",
            "CD3D",
            "HLA-A",
            "IL11RA",
            "TNFRSF1B",
            "FCGR2A",
            "THY1",
            "RTRAF",
            "IL5",
            "TRAF6",
            "IL1RL2",
            "XCR1",
            "ARG2",
            "CCL18",
            "IL18",
            "NCF4",
            "PRF1",
            "TNFRSF11A",
            "AHR",
            "IRAK3",
            "LAG3",
            "MR1",
            "CCR5",
            "CD83",
            "KIT",
            "SOCS3",
            "CX3CL1",
            "SERPING1",
            "BCL6",
            "LILRA6",
            "TBK1",
            "HLA-DPB1",
            "BID",
            "KLRF1",
            "GBP5",
            "LILRA1",
            "NFKB2",
            "GPI",
            "CD6",
            "TGFBR2",
            "LTA",
            "CASP2",
            "NOD1",
            "TNFSF4",
            "HLA-DOB",
            "ELP1",
            "TFRC",
            "GBP1",
            "IL23R",
            "ITGA6",
            "IFNL2",
            "ABCB1",
            "ARG1",
            "CCL7",
            "STAT6",
            "ICOS",
            "KIR3DL3",
            "C9",
            "TYK2",
            "CSF3R",
            "IFIT2",
            "CMKLR1",
            "IL12A",
            "MAF",
            "ITGAE",
            "LY96",
            "TNFRSF13B",
            "CYBB",
            "NOS2",
            "LILRB1",
            "LAMP3",
            "HLA-B",
            "IFNGR1",
            "CXCL13",
            "CEACAM8",
            "CLEC7A",
            "ICOSLG",
            "ICAM5",
            "SOCS1",
            "PSMB9",
            "TNFRSF8",
            "MAPK1",
            "CD244",
            "IKZF3",
            "CD247",
            "CD24",
            "IL9",
            "IKZF2",
            "IRF8",
            "ATM",
            "ILF3",
            "TAP2",
            "RUNX1",
            "PIGR",
            "TNF",
            "PTPN6",
            "CD5",
            "TIGIT",
            "MASP1",
            "PLAAT4",
            "LGALS3",
            "CD79A",
            "CD82",
            "HLA-DMA",
            "NCR1",
            "IRF1",
            "IL18RAP",
            "TNFRSF14",
            "CDH5",
            "IDO1",
            "HLA-DRB1",
            "CD27",
            "PTPN22",
            "CHUK",
            "CASP3",
            "DUSP4",
            "LILRA3",
            "CFP",
            "LTF",
            "LTBR",
            "RAF1",
            "IL13",
            "CD44",
            "GZMB",
            "HLA-DQB1",
            "PTK2",
            "MASP2",
            "RORC",
            "STAT5B",
            "LEF1",
            "PPARG",
            "XBP1",
            "TRAF3",
            "DPP4",
            "JAK1",
            "C2",
            "CSF1R",
            "SLAMF7",
            "ITGAX",
            "TNFSF10",
            "KLRC4",
            "IL18R1",
            "TRAF2",
            "LILRB3",
            "KLRC2",
            "HLA-DRA",
            "LILRA5",
            "CTSG",
            "GNLY",
            "IL19",
            "CLEC4A",
            "CISH",
            "ICAM4",
            "ICAM2",
            "NFATC3",
            "LILRA2",
            "CEACAM1",
            "ZEB1",
            "TICAM1",
            "CASP1",
            "MBL2",
            "TAL1",
            "TAP1",
            "IL1R2",
            "IL1A",
            "SH2D1A",
            "IFITM1",
            "VTN",
            "KIR3DL2",
            "IL12RB1",
            "GFI1",
            "CXCR4",
            "SRC",
            "KLRD1",
            "CXCL10",
            "LILRA4",
            "C8A",
            "IL17B",
            "GZMA",
            "NFIL3",
            "PPBP",
            "CTSS",
            "TNFAIP6",
            "LILRB4",
            "FCER1G",
            "IFNG",
            "CD22",
            "TNFAIP3",
            "CD3E",
            "JAK2",
            "ITLN1",
            "CD209",
            "CCL24",
            "S100A9",
            "CXCR1",
            "PLA2G2A",
            "RELA",
            "KLRK1",
            "MAP4K1",
            "MCL1",
            "SMAD3",
            "MARCO",
            "MAP4K2",
            "IL22RA2",
            "EOMES",
            "PSMB10",
            "SELL",
            "TGFB1",
            "STAT2",
            "IL2",
            "C8B",
            "CXCL9",
            "PSMB8",
            "IL1RL1",
            "NFKB1",
            "PECAM1",
            "NFKBIA",
            "SKI",
            "GPR183",
            "TRAF5",
            "SIGIRR",
            "CAMP",
            "TNFRSF13C",
            "IKBKG",
            "ZAP70",
            "IFNAR2",
            "CCR7",
            "ETS1",
            "TLR7",
            "TBX21",
            "TNFRSF4",
            "PYCARD",
            "IL23A",
            "C8G",
            "KLRF2",
            "STING1"
        ],
        "Coefficient": [
            0.11814366484330871,
            -0.0874907275774938,
            0.07959258570699687,
            0.07658645860582275,
            0.07588977312188608,
            -0.07404782350295391,
            0.07339169878400766,
            -0.07255196134685495,
            0.06958519346002524,
            0.06911731209794686,
            0.06749996481077085,
            -0.06558850479794408,
            -0.06526800473808252,
            0.0650040077683256,
            -0.06311675083502016,
            0.0628463022232802,
            0.06273612141689222,
            0.06219238634987284,
            -0.06038110592687226,
            -0.05949495526680278,
            -0.058612288696920214,
            0.057841091368728566,
            -0.057492727189899354,
            0.05661025666984566,
            0.05647023954190514,
            -0.05617469399821319,
            -0.05556455712059039,
            0.05536203580174397,
            -0.05534016304071442,
            -0.0547220178080524,
            0.05467189404180147,
            0.054184770909682836,
            -0.05369446961118687,
            0.05243766982506488,
            0.05217170581568306,
            -0.052005673206203126,
            -0.05152473232631186,
            0.051358367167133226,
            0.051211298240828866,
            0.050751621368122224,
            0.05013462682453027,
            0.0495604115996983,
            0.04934472313853114,
            -0.04864344270082043,
            -0.04735495264904836,
            0.04676580481347609,
            -0.04602891202077109,
            0.045881439643425406,
            0.04586415818790407,
            0.04581262551099294,
            -0.045626415475628665,
            -0.045286595110260244,
            0.04512101443163998,
            0.04436152954880078,
            -0.044319528114761385,
            0.04406431426597327,
            -0.043465949005853176,
            -0.04342146890350683,
            -0.04319783165152997,
            -0.04297259427345121,
            -0.042906681333581664,
            0.0426122017107907,
            0.04257208413487974,
            0.04207064546985966,
            -0.041995789650250144,
            0.0419905036167896,
            -0.04195717360319819,
            -0.03962958406255688,
            0.03898823993955751,
            0.03876408615762586,
            0.03841309613158595,
            -0.038382824221886463,
            0.038378804132062606,
            0.03834538304754598,
            0.03833642800725394,
            0.03831729504996955,
            0.03804135462642151,
            0.037489578008695915,
            -0.03748415883728428,
            0.03748369488224924,
            0.037369509747704484,
            -0.03721607330800481,
            0.037197544563317204,
            0.036869087508192455,
            0.03676965792368959,
            -0.036702936278758355,
            -0.03668600499820147,
            0.036440409042613926,
            -0.0363861635677794,
            -0.03631986042047284,
            -0.036197009733655874,
            -0.03617896755025741,
            -0.036108866117641,
            -0.035910676955997096,
            -0.03559220993000267,
            0.03537002857072656,
            0.03489433933012669,
            0.03460871033644361,
            0.0345565377418993,
            0.034539660858442865,
            0.034479633558878967,
            -0.033939089009460716,
            -0.0336128892053916,
            -0.033429717988733516,
            -0.03341665281153685,
            0.033238642861216805,
            0.033008352646660445,
            -0.032825775067615935,
            -0.03259712776619334,
            0.03258525975013264,
            -0.03206168586306051,
            -0.03197270559219446,
            -0.031720858226736634,
            0.03168260958330458,
            0.0316812001082199,
            0.03155100973217375,
            -0.031498639350540834,
            0.03147034290299964,
            0.03120725305125665,
            -0.03101094874765951,
            0.030923755128240714,
            0.03086932309871275,
            -0.030854164410069294,
            -0.03017873314426051,
            0.030169539464264424,
            0.029827866810844563,
            0.029601130685712747,
            -0.029511248121577526,
            -0.029056575159874,
            0.02894737392089333,
            0.028798342698922397,
            0.02874169212962192,
            0.028719876572245784,
            0.02835560912158019,
            -0.028326183076328636,
            -0.02820630090403311,
            0.0281161442347041,
            -0.02802703650203543,
            0.028014077564501434,
            -0.027777953090421165,
            0.027772256882641767,
            -0.027681574519033744,
            -0.027655416580103273,
            0.02713160894981482,
            -0.027079103183299782,
            -0.02703497305743107,
            -0.026851039798644907,
            -0.02684164933003578,
            -0.0268072985426379,
            0.026523626068552294,
            0.026468599312462763,
            -0.02642162705683922,
            -0.026364631419975665,
            0.026281245769714082,
            -0.026232673786186274,
            -0.026183306744440613,
            -0.025915508020673536,
            0.025797454001922127,
            -0.025782136989341873,
            -0.025775916260940616,
            0.025696082580100782,
            -0.025689497754115838,
            -0.02567821498626499,
            0.025661018766384443,
            0.025648938824253273,
            0.02562215391846946,
            -0.025616721002183075,
            0.02550038614052247,
            0.025496789970580396,
            -0.025481390218198587,
            -0.02490703096760549,
            0.024806044788477654,
            -0.024793089170432776,
            -0.024734922452901157,
            -0.02459457007179734,
            0.02456899610658869,
            0.024448461152555424,
            0.024435388787724294,
            -0.024289559801509687,
            -0.024193155667663398,
            -0.024123045128932683,
            0.024100767756639063,
            -0.02409613403808657,
            -0.024071607290507793,
            0.02396396469334972,
            0.023930037773387366,
            0.023815226937130722,
            0.023797183031251702,
            -0.023759946107367095,
            0.023523849451343077,
            -0.02336753886285933,
            0.023350556986479188,
            -0.023282204287239053,
            -0.02315273171096115,
            0.022864388474923385,
            -0.022830152897155197,
            -0.022784236926821144,
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            0.022707123704224792,
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            -0.0223131574990702,
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            -0.02224768414461192,
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            -0.022162132289638446,
            -0.022156949850091166,
            0.02199034725519382,
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            -0.021610203973101233,
            0.021588165986742767,
            -0.021464217433290682,
            -0.021445662865074773,
            -0.02138162110873534,
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            0.021240973811206543,
            0.021182229755006648,
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            -0.021064230879173564,
            -0.020916981513415072,
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            -0.020870992531976752,
            -0.020656336806281487,
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            0.018633014264598922,
            -0.01849666990919633,
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            -0.018392176570576294,
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            0.018370529604906045,
            0.01829020886742582,
            0.018212330471556737,
            0.01815469259494002,
            0.018074485516978305,
            0.017945463035696572,
            0.017866336114082473,
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