{
    "significant_genes": {
        "Variable": [
            "CDKN2B-AS1",
            "ABCC5",
            "AL590762",
            "AC007787",
            "ADAM12",
            "AK098263",
            "ATP8A2",
            "DDX11L2",
            "GEM",
            "CEACAM21",
            "CCDC138",
            "ADAMTS1",
            "AC104537",
            "CLIC5",
            "BSPRY",
            "AC002059",
            "ACO1",
            "CASC5",
            "AJ011981",
            "BTN3A2",
            "ASGR2",
            "CAND2",
            "GSDMB",
            "B3GNT9",
            "LILRA3",
            "C17orf99",
            "AC124997",
            "AC009237",
            "ALMS1P",
            "AC009133",
            "BMS1P6",
            "FAM24A",
            "ADRA2A",
            "CTD-2639E6",
            "ADORA2A",
            "AC005537",
            "RP11-1L12",
            "ACP5",
            "NEFL",
            "VSIG10",
            "AC092667",
            "APOPT1",
            "BC047644",
            "ATOH7",
            "BOLA3-AS1",
            "ACSBG2",
            "APELA",
            "TMEM45A",
            "FBLN5",
            "DIXDC1",
            "C1orf54",
            "ABCC9",
            "ATP7A",
            "CABP7",
            "C15orf48",
            "BOLA1",
            "C20orf85",
            "COG1",
            "ACTN3",
            "AX746830",
            "CNRIP1",
            "CNGA3",
            "ARHGAP39",
            "BRICD5",
            "CAB39L",
            "AK093362",
            "AC005498",
            "KCTD11",
            "CCRN4L",
            "SYCP2L",
            "ALDH7A1",
            "BC044614",
            "RP13-638C3",
            "ABCB9",
            "C1orf74",
            "ANKRD16",
            "PLD5",
            "AGAP11",
            "ARRDC1",
            "CLCN4",
            "AV4S1",
            "ARHGEF26",
            "CARS2",
            "ABCA2",
            "LGALS4",
            "AMFR",
            "ARRB1",
            "ACSF3",
            "HOXB8",
            "CCNT2-AS1",
            "C19orf33",
            "CCDC79",
            "BUB1B",
            "ASZ1",
            "CNNM4",
            "ALAS2",
            "CLEC3A",
            "ALG1",
            "ASPH",
            "RPH3A",
            "B3GAT1",
            "ANK2",
            "AK055967",
            "CKAP2",
            "COPG2",
            "CNPY1",
            "CAV2",
            "ACE2",
            "ANKRD36BP2",
            "CYP4Z2P",
            "CRCT1",
            "ACACA",
            "AKAP17A",
            "C1QTNF7",
            "ASAH2B",
            "ABCB6",
            "DEFA1",
            "CTD-3203P2",
            "DQ582785",
            "PEX6",
            "ABCC6",
            "ANKRD30BL",
            "FIBIN",
            "HIVEP3",
            "GPR1-AS",
            "APTR",
            "NGFRAP1",
            "ANKRD37",
            "AES",
            "KRT1",
            "AMIGO1",
            "RAPGEF4",
            "C3orf14",
            "ABHD6",
            "SPDYA",
            "MATN3",
            "ADCY10P1",
            "TRBV27",
            "AF198444",
            "AY927499",
            "FREM3",
            "ACOT12",
            "VNN1",
            "FLJ31356",
            "CST9L",
            "AX747639",
            "LRRC19",
            "ASTN1",
            "POLQ",
            "SYNM",
            "FCGR2B",
            "CLEC4F",
            "C10orf113",
            "AC092192",
            "IL12A",
            "CPVL",
            "ACTR3P2",
            "C14orf37",
            "CEACAM8",
            "DAP",
            "BOLL",
            "ASB16-AS1",
            "ERICH1",
            "NTPCR",
            "CEACAMP3",
            "AFAP1L2",
            "BC044765",
            "SPATS2L",
            "CLCN6",
            "KRTAP21-1",
            "RMDN3",
            "BTNL8",
            "ADH1A",
            "CXCL8",
            "C7orf71",
            "RGL1",
            "KRT23",
            "APOL1",
            "KRTAP3-3",
            "BTD",
            "AC004692",
            "RFPL3",
            "CKMT1A",
            "BHLHE40",
            "AREL1",
            "FUOM",
            "AK093205",
            "ANO3",
            "ECHDC3",
            "ZNF625",
            "ANKRD20A9P",
            "ACSL5",
            "ALMS1-IT1",
            "SLC22A16",
            "CLEC12B",
            "ABHD8",
            "CCL4",
            "AJAP1",
            "C17orf98",
            "AC005256",
            "DCUN1D2",
            "RP11-932O9",
            "ADRM1",
            "ABCB11",
            "DEFB1",
            "CD1B",
            "CFI",
            "SLC2A6",
            "EFNB2",
            "C12orf45",
            "PAQR6",
            "C7orf57",
            "ZNF607",
            "BC024169",
            "ARL16",
            "BC033323",
            "TUBBP5",
            "ATP1B4",
            "DEFB107A",
            "C5orf51",
            "CRIPAK",
            "ATP7B",
            "AP3S2",
            "GPR19",
            "MKRN3",
            "CASZ1",
            "C21orf119",
            "C17orf97",
            "CLEC4G",
            "MEOX1",
            "MGP",
            "CFD",
            "FAM118A",
            "BC039122",
            "ANXA10",
            "MRI1",
            "ITGA1",
            "DQ592442",
            "CHI3L1",
            "GYPB",
            "CDCP1",
            "FLJ31715",
            "ABCA11P",
            "ANKRD60",
            "AL109706",
            "HERC2P3",
            "HIST1H1C",
            "CPT1A",
            "PDE4D",
            "C8orf46",
            "ACIN1",
            "RAB38",
            "ACKR4",
            "COL18A1",
            "MTL5",
            "AF086126",
            "FAM19A2",
            "CCT6P1",
            "SLC38A11",
            "TIGD3",
            "CCL7",
            "CYB561",
            "ACPP",
            "C10orf12",
            "ACVR2B",
            "AK128734",
            "CTAG2",
            "LHX8",
            "CLEC16A",
            "CEBPA",
            "IL10",
            "ATP5B",
            "ANKRD20A1",
            "GPR111",
            "KLHL4",
            "C6orf10",
            "TADA2A",
            "MYL6B",
            "CES1",
            "GCM1",
            "IFRD2",
            "ACTR8",
            "TCEB1P3",
            "BC032026",
            "FLRT2",
            "ARHGAP44",
            "AURKA",
            "PSORS1C3",
            "POMK",
            "ABHD17A",
            "CAD",
            "C5orf47",
            "AOX1",
            "FGF19",
            "CRISPLD1",
            "FLNB",
            "COX6CP1",
            "RALY-AS1",
            "ZNF74",
            "MS4A12",
            "CYLC2",
            "BMP2",
            "ZSCAN1",
            "GTF2H2B",
            "C5orf66",
            "MMACHC",
            "ZNF251",
            "MGC4836",
            "CCDC83",
            "DYX1C1",
            "BC024027",
            "CTC-384G19",
            "C9orf69",
            "AL832615",
            "CHIAP2",
            "FCRL5",
            "DDIT4",
            "AC073321",
            "MMRN2",
            "TRPM4",
            "SIK1",
            "B3GALT4",
            "CLGN",
            "LECT2",
            "CCL3",
            "CALHM2",
            "ABCC13",
            "FNDC1",
            "AKR1A1",
            "ENTPD3",
            "HIATL2",
            "BEND3",
            "KLHL13",
            "RP11-305O6",
            "RP11-796E2",
            "CTA-390C10",
            "PRO2012",
            "DAB1",
            "VASH2",
            "PFKP",
            "MECP2",
            "EIF3CL",
            "LTF",
            "MX2",
            "OR5E1P",
            "RNASE3",
            "KAZN",
            "CRYBA1",
            "SLC22A1",
            "ARPC5L",
            "C12orf40",
            "MUS81",
            "PI15",
            "APOBEC3B",
            "BTRC",
            "IGHV7-81",
            "FAM132A",
            "RP13-30A9",
            "C6orf123",
            "ERGIC1",
            "PAF1",
            "DEFT1P",
            "ANKRD20A2",
            "CKMT1B",
            "ANKRD20A3",
            "ANKRD20A4",
            "CCL3L1",
            "CCL3L3"
        ],
        "Coefficient": [
            0.04459145196609936,
            0.04360277387867686,
            0.03954145829464958,
            0.0351468655614787,
            0.03485583553256466,
            0.034801332899423235,
            0.0338644991378192,
            -0.033362975480502675,
            -0.03101228382903046,
            0.030840742007219757,
            0.03049564931355523,
            -0.029641873602473154,
            0.029551973210016732,
            -0.029130334227125604,
            0.028151610189639898,
            -0.027971486634822292,
            0.027646662520919962,
            -0.026893690813909778,
            0.026730187080736975,
            0.026230111455039833,
            0.026037621694664264,
            -0.0257906740520985,
            -0.025679007028233766,
            -0.02532798561423328,
            -0.024446003854528484,
            0.024410357518890636,
            0.023898835823213026,
            0.023413331478787255,
            -0.023342564649582315,
            -0.0232965389218443,
            -0.0232603238055951,
            -0.02250189703951845,
            -0.021429859792271706,
            -0.020000667673751738,
            -0.019530975507098383,
            0.019494852880687988,
            0.019395538548591697,
            -0.0191381078423206,
            -0.018952445262226697,
            -0.01882644331661709,
            -0.01880267894784932,
            -0.018769538551234068,
            0.01866919657291294,
            0.018273003460136668,
            -0.01787130638156476,
            -0.017739044539806726,
            -0.017628101725062215,
            0.01754738178648996,
            -0.017268219041704825,
            0.016669700433890548,
            -0.016639369536151267,
            0.016531132948306326,
            0.016441375001432734,
            0.016241534798347494,
            0.01616985312426752,
            0.016047826952196014,
            -0.015913505757982074,
            0.015747349188894266,
            0.015567086554660207,
            -0.01554258399943203,
            -0.01515943979572602,
            -0.015115130076698709,
            -0.015081577686592084,
            -0.014906573061411833,
            0.01449791390011977,
            -0.014352008055978157,
            0.014140844090403237,
            -0.014001711232210088,
            -0.013993211486910429,
            -0.013720008559155878,
            0.01357453875532286,
            -0.013277964880391558,
            -0.012565858348122974,
            -0.012503135386546094,
            0.012343604717544468,
            0.012151863902666872,
            -0.012006886441085983,
            0.01197619493892043,
            -0.011947317294048314,
            -0.01190795632673758,
            0.011849793254253569,
            0.011755577346174138,
            -0.01174065628714842,
            -0.01148387270167155,
            0.011279600251374379,
            -0.011187913968199912,
            0.011116084461041313,
            -0.01102020541007429,
            0.011017986780237545,
            -0.01085134357686167,
            -0.010787225560423453,
            0.010610235695814185,
            0.010393597698437692,
            0.01038755283548574,
            -0.010253126348012311,
            -0.010228771225282028,
            0.010099208734434872,
            0.010014156549342065,
            0.009794005786409984,
            -0.009761968714928003,
            0.009681421130591285,
            -0.009573646382415311,
            0.009383440931996764,
            -0.009307920749800734,
            0.009222289652049012,
            0.00922227676309327,
            -0.009168273307090516,
            -0.009090715387910875,
            -0.009027977455925927,
            -0.008693643508011223,
            0.008607261380479092,
            0.008548702922972605,
            -0.008514953139036456,
            0.008494242577746293,
            0.00846273932509641,
            -0.008405682297314645,
            0.008197828202311522,
            0.008162322189592182,
            0.008158273920922377,
            -0.008008997976625895,
            -0.008005282847606127,
            0.007967177134319471,
            0.0079404465650129,
            0.007926113527876132,
            -0.007911727875719907,
            0.007873136392410501,
            -0.007826254851651553,
            -0.007796714868758774,
            -0.007579312106439156,
            -0.007502240847080544,
            0.0074335744679028155,
            0.007354861059453571,
            -0.0073480874029518695,
            -0.007312007435551499,
            0.007300951486120356,
            0.007261209871763298,
            0.007152337779359622,
            -0.006970402489426688,
            -0.0068695397858695596,
            0.006846711288532935,
            0.006598611410867722,
            0.006597250992150531,
            0.006587294226560611,
            0.006468223463126121,
            -0.0063846639387771685,
            -0.006232967086320645,
            0.006193109185561181,
            0.00616360095892795,
            -0.0058825196518612535,
            0.005863313270310864,
            0.005826463124165486,
            -0.005750521830187831,
            -0.005731897318342728,
            -0.005720026525279319,
            -0.00565466202580815,
            -0.005583196877690299,
            -0.005457272470355271,
            0.00529704299756433,
            0.005275216641780326,
            -0.005246164765321101,
            0.005147164837782648,
            -0.004973010656944014,
            -0.004827546058993461,
            0.004793146509255901,
            -0.004771414005945898,
            0.004696633383451503,
            -0.00468447629096902,
            0.004675704139402478,
            -0.004594565622787152,
            0.004481872046127123,
            -0.004308813718194793,
            0.004276213048144213,
            0.004233361827132738,
            0.0041914293718169834,
            -0.004158965778250188,
            0.004049398348586608,
            -0.004039315557720638,
            0.00403475239615112,
            0.0040058132831248434,
            -0.003972244135252998,
            -0.003922544815608379,
            -0.0038766777952157073,
            -0.0038603800106127403,
            0.0038241659325535297,
            0.003812129790328177,
            -0.003660848862401099,
            0.0036044489959835098,
            -0.003505508694651149,
            -0.00339107112592348,
            -0.0033513206131422398,
            -0.003348778688251845,
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            -0.003145848415275433,
            -0.003067701067709189,
            0.0030526559300927286,
            0.0030244090319666286,
            0.0029238831223556833,
            -0.002907672980096124,
            0.002836982419581737,
            -0.0027896334933837615,
            -0.002767595155207795,
            -0.0027083065056222122,
            0.0026846041051121258,
            0.002650648702698847,
            0.002551422725678519,
            -0.0025024631495527178,
            0.002458266458911878,
            0.00243626288729866,
            0.002355700806323148,
            -0.002348053999716935,
            -0.0023104727538492014,
            -0.002248021711672415,
            -0.002213201106327482,
            0.002168486457308089,
            0.0021419441227668316,
            0.0020567435520579052,
            0.002031323116983856,
            -0.002021781255079008,
            -0.0020205325503125757,
            0.0019806730128825367,
            0.0019312966900196646,
            -0.0019279697723642614,
            0.0018955644883644365,
            -0.001879946777077636,
            -0.0018741626034156735,
            0.0018536849535507566,
            -0.0018120511859546868,
            -0.0017684417471953288,
            0.001740788986257525,
            0.0017207229231426652,
            0.0017037767101744587,
            0.0016793985070891737,
            -0.0016747624610717446,
            -0.0016354844456330346,
            0.0016073379567293335,
            -0.001599015823361952,
            0.001490016725843291,
            -0.0014648742078744736,
            0.001407179658798274,
            0.0013621877586043796,
            0.0013087789652196028,
            0.00129085753955908,
            0.0012756386458836796,
            0.0011796956397407726,
            0.00115052049565121,
            -0.0011478517655947676,
            0.0011066020141666274,
            -0.0010702331470457292,
            -0.0010503936855646816,
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            0.0010060777213239378,
            0.0010018234844747856,
            -0.0009813873207856483,
            0.0009635446127319153,
            0.0009550664758804197,
            0.0009477710991753035,
            -0.0009408062165125764,
            0.0009362216210672532,
            0.0009045018692164383,
            -0.0008917128469722868,
            0.0008758012965982038,
            0.0008704574830759428,
            0.0008697734619847349,
            0.0008598266633243071,
            0.0008318023233628634,
            -0.0008075306793797885,
            0.0007783862608304661,
            -0.0007765540521972792,
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            -0.0007011110657132451,
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            0.0006686056243411444,
            0.0006253926742560428,
            -0.0006211130328331337,
            0.0006179401594738572,
            0.0006102959212758619,
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            0.0005551729204903823,
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            0.00048037186317122986,
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            0.0004262533340515748,
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            0.00033746532623548953,
            -0.0003273961229561928,
            -0.0002956493864895525,
            0.0002831155843601091,
            -0.0002782976363623272,
            -0.0002743367685340759,
            -0.0002637411243602057,
            0.0002555183177043971,
            0.00024719457112957804,
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            0.00016759496205593402,
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            0.00011827168053966911,
            -0.00011754875943284263,
            0.00010578947208233842,
            -0.00010332459584186836,
            -9.377219699187943e-05,
            7.742161964571458e-05,
            7.367181227719197e-05,
            -7.165937738707626e-05,
            -6.48635966090794e-05,
            6.118578934931113e-05,
            5.535187869603664e-05,
            5.2727559185344396e-05,
            5.2460471714544734e-05,
            3.245657959124141e-05,
            2.928061745252056e-05,
            -2.895519688684709e-05,
            2.0160559165159037e-05,
            1.419340415609953e-05,
            -1.3195081013183698e-05,
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