{
    "significant_genes": {
        "Variable": [
            "ULK4P2",
            "FAM83C",
            "GARIN5B",
            "TFAP2A",
            "NPPC",
            "TMPRSS11A",
            "SPDYE2",
            "GPCPD1",
            "PCDHGB2",
            "HORMAD1",
            "MINDY4",
            "OR10A3",
            "RGPD8",
            "PIGR",
            "FABP2",
            "LEP",
            "PLEKHG7",
            "C12orf54",
            "TBX20",
            "MGC15885",
            "RGS16",
            "OR11H12",
            "MYOC",
            "PNLIPRP1",
            "PDCL2",
            "H2AB1",
            "SLC36A2",
            "GAGE12J",
            "GPNMB",
            "FAM3B",
            "AS3MT",
            "S100G",
            "AMELX",
            "PRG1",
            "APOF",
            "FAM136BP",
            "PRM2",
            "FRMD1",
            "KRTAP10-4",
            "NEU2",
            "TAS2R1",
            "H2BC1",
            "NHERF4",
            "TEX38",
            "RSPO4",
            "MYO7B",
            "SLC36A3",
            "SLED1",
            "PRB4",
            "TRIM14",
            "LIPJ",
            "B3GNT9",
            "IGFL3",
            "SUN5",
            "CCDC198",
            "PCDHA8",
            "FREY1",
            "OR52M1",
            "S100A7",
            "C16orf90",
            "DIO3OS",
            "MIA2",
            "OR4S1",
            "DNAJC15",
            "TBC1D26",
            "MRAP",
            "CRYGB",
            "UGT1A7",
            "IDO1",
            "PRAME",
            "CXADRP3",
            "WT1",
            "ASPRV1",
            "SDHAP3",
            "CHODL-AS1",
            "LCE3A",
            "CPA6",
            "ADH1A",
            "NME6",
            "PCSK9",
            "BTLA",
            "AIRE",
            "PROX2",
            "KLC3",
            "STON1-GTF2A1L",
            "KRT3",
            "C10orf53",
            "LOC284009",
            "TNNI1",
            "PLGLA",
            "PCDHB2",
            "KLF14",
            "RHBG",
            "MYH8",
            "PRAMEF18",
            "OR52K2",
            "IQCF6",
            "TPRX1",
            "USP29",
            "UPK3BL1",
            "PRAMEF5",
            "ANGPTL3",
            "KRTAP9-2",
            "LRRC18",
            "PLA2G2C",
            "SNORD67",
            "CRYBB3",
            "ARGFX",
            "KASH5",
            "IFNA21",
            "RGPD5",
            "KCNH2",
            "AADACL4",
            "CFHR1",
            "H2BW2",
            "TMC3",
            "OR2T34",
            "F2",
            "SNORA3B",
            "DSCR9",
            "RHAG",
            "DDI1",
            "FABP12",
            "TBC1D3G",
            "SUPT20HL1",
            "LYPD4",
            "TBX10",
            "CCL1",
            "IL1B",
            "ZAN",
            "LRRC70",
            "ALDH1A1",
            "IFNA2",
            "DYNAP",
            "OR10Q1",
            "TRMT12",
            "AFM",
            "KRTAP9-9",
            "FAM138D",
            "RPA4",
            "SDR9C7",
            "KLK1",
            "CSPG4P2Y",
            "KRT12",
            "RNASE7",
            "PCDHB6",
            "TRIM10",
            "RBM48",
            "SPINK13",
            "OR56B1",
            "GOLGA8DP",
            "PCDHA9",
            "TBXT",
            "ZNF880",
            "ACE2",
            "FOXA3",
            "PXMP4",
            "LINC00589",
            "MS4A12",
            "PPIAL4A",
            "TMPRSS11BNL",
            "OR4C3",
            "SNX31",
            "MESD",
            "IGDCC4",
            "KCNK10",
            "CFHR4",
            "HNF1A",
            "CLP1",
            "FCRLA",
            "OR10H1",
            "RPS27",
            "NT5C1B",
            "OR56A4",
            "OR2AT4",
            "MOS",
            "XAGE3",
            "PXT1",
            "SMCO2",
            "TM6SF2",
            "GPR151",
            "LOC728024",
            "IHO1",
            "NDUFAF6",
            "TRIM60",
            "OR52I2",
            "FAM138B",
            "HTR2B",
            "CCDC196",
            "PCDHGB1",
            "VN1R4",
            "CATSPER4",
            "H4C6",
            "LY6S-AS1",
            "TTTY19",
            "KRTAP2-1",
            "LOC284788",
            "OR4C6",
            "ADGRF4",
            "CLDN25",
            "PCDHGA6",
            "OR1N2",
            "HCRTR1",
            "EGLN3",
            "OR5AN1",
            "OR6B3",
            "HNRNPCL1",
            "SLN",
            "CIB3",
            "STX19",
            "JAML",
            "HTR1A",
            "CPLX4",
            "OR8A1",
            "OR10S1",
            "TINAG",
            "MBD3L5",
            "SDHAF3",
            "GPR148",
            "FKSG29",
            "OR2M5",
            "MAGEC2",
            "RNASE11",
            "TAB3",
            "OR10G3",
            "RPL21P44",
            "EZR",
            "CEACAM7",
            "OR4K1",
            "LDLRAD1",
            "OR10X1",
            "SUSD1",
            "RGS13",
            "MUC21",
            "SNORA79",
            "ASZ1",
            "MIOX",
            "OR6T1",
            "OR6F1",
            "LINC02694",
            "ING1",
            "CPZ",
            "HLA-DQA2",
            "PAX4",
            "C16orf46",
            "KRTAP6-2",
            "LOC642929",
            "TDRD12",
            "USH1G",
            "A4GNT",
            "WDSUB1",
            "PPP1R14D",
            "SNORA5C",
            "ASCL3",
            "PCDHGA5",
            "OR2L1P",
            "CPS1",
            "CT47B1",
            "FAM47C",
            "ANKRD33",
            "OR2M1P",
            "NETO2",
            "FOXD4L5",
            "FAM99A",
            "RAG2",
            "KRT23",
            "LIN7A",
            "NAPSB",
            "ACTRT3",
            "TSBP1",
            "SOX3",
            "ANTXRL",
            "FSHR",
            "OR4M2",
            "POU1F1",
            "OR2T6",
            "APOBEC3A",
            "CD8A",
            "SEPTIN14",
            "PCDHB4",
            "ACTL10",
            "KRTAP4-7",
            "OR4X2",
            "HSF5",
            "ASIP",
            "CRISP3",
            "IFNK",
            "DPRX",
            "ARL14",
            "VWDE",
            "RNF186",
            "CLRN1-AS1",
            "WTIP",
            "RPL23AP7",
            "ESPNL",
            "PPAN-P2RY11",
            "MT4",
            "PAGE5",
            "CLCA3P",
            "TNK1",
            "MGAM",
            "SERPINF2",
            "ACTC1",
            "POLR2J2",
            "SSX8P",
            "HS3ST6",
            "SPMIP2",
            "OR11L1",
            "GUCY2GP",
            "HOXD8",
            "TMEM72",
            "WFDC10B",
            "PAGE1",
            "CYP4A22",
            "ERRFI1",
            "TAS2R3",
            "SPINK4",
            "SERPINB4",
            "ALDH7A1",
            "KLK15",
            "TTTY4C",
            "MGC27382",
            "FAM99B",
            "SLC15A1",
            "NANOS2",
            "DEFB129",
            "OR1F2P",
            "HELT",
            "POU4F3",
            "TCL1A",
            "UCP1",
            "OR5M3",
            "SNORA16B",
            "PCGEM1",
            "KLHL14",
            "NXPH2",
            "INHBA",
            "HCN4",
            "NCF1C",
            "RAET1G",
            "ZNF174",
            "PEDS1-UBE2V1",
            "MAGEB4",
            "CLEC12B",
            "PZP",
            "TNF",
            "IGFL2",
            "CD34",
            "OR51T1",
            "OR4C46",
            "OR1K1",
            "ADGRF1",
            "HAMP",
            "PSG5",
            "CLEC4GP1",
            "SMN2",
            "PSG3",
            "SCGB2B2",
            "SIGLEC6",
            "DMRTC1",
            "PACSIN3",
            "DPPA3",
            "MSGN1",
            "VPS72",
            "MUCL1",
            "TMEM179",
            "OR2B3",
            "OR51G2",
            "SNORA38B",
            "MLEC",
            "LOC730101",
            "NKAPP1",
            "DEFB115",
            "PABPC1P2",
            "NANOS1",
            "C1orf185",
            "PCDHGA8",
            "GNAT3",
            "GP2",
            "TRIM72",
            "EPS8L3",
            "OR1B1",
            "LGALS9B",
            "LRRC74A",
            "CERS3",
            "KRTAP19-6",
            "SLC12A1",
            "KRTAP20-4",
            "XCR1",
            "NEUROG2",
            "MAGEA5P",
            "MOGAT3",
            "EMC10",
            "FAM47A",
            "OR11H1",
            "LINC00200",
            "CST9",
            "FBXO6",
            "OR1S1",
            "PKD1L3",
            "LINC00479",
            "ITLN1",
            "FCRL3",
            "TUBAL3",
            "PPP1R2B",
            "ZNF594",
            "LCN1",
            "MSMB",
            "STRA8",
            "YIPF7",
            "ACSM6",
            "ANO2",
            "ARFGAP3",
            "CCDC38",
            "IL37",
            "TTC22",
            "OR5AP2",
            "RAD51AP2",
            "MRI1",
            "POLH",
            "CEACAM22P",
            "ESPNP",
            "HAO2",
            "LINC00588",
            "EDAR",
            "ZBED1",
            "HBG2",
            "FLACC1",
            "AVP",
            "FAM27E5",
            "SFTPA1",
            "RSPH6A",
            "TTTY22",
            "ALOX15",
            "AOX2P",
            "MID2",
            "SLFN14",
            "OR2M3",
            "PAX2",
            "HLA-DQA1",
            "COX6B2",
            "PRORSD1P",
            "TEX11",
            "SLC2A2",
            "CHST13",
            "HRNR",
            "DPPA2",
            "IL27",
            "CT45A1",
            "LINC00173",
            "RFPL3",
            "SELE",
            "SNORA36B",
            "SPANXN3",
            "SNORA69",
            "ZNG1A",
            "RBBP8NL",
            "ABCG5",
            "FLG2",
            "GLYCAM1",
            "ULK2",
            "LHFPL7",
            "TRIM77",
            "GPHA2",
            "H3-4",
            "ZNF334",
            "BTC",
            "LINGO3",
            "PCDHGB6",
            "ZNF311",
            "RAET1L",
            "GAGE12D",
            "CD300LD",
            "MAGEB18",
            "CFAP45",
            "SLC22A20P",
            "ESR1",
            "REC114",
            "HBG1",
            "CSTPP1",
            "LINC00469",
            "POLR2J3",
            "FGFBP1",
            "LCE3D",
            "ZNF625",
            "OR4D11",
            "CCL15",
            "SPATA18",
            "GUCY2F",
            "FBXL21P",
            "DHRS4-AS1",
            "FAAH2",
            "OR10AG1",
            "OR2T33",
            "MEOX1",
            "OIT3",
            "ADGRF3",
            "C22orf42",
            "PLSCR4",
            "HJV",
            "HULC",
            "GSTA5",
            "SAMD14",
            "SLC29A4",
            "SKINT1L",
            "PRR30",
            "FERD3L",
            "HBZ",
            "TG",
            "NDST4",
            "DEFB109A",
            "SLC10A2",
            "OR2T35",
            "L1TD1",
            "PAX8",
            "SLC26A5",
            "RUNX1-IT1",
            "CPXCR1",
            "NLRP9",
            "LOC284379",
            "SNAR-D",
            "PAGE3",
            "OR2T10",
            "LILRB5",
            "ALOX12",
            "FRG2",
            "LINC01565",
            "TFAP2D",
            "DPPA5",
            "OR10G2",
            "TBC1D29P",
            "SERPINB10",
            "SPINK6",
            "SYCP3",
            "SPACA3",
            "DEFB112",
            "MAT1A",
            "LCE2C",
            "GATA6",
            "CYP1A2",
            "NCR1",
            "HSFY1P1",
            "LAX1",
            "UBE2DNL",
            "ASB12",
            "MBL2",
            "ADGRF2P",
            "GARIN3",
            "SCARNA15",
            "ZP4",
            "OR2T12",
            "PRSS38",
            "LANCL3",
            "DEFA6",
            "INSL6",
            "MUC2",
            "OR4C13",
            "OR5P3",
            "OR10P1",
            "OR2A12",
            "KRT4",
            "PASD1",
            "CTH",
            "INTS4P2",
            "GP9",
            "PM20D1",
            "PDHA2",
            "TFDP1",
            "OR2G2",
            "SYNE4",
            "OR13C8",
            "ZSCAN5B",
            "GARIN6",
            "PRSS8",
            "GBP4",
            "PCDHGB3",
            "HSP90AB4P",
            "SLC22A16",
            "DAOA",
            "MBOAT4",
            "NPHP3-AS1",
            "MLPH",
            "PCDH10",
            "DELEC1",
            "SPINK5",
            "SULT1A1",
            "MAGEB2",
            "CCDC185",
            "OR6C76",
            "GDF7",
            "MT1B",
            "IL21"
        ],
        "Coefficient": [
            -0.8860844512386178,
            -0.7234859534786435,
            -0.6751313063090156,
            -0.6656168973998999,
            0.6260555221212132,
            0.607668432238348,
            0.593263583930703,
            -0.5908140411392979,
            -0.5649726463468983,
            0.5337053065571247,
            -0.4980715475655731,
            0.49731472621624767,
            -0.48197723380275076,
            -0.47840513281744096,
            0.4647741791202664,
            -0.44895992932711326,
            -0.44134916213295605,
            -0.4405140080146503,
            0.440367223478383,
            0.4329465926039769,
            -0.4324657458165468,
            0.4283240294212853,
            0.40271006573371576,
            -0.39588236020624035,
            0.39579158055357405,
            0.38923719614006286,
            0.38810186510256267,
            0.3755782137654766,
            0.37308455316023215,
            0.36855541656349355,
            0.3680671070235012,
            0.356820989301013,
            -0.35681185388454467,
            0.3526791448647834,
            -0.350583215699038,
            -0.3505153716447066,
            -0.34756673800951615,
            0.3393047844554681,
            -0.33741369488456374,
            0.33735476471824727,
            0.3371034033045072,
            0.3315554511432048,
            0.33024174055842076,
            -0.3285259987576052,
            0.32788631140489327,
            -0.3266042260900899,
            0.324691606844808,
            -0.3199862092988782,
            0.31983799454252626,
            0.31908000565981937,
            0.3182777355654579,
            -0.3168268064873609,
            -0.31671704650476035,
            0.31448963563793436,
            0.3120197452338439,
            0.3111409636316909,
            -0.3080872535388915,
            0.3066190887925536,
            0.30557706579882177,
            -0.30429251017672315,
            0.30418410465677115,
            0.3005885334905155,
            0.2944546160175495,
            0.2908258303049693,
            -0.2903495960693814,
            -0.2901058736883567,
            0.2861621462288905,
            -0.28613083440752485,
            -0.2848048715141645,
            -0.284022028329524,
            0.28133275671024477,
            -0.2803702322533943,
            0.28034667861628754,
            -0.2795345288070959,
            0.27851432667254455,
            -0.2785013752201649,
            0.27757062627822027,
            0.27642788689456815,
            0.27618175322419797,
            -0.2753643140834801,
            -0.27462513616611733,
            0.2745460648176994,
            0.2731796028606783,
            -0.2710188842518745,
            -0.2707858568283255,
            -0.2699600187584171,
            -0.268283833446063,
            0.2660817702023451,
            -0.2659531172625644,
            0.26445062934623587,
            0.26388600005847035,
            -0.26155230498632787,
            0.2597919433066727,
            0.25889858466142673,
            -0.2586745500468391,
            0.2585733538455059,
            -0.2578023978893274,
            -0.2560407780021299,
            -0.25541278902175973,
            -0.2552614355049913,
            -0.25458712231482006,
            0.25443945059258444,
            0.2539185702412895,
            0.25326422885266037,
            0.24753226353111815,
            -0.24689893308636773,
            -0.24533125694726704,
            0.2451749955756215,
            0.24309214889596334,
            -0.24129688639645824,
            0.2401935994375399,
            0.24010848818223393,
            -0.2395392315696848,
            -0.23663989202759705,
            0.23484223976167037,
            -0.2334286674064123,
            0.23312076573951215,
            -0.23309481328723042,
            -0.23198029745765492,
            -0.22948453186831094,
            -0.2285191323594286,
            0.2284422684099505,
            -0.22754652618613602,
            -0.2273959829302027,
            -0.22654652107984025,
            -0.2250249898613002,
            0.2248838644821901,
            -0.22468589387287227,
            0.22342155650286633,
            0.2209396589221407,
            0.2195994105944478,
            -0.2192464787935314,
            0.21913155468752699,
            0.21836070307882807,
            -0.2182314241781311,
            -0.21570677146936926,
            -0.21191520621426216,
            0.21039840715178984,
            -0.21009190878952147,
            -0.2100693481373022,
            -0.2098078520398038,
            -0.2093455296413812,
            0.20923066627295933,
            -0.20915656598374702,
            -0.20834093533044634,
            0.20725227772448074,
            -0.20409266942502316,
            -0.20345824985314928,
            -0.20075683702100908,
            0.19918559351266224,
            -0.19733102249067672,
            0.19648297715864077,
            -0.19541639580609016,
            0.19499610996608105,
            -0.1947772011511071,
            0.19361256030643204,
            -0.19288384835922304,
            0.19262188761903537,
            0.19256469477620924,
            -0.19232376841285628,
            0.1921075064054871,
            -0.1920981825221744,
            -0.1914003087230185,
            0.1880568570426241,
            0.18804406554376915,
            -0.18589536303721743,
            -0.1852819029737801,
            -0.184753804274056,
            0.18201127369127532,
            -0.18050101418470418,
            0.17959176888598,
            0.17862991895984884,
            -0.17836843410001005,
            -0.17812079426534683,
            -0.1780035213539611,
            0.17760600442308563,
            0.17664201138595914,
            -0.1764813127298746,
            0.1759338597868262,
            -0.17582996913655702,
            0.17481864815950748,
            0.17413450228716645,
            -0.17410645309278927,
            0.17322825912033965,
            -0.17269477486828785,
            0.17235761426875884,
            0.171789731450707,
            -0.17127861631732655,
            0.16955660001476294,
            -0.169479261143072,
            0.1676790821624321,
            -0.16763013512984398,
            0.16753705344340633,
            0.16726928251497905,
            0.1670016608823993,
            -0.16669502618293056,
            0.1663220062569576,
            0.1652655807571733,
            0.16501965446887487,
            0.16479879925463886,
            -0.1646608803315426,
            0.16336600504164375,
            -0.16306813818195462,
            0.16236953329097503,
            0.16231917525804865,
            -0.16226457327899932,
            0.1602681732716208,
            0.1601002758715974,
            -0.15883016168689343,
            -0.15781804991326714,
            0.1566782630279847,
            0.1559546977428036,
            -0.15580031162626123,
            -0.15529940115246743,
            0.15451192482493817,
            0.15439720279247185,
            0.1539182244929335,
            -0.15279925008815484,
            -0.15243987300669748,
            -0.15230634874272472,
            -0.15201179317855065,
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