{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "B3GAT1",
            "BCAP31",
            "C1R",
            "C4BPA",
            "BTK",
            "APP",
            "CD40LG",
            "C1QB",
            "CXCR3",
            "DEFB4A",
            "CCL8",
            "EBI3",
            "IRAK2",
            "HLA-DQA1",
            "CD59",
            "MAPK14",
            "LILRB5",
            "C3",
            "CCL15",
            "TLR3",
            "TP53",
            "BCL2",
            "EGR2",
            "FADD",
            "HFE",
            "IL1R1",
            "BATF",
            "HRAS",
            "LTB4R",
            "CD9",
            "ADGRE2",
            "DEFB103A",
            "FKBP5",
            "CR2",
            "CD53",
            "CXCR2",
            "CIITA",
            "FYN",
            "BST2",
            "CD86",
            "PTGS2",
            "CCL3",
            "DEFB103B",
            "PSMB5",
            "CCL20",
            "CTNNB1",
            "PTAFR",
            "ATG16L1",
            "FCAR",
            "CCND3",
            "IL4R",
            "CCL5",
            "SLC2A1",
            "S1PR1",
            "NFATC2",
            "KLRC3",
            "CARD9",
            "CCR8",
            "CRADD",
            "MBP",
            "IL7",
            "POLR1G",
            "IGF2R",
            "IKZF1",
            "NT5E",
            "IL6",
            "BCL3",
            "AIRE",
            "MAPKAPK2",
            "CD46",
            "ATG12",
            "CD14",
            "IRGM",
            "IRF7",
            "FN1",
            "ABL1",
            "ACKR4",
            "MALT1",
            "TNFSF11",
            "CCL13",
            "LTB4R2",
            "CXCL11",
            "IL17A",
            "CCL22",
            "CD80",
            "FAS",
            "CCRL2",
            "LCP2",
            "CD19",
            "ITGA5",
            "CFI",
            "CCL2",
            "FOXP3",
            "CD79B",
            "KLRA1P",
            "CFH",
            "FCER1A",
            "MUC1",
            "CD160",
            "NOTCH2",
            "HLA-DRB3",
            "DEFB1",
            "IL22",
            "RAG2",
            "CD36",
            "LIF",
            "SPP1",
            "SELPLG",
            "FCGR2B",
            "NLRP3",
            "CCL19",
            "NOD2",
            "PSMC2",
            "SELE",
            "MAP4K4",
            "IL1RAP",
            "PDCD1",
            "EGR1",
            "CFD",
            "IL13RA1",
            "IL10",
            "ATG7",
            "IL32",
            "CD7",
            "MX1",
            "GP1BB",
            "IL4",
            "CD274",
            "ZBTB16",
            "IL16",
            "CUL9",
            "TNFSF15",
            "CFB",
            "IL1B",
            "GZMK",
            "IL21",
            "IL21R",
            "CD1D",
            "POU2F2",
            "EDNRB",
            "STAT4",
            "SLAMF6",
            "CSF2",
            "BTLA",
            "IL7R",
            "CD48",
            "MSR1",
            "TLR4",
            "IFI16",
            "ITLN2",
            "TOLLIP",
            "PDCD2",
            "AICDA",
            "CD4",
            "IL1RN",
            "IL26",
            "ATG10",
            "KCNJ2",
            "SLAMF1",
            "KLRG1",
            "ITGA2B",
            "TNFSF8",
            "CXCL8",
            "CD70",
            "IRF5",
            "IRF3",
            "TNFSF13B",
            "CX3CR1",
            "IL3",
            "TIRAP",
            "ITGB1",
            "BCL10",
            "TCF7",
            "CLU",
            "TNFRSF17",
            "IFNA2",
            "CLEC5A",
            "IRAK4",
            "PDCD1LG2",
            "ITGA4",
            "BLNK",
            "CXCL1",
            "CASP8",
            "IRAK1",
            "CLEC6A",
            "PAX5",
            "IFI35",
            "RAG1",
            "CCL4",
            "MAPK11",
            "CCL16",
            "IL2RA",
            "TGFBI",
            "TNFRSF10C",
            "C5",
            "TAPBP",
            "HLA-DMB",
            "CD163",
            "TRAF1",
            "MME",
            "CD1A",
            "CCR10",
            "UBE2L3",
            "MIF",
            "IRF4",
            "HLA-C",
            "PRKCD",
            "CCR6",
            "B2M",
            "CTSC",
            "CCR2",
            "BAX",
            "LCK",
            "TLR1",
            "CD8B",
            "CD58",
            "PTPN2",
            "CD164",
            "CCR1",
            "IL12B",
            "TCF4",
            "CCL26",
            "TAGAP",
            "CD96",
            "HAVCR2",
            "IL6R",
            "PSMB7",
            "IFNL1",
            "CLEC4E",
            "NCAM1",
            "ITGAL",
            "MS4A1",
            "C1QA",
            "PLA2G2E",
            "TRAF4",
            "CCL23",
            "IL10RA",
            "CD99",
            "MYD88",
            "IKBKE",
            "IL15",
            "ITGB2",
            "CASP10",
            "NFATC1",
            "BST1",
            "CD28",
            "STAT1",
            "CXCR6",
            "KLRG2",
            "ADA",
            "CSF2RB",
            "ENTPD1",
            "ICAM3",
            "STAT3",
            "CDKN1A",
            "TLR9",
            "CSF1",
            "RELB",
            "ICAM1",
            "TNFSF12",
            "PLAU",
            "ARHGDIB",
            "CD8A",
            "STAT5A",
            "TLR2",
            "CEACAM6",
            "CXCL12",
            "CD74",
            "CXCL2",
            "PTGER4",
            "IL27",
            "SMAD5",
            "IL2RG",
            "IFNAR1",
            "PML",
            "HAMP",
            "CCL11",
            "PDGFB",
            "SYK",
            "KLRB1",
            "HLA-DPA1",
            "IFIH1",
            "PRDM1",
            "IFNB1",
            "MRC1",
            "ITGAM",
            "CD276",
            "TGFBR1",
            "LILRB2",
            "IL6ST",
            "TNFRSF9",
            "TLR5",
            "C6",
            "CD81",
            "CD40",
            "KLRC1",
            "CEBPB",
            "CD55",
            "PDGFRB",
            "XCL1",
            "VCAM1",
            "IKBKB",
            "TLR8",
            "IL17F",
            "S100A8",
            "IL5",
            "CD83",
            "NOTCH1",
            "CD34",
            "NFKBIZ",
            "IL2RB",
            "KIR3DL1",
            "IL20",
            "FCGRT",
            "PSMD7",
            "CX3CL1",
            "PLAUR",
            "ARG2",
            "LAIR1",
            "LAG3",
            "NCF4",
            "C1QBP",
            "C7",
            "MR1",
            "PRF1",
            "LITAF",
            "CCR5",
            "TRAF6",
            "HLA-A",
            "IL1RL2",
            "JAK3",
            "FCGR2A",
            "KIT",
            "KLRF1",
            "NFKB2",
            "RTRAF",
            "CD6",
            "LILRA6",
            "THY1",
            "IL11RA",
            "C1S",
            "GPI",
            "GATA3",
            "SERPING1",
            "ELP1",
            "CD3D",
            "LILRA1",
            "TNFRSF11A",
            "NOD1",
            "XCR1",
            "TNFRSF1B",
            "IL18",
            "CMKLR1",
            "HLA-DOB",
            "HLA-DPB1",
            "IRAK3",
            "CD2",
            "GBP5",
            "TBK1",
            "TGFBR2",
            "SOCS3",
            "GBP1",
            "BCL6",
            "IL23R",
            "CR1",
            "TNFSF4",
            "ARG1",
            "LTA",
            "TFRC",
            "CCL18",
            "CYBB",
            "CXCL13",
            "CCL7",
            "CSF3R",
            "AHR",
            "ICOS",
            "ITGA6",
            "CASP2",
            "LY96",
            "C9",
            "TYK2",
            "KIR3DL3",
            "IFNL2",
            "STAT6",
            "LAMP3",
            "BID",
            "TNF",
            "TNFRSF8",
            "LILRB1",
            "IL12A",
            "ITGAE",
            "PSMB9",
            "TNFRSF13B",
            "IRF8",
            "NOS2",
            "CD247",
            "CDH5",
            "IFNGR1",
            "CD244",
            "HLA-B",
            "CHUK",
            "ILF3",
            "IFIT2",
            "ICAM5",
            "SOCS1",
            "MAPK1",
            "TNFRSF14",
            "IL18RAP",
            "DUSP4",
            "CEACAM8",
            "CASP3",
            "IL9",
            "IKZF2",
            "TAP2",
            "LILRA3",
            "MAF",
            "ICOSLG",
            "PLAAT4",
            "HLA-DRB1",
            "TIGIT",
            "RUNX1",
            "PIGR",
            "IKZF3",
            "ATM",
            "CD79A",
            "LGALS3",
            "CLEC7A",
            "PTPN6",
            "CD27",
            "CD5",
            "MASP1",
            "HLA-DMA",
            "CD24",
            "IRF1",
            "IDO1",
            "NCR1",
            "CSF1R",
            "TRAF3",
            "PPARG",
            "IL13",
            "LTF",
            "TNFSF10",
            "XBP1",
            "JAK1",
            "STAT5B",
            "LTBR",
            "CD44",
            "CASP1",
            "PTPN22",
            "LEF1",
            "CFP",
            "RORC",
            "HLA-DQB1",
            "ITGAX",
            "RAF1",
            "GZMB",
            "KLRC4",
            "LILRB3",
            "TRAF2",
            "PTK2",
            "MASP2",
            "KLRC2",
            "SLAMF7",
            "CTSG",
            "GFI1",
            "CD82",
            "IL1R2",
            "CXCL10",
            "DPP4",
            "TAL1",
            "ZEB1",
            "IL18R1",
            "MBL2",
            "VTN",
            "TICAM1",
            "LILRA2",
            "NFATC3",
            "HLA-DRA",
            "IL19",
            "ICAM4",
            "IFNG",
            "LILRA5",
            "CISH",
            "CXCR4",
            "KLRD1",
            "CTSS",
            "IL1A",
            "TAP1",
            "LILRA4",
            "SH2D1A",
            "PPBP",
            "GNLY",
            "CLEC4A",
            "ABCB1",
            "GZMA",
            "CEACAM1",
            "CXCL9",
            "KIR3DL2",
            "IL17B",
            "CD209",
            "RELA",
            "C8A",
            "EOMES",
            "LILRB4",
            "CD3E",
            "IL12RB1",
            "ICAM2",
            "SRC",
            "C2",
            "CCL24",
            "IL1RL1",
            "CD22",
            "PSMB10",
            "SMAD3",
            "ITLN1",
            "IL22RA2",
            "IFITM1",
            "STAT2",
            "MAP4K2",
            "CXCR1",
            "MAP4K1",
            "TLR7",
            "GPR183",
            "S100A9",
            "JAK2",
            "KLRK1",
            "SELL",
            "ZAP70",
            "NFKBIA",
            "PLA2G2A",
            "NFIL3",
            "PSMB8",
            "FCER1G",
            "IL23A",
            "PECAM1",
            "TNFAIP3",
            "C8B",
            "IKBKG",
            "IL2",
            "CCR7",
            "TNFAIP6",
            "SKI",
            "TNFRSF13C",
            "MARCO",
            "TGFB1",
            "MCL1",
            "ETS1",
            "SIGIRR",
            "IFNAR2",
            "KLRF2",
            "TNFRSF4",
            "PYCARD",
            "NFKB1",
            "C8G",
            "CAMP",
            "STING1",
            "TRAF5",
            "TBX21"
        ],
        "Coefficient": [
            0.11545340883266886,
            -0.086759966669568,
            0.08340420888060858,
            0.07715063935946884,
            0.0765634352931088,
            0.07561465344249187,
            -0.07426181242283093,
            -0.07285148120062092,
            0.07021828247335637,
            0.06960736485668415,
            0.06957025569822184,
            0.06656473420195676,
            -0.06567668225171501,
            -0.06461722937021885,
            0.06450444485646409,
            -0.0628665437581968,
            0.06270403606988201,
            -0.061786109416074014,
            -0.059778670390642115,
            -0.05932081086534243,
            0.05894700095255609,
            0.057729010785393435,
            0.05759552208669627,
            -0.05639255837765731,
            0.056382977545182913,
            -0.05621640388505176,
            -0.05537147812451394,
            -0.05466230189490238,
            0.05344336108063797,
            0.0533994318205374,
            0.053372481254930354,
            0.05286255056747683,
            -0.052547283974159434,
            -0.05251447738840465,
            0.052163567239562975,
            -0.05181045331481278,
            0.05180598425958666,
            0.05114770625215525,
            0.05099344712049278,
            0.05089839152667461,
            0.05015538806207789,
            0.04972867117842216,
            -0.049562729345950726,
            0.049372523024491674,
            -0.047163369399194105,
            0.047068275121433426,
            0.04646986261978511,
            -0.04618816471347503,
            -0.04602732231031706,
            0.045001628899819145,
            -0.04448207292127041,
            -0.0444715628948276,
            0.04446976530752887,
            0.0444034921031834,
            0.04419461601184578,
            0.044179779819608495,
            -0.04412422530573074,
            -0.04344765220141993,
            0.04318000611962582,
            -0.042813005858479074,
            0.04224413936367063,
            -0.04214008063088229,
            -0.04191156995370039,
            -0.041895003848939814,
            0.04176929151002131,
            -0.04120189559422319,
            -0.0410318162558579,
            0.040065703274787035,
            0.0398148893350904,
            -0.03977221350800035,
            -0.03958410282680791,
            0.03910020489777414,
            -0.0390878442901982,
            0.03897099138338496,
            0.038955427136146435,
            0.03892231043983046,
            0.03801646582464358,
            0.03780579039132278,
            -0.037784657913212366,
            0.037699931911622415,
            -0.03769663592347973,
            -0.037486833461389535,
            -0.03747787856170612,
            0.03731536265467772,
            -0.03711763825436172,
            -0.036960317551165384,
            0.03682674556911436,
            -0.036483010385031905,
            0.036410858367162305,
            0.03638131391329091,
            -0.03633837044432888,
            0.03613231672163743,
            0.03611100704712703,
            0.0359672862053622,
            0.0356908987347372,
            -0.03521783732977634,
            -0.03501180307250681,
            0.03488948035851056,
            0.03463898107998772,
            -0.03438248778725731,
            -0.03419202613785016,
            0.03394603925489537,
            0.03379927053147696,
            -0.03363122604223661,
            -0.033527625915192635,
            0.03318184749420439,
            -0.03295310947254472,
            -0.03268257195429434,
            0.032560680134943364,
            0.0325193647875964,
            0.032326233504143716,
            -0.03229546738558885,
            -0.032276438933055575,
            0.03226562002288423,
            -0.032190649057230104,
            -0.032088032288935864,
            -0.031988298525106436,
            0.03155215792378619,
            -0.03151678588027256,
            0.03095182890377953,
            0.030116798925074625,
            0.030105712925080866,
            0.03002786163263579,
            -0.02993950320482163,
            0.02965246307485905,
            0.029311343474810382,
            -0.02928078918562208,
            0.029208029484516052,
            -0.028857969973493134,
            0.02882389473874926,
            -0.0288046921471616,
            -0.02879498068082626,
            0.028748294480286953,
            0.02865049705475178,
            0.02852890194402672,
            -0.028435811993825454,
            -0.028367942863408005,
            -0.02808034640026065,
            -0.02806024507327019,
            0.028055665826727444,
            0.027936977360251393,
            -0.02791615293351699,
            0.027766563228033714,
            -0.027264037168872914,
            0.027158659706836345,
            0.027017645592848683,
            -0.02671985221199339,
            -0.026707440979772446,
            -0.02666240300711862,
            -0.026642657746852653,
            -0.026418689956603503,
            0.026395018949221985,
            -0.026391382490103883,
            0.026088622030521855,
            -0.026053774891108272,
            -0.02603640870503908,
            -0.026033424377174152,
            0.02582497313659735,
            -0.025725514577745603,
            0.025709057957514676,
            -0.0256451001878846,
            0.025524157049293845,
            -0.025481036749032467,
            0.02538065990205169,
            0.025335311635835384,
            0.025318925198295563,
            0.025213631671813518,
            -0.02517863305704097,
            0.025109709638292496,
            -0.025047245249791055,
            -0.024945931381942014,
            -0.024918605408372162,
            -0.0249147059051643,
            0.024786335694712024,
            -0.02475433936272572,
            0.02470699969134297,
            -0.024662205505444474,
            0.024598876957144234,
            -0.02448217314408704,
            -0.02428022981041608,
            -0.024265910593456837,
            0.02420573973773711,
            -0.02408312111102143,
            0.024058476971092486,
            0.024000021823449926,
            0.02398111643304674,
            0.02391520895302275,
            -0.023790001860850347,
            -0.023529264545776783,
            0.023521052020746516,
            0.023492555053136716,
            -0.02346349899917519,
            0.023358463352876606,
            -0.02334405192984521,
            -0.02306067257909197,
            0.022984538851376825,
            -0.02279580033615709,
            -0.022759504369588724,
            0.022742503545380238,
            0.022677264483079846,
            0.022599728393467224,
            -0.02230054192325811,
            -0.022233639296078165,
            -0.022168020289761368,
            -0.021975474856772356,
            -0.02194014463705556,
            0.021877605646618736,
            0.02179737077910513,
            -0.02174407586828086,
            -0.02173505570506812,
            -0.021695758435058315,
            -0.021665996866186647,
            0.021653106153162443,
            -0.021636005336377943,
            0.021570688299905445,
            0.021513149846115333,
            -0.02131297191934658,
            0.02129905845743387,
            -0.021221250531751806,
            0.021033639703281537,
            -0.021027383829551435,
            0.02100876751881344,
            0.020718805573645447,
            -0.0206920455213332,
            0.020622359298152343,
            -0.020561042612259394,
            -0.020523287938625994,
            -0.020495310658618537,
            0.02027369257080067,
            0.02023152381289743,
            0.020189051274008364,
            0.020150904718164185,
            -0.020126250256851958,
            0.019841242664988008,
            -0.019731645302508226,
            -0.01969368987414908,
            0.01963947209778615,
            -0.019619755933302268,
            -0.01955757456916808,
            0.01952391207250088,
            0.019516436641042363,
            0.01950529711836973,
            -0.01943897446218644,
            -0.019284630690977855,
            0.01917491736162543,
            -0.019137656096821044,
            0.019016596320250833,
            0.019003366616117946,
            -0.01893099965435583,
            0.018849914555987366,
            -0.01877939627056506,
            0.0187587688706762,
            0.018713108503942984,
            0.018702251794513198,
            -0.018672717872276794,
            -0.01844652321943797,
            -0.01841190456838386,
            -0.018333408108291028,
            0.01832564205668529,
            -0.018302354399108812,
            0.018265084437123148,
            0.01821902839858488,
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