{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "C1R",
            "BTK",
            "BCAP31",
            "C4BPA",
            "B3GAT1",
            "APP",
            "C1QB",
            "DEFB4A",
            "CD40LG",
            "CCL8",
            "IRAK2",
            "CXCR3",
            "HLA-DQA1",
            "BCL2",
            "ADGRE2",
            "LILRB5",
            "MAPK14",
            "CCL15",
            "EBI3",
            "CD59",
            "TLR3",
            "TP53",
            "C3",
            "FADD",
            "EGR2",
            "HRAS",
            "IL1R1",
            "FKBP5",
            "CD9",
            "HFE",
            "CR2",
            "CD86",
            "CXCR2",
            "LTB4R",
            "CIITA",
            "BATF",
            "BST2",
            "PTGS2",
            "DEFB103A",
            "CD53",
            "DEFB103B",
            "CCND3",
            "FYN",
            "PTAFR",
            "CTNNB1",
            "PSMB5",
            "BCL3",
            "CCL20",
            "CCL3",
            "CCL5",
            "IL4R",
            "KLRC3",
            "IL7",
            "CRADD",
            "S1PR1",
            "POLR1G",
            "NFATC2",
            "SLC2A1",
            "CARD9",
            "IKZF1",
            "MBP",
            "ATG16L1",
            "CD160",
            "FCAR",
            "CCR8",
            "NT5E",
            "CCL22",
            "CD14",
            "MALT1",
            "IGF2R",
            "CFI",
            "MAPKAPK2",
            "ACKR4",
            "CCL13",
            "FOXP3",
            "IRGM",
            "FAS",
            "IL6",
            "IRF7",
            "FN1",
            "LTB4R2",
            "IL17A",
            "CD46",
            "CCL2",
            "TNFSF11",
            "CCRL2",
            "CD19",
            "ATG10",
            "CXCL11",
            "CD79B",
            "NOTCH2",
            "LCP2",
            "CFH",
            "CFD",
            "AIRE",
            "KLRA1P",
            "FCGR2B",
            "MUC1",
            "ATG12",
            "RAG2",
            "ITGA5",
            "IL22",
            "EGR1",
            "MAP4K4",
            "FCER1A",
            "CD80",
            "NOD2",
            "CD36",
            "NLRP3",
            "HLA-DRB3",
            "LIF",
            "PSMC2",
            "SELPLG",
            "CCL19",
            "SPP1",
            "DEFB1",
            "BLNK",
            "ABL1",
            "PDCD1",
            "GZMK",
            "MX1",
            "IL4",
            "SELE",
            "ZBTB16",
            "IL21",
            "IL1RAP",
            "CUL9",
            "IL13RA1",
            "IL1B",
            "IL16",
            "IL21R",
            "ATG7",
            "KCNJ2",
            "IL10",
            "AICDA",
            "EDNRB",
            "CD4",
            "IL32",
            "TNFSF15",
            "CD1D",
            "ITLN2",
            "CCR6",
            "IL2RA",
            "CSF2",
            "CFB",
            "TLR4",
            "STAT4",
            "ITGB1",
            "HLA-C",
            "CD1A",
            "TNFSF8",
            "PDCD2",
            "POU2F2",
            "CD7",
            "BAX",
            "MSR1",
            "CD274",
            "CLEC6A",
            "IL26",
            "CD8B",
            "SLAMF6",
            "BCL10",
            "TIRAP",
            "IFI16",
            "BTLA",
            "CD96",
            "GP1BB",
            "TCF7",
            "ITGA4",
            "CD70",
            "ITGA2B",
            "TNFRSF17",
            "IL3",
            "TNFSF13B",
            "IRF5",
            "CCL16",
            "IFI35",
            "CLU",
            "IL7R",
            "CCR2",
            "IL1RN",
            "IRF3",
            "PDCD1LG2",
            "CCR1",
            "TGFBI",
            "TOLLIP",
            "RAG1",
            "SLAMF1",
            "TAPBP",
            "CCL4",
            "CXCL1",
            "IL6R",
            "CLEC5A",
            "IRAK1",
            "CXCL8",
            "TRAF1",
            "CTSC",
            "IFNA2",
            "KLRG1",
            "MAPK11",
            "MME",
            "KLRG2",
            "PAX5",
            "TNFRSF10C",
            "ARHGDIB",
            "PRKCD",
            "ENTPD1",
            "UBE2L3",
            "PTPN2",
            "TLR1",
            "IRAK4",
            "TAGAP",
            "IRF4",
            "MS4A1",
            "CDKN1A",
            "CCR10",
            "CD48",
            "MYD88",
            "IL12B",
            "C5",
            "NCAM1",
            "PSMB7",
            "LCK",
            "B2M",
            "CX3CR1",
            "CD163",
            "HLA-DMB",
            "TCF4",
            "CASP8",
            "ICAM3",
            "ADA",
            "BST1",
            "MIF",
            "IL15",
            "IKBKE",
            "PML",
            "C1QA",
            "CXCR6",
            "CASP10",
            "TLR9",
            "PLA2G2E",
            "CCL26",
            "HAVCR2",
            "CD58",
            "ITGAL",
            "IFNL1",
            "IL2RG",
            "ICAM1",
            "TLR2",
            "RELB",
            "TRAF4",
            "TNFSF12",
            "NFATC1",
            "CD276",
            "PLAU",
            "CSF1",
            "CEACAM6",
            "STAT1",
            "ITGB2",
            "CD164",
            "CXCL2",
            "CD99",
            "STAT3",
            "CXCL12",
            "MRC1",
            "CCL18",
            "CCL23",
            "CLEC4E",
            "NOTCH1",
            "HLA-DPA1",
            "CD81",
            "CD40",
            "IL10RA",
            "XCL1",
            "C1QBP",
            "KLRB1",
            "C6",
            "TGFBR1",
            "STAT5A",
            "IL27",
            "CSF2RB",
            "CR1",
            "SMAD5",
            "SYK",
            "ITGAM",
            "CD28",
            "CD8A",
            "KIR3DL1",
            "CD34",
            "VCAM1",
            "IFNAR1",
            "GATA3",
            "PTGER4",
            "CEBPB",
            "TNFRSF9",
            "IFNB1",
            "TLR5",
            "IL6ST",
            "CD2",
            "PRDM1",
            "LILRB2",
            "C7",
            "PDGFB",
            "NFKBIZ",
            "LAIR1",
            "IL17F",
            "LITAF",
            "C1S",
            "TNFRSF1B",
            "CD55",
            "S100A8",
            "IL2RB",
            "FCGRT",
            "IFIH1",
            "TRAF6",
            "IL20",
            "IL18",
            "PSMD7",
            "KLRC1",
            "ARG1",
            "GBP5",
            "CD74",
            "HLA-A",
            "PLAUR",
            "XCR1",
            "LAG3",
            "CCL11",
            "HAMP",
            "TNFRSF11A",
            "TLR8",
            "PDGFRB",
            "ARG2",
            "IRAK3",
            "GPI",
            "THY1",
            "NCF4",
            "JAK3",
            "RTRAF",
            "SOCS3",
            "IFNL2",
            "FCGR2A",
            "LILRA1",
            "CASP2",
            "CD83",
            "HLA-B",
            "IL11RA",
            "IKBKB",
            "HLA-DPB1",
            "BCL6",
            "TFRC",
            "TGFBR2",
            "MR1",
            "ITGA6",
            "KIT",
            "SERPING1",
            "KIR3DL3",
            "NFKB2",
            "PRF1",
            "STAT6",
            "IL5",
            "TNFSF4",
            "CD6",
            "TNFRSF13B",
            "IFNGR1",
            "CLEC7A",
            "LILRA6",
            "LTA",
            "IL1RL2",
            "MAF",
            "IL23R",
            "NOD1",
            "TBK1",
            "IL12A",
            "CSF3R",
            "NOS2",
            "CD3D",
            "ELP1",
            "HLA-DOB",
            "IFIT2",
            "TYK2",
            "ITGAE",
            "CYBB",
            "LILRB1",
            "CCR5",
            "GBP1",
            "AHR",
            "CMKLR1",
            "C9",
            "ICOSLG",
            "SOCS1",
            "CX3CL1",
            "PIGR",
            "KLRF1",
            "HLA-DMA",
            "ICOS",
            "LY96",
            "PSMB9",
            "LAMP3",
            "CEACAM8",
            "ILF3",
            "CD244",
            "TNF",
            "PTPN6",
            "IRF8",
            "IRF1",
            "CEACAM1",
            "CD82",
            "CD5",
            "BID",
            "CDH5",
            "MAPK1",
            "CCL7",
            "PLAAT4",
            "ICAM5",
            "TNFRSF8",
            "IKZF3",
            "CFP",
            "MASP1",
            "TIGIT",
            "RUNX1",
            "ICAM2",
            "LILRA3",
            "CD79A",
            "NCR1",
            "TNFRSF14",
            "TAP2",
            "IDO1",
            "CASP3",
            "CD44",
            "PTPN22",
            "CHUK",
            "IKZF2",
            "RORC",
            "PTK2",
            "CD27",
            "LTBR",
            "CXCL13",
            "GFI1",
            "IL18RAP",
            "DUSP4",
            "GZMB",
            "IL9",
            "HLA-DQB1",
            "IL13",
            "STAT5B",
            "C2",
            "LGALS3",
            "RAF1",
            "MASP2",
            "CD247",
            "CD24",
            "SLAMF7",
            "ABCB1",
            "TRAF2",
            "PPARG",
            "TNFSF10",
            "IL1R2",
            "LTF",
            "CISH",
            "XBP1",
            "HLA-DRB1",
            "TICAM1",
            "LEF1",
            "DPP4",
            "IL19",
            "CSF1R",
            "KLRC2",
            "CTSG",
            "LILRA5",
            "TRAF3",
            "IL18R1",
            "FCER1G",
            "ICAM4",
            "HLA-DRA",
            "ATM",
            "IL1A",
            "ITGAX",
            "KLRC4",
            "TAP1",
            "CLEC4A",
            "JAK1",
            "GNLY",
            "MBL2",
            "LILRB3",
            "CASP1",
            "LILRA2",
            "CXCL10",
            "IL12RB1",
            "ITLN1",
            "CXCR4",
            "CD22",
            "ZEB1",
            "NFATC3",
            "KLRD1",
            "SH2D1A",
            "C8A",
            "CD3E",
            "MARCO",
            "LILRA4",
            "KIR3DL2",
            "MAP4K2",
            "GZMA",
            "TNFAIP6",
            "CXCR1",
            "VTN",
            "TAL1",
            "SRC",
            "IKBKG",
            "GPR183",
            "RELA",
            "MCL1",
            "NFIL3",
            "SELL",
            "LILRB4",
            "CTSS",
            "S100A9",
            "TGFB1",
            "CD209",
            "IFNAR2",
            "CCR7",
            "EOMES",
            "SMAD3",
            "IFITM1",
            "KLRK1",
            "IL17B",
            "TBX21",
            "IL2",
            "JAK2",
            "PSMB10",
            "TNFRSF13C",
            "C8B",
            "PLA2G2A",
            "NFKB1",
            "PSMB8",
            "C8G",
            "STAT2",
            "MAP4K1",
            "IL22RA2",
            "PPBP",
            "CXCL9",
            "TNFRSF4",
            "TNFAIP3",
            "TRAF5",
            "PECAM1",
            "IFNG",
            "CCL24",
            "ETS1",
            "SKI",
            "ZAP70",
            "CAMP",
            "STING1",
            "IL1RL1",
            "NFKBIA",
            "SIGIRR",
            "TLR7",
            "IL23A",
            "PYCARD",
            "KLRF2"
        ],
        "Coefficient": [
            0.11593349760378022,
            -0.08902444332107762,
            0.08091691210894186,
            0.07668167000459082,
            -0.07581742929013773,
            0.07431672562262875,
            -0.0740304349722961,
            0.07257919320092836,
            0.06817690301608052,
            0.06754663257912967,
            -0.06697440948449204,
            0.06586286315988672,
            -0.0652689313861902,
            -0.06447689822232833,
            0.06433499607072984,
            0.0629038447103067,
            0.06261140209194233,
            -0.06223720670402955,
            -0.06150962130448277,
            -0.060442216038361654,
            0.05977548270322913,
            0.05835080205554876,
            -0.056857717254475755,
            0.05680162688579825,
            -0.05602314929737757,
            0.05601116939119595,
            -0.05560628813411803,
            -0.05481362751930846,
            0.054617031972584086,
            0.05435631579756797,
            -0.05417126687470663,
            -0.05392108795525891,
            -0.05357751752672325,
            0.05297480316876968,
            -0.05284981404168121,
            0.05259624978543704,
            0.0524267929451732,
            0.05228688429071715,
            0.051099861034540436,
            0.050332053553353316,
            0.05031576704216455,
            0.048878460728525516,
            0.04848185635669603,
            0.04823147678863348,
            0.046123148025607616,
            0.04580237870692568,
            0.04554203756038423,
            -0.0453475211631671,
            0.04532184754651135,
            -0.04503948129264331,
            -0.04503298553091863,
            -0.04489386640607669,
            0.04485443746682627,
            0.044731009663292035,
            0.0438035739418841,
            -0.043538614133580976,
            -0.04350245657928282,
            -0.04349988940690887,
            0.04339899264879226,
            -0.043379483530261984,
            0.042876195887061604,
            -0.04248958124073684,
            -0.04239599904827677,
            -0.042068787187870126,
            -0.04150025932368595,
            0.0412214978643104,
            -0.041119409566089254,
            0.04098669023541362,
            0.04058154402717685,
            0.040279542931632675,
            0.04027754348180495,
            -0.04022429696955051,
            -0.03994223506656705,
            0.03954050205954177,
            0.0394719180915318,
            0.03901398025978737,
            -0.03883383822012147,
            -0.03882129037533123,
            0.038501746612662605,
            0.03835329571236541,
            0.03826831753155028,
            0.037833349726787556,
            0.03760591331555461,
            0.03710149485014164,
            -0.037083659358536664,
            -0.036437220860086474,
            0.03636244426243808,
            -0.03635904168918728,
            0.0356498905886336,
            0.035449938564084654,
            0.035447406020265235,
            -0.035358404458732215,
            -0.0352152527536782,
            0.03468054422852331,
            -0.03461090877566838,
            0.03448907864064171,
            0.034143100167319126,
            -0.033878995495035404,
            0.03379018966322187,
            -0.033534914411902914,
            -0.033388673745070326,
            0.03335742892842936,
            -0.03331594418739948,
            0.03308934108669271,
            0.03295475186557044,
            0.032801661478191524,
            0.0327165596049127,
            -0.03265211676214367,
            -0.032599037293886926,
            -0.03259250345384989,
            -0.03256219979826365,
            -0.03200412738823635,
            -0.03199445751652058,
            0.03197915906131458,
            -0.0319297668768924,
            0.03189430099676336,
            0.03142033581429395,
            0.031290069751941235,
            -0.03126612969636622,
            0.030584196531649403,
            -0.030336285235639547,
            0.03026826807145595,
            -0.03025069848805359,
            0.030030274536268123,
            0.02980335988469922,
            -0.029796206044689955,
            -0.0297329541460324,
            -0.0292980716289972,
            -0.029291700457844603,
            0.028985121341200445,
            0.028904686470066585,
            -0.028726618919125726,
            0.028636086749877582,
            0.0285447707586412,
            0.02851522410358318,
            -0.028365141743973112,
            -0.02835183913834133,
            -0.028272699254995877,
            0.028106235361716927,
            -0.027883602122362634,
            0.02779883241554797,
            0.02760301875361424,
            0.02755086035707068,
            -0.026959376727912855,
            -0.026930309702674127,
            -0.026900047164339868,
            0.026862631207499436,
            -0.026862442688316973,
            -0.026860244754481923,
            -0.026737749929892963,
            0.026564766341156006,
            -0.026515401165056168,
            -0.026452260891907806,
            0.026387061354224257,
            -0.02638142617461828,
            -0.026351890538100286,
            -0.02634825401210634,
            0.026347624261204468,
            -0.026337020182028815,
            -0.026330215293461436,
            -0.026100976417815426,
            -0.026094703194311144,
            0.025979967595384255,
            0.025956851953684454,
            -0.02590138120433732,
            -0.025887938998234317,
            0.025863314664041865,
            -0.02570833773728257,
            -0.02559297208252486,
            -0.025543958332689597,
            0.02545162566482043,
            -0.025295848238550803,
            0.025183576002988144,
            0.02514051958630381,
            0.025074792865240128,
            -0.025059479619016303,
            -0.025005239438351166,
            -0.02472380368624237,
            -0.024447698365561397,
            0.024393626977651375,
            -0.024288806372352947,
            -0.024278835260954708,
            -0.02408975610885237,
            0.02400968887112815,
            0.023962867186647557,
            0.023720966207279846,
            0.02367938600691891,
            0.023646130494776447,
            0.023637299462913073,
            0.023375104075540734,
            0.023287748523728946,
            0.023271325930067723,
            -0.023229519581181017,
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            0.022932452829353724,
            -0.022778614232535372,
            0.022733355864066267,
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            -0.022665551684908383,
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            -0.022613804590159107,
            -0.022530492928546385,
            0.022519521698876593,
            -0.022297116280566655,
            0.022180276507175724,
            -0.022143072358165584,
            -0.022136878957960154,
            0.02210597549293756,
            -0.02207873515648125,
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            -0.0216138800404768,
            -0.02158063743131465,
            -0.021479062874100695,
            0.021440654939459895,
            -0.021288918279545127,
            -0.021255990227792558,
            -0.02121289750706858,
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            0.021130651616645506,
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            -0.02104337253080003,
            -0.020970532488810176,
            0.020917863032639834,
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            -0.02083287914411342,
            -0.02082421341423524,
            0.020759809939717423,
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            -0.020543874269269225,
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            -0.020377365069126813,
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            -0.02018675112598672,
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            -0.019917203728375053,
            -0.01957721231389032,
            -0.019575639398426204,
            0.019560485616081175,
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            -0.019317465655566288,
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            0.01902348429217463,
            0.01896167562480206,
            0.018859488715905894,
            0.018816444730264403,
            0.018737633507076527,
            -0.018617212147798375,
            0.018541084437465244,
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            -0.0184055780849129,
            -0.01834753198066843,
            -0.01832170536899905,
            0.018257382537717116,
            0.018241019488480937,
            0.018223633968743824,
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