{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "BCL2L11",
            "B3GAT1",
            "C1R",
            "C4BPA",
            "BCAP31",
            "BTK",
            "C1QB",
            "CD40LG",
            "APP",
            "DEFB4A",
            "CCL8",
            "CXCR3",
            "IRAK2",
            "BCL2",
            "HLA-DQA1",
            "EBI3",
            "LILRB5",
            "MAPK14",
            "ADGRE2",
            "CCL15",
            "CD59",
            "TLR3",
            "C3",
            "TP53",
            "EGR2",
            "BATF",
            "FADD",
            "CD9",
            "IL1R1",
            "HRAS",
            "HFE",
            "CIITA",
            "LTB4R",
            "FKBP5",
            "CD86",
            "CXCR2",
            "DEFB103A",
            "CR2",
            "PTGS2",
            "BST2",
            "CD53",
            "CCL20",
            "CCL3",
            "FYN",
            "CARD9",
            "PSMB5",
            "CCND3",
            "PTAFR",
            "BCL3",
            "CTNNB1",
            "DEFB103B",
            "IL4R",
            "IL7",
            "SLC2A1",
            "NFATC2",
            "ATG16L1",
            "S1PR1",
            "FCAR",
            "IKZF1",
            "KLRC3",
            "CCL5",
            "CCR8",
            "CRADD",
            "POLR1G",
            "MBP",
            "IGF2R",
            "NT5E",
            "CD14",
            "CCL22",
            "MALT1",
            "IRGM",
            "IL6",
            "MAPKAPK2",
            "FN1",
            "FAS",
            "CFI",
            "IRF7",
            "IL17A",
            "ATG12",
            "TNFSF11",
            "CFH",
            "CD160",
            "LTB4R2",
            "CXCL11",
            "CD80",
            "CCRL2",
            "AIRE",
            "CD46",
            "ABL1",
            "FOXP3",
            "CCL13",
            "CD79B",
            "LCP2",
            "ACKR4",
            "CCL2",
            "ITGA5",
            "KLRA1P",
            "CD19",
            "NOTCH2",
            "RAG2",
            "FCER1A",
            "HLA-DRB3",
            "DEFB1",
            "SPP1",
            "IL22",
            "MUC1",
            "PSMC2",
            "CFD",
            "NOD2",
            "CD36",
            "FCGR2B",
            "CCL19",
            "ATG10",
            "LIF",
            "NLRP3",
            "SELPLG",
            "MAP4K4",
            "SELE",
            "IL13RA1",
            "PDCD1",
            "IL1RAP",
            "EGR1",
            "ZBTB16",
            "MX1",
            "ATG7",
            "GZMK",
            "IL10",
            "IL4",
            "EDNRB",
            "IL16",
            "IL32",
            "IL21R",
            "CFB",
            "IL1B",
            "CUL9",
            "BCL10",
            "BLNK",
            "BTLA",
            "CD1D",
            "IL21",
            "CD7",
            "TNFSF15",
            "STAT4",
            "CD4",
            "GP1BB",
            "MSR1",
            "POU2F2",
            "CSF2",
            "SLAMF6",
            "TLR4",
            "CD274",
            "IFI16",
            "AICDA",
            "ITLN2",
            "PDCD2",
            "IL1RN",
            "KCNJ2",
            "CLEC5A",
            "ITGA2B",
            "TIRAP",
            "IL26",
            "ITGB1",
            "TCF7",
            "BAX",
            "IL7R",
            "TNFSF8",
            "TOLLIP",
            "CD48",
            "TNFSF13B",
            "CD70",
            "CD1A",
            "IRF5",
            "CLEC6A",
            "IRF3",
            "TNFRSF17",
            "SLAMF1",
            "ITGA4",
            "KLRG1",
            "IL2RA",
            "CXCL8",
            "CCL16",
            "CCR6",
            "TGFBI",
            "CCR1",
            "PDCD1LG2",
            "RAG1",
            "IL3",
            "IFI35",
            "CX3CR1",
            "MAPK11",
            "CLU",
            "CCR2",
            "CTSC",
            "CCL4",
            "HLA-C",
            "MME",
            "CXCL1",
            "TAPBP",
            "CASP8",
            "IFNA2",
            "TRAF1",
            "IRAK1",
            "IRF4",
            "PAX5",
            "PRKCD",
            "CD163",
            "HLA-DMB",
            "UBE2L3",
            "LCK",
            "TLR1",
            "PTPN2",
            "IRAK4",
            "TNFRSF10C",
            "B2M",
            "CCR10",
            "MIF",
            "CCL26",
            "TAGAP",
            "IL12B",
            "HAVCR2",
            "C5",
            "CASP10",
            "CXCR6",
            "NCAM1",
            "CD8B",
            "IL6R",
            "CD58",
            "KLRG2",
            "MS4A1",
            "ENTPD1",
            "TCF4",
            "ARHGDIB",
            "PSMB7",
            "MYD88",
            "CD96",
            "CDKN1A",
            "CD164",
            "IL10RA",
            "IL15",
            "IFNL1",
            "CLEC4E",
            "ITGAL",
            "IKBKE",
            "ITGB2",
            "PLA2G2E",
            "TRAF4",
            "CCL23",
            "STAT1",
            "CD8A",
            "C1QA",
            "STAT3",
            "ICAM3",
            "BST1",
            "PML",
            "NFATC1",
            "TLR9",
            "ICAM1",
            "TLR2",
            "TNFSF12",
            "CEACAM6",
            "IL2RG",
            "CD99",
            "ADA",
            "IL27",
            "CXCL12",
            "CD28",
            "HLA-DPA1",
            "RELB",
            "CD276",
            "PLAU",
            "CSF1",
            "IFNAR1",
            "CSF2RB",
            "STAT5A",
            "IFIH1",
            "PDGFB",
            "PTGER4",
            "SMAD5",
            "SYK",
            "CXCL2",
            "MRC1",
            "C6",
            "IL6ST",
            "IFNB1",
            "TNFRSF9",
            "KLRB1",
            "TGFBR1",
            "XCL1",
            "ITGAM",
            "TLR5",
            "CD34",
            "CD74",
            "CD81",
            "PRDM1",
            "LILRB2",
            "CR1",
            "CCL11",
            "VCAM1",
            "NOTCH1",
            "C7",
            "IL2RB",
            "CD40",
            "IL17F",
            "CEBPB",
            "S100A8",
            "KIR3DL1",
            "KLRC1",
            "C1QBP",
            "NFKBIZ",
            "CD55",
            "IL20",
            "HAMP",
            "PSMD7",
            "IKBKB",
            "GATA3",
            "PLAUR",
            "FCGRT",
            "PDGFRB",
            "JAK3",
            "TLR8",
            "LAIR1",
            "LITAF",
            "CD2",
            "C1S",
            "CD3D",
            "HLA-A",
            "IL11RA",
            "TNFRSF1B",
            "FCGR2A",
            "THY1",
            "RTRAF",
            "IL5",
            "TRAF6",
            "IL1RL2",
            "XCR1",
            "ARG2",
            "CCL18",
            "IL18",
            "NCF4",
            "PRF1",
            "TNFRSF11A",
            "AHR",
            "IRAK3",
            "LAG3",
            "MR1",
            "CCR5",
            "CD83",
            "KIT",
            "CX3CL1",
            "SOCS3",
            "SERPING1",
            "LILRA6",
            "BCL6",
            "TBK1",
            "HLA-DPB1",
            "BID",
            "KLRF1",
            "GBP5",
            "LILRA1",
            "NFKB2",
            "GPI",
            "CD6",
            "TGFBR2",
            "LTA",
            "CASP2",
            "NOD1",
            "TNFSF4",
            "HLA-DOB",
            "ELP1",
            "TFRC",
            "GBP1",
            "IL23R",
            "ITGA6",
            "IFNL2",
            "ABCB1",
            "ARG1",
            "CCL7",
            "STAT6",
            "ICOS",
            "KIR3DL3",
            "C9",
            "TYK2",
            "CSF3R",
            "IFIT2",
            "CMKLR1",
            "IL12A",
            "MAF",
            "ITGAE",
            "LY96",
            "TNFRSF13B",
            "CYBB",
            "NOS2",
            "LILRB1",
            "LAMP3",
            "HLA-B",
            "IFNGR1",
            "CXCL13",
            "CEACAM8",
            "CLEC7A",
            "ICOSLG",
            "ICAM5",
            "SOCS1",
            "PSMB9",
            "TNFRSF8",
            "MAPK1",
            "CD244",
            "IKZF3",
            "CD247",
            "CD24",
            "IKZF2",
            "IL9",
            "IRF8",
            "ATM",
            "ILF3",
            "TAP2",
            "RUNX1",
            "PIGR",
            "TNF",
            "PTPN6",
            "CD5",
            "TIGIT",
            "PLAAT4",
            "MASP1",
            "LGALS3",
            "CD79A",
            "CD82",
            "HLA-DMA",
            "IL18RAP",
            "NCR1",
            "IRF1",
            "CDH5",
            "TNFRSF14",
            "IDO1",
            "HLA-DRB1",
            "CD27",
            "PTPN22",
            "CHUK",
            "CASP3",
            "DUSP4",
            "LILRA3",
            "CFP",
            "LTF",
            "LTBR",
            "RAF1",
            "IL13",
            "CD44",
            "GZMB",
            "HLA-DQB1",
            "PTK2",
            "MASP2",
            "RORC",
            "STAT5B",
            "LEF1",
            "PPARG",
            "XBP1",
            "TRAF3",
            "DPP4",
            "JAK1",
            "CSF1R",
            "C2",
            "SLAMF7",
            "ITGAX",
            "TNFSF10",
            "KLRC4",
            "TRAF2",
            "IL18R1",
            "LILRB3",
            "KLRC2",
            "HLA-DRA",
            "CTSG",
            "LILRA5",
            "GNLY",
            "IL19",
            "CLEC4A",
            "ICAM4",
            "CISH",
            "NFATC3",
            "ICAM2",
            "LILRA2",
            "CEACAM1",
            "ZEB1",
            "TICAM1",
            "CASP1",
            "MBL2",
            "TAL1",
            "TAP1",
            "IL1A",
            "IL1R2",
            "SH2D1A",
            "IFITM1",
            "VTN",
            "KIR3DL2",
            "IL12RB1",
            "GFI1",
            "CXCR4",
            "SRC",
            "KLRD1",
            "CXCL10",
            "LILRA4",
            "C8A",
            "IL17B",
            "GZMA",
            "NFIL3",
            "PPBP",
            "CTSS",
            "TNFAIP6",
            "LILRB4",
            "IFNG",
            "FCER1G",
            "CD22",
            "TNFAIP3",
            "CD3E",
            "JAK2",
            "ITLN1",
            "CD209",
            "S100A9",
            "CCL24",
            "CXCR1",
            "RELA",
            "PLA2G2A",
            "KLRK1",
            "MAP4K1",
            "MCL1",
            "SMAD3",
            "MARCO",
            "MAP4K2",
            "IL22RA2",
            "EOMES",
            "PSMB10",
            "SELL",
            "TGFB1",
            "STAT2",
            "IL2",
            "C8B",
            "CXCL9",
            "PSMB8",
            "IL1RL1",
            "NFKB1",
            "PECAM1",
            "NFKBIA",
            "SKI",
            "GPR183",
            "TRAF5",
            "CAMP",
            "SIGIRR",
            "IKBKG",
            "TNFRSF13C",
            "ZAP70",
            "IFNAR2",
            "CCR7",
            "TLR7",
            "ETS1",
            "TBX21",
            "TNFRSF4",
            "IL23A",
            "PYCARD",
            "C8G",
            "KLRF2",
            "STING1"
        ],
        "Coefficient": [
            0.11817054419392771,
            -0.08746696026433824,
            0.07957770774442328,
            0.0765864407199859,
            0.07587924389494559,
            -0.07404507592359916,
            0.07338480450172058,
            -0.07254010015911079,
            0.06958805837018267,
            0.06912285846227673,
            0.06750632487922038,
            -0.06556915047800135,
            -0.06526262337099975,
            0.065002637642608,
            -0.06312110266000938,
            0.0628423901911868,
            0.06273496515390849,
            0.06220328003376878,
            -0.06037200001954447,
            -0.059503030928792805,
            -0.058616472816963125,
            0.057846117032398184,
            -0.05752192403706941,
            0.05661542093283926,
            0.05650361776542779,
            -0.056167693067110294,
            -0.05558225898136908,
            0.05534532826134243,
            -0.055341724954956394,
            -0.05472415162789268,
            0.05466115655775712,
            0.05418901020233382,
            -0.053684484713428834,
            0.05242759935580247,
            0.05216723604327051,
            -0.05199207756084621,
            -0.0515121504844912,
            0.05135279858330882,
            0.05120733767903941,
            0.05074579815538795,
            0.05012746548521059,
            0.04953794370877181,
            0.04934335368820751,
            -0.04863157534470178,
            -0.047368153909110686,
            0.046757712136932535,
            -0.04602324245902902,
            0.04589013419639442,
            0.04586431466676228,
            0.045808133217546634,
            -0.04562199530281307,
            -0.04528488017914582,
            0.04511604719487731,
            0.044355911348707325,
            -0.04431245258109294,
            0.04406004895845916,
            -0.04345755225499237,
            -0.043407178142454046,
            -0.04320425948404729,
            -0.042978084971158445,
            -0.04290649292523044,
            0.04261507169192748,
            0.042564929815310404,
            0.0420722152310882,
            -0.04206293619731492,
            0.04198752794676291,
            -0.04194170482775354,
            -0.03962406365628502,
            0.038994998049623815,
            0.0387782695254544,
            0.03839620040405021,
            -0.038385557812412645,
            0.038381249811493295,
            0.038354718311316385,
            0.038340758293553004,
            0.038320813590355995,
            0.03803107717287327,
            0.03749119731301908,
            0.037486690228795645,
            -0.03748468140653688,
            0.037347191318270336,
            -0.03721868120125707,
            0.03720944349069665,
            0.0368384599477123,
            0.03676214196824216,
            -0.03670790572692726,
            -0.03668854608436631,
            0.03643393765451052,
            -0.036376511760621996,
            -0.0363406761064482,
            -0.036215343360660804,
            -0.03615485759345988,
            -0.03611865700805649,
            -0.035910726123730134,
            -0.03559741477314062,
            0.03534900472521065,
            0.034886103492695206,
            0.03461185739897062,
            0.03456369129327055,
            0.03453705117703082,
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            -0.033929432235701606,
            -0.03361830177156151,
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            -0.033413824307258394,
            0.03322607254604586,
            0.033017995410709135,
            -0.03282358067368384,
            -0.03259102044723354,
            0.03258781663806084,
            -0.03205801432504202,
            -0.031968423199979674,
            -0.03172049136842918,
            0.031683459011263335,
            0.031647244030983186,
            0.031539229998207415,
            -0.03149991203498245,
            0.031481192986493836,
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            -0.03100763335738287,
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            -0.030850186651828197,
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            -0.03016768387964764,
            0.029822463433380596,
            0.029576287562417303,
            -0.029507119670226067,
            -0.029058224660329722,
            0.02894124219487441,
            0.028794910439788955,
            0.02875113780912863,
            0.028731308374083227,
            0.028347643678635525,
            -0.028322001601793947,
            -0.028207251958799202,
            0.02811410312220626,
            -0.028057110143344065,
            0.027985333285241068,
            -0.027763305431743105,
            0.02776246838939903,
            -0.02768094096812774,
            -0.027660093537691423,
            0.02713542577211086,
            -0.0270772665353178,
            -0.02703928436785126,
            -0.02685365043846254,
            -0.026851519286492497,
            -0.02681659965382751,
            0.02652236454785007,
            0.02646938958219883,
            -0.02641811231244309,
            -0.026380481305066098,
            0.026285140661995065,
            -0.02624403879024943,
            -0.026181831035516,
            -0.025919366221047825,
            0.025792245973174976,
            -0.025786469207289525,
            -0.025786102107845953,
            0.025700415238560936,
            -0.025682790486058007,
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            0.02565022213496777,
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            0.025625709392704733,
            -0.02562290637801812,
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            -0.025465559755765088,
            -0.024911079218953327,
            0.02480458419623145,
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            -0.024291821685840948,
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            0.023813625716058908,
            0.02379387926159674,
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            0.023530280743228,
            -0.02337260107248635,
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            0.018139202503472594,
            0.018071055771772288,
            0.017947043501840364,
            0.017864838945401064,
            0.01783564839679424,
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