{
    "significant_genes": {
        "Variable": [
            "DYM",
            "RIC8A",
            "CCDC47",
            "TNNI3",
            "TIAM2",
            "VGLL2",
            "ZNF444",
            "CHMP5",
            "FRS2",
            "SULT1C3",
            "MCFD2",
            "C9orf5",
            "C8orf56",
            "HIST1H2BI",
            "FLJ46111",
            "FGF2",
            "MGAT3",
            "TOPORS",
            "C3orf51",
            "LHX1",
            "FSD2",
            "DNAJC27",
            "HERPUD2",
            "LOC84856",
            "RTN2",
            "ARL5A",
            "EEF2",
            "PADI2",
            "IGHMBP2",
            "LY6G6C",
            "OR10AG1",
            "ZNF167",
            "MTNR1B",
            "OR5D18",
            "ARSA",
            "CCDC52",
            "IGFBP1",
            "PYGO1",
            "NUAK2",
            "DEM1",
            "DPCD",
            "TXNDC17",
            "ERF",
            "ODZ2",
            "MORC1",
            "CDC14C",
            "ZAR1",
            "FATE1",
            "RESP18",
            "C1orf53",
            "TRHR",
            "BEND6",
            "UPF0639",
            "DAB1",
            "OSR2",
            "ADCK4",
            "SNORA15",
            "ATRIP",
            "DPY19L2P4",
            "SERPINB9",
            "LOC651250",
            "CA9",
            "CLIC6",
            "RFPL3",
            "OR52N5",
            "C21orf29",
            "UNC93A",
            "MBD3L2",
            "LANCL2",
            "C2orf14",
            "H2AFY",
            "NQO2",
            "FTHL17",
            "LLPH",
            "C6orf72",
            "LAT",
            "C1QTNF9",
            "KRTAP5-9",
            "MYH7B",
            "ADIPOR2",
            "FAM157A",
            "OPN3",
            "NANOS1",
            "RHOU",
            "LOC157627",
            "USP29",
            "FAM155A",
            "NLRP4",
            "PNLIPRP2",
            "ANKRD32",
            "ARHGAP10",
            "ZSCAN5B",
            "C7orf49",
            "KIAA0776",
            "SLN",
            "ZNRF1",
            "TMEM14E",
            "AMAC1L2",
            "SP9",
            "AKIRIN1",
            "ACSM4",
            "OR56A4",
            "OR4S2",
            "FAM21A",
            "RPSAP52",
            "DUSP13",
            "RAP1GAP2",
            "GTF2H2C",
            "TBCC",
            "CARTPT",
            "ZNF502",
            "NMB",
            "OR6C3",
            "PPIAL4E",
            "SERPIND1",
            "MID2",
            "ACTL7A",
            "KCNK18",
            "TCF23",
            "TFAP2D",
            "DUSP23",
            "C14orf145",
            "IRGM",
            "TUBB8",
            "TPCN2",
            "MED13",
            "MAGEB1",
            "CABP5",
            "PAQR9",
            "GLRA4",
            "CD1B",
            "CNOT4",
            "OR52E2",
            "TSSC4",
            "ZSCAN5A",
            "ATAD3B",
            "HIST1H3F",
            "ROBO3",
            "CYP26C1",
            "RPE",
            "SLC22A16",
            "OR5H6",
            "TMEM59L",
            "RHBG",
            "CSRP2BP",
            "SCARNA23",
            "IGFN1",
            "C1orf201",
            "USP50",
            "POLDIP3",
            "SNORA62",
            "LOC100131691",
            "LAIR2",
            "OLIG3",
            "C2orf39",
            "CYP4F8",
            "TAF7L",
            "PTCHD3",
            "IL12B",
            "ZNF605",
            "DISC1",
            "NPB",
            "C15orf43",
            "LOC100131496",
            "TRIM6-TRIM34",
            "LOC100192379",
            "DCAF12L1",
            "BRD7P3",
            "OPN1MW",
            "FAM110A",
            "ASB11",
            "ZNF491",
            "DEFB109P1B",
            "DACH2",
            "C4orf11",
            "RHCE",
            "LOC407835",
            "TBC1D3P2",
            "HSFX2",
            "ODF4",
            "FAM92A1",
            "MFGE8",
            "LOC286094",
            "STAG3L4",
            "FKBP1AP1",
            "PGA5",
            "SHKBP1",
            "FAM78B",
            "CELA2A",
            "URGCP",
            "EIF4E1B",
            "AKR1C4",
            "FLJ39582",
            "NANOG",
            "KLK3",
            "SLC22A25",
            "PROKR1",
            "CDH12",
            "BTN2A3",
            "OR6W1P",
            "ABCG1",
            "THRB",
            "TPD52L3",
            "PRAMEF8",
            "RBM46",
            "WDR61",
            "MET",
            "C22orf42",
            "PRKCG",
            "PCDHB15",
            "NDUFAF4",
            "UTP11L",
            "FTCD",
            "MMP17",
            "C12orf40",
            "LCT",
            "LGALS13",
            "PDYN",
            "MIP",
            "STRA8",
            "XKR9",
            "CRLF1",
            "PIH1D1",
            "CLRN2",
            "PAGE1",
            "CBWD5",
            "CMYA5",
            "PCDHGB2",
            "DDI1",
            "CADM2",
            "MS4A13",
            "ZNF586",
            "TAF8",
            "CETN1",
            "LOC100132288",
            "ZNF717",
            "C3orf23",
            "LHX3",
            "DEXI",
            "SLC32A1",
            "LECT1",
            "PGLYRP3",
            "ZCCHC12",
            "C1orf128",
            "ZCCHC13",
            "MAG",
            "ZNF648",
            "UGT2B11",
            "OR8A1",
            "CLLU1OS",
            "HIST1H2BB",
            "FAM59A",
            "TREX1",
            "ALMS1P",
            "PLSCR2",
            "MPZ",
            "SLC44A2",
            "PRKAG3",
            "C4orf27",
            "SYCP3",
            "SLC13A4",
            "RBMY1J",
            "KLHL10",
            "TRY6",
            "FAM71F2",
            "OCA2",
            "STK32A",
            "LYZL6",
            "LIM2",
            "GDNF",
            "HRNBP3",
            "TTN",
            "KRT39",
            "PKDREJ",
            "MKKS",
            "HBZ",
            "PSORS1C1",
            "NXNL2",
            "ZNF606",
            "RP1L1",
            "SAR1A",
            "TAS2R19",
            "SERPINA9",
            "BCL2L15",
            "MASP1",
            "CRYZ",
            "MAPK10",
            "PRSS53",
            "TAC4",
            "DYRK1B",
            "SNORA67",
            "LOC100134368",
            "SNORA5A",
            "ANKRD42",
            "PRTN3",
            "ZCCHC4",
            "PCDHA2",
            "GJB7",
            "GCK",
            "EPS15L1",
            "RNASE10",
            "ZNF784",
            "ZNF471",
            "SUSD3",
            "C22orf24",
            "ALG11",
            "ID2B",
            "CETN4P",
            "PRKRIR",
            "CT47A7",
            "OLIG2",
            "LOC100129534",
            "SLC17A7",
            "EDDM3B",
            "YIPF7",
            "LOC154822",
            "OR10Q1",
            "C5",
            "BZRAP1",
            "LOC100133957",
            "MAGEA4",
            "ATP5A1",
            "NKPD1",
            "DCAF4L1",
            "TEAD2",
            "TMEM179",
            "DKFZp686A1627",
            "PROK1",
            "PLD3",
            "PIWIL1",
            "KAAG1",
            "ADAM29",
            "SLC20A1",
            "KRT36",
            "CH25H",
            "BRCC3",
            "FAM194A",
            "MTIF2",
            "MAP6D1",
            "RINL",
            "OR2T4",
            "NCRNA00110",
            "TP53TG5",
            "FER1L6",
            "DSCR4",
            "SPEM1",
            "ACO2",
            "ZNF649",
            "IMMT",
            "ATP5L2",
            "ERN1",
            "BRD7",
            "HELB",
            "CCNDBP1",
            "MBD3L5",
            "MEPE",
            "PRKD2",
            "FLJ42393",
            "DNAJA1",
            "SYNGR1",
            "FBXO41",
            "XYLT1",
            "TBC1D3G",
            "FAM75A6",
            "LOC391322",
            "PEPD",
            "CRYGB",
            "TRPV1",
            "SNORA71C",
            "SLC23A2",
            "LMBR1L",
            "SLC22A14",
            "TUBAL3",
            "TTTY1B",
            "PLCXD2",
            "ARMS2",
            "RTP1",
            "TUSC5",
            "PUM2",
            "IL17F",
            "GUSBP1",
            "PADI6",
            "PIGB",
            "BTN3A2",
            "ZNF252",
            "LOC402644",
            "EPX",
            "C2CD2",
            "NCRNA00174",
            "UBP1",
            "UBTFL1",
            "DEFB108B",
            "ZNF114",
            "HOXB3",
            "OPRM1",
            "OSM",
            "IL6",
            "TFAP2B",
            "KIF16B",
            "PAAF1",
            "RGPD8",
            "WFDC10B",
            "IPMK",
            "WDR76",
            "AGXT",
            "GPR97",
            "PPP1R7",
            "PDZD9",
            "SMR3A",
            "TMEM120A",
            "NCRNA00160",
            "DAOA",
            "TMPPE",
            "ACSBG2",
            "KRCC1",
            "MT1DP",
            "PGPEP1L",
            "GRXCR2",
            "FAM71A",
            "CFHR1",
            "RALYL",
            "OR2K2",
            "CDRT15",
            "LOC340508",
            "RFXANK",
            "PSD2",
            "DGAT2",
            "ARHGEF9",
            "SHQ1",
            "FAM71F1",
            "LOC728819",
            "OR2T10",
            "SIAH1",
            "TCTN2",
            "DGCR9",
            "RPL23AP32",
            "F2",
            "OR5K1",
            "DGAT2L6",
            "C16orf88",
            "KATNAL2",
            "HSPC157",
            "HAO1",
            "TAS2R30",
            "GPR78",
            "LHX8",
            "OR1L8",
            "MAS1",
            "SNORA14A",
            "PRKD3",
            "ANGPTL3",
            "C9orf79",
            "HLA-J",
            "DGCR10",
            "TSPAN16",
            "OR4D2",
            "KLHL34",
            "IFNW1",
            "C2orf61",
            "HOMEZ",
            "FAM182A",
            "MESP2",
            "SPG21",
            "LOC285696",
            "SPACA4",
            "FOXD4L5",
            "FAM178B",
            "SNORA41",
            "ITPKC",
            "HAND2",
            "NAP1L4",
            "LOC127841",
            "NAA30",
            "SPINT4",
            "GRIA3",
            "PTPLA",
            "RNU4ATAC",
            "FSHR",
            "TTTY20",
            "VPS24",
            "CMTM6",
            "ANP32A",
            "EIF3L",
            "MGC12982",
            "FOXJ3",
            "SMR3B",
            "DNAJC22",
            "SUMO4",
            "CD99",
            "C3orf49",
            "C5orf40",
            "PRSS41",
            "TMEM189-UBE2V1",
            "PCDHA1",
            "KCTD8",
            "LOC254312",
            "AADACL2",
            "SNORA69",
            "LAMP2",
            "SVOPL",
            "KRT23",
            "NUBP1",
            "RBMXL2",
            "C20orf123",
            "GOLGA6C",
            "MRPS17",
            "CNTN3",
            "HESX1",
            "C14orf39",
            "TTTY2",
            "LRRC24",
            "TRPM4",
            "WDR35",
            "STON1-GTF2A1L",
            "VN1R2",
            "FOLR3",
            "C20orf166",
            "SLC31A1",
            "LOC253039",
            "IQCA1",
            "ALDH8A1",
            "ZNF577",
            "WWP1",
            "USP26",
            "HBD",
            "LOC100130264",
            "MAGEB10",
            "CLTCL1",
            "ANKRA2",
            "CCL20",
            "GSG1L",
            "ATG7",
            "HAPLN4",
            "SFRS12",
            "B4GALT1",
            "?|442388",
            "DEFA6",
            "FSTL5",
            "LOC643763",
            "TEKT5",
            "PRSS33",
            "DDX1",
            "BCL7C",
            "OR3A1",
            "SPATA22",
            "CCDC110",
            "LOC221710",
            "RNASE12",
            "SPANXN5",
            "LOC339524",
            "CALHM1",
            "PCDHB11",
            "TCF7L2",
            "DGKD",
            "CTXN3",
            "CYP2A6",
            "AP3M2",
            "KRTAP10-10",
            "MATK",
            "OR6A2",
            "?|388795",
            "LOC441601",
            "SETMAR",
            "ZNF540",
            "WASH5P",
            "NBPF16",
            "CHRNE",
            "CCNA1",
            "NR1I3",
            "SLC17A1",
            "SNORA32",
            "WNT6",
            "MDS2",
            "PRAMEF13",
            "FAM21B",
            "TCEB3B",
            "LOC283332",
            "KCNE4",
            "HILS1",
            "C3orf20",
            "IGSF22",
            "TRPM6",
            "AQP12B",
            "AIPL1",
            "MLEC",
            "DSCR8",
            "PKD2L1",
            "GHRLOS",
            "CCKBR",
            "SNORA49",
            "CACNG7",
            "ORM1",
            "BMS1P4",
            "MC3R",
            "CRYGA",
            "FAM170A",
            "VN1R5",
            "C2orf67",
            "CPXCR1",
            "LOC116437",
            "MED20",
            "CDH17",
            "SDC4P",
            "TMEM135",
            "RPS26P11",
            "LOC168474",
            "HS3ST3B1",
            "RCL1",
            "VAPB",
            "BMP10",
            "DYTN",
            "SPATA19",
            "FAM166A",
            "KCNV1",
            "FAM149A",
            "TMEM97",
            "TRPC1",
            "SEC63",
            "CT62",
            "C12orf72",
            "ADO",
            "SLC25A32",
            "BCYRN1",
            "DAZ2",
            "C3orf79",
            "LOC285501",
            "BASE",
            "GAGE10",
            "GOLGA6D",
            "CTSL3",
            "ZNF16",
            "XCR1",
            "CGB1",
            "ZNF705A",
            "PLIN1",
            "CXCL14",
            "TTC3",
            "NDRG3",
            "IKBKG",
            "UGT2A3",
            "C1orf68",
            "LOC158696",
            "C9orf6",
            "OSBP",
            "SNORD23",
            "ANKFN1",
            "ZNHIT2",
            "TULP2",
            "WDR77",
            "RGSL1",
            "FTSJ2",
            "PTPN20A",
            "PFN3",
            "SNORA3",
            "GPR152",
            "CCDC116",
            "SEBOX",
            "ACSS2",
            "TTTY22",
            "IL1RL2",
            "NF1P1",
            "MAT1A",
            "PFKFB2",
            "KRTAP23-1",
            "SNORD116-19",
            "RMND1",
            "SNORA34",
            "PCDHGA4",
            "CCDC15",
            "C5orf60",
            "SNORD103A",
            "SNORD124",
            "SNORD88C",
            "CCDC115",
            "SPINT3",
            "EMILIN3",
            "BLVRA",
            "LOC441455",
            "CDK13",
            "GPR45",
            "CASP5",
            "TTTY21",
            "C1orf227",
            "SNORD88B",
            "ZACN",
            "GFAP",
            "SLC25A21",
            "PRR20B",
            "TTTY19",
            "TTTY13",
            "ZDHHC4",
            "CT47A11",
            "C18orf2",
            "DEFB114",
            "SNORD8",
            "PRR20A",
            "HBA2",
            "SNAR-A3",
            "SNORA30",
            "KRTAP19-2",
            "SNORD16",
            "PPIAL4B",
            "DEFB112",
            "PRR20D",
            "DEFB113"
        ],
        "Coefficient": [
            -3.9951976168919465,
            3.9493077640272687,
            -3.397610876138912,
            3.204787377163511,
            -3.1969669004595778,
            2.5708521816887737,
            2.474480827747049,
            2.403991370403385,
            2.2544539214985306,
            2.202630220145234,
            -2.151866762599797,
            -2.143283882118355,
            2.1372106603856977,
            -2.13651887509493,
            -2.0765288508114264,
            -2.0316437280016477,
            -1.9925120578112026,
            1.847428567752477,
            -1.8368764559700927,
            1.826632780990065,
            1.8144299583037709,
            -1.8094497466949804,
            1.7984472735915136,
            -1.7810217067179146,
            1.774641029988646,
            -1.7690593611042869,
            -1.7630777893846776,
            -1.7545907375105676,
            1.7323813086221371,
            -1.7095146654407662,
            1.6805020796710435,
            1.6466198636325908,
            -1.6425701000767259,
            -1.637306530245993,
            -1.6357695126256224,
            1.626332500580838,
            -1.6200396793072922,
            -1.6163688539247125,
            1.6129563899735355,
            1.5534762276696723,
            1.5137990777814008,
            1.4921188330080255,
            1.4756563463193213,
            1.4570343336194531,
            -1.426845037355447,
            -1.4232494053493414,
            -1.3961467397327372,
            1.3956736863073698,
            -1.3775268205161542,
            1.3585567880067952,
            -1.3343027282034552,
            1.325919113928738,
            -1.3089812995609045,
            -1.3076222841680458,
            -1.3056529352673527,
            1.2953891267323778,
            1.2874938446408164,
            1.2793880451787605,
            -1.2733154232806965,
            -1.2698652481868162,
            -1.2662450035283273,
            1.2653028320772817,
            1.2521946759654363,
            -1.250049405462633,
            1.2497944648815131,
            1.2366385271954659,
            -1.2261331518500045,
            1.2250361420258546,
            -1.2117424827921939,
            -1.2095288502792194,
            1.2025744948147707,
            1.1687871100189369,
            1.1653785530015452,
            1.160422922660225,
            -1.1547868993810069,
            1.146287264067815,
            -1.1400646063989601,
            1.1390005249248456,
            -1.1368823707604376,
            -1.1363159250242516,
            1.1359083508434011,
            1.130753575198242,
            1.1284625662564491,
            -1.1218129949062459,
            1.1149501002906748,
            1.0915323137076551,
            -1.0852153587162425,
            -1.0719055410972702,
            1.0579620119023185,
            1.0567684829636486,
            1.0563434258283542,
            1.047883303474928,
            1.0445853268754917,
            -1.0436962511278711,
            1.0394044057292484,
            1.0298892121809995,
            -1.0154678080367168,
            1.0142080353931542,
            -1.014022064028371,
            -1.0036323568815628,
            -0.9991231084788854,
            0.9989792757545211,
            -0.9869626490681287,
            0.9744749973767368,
            0.973053002008941,
            -0.9706341822543418,
            -0.9623464394336915,
            0.9475846906090187,
            0.9407458583808814,
            0.9296720566850061,
            0.9283178522288974,
            0.9273371040622843,
            -0.927119744788248,
            -0.9244374068035914,
            0.922199977950633,
            -0.9178582006208295,
            0.9144768052586291,
            0.9029005536948911,
            -0.8894215455359913,
            0.8836927686383105,
            0.8825774869570887,
            0.8799244591539237,
            0.8706938579678707,
            0.8696492149003748,
            0.8685880359781033,
            -0.8670493020047334,
            0.8643634499033667,
            -0.8632729541427107,
            0.8626976817749277,
            0.8606197087403706,
            -0.8594677807425607,
            0.8566230242410766,
            0.8472296127750127,
            0.846933056605779,
            0.8449002923205349,
            0.8321841761034966,
            -0.8257703017980635,
            0.8244303988554423,
            0.8232851569244696,
            0.8224654779532246,
            -0.8198980034912844,
            0.8149273932147334,
            0.813089448559959,
            0.8011886101519037,
            -0.800741959466438,
            0.7995977608698303,
            -0.7991678168203235,
            0.7964785527284082,
            -0.7932926640770526,
            -0.7887326658050079,
            0.788657249818954,
            0.7848531810353045,
            -0.7762302166614442,
            0.7673940028242513,
            -0.7616593122208214,
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