{
    "significant_genes": {
        "Variable": [
            "ATG5",
            "BATF3",
            "B3GAT1",
            "BCL2L11",
            "BTK",
            "C1R",
            "C4BPA",
            "C1QB",
            "CD40LG",
            "BCAP31",
            "CCL8",
            "DEFB4A",
            "CXCR3",
            "BCL2",
            "APP",
            "IRAK2",
            "HLA-DQA1",
            "EBI3",
            "ADGRE2",
            "CD59",
            "LILRB5",
            "MAPK14",
            "TLR3",
            "TP53",
            "CCL15",
            "BATF",
            "C3",
            "CIITA",
            "FADD",
            "IL1R1",
            "HRAS",
            "FKBP5",
            "EGR2",
            "CD9",
            "HFE",
            "DEFB103A",
            "PTGS2",
            "CD53",
            "LTB4R",
            "CD86",
            "CCL20",
            "ATG16L1",
            "CR2",
            "CXCR2",
            "PSMB5",
            "BCL3",
            "CTNNB1",
            "CCL3",
            "CCND3",
            "BST2",
            "CARD9",
            "PTAFR",
            "IL4R",
            "SLC2A1",
            "FYN",
            "DEFB103B",
            "IL7",
            "MBP",
            "S1PR1",
            "POLR1G",
            "NFATC2",
            "CCL5",
            "CCL22",
            "IKZF1",
            "FCAR",
            "AIRE",
            "IGF2R",
            "KLRC3",
            "CRADD",
            "MAPKAPK2",
            "CXCL11",
            "IL6",
            "CD46",
            "TNFSF11",
            "IRGM",
            "CD14",
            "CFI",
            "CCR8",
            "CFH",
            "CCRL2",
            "NT5E",
            "CCL2",
            "LTB4R2",
            "FAS",
            "HLA-DRB3",
            "FN1",
            "CD160",
            "MALT1",
            "CCL13",
            "CD80",
            "ABL1",
            "IL17A",
            "LCP2",
            "NOTCH2",
            "IRF7",
            "IL22",
            "RAG2",
            "ATG12",
            "IL13RA1",
            "ITGA5",
            "CD19",
            "FCER1A",
            "CD79B",
            "SPP1",
            "ACKR4",
            "KLRA1P",
            "SELE",
            "DEFB1",
            "ATG10",
            "PSMC2",
            "FCGR2B",
            "PDCD1",
            "CFD",
            "IL16",
            "LIF",
            "MUC1",
            "CFB",
            "NOD2",
            "IL1RAP",
            "ATG7",
            "CD36",
            "SELPLG",
            "FOXP3",
            "NLRP3",
            "EGR1",
            "CCL19",
            "IL32",
            "MAP4K4",
            "MX1",
            "ZBTB16",
            "IL10",
            "IL21R",
            "IL1B",
            "MSR1",
            "IL4",
            "IL21",
            "IFI16",
            "CD4",
            "BLNK",
            "ITGA2B",
            "BTLA",
            "CLEC6A",
            "CUL9",
            "CLEC5A",
            "SLAMF6",
            "GZMK",
            "CD7",
            "TNFSF15",
            "BCL10",
            "TLR4",
            "EDNRB",
            "CSF2",
            "TIRAP",
            "IL1RN",
            "KLRG1",
            "POU2F2",
            "SLAMF1",
            "STAT4",
            "CD274",
            "CD1D",
            "PDCD2",
            "CD48",
            "TOLLIP",
            "BAX",
            "AICDA",
            "IL7R",
            "KCNJ2",
            "IRF5",
            "ITLN2",
            "GP1BB",
            "ITGB1",
            "CXCL8",
            "TCF7",
            "IRF3",
            "MAPK11",
            "TNFRSF17",
            "CTSC",
            "IRAK1",
            "TNFSF13B",
            "CLU",
            "CCR1",
            "RAG1",
            "CCL4",
            "CCR6",
            "CASP10",
            "CXCL1",
            "IL3",
            "CCL16",
            "IRF4",
            "TGFBI",
            "TNFSF8",
            "IFI35",
            "IL2RA",
            "UBE2L3",
            "CCR2",
            "MME",
            "ITGA4",
            "CD70",
            "CASP8",
            "HLA-DMB",
            "IL26",
            "PDCD1LG2",
            "TRAF1",
            "TAPBP",
            "ENTPD1",
            "CX3CR1",
            "IRAK4",
            "TNFRSF10C",
            "PRKCD",
            "CDKN1A",
            "CCL26",
            "PAX5",
            "CD58",
            "HAVCR2",
            "MIF",
            "C5",
            "KLRG2",
            "CD163",
            "PTPN2",
            "LCK",
            "NCAM1",
            "MYD88",
            "TLR1",
            "CD164",
            "TCF4",
            "CXCR6",
            "IFNA2",
            "CCR10",
            "ITGAL",
            "TAGAP",
            "CD1A",
            "IKBKE",
            "HLA-C",
            "TRAF4",
            "IFNL1",
            "B2M",
            "IL12B",
            "CCL23",
            "CEACAM6",
            "BST1",
            "ITGB2",
            "PSMB7",
            "CD99",
            "CLEC4E",
            "ICAM1",
            "CD8B",
            "IL15",
            "CXCL2",
            "MS4A1",
            "CXCL12",
            "STAT1",
            "CD96",
            "IL6ST",
            "CD8A",
            "IFNB1",
            "IL10RA",
            "CD276",
            "ICAM3",
            "TLR2",
            "STAT3",
            "ARHGDIB",
            "IFNAR1",
            "TLR9",
            "IFIH1",
            "STAT5A",
            "SYK",
            "PLA2G2E",
            "SMAD5",
            "KLRC1",
            "HLA-DPA1",
            "IL2RG",
            "CD28",
            "VCAM1",
            "PTGER4",
            "TNFSF12",
            "PDGFB",
            "PML",
            "MRC1",
            "IL6R",
            "KLRB1",
            "AHR",
            "RELB",
            "IL27",
            "CSF2RB",
            "NFATC1",
            "ITGAM",
            "C1QA",
            "IL2RB",
            "PRDM1",
            "TNFRSF9",
            "ADA",
            "C1S",
            "C7",
            "PDGFRB",
            "CEBPB",
            "CD55",
            "PLAU",
            "LILRB2",
            "IL11RA",
            "TLR5",
            "CD34",
            "CR1",
            "CD81",
            "PSMD7",
            "CD74",
            "IL5",
            "CD3D",
            "GATA3",
            "C1QBP",
            "IL17F",
            "TGFBR1",
            "HAMP",
            "NOTCH1",
            "ARG2",
            "S100A8",
            "SOCS3",
            "CCL11",
            "CCL18",
            "XCL1",
            "PLAUR",
            "KIR3DL1",
            "RTRAF",
            "CD40",
            "NFKBIZ",
            "LAIR1",
            "CSF1",
            "TLR8",
            "JAK3",
            "CD6",
            "IKBKB",
            "IL1RL2",
            "THY1",
            "IL18",
            "GBP5",
            "IL20",
            "C6",
            "CASP2",
            "TNFRSF11A",
            "BID",
            "FCGR2A",
            "MAF",
            "FCGRT",
            "ICOS",
            "KLRF1",
            "CLEC7A",
            "KIT",
            "TRAF6",
            "PRF1",
            "CD83",
            "TNFRSF1B",
            "IRAK3",
            "IFNL2",
            "LITAF",
            "CASP3",
            "CD2",
            "ARG1",
            "GPI",
            "CCL7",
            "C9",
            "NCF4",
            "SERPING1",
            "CCR5",
            "NOD1",
            "ELP1",
            "LTA",
            "BCL6",
            "HLA-A",
            "XCR1",
            "CX3CL1",
            "TBK1",
            "TGFBR2",
            "IL12A",
            "TNFSF4",
            "LAMP3",
            "ITGA6",
            "LILRA1",
            "MR1",
            "TYK2",
            "GBP1",
            "HLA-DOB",
            "HLA-DPB1",
            "LAG3",
            "TFRC",
            "CMKLR1",
            "IL9",
            "LILRA6",
            "HLA-B",
            "KIR3DL3",
            "LILRB1",
            "IKZF3",
            "IKZF2",
            "IFNGR1",
            "ATM",
            "LGALS3",
            "CSF3R",
            "CYBB",
            "IL23R",
            "NOS2",
            "STAT6",
            "NFKB2",
            "IFIT2",
            "TNFRSF13B",
            "LY96",
            "TNFRSF8",
            "CD5",
            "PLAAT4",
            "IDO1",
            "ICOSLG",
            "SOCS1",
            "CD79A",
            "TAP2",
            "CXCL13",
            "ITGAE",
            "RAF1",
            "PTPN6",
            "IL18RAP",
            "MAPK1",
            "DUSP4",
            "IRF8",
            "CD24",
            "TIGIT",
            "LTF",
            "TNF",
            "PSMB9",
            "CD244",
            "CD82",
            "ICAM5",
            "IL18R1",
            "CD247",
            "HLA-DRB1",
            "CEACAM8",
            "TRAF3",
            "CHUK",
            "IRF1",
            "IL13",
            "RUNX1",
            "MASP1",
            "CFP",
            "NCR1",
            "PTK2",
            "PIGR",
            "LEF1",
            "TNFRSF14",
            "JAK1",
            "MBL2",
            "ILF3",
            "ABCB1",
            "ZEB1",
            "CD27",
            "XBP1",
            "GZMB",
            "CDH5",
            "CXCL10",
            "LTBR",
            "SLAMF7",
            "RORC",
            "HLA-DMA",
            "CASP1",
            "CEACAM1",
            "LILRA2",
            "HLA-DQB1",
            "C2",
            "CTSG",
            "TAL1",
            "PPARG",
            "IFNG",
            "MASP2",
            "HLA-DRA",
            "TNFSF10",
            "PTPN22",
            "LILRA5",
            "KLRC2",
            "CLEC4A",
            "LILRB3",
            "NFATC3",
            "CTSS",
            "ICAM4",
            "TICAM1",
            "CD44",
            "CXCR4",
            "IL19",
            "DPP4",
            "TRAF2",
            "NFIL3",
            "FCER1G",
            "IL1A",
            "ITGAX",
            "STAT5B",
            "KLRK1",
            "KIR3DL2",
            "LILRA3",
            "TNFAIP3",
            "CSF1R",
            "TAP1",
            "IL12RB1",
            "VTN",
            "PLA2G2A",
            "MCL1",
            "IL17B",
            "MARCO",
            "GNLY",
            "SH2D1A",
            "KLRC4",
            "CISH",
            "ETS1",
            "GFI1",
            "IL22RA2",
            "NFKB1",
            "IKBKG",
            "PPBP",
            "IFITM1",
            "SRC",
            "CD3E",
            "ICAM2",
            "MAP4K1",
            "IL1R2",
            "LILRA4",
            "GPR183",
            "IL2",
            "CD209",
            "CXCR1",
            "TNFAIP6",
            "KLRD1",
            "TNFRSF4",
            "CCL24",
            "LILRB4",
            "CD22",
            "GZMA",
            "S100A9",
            "TBX21",
            "SIGIRR",
            "RELA",
            "STAT2",
            "PSMB8",
            "TRAF5",
            "PYCARD",
            "C8B",
            "IFNAR2",
            "ZAP70",
            "IL1RL1",
            "NFKBIA",
            "TLR7",
            "C8G",
            "CAMP",
            "STING1",
            "PSMB10",
            "SELL",
            "C8A",
            "SMAD3",
            "PECAM1",
            "CCR7",
            "JAK2",
            "EOMES",
            "IL23A",
            "CXCL9",
            "KLRF2",
            "ITLN1",
            "SKI",
            "TGFB1",
            "MAP4K2",
            "TNFRSF13C"
        ],
        "Coefficient": [
            0.11780342830049241,
            -0.0861095572258563,
            0.07768908644587427,
            0.07501879998719942,
            -0.07441253761299314,
            0.07310217963817947,
            -0.07230501819848531,
            0.07174938632875263,
            0.07155764513458247,
            0.07109494784835015,
            -0.06611890101853671,
            -0.06527847827804997,
            0.06514383485922284,
            0.0650393813888828,
            0.06347360855105066,
            -0.06261057663838407,
            0.061698122392514716,
            0.0616078865291913,
            -0.06120471665755433,
            -0.06072899988758262,
            -0.05936963445210789,
            -0.05875457803790658,
            0.057045397063005446,
            -0.05641753745964818,
            0.05600530290529516,
            0.055030875561885864,
            0.05494813935818194,
            0.05484788653575794,
            -0.05462953245805752,
            0.053725367108684495,
            0.0534883317225078,
            -0.05322744146303811,
            -0.053194250707603585,
            -0.0530554419409965,
            -0.051174494804149616,
            0.05044058108865428,
            0.05017629188153821,
            0.0499560295015195,
            0.049709702795103464,
            -0.04963609694668196,
            -0.048185759005485176,
            -0.04814823114882016,
            0.04780259730674014,
            0.04736270294264765,
            0.04690444077499432,
            -0.04679406491655087,
            -0.04675513798301217,
            -0.0465744999083144,
            0.04654582073352469,
            0.04622760124642344,
            -0.04578211696087243,
            0.04555875451227345,
            0.04540989370654655,
            0.045029270885803364,
            0.044836209599455036,
            0.044459070866274916,
            -0.04408244132384832,
            -0.043869003706077075,
            -0.04379411050021056,
            0.043141076967394935,
            -0.042587375902711354,
            0.04232841703678221,
            0.04231923043021128,
            -0.04223428764277863,
            -0.04137382237367359,
            -0.041185593433015116,
            -0.04084414744164785,
            0.040609251826272,
            -0.04059084779339379,
            0.03878150011078762,
            -0.03867662320865693,
            0.03850892308763286,
            -0.0384444073648375,
            -0.03826009628571878,
            0.03789479302649197,
            0.037847294322480386,
            0.03782730759729394,
            0.03766677844593251,
            0.037521054557150574,
            0.03746292934520297,
            0.03731540350080519,
            0.037233042945486745,
            0.037200968524079434,
            0.037073603446494324,
            -0.03702325526858832,
            0.037020009399544404,
            0.037017407920778504,
            -0.036727303029523914,
            -0.036585887756997566,
            -0.03608285536649553,
            -0.03601982619502681,
            -0.03601555587153987,
            -0.03600851986862994,
            0.035685339411296056,
            0.03564179960858584,
            0.03521473618381314,
            -0.035213185715808865,
            0.03500000112778297,
            0.03487063149410346,
            0.034859291147435995,
            0.034857907175747105,
            -0.034816819175439585,
            -0.0345408318253315,
            0.0342455899646414,
            0.03402050634983371,
            0.033651412900733375,
            -0.03356789177894761,
            -0.03343510385063712,
            0.03274432035926174,
            -0.032663729768030905,
            -0.03231620454148628,
            0.03193747954438513,
            0.03193540609304133,
            0.0318386334292099,
            0.03178294771428164,
            -0.03175573750097043,
            -0.03174065297040875,
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            -0.031277545603166736,
            0.031010863584597672,
            -0.030945814757962684,
            0.03071092777404142,
            -0.03070741122718141,
            -0.030419274753882564,
            0.030283221560464403,
            0.03015988737488754,
            0.02990523913575303,
            0.029503829884979713,
            0.02943374857858914,
            -0.02921416163308175,
            -0.029084329879605627,
            0.029080913817908748,
            -0.028948908054578733,
            -0.028780735046417222,
            0.028600001307895733,
            -0.02844919754979249,
            0.028438016073899407,
            -0.028358032565424723,
            0.02829296669587232,
            0.028156987565211688,
            -0.028085040267392242,
            -0.028007475453285028,
            0.027989887357409548,
            -0.027941049289835276,
            0.027770939790708982,
            -0.02760707430958166,
            -0.027560768795408447,
            0.027449217897293342,
            -0.027173384796724293,
            -0.027018753568065105,
            0.027017391851722323,
            0.026854709178166583,
            -0.026773226528387664,
            0.02649978293676823,
            -0.02645559668227698,
            -0.026441310984794086,
            0.026344459448856595,
            -0.026320078117981153,
            -0.026317212222382015,
            0.026244731071073942,
            -0.026177071048976028,
            -0.026157458037969653,
            0.026150928219293722,
            0.025950682504207716,
            -0.02594242923053111,
            -0.025839487897754147,
            -0.02571794550272518,
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            -0.025311671543461037,
            -0.02520850136509851,
            0.025168488664732265,
            0.02501529778355899,
            0.024930044552328813,
            0.02488811147902085,
            0.02479672580293627,
            0.024649957621222233,
            0.024638193283966,
            0.024565986478452484,
            -0.02439497136005514,
            -0.02425716390762471,
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            -0.024032797886903337,
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            0.023941208464834874,
            -0.023845911755767286,
            -0.023773931346534966,
            0.023708830411104262,
            0.023686611321295712,
            0.023666651023406128,
            0.023630193051338066,
            -0.023319228964255714,
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            -0.02248960476603532,
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            0.021445704401578336,
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            -0.020680975952451622,
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            -0.018143543646667887,
            0.017947578113754407,
            -0.017804000936938603,
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