{
    "significant_genes": {
        "Variable": [
            "RRS1",
            "AIPL1",
            "TSEN2",
            "GAGE2D",
            "CNGA4",
            "KLF8",
            "UGT2B4",
            "ACER1",
            "LY6G5C",
            "LCLAT1",
            "APOLD1",
            "HTN3",
            "BORCS5",
            "MMP3",
            "ASCL4",
            "PTHLH",
            "RET",
            "OR13A1",
            "SLC10A1",
            "ANAPC5",
            "MFSD6L",
            "SPMIP7",
            "CAND2",
            "OR4S2",
            "TEX12",
            "TBC1D9B",
            "ZNF235",
            "ALPI",
            "B3GNT6",
            "SERPINA13P",
            "IGF2BP2-AS1",
            "AUTS2",
            "ABCA1",
            "NXT2",
            "CCL25",
            "OTOP3",
            "MAP7D3",
            "CABP4",
            "CCN1",
            "ZNF556",
            "TBC1D28",
            "ZC3H12A",
            "NEXMIF",
            "OR13C3",
            "H2BC6",
            "UGT2B11",
            "FAM170B",
            "TSKS",
            "ZNF596",
            "TTTY8",
            "CD300LD",
            "TMOD4",
            "CSAG3",
            "SERPINA11",
            "LINC00597",
            "DSCR8",
            "NXF2B",
            "OR51Q1",
            "C3orf22",
            "OR2A2",
            "IP6K2",
            "ZNF7",
            "KRTAP8-1",
            "MYH16",
            "BTNL3",
            "SHLD2",
            "KRTAP5-3",
            "SPATA31H1",
            "PSORS1C2",
            "C9orf57",
            "OR11H1",
            "CUZD1",
            "ITFG2",
            "ZNF2",
            "GUF1",
            "FGF16",
            "CSAG2",
            "FBXO21",
            "PDCL2",
            "PRAMEF5",
            "H2BC11",
            "ADRA1D",
            "PCDHGB5",
            "MAP4K2",
            "H2BC21",
            "ODAM",
            "CCL4",
            "KRT39",
            "ACTN3",
            "EVPLL",
            "LOC100192426",
            "GSC2",
            "IRS2",
            "CXCL1",
            "PCDHGB1",
            "MIR1-1HG",
            "FBXO47",
            "C20orf141",
            "TRIM48",
            "OR7E24",
            "SNORD89",
            "ROBO2",
            "ADAM21P1",
            "PITPNM2",
            "FAM27B",
            "FAM186B",
            "CTSL3P",
            "CLEC2A",
            "HSFY2",
            "SYT14",
            "OR8G5",
            "SETD4",
            "CYLC1",
            "POTEA",
            "NOMO2",
            "NDNF",
            "HHEX",
            "PPIAL4D",
            "PRSS21",
            "HACD1",
            "DEPDC7",
            "FRMD1",
            "TMEM202",
            "OBP2B",
            "CEACAM22P",
            "CDK16",
            "ANKRD20A11P",
            "NXNL1",
            "R3HDML",
            "RNF17",
            "XAGE2",
            "NFATC4",
            "GID4",
            "ZFHX4",
            "HOXD8",
            "SPATA31J1",
            "GUCY2GP",
            "NXF5",
            "PRAMEF2",
            "RAB9BP1",
            "REP15",
            "TXNL4B",
            "FATE1",
            "PTDSS1",
            "TMEM174",
            "SNED1",
            "HDAC8",
            "SNORA2B",
            "OPN1LW",
            "GRK1",
            "H2AJ",
            "LOC100240734",
            "PADI3",
            "REG3A",
            "PATE2",
            "CFTR",
            "POU4F1",
            "KRTAP5-7",
            "SLCO1B1",
            "LEMD1",
            "CFAP95",
            "KRT8",
            "BMPER",
            "LGALS14",
            "TREX2",
            "JUND",
            "PDE10A",
            "LHFPL7",
            "TAS2R40",
            "OR2C3",
            "KRT74",
            "TMIE",
            "OR5AP2",
            "LINC00200",
            "ANXA10",
            "RMDN1",
            "SNORD67",
            "FAM151A",
            "OR10J1",
            "SLC10A5",
            "GHRL",
            "ANXA8L1",
            "ADAD1",
            "PIP5KL1",
            "SNORA75",
            "SRD5A2",
            "C8A",
            "CXCL13",
            "OTOA",
            "ZNF296",
            "CNTD1",
            "ST8SIA2",
            "KIF20B",
            "FOXH1",
            "ZNF595",
            "NAT2",
            "AKR1C4",
            "CXCL5",
            "CAPN14",
            "SLC6A5",
            "H2BW2",
            "OR6Q1",
            "KRTAP10-10",
            "OR2L1P",
            "SIM2",
            "MAGEA8",
            "ST7-OT4",
            "SLC22A7",
            "MBD3L5",
            "LMAN1L",
            "CCDC144BP",
            "FIGLA",
            "OR1A1",
            "PCDHB3",
            "C20orf173",
            "FOXA3",
            "ZNF467",
            "IL11RA",
            "OR2AG1",
            "IFNL1",
            "RP1",
            "ZNF540",
            "P2RX6P",
            "OR10G4",
            "ARL14",
            "SOX30",
            "SAG",
            "SLCO4A1",
            "TRIM64",
            "FANCD2OS",
            "PCDHA9",
            "SCGB1C1",
            "TFPI",
            "LIPK",
            "MYF5",
            "OR5M3",
            "KRT24",
            "NLRP6",
            "PRDM14",
            "DHH",
            "TBX10",
            "MAGEB3",
            "KRTAP19-5",
            "SMCO2",
            "PPBPP2",
            "TMEM89",
            "DPPA3",
            "SNORA69",
            "GYS1",
            "NR4A1",
            "KTN1-AS1",
            "NCOR1P1",
            "RPL9",
            "ZFAND4",
            "KCNK16",
            "EGR2",
            "CT55",
            "TIPARP",
            "SNAR-F",
            "BTBD18",
            "CYSRT1",
            "OR4D1",
            "IL36B",
            "CDH19",
            "DIO3OS",
            "NBPF15",
            "OR1M1",
            "C7orf57",
            "FAM182A",
            "ZNF750",
            "APOBEC1",
            "SPANXN1",
            "OR13C5",
            "LINC00244",
            "SDC4P",
            "GYPE",
            "PCDHA11",
            "ZSCAN12P1",
            "BRF2",
            "LCE3C",
            "DGKG",
            "PRAMEF13",
            "GLTPD2",
            "TMCO5A",
            "OR6K3",
            "GPX5",
            "KRT85",
            "ZYG11A",
            "SNAR-B2",
            "ABO",
            "C20orf144",
            "IFNA5",
            "SEBOX",
            "CT45A6",
            "LYG2",
            "ATP6V0A2",
            "SYCE3",
            "CCDC83",
            "UCA1",
            "GATA3",
            "PLCZ1",
            "ZNF474",
            "SAMD7",
            "DEFB129",
            "KDSR",
            "UNC93A",
            "OR2AK2",
            "ZNG1C",
            "CHSY1",
            "SIGLECL1",
            "CDKN2A-AS1",
            "ARHGAP8",
            "GGPS1",
            "TTTY16",
            "OR56A1",
            "PXT1",
            "MMACHC",
            "FREM2",
            "MLNR",
            "LHX3",
            "DEFB136",
            "A1CF",
            "MAB21L3",
            "FOXD4L5",
            "CDRT15",
            "C4orf17",
            "KBTBD12",
            "TMEM52",
            "KRTAP13-2",
            "OTC",
            "ASAP1",
            "FGFR1OP2",
            "CSTL1",
            "SNORA6",
            "RBM12B-AS1",
            "SLFN14",
            "ISL1",
            "SNORA38B",
            "ZC2HC1B",
            "CLEC1B",
            "KLK8",
            "UTS2",
            "TSPO2",
            "ANKRD7",
            "WFDC12",
            "AGXT2",
            "CNBD1",
            "TP53INP2",
            "LOC392196",
            "MLN",
            "ESRG",
            "DDX53",
            "TRIM60",
            "MIOX",
            "PCSK9",
            "IGFL3",
            "PCDHGA9",
            "NTSR1",
            "HSP90AB4P",
            "TRPC4",
            "OR6C1",
            "SCARNA8",
            "PCDHB2",
            "GTF2H2B",
            "PDZK1P1",
            "USP17L2",
            "ST7-AS1",
            "CYP26A1",
            "KCNQ4",
            "NEUROD4",
            "OR5AC2",
            "PAX8",
            "OR10R2",
            "SNORD115-7",
            "BMP15",
            "KYAT3",
            "GPR15",
            "BAG2",
            "SMN2",
            "MET",
            "TUBA3D",
            "PSG2",
            "OR52A4P",
            "NOS2",
            "RBM44",
            "H4C7",
            "CYP2B6",
            "ABCA6",
            "OR3A3",
            "BDH1",
            "PRR27",
            "OR4X1",
            "ABCA13",
            "IQCN",
            "SNORA41",
            "C11orf42",
            "TTTY7",
            "KRT37",
            "PRB1",
            "OR10G3",
            "PLD6",
            "MBL2",
            "NOX5",
            "FRMD6",
            "LIM2",
            "KRT4",
            "OR7E91P",
            "WT1",
            "DEFB110",
            "SNORA1",
            "KRT26",
            "B3GNT9",
            "KRTAP6-3",
            "SPATA7",
            "CLRN3",
            "UMOD",
            "NLRP10",
            "MAJIN",
            "XXYLT1",
            "EFCAB3",
            "PTGER3",
            "KRT77",
            "TRIM40",
            "ZDHHC3",
            "IL17REL",
            "CGAS",
            "PMCHL2",
            "IFNA17",
            "PTX4",
            "RFPL1",
            "TMEM65",
            "MOS",
            "FLJ42393",
            "LCE2D",
            "ADAMTS16",
            "OR1C1",
            "PRR23C",
            "ANKRD40CL",
            "OR10G9",
            "AS3MT",
            "ZNF747",
            "CXADRP2",
            "OR9G4",
            "MTRES1",
            "OR1L8",
            "CRP",
            "ANP32D",
            "DEFB105A",
            "ZNF804B",
            "FCMR",
            "OR11L1",
            "OR11H12",
            "POM121L4P",
            "IGFL4",
            "FGF19",
            "MRGPRD",
            "TMEM95",
            "PDZRN3",
            "OR2L2",
            "PSG8",
            "TRAF2",
            "PRG3",
            "PZP",
            "VCX2",
            "OR5M10",
            "POU4F2",
            "KRT17",
            "OR6A2",
            "SPMIP10",
            "MAGED4B",
            "XKR6",
            "OR6T1",
            "CRISP1",
            "CYP11A1",
            "OR2T6",
            "TNIP3",
            "ZNF594",
            "DUSP16",
            "ZNF630",
            "EIF5",
            "NOD2",
            "CTRB1",
            "C16orf90",
            "TNP2",
            "OR6W1P",
            "ORM1",
            "HAND1",
            "AGBL1",
            "TRIM42",
            "DPYS",
            "TRPV5",
            "PCDHB6",
            "SNORA13",
            "OR13F1",
            "CALML6",
            "KRTAP13-3",
            "CLBA1",
            "GGT6",
            "ZBTB7C",
            "OR11A1",
            "ASB17",
            "FOLR3",
            "OR7C1",
            "TEKT4",
            "TBX22",
            "GNAO1-AS1",
            "LINC01558",
            "IDO2",
            "COLEC10",
            "NUDCD2",
            "OTOP1",
            "SPESP1",
            "CSRNP1",
            "OBP2A",
            "ASAP1-IT1",
            "NAPSB",
            "PAPPA2",
            "PRKAB1",
            "AANAT",
            "LDLRAD1",
            "SPRR4",
            "BPIFB1",
            "EXT1",
            "KHDC1L",
            "CCL15",
            "DEFB125",
            "CYP4F30P",
            "CWH43",
            "CCR9",
            "FOXD4L3",
            "SPMIP2",
            "H3C13",
            "GSTM1",
            "HMX2",
            "MANSC1",
            "OR1J1",
            "CSN1S2AP",
            "HS6ST2",
            "OR2T1",
            "WDR41",
            "TPI1P3",
            "PCDHGB6",
            "SLIRP-OT1",
            "DACH1",
            "FAM24B",
            "SNORA65",
            "OR4E2",
            "ZNF676",
            "RAD21L1",
            "ODF1",
            "SERPINA12",
            "ZFP92",
            "INTS1",
            "WFDC8",
            "MS4A5",
            "OR6K6",
            "CD1B",
            "FILIP1",
            "DPPA5",
            "SPDYE5",
            "PKP3",
            "SPACA5",
            "XAGE3",
            "PER3P1",
            "F13B",
            "ANXA2P3",
            "SNORA5B",
            "OR11G2",
            "GOLGA8F",
            "C3P1",
            "SERPINB13",
            "HSPA5",
            "ADM2",
            "RFPL3",
            "KRTAP6-2",
            "NODAL",
            "OPRPN",
            "LUZP4",
            "PHGR1",
            "TAAR9",
            "TMTC1",
            "KRTAP4-1",
            "OR5C1",
            "HSD17B4",
            "PRAP1",
            "NBR2",
            "FAM106A",
            "RAB21",
            "ACTC1"
        ],
        "Coefficient": [
            -1.3890312327995507,
            0.8625591864708247,
            -0.784489012344315,
            0.7334032948991026,
            0.6727488737634489,
            0.6600975329023506,
            -0.6484666907008192,
            0.6420341142924805,
            -0.6398327005419855,
            0.615728816598132,
            -0.5978976763818057,
            0.5924922833326876,
            -0.5871110952604551,
            0.5850254760432005,
            0.5449975306653889,
            -0.5357893910513521,
            0.5353667488256251,
            0.5142884106394425,
            -0.514141584606934,
            -0.510269019939186,
            0.5073395112506675,
            -0.48180732015333694,
            -0.4790293595629792,
            0.4712465453055464,
            -0.47065929784098304,
            0.4600859613513113,
            0.45307700616403196,
            0.44700911091272627,
            -0.44495076423013263,
            -0.4443896151401402,
            -0.433672481162485,
            -0.43362291359948973,
            -0.4315425128046259,
            0.420899987396016,
            0.4122817203350728,
            0.4107935259491692,
            -0.4071813885998531,
            0.40547139523040315,
            -0.4045812894342099,
            0.40454473723132417,
            0.39045400878521114,
            -0.38810491808115044,
            0.3826358359394454,
            -0.3820096144514896,
            -0.379979200900188,
            0.37437007753476703,
            0.3659846022696589,
            0.3618149645702965,
            -0.3608017629797735,
            0.3591918478319002,
            0.35659277639117765,
            0.3556143095610649,
            0.3554637193209769,
            0.3539970801820123,
            -0.3533992496737144,
            -0.3505630144883425,
            0.34885068773798356,
            0.3480648512928872,
            0.3468257810855644,
            -0.3461017250495632,
            -0.3452439485880399,
            -0.34268049141369833,
            0.3400096399419336,
            0.33990008279076467,
            0.3391344426610472,
            0.33807892852487087,
            -0.33789668846070015,
            -0.33688745547478294,
            0.33611967405277343,
            -0.33555061064648045,
            0.33397275757872064,
            0.33157013284294884,
            -0.3313640131022884,
            0.32681538935364285,
            0.3265897449056604,
            -0.3257825757199167,
            0.32537622159537116,
            -0.31906582949797774,
            -0.3169888870523469,
            -0.31673062696145304,
            -0.31457739366080284,
            -0.3129266383584313,
            -0.3108432668287374,
            0.30753963021086744,
            -0.30172744076390057,
            -0.29794502383340465,
            -0.29715010181814533,
            0.2919021494750994,
            -0.28494412577189143,
            0.2839169389196451,
            0.28146719207025855,
            0.2746786514896774,
            -0.27244985020836554,
            -0.27233030620092746,
            -0.27123909571174026,
            -0.27105619962739047,
            0.2687296559254851,
            -0.26623645549665387,
            -0.2614789193986531,
            0.2608423994694608,
            -0.25998049196084067,
            -0.2553002020354832,
            -0.2537395485997422,
            -0.2537174925158299,
            0.2528538648608397,
            -0.2524830120931101,
            0.25246648356975265,
            0.2523441915831319,
            0.24918128080846907,
            -0.24888689018274326,
            -0.24772628242668662,
            0.24635120519136253,
            0.24296406568501208,
            0.2429456543082573,
            -0.24280799689851318,
            -0.24233573760140065,
            0.2423098651020129,
            -0.24228107462746273,
            -0.2420533404632177,
            -0.2417463918277116,
            0.24106943038181508,
            -0.24024479147028235,
            -0.23995056022917938,
            -0.2397012072361854,
            0.23793170734509753,
            0.23723596148184944,
            0.2326362392644643,
            -0.23242570326623113,
            0.22598201066232806,
            0.22537377532802186,
            -0.22531035942172165,
            -0.22259075249688173,
            0.22150515273516905,
            -0.2214392713694293,
            -0.22118490373206787,
            0.2205336675986588,
            -0.22053240927321166,
            0.21989237585953517,
            0.2198363839027201,
            -0.2196303790445339,
            -0.21812543912840737,
            -0.21704146264182475,
            -0.21671997505098806,
            -0.21669493588403138,
            -0.21559052825077593,
            -0.21491227806802074,
            0.21331585784501128,
            0.21318074784923802,
            0.21244248203143568,
            0.21134333751496387,
            0.21122086786723532,
            -0.21118550762883587,
            0.20997441776137746,
            -0.2081113303447468,
            -0.2055476919610754,
            -0.2052508561959113,
            -0.20442595586188728,
            -0.20424880192777425,
            0.20292459106155336,
            0.2019963703175992,
            -0.20172503342555395,
            0.19888391762624663,
            -0.1977763920892955,
            -0.1969914386358978,
            0.19636626973919674,
            -0.19620962045036672,
            -0.19395094523256462,
            -0.19344788383092676,
            0.1929941016835464,
            0.19284577075435283,
            0.19054386065143916,
            -0.1904633224759591,
            -0.18734044313632095,
            0.18629499571464056,
            -0.1838843509731923,
            0.18339522321343302,
            0.18117451388816116,
            0.17804005444342244,
            0.17724910980848912,
            -0.17718451783628975,
            -0.17706212498011958,
            0.17694739701501963,
            -0.17599360559535737,
            0.17529620709882768,
            -0.1745511316333246,
            0.1743776994470092,
            0.1730137216917561,
            0.17250013179481322,
            -0.17218133437327054,
            0.16972422990944477,
            0.16958392974841419,
            -0.1694703608647743,
            0.16930004384015124,
            -0.16874471113798395,
            0.16751122330787116,
            0.1672479145237806,
            -0.1657864999469006,
            -0.16530833845034767,
            -0.16530803535063746,
            0.16485033463595686,
            -0.1646844911291478,
            -0.164671845311714,
            -0.16461512981548487,
            -0.16460462821868008,
            -0.16286044270911243,
            -0.1609752748594205,
            0.16081893279095266,
            0.1602550965844588,
            -0.16013509157745898,
            -0.15902442099163744,
            0.15781542542681487,
            -0.1569701936325854,
            0.1555262572585177,
            -0.15390476392919433,
            -0.15170574348745383,
            0.15138890731698032,
            0.15117225219216213,
            0.1504644396659258,
            0.15025376142523006,
            0.15015344100583553,
            -0.14998891815082324,
            -0.14973296205415873,
            -0.14950435238933182,
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