{
    "significant_genes": {
        "Variable": [
            "OGFRL1",
            "GCM1",
            "NDOR1",
            "BTBD7",
            "CAPRIN2",
            "TBX2",
            "GRIK4",
            "MSX2",
            "PTPRT",
            "CSN3",
            "HNMT",
            "BCAS3",
            "ADH6",
            "NUDT9",
            "ACTN3",
            "SPINK4",
            "H4C5",
            "DELEC1",
            "SLC22A3",
            "ALOX12B",
            "PRPSAP2",
            "S100A4",
            "SLC6A20",
            "RHOBTB1",
            "SFTPB",
            "LIMA1",
            "RTN3",
            "H1-5",
            "COL4A6",
            "STON1-GTF2A1L",
            "HMGB3",
            "NRP2",
            "SLC66A3",
            "EFHD1",
            "H2BC3",
            "ST3GAL5",
            "OTC",
            "SNTG1",
            "IQSEC3",
            "XCL1",
            "RTN2",
            "NME5",
            "ACAD8",
            "C1QTNF3",
            "TAS2R8",
            "C4A",
            "KCNJ13",
            "KRT20",
            "SNTB1",
            "PNPLA2",
            "USP36",
            "PRKD1",
            "SERPINB5",
            "RNF24",
            "FBLN1",
            "MYLIP",
            "P2RX3",
            "FBLN2",
            "ACOT8",
            "PSMC1",
            "IGHG3",
            "SERPINE1",
            "SST",
            "GJC2",
            "LRRC75B",
            "RNASE4",
            "HCFC1R1",
            "SNIP1",
            "SPINK5",
            "AVPR1B",
            "CDY1",
            "FLJ20712",
            "TMEM92",
            "APBB2",
            "ABHD4",
            "FXYD7",
            "GUCY1B2",
            "SOWAHC",
            "ASIC4",
            "RBP1",
            "HIGD1B",
            "WBSCR23",
            "FCAR",
            "DEFA4",
            "TDRD12",
            "COX7A2",
            "TSSK1B",
            "REG1B",
            "RNF8",
            "TP53I11",
            "SSTR3",
            "ZP2",
            "CHST1",
            "PCDHB6",
            "DNAH7",
            "PLIN1",
            "GJA3",
            "ADGRG3",
            "F8A1",
            "MANF",
            "TUBAL3",
            "MMP10",
            "PPBPP2",
            "IGF2-AS",
            "CD28",
            "SSTR5",
            "HILPDA",
            "BMP4",
            "BTNL3",
            "PLIN2",
            "TRAF3IP1",
            "OPRD1",
            "MASP2",
            "SPN",
            "SERTAD2",
            "ROR2",
            "IL12A",
            "GREM1",
            "ALDH1L1",
            "ENOSF1",
            "OMP",
            "VCX",
            "CNNM4",
            "CSRP3",
            "DRD5",
            "DNAH17",
            "INCENP",
            "TPM3",
            "BABAM2",
            "CLDN1",
            "CLCA4",
            "CDC14A",
            "NNT",
            "EVX1",
            "DIRAS3",
            "TLE6",
            "TLR2",
            "KLF15",
            "POLR1B",
            "CNR2",
            "SVIL",
            "IL36G",
            "OR2C1",
            "DSCR4",
            "SULF1",
            "CHI3L2",
            "COCH",
            "CETN1",
            "DIAPH3",
            "ITGA6",
            "VPS53",
            "CXCR3",
            "RIOX1",
            "PNMA3",
            "CSN2",
            "OSGIN1",
            "CFAP68",
            "PXDC1",
            "SPTSSA",
            "ATP2B1",
            "DEAF1",
            "CDC25B",
            "P3H4",
            "MCOLN1",
            "MLN",
            "ETS1",
            "SPPL2B",
            "ZFP36L2",
            "ADAM5",
            "GPR162",
            "ZBTB7C",
            "CCIN",
            "COL7A1",
            "CEL",
            "MDM1",
            "RFPL3",
            "ADAM11",
            "PIGV",
            "CNTF",
            "KIAA0408",
            "CDC14B",
            "CYLC2",
            "POGLUT2",
            "OXSR1",
            "PROZ",
            "SLC43A3",
            "F9",
            "PPP1R3A",
            "FMO3",
            "TDRKH",
            "RNLS",
            "BEAN1",
            "INTS11",
            "DNAAF8",
            "MXRA5",
            "CLC",
            "TREX2",
            "COPS3",
            "AQP6",
            "FLT1",
            "S100A5",
            "GUCA2B",
            "ENO3",
            "CYP2C8",
            "ABCB4",
            "CLASP1",
            "ANK1",
            "IFI6",
            "ETV2",
            "GABRA4",
            "HTR3A",
            "COX6A2",
            "THSD7A",
            "TTTY9A",
            "MC2R",
            "OMG",
            "ALOX5",
            "ST3GAL4",
            "CRNN",
            "GARNL3",
            "APCS",
            "CALML3",
            "NEUROD4",
            "NFATC4",
            "LMO1",
            "SLC27A3",
            "PGR",
            "KRT81",
            "HHIPL2",
            "CEMIP",
            "OLIG2",
            "ABCA6",
            "LTB4R2",
            "KCNA10",
            "CLSPN",
            "ELAVL3",
            "FHL5",
            "HSPG2",
            "DHX35",
            "TGFBR3",
            "CADM1",
            "ROS1",
            "USPL1",
            "ADCY8",
            "COL9A3",
            "UGDH",
            "FOXN3-AS2",
            "DEPTOR",
            "TMEM70",
            "ACTL8",
            "CPNE6",
            "NTRK1",
            "TACR1",
            "IDO1",
            "SMPD3",
            "TGM4",
            "SIX5",
            "IRS4",
            "OR3A2",
            "WDR33",
            "APOBEC2",
            "IGFBP4",
            "LRRC49",
            "OR7E156P",
            "WFS1",
            "MYOD1",
            "CDH22",
            "PNLIPRP2",
            "KRT85",
            "MPZ",
            "MSMO1",
            "OR7C2",
            "TMEM245",
            "TMEM248",
            "LPAR4",
            "ZNF205",
            "KCNE1",
            "CLCN1",
            "BRSK2",
            "HHCM",
            "SMO",
            "CFHR1",
            "OTOF",
            "RBM12B-AS1",
            "DEPDC5",
            "C1QA",
            "H1-4",
            "ENO2",
            "CNGB3",
            "PRKCQ",
            "RDH8",
            "MOGAT2",
            "CTRB1",
            "OCM",
            "CRCT1",
            "ASAP2",
            "ZNF415",
            "IFNA21",
            "OR7A17",
            "LBH",
            "ZIC4",
            "RAB29",
            "HAP1",
            "AOPEP",
            "COL4A2",
            "POU3F1",
            "ITGB1BP2",
            "MLEC",
            "C5AR2",
            "ZBTB20",
            "OR2H2",
            "MRPL41",
            "POLR1D",
            "ZNF154",
            "NKX6-1",
            "TTPA",
            "ZPBP",
            "NHLH2",
            "KNTC1",
            "CDKL5",
            "SIGLEC1",
            "GSTA3",
            "MEGF6",
            "PSCA",
            "IFNGR2",
            "MAFK",
            "KCNQ4",
            "SCARF1",
            "SLC16A10",
            "GFRA3",
            "TNIK",
            "EPHX3",
            "CHAT",
            "ACSL1",
            "NPAP1",
            "PRSS3P2",
            "TAS2R9",
            "RHOBTB2",
            "H2BC17",
            "MS4A2",
            "DDX10",
            "ZNF556",
            "BFSP1",
            "LDLRAD4",
            "HAS1",
            "OR51E2",
            "ACOXL",
            "MGAM",
            "SLC25A42",
            "PSMB5",
            "RNF126P1",
            "TPSB2",
            "BMP10",
            "GC",
            "C1QB",
            "DNALI1",
            "SLC27A6",
            "CCL11",
            "CRISPLD2",
            "ZNF646",
            "IFI44",
            "CCNA1",
            "CELA2B",
            "PSIP1",
            "RORB",
            "SLC7A5",
            "SLC35A1",
            "PRND",
            "SOD3",
            "NPL",
            "DDX51",
            "SLC34A1",
            "NPY6R",
            "XRCC4",
            "KCNJ15",
            "SAGE1",
            "PLA2G5",
            "BRINP2",
            "BMP3",
            "CHODL",
            "HNF4G",
            "ARL17A",
            "SYNPO",
            "KEL",
            "CASP8",
            "BCAT1",
            "SH3BGR",
            "SLC22A6",
            "GJB1",
            "HPSE",
            "GCH1",
            "HCRTR2",
            "FCGR2C",
            "LARP6",
            "AGBL2",
            "GHRH",
            "DCBLD2",
            "LRRN3",
            "DNM3",
            "ECH1",
            "GCNT3",
            "GPD1",
            "ZNF197",
            "SFRP5",
            "RALGPS2",
            "DDHD2",
            "SLC35F5",
            "ADCYAP1R1",
            "VRTN",
            "TMEM47",
            "IGFBP2",
            "CABP1",
            "CBL",
            "PLAAT4",
            "SPON2",
            "PDE3B",
            "ELN",
            "KRT76",
            "FER",
            "ALDOC",
            "H3C8",
            "CNTN1",
            "TG",
            "SAA4",
            "MRAS",
            "PRKAR1B",
            "NOTCH4",
            "PPFIA4",
            "ABCA7",
            "FCN2",
            "OR2S2",
            "CCL27",
            "PLEKHF1",
            "CASS4",
            "CHIA",
            "KLK12",
            "PAEP",
            "GDNF",
            "SEMA4C",
            "CUBN",
            "DNAH2",
            "AP1G1",
            "PGAP3",
            "GGA2",
            "DKKL1",
            "NAV1",
            "DSCAM",
            "SCN2A",
            "BPIFA1",
            "ARHGAP5",
            "ADTRP",
            "PNLIPRP1",
            "FST",
            "CALY",
            "MIP",
            "HOXC10",
            "PRM1",
            "SIX6",
            "ASTE1",
            "GABRB2",
            "PRKCH",
            "SMAD5-AS1",
            "TP73",
            "BICDL1",
            "ZDHHC14",
            "MAN1C1",
            "ERBB4",
            "CHD2",
            "GMCL1",
            "ZXDA",
            "FAM107A",
            "CCL7",
            "CRYBA2",
            "SLC22A2",
            "PTCRA",
            "ZFY",
            "TMEM242",
            "HMGA2",
            "DGKI",
            "SMURF2",
            "GALC",
            "CYP4A11",
            "ONECUT2",
            "KLK14",
            "ADAM8",
            "CDR1",
            "DPYSL4",
            "VPS13D",
            "OGN",
            "FAAP100",
            "SCNN1D",
            "RFPL1",
            "CATR1",
            "SSH1",
            "VIPR1",
            "KRT33B",
            "FAM30A",
            "STARD8",
            "CD1B",
            "SLC22A11",
            "SCGB2A1",
            "MCF2",
            "H4C7",
            "GAPDHS",
            "H3C1",
            "DMC1",
            "PLXNB3",
            "PGLYRP1",
            "CCL18",
            "IL32",
            "CXCL5",
            "UCN",
            "TENM2",
            "APLNR",
            "HESX1",
            "RNASE1",
            "P3H3",
            "CCL5",
            "FUT5",
            "BCAN",
            "TCAP",
            "PPP1R12B",
            "ASPA",
            "ACBD3",
            "LIFR",
            "TKTL1",
            "ITGA3",
            "AHNAK2",
            "GPR12",
            "SLC25A12",
            "MTUS2",
            "HP",
            "ADRA2C",
            "DGCR6L",
            "C22orf31",
            "CLDN16",
            "GPR37L1",
            "MC3R",
            "ETFB",
            "KIF5A",
            "LMAN1L",
            "TMPRSS11E",
            "ST8SIA2",
            "P2RY14",
            "KCNIP2",
            "PDLIM7",
            "RASA3",
            "CYP2B7P",
            "ME2",
            "GIPR",
            "ACLY",
            "IGHV4-31",
            "PRAMEF12",
            "ISG20",
            "PSORS1C1",
            "TMEM255A",
            "IER3IP1",
            "SUGP1",
            "DPP4",
            "ACR",
            "NGB",
            "ARHGDIG",
            "AMBN",
            "LUZP4",
            "CALCOCO1",
            "RLN2",
            "MAGEA9",
            "IGSF9B",
            "GPR4",
            "SNAPC5",
            "EPS15P1",
            "TBX6",
            "SPICE1",
            "FOXD2",
            "ACTN2",
            "KLRA1P",
            "BDKRB2",
            "MYOZ1",
            "OR7A5",
            "C8orf17",
            "KCTD14",
            "IL1RL1",
            "LINC00474",
            "GUCA2A",
            "GRAMD2B",
            "UTRN",
            "CCDC33",
            "CRP",
            "TAS2R1",
            "CCL20",
            "SEMA7A",
            "FMNL2",
            "FAM83E",
            "GBX2",
            "PLAAT2",
            "LIMS2",
            "PAGE4",
            "NR1H4",
            "SLC28A2",
            "EMP1",
            "H3C3",
            "MAST2",
            "LPAR6",
            "PPM1D",
            "DGCR6",
            "RGCC",
            "RRAGB",
            "SOCS7",
            "ADPRH",
            "HAPLN2",
            "TACR3",
            "BST1",
            "ATXN3L",
            "ARL14",
            "ABCA11P",
            "GAS2",
            "NXF3",
            "MYH4",
            "OR7E125P",
            "CHRM2",
            "LYZL6",
            "CRYGB",
            "MYO3A",
            "PLGLB2",
            "DHODH",
            "P2RY13",
            "PIWIL2",
            "LPAL2",
            "PURG",
            "MTNAP1",
            "PAPSS2",
            "IGHG2",
            "NECTIN3",
            "GPR21",
            "MAGED1",
            "FPR3",
            "HDAC9",
            "POMC",
            "PHYHIP",
            "DGKA",
            "FAP",
            "MBD5",
            "KCNF1",
            "SEC14L4",
            "TAT",
            "GPR68",
            "TRPV5",
            "PAFAH2",
            "TNFRSF4",
            "USP2",
            "IGFBP3",
            "GOLGA6A",
            "CTNND2",
            "TAAR2",
            "HOXB8",
            "NACA2",
            "ASCL3",
            "GFAP",
            "GZMK",
            "GPR22",
            "NSMCE2",
            "MUC2",
            "NTN3",
            "P2RX6",
            "FLVCR2",
            "ALX3",
            "NOL10",
            "KIR2DS3",
            "SHOX2",
            "KRTAP5-9",
            "FOXL1",
            "TM6SF2",
            "DEFA6",
            "TCL1B",
            "MERTK",
            "ROM1",
            "KCNN1",
            "TGM3",
            "IQSEC2",
            "FLT4",
            "ELOVL1",
            "SPP1",
            "PRKG2",
            "PDGFD",
            "SFTPA2",
            "IL21",
            "EDA2R",
            "NTSR2",
            "ADRA2A",
            "LCN1",
            "RIMS3",
            "PRY",
            "PLAC4",
            "NXF2",
            "MT1H",
            "GFM1",
            "GABRR2",
            "EPHB1",
            "VPREB3",
            "JADE2",
            "SH2D1A",
            "RAB31",
            "SUGCT",
            "GH1",
            "DIRAS2",
            "PKD2L2",
            "FRAS1",
            "DNAI7",
            "NPBWR2",
            "CCR3",
            "TREM2",
            "TPSAB1",
            "IQCC",
            "F8",
            "MUC5B",
            "RPL39L",
            "PRSS21",
            "GNG13",
            "INSL4",
            "RAB11FIP3",
            "PLA2G10",
            "P2RY10",
            "MROH9",
            "CD4",
            "IL12B",
            "DUX3",
            "HHLA1",
            "ARHGEF9",
            "NMUR1",
            "SRY",
            "MEP1A",
            "LRRK1",
            "ADAM7",
            "AURKC",
            "CBR1",
            "CADPS2",
            "KRT16",
            "LINC01587",
            "SOX21",
            "FZD8",
            "ZNF322P1",
            "ARL6IP5",
            "IL19",
            "CHRNG",
            "GCSH",
            "PICK1",
            "FAM90A1",
            "CPOX",
            "RGS16",
            "POLH",
            "MTBP",
            "TP53TG3",
            "BBS1",
            "ADAMTS9",
            "ADD3",
            "NHERF2",
            "ZKSCAN7",
            "CHRNB2",
            "TNNI3K",
            "VPS37A",
            "PLA2G4C",
            "FBXO40",
            "CHRNA9",
            "JUN",
            "FNDC8",
            "KRT35",
            "LILRB5",
            "GRIN2D",
            "PRDM4",
            "EGF",
            "PPIF",
            "TSPAN7",
            "PI4KA",
            "TSPAN1",
            "SMPX",
            "TBCB",
            "COL5A3",
            "COLGALT1",
            "KCNV1",
            "FZD9",
            "OR1F2P",
            "RAI1",
            "FOLR2",
            "NRG2",
            "PLA2R1",
            "SF3B4",
            "ZNF324B",
            "FKBP10",
            "APOC1",
            "CDC42",
            "HOXA2",
            "GJA8",
            "FAT1",
            "RRAGD",
            "TP53I3",
            "UFD1",
            "ASPN",
            "IFNA10",
            "ZNF749",
            "CDKN2A",
            "BNIP3",
            "MAGEB3",
            "GRM6",
            "C4B",
            "VCX2",
            "CDY1B"
        ],
        "Coefficient": [
            0.7647809488141221,
            0.666255530885454,
            0.6457926526048089,
            0.6273079953651737,
            -0.6022922126220618,
            0.5907734365432427,
            0.5786914079781702,
            -0.5720365126891894,
            0.5624650808517146,
            0.5621863207543448,
            0.5583760908977939,
            0.5318268443935732,
            -0.5287913201704691,
            -0.5197823318845207,
            -0.5112785217945162,
            0.4963618341057183,
            0.4958923128241835,
            -0.4954605305323683,
            -0.49431611557437194,
            -0.47569199269520784,
            0.4694095206052249,
            0.4686337356385226,
            -0.46834453111249286,
            -0.46822752154358904,
            -0.459760571588892,
            0.4566587327820415,
            0.446285489382396,
            -0.4450739993508098,
            -0.43637354854784527,
            -0.4266051635780962,
            -0.4206095496530589,
            -0.41329082258056193,
            -0.41322322543716583,
            -0.41102886231732355,
            0.4104228638736953,
            0.4100616779344371,
            0.4051398261452894,
            -0.4020392155297233,
            -0.40181594640683466,
            0.39945615191120504,
            -0.39733971718081146,
            -0.3893870614989898,
            -0.38722186327173824,
            0.3871920634559863,
            -0.3844540130763919,
            0.3750935976000107,
            -0.3749705478930628,
            0.37217654196493133,
            -0.3701722095870454,
            0.3653752298895126,
            -0.3636573059627772,
            0.36003081937172976,
            0.35820227723388215,
            0.3556260998685939,
            -0.35542958544057085,
            -0.35504272791675123,
            0.3518388885691313,
            0.351060221600189,
            0.34604935125769015,
            0.34529168341183414,
            -0.3428303203670579,
            -0.341897965683546,
            0.3402038126627274,
            -0.3395831960362093,
            0.3375477494833237,
            0.33378570451691336,
            0.33316926194632396,
            -0.33210137866267186,
            0.33127677073912276,
            -0.3257360361784641,
            -0.32051588440506956,
            -0.318478592278678,
            0.3179672689747026,
            -0.31688460366684806,
            -0.3125445485056487,
            0.3037775394505512,
            -0.3023810613250343,
            0.3002431389936265,
            -0.30022370167350465,
            0.29888430911033914,
            -0.2985157162107171,
            -0.29828409081250995,
            0.29713906856464656,
            0.29554836814193364,
            -0.2948791023873982,
            0.2947628820972273,
            0.2929872233499496,
            -0.29252410220391245,
            0.29247628686519117,
            -0.29161032381211716,
            0.2915657166900156,
            -0.29154488685696855,
            -0.29037131790417103,
            -0.29021445799343465,
            -0.28833082300080887,
            0.28627453994594887,
            0.28595320617641223,
            0.28570394723631654,
            -0.2851375694681058,
            0.2848831412456524,
            0.27953351792849834,
            -0.2789305494237194,
            0.27820948132604256,
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