{
    "significant_genes": {
        "Variable": [
            "AADAC",
            "A4GALT",
            "ABCA3",
            "AAR2",
            "AAGAB",
            "ABHD17B",
            "AATK",
            "ABCD2",
            "AANAT",
            "ABHD11",
            "ABCB8",
            "ABCB6",
            "ABCC6",
            "ABCG5",
            "A1CF",
            "ABCC6P1",
            "AAMDC",
            "AAMP",
            "AAAS",
            "ABCC10",
            "ABCA8",
            "ABHD5",
            "ABCB1",
            "ABCC4",
            "ABCD1",
            "ABCB11",
            "AACS",
            "ACO1",
            "ACHE",
            "ABCA11P",
            "ACTR5",
            "ACSF2",
            "ADAM17",
            "ADAM19",
            "AATF",
            "ABLIM3",
            "ABHD10",
            "ABHD18",
            "ACBD4",
            "ABCG1",
            "ABHD6",
            "ACTN2",
            "ABCB7",
            "ACVR2A",
            "ABCC2",
            "ABCC9",
            "ACOT1",
            "ADPRM",
            "ABHD3",
            "ACOXL",
            "ACOX1",
            "ABTB2",
            "ABCF1",
            "ABCC1",
            "ACRV1",
            "ACSL1",
            "ABRAXAS2",
            "ADARB2",
            "AASS",
            "ACTR3P2",
            "ADRA1B",
            "ACAA2",
            "ABCG2",
            "ACTG1P4",
            "ACSM2A",
            "AARS1",
            "ACD",
            "ACTL7B",
            "ADGRV1",
            "ABCD1P2",
            "ACSM1",
            "ACSL4",
            "ABCC5",
            "ABCD3",
            "ACTL7A",
            "ADRA2B",
            "ACTA2",
            "ABCA7",
            "ABHD8",
            "ALDH3A1",
            "ACAD10",
            "ADRA1A",
            "ADAM22",
            "ADAMTS13",
            "ADH5",
            "ABCB9",
            "ACSBG2",
            "A4GNT",
            "ACTR3B",
            "ABCA6",
            "ADAM3A",
            "ABT1",
            "ABCA12",
            "ABHD2",
            "ADGRA3",
            "ACTC1",
            "AARSD1",
            "ADGRA2",
            "ABI3BP",
            "ADGRG1",
            "APH1B",
            "AIRE",
            "AMFR",
            "ABAT",
            "ABCA1",
            "AMACR",
            "ABO",
            "ACSL3",
            "ACR",
            "BRF1",
            "ADGRG3",
            "ALG8",
            "ALG6",
            "B3GNTL1",
            "ADIPOR2",
            "ACVR1",
            "ABHD14A",
            "ABR",
            "ADAP2",
            "ACTR2",
            "ACSS3",
            "ADAMTS20",
            "ADAM15",
            "ACADSB",
            "ACKR1",
            "ACOT13",
            "ABHD4",
            "ACVRL1",
            "ACP6",
            "ADCY6",
            "ADPGK",
            "AGRP",
            "ABCG4",
            "ADA",
            "ADH1C",
            "ANO1",
            "ACSM5",
            "AGBL5",
            "AKIRIN1",
            "AGBL3",
            "ACTA1",
            "ALG12",
            "ADTRP",
            "AGFG1",
            "ABCA5",
            "AMH",
            "AMIGO3",
            "CH25H",
            "ARNT",
            "ACTR8",
            "ACTBP9",
            "ACKR3",
            "ACSBG1",
            "CDA",
            "ABCC8",
            "ADRA1D",
            "ANGEL2",
            "ACOT2",
            "CARS2",
            "ACTR1B",
            "ADCY7",
            "ACAT1",
            "ADRA2A",
            "ACTR6",
            "APIP",
            "ADAMTS3",
            "AGTPBP1",
            "ABCE1",
            "AGAP10P",
            "ADCYAP1R1",
            "DAO",
            "ADAM5",
            "AKAP10",
            "ABITRAM",
            "ANGPT4",
            "ACADL",
            "ADAM30",
            "ACADM",
            "ACAD8",
            "GSTT1",
            "AFF1",
            "ACP2",
            "ATP13A3",
            "AFF3",
            "ALG11",
            "ADAM28",
            "ADCY1",
            "AGPAT4",
            "ACOX3",
            "ADCY2",
            "CRLF3",
            "ADD1",
            "BTF3P13",
            "CD24",
            "ATP5MC2P1",
            "ANGPTL3",
            "AMN",
            "ACTB",
            "ABL1",
            "DNAJC28",
            "DACH1",
            "ACOT11",
            "ABCB4",
            "ALDH3A2",
            "ASCL1",
            "ACAA1",
            "ABI1",
            "ADAMTS8",
            "AIDA",
            "ADAMTSL2",
            "AKAP17A",
            "ADAM9",
            "KCND1",
            "ACAP1",
            "ADAR",
            "ATP2C2",
            "BHMT2",
            "ADD3",
            "TTR",
            "ARL4D",
            "STAT5B",
            "ACOT8",
            "CA5BP1",
            "ALDH1A3",
            "ENO3",
            "ACTN4",
            "API5",
            "AKR1C3",
            "BMAL2",
            "CDH6",
            "OPN1SW",
            "AHSG",
            "ABCF3",
            "ANKRD49",
            "ADIPOQ",
            "ACTL6B",
            "ADORA3",
            "ART3",
            "ADRB1",
            "ARL3",
            "ANKRD2",
            "ARL15",
            "ARSF",
            "CLCNKA",
            "ARSA",
            "ALG13",
            "ANGPTL4",
            "CD226",
            "DARS2",
            "ADCY10",
            "APPL2",
            "BRS3",
            "ACP5",
            "APOBR",
            "ALOX15",
            "APOM",
            "ARHGAP1",
            "BDKRB2",
            "ANKRD1",
            "ATP6V1B1",
            "AKR1C1",
            "ACSL6",
            "BAHCC1",
            "ADAT1",
            "ASPHD1",
            "MYBPC2",
            "ABCF2",
            "ADGRG2",
            "C3orf36",
            "ACYP2",
            "ACADS",
            "GASK1B",
            "ARG1",
            "ARHGAP25",
            "CCPG1",
            "BCAS4",
            "ADD2",
            "APBB1IP",
            "COIL",
            "ACACB",
            "DSC1",
            "CHP2",
            "ASPN",
            "KDM4D",
            "ANKRD27",
            "AMMECR1",
            "CRYZ",
            "ASTN2",
            "GEMIN8",
            "ADAM23",
            "ADARB1",
            "ACTR3",
            "ARB2A",
            "AKR1C2",
            "ARC",
            "BACE1",
            "ADISSP",
            "MTNR1A",
            "AMIGO2",
            "LNPEP",
            "ADAMDEC1",
            "ADAM21",
            "BTRC",
            "ANXA8",
            "SP3P",
            "ANKRD12",
            "RGS9",
            "AIMP2",
            "GCFC2",
            "B4GALT4",
            "ADAMTS1",
            "HLA-DQB1",
            "ANXA13",
            "DKKL1",
            "ALOXE3",
            "ASH1L",
            "ACSL5",
            "CD82",
            "ADAMTS12",
            "ACIN1",
            "AGO3",
            "ACTG2",
            "ACAT2",
            "AGFG2",
            "BCKDHB",
            "KCNC4",
            "AGAP9",
            "EXOC6B",
            "AGAP5",
            "ANKFY1",
            "ACTMAP",
            "AGBL2",
            "COQ8B",
            "DDX60",
            "BTN3A2",
            "CLIP4",
            "ADGRL4",
            "ALX4",
            "ELANE",
            "CDH11",
            "ADAM3B",
            "AEBP1",
            "ADAMTSL3",
            "AAK1",
            "XIAP",
            "AP1G1",
            "BIN3-IT1",
            "APOBEC1",
            "ALS2CL",
            "CHRNA4",
            "ADAP1",
            "AGK",
            "DNAI7",
            "DPM1",
            "BCAT2",
            "PDZRN4",
            "ACACA",
            "LSP1",
            "AASDHPPT",
            "ZNF37BP",
            "ADAM7",
            "FZD9",
            "ADM",
            "HSPB2",
            "ASXL1",
            "ENTPD1-AS1",
            "EPN3",
            "AIMP1",
            "INAVA",
            "CRTAM",
            "OAS1",
            "DBF4B",
            "ASF1B",
            "GNLY",
            "AQP9",
            "CADM3-AS1",
            "IZUMO4",
            "ACAP2",
            "ADORA2A",
            "APCS",
            "AGR2",
            "AOAH",
            "RRP7A",
            "MANEA",
            "ARHGEF2",
            "DNAJB5",
            "GNMT",
            "ACSM2B",
            "ANXA8L1",
            "ABCC6P2"
        ],
        "Coefficient": [
            -0.17924324516006182,
            0.1466588914473001,
            0.08975638651994676,
            -0.08528829583797946,
            -0.08359180778995201,
            -0.08237388656893667,
            -0.08029507001235668,
            -0.07978759082147086,
            -0.07916650435246092,
            -0.06782499431521676,
            -0.06399817537165893,
            0.05555001480379537,
            -0.05536797565797751,
            -0.054698755077169516,
            -0.053023645600131085,
            0.04742724190511237,
            0.045516306181597875,
            0.045335874335186044,
            0.04487945670895372,
            -0.04327794464581279,
            -0.0420958828937542,
            -0.04182803388265604,
            0.04020006070305133,
            0.039810154523075424,
            -0.0391465916988627,
            0.036322742298103984,
            -0.036129398113634144,
            0.0345026710708174,
            0.03446166091391047,
            -0.03424508664657055,
            -0.034096479344269376,
            0.03369815259452044,
            -0.032908687694815815,
            -0.03216378433541824,
            0.031886529417471145,
            -0.03145377288483425,
            -0.030430369921511703,
            -0.03028758475059752,
            0.029930026312042005,
            -0.02969325077297164,
            0.029573290194357695,
            -0.02914556915059358,
            0.0287299675071892,
            0.028153408961474755,
            -0.025131769670656435,
            0.024841475904535525,
            -0.024586578515023726,
            -0.024355418361117986,
            0.02425896003995531,
            -0.02354284565128798,
            -0.02326407982951974,
            -0.023250765875490166,
            -0.022759269256591025,
            -0.02255272282403019,
            -0.02115995579877349,
            0.02045501888008188,
            -0.02020267513089393,
            0.019986873460983764,
            0.019543986486491693,
            -0.019430608439104078,
            0.019031561532661716,
            0.018510360243132892,
            -0.017878721478540912,
            -0.017751726024579684,
            -0.017569058924085387,
            0.017097677657890855,
            -0.01682897049396874,
            -0.016608601285409023,
            -0.016435165020624948,
            -0.01603419503632999,
            0.015960919037990892,
            0.015933630206521165,
            0.015626298849732073,
            0.015343928662047729,
            -0.015299424283109382,
            0.015071067165794646,
            -0.015054450070566659,
            -0.014931506182556117,
            -0.014441762278541595,
            0.014211165362445793,
            -0.014015345677758697,
            -0.0138097111118678,
            0.013758894290328285,
            -0.013696373850599273,
            -0.01359448386910848,
            0.01352566163420805,
            0.01334704325595949,
            0.01313656305904,
            0.013120099662689054,
            0.013032590986881415,
            0.012808933148173496,
            -0.012289086921659772,
            -0.011991086854446338,
            -0.011436986308550114,
            -0.011252917140902928,
            -0.011158992869039413,
            -0.011107828120053679,
            -0.011045032215713523,
            0.011001101558830297,
            0.01046239474038355,
            -0.010460582295718454,
            0.01026453952907288,
            0.01004344905031199,
            -0.009916106875881936,
            -0.009885048962489333,
            -0.009798244664768155,
            -0.009693787987980228,
            -0.009538267536373829,
            0.009505270813314084,
            0.009386557444927515,
            0.009331566045524453,
            0.009324554568913498,
            0.009014374307377754,
            -0.008735075800735917,
            0.008551414553266998,
            0.008517069134696723,
            -0.008444928399135925,
            -0.008058321715339602,
            0.008002034704460856,
            -0.007859012500968337,
            0.00783651018834742,
            -0.007814391325419683,
            0.007798279112492959,
            -0.007767949992150195,
            0.007749551929483478,
            0.0075755293283739185,
            -0.007447336702152238,
            0.007404601734128135,
            0.007343892859362868,
            0.007331375921699491,
            0.007127963954688909,
            -0.006692038258092807,
            -0.006684513666986747,
            -0.0065813641900361215,
            0.006557928531682554,
            -0.006492326027677903,
            -0.006433243002266648,
            -0.006322486089891526,
            0.0061887696698770065,
            -0.006108078791173906,
            -0.006092225022145856,
            0.0060405935248796635,
            -0.005958552691213188,
            -0.005833430726038478,
            0.005708828785890674,
            0.005638834436250888,
            0.005609079169193034,
            -0.005517907184496703,
            -0.0054940588496943665,
            -0.005282238835507937,
            -0.005084750255041427,
            -0.005006868482368134,
            -0.00496437361335161,
            0.004941876713179978,
            0.004941774645212626,
            -0.004924696362602753,
            0.004885188208221211,
            -0.004861490252198662,
            -0.004854906133353881,
            0.004817140482947748,
            -0.00467162935062319,
            -0.004563488079692619,
            -0.004518017017172285,
            0.00446618877697758,
            0.004407013302593109,
            -0.004381547547935548,
            0.0043204468538257795,
            -0.004264944163534678,
            -0.0041523088150542745,
            -0.0040718056832470765,
            0.004058944212318084,
            -0.004000691462113001,
            0.003965465364608628,
            0.0039372090989737004,
            -0.003863866406966998,
            0.0038162939846480815,
            -0.00364793936764043,
            0.0036304270430141793,
            0.0035932079106064403,
            0.003553368111734548,
            0.0035476878352231306,
            -0.0035008482313809565,
            0.003470421931344436,
            0.0034118088069179297,
            -0.003397810364609835,
            0.0033659613060606905,
            -0.0033510663910096975,
            -0.0033401358861044946,
            -0.003339208781204856,
            -0.003282152948455293,
            -0.0032112581940963807,
            -0.0032055744202567735,
            0.0031568968041719974,
            0.0031556763607285317,
            0.0031163106774173845,
            0.0030180352592333363,
            -0.0029739625983805093,
            0.002911684805849212,
            0.0029103756347339587,
            -0.0028781003451152924,
            -0.002867162825027548,
            -0.0027644631456173268,
            0.0026831546040190415,
            0.0026765100926513493,
            -0.002598171712056893,
            0.0025673832031729176,
            0.002550247020468186,
            -0.0024264358112760396,
            0.0023366460203226545,
            0.0022675975660291763,
            -0.0022574032412363072,
            -0.0021859850544687894,
            0.002169112254567295,
            -0.00215024060265463,
            -0.002114394080924186,
            -0.0020988589390090913,
            0.002077703314512373,
            -0.0020680500172765015,
            0.0020579592072204407,
            -0.0020182642673016267,
            -0.001998090981958868,
            -0.0019948593519653643,
            0.0019648316653402722,
            -0.0019080648971002046,
            0.0019024333857989462,
            -0.0018892662922225772,
            -0.0018367523474268265,
            -0.0018162765665259166,
            -0.0017982068853455507,
            -0.0017932401675987899,
            0.0017922162418428874,
            0.00176964257327655,
            0.0017678463745503933,
            0.0017296366405280268,
            -0.0016999558959902641,
            0.0016991041401938688,
            0.0016904610330799145,
            0.0016225446939055527,
            -0.0015767477122255213,
            -0.001538003767637264,
            -0.0015243591429748833,
            -0.0015193576414665906,
            -0.0015150892951499937,
            -0.001477508650947301,
            0.001477123919269495,
            -0.0014749886899335233,
            0.0014531686481361042,
            -0.00143844371539011,
            -0.0014314291738112984,
            -0.0014313543127501722,
            -0.0014047726937016984,
            0.001398110101165812,
            0.0013927179563257277,
            0.001372717992849591,
            -0.0013468804771912854,
            0.0013322973341386654,
            -0.001292451722892466,
            0.0012837945339548278,
            0.001270258924124046,
            -0.001260004275020652,
            0.0012344952229237463,
            0.0012336573817766916,
            0.0012314269543494277,
            -0.0011599966348582102,
            0.0011526242148131689,
            0.0011455379059473723,
            -0.001123617539392535,
            0.0011207268717489459,
            -0.0011150726860258177,
            0.0010866434437183767,
            0.0010829652310342262,
            -0.0010436848635243705,
            0.0009773600614937429,
            -0.0009681892517874202,
            0.0009653756612252486,
            -0.0009580396507798497,
            0.0009061705327727885,
            0.0008776656973403324,
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            0.0008143943626330638,
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            0.0007556967603701849,
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            -0.0006964839014836453,
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            -0.0006515655402794537,
            0.0006442963879376055,
            -0.0006429415240567694,
            0.0006326892676418653,
            -0.000612481055330278,
            0.000608175173013082,
            -0.0006013429964907639,
            0.0005956133148163609,
            0.0005888446784625746,
            -0.0005886517434371599,
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            0.0005637490177241282,
            -0.0005622427300827274,
            -0.0005507034564317908,
            -0.0005013159086870451,
            -0.0004666017709841556,
            0.0004490706726018206,
            -0.00044087498447627243,
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            0.00040590418187136926,
            0.00040442278940470673,
            0.000403865789588082,
            -0.0003881576861263351,
            0.0003528826455444473,
            -0.0003473503901918253,
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            0.00033173845192847266,
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            0.00029556846402530295,
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            -0.00021771670300549538,
            -0.00019999999999952307,
            -0.0001997615856274913,
            -0.00018514987706026026,
            0.00017697029876066487,
            -0.00017471927798288765,
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            0.00016802330347257067,
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            0.00016207753035233025,
            -0.0001479763123744797,
            0.00014232150875487424,
            -0.00013890489652771814,
            0.00013039104255221953,
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            -0.0001241270305711003,
            -0.00011717760930461384,
            -0.00011045195732626652,
            -0.0001049447694541503,
            -9.861507385799438e-05,
            9.65006830399337e-05,
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