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Buy Alkem Laboratories at a price target of Rs 2307.
The current market price of Alkem Laboratories is Rs 2,091.95.
Anand Rathi has a buy call on Alkem Laboratories with a target price of Rs 2,307.
Time period given by the brokerage is one year when Alkem Laboratories price can reach the defined target.
We are sanguine about Alkem’s prospects, considering its capability for healthy revenue and profit generation, driven by a focus on brand leadership in the acute segment, the rising contribution from its chronic division and a ramp-up in its US business. We expect revenue and earnings CAGRs over FY18-20 of respectively 16 per cent and 38 per cent. We retain our Buy rating, with a revised price target of Rs 2,307.
Domestic formulations: In its domestic business (about 72 per cent revenue share) Alkem is expanding operations through product launches and moving into new therapy areas. Also, it has strengthened its field force, adding about 2,000 MRs in the last two years, to its present field-force strength of about 8,000. It would look to build upon its growing presence in the chronic therapy segments of neuro/CNS, dermatology, cardiology and anti-diabetics, simultaneously maintaining its leading position in the acute therapy segments of anti-infectives, gastro-intestinals, pain & analgesics and vitamins. We expect a 14 per cent revenue CAGR over FY18-20 in its domestic formulations, backed by volume growth, the rising chronic share, its strong marketing network and product launches.
Launches to drive US formulations: The US (about 21 per cent revenue share) is the second-largest market for Alkem. Here, it is looking to gear up its pace of ANDA filings through its strong focus on R&D, capitalising on in-licensing opportunities and strategic alliances and partnerships to enhance its capabilities and product range. So far, it has filed 107 ANDAs (47 Para IV), of which 49 have been approved (incl. six tentatively, one NDA). Its US formulations would clock a 17 per cent revenue CAGR over FY18-20, considering 8-10 launches.
Valuation: We maintain a Buy on the stock, with a revised target of Rs 2,307 based on 22x FY20e EPS.
Risks: Delay in US FDA approvals, currency fluctuations, more products under price control in India.
Inclusivity is a great, beautiful thing.
A wedding store in Portishead, Bristol, has been praised on Twitter for its all-embracing attitude to women with physical disabilities. The window of the shop, known as the White Collection Bridal Boutique, features a mannequin in a wedding dress, sat in a wheelchair decorated with greenery.
The scene was captured by Beth Wilson, 36, who herself is a wheelchair user, and tells Metro.co.uk it’s the ‘first time’ she’s seen one displayed in a shop window this way (not counting mobility shops).
‘This is the first time I’ve seen a wheelchair in a shop window like this (mobility shops not included) and it was so surprising to see and made me feel represented.
‘I’ve been using a chair for about five years now – not full-time, but usually when I leave the house. I think most disabled people experience inaccessibility often when they go out; I know I do, pretty much every time I go anywhere.
Beth also complimented the store’s creative use of greenery on the chair.
‘Mobility aids are also often portrayed as negative things that people want to hide when actual mobility aids like wheelchairs give us freedom.
Beth, who lives in Portishead, believes there’s a lack of representation for people with disabilities in the fashion world.
She doesn’t currently need a wedding dress herself, but messaged the store when she got home, to tell them how much she appreciated their display.
‘So often disabled people feel invisible, because we don’t see ourselves in the media much and especially not modelling beautiful clothes,’ she said.
Responses on social media have been very positive, with one user saying the dress ‘looks fabulous with the chair’.
Another said she’d noticed this in a shop on TV once, but had ‘never seen any such thing in real life’.
‘I don’t need a wedding dress, but if I did I’d definitely be far happier about going to a shop where I knew that I’d be accepted, wheelchair and all,’ Beth said.
Laura Allen, owner of the shop, has gotten in touch with Metro.co.uk and told us: ‘This is fantastic news, lovely to hear that the window is being perceived well.
Redondo, including Preston Faecher (4), celebrates their come from behind win against San Pedro in a non-league football game Friday at Redondo Union. Redondo won 25-24 after trailing 7-17 at halftime. Friday, September 27, 2013, Redondo Beach, CA.
A wild and spirited second half shifted what was once a straight-forward, error-free San Pedro showcase into a triumph for Redondo.
It started with recovering an onside kick, and then recovering a fumble. Then Redondo’s offense took over during a 25-24 come-from-behind nonleague victory over San Pedro on Friday night at Redondo.
Redondo (4-1) trailed 17-7 at halftime, then opened the second half with an onside kick, which Zane Zent recovered. The play did not result in a score, but served notice that it might be a different Redondo team than the one that showed up in the first half.
The momentum shift was subtle at first. A heavy pass rush by Cedric Muzik led to intentional grounding on San Pedro from its own end zone, when meant a safety, and Redondo pulled to within 17-9 early in the third quarter.
But San Pedro’s Chris Lauro promptly recovered a Redondo fumble, and three plays later Albert Martinez caught a 31-yard touchdown pass from Mike Hannifin. San Pedro led 24-9 with 7:19 left in the third quarter.
Redondo had to overcome an interception and a punt on its next possessions before it got rolling.
A 13-play drive culminated in a 25-yard field goal by Colin Castillo, pulling Redondo to within 24-12 as time expired in the third quarter.
But on San Pedro’s next possession, it fumbled on the snap and Alex Maimot recovered on the Redondo 49-yard line.
Then Harrison Faecher took over.
Faecher’s 33-yard pass play to Marcel Myers helped set up his own 15-yard touchdown run on a scramble, pulling Redondo to within 24-19 with 8:28 left in the game.
Redondo’s defense forced San Pedro (3-1) to punt, then Redondo marched down field. Faecher converted a fourth-and-1 with a quarterback sneak to keep the drive going. Then for the second time in the game, Faecher fooled the San Pedro defense with an option-keeper. He faked a handoff to Stephon Sudduth, then rambled 25 yards for a touchdown with 3:46 left in the game.
Redondo’s 2-point-conversion attempt failed, but it held a 25-24 lead.
San Pedro made it to midfield before Salesi Fifita came down with an interception on fourth-and-10 to put the game away. Faecher also fooled the defense on the same in the second quarter, when he rambled 30 yards for a touchdown.
Faecher finished with nine rushes for a team-leading 81 yards and three touchdowns. Through the air, Faecher was 28 for 38 for 237 yards and no touchdowns with one interception.
San Pedro was in control early, taking a 10-0 lead when Pete Palacios’ 15-yard run set up Arron Scognamillo’s 8-yard touchdown run with 40 seconds left in the first quarter.
In the second quarter, San Pedro had a 14-play, 81-yard drive, highlighted by Palacios’ 12-yard run and capped by Scognamillo’s 5-yard run.
Palacios led San Pedro with 13 carries for 65 yards and Monoah Tuiasosopo had seven rushes for 41 yards. Tuiasosopo also had an interception for the Pirates.
The come-from-behind win gives Redondo a head of steam as it goes into a bye week and then Bay League play.
Join us for an interactive weekend where you can explore the themes of ancient Mythology and how they relate to your story today.
Leave with your questions answered.
Let your senses be excited, let your mind be stretched, let your future be ignited.
Get inspired, invigorated and uncover the purpose of YOUR story.
Voni Dyson (Holistic Life Coach) and Clem McGrath (Spiritual Teacher) will guide you through a weekend like nothing you have experienced! Get the opportunity to truly step outside of your normal reality and make choices that will allow your life to flourish.
Darren Fletcher is one of the first names on the Scotland teamsheet but, at club level, he is having to come to terms with being a fringe figure.
The 23-year-old midfielder is set to make only his third start of the season tonight as Manchester United host Sporting Lisbon - but you will not hear a word of complaint from him.
A combination of niggling injuries and the impressive recent form of Brazilian new boy Anderson have kept Fletcher on the sidelines for much of the campaign so far.
Indeed, he was not due to begin the away game against Dynamo Kiev last month but ended up being called in at the last minute after Patrice Evra pulled out in the warm-up.
Yet Fletcher remains as committed to United as he has ever been. And, while he accepts a large degree of patience will be required over the coming months, the Edinburgh-born star knows his presence will be felt at some point.
"Obviously, you want to play in every game," he said. "The manager has a lot of choice and you can't really take someone out of the team when they have been in good form.
"Unfortunately, I have had a couple of injuries when I might have got a chance. You have to give credit to Anderson, though. He has come in and done well for someone so young.
"I just have to be patient. I need to keep fit and take every chance to remind people I am good enough to play at this level."
United's preparations for tonight's game at Old Trafford were interrupted yesterday when Sir Alex Ferguson was charged with using abusive or insulting language towards referee Mark Clattenburg during Saturday's Premiership defeat at Bolton.
Ferguson is likely to be fined for his outburst - although if he does receive a touchline ban, it could take effect for the crucial game with Liverpool on December 16, five days after the date set for a hearing.
Daron Acemoglu is the Charles P. Kindleberger Professor of Applied Economics in the Department of Economics at the Massachusetts Institute of Technology and a member of the Economic Growth Program of the Canadian Institute of Advanced Research. He is also affiliated with the National Bureau of Economic Research, the Center for Economic Performance, the Center for Economic Policy Research, and Microsoft Research Center. His research covers a wide range of areas within economics, including political economy, economic development and growth, human capital theory, growth theory, innovation, search theory, network economics and learning.
Scientists studying the soil beneath a leaking Hanford nuclear waste storage tank have discovered more than 100 species of bacteria living in a toxic, radioactive environment that most would have thought inhospitable to all forms of life.
"Even in some of the most contaminated zones, we found a few living organisms," said Fred Brockman, a microbial ecologist at the Pacific Northwest National Laboratory in Richland. Brockman is presenting the findings today at the American Society for Microbiology's annual meeting in New Orleans.
For most living creatures, the nuclear and chemical waste in the underground storage tanks on the Hanford Nuclear Reservation is the deadliest mixture of toxins and radioactive muck on the planet.
For certain bacteria, however, this toxic goop left over from decades of nuclear weapons production appears to be just a second home.
"Scientifically, it's pretty interesting stuff," said Jim Fredrickson, Brockman's colleague on this project and a fellow microbiologist at the lab. "The material in the tank is self-boiling and quite hot, so it's not just radioactive and harsh chemicals but also in extreme heat."
The waste in the Hanford tanks is made up of highly radioactive cesium, strontium and various other toxic chemicals left over from the World War II bomb works. About 53 millions gallons was stored in 177 underground tanks, some of which have leaked an estimated 1 million gallons into the surrounding soil of the Columbia Basin.
The U.S. Department of Energy now wants to empty and close 40 single-shelled Hanford tanks by 2006. Critics of the department and state Ecology officials are concerned that this could be too hasty an agenda and divert energy or resources from the massive clean-up effort still needed to protect against further environmental contamination.
Brockman, Fredrickson and their colleagues piggybacked their microbial studies on efforts by DOE and its waste tank managers to track the leaks. They asked to study sediment samples collected in 2000 from boreholes dug around one of the leaking tanks.
"I believe this is the most radioactive soil that's ever been looked at for microorganisms," Brockman said. "If you were to just drop these same bacteria directly into this tank waste, none of them would survive."
But on the outside of the tanks, exposed to the same deadly mixture, some bacteria learned to survive.
"One of the most interesting findings was a strain of Deinococcus," Fredrickson said. It's a type of bacteria that's been found in Antarctica and on irradiated meat, he said, but never at Hanford before.
Brockman said they didn't discover any new species of bug -- based on the standard method for identifying species -- but genetic analysis of the Hanford versions of these bacteria indicate they may have at least found some unique new strains.
"These bacteria have learned to shield themselves somehow, to produce proteins or other molecules that protect against the radiation," Brockman said. "Their genes appear to be quite dissimilar (from standard strains of these bacteria)."
Though the Richland microbiologists have nothing to do with the tank clean-up effort and didn't launch the study with that problem in mind, their findings could be of some use. Deinococcus, for example, is able to chemically alter one of the contaminants, chromate, in a way that slows its migration through the soil.
"It's possible that we may learn how to contain the waste biologically, using these kinds of organisms," Fredrickson said.
But for now, Brockman said, the next step will be in figuring out just what kind of microbes they have found, more about their genetics and perhaps identifying some of the novel proteins they produce that allow them to live in such a noxious neighborhood.
The Hanford tank study was largely funded by the Department of Energy's Microbial Genome Program -- the microbial version of the Human Genome Project , which also was also launched by the Department of Energy in the 1980s.
What are the healthiest foods at the supermarket?
Nikki Bezzant talks us through the products that really deliver on nutrition and some others with only a 'health halo'.
When it comes to food, 'processed' doesn't always mean bad, Nikki says.
"Not many of us have got the time to make our own cereal from scratch or roast our own fava beans."
Many products that are marketed with keywords such as 'organic', 'natural', or 'no refined sugar', don't deliver on nutrition, she says.
"This is a really good source of protein and a good source of protein you can have throughout the day … spreading it throughout the day is really key. It tastes delicious, it's unsweetened and it's nice and thick and creamy. We liked everything about it, really. We think it's great."
"Short of crumbing your own at home, this is a really good product. It's a convenient food that is pretty good, and tasty, as well."
"They're super high in sugar… They stick to your teeth something shocking. And that is appallingly bad for dentail heealth, especially for kids. These have got more sugar than some of the fruit bars with added sugar in them."
"There's no difference, really, between those and potato chips"
"It should tell you in the name. It's probably not the best breakfast for you."
These also contain the old-fashioned sweetener manitol which is known to have laxative effects, Nikki says.
"There's enough in more than two of these to give you a little bit of an issue."
While agave is lower-GI than sugar, this is 90 precent fructose – a kind of sugar with its own issues, she says.
"Wholesome" is not really the right word."
The full list will be published in the January 2018 issue of the Healthy Food Guide.
How did Australia go from a place where its migrant hostels fostered some of the world’s most famous bands to one where the detentions centres it presides over are described as “hell on Earth”?
Prior to May 1992, there was no mandatory detention in Australia.
At most, a couple of hundred people came via boat to seek asylum each year. They were housed in places such as the Villawood Migrant Hostel.
Some of the migrants who first met and jammed at these hostels went on to form iconic bands such as the Easybeats and AC/DC. It was the post-war era, when immigration from Europe was encouraged.
In the 1970s, people started arriving on boat from Asia, particularly from Vietnam and Cambodia.
In response, a section was constructed in the Villawood centre to house people awaiting deportation in 1976. In 1984, the entire hostel was converted into the Villawood Immigration Detention Centre.
At the time, people who had their application for asylum rejected by the government were able to appeal to the High Court, which granted permanent residency to the vast majority of applicants on “strong compassionate or humanitarian grounds”.
However, in 1989, parliament abolished the means for people to obtain residency through the court system.
These move was accompanied by a racist hysteria whipped up towards Asian “boat people”. The political rhetoric then — like today — was about the need to deter “boat people”.
On June 6, 1990, then-Labor prime minister Bob Hawke, speaking about Cambodian asylum seekers, said on A Current Affair: “We’re not going to allow people just to jump that queue by saying we’ll jump into a boat, here we are, bugger the people who’ve been around the world”.