What is the main difference between Ganoderma lucidum and Ganoderma tsugae fungi in terms of where they grow?

However, most consider Ganoderma. lucidum and G. curtisii to be the same species because of their similar appearance and habitats; they both prefer to grow on hardwoods. In "North American Polypores," practically the bible for wood-decaying poroid fungi, Gilbertson and Ryvarden, do not consider G. curtisii a species separate from G. lucidum. Another fungus that resembles G. lucidum is Ganoderma oregonense, which, like G. tsugae grows on conifers, but is found in the Pacific Northwest and New Mexico. G. oregonense can get up to 1 meter across and has slightly larger spores than G. lucidum and G. tsugae. There are arguments that these four separate species (G. lucidum, G. tsugae, G. curtisii, and G. oregonense) should be considered one species. The reasons for keeping them apart are primarily due to the host specificity of each fungus. Interestingly, if given only either hardwood or conifer wood in culture, each of the four species can grow and produce fruiting bodies, despite their natural occurrence on only one of those substrates.
In 1995, Moncalvo, Wang and Hseu, isolated the DNA of G. tsugae and G. lucidum and found that it was hard to tell the difference between the two species. An even more recent study in 2004 by Hong and Jung, found that G. lucidum from Asia was in its own group, whereas, G. lucidum from Europe and the Americas was more closely related to G. tsugae. Clearly, further investigation into the molecular make up of these two species is needed. For more information about the relationships of the species Ganoderma For more information, see these papers: Moncalvo, J.M., Wang, H. H. & Hseu, R. S. (1995). Phylogenetic relationships in Ganoderma inferred from the internal transcribed spacers and 25S ribosomal DNA sequences. Mycologia 87: 223-238, and Hong, S.G., Jung, H. S. (2004) Phylogenetic analysis of Ganoderma based on nearly complete mitochondrial small-subunit ribosomal DNA sequences.

Ganoderma lucidum, is an interesting shelf fungus that is important as a medicine in the Far East, in places such as China, Japan and Korea. G. lucidum is of particular interest because it has been portrayed as a "fix-it-all" herbal remedy for maladies such as: HIV, cancer, low blood pressure, high blood pressure, diabetes, rheumatism, heart problems, paralysis, ulcers, asthma, tiredness, hepatitis A, B, and C, insomnia, sterility, psoriasis, mumps, epilepsy, alcoholism, and the list goes on. These claims are mostly made by the people who are selling G. lucidum herbal supplements, but G. lucidum, also known as Reishi, ling chih, and ling zhi has a long history of being used as an herbal remedy. We will get to that later.
First, how do you identify Ganoderma lucidum? Ganoderma is a member of the Polypores, a group of fungi characterized by the presence of pores, instead of gills on the underside of the fruiting body. G. lucidum, considered by many mycophiles to be one of the most beautiful shelf fungi, it is distinguished by its varnished, red surface. When it is young it also has white and yellow shades on the varnished surface, differing from the dull surface of Ganoderma applanatum, the artist's conk. G. lucidum is a saprophytic fungus that tends to grow more prolifically in warm climates on decaying hardwood logs and stumps. This feature helps to distinguish it from a similar looking Ganoderma tsugae, which also has a beautiful red varnished surface, but only grows on the stumps and logs of conifers, especially hemlock (as you might guess from the name). Another distinguishing characteristic is the flesh of G. tsugae is white whereas the flesh of G. lucidum is brown. Besides the shelf form, both G. tsugae and G. lucidum can be stalked. The spore prints of both species are brown and the spores are very similar in size and shape.
Ganoderma curtisii is considered by some mycologists to be a different species because of its brighter yellow colors and geographic restriction to the southeaster United States.

Mycologia 96: 742-755.
Ganoderma lucidum, considered rare and hard to find in nature in China and Japan, is now commonly cultured. It can be cultured on logs that are buried in shady, moist areas. G. lucidum can also be inoculated onto hardwood stumps. Under commercial cultivation conditions, G. lucidum is normally grown on artificial sawdust logs, as shown to the right. We'll cover this cultivation method in more detail in a later Fungus of the Month. Other methods of cultivating G. lucidum and many other fungi can be found in Paul Stamets' book, "Growing Gourmet and Medicinal Mushrooms"
Now let's look at the medicinal uses of G. lucidum or Reishi. If you feel the fruiting bodies, you'll notice that they're very hard, so no one tries to eat them like most (softer) mushrooms-- too tough! It has been used as an herbal remedy for such things as health, recuperation, longevity, wisdom and happiness for centuries in Asian traditional medicine. The first historical mention of G. lucidum was during the rule of the first Chinese emperor, Shin-huag of the Ch'in Dynasty, when the fungus's medicinal uses are first described. In fact, a Reishi Goddess, known as Reishi senshi, was worshipped because she would bestow health, life and eternal youth.
There are two different types of Reishi, the traditional wide, shelf-like fruiting body and the antler shape, known as Rokkaku-Reishi. The antler shape arises from varying carbon dioxide levels and low light. These two types are rumored to have different healing characteristics. Recently, there have been a large amount of scientific papers published with experiments attempting to quantify the effect of G. lucidum on the human body. The fungal extract has been shown to act on immune system cells, to work against herpes virus, to lower cholesterol and stop cell proliferation.
Unfortunately, while reading these papers it seems important to remind you that we are still not sure if G. lucidum and G. tsugae are separate species.
Although the molecular make up has yet to be determined conclusively, several biologically active compounds from G. lucidum have been characterized.

- Ganoderma tsugae - A polypore which grows on conifers, especially hemlock, giving it its common name, hemlock varnish shelf. Similar in appearance to Ganoderma lucidum and a close relative, which typically grows on hardwoods.
- Kirk PM, Cannon PF, Minter DW, Stalpers JA (2008). Dictionary of the Fungi (10th ed.). Wallingford: CABI. p. 272. ISBN 978-0-85199-826-8.
- Liddell, Henry George & Robert Scott (1980). A Greek-English Lexicon (Abridged ed.). United Kingdom: Oxford University Press. ISBN 0-19-910207-4.
- Karsten, P. 1881. Enumeratio Boletinarum et Polyporarum Fennicarum systemate novo dispositorum. Rev. Mycol. 3:16-18
- Murrill, W. A. 1902. The Polyporaceae of North America, genus I Ganoderma. Bull. Torrey Bot. Club 29:599-608.
- Patouillard, N. 1889. Le genre Ganoderma. Bull. Soc. mycol. Fr. 5:64-80.
- Atkinson, G. F. 1908. Observations on Polyporus lucidus Leys and some of its Allies from Europe and North America. Botanical Gazette 46:321-338.
- Adaskaveg, J. E. 1986. Studies of Ganoderma lucidum and Ganoderma tsugae (Delignification, Mating Systems, Root Rot, Cultural Morphology, Taxonomy). Dissertation. The University of Arizona.
- Murrill, W. A. 1908. Agaricales (Polyporaceae). North Amer. Flora 9:73-131.
- Karsten PA. (1881). "Enumeratio Boletinearum et Polyporearum Fennicarum, systemate novo dispositarum". Revue mycologique, Toulouse (in Latin). 3 (9): 16–19.

Maciá-Vicente, H.B. Bode, and M. Piepenbring. 2016. “Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles.” Phytochemistry 127:29–37.
- Hapuarachchi, K., T. Wen, C. Deng, J. Kang, and K. Hyde. 2015. “Mycosphere Essays 1: Taxonomic Confusion in the Ganoderma lucidum Species Complex.” Mycosphere 6:542–559.
- Jin, X; Ruiz Beguerie, J; Sze, D. M; Chan, G. C (2016). "Ganoderma lucidum (Reishi mushroom) for cancer treatment". Cochrane Database of Systematic Reviews. 4: CD007731. doi:10.1002/14651858.CD007731.pub3. PMC 6353236. PMID 27045603.
- "Horse chestnut tree diseased" (Press release). The Anne Frank House. Archived from the original on 3 October 2006. Retrieved 2006-11-17.
- Kuo M., MushroomExpert.Com, Ganoderma tsugae. (2004, February). Retrieved June 15, 2007.

Ganoderma is a genus of polypore fungi in the family Ganodermataceae that includes about 80 species, many from tropical regions. They have a high genetic diversity and is used in traditional Asian medicines. Ganoderma can be differentiated from other polypores because they have a double-walled basidiospore. They may be called shelf mushrooms or bracket fungi.
The genus Ganoderma was established as a genus in 1881 by Karsten and included only one species, G. lucidum (Curtis) Karst. Previously, this taxon was characterized as Boletus lucidus Curtis (1781) and then Polyporus lucidus (Curtis) Fr. (1821) (Karsten 1881). The species P. lucidus was characterized by having a laccate (shiny or polished) pileus and stipe, and this is a character that Murrill suspected was the reason for Karsten's division because only one species was included, G. lucidum . Patouillard revised Karsten's genus Ganoderma to include all species with pigmented spores, adhering tubes and laccate crusted pilei, which resulted with a total of 48 species classified under the genus Ganoderma in his 1889 monograph. Until Murrill investigated Ganoderma in North America in 1902, previous work had focused solely on European species including, for example, G. lucidum, G. resinaceum Boud. (1890) and G. valesiacum Boud. (1895).
Ganoderma are characterized by basidiocarps that are large, perennial, woody brackets also called "conks". They are lignicolous and leathery either with or without a stem. The fruit bodies typically grow in a fan-like or hoof-like form on the trunks of living or dead trees. They have double-walled, truncate spores with yellow to brown ornamented inner layers.
The genus was named by Karsten in 1881. Members of the family Ganodermataceae were traditionally considered difficult to classify because of the lack of reliable morphological characteristics, the overabundance of synonyms, and the widespread misuse of names.

Some Ganoderma species can cause major long-term crop losses, especially with trees:
- G. orbiforme (= G. boninense), G. zonatum and G. miniatocinctum are responsible for basal stem rot disease in Asian oil palm plantations.[better source needed]
- G. philippii and G. pseudoferreum are responsible for the root rot of cacao, coffee, rubber and tea trees.
Ganoderma are wood-decaying fungi with a cosmopolitan distribution. They can grow on both coniferous and hardwood species. They are white-rot fungi with enzymes that allow them to break down wood components, such as lignin and cellulose. There has been significant research interest on the wood-degrading enzymes of Ganoderma species for industrial applications, such as biopulping and bioremediation.
For centuries, Ganoderma species have been used in traditional medicine in many parts of Asia. These species are often mislabeled as 'G. lucidum', although genetic testing has shown this to be multiple species such as G. lingzhi, G. multipileum, and G. sichuanense. Several species of Ganoderma contain diverse phytochemicals with undefined properties in vivo, such as triterpenoids and polysaccharides, an area of investigation under basic research.
Although various Ganoderma species are used in traditional medicine for supposed benefits and have been investigated for their potential effects in humans, there is no evidence from high-quality clinical research that Ganoderma as a whole mushroom or its phytochemicals have any effect in humans, such as in treating cancer.
- Ganoderma applanatum - Also known as the artist's conk. An infestation of this species was the main factor in the loss of the Anne Frank Tree.
- Ganoderma lingzhi - Also known as red reishi, a mushroom used extensively in traditional Asian medicine.
- Ganoderma lucidum - A polypore with limited distribution in Europe and parts of China, often misidentified on products labeled reishi or lingzhi that actually contain Ganoderma lingzhi, because of the persistence of outdated naming conventions.
- Ganoderma sinense - Also known as black reishi or zizhi.

What is Ganoderma Lucidum (Lingzhi mushroom/ Reishi mushroom)?
Ganoderma lucidum, an oriental fungus, has a long history of use for promoting health and longevity in China, Japan, and other Asian countries. It is a large, dark mushroom with a glossy exterior and a woody texture. The Latin word lucidus means “shiny” or “brilliant” and refers to the varnished appearance of the surface of the mushroom. In China, G. lucidum is called lingzhi, whereas in Japan the name for the Ganodermataceae family is reishi or mannentake.
What is Ganoderma Lucidum (Lingzhi mushroom/ Reishi mushroom)?
Ganoderma Lucidum (Latin), commonly known as Lingzhi mushroom (Chinese) or Reishi mushroom (Japanese) is a well-known representative of mushrooms that have been used in traditional Chinese medicine for many centuries for the prevention and treatment of many human diseases.
Traditionally, the fruit body of Ganoderma Lucidum has been possible to obtain large quantity of spores produced by the fruit body and it has recently been recognized that the spores of Ganoderma Lucidum possess more potent effect than the fruit body.
What is Ganoderma Lucidum Spores Powder？
Why Ganoderma Lucidum Spores Powder is Better？
The Ganoderma Lucidum spore has two thick layers of chitin outer wall that is difficult to be digested by human stomach acid. It is only upon cracking/ breaking the two thick layers of the wall that the active ingredients of the Ganoderma Lucidum spores powder can be optimally absorbed by the human body.
Two ways to break the wall
Physical wall breaking mainly destroys the spore wall of the Ganoderma Lucidum by mechanical or physical action, however, with this method, a sizable proportion of the active ingredients are easily oxidized and deteriorated when exposed to the air process.
Enzymatic breaking is the use of biological enzymes to slowly hydrolyze the cell wall of Ganoderma Lucidum spores, the process is mild, effective active ingredient damage is minimized, not easy to oxidize and degenerate, there are no harmful substances, and has a high breaking rate.
Most spores powder available in the market are produced by the physical wall breaking method.

About Reishi Mushroom
The reishi mushroom (Ganoderma lucidum) is a fungus that predominantly grows in tropical and subtropical woodlands in the Asian continent. The word Ganoderma lucidum was derived from two Latin words, ‘Gan’ which means shiny and ‘Derm’ meaning skin and ‘Lucidum’ with the meaning ‘brilliant’. This term describes the glossy appearance of the mushroom. The reishi mushroom bears the nickname “queen of mushrooms” as it has been revered by Chinese people for ages. In China, it is popularly known as “Ling Zhi” which means a spiritual or miraculous mushroom, “Rui-Zhi”, and “Chi-Zhi. In Japan, it is referred to as “Reishi”, “Sachitake” or “Mannatake”. Americans commonly refer to it as Reishi while the Koreans named it “Youngzhi”, while it is wideley referred to as the “mushroom of immortality”. This mushroom belongs to the family Ganodermataceae and the genus Ganoderma. The term reishi is usually used when naming a group of closely related species of mushrooms that grow in woodlands particularly, Ganoderma tsugae, Ganoderma sinesis and Ganoderma lucidum. The species Ganoderma lucidum is the one with the highest demand in the human health realms.
Reishi mushrooms thrive best in the wild, particularly in temperate and humid forests found in the mountains in Asia. The forests are usually located in very remote areas that are free from pollution that has clouded a majority of cities today. The reishi mushroom is a polypore, a sizeable group of mushrooms that form on dead and decaying hardwood trees. They have tubes on the underside of their cap with white pores that produce a large number of spores within a short time. A single fungus can give rise to not more than three fruiting bodies. The fruiting body can be flat, shaped like a kidney and grows over 8cm in width. Alternatively, it can be tiny and assume the shape of a cloud. The skin of reishi mushrooms has a reddish-brown glossy appearance. However, the colour ranges from black to purple in certain locations. Mature reishi and growing reishi feel soft, like a sponge.

Their terpenoid profile however shows considerable variance; G. lucidum possess a significantly larger quantity and variety of triterpenes than G. sinense. This is very interesting because G. sinense was, when available, used interchangeably with G. lucidum throughout history due to offering many of the same potential benefits.
From a scientific standpoint, many of these benefits are attributed to the triterpenes of G. lucidum, such as anti-inflammatory, liver-protective and tumour-inhibiting properties, yet G. sinense contains a comparatively lower percentage of these compounds. This is also why G. sinense tastes nowhere near as bitter as G. lucidum, offering a very mild taste by contrast.
That said, Purple Reishi contains a notable amount of the thoroughly well researched Ganoderic Acid A, and some novel terpenoids have been established from ethanol extractions of the fruiting body. Two lanostane triterpenes unique to this species were discovered in 2007, followed by nine new terpenoids that were isolated in 2011. Amongst these compounds, some exhibited anti-cancer mechanisms and others were influential in regulating liver enzymes responsible for the metabolism of toxins, drugs and their safe elimination from the body.
However, G. sinense contains a more dominant presence of β-d-glucans, in particular the complex, branched polysaccharide GSP-6B, which has shown impressive in vitro immune-modulation activity. Other biologically active polysaccharides named GSA and GSW from G. sinense have been analysed via both in vitro and in vivo research and have revealed anti-tumour properties as well as the ability to regulate macrophage activity and even modulate populations of gut microbiota.
According to the system of Chinese medicine, both Purple and Red Reishi were synonymous with the moniker ‘Lingzhi‘. In this context, ling means ‘divine’ and zhi means ‘mushroom’. Both were regarded as supernatural medicines that confer immortality to those who ingested them. However, despite their shared status there were times when the two species needed to be distinguished from one another, and so the name ‘Zizhi‘ was assigned to Purple Reishi, simply meaning ‘sacred purple mushroom’.

Until recently, the genus was divided into two sections – Ganoderma, with a shiny cap surface (like Ganoderma lucidum), and Elfvingia, with a dull cap surface (like Ganoderma applanatum).
Phylogenetic analysis using DNA sequence information have helped to clarify our understanding of the relationships amongst Ganoderma species. The genus may now be divided into six monophyletic groups:
- G. colossus group
- G. applanatum group
- G. tsugae group
- Asian G. lucidum group
- G. meredithiae group
- G. resinaceum group
With the rise of molecular phylogenies in the late 20th century, species concept hypotheses were tested to determine the relatedness amongst the nuanced morphological variabilities of the laccate Ganoderma taxa. In 1995, Moncalvo et al constructed a phylogeny of the rDNA, which was the universally accepted locus at that time, and found five major clades of the laccate species amongst the 29 isolates tested. It turned out that G. lucidum was not a monophyletic species, and further work needed to be done to clarify this taxonomic problem. They also found that G. resinaceum from Europe, and the North American 'G. lucidum', which Adaskaveg and Gilbertson found to be biologically compatible in vitro, did not cluster together. Moncalvo et al. reject biological species complexes as a sole tool to distinguish a taxon, and suggested using a combination between biological and phylogenetic species concepts to define unique Ganoderma taxa.
In 1905, American mycologist William Murrill delineated the genus Tomophagus to accommodate the single species G. colossus (then known as Polyporus colossus) which had distinctive morphological features that did not fit in with the other species. Historically, however, Tomophagus has generally been regarded as a synonym for Ganoderma. Nearly a century later, phylogenetic analyses vindicated Murrill's original placement, as it has shown to be a taxonomically distinct appropriate genus.

These fungi have been extensively applied in traditional Chinese medicine (TCM) up to the present day (Chang 2000; Chang and Wasser 2012; Hobbs 1995; Ying et al. 1987) and are becoming more and more popular also in other parts of the world where they are used as a source for medicinal compounds and therapeutic adjuvants, or as health food supplements. They show a wide range of bioactivities including anti-cancer, anti-inflammatory, antiviral and immuno-enhancing effects (Grienke et al. 2014; Molitoris 2005; Paterson 2006). The large number of scientific studies focusing on their bioactivity (Khatun et al. 2011; Lo and Wasser 2011; Xu et al. 2010; Zhao 2013; Zhong and Xiao 2009; Zhou et al. 2011), secondary metabolite production (Hwang et al. 2013; You et al. 2013) and genomics (Floudas et al. 2012; Liu et al. 2012) is therefore not surprising.
Secondary metabolites of medicinal polypores have been the focus of many studies (Grienke et al. 2014; Zjawiony 2004), but the importance of fungal strain for bioactivity and metabolite production has not been investigated so far. Strain-specific differences in bioactivities (on the function of macrophages) were detected for different strains of the Ascomycete Ophiocordyceps sinensis, whose fruit bodies are highly praised as traditional remedy (Meng et al. 2013). Distinct strain differences are also known for anamorphic ascomycetes, e.g. for the secondary metabolite production of Fusarium avenaceum, where substrate is playing an additional important role in the regulation of secondary metabolite biosynthesis (Sørensen and Giese 2013).
Species delimitation of polypores was long based upon macro-morphological and ecological characters. However, these classical morphological species concepts have proven to be too wide for many important medicinal polypore species, e.g. for Ganoderma lucidum, G. applanatum, or Laetiporus sulphureus (Banik et al. 2010; Banik et al. 2012; Hseu et al.

Purple Reishi (Ganoderma sinense) is a polypore mushroom that is native to Asia, specifically to China and Japan. It grows on both broadleaf trees and conifers but is very rare and notoriously difficult to find in the wild. Its modern scarcity may be partly due to industrial deforestation and the dramatic loss of biodiversity in some of its native forests, although historically it was never found in any great abundance.
Traditionally it was often used interchangeably with Red Reishi (Ganoderma lucidum). It is for this reason that both species are referred to as ‘Lingzhi‘ in traditional Chinese medicine. They both play a very similar ecological role within the forest and share a broad number of health benefits, but in truth the two species are notably different in a number of ways.
While this mushroom usually exhibits a dark purple hue, it also commonly presents dark brown to almost black colouring. It is typically much darker than Red Reishi, has a less bitter, slightly sweet taste and a different arrangement and concentration of biologically active compounds.
As already mentioned, this species was a rarity throughout history. It therapeutic potency was formidable, yet before it was cultivated the wild mushroom was sparse and foraging it was a challenge. Thankfully, the cultivation of this species has developed into a fine art when done thoroughly and conscientiously.
Purple Reishi can be grown using the same methods as Red Reishi cultivation, but in an attempt to save time and money, many growers will cut corners and yield small, medicinally inferior fruiting bodies. However, if wild-simulated Di Tao practices are adhered to, mushrooms exhibiting the qualities and properties of the finest wild specimens can be produced. To learn more about these practices, read the Methods of Cultivation chapter on our main page about Reishi.
As with Red Reishi (Ganoderma lucidum), Purple Reishi contains hundreds of different compounds that collaborate synergistically to produce a collective ‘entourage effect‘. There are many proteins and fatty acids, sterols, polyphenols and trace elements, but the compounds understood to be the most powerful and have a ‘directing’ influence over the medicinal activity, are the fungal polysaccharides and triterpenes.
Comparisons between G. sinense and G. lucidum show that overall, their polysaccharide and especially β-d-glucan content is very similar with no striking differences between the two.

The superior Enzyme breaking process was patented and commercialized in 1998, producing Ganoderma Lucidum spores powder of the highest quality and efficacy. It is estimated that only 2% of the Lingzhi spores powder in the market are produced using the patented Enzyme “cracking” process.
Differences Between Spore Powder and Spore Oil
Ganoderma Lucidum spore oil is a lipid active substance extracted from the broken Ganoderma Lucidum spore powder by supercritical CO2 fluid extraction technology, and is the essence of Ganoderma Lucidum extract. The main components of Ganoderma Lucidum spore oil are Ganoderma Lucidum triterpenoids, ergosterol, unsaturated fatty acids, etc. The high-graded Ganoderma Lucidum spore oil also contains precious components such as peroxyergosterol.
At present, Ganoderma Lucidum spore oil extraction by supercritical CO2 fluid technology generally extracts the oil from broken spores by mechanical means, or intact spores softening by high temperatures, followed by granulating and extraction. Ganoderma Lucidum spore oil extracted from spores broken by mechanical means is of low physiological activities, and thereby with poor quality, because a part of the bioactive substances obtained are spoiled by oxidation during the mechanical process.
Major Bioactive Components - Triterpenes and Polysaccharides
Fungi are remarkable for the variety of high-molecular-weight polysaccharide structures that they produce, and bioactive polyglycans are found in all parts of the mushroom. Polysaccharides represent structurally diverse biological macromolecules with wide-ranging physiochemical properties. Various polysaccharides have been extracted from the fruit body, spores, and mycelia of lingzhi; they are produced by fungal mycelia cultured in fermenters and can differ in their sugar and peptide compositions and molecular weight (e.g., ganoderans A, B, and C). Ganoderma Lucidum polysaccharides (GL-PSs) are reported to exhibit a broad range of bioactivities, including anti-inflammatory, hypoglycemic, antiulcer, antitumorigenic, and immunostimulating effects.

- Smith BJ, Sivasithamparam K (2003). "Morphological studies of Ganoderma (Ganodermataceae) from the Australasian and Pacific regions". Australian Systematic Botany. 16 (4): 487–503. doi:10.1071/SB02001.
- Ryvarden L. (1985). "Type studies in the Polyporaceae 17: species described by W. A. Murrill". Mycotaxon. 23: 169–198.
- Hibbett DS, Donoghue MJ. (1995). Progress toward a phylogenetic classification of the Polyporaceae through parsimony analysis of mitochondrial ribosomal DNA sequences. Can J Bot 73(S1):S853–S861.
- Hibbett DS, Thorn RG. (2001). Basidiomycota: Homobasidiomycetes. The Mycota VII Part B. In: McLaughlin DJ, McLaughlin EG, Lemke PA, eds. Systematics and evolution. Berlin-Heidelberg, Germany: Springer-Verlag. p 121–168.
- Hong SG, Jung HS (2004). "Phylogenetic analysis of Ganoderma based on nearly complete mitochondrial small-subunit ribosomal DNA sequences". Mycologia. 96 (4): 742–55. CiteSeerX 10.1.1.552.9501. doi:10.2307/3762108. JSTOR 3762108. PMID 21148895.
- Moncalvo, J.-M., Wang, H.-F., and Hseu, R.-S. 1995. Gene phylogeny of the Ganoderma lucidum complex based on ribosomal DNA sequences. Comparison with traditional taxonomic characters. Mycological Research 99:1489-1499.
- Adaskaveg, J. E., and Gilbertson, R. L. 1986. Cultural studies and genetics of sexuality of Ganoderma lucidum and G. tsugae in relation to the taxonomy of the G. lucidum complex. Mycologia:694-705.
- Murrill WA. (1905). "Tomophagus for Dendrophagus".

This strain also differs from temperate strains by a significantly higher temperature optimum, and different growth rates, thus supporting a hypothesis suggesting that tropical species of wood-decay fungi are characterized by a higher temperature optima for growth (30-40°C) than temperate wood decay fungi (20-30°C) (Magan 2008). Growth rates have been shown to be species-specific in Fomes (McCormick et al. 2013), which is further supporting our hypothesis that this lineage represents a distinct species.
Species delimitation is an important issue in medicinal fungi, because the production of bioactive secondary metabolites is first species-specific, and then depending on strain characteristics. Physiological properties, e.g. growth rates and optimum temperature, are generally useful characters for species delimitation in fungi (Jaklitsch 2009) and have been applied for corticoid (Hallenberg and Larsson 1991) and poroid (McCormick et al. 2013) wood-inhabiting Basidiomycota. Also pigments and other metabolites are good indicators for the distinction of fungal taxa (Breheret et al. 1997; Frisvad et al. 2008). The European name Ganoderma lucidum (= Reishi mushroom), for example, has been widely applied on a global scale, but represents several distinct lineages or species (Wang et al. 2012), which differ in their secondary metabolite profiles (Lv et al. 2012). Also Laetiporus sulphureus, which is another important medicinal polypore, includes several lineages representing distinct species with different geographic origin and from different hosts (Banik et al. 2012). Ecological adaptation through host shifts and substratum specialization is likely to be an important mode of speciation and adaptive radiation in polypores (Skaven Seierstad et al. 2013). A successful screening on bioactive secondary metabolites must therefore be based on two stable pillars: first, a reliable species identification followed by an extensive screening for a suitable or ‘best strain’.
Agafonova SV, Olennikov DN, Borovskii GB, Penzina TA (2007) Chemical composition of fruiting bodies from two strains of Laetiporus sulphureus.

Polysaccharides are normally obtained from the mushroom by extraction with hot water followed by precipitation with ethanol or methanol, but they can also be extracted with water and alkali. Structural analyses of GL-PSs indicate that glucose is their major sugar component. However, GL-PSs are heteropolymers and can also contain xylose, mannose, galactose, and fucose in different conformations, including 1–3, 1–4, and 1–6-linked β and α-D (or L)-substitutions. Branching conformation and solubility characteristics are said to affect the antitumorigenic properties of these polysaccharides. The mushroom also consists of a matrix of the polysaccharide chitin, which is largely indigestible by the human body and is partly responsible for the physical hardness of the mushroom. Numerous refined polysaccharide preparations extracted from Ganoderma Lucidum are now marketed as over-the-counter treatment for chronic diseases, including cancer and liver disease.
Terpenes are a class of naturally occurring compounds whose carbon skeletons are composed of one or more isoprene C5 units. Examples of terpenes are menthol (monoterpene) and β-carotene (tetraterpene). Many are alkenes, although some contain other functional groups, and many are cyclic. These compounds are widely distributed throughout the plant world and are found in prokaryotes as well as eukaryotes. Terpenes have also been found to have anti-inflammatory, antitumorigenic, and hypolipidemic activity. Terpenes in Ginkgo biloba, rosemary (Rosemarinus officinalis), and ginseng (Panax ginseng) are reported to contribute to the health-promoting effects of these herbs.
Ganoderma Lucidum is clearly rich in triterpenes, and it is this class of compounds that gives the herb its bitter taste and, it is believed, confers on it various health benefits, such as lipid-lowering and antioxidant effects. However, the triterpene content is different in different parts and growing stages of the mushroom. The profile of the different triterpenes inGanoderma Lucidum can be used to distinguish this medicinal fungus from other taxonomically related species, and can serve as supporting evidence for classification.

Torreya. 5: 197.
- Furtado JS. (1965). "Ganoderma colossum and the status of Tomophagus". Mycologia. 57 (6): 979–84. doi:10.2307/3756901. JSTOR 3756901.
- Ling-Chie Wong, Choon-Fah J. Bong, A.S. Idris (2012) Ganoderma Species Associated with Basal Stem Rot Disease of Oil Palm. American Journal of Applied Sciences 9(6): 879-885 (ISSN 1546-9239)
- Loyd, A. L; Held, B. W; Linder, E. R; Smith, J. A; Blanchette, R. A (2018). "Elucidating wood decomposition by four species of Ganoderma from the United States". Fungal Biology. 122 (4): 254–263. doi:10.1016/j.funbio.2018.01.006. PMID 29551199.
- "FBRI: New Enzymes for Biopulping". Archived from the original on 2009-01-04. Retrieved 2008-11-15.
- Matos AJ, Bezerra RM, Dias AA (September 2007). "Screening of fungal isolates and properties of Ganoderma applanatum intended for olive mill wastewater decolourization and dephenolization". Lett. Appl. Microbiol. 45 (3): 270–5. doi:10.1111/j.1472-765X.2007.02181.x. PMID 17718838. S2CID 20255731.
- Wachtel-Galor, Sissi (2011). "Chapter 9 Ganoderma lucidum (Lingzhi or Reishi)A Medicinal Mushroom". Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. CRC Press Taylor and Francis. ISBN 978-1-4398-0713-2. Retrieved 2017-02-22.
- Hennicke, F., Z. Cheikh-Ali, T. Liebisch, J.G.

Lucid ganoderma contains protein, various amino acids, polyose, fats, terpines, ergosterol, organic acids, aldaloid, adenine, uracil, various enzymes and various trace elements as Ge, etc.
Main Pharmacological Actions:
3. Strengthen the heart
4. Improve immune function
5. Improve adrenocortical function
7. Reduce the excitability of parasympathetic nerves
Tumor Restriction Mechanism
By stimulating the body-intrinsic effector cell* with cytotoxicity, ganoderma lucidum spore promotes the biological activity of retothelium and kills the tumor cells, restricting the growth of tumor or eliminating tumor.
1. Activates effector cells of body, enhances the ability of body to kill tumor and of oncolysis, raises the activity of damaging the tumor for over 80%.
2. Induce the secretion and synthesis of cells factor, enhances the ability of body to kill tumor, activates effector cells, and protects normal cells.
3. Restrains immune suppressor factor produced by tumor cells, exposes tumor cells to killer cells.
4. Restrains tumor cells from growing.
5. Repairs and enhances the sensibility of body to cancer effector, enhances adaptability of body.
6. Eliminates radicals so as to show strong activity of superoxide dismutase in body.
7. Improves the synthesis of marrow cells DNA, RNA and protein, accelerates splitting and propagation of marrow cells, and enhances blood producing function of marrow.
8. Reduces surface potential of cancer cells, inducts cancer cells gene to mutate again and initiate its fading program.
9. Kills tumor cells, but its mechanism remains unknown so far.
Ganoderma Lucidum is a rare germ in the traditional Chinese medicinal treasure house and it has been worshipped and deified for 3000 years by the oriental world. Zhongke Ganoderma Lucidum Spore is the best of the modern ganoderma lucidum products and has been widely used as BRM (biological regulating media), to help resist tumors and excellent effect has been achieved, which has brought the hope of life and recovery to those who suffer from cancer or other diseases.

Mycol Res 106:34–39, doi: 10.1017/S0953756201005007
Troskie AM, Vlok NM, Rautenbach M (2012) A novel 96-well gel-based assay for determining antifungal activity against filamentous fungi. J Microbiol Methods 91:551–558, doi:10.1016/j.mimet.2012.09.025
Turkoglu A, Duru ME, Mercan N, Kivrak I, Gezer K (2007) Antioxidant and antimicrobial activities of Laetiporus sulphureus (Bull.) Murrill. Food Chemistry 101:267–273, doi:10.1016/j.foodchem.2006.01.025
Wang X-C, Xi R-J, Li Y, Wang D-M, Yao Y-J (2012) The species identity of the widely cultivated Ganoderma, ‘G. lucidum’ (Ling-zhi), in China. PLoS ONE 7:e40857, doi:10.1371/journal.pone.0040857
Webster D, Taschereau P, Belland RJ, Sand C, Rennie RP (2008) Antifungal activity of medicinal plant extracts; preliminary screening studies. J Ethnopharmacology 115:140–146, doi:10.1016/j.jep.2007.09.014
Xu X, Zhu J (2011) Enhanced phenolic antioxidants production in submerged cultures of Inonotus obliquus in a ground corn stover medium. Biochem Eng J 58–59:103–109, doi:10.1016/j.bej.2011.09.003
Xu K, Liang X, Gao F, Zhong JJ, Liu JW (2010) Antimetastatic effect of ganoderic acid T in vitro through inhibition of cancer cell invasion. Process Biochem 45:1261–1267, doi:10.1016/j.procbio.2010.04.013
Ying J. MX, Ma Q., Zong Y. and Wen H.

REISHI Mushroom "The plant of immortality"
Updated: Dec 28, 2020
Ganoderma Lucidum (gan=shiny; derm=skin; lucidum=shining), Ling-Zhi or the more common name Reishi is the subject of my focus today. This unique looking mushroom has "roots" in Eastern medicine that dates back as far as 4000 years and was used for a wide variety of ailments. This mushroom has only been successfully commercially cultivated for about 20 years now, prior to that it was considered rare to find in the wild. In fact, in Japan it typically grows on plum trees and when 100,000 trees were checked only 1% of them were found to produce any Reishi mushrooms. Here in the United States you'll find them on Hemlock, Maple, Oak and fruit trees (mainly Cherry) but just like their Asian counter parts they can be a rare find. Here on the East coast the main fruiting season is from May to July.
Up until recently the rarity of Reishi also made it very expensive, although wild Reishi can still fetch between $80-$100 a pound (dried). That being said, even dried cultivated Reishi can still cost between $20-$30 a pound, even more for a particularly sought after strain. There are thought to be 6 different types of Reishi mushrooms, classified according to their color, and all are thought to have different healing properties (in truth the environment and growth stage is what has the most effect on the mushrooms properties). Blue, red, yellow white, black and purple Reishi are all said to have different flavors ranging from sour, to sweet, to even hot. The different colors are said to have different healing effects with the red typically being the most sought because it is regarded as the most potent and medicinal. I mostly use the red Reishi, primarily because that's the one that I found the most of this year.
I could go into talking about polysaccharides and triterpenes of Reishi, but I have just the very basic understanding of organic chemistry and would mostly be talking out of my ass like I had a deeper understanding. What I will say though is over the years more and more medical research has been conducted and proven that the folk medicine of thousands of years ago...isn't so much folk.

I
ignored them for four years until she died last year.
At present time, I have no intimate relationships. However, I decided to try ‘vigamaxx’ in the hopes of improving my sexual health in the future. I have noticed some very definite physical changes. I do have a great increased incidence of spontaneous erection which used to occur two to three times a week and now occurs twice or more in a day, especially upon waking. They are full, long lasting erections. This is a completely new event and a very encouraging to me for my future.
Lawerence Wang, Age 58
Ganoderma lucidum is one of the most beautiful mushrooms in the world. When very young its varnished surface is Chinese red, bright yellow, and white (see the bottom illustrations). Later the white and yellow shades disappear, but the resulting varnished, reddish to reddish brown surface is still quite beautiful and distinctive.
It is one of the extremely precious medicinal values of fungus. Chinese tradition health book recorded that Ganoderma can calm the nerves, strengthen to the lung and liver.
While Ganoderma lucidum is annual and does not actually grow more each year like some polypores, its fruiting body is quite tough and can last for months. This magical mushroom is also known as Reishi or Ling zhi which means "herb of spiritual potientcy"
Reishi had been added to the American Herbal Pharmacopoeia and Therapeutic Compendium. Once rare and expensive, this mushroom is now effectively cultivated and is readily available.
Modern research of Ganorderma lucidum started in the early 70's, many clinical reports revealed that Ganoderma has many beneficial effects to cure many kinds of diseases.
Some of its actions and properties include: Anti-allergin, antioxidant, analgesic, antifungal, anti inflammatory, anti tumor, antiviral antiparasitic, cardiovascular, antidiabetic, immunomodulating,hepatoprotective, hypotensive and hypertensive, kidney and nerve tonic, sexual potentiator. Inhibits platelett aggregations. Lowers blood pressure, cholesterol and blood sugar. Bronchitis prevention.

Ganoderma spore oil is a lipid extract of Ganoderma lucidum spores, which accounts for 20% to 35% of the total weight of the spores, and is rich in biologically active ingredients, such as triterpenoid ganoderic acid, unsaturated fatty acids, and steroids. Ganoderma spore oil has special physiological effects and has broad market prospects in the field of health products and medicine.
Ganoderma lucidum, also known as fungus Ganoderma lucidum, or Ganoderma lucidum, is a genus of Ganoderma lucidum in the family Basidiomycetes Polyporus. It is a mushroom parasitic on the roots of the oak and other broad-leaved trees. Umbrella-shaped, hard, woody, kidney-capped or semicircular, purple-brown with paint-like luster.
The ancient Orientals praised Ganoderma lucidum as a “magic panacea” that can be brought back to life and a “celestial herb” that cures all diseases. Modern scientific and clinical medical studies have proved that Ganoderma lucidum contains rich nutrients and biologically active substances, and it has a tonic and strong effect, it is the most ideal natural medicine and healthy food for human beings.
Ganoderma lucidum spore powder
The Ganoderma lucidum spore powder is the seed of Ganoderma lucidum. It is the extremely tiny egg-shaped reproductive cells ejected from Ganoderma lucidum pleats during the growth and maturity of Ganoderma lucidum. It is only 4-6 micrometers and is a living organism.
The spore powder contains all the active essences of Ganoderma lucidum. It contains 18 kinds of active amino acids, more than 20 kinds of polysaccharides, alkaloids, organic germanium, terpenoids, various vitamins, trace elements, and other pharmacologically active ingredients. Longevity and longevity can significantly improve the body’s immune function. It has antiviral, anticancer, tumor-suppressing, hypoglycemic, and other functions. Its medicinal value is much higher than that of Ganoderma lucidum fruiting body and mycelium.

Polysaccharides from G. Lucidum also affect increased concentrations of interleukin 2 (iL2), interleukina 6 (iL6) and interferon (iNF) and reduce the concentration of interleukin 1 (iL1), and tumor necrosis factors (TNF). G. Lucidum's extract shows inhibitor effects on the release of histamine from mastocytes, thereby contributing to alleviating allergy symptoms.
Substances from G. Lucidum have special effects on people infected with the HiV virus. Ganoderiol and ganodermanontriol inhibit the cytopathic effect of the HIV virus and slow its growth and progress in the body.

What is Ganoderma?
Ganoderma is probably the biggest mystery in the East that has been revealed after years of scientific research. Considered as Chinas natural treasure, ganoderma plantations have harvested its power and turned into the home of 100% organic Ganoderma.
In Cantonese, Reishi or Lingzhi refers to one of the types of Ganoderma Lucidum mushrooms. It keeps a dominant and honorable place in Asia, a rich region where it has been used as a powerful medicinal mushroom for over 4,000 years. Also known as the Miraculous King of Herbs, Ganoderma earned more popularity due to the advanced health benefits it brings. Its scientific name was derived from a Greek term that refers to bright and shiny skin. In Chinese, the word Lingzhi pertains to an herb known for spiritual potency and has been recognized as the mushroom of immortality. The mere origin of its name tells a lot about its role in the field of traditional and modern medicine.
Thanks to the modern developments in science and technology, ganoderma companies and their strategic partners have created 100% organic Ganoderma Lucidum capsules, Ganoderma Mycellium Healthy Beverages, Ganoderma Spore Powder, and skin care products. With these companies dedication to maximizing the potentials of Ganoderma, their research and development team has come up with an expanding line of clinically tested Ganoderma-based products.
The main processing plant used for manufacturing Ganoderma-based products submits to the highest GMP standards in the world. With an exclusive breakthrough called the Advanced Micro-Particle Technology, they have applied this discovery to boost the process of breaking spore cell walls. This fact guarantees these companies as the leading brands that produces products that were infused with 100% certified Ganoderma Lucidum.
Ganoderma's home may be China, but these companies and their growing team of skilled distributors are ready to share the wonders of Ganoderma with the rest of the world.

Heralded as the medicinal equal to Red Reishi (Ganoderma lucidum) for two millennia, wild Purple Reishi is rarer than ever due to deforestation, and still difficult to find high quality fruiting bodies through proper cultivation methods. Traditional Chinese medicine – Daoist herbalism in particular – has perceived this mushroom as a ‘supernatural medicine’, rare, sacred and potent.
Red Reishi boasts exponentially more scientific data, partly because it has proven easier to obtain, but research into Purple Reishi is ongoing and offering important medical revelations year after year. We have not yet arrived at a place where eastern and western medical traditions can seamlessly interface, as western medicine – although brilliant in many respects – is still in the juvenile stages of maturity and unable to verify or appreciate many of the subtle components of Asian medicine and the emphasis placed on Nature and its dynamic energetic forces.
From the historic perspective of Chinese medical herbalism, Purple Reishi has more than proven its value, not only as a rejuvenating medicine that can strengthen the joints and sinews of the body, but as a protector from infectious diseases and as a support for the emotional mind and human spirit.
Anima of the forest – subject of folklore; Purple Reishi emits an aura of magic and mystery, and perhaps it always will. We can never understand everything there is to know about such complex organisms, but we can mindfully and conscientiously ally ourselves to them, and flourish all the better for it.
Comparison of Polysaccharides from G. sinense & G. lucidum
Triterpenoids from G. sinense & G. lucidum
Unique Terpenoids in G. sinense & Their Properties
Two Novel Lanostane Triterpenes from G. sinense
Ganoderma sinense in the Treatment of Arthritis
Ganoderma sinense as Adjuvant in Chemo & Radiation Treatment
Immune-Modulating Activity of G. sinense Fruiting Bodies

High Quality Ganoderma Lucidum P. E. Reishi P. E. Reishi Mushroom P. E. Polysaccharide Extract
GanoHerb has different kinds of organic Ganoderma extract powder for you to choose. We have water extraction, alcohol extraction and mix extraction ganoderma extract powder. Those extract’s polysaccharides range from 5-40%, triterpene range from 0-12%, and you can also tell us your needs, we can manufacture according to your requirements.
GanoHerb use single effect, double effect, and ball-type vacuum concentration, compared with traditional concentration, it is more efficient. It can protect the active ingredients at the greatest extent with the advantage of concentrated time and low temperature. Adopt spray drying or microwave vacuum drying method. Spray drying method in which the drying time is shorter, products are uniform fine, with good mobility and high solubility. While microwave vacuum drying method with low drying temperature , high efficiency ,which can reduce the damage of the active ingredient, and improve the quality of heat-sensitive products.
GanoHerb has following extracts in stock：
Ganoderma Extract A1: Polysacchride＞10 %, triterpene＞8%,
Ganoderma Extract A2: Polysacchride＞15%,
Ganoderma ExtractA3: Polysacchride＞25 %,
Ganoderma Extract A4: Polysacchride＞5%,
[Source] Ganoderma lucidum extracts are extracted from the top-grade Ganoderma, via advance modern technology.
[Product Property] Powder between light yellow and brown, with a special fragrance.
[Product Content] Crude Polysaccharides 5-40 %
Total Triterpenes 0-12%
[Testing Method] Ultraviolet-visible Spectrophotometry (UV)
[Effective Component] Crude Polysaccharides, total Triterpenes.
[Medical Functions] It can help to nourish user’s vitality and relieve malaise, cough, asthma, palpitation, and anorexia.
[Specification] 80 mesh
[Storage] Sealed and placed in a cool and dry place
[Shelf-life] 2 year

2005;46(5):585-96.
Yue GG, Fung KP, Tse GM, Leung PC, Lau CB. Comparative studies of various ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitro. J Altern Complement Med. 2006 Oct;12(8):777-89.

The six reishi colors are:
- Akashiba ( red )
- Aoshiba ( blue)
- Kishiba ( yellow)
- Kuroshiba ( black)
- Murasakishiba ( purple)
- Shiroshiba ( white)
It is believed to be the oldest medicinal mushroom and is said to help build the immune system, maintain one’s physical shape, and promote longevity. Reishi is commercially grown in China, Japan, Korea, North America, and Taiwan. In order to decide whether or not the Ganoderma or Reishi Mushroom is Hype or a Healing Miracle, one must take a look at the health benefits, side effects, case studies performed, and personal testimonies.
Chinese Scientists Research Reishi - Lindzhi - Ganoderma
Ganoderma Lucidum Benefits
Like many alternative herbal medicines, this magical mushroom works with the body to promote one’s natural immune system, helps the body to balance and harmonize itself, which in turn treats a wide range of health problems. Ganoderma or reishi consists of the “anti” properties of being anti-allergen, anti-fungal, anti-inflammatory, anti-oxidant, anti-parasitic, anti-tumoral, anti-viral and analgesic. Having an increased level of antioxidant compounds within one’s body is believed to help protect against aging and diseases.
Ganoderma is often used as a cancer treatment by assisting in eliminating impurities and toxins to cleanse the body and help make the immune system stronger. It stimulates cell regeneration by promoting the detoxification of the liver to improve its functions. In addition to possessing anti-cancer agents of Germanium and polysaccharides, that helps to produce anti-tumor effectiveness, protect against degeneration of skin cells while reducing the appearance of aging.
Reishi or Ganoderma has 23,500 I.Us and is considered to be one of the most potent antioxidants known. These antioxidants neutralize the oxidant effect of free radicals and assist in promoting normal metabolism and normal cellular respiration. Having such qualities enables it to be versatile with many uses such as the treatment of allergies, altitude sickness, chemotherapy support, diabetes, fatigue, hepatitis, hypertension, high triglycerides, kidney cleanser, nerve tonic, and sexual enhancer.

Glossy TaiwanTCM is a powdered glossy glossy gourd ( Ganoderma lucidum ), which meets the strictest standards of the TCM. Powder is prepared by grinding and specially modifying selected portions of natural fruit-trees from pure mountain environment of central Taiwan.
It does not contain artificial additives or preservatives. The taste of the powder is naturally bitter, later sweet. Capsules are gelatinous. Capsule weight 420mg +/- 5%. Recipe and Material: SunGertain BIO-RD, Taiwan
The quality of the product is a key place and way of growing the puppies. Environmental cleanliness is especially important for fungi. Many studies have demonstrated the ability of fungi, even in a relatively clean environment, to accumulate a number of heavy metals and radionuclides many times above their concentration in the environment. Central Taiwan, where glossy shiny TaiwanTCM is grown, is an extensive area of the mountain ranging from more than 4000m above sea level with a minimum concentration of impurities in the environment.
Another problem with the fungal material is the genetic degeneration, which the mushrooms in cultivation are gradually subject to and which leads to the reduction of efficacy. This can be prevented by chemical and genetic control of the fungal material. In this area, Taiwan again has an unquestionable advantage - it is no coincidence that the glossy gloss genome was first deciphered in Taiwan.
The glans of the glossy gloss are tough. They can only be consumed in powder, liquid or tablet form. The liquid form includes tea and extract. Glossy Taiwan TCM is available in the form of capsule powder. They are used directly and drunk with lukewarm water. The powder can be consumed without the capsules - its bitter taste is pleasant if we get used to it. This is done by opening the capsule, pour the powder into a glass of lukewarm water and stir in the spoon. We get a healthy drink whose bitterness resembles bitter coffee.
Ordinary dosing 3 times a day 1-3 capsules in the morning, drink with lukewarm water (or dissolve the powder in lukewarm water). The TC recommends a short warm up exercise after ingestion. Even at lower doses, however, the glossy glass of TaiwanTCM has significant effects. With a precautionary dose of 1 capsule / day, one package lasts for half a year.

In: Boddy L, Frankland JC, van West P (eds) British Mycological Society Symposia Series, vol 28. Academic Press, pp 63–78. doi:10.1016/S0275-0287(08)80006-9
McCormick MA, Grand LF, Post JB, Cubeta MA (2013) Phylogenetic and phenotypic characterization of Fomes fasciatus and Fomes fomentarius in the United States. Mycologia 105:1524–1534, doi:10.3852/12-336
Meng L-Z, Lin B-Q, Wang B, Feng K, Hu D-J, Wang L-Y, Cheong K-L, Zhao J Li S-P (2013) Mycelia extracts of fungal strains isolated from Cordyceps sinensis differently enhance the function of RAW 264.7 macrophages J Ethnopharm 148:818–825. doi:10.1016/j.jep.2013.05.017
Molitoris HP (2005) Fungi: companions of man in good and evil. Int J Med Mushrooms 7:49–73, doi:10.1615/IntJMedMushr.v7.i12.70
Neifar M, Kamoun A, Jaouani A, Ellouze-Ghorbel R, Ellouze-Chaabouni S (2011) Application of asymetrical and hoke designs for optimization of laccase production by the white-rot fungus Fomes fomentarius in solid-state fermentation. Enzyme Res 2011:368525–368525, doi:10.4061/2011/368525
Ota Y, Hattori T, Banik MT, Hagedorn G, Sotome K, Tokuda S, Abe Y (2009) The genus Laetiporus (Basidiomycota, Polyporales) in East Asia. Mycol Res 113:1283–1300, doi:10.1016/j.mycres.2009.08.014
Paterson RRM (2006) Ganoderma - A therapeutic fungal biofactory.

Am J Exp Agric 2(1):47–73, doi:10.9734/AJEA/2012/492
Lemieszek MK, Langner E, Kaczor J, Kandefer-Szerszen M, Sanecka B, Mazurkiewicz W, Rzeski W (2009) Anticancer effect of fraction isolated from medicinal birch polypore mushroom, Piptoporus betulinus (Bull.: Fr.) P. Karst. (Aphyllophoromycetideae): in vitro studies. Int J Med Mushrooms 11:351–364, doi:10.1615/IntJMedMushr.v11.i4.20
Liu X-T, Winkler AL, Schwan WR, Volk TJ, Rott M, Monte A (2010) Antibacterial compounds from mushrooms II: lanostane triterpenoids and an ergostane steroid with activity against Bacillus cereus isolated from Fomitopsis pinicola. Planta Med 76:464–466, doi:10.1055/s-0029-1186227
Liu D, Gong J, Dai W, Kang X, Huang Z, Zhang H-M, Liu W, Liu L, Ma J, Xia Z, Chen Y, Chen Y, Wang D, Ni P, Guo A-Y Xiong X (2012) The genome of Ganderma lucidum provides insights into triterpene biosynthesis and wood degradation. PLoS ONE 7:e36146, doi:10.1371/journal.pone.0036146
Lo H-C, Wasser SP (2011) Medicinal mushrooms for glycemic control in diabetes mellitus: History, current status, future perspectives, and unsolved problems (review). Int J Med Mushrooms 13:401–426, doi:10.1615/IntJMedMushr.v13.i5.10
Lv GP, Zhao J, Duan JA, Tang YP, Li SP (2012) Comparison of sterols and fatty acids in two species of Ganoderma. Chem Cent J 6:10, doi:10.1186/1752-153x-6-10
Magan N (2008) Chapter 4 Ecophysiology: Impact of environment on growth, synthesis of compatible solutes and enzyme production.

Whereas wild ones are dark in colour, the cultivated Japanese varieties are grown in low-light conditions and have pale flesh and skin.
This mushroom fruits in cold conditions. Fruiting bodies are small, but delicious. This mushroom has been eaten for centuries in parts of Asia. It grows naturally on wood and can be cultivated on sawdust.
Lentinus edodes, the Shiitake mushroom, is the most important cultivated mushroom in Japan. It is grown on logs of Fagaceae trees (eg: Oaks) and various other trees. The shiitake mushroom is said to possess many health benefits, including the presence of many polysaccharides and polysaccharide-protein complexes that have been isolated and utilised for therapeutic purposes (it has been reported as promoting health due to immunity stimulating properties against cancer, viral infection and high cholesterol). This mushroom is usually sold fresh or dried. There is potential for commercial shiitake mushroom cultivation, although many markets have high quality standards that must be met.
Several species of this genus are edible and have the potential for cultivation commercially. Pleurotus ostreatus is perhaps the most commonly cultivated species, known as the oyster mushroom, due to its appearance. The oyster mushroom naturally grows on dead wood, but can be cultivated on any cellulose material. Wood shavings, cellulose fibre, and waste hulls from agriculture are commonly used. This mushroom can even be cultivated on toilet rolls!
This species of mushroom, sometimes known as the ‘Garden Giant’ has been grown commercially in Germany, and grows wild in parts of Europe. It is cheap and easy to grow, but yields are variable.
It is not generally suited to commercial production, but is well suited to outdoor culture in the home garden. Indoor fruitings are possible but the King Stropharia requires an unsterile casing to stimulate mushroom development and is slow to fruit.
The edible Straw Mushroom originates from the tropics and sub-tropics, and has been cultivated and eaten for centuries in China and other Asian countries. This mushroom is traditionally cultivated on fermented rice straw. Due to the nature of traditional cultivation, yields have typically been low and variable. Modern cultivation practices utilising industrial waste from cotton processing have allowed increased yields and further development of the Straw Mushroom industry.

Using PNW Mushrooms in Skin Care
Fruiting bodies protrude from their hosts throughout our forests, the Ganodermas are a sight to behold and entirely hard to ignore. Ganoderma in itself means “shiny skin” of course referring to the varnished crust on many of the species in this genus, but how can we not apply this to our own, human skin. Following is research that has been done on Ganoderma lucidum, Ganoderma tsugae, and Tremella fuciformis and their uses in skin care. I am postulating that we can use out Northwest analogs, Ganoderma applanatum, Ganoderma oregonense, and Tremella mesenterica, the same way.
Sacchachitin and Polysaccharides for Wound healing
There is a product made, called Sacchachitin that is used as a wound dressing. It is made from the pulp of the Ganoderma fruiting body and when used, significantly speeds up the healing process of skin wounds. (Hung 2004) This product of course is not manufacturable by the general public, yet it is easy enough to chop up the Ganoderma into small pieces, place in a blender with a little water and create a pulp that is then simmered for about an hour. The simmering is not necessary for a styptic effect, but you want to extract the polysaccharides to see anti inflammatory, antioxidant and increased healing time effects. Speed of wound healing was also observed when Ganoderma polysaccharides were applied to the wounds of diabetic mice. It was observed that the polysaccharides accelerated the wound healing my inhibition of mitochondrial oxidative stress and improved wound angiogenesis (Tie 2012).
Healing from UVB damage
Tremella fuciformis has been used in skin care in Asia for decades, yet there is little research on our local species of Tremella, Tremella mesenterica. The polysaccharide content is comparable and so I am using the research and traditional uses of Tremella fuciformis as being analogous to the potential uses of Tremella mesenterica. Tremella is known to be a potent antioxidant and anti-inflammatory fungus. The Tremella polysaccharide extract was tested on hydrogen peroxide-induced injury of human skin fibroblasts.

They have essential amino acids, fatty acids, B vitamins, vitamins E and K, minerals, and trace elements.
They also have similar bioactive substances, including beta-glucans and enzymes.
The benefits are similar in that they can both support the health of the heart, kidneys, liver, and lungs, and both support healthy aging and the regulation of your sleep cycle.
Both have anti-inflammatory and immune-modulating benefits.
The differences are primarily in the research that’s been done on both species so far.
For example, in animal studies, the cordyceps sinesis species has been found to reduce oxidative stress and improve exercise endurance.
In human studies, there is research on exercise performance and wellness in older people, and in sedentary adults, this species of cordyceps has been linked to energy metabolism.
The militaris species of the fungus has been researched for supporting high-intensity exercise in younger people and cell-mediated immunity.
The cordyceps sinesis species is rare and expensive in its wild form, but the cultivated form is easier to access and less expensive.
Overall, you could take either species of cordyceps and get similar benefits. Some supplements on the market combine both species into one product.
Cordyceps militaris is sometimes called the cultivated alternative, but both species can be similarly cultivated.
Cordyceps sinesis is the most studied species, with militaris coming in behind it.
Traditional Chinese Medicine Uses
In Traditional Chinese Medicine (TCM), this mushroom is called Chinese caterpillar fungus.
One of the uses of TCM is treating chronic kidney disease.
In traditional Eastern medicine, along with helping kidney function, cordyceps is also used for heart health, and it’s long been used to improve energy, vitality, and stamina.
Why Are So Many People Taking Cordyceps?

The basidiocarp, mycelia and spores of Ganoderma lucidum contain approximately 400 different bioactive compounds, which mainly include triterpenoids, polysaccharides, nucleotides, sterols, steroids, fatty acids, proteins/peptides and trace elements which has been reported to have a number of pharmacological effects including immunomodulation, anti-atherosclerotic, anti-inflammatory, analgesic, chemo preventive, antitumor, chemo and radio protective, sleep promoting, antibacterial, antiviral (including anti HIV), hypolipidemic, anti-fibrotic, hepatoprotective, anti-diabetic, anti-androgenic, anti-angiogenic, anti herpetic, antioxidative and radical-scavenging, anti aging, hypoglycemic, estrogenic activity and anti-ulcer properties. Ganoderma lucidum has now become recognized as an alternative adjuvant in the treatment of leukemia, carcinoma, hepatitis and diabetes.
The macrofungus is very rare in nature rather not sufficient for commercial exploitation for vital therapeutic emergencies, therefore, the cultivation on solid substrates, stationary liquid medium or by submerged cultivation has become an essential aspect to meet the driving force towards the increasing demands in the international market. Present review focuses on the pharmacological aspects, cultivation methods and bioactive metabolites playing a significant role in various therapeutic applications.
Research and Development Centre, Bisen Biotech and Biopharma Pvt. Ltd., Biotech Research Park, M-7, Laxmipuram, Transport Nagar, Gwalior- 474010 (M.P.) India. email@example.com.
Taking care of the whole you includes your heart.
The same healthy basics that reduce your risk of other diseases also help to keep your heart strong.
* A healthy heart starts with eating right. Heart-healthy foods like fruits, vegetables, healthy proteins (such as fish, beans, chicken, nuts and low-fat dairy), and whole grains will help keep your heart and blood vessels in good shape.
* Drinking too much alcohol can raise your total cholesterol levels and your blood pressure. Limit alcohol to no more than 1 drink a day for women or 2 drinks a day for men.
* Brisk walking, swimming, or cycling are especially good for the heart, but choose any activity you enjoy for a fun exercise routine. Start at your comfort level, and build up gradually.

It was listed among the six primary types of Ganoderma in the seminal pharmacopoeia of Chinese medicine; the Shennong Ben Cao Jing. In this text it was regarded as one of truly superior medicines and long term use was understood to “make the body light, prevent senility and prolong life so as to make one an immortal.”
It was prescribed to fortify the circulation of qi within the body, it was deeply restorative and could promote radiant vitality. It was commonly used to treat conditions relating to the kidneys and the sense of hearing, it strengthened the bones, joints and connective tissue, and was understood to protect the user on a subtle, spiritual level.
Purple Reishi was understood throughout the ages to be an exceptional aid in the replenishment of spent vitality and deep rejuvenation of the body and mind after exhaustion, burnout, childbirth, sickness and injury. Our energetic storehouse of vitality is known as ‘Jing‘ in Chinese medicine, and this species of Reishi is ranked at the very top of natural medicines that help to restore this vital essence.
It is a tonic to the kidneys, liver and heart, and was traditionally used as a support for meditation and spiritual practice due to the subtle yet profound effect it was believed to have on stabilising the emotional mind. Purple Reishi is one of the genuine treasures of Taoist herbal medicine, and its rarity only magnified its value.
How is it Different from Red Reishi?
As already mentioned the two species are so similar that they were often used interchangeably or one was substituted in the absence of the other. However, as we have seen there are differences such as the overall profile of active constituents, the taste and obviously the colour/appearance.
While both of these majestic organisms are exceptional, well-rounded tonics, Purple Reishi seems to emphasise a deeper restorative quality than its crimson relative. Throughout history G. sinense was always used in favour of G. lucidum in cases of arthritis, weak bones/joints and damage to cartilage and other connective tissue. It was employed as a preventative of these conditions as well as a treatment for them.
In cases of exhaustion and burnout both species were often used, although again, the deeply regenerative qualities of G. sinense would be preferred, if it was available.

Mycol Res 112:231–240, doi:10.1016/j.mycres.2007.08.018
Geiger M, Gibbons J, West T, Hughes SR, Gibbons W (2012) Evaluation of UV-C mutagenized Scheffersomyces stipitis strains for ethanol production. J Lab Automat 17:417–424, doi:10.1177/2211068212452873
Grienke U, Zöll M, Peintner U, Rollinger JM (2014) European medicinal polypores – A modern view on traditional uses. J Ethnopharmacol 154(3):564–583, doi:10.1016/j.jep.2014.04.030
Guler P, Akata I, Kutluer F (2009) Antifungal activities of Fomitopsis pinicola (Sw.:Fr) Karst and Lactarius vellereus (Pers.) Fr. Afr J Biotechnol 8:3811–3813, doi:10.5897/AJB09.719
Hallenberg N, Larsson E (1991) Differences in cultural characters and electrophoretic patterns among sibling species in four different species complexes (Corticiaceae, Basidiomycetes). Mycologia 83(2):131–141
Hobbs C (1995) Medicinal mushrooms: An exploration of tradition, healing and culture. Botanica Press, Santa Cruz
Högberg N, Holdenrieder O, Stenlid J (1999) Population structure of the wood decay fungus Fomitopsis pinicola. Heredity 83:354–360, doi:10.1046/j.1365-2540.1999.00597.x
Hseu RS, Wang HH, Wang HF, Moncalvo JM (1996) Differentiation and grouping of isolates of the Ganoderma lucidum complex by random amplified polymorphic DNA-PCR compared with grouping on the basis of internal transcribed spacer sequences.

Name: anoderma Lucidum Spore Powder
Origin : China
Grade : Good
Weight : 500 grams
Usage: 3-5 grams each time, once in the morning and once in the afternoon. Pour in warm water and drink it.
Sealed packaging OR Refrigerator freezer room. Dry and no direct sunshine
Spores are released from Ganoderma Lucidum when maturity. They are very tiny, which cannot be seen with our naked eyes, only be seen through a microscope.
Ganoderma Lucidum Spores powder are formed by numerous spores. The Ganoderma Lucidum spore can be up to 75 times more therapeutic than the whole original Ganoderma Lucidum of the same weight.
The essential nutrients of Ganoderma Lucidum is in its spore. Ganoderma Lucidum itself has been used in China for many centuries for its various healing properties. It is well known for its function in strengthening the body immune system. With better body immune system, it helps to support in the management of chemotherapy and radiatherapy treatment eg. helps to ease the side effects resulted from the treatment. Continuously taking, Ganoderma Lucidum spore powder helps to improve quality of our whole body system ie. in promoting the blood circulation,digestion, metabolism and bowel regularity, reducing fatigue, enhancing alertness, improving sleeping,protecting liver, etc.
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N.B.: If the seller provides the "Longer Protection" service on this product, you may ask for refund up to 15 days after order completion.

- Growing its Ganoderma using the natural log method so it can manufacture Ganoderma spores which are 17 times more powerful than the Ganoderma Lucidum mushroom itself.
- Offering more friendly American products such as brewed coffee and less sugar.
- Creating a more generous compensation plan that puts more money into all distributors pockets, including the oft-forgotten part-timer.
- Provides a more dynamic, comprehensive, and accessible training system
- Developed a better replicated web site system.

Chem Nat Compd 43(6):687–688, doi:10.1007/s10600-007-0229-4
Banik MT, Lindner DL, Ota Y, Hattori T (2010) Relationships among North American and Japanese Laetiporus isolates inferred from molecular phylogenetics and single-spore incompatibility reactions. Mycologia 102(4):911–917, doi:10.3852/09-044
Banik MT, Lindner DL, Ortiz-Santana B, Lodge DJ (2012) A new species of Laetiporus from the Caribbean basin. Kurtziana 37:15–21
Bode HB, Bethe B, Hofs R, Zeeck A (2002) Big effects from small changes: possible ways to explore nature's chemical diversity. Chembiochem 3(7):619–627, doi:10.1002/1439-7633(20020703)3:7<619::aid-cbic619>3.0.co;2-9
Breheret S, Talou T, Rapior S, Bessiere JM (1997) Volatile compounds: A useful tool for the chemotaxonomy of Basidiomycetes. Cryptogam Mycol 18:111–114
Chang STMK (2000) Ganoderma lucidum-Paramount among medicinal mushrooms. Discov Innovat 12:97–101
Chang ST, Wasser SP (2012) The role of culinary-medicinal mushrooms on human welfare with a pyramid model for human health. Int J Med Mushrooms 14:95–134, doi:10.1615/IntJMedMushr.v14.i2.10
Chen W, Zhao Z, Chen S-F, Li Y-Q (2008) Optimization for the production of exopolysaccharide from Fomes fomentarius in submerged culture and its antitumor effect in vitro. Bioresource Technol 99:3187–3194, doi:10.1016/j.biortech.2007.05.049
Chen W, Zhao Z, Li Y (2011) Simultaneous increase of mycelial biomass and intracellular polysaccharide from Fomes fomentarius and its biological function of gastric cancer intervention.

Ganoderma or Reishi Mushroom – Hype or a Healing Miracle?
For over a year now I’ve seen the words ganoderma or reishi and decided to perform my own research to see if the Ganoderma or Reishi Mushroom was Hype or a Healing Miracle like it is being advertised. If you are like me, MLMs come by your way quite often and many of them you should not pay a dime for a dozen. Being somewhat skeptical yet an inquisitive individual, I’m not easily impressed by the words, “healing miracle." After all these words have been used over the years to sell everything from snake oil to placebo pills only to take money from trusting individuals. With that said, please allow me to share with you the information I’ve found.
What is Ganoderma?
The Ganoderma mushroom is not recommended to be used for cooking, however, for over 2,000 years it has been used in Chinese traditional medicine (TCM) for the medicinal purposes of promoting health and longevity. Ganoderma Lucidum is sometimes referred to by the Chinese as the “Miraculous King of Herbs” and is highly regarded for its medicinal properties that assist in helping to improve the body’s healing abilities.
The ancient Taoists believed this mushroom to be the “elixir of eternal youth.” Ganoderma, commonly known as reishi is a hard bitter mushroom that is said to relieve fatigue, lower high blood pressure, reduce cholesterol, reduce inflammation, while building stamina, and improving the immune system.
Japanese and Chinese emperors for years have drunk herbal tea and mushroom concoctions to achieve virility and vitality. Because it was rare and very expensive the commoners did not get to partake of this natural herb until later years when growth and cultivating became easier. This mushroom is recorded in the 2,000 year old Chinese medical text and is known for curing cancers and various diseases such as arthritis, hypertension, and liver disorders.
This medicinal fungi is commonly know by many names such as Ling zhi (meaning the herb of spiritual potency) Mannentake, and Reishi. Ganoderma is a folk medicine that has been in existence since ancient times and can be found in six different colors of hues with red being the most commonly used.

* There are over 30 large human trials conducted in China alone, in addition to many in vitro, and in vivo studies.
Nuliv Science’s proprietary fermentation technology uses specific carbohydrates, soybean extracts, and a special blend of trace elements, in addition, other proprietary ingredients as a growth medium. Additionally, specific temperature and Ph parameters are maintained through various stages of the fermentation process to consistently produce the highest quality Cordyceps.
Our PhytoMonitor™ Quality Assurance System guarantees CordycepsPrime™ to meet stringent quality standards.
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Maitake mushroom is a fungi from the Grifolafrondosa species. They are also known as Sheep’s Head, Hen-of-the-Woods, Ram’s Head, and other names. Maitake is the mushroom’s Japanese name. It means “dancing mushroom.” This mushroom grows in clusters at the base of trees, especially oak trees. Grifolafrondosa is used in both Japanese and traditional Chinese medicine as a powerful medicine that may balance body systems and boost the immune system.* This mushroom is also frequently eaten because of its pleasing flavor and texture, especially in Japan.
Maitake mushrooms are sold in health food stores around the world and online at websites that sell herbs, especially Chinese or Asian herbs. They typically grow at the base of the same trees for years, and they can be very large when they are full grown. Maitake can grow to 50 pounds in Japan. Maitake mushrooms have many minerals such as potassium, magnesium, and calcium. They are also full of fibers and amino acids and various vitamins such as D1, B2, and niacin.
Reishi mushroom is a part of the Ganoderma lucidum family.
Regarded as one of the most vital herbal medicines in China for centuries, Reishi mushrooms are used for many purposes ranging from immune-related concerns to promoting proper energy levels. It is also used as a sports enhancer in parts of China. The active ingredient in the fungus is triterpenoids. Reishi is generally not eaten whole or raw. It is usually made into tea or taken as a powder mixed into another drink.
Coriolus Mushroom (Coriolus versicolor) 30% is a fungus that has been used for many centuries in Traditional Chinese Medicine.

Today, let us focus on two medicinal mushrooms – the Reishi and the Chaga mushrooms, and talk about their health benefits so that you can decide and act on that knowledge if you’re in the middle of deciding whether to supplement with them or not.
Reishi (Ganoderma lucidum)
It’s a visually attractive mushroom with shiny skin and woody texture. Sometimes, it may even seem as if it is a varnished work of art to those who would see it the first time.
The mushroom typically grows on plum, oak and other hardwood trees, to name some. Their species are of sizes ranging between 2 and 20 centimeters and have a kidney-shaped cap.
What are the health benefits of Reishi? There have been extensive studies of the herb, especially among the Japanese and Chinese Reishi, and these researches found out that Reishi, the spirit herb, offers multiple benefits for the body.
Reishi improves the mind, body and spirit, and so its title “spirit herb.” While it sounds like foreign magic of some sort, this herb is actually also known to give its users a “longer life.”
Basically, it has bioactive compounds, including polysaccharides, such as triterpene, which has anti-tumorigenic, hypolipidemic and anti-inflammatory properties. The acid called Ganoderic is the main active triterpene that’s known to fight cancer – and it’s in the mushroom.
In addition, it has also shown to help in reducing phlegm, toning the blood, promoting better sleep and strengthening visceral organs.
Another benefit is on athletic performance, as it helps in enhancing blood oxygenation and preventing altitude sickness (for mountain climbers).
For heart health, Reishi may help in lowering bad cholesterol levels, and reducing plasma and blood viscosity, especially among patients suffering from high cholesterol and high blood pressure.
It is also proven to aid in immune system enhancement, as it works potently against sarcoma and it aids in the prevention and treatment of various ailments.
To discuss its ailment fighting and immune system boosting properties further, Reishi is also known for its high content of complex sugars, which are essential for immunity especially in terms of increasing the DNA and RNA in the bone marrow, where immune cells are born and its stimulating properties on antibody production.

These include adenosine, said to have an analgesic effect, R,S-ganodermic and ganasterone that have an antihepatoxic effect, and glucans and polysaccharides that are responsible for the anti-inflammatory and antitumor properties of G. lucidum.
Something else to keep in mind is that all these experiments were done in cell lines, mice, rats and hamsters. So far no large scale unbiased human trials have yet been performed, and the FDA does not yet approve use of Reishi as medical treatment. In order to gain FDA approval, purified compounds from G. lucidum would have to go through an intensive amount of screening in cell lines and animals; much of this pre-clinical testing has already been performed. The next step would be a phase one clinical trial, which assesses the potential drug's safety. Healthy volunteers are paid to take the drug for a certain amount of time, and the compound is studied for its absorption into the body, its metabolism, and its excretion. Once the potential drug passes phase one, which can take up to several months, it moves on to phase two. In phase two, several hundred patients participate in what is called a double blind clinical trial, in which both the patient and the physician are unaware of whether the patient is receiving the potential drug or a placebo . Phase two can last from several months up to several years. If the potential drug is proven effective after phase two, it moves to phase three. Phase three also consists of blind clinical trials, but on a much larger scale. This phase is used to understand the drug's effectiveness, benefits, and the range of possible adverse reactions. Without a doubt, G. lucidum and its researchers have a long road ahead of them before they can prove the mushrooms healing powers.
I hoped you enjoyed learning about Ganoderma lucidum, its relatives and potential uses. Although these species of fungi can produce beautiful fruiting bodies, who would have expected them to hold so many potentially useful chemicals?
This month's co-author is Kathleen Engelbrecht, one of my students in Mycology, Medical Mycology, and Advanced Mycology. She's working on an interesting project looking for potentially useful compounds from fungi.
If you have anything to add, or if you have corrections, comments, or recommendations for future FotM's (or maybe you'd like to be co-author of a FotM?

Maintaining quality and purity, MIGU Adaptogen Bio-tech Co., Ltd now introduces fungus extract powders of Ganoderma Lucidum Extract, Cordyceps Sinensis Extract and Agaricus Blazei Extract.
Xi'an, China, March 3, 2018 – There are several kinds of high quality fungus extract powders that can have enormous health benefits for the mankind. China based MIGU Adaptogen Bio-tech Co., Ltd specializes in extracting powder from different herbs that have great medicinal value. These fungus extracts can cure several types of diseases and can also boost the immunity and vitality of humans in a natural manner.
The company has introduced the Ganoderma Lucidum Extract, which is extracted from the fruiting part of Reishi mushroom. MIGU Adaptogen Bio-tech Co., Ltd cultivates Reishi mushroom in its own farmland and which is far better in quality than the wild Reishi mushroom. They pick the mushroom at the proper time and dry it properly to maintain its potency. According to some research, the Reishi mushroom extract comes with cancer healing properties, and MIGU Adaptogen Bio-tech Co., Ltd supplies the best quality extract for cancer patients around the world. The medicinal agents of the extract called phytonutrients works wonder in healing cancer patients.
Another important addition is the Cordyceps Sinensis Extract that comes with amazing anti-aging and anti-inflammatory properties. The extract can significantly improve the learning ability and the memory functions. This fungus is mainly of parasitic nature, and MIGU Adaptogen Bio-tech Co., Ltd cultivates it industrially for its large scale production. This extract also has an anti-tumor potency to cure tumors naturally, and can be recommended to cancer patients who are undergoing chemotherapy. Besides, the cancer treatment, the extract is a powerful anti-oxidant and is also very useful in diabetes for controlling the blood sugar level.
MIGU Adaptogen Bio-tech Co., Ltd also brings the Agaricus Blazei Extract, which is extracted from the fruiting body. This is a new medicinal mushroom that contains beta glucan that stimulate the natural cells, which are the vital part of our immune system. It is believed that these polysaccharides are potent enough to promote the cellular health. Besides, it also has a strong anti-tumor effect and is beneficial for cancer patients after the chemotherapy.

2007) and also for the production of bioactive secondary metabolites (Lv et al. 2012; Sørensen and Giese 2013). We therefore recommend that strain selection and preliminary bioactivity testing should become common practice for all studies focusing on constituents and biological effects of medicinal polypores. Fungal strain selection is routinely applied for a wide range of species used for food (Chiu et al. 1999; Liu et al. 2012; Terashima et al. 2002), biotechnology (Geiger et al. 2012), and biocontrol (Cui et al. 2014).
All strains used in this study were isolated from those fruit bodies which were later used for extraction and bioactivity testing. Their colony growth rates were tested under standard conditions in order to investigate strain-specific properties without the influence of different substrates or environmental factors. When considering only strains of F. fomentarius belonging to the same lineage, the quantity and quality of secondary metabolites produced by temperate strains showed clear differences. One strain isolated from Fagus (IB20130019) exhibited significantly different growth characteristics compared to all other strains isolated from Picea: It was growing significantly slower and had a lower optimal temperature. This strain was also extremely differing in metabolite production and bioactivity.
Also F. pinicola strains isolated from Picea had different growth rates and optimum temperatures than strains isolated from other substrates (Abies, Alnus, or Larix) even when originating from the same geographical area. Bioactivity tests confirmed these strain-specific differences, because all strains from other substrates had a stronger antifungal activity than strains isolated from Picea. This suggests that substrate is a strong trigger for or may influence metabolite production. In any case, the strain-specific differences remained stable under standardized conditions (in vitro). Additional studies comparing extracts from wild-grown fruit bodies with extracts from fruit bodies cultivated in vitro (under standard conditions) from the same strain will further elucidate the influence of strain characteristics on the metabolite profile and the respective bioactivities. Testing different environmental parameter and substrates is a suitable method to pre-select strains of medicinal polypores and their growth conditions for upscaling to increase the biosynthesis of bioactive secondary metabolites.

Ganoderma Lucidum mushroom tea is an indispensable partof traditional Chinese medicine- and as such is present in treating many diseases.
However, preparing tea in the traditional way carries with it several problems. Traditional preparation loses many active substances. Also, in order to achieve a satisfactory concentration of active substances, tea must be cooked for at least an hour!
To avoid these difficulties and make it easier for our customers to use tea from this mushroom, we have developed ImuninTea!
Imunin tea allows for quick cleaning in 5 minutes- as with regular teas. Imunin tea allows you to ingest far more active substances than traditionally prepared tea, and retains all the beneficial effects of this kind of tea without additives or artificial ingredients.
Toss with boiling water and wait 5 minutes, consumed as regular tea, by choice, with honey!
The substances from the Ganoderma Lucidum mushroom have numerous effects on human health. It's fair to say that G. Lucidum is one of the most potent natural means of strengthening and improving health. The substances in this fungus primarily act on the immune system, support its normal functions, improve them and strengthen them in case of infection defenses, while normalizing it in case of allergies. By regularly ingesting substances from G. Lucidum, we support the immune system in the fight against infections, cancers, allergies and inflammation. In people with autoimmune diseases, it soothes and stables the condition.
Substances from Mr. Lucidum have a particular effect on people infected with HIV, slowing the progression of the virus through the body.
Studies have shown that polysaccharides from Ganoderm Lucidum modulate immune functions in vitro and vivo.
The immunomodulating effects shown by G. Lucidum's polysaccharides are extensive, including the functions of antigen-presenting cells, mononuclear fagocitic system, humorous immunity and cellular immunity. Components from G. Lucidum also showed an impact on gene expression in monocytes, a type of white blood cells, related to inflamation and immune response processes, and macromolecule metabolism.
Studies on cancer patients have shown that components from G. Lucidum support the immune system to fight off some types of cancer by boosting the function of natural killer cells (NK cells) whose primary function is to fight tumor cells.

Lingzhi Spores 80%
Lingzhi Extract 20%
Take 3 capsules twice daily with lukewarm water before meals
Not recommended for consumers with liver health concerns, pregnant women and children. Consult a physician before use.
Ganoderma lucidum (Reishi or Ling-zhi), a popular medicinal mushroom, is regarded by the Chinese as “mushroom of immortality”. It is believed that regular consumption of Ganoderma lucidum in the form of tea or mushroom powder can preserve the human vitality and promote longevity1. Scientific investigations have been conducted to show its anti-cancer, hypoglycemic and immuno-modulating effects. Its bioactive components comprise of triterpenes, polysaccharides and immune-modulatory proteins.
1. Shiao MS, Lee KR, Lin LJ, Wang CT. Natural products and biological activities of the Chinese medical fungus, Ganoderma lucidum. In: Ho CT, Osawa T, Huang MT, Rosen RT, editors. Food phytochemicalsfor cancer prevention. II. Teas, spices, and herbs. Washington,DC: American Chemical Society; 1994. p. 342–54.

1-. That it is true Reishi: in the market there are reishi extracts, reishi mycelium (mycelium of the reishi mushroom) and reishi spores (spores of the reishi mushroom). They are really different things!! For it to be reishi, the bottle or container must say: reishi mushroom powder. Look at the ingredients!
2-. That the reishi is micro ground: This technique breaks the mushroom cell walls and allows our gastric, intestinal juices, etc, to access the interior of the cells during digestion and consequently take out and use all their content. 1 gram of micro ground reishi can be equal to 3 g of another not micro ground reishi! (Depending on the grinding size)
3-. That it is clear of pollutants: the eco-label of the product will ensure much cleanness; however, the absence of heavy metals such as lead and cadmium, main pollutants of mushrooms, can only be found in some reishis in the market. A polluted reishi has the virtues of the reishi, but it will pollute us gradually too.
Photo of reishi (Ganoderma lucidum) located in a Mediterranean oak forest, in the province of Palencia.

Ganoderma lucidum (Reishi) is one of the oldest mushrooms known to be used medicinally by humans. It is highly prized as a major tonic in Chinese herbalism, with a powerful broad spectrum of health benefits. Often referred to as “the mushroom of immortality”, it has been valued as a longevity herb in Asian cultures for over 2,000 years.
Ganoderma lucidum (Reishi) is the foundation for Vida Divina’s existence. Our founder has a personal long-standing history with the health benefits of this powerful mushroom. We are proud to share it with the world.
- One of the oldest mushrooms to be used for health and well-being
- Asian cultures refer to it as “the mushroom of immortality”
- Highly prized as a tonic in Chinese herbalism
90 Capsules per Bottle
Suggested Use: Take 1 capsule daily or as directed by a health care professional.

Ganoderma Applanatum Extract Tincture Pure Wild Crafted
What is Ganoderma Applanatum as a Medical Mushroom?
Ganoderma Applanatum is often consumed as a tea and has a rich, smoky taste. It is used as a medical mushroom. Mushrooms like Ganoderma Applanatum and G. lucidum possess a number of useful polysaccharide constituents. More than 650 species of mushrooms from 182 genera have been described. The most valuable polysaccharides are beta-glucans, which are known for their immune-modulating and anti-tumor actions.
Source – Nootriment.com
Ganoderma Applanatum (Artist’s bracket, Artist’s Conk or Bear Bread) is a bracket fungus with a cosmopolitan distribution.
Order: Polyporales Family: Ganodermataceae Genus: Ganoderma Species: G. Applanatum
Ganoderma Applanatum Extract Tincture Properties and Health Benefits
“Like other species of the Ganoderma genus, Ganoderma Applanatum is comprised of roughly 400 different phytochemicals. It also contains bioactive triterpenes and polysaccharides that are being investigated for possible:
Traditional Use Of Ganoderma Applanatum
Ganoderma Applantum has been used in a number of traditional medicine systems. In traditional Chinese medicine (TCM), it is used to treat:
and reduce heat
The mushroom is traditionally consumed as a tea or a water-based extract. It’s flavor can change depending on its host tree. Consuming Ganoderma Applanatum has been said to provide energetic warmth.
A novel mero-triterpenoid in Ganoderma Applanatum was discovered in 2015. It has been named Applanatum A and it has a unique chemical composition. In preliminary studies, Applanatum A has been observed to demonstrate strong anti-fibrotic effects. Anti-fibrotic agents are said to block or prevent tissue scaring, causing regression of fibrosis.
Like Ganoderma Lucidum, this species of mushroom may have benefits for cancer prevention or treatment. However, research is still in the very preliminary stage.Ganoderma Applanatum has been observed to exhibit anti-tumor effects.

Reishi (Ganoderma lucidum), Chaga (Inonotus obliquus), Shiitake (Lentinula edodes), Maitake (Grifola frondosa), Organic Cane Alcohol 35-60%
Mushrooms strengthen the lungs and increase liver function. Mushrooms are known to protect the body against cancer causing agents. Reishi mushrooms are recognized in Chinese medicine as the “king of herbs.” They are grounding and assist us in cultivating inner stillness and increased concentration. This formula works on the whole person and is an excellent daily remedy for increased vitality.

- Zeng, Qinghai, Fang Zhou, Li Lei, Jing Chen, Jianyun Lu, Jianda Zhou, Ke Cao, Lihua Gao, Fang Xia, Shu Ding, Lihua Huang, Hong Xiang, Jingjing Wang, Yangfan Xiao, Rong Xiao, and Jinhua Huang. “Ganoderma Lucidum Polysaccharides Protect Fibroblasts against UVB-induced Photoaging.” Molecular Medicine Reports 15.1 (2016): 111-16. Web.

The triterpene content can also be used as a measure of quality of different ganoderma samples.
6 Scientifically Studied Benefits of Ganoderma Lucidum
1. Boost the Immune System
One of the most important effects of the reishi mushroom is that it can boost your immune system. While some details are still uncertain, test-tube studies have shown that reishi can affect the genes in white blood cells, which are critical parts of your immune system. What’s more, these studies have found that some forms of reishi may alter inflammation pathways in white blood cells.
Research in cancer patients has shown that some of the molecules found in the mushroom can increase the activity of a type of white blood cell called natural killer cells. Natural killer cells fight infections and cancer in the body.
Another study found that reishi can increase the number of other white blood cells (lymphocytes) in those with colorectal cancer. Although most immune system benefits of reishi mushroom have been seen in those who are ill, some evidence has shown that it can help healthy people, too. In one study, the fungus improved lymphocyte function, which helps fight infections and cancer, in athletes exposed to stressful conditions.
However, other research in healthy adults showed no improvement in immune function or inflammation after 4 weeks of taking reishi extract.
Overall, it is clear that reishi impacts white blood cells and immune function. More research is needed to determine the extent of the benefits in the healthy and ill.
2. Anti-Cancer Properties
Many people consume this fungus due to its potential cancer-fighting properties. In fact, one study of over 4,000 breast cancer survivors found that around 59% consumed reishi mushroom. Additionally, several test-tube studies have shown that it can lead to the death of cancer cells. Yet the results of these studies do not necessarily equate to effectiveness in animals or humans. Some research has investigated if reishi could be beneficial for prostate cancer due to its effects on the hormone testosterone. While one case study showed that molecules found in this mushroom may reverse prostate cancer in humans, a larger follow-up study did not support these findings. Reishi mushroom has also been studied for its role in preventing or fighting colorectal cancer.
Some research showed that one year of treatment with reishi decreased the number and size of tumors in the large intestine.

Reishi (れいし) belongs to the Polyporaceae, have an alias such as Ganoderma lucidum mushroom.
In rare varieties of plum trees 10万 book cannot be harvested only 2-3 never touch rarely noticeable.
1970S succeeded in the artificial cultivation in China and Japan.
Because of Ganoderma is easy as a health food, such as amino acids, proteins, sterols, alkaloids is the mechanism of action that clearly and specifically to what the ingredient is any work or not been clarified yet.
Has been known to pull the ability of body of Ganoderma, gradually improving the Constitution, strong body.
|Product name||Soul grass powder|
|Content amount||50 g|
|Country of origin / country of origin||China / Japan|
|To those who||Every day, for health
Is a health concern
|Product description||Reishi (れいし) belongs to the Polyporaceae, have an alias such as Ganoderma lucidum mushroom.|
|How to eat||One day as about 3-5 g in many eyes in warm water or water served.
Drink to eat by dividing in milk, soy milk, etc.
This product cannot be shipped to United States from the store.
Please contact the store for further information.

A member of the jelly fungus family, Tremella fuciformis grows on dead or fallen trees in tropical and subtropical climates, though it can also be found in temperate areas of North America, Europe, Asia, Australia, and New Zealand. It is thought to have anti-aging features, the ability to nourish lungs, and benefits for a healthy complexion.
In Japanese the Tremella fuciformis is called shiro kikurage, or “white tree jellyfish”. It is also known as silver ear mushroom and white wood-ear mushroom.
Polysaccharides consisting of D-mannan, glucuronic acid, xylose and fucose in Tremella were linked to improvement in subjective memory complaints and cognitive performance.
The antioxidants in Tremella fight damage from free radicals which offers anti-aging properties.
The polysaccharide glucuronoxylomannan in Tremella stimulates DNA synthesis in vascular endothelial cells which contribute to atherosclerosis, hypertension, and thrombophlebitis.
Exopolysaccharides extracted from Tremella may help control diabetes and reduce inflammation.
Tremella fuciformis also may be effective in fighting high cholesterol, cancer, and cough-related conditions.
Use of the turkey tail, or cloud mushroom, goes back to the Ming Dynasty in 15th century China. Brewed as a tea, its cloud-like appearance is thought to symbolize longevity, health, spiritual attunement, and infinity in Asian cultures. Turkey tail mushrooms are loaded with antioxidants, including 35 different phenolic compounds and flavonoids, quercetin and baicalein. So well-recognized is the use of turkey tail mushrooms that in the 1980s, Japan approved a cancer drug derived from it. In the U.S., the FDA approved the use of turkey tail mushrooms in 2012 to be used in combination with conventional chemotherapy treatments in clinical trials for several types of cancer.
Turkey tails are leather-like and wavy decorated with tan and brown concentric circles with a soft, velvet-like texture that have a similar appearance to the tail feathers of a turkey. Turkey tails are a polyspore species and if you have walked in the woods you likely have seen them growing on one of 70 different types of fallen trees and branches. Because they grow easily in any area where there are trees, they are among the most common mushrooms in the world.

Habitat and origin
Reishi is a woody fungus that grows mainly on the trunks of wild plum decomposition, sometimes those of oak or hemlock. Very rare in the wild, it grows only in the mountains, in deep forests. Nowadays, it is also grown in an artificial environment in China, elsewhere in Asia and North America, including Quebec.
Dosage of reishi
In Japanese and Chinese medicine, dosages typically range from 1.5 g to 9 g per day of dried fungus or the equivalent in the form of tablets, capsules or solid or fluid extract. Consult a trained practitioner for personalized treatment.
History of reishi
This fungus has for over 2000 years, an unusual reputation in Asia. It is mentioned in the oldest written in Chinese Pharmacopoeia (classical herbarium Seng Nong – published in 56 BCE) and it is believed that Asians knew reishi for centuries, even millennia before this time.
Traditional Chinese Medicine (TCM ) and , after him, the kempo medicine in Japan, take the flesh of reishi for a valuable tonic Qi (or Chi ) , the vital energy that supports the entire body. Therefore, it is assigned a global action such adaptogen in traditional medicine. For MTC, such substances have the power to strengthen the whole body and help maintain an optimal state of health and balance.
Reishi is particularly appreciated as it is extremely rare in the wild. It only grows in effect in deep mountain forests, usually on the trunks of plum decomposition, and it is found that 2 or 3 for 10,000 dead plum.
Although the Chinese have tried for centuries to grow reishi, it was not until the early 1970s that Japanese researchers have succeeded. From that moment, the fungus has become easily accessible to ordinary mortals. He was previously reserved for the privileged few who could afford the luxury of such a rarity.
Traditionally, there are 6 different varieties of reishi depending on the color (red, purple, blue, yellow, black or white). It was understood much later (in 1972) that these color differences are due to specific conditions of growth and not genetic variation within the species. It seems that fans prefer red reishi.
Nowadays, the fungus enjoys relative popularity among cancer patients.

Gupta et al., (2015) reported that Marchantia species are used in traditional Chinese medicine for protecting the liver and for treating hepatitis.
Reishi Mushroom is botanically known as Ganoderma lucidum and it belongs to the Ganodermataceae family. Reishi Mushroom is most prevalent in the Asian countries such as Japan, China, North and South Korea, Taiwan Indonesia and several other Asian countries. Reishi Mushroom is a broad, dark mushroom distinguished by its glossy exterior and woody texture. This suggests the origin of its name lucidum, which is derived from the Latin word “lucidus”. Lucidus simply connotes brilliant or shiny and this refers to the shiny surface of the Ganoderma mushroom.
Different parts of the Asian countries have different names for Ganoderma lucidum for example, the Japanese people refer to it as rōmaji, 霊芝, the Chinese people call it língzhī, Ling Zhi, pinyin or 靈芝 while the Vietnamese refer to it as linh chi. Ganoderma is considered a miraculous plant thus the reason it is mostly used for medicinal purposes, especially in the Asian continent. Ganoderma lucidum produces a group of triterpenes known as ganoderic acids. Ganoderic acids possess a molecular structure that is related to steroid hormones.
Other sterols found in reishi mushroom are; lucidadiol, ganoderol, ganodermadiol, ganoderiol and ganodermanontriol. Ganoderma also contains adenosine, alkaloids, coumarin, organic germanium, mannitol and polysaccharides (e.g. beta-glucan). Ganoderma lucidum has a strong bitter taste thus it is traditionally prepared as a hot water extract.
Li and Wang (2006) showed that a ganoderic acid isolated from Ganoderma lucidum exhibited inhibitory effects on the replication of hepatitis B virus (HBV) in HepG2215 cells (HepG2- HBV-producing cell line) over 8 days. This suggests that Ganoderma is effective for treating hepatitis.
Milk thistle is botanically known as Silybum marianum and belongs to the Asteraceae family. This plant is originally from Asia and Southern Europe before spreading to other parts of the world.

The influence of substrate on bioactivity and metabolites from fruit bodies
Metabolite production is often substrate dependent, and selected bioactive metabolites may be produced on selected substrates only (Shang et al. 2012), or produced in significantly different quantities (Sørensen and Giese 2013). Even minor variations in environment or nutrition have the potential to affect the quantity and diversity of fungal metabolites. The deliberate elaboration of cultivation parameters to influence the secondary metabolism of a strain has been called the OSMAC (one strain, many compounds) approach (Bode et al. 2002). Substrate modifications have already been used to enhance secondary metabolite production and bioactivity of the most popular medicinal polypores, i.e. Reishi (G. lucidum) (You et al. 2012) and Chaga (Inonotus obliquus) (Xu and Zhu 2011). In F. fomentarius, submerged culturing processes were optimized for the production of bioactive polysaccharides (Chen et al. 2008, Chen et al. 2011) and for laccase production (Neifar et al. 2011). Up to now, we are not aware of studies focusing on the effect of substrate on the bioactivity of medicinal polypore fruit bodies. Future studies based on fruit bodies cultivated under controlled conditions and on different substrates will help to elucidate this issue.
The medicinal potential of F. fomentarius, F. pinicola and P. betulinus
Our bioactivity screening generally confirms the potential of F. fomentarius, F. pinicola and P. betulinus as medicinal polypores. Because of their bioactivity against gram-positive bacteria, and their potency as antifungal agent, we especially consider F. pinicola to be worth further investigation on a molecular level. This fungus was widely applied in traditional European medicine, but its benefits and utilisation have been forgotten after the introduction of synthetic drugs. Due to renaissance of naturopathy and also due to increasing bacterial and fungal resistances, working with traditional medicinal fungi is becoming increasingly interesting and rewarding.

Ganoderma Lucidum, also known as Gano, Reishi or Lingzhi, has a 4,000 year history in Traditional Chinese Medicine, and is considered to be of the highest class of tonics. It is particularly renowned for its use in promoting longevity, supporting liver function, and is reputed to reduce hypertension. It has been used in China as a panacea to alleviate things from everyday nuisances like the common cold or skin disorders to terminal conditions such as cancer. In recent years the focus of research with Reishi is its apparent immuno-enhancing and anti-tumor activities.
While the exact mechanism is still unknown, a large numbers of studies have shown that Reishi may modulate many components of the immune system such as the antigen-presenting cells, NK cells, T and B lymphocytesm, which are pivotal to initiating a primary immune response. It is believed that it may be through this immune modulation that reishi’s apparent anti-tumor effect may be achieved.
Click here for a research article written by by a Leukemia Research organization. We have also provided links for a number of other research studies below, including studies published on PubMed.gov. Another website with some very interesting research on Ganoderma Lucidum is ClinicalTrials.gov. This website includes studies on the effect Ganoderma Lucidum has on Cancer in Children, Rheumatoid Arthritis and Early Parkinson’s Disease.
Ganoderma for Man’s Best Friend
Today, new uses for reishi mushrooms are being discovered, even in veterinary medicine. Doctors and Scientists reveal the power of ganoderma reishi in the human body and for dogs. As more and more professionals consider homeopathic treatments for pets, one major herbal contender is knocking out all the competition. And the winner, as usual, is Ganoderma lucidum. Sometimes, you just have to say “Wow — how can one little mushroom do so much?!”
University of Florida Veterinary Scholar Dr. R.M. Clemmons suggests in his article “Integrative Treatment of Cancer in Dogs” shoring up your pup’s immune system with regular doses of Ganoderma lucidum, the powerful little ‘mushroom that enriches all our GanoCafe products! In addition to Ganoderma’s seeming positive effects in fighting canine diseases, Dr.

191-200, retrieved 20th August 2018, https://www.ncbi.nlm.nih.gov/pubmed/18997282
Wachtl-Galor, S, Teun J, Buswell J.A & Benzie I, Herbal Medicine: Biomolecular and Clinical Aspects, 2nd ed, chapter 9 Ganoderma lucidum (Lingzhi or Reishi), Taylor and Franics, retriveid 20th August 2018, https://www.ncbi.nlm.nih.gov/books/NBK92757/
Sanodiya, BS, Thakur GS, Baghel RK, Parasad GB & Bisen PS 2009, ‘Ganoderma lucidum: a potent pharmacological macrofungus’, Curr Pharm Biotecnol, vol. 10, no. 8, pp. 717-742, retrieved 20th August 2018, https://www.ncbi.nlm.nih.gov/pubmed/19939212
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- Jesenak, Milos, Slavomir Urbancek, Juraj Majtan, Peter Banovcin, and Jana Hercogova. “Î²-Glucan-based Cream (containing Pleuran Isolated Frompleurotus Ostreatus) in Supportive Treatment of Mild-to-moderate Atopic Dermatitis.” Journal of Dermatological Treatment 27.4 (2015): 351-54. Web.
- Kurtipek, Gulcan Saylam, Arzu Ataseven, Ercan Kurtipek, Ilknur Kucukosmanoglu, and Mustafa Rasid Toksoz. “Resolution of Cutaneous Sarcoidosis Following Topical Application of Ganoderma Lucidum (Reishi Mushroom).” Dermatology and Therapy 6.1 (2016): 105-09. Web.
- Lin, Kai-Wei, Yen-Ting Chen, Shyh-Chyun Yang, Bai-Luh Wei, Chi-Feng Hung, and Chun-Nan Lin. “Xanthine Oxidase Inhibitory Lanostanoids from Ganoderma Tsugae.” Fitoterapia 89 (2013): 231-38. Web.
- Rios JL. “Effects of triterpenes on the immune system”. J Ethnopharmacol. 2010;128(1):1-14
- Shen, Tao, Chao Duan, Beidong Chen, Meng Li, Yang Ruan, Danni Xu, Doudou Shi, Dan Yu, Jian Li, and Changtao Wang. “Tremella fuciformis Polysaccharide Suppresses Hydrogen Peroxide-triggered Injury of Human Skin Fibroblasts via Upregulation of SIRT1.” Molecular Medicine Reports (2017): n. pag. Web.
- Tie, Lu, Hong-Qin Yang, Yu An, Shao-Qiang Liu, Jing Han, Yan Xu, Min Hu, Wei-Dong Li, Alex F. Chen, Zhi-Bin Lin, and Xue-Jun Li. “Ganoderma Lucidum Polysaccharide Accelerates Refractory Wound Healing by Inhibition of Mitochondrial Oxidative Stress in Type 1 Diabetes.” Cellular Physiology and Biochemistry 29.3-4 (2012): 583-94. Web.

Chinese tradition refers to the reishi mushroom (Ganoderma lucidum) as ‘the lucky fungus’, for its powers in alleviating complaints such as arthritis, insomnia and chest tightness. And 2,000 years after its first use, the ancient remedy is still proving somewhat of a charm, after researchers from the University of Haifa announced their success in preliminary efforts to slow the growth of prostate cancer cells using reishi extracts.
The scientists, led by Dr Ben-Zion Zaidman of the university’s Institute for Evolution, found that molecules extracted from Ganoderma lucidum
blocked the action of androgen – the male sex hormone – upon cancerous cells. Without intervention, said Zaidman, the hormone otherwise works as a chemical ‘switch’, stimulating the cells – especially in early stages of the disease – to multiply uncontrollably into tumor tissue.
“These results give rise to hope about developing new medications to treat prostate cancer,” said Zaidman.
While the research is still in the petri-dish stages, stresses Zaidman, one day it could lead to a new way to combat the disease, which every year is diagnosed in nearly 700,000 men worldwide, including Israeli Prime Minister Ehud Olmert.
Existing drugs, such as Flutamide, also work by interfering with the action of androgen receptors. But the mushroom extract molecules, said Zaidman, had a far more dramatic effect.
“The extracts worked in a different way. We think they actually prevented androgen receptors from binding to the DNA,” he told ISRAEL21c.
The reishi, a fungus native to densely wooded areas in North America, Europe and Asia has been used in traditional medicines for centuries – and is currently experiencing renewed popularity among the health-conscious, popping up on the shelves of health food stores and organic supermarkets around the world.
“Recently, mushroom extracts of every kind have become available,” notes Zaidman. “But the preparations are water soluble and very weak. You’d have to eat a lot of mushroom soup to get any kind of effect,” he laughed.
Eschewing the kitchen in favor of the laboratory, his team has spent the last three years cooking up active metabolites using alcohol-based solvents. They will now seek to pinpoint the precise relationship between the chemical structures and their cell-based activity, refining the crude extracts into isolated molecules.
If they succeed in their research, then it will confirm the long-standing notion that the reishi mushroom is very lucky indeed.

Ganoderma Lucidum Spirulina Capsule [Large Bottle]
[Ingredients] 100% organic Ganoderma lucidum powder, spirulina.A kind of natural,organic food to your health.
It adopts log-cultivated Ganoderma lucidum and spirulina as main ingredients by using modern bio-technology. Richly contains Ganoderma lucidum polysaccharide, triterpene Ganoderma lucidum acid, protein, γ-GLA, vitamin, micro-mineral and so on. Long-term usage will relief the fatigue and facilitate fat metabolism, renew and activate the effectives of brain cells to improve overall immunity.
1. Natural product for beauty care, facilitate metabolism, anti-oxidation and nourish skin deeply.
2. Computer operator, worker who contacts radioactive ray will anti-radicalization, anti-fatigue and regulates incretion system in human body.
3. Has good efficacy on the treatment of high blood pressure, high blood fat, high blood sugar for immune support, resistance to disease.
[Usage & Dosage]
2-4 Ganoderma Lucidum Spirulina Capsules each time, 3 times daily before meals or take as recommended.

“Fast shipping nice contact, always answers.
Happy to help and high quality cultures. Thanks for the goodies. -Victoria A., Funginomi Customer
Hardwood, mostly, beech, oak rarely on coniferous wood, annual, regionally rare, easy to cultivate.
This mushroom is used in the Chinese and japanese medicine a long time and has shown to help with a lot of things. The most researched part of this mushroom are its glucans called polysaccharides.
-accompanying therapies, transplants and after cancer therapies
-for nervous weakness, sleep disturbances, arthritis, allergies and, liver cirrhosis, cardiovascular problems, muscle diseases, dizziness, asthma, hepatitis A, B, C, obesity
-preventive or concomitant chronic inflammatory diseases of the kidneys, stomach, spleen, liver, lungs and heart
Buy ANY 3 Cultures – We GIFT you 1 of them
11,99 € – 39,99 €
Liquid Cultures (10mL) are a mix of nutrients, desolved in water and pressure sterilized. Perfectly a monoculture is then innoculated, to prevent competition. Some species need extra nutrition, so the mycelium grows healthy prior to inoculation.
It is very effective and just a small amount is enought to inoculate a big amount of spawn or soil.
This Slants (50mL) can keep your cultures viable for many years, if treatened right. Also there is no more issue with condensation.
If you can work with petri dishes you will have no problem with these. Petris are better suited for short term storage or to multiply strains.
We will set a culture on a fresh Petri Dish (Ø90mm) for you. It will then grow out and if it withstands quality control, it will be sent. Petris are perfectly suited for short term storage, to multiply strains, to cross species and to clean up cultures. You may use a small cut of this cultures to innoculate substrates.
Our Grain Spawn (1L) contains a variety of different nutrient sources, which means we use different types of seeds. It is soaked and then sterilized at >121°C to kill any competing organisms. We then inject a species. After proven purity, we ship it fresh to you.
How long it needs? Check the Spawn Run Time @Parameter.

The polysaccharide content of reishi mushroom is responsible for possible anticancer and immunostimulatory effects.
Hailed in ancient Eastern medicine as the ``mushroom of immortality`` and the ``medicine of kings,`` you'd expect reishi to offer you some pretty astounding health benefits, right?
Ganoderma is not often used in cooking because they are hard and have a bitter taste.
For over 2,000 years, the Reishi mushroom (Latin: Ganoderma Lucidium Chinese: Lingzhi) has been revered as one of the most sought-after and powerful tonics.
In China and Japan, Reishi mushroom has been used for more than 4,000 years to treat a variety of ailments.
Reishi mushroom is a fungus that some people describe as “tough” and “woody” with a bitter taste.
The reishi mushroom actually brings your candida index down. So, if you’re battling candida, like so many of us are -- this herb may be an excellent addition to you healing.
The water-soluble polysaccharides, are active ingredients found in the red reishi mushroom
In China, reishi mushroom is considered one of the best herbs to increase longevity. This adaptogenic mushroom has been shown to:
I asked an elderly Japanese friend why she looks so young for her age. She said she drinks tea made with reishi mushrooms.
You have probably heard them being touted as a great medicinal mushroom and a wonderful healer.
Widely known as an immune modulator, this gorgeous mushroom is also a superb nervous system tonic, both soothing and restorative.

Anti many forms of cancer realtors around health theoretically written and published around February 2010 (2020) Chemical make up (anticancer representative around Prescription drug Chemistry) written and published a study final result written and published by way of Teacher Li Peng, Education with treatment, Fujian Health Higher education. By mobile phone plus puppy experiments, the following analysis affirmed the fact that impartial triterpenoids around Ganoderma lucidum might a lot stop a advancement with intestines many forms of cancer, and also its particular apparatus relates to “promoting many forms of cancer mobile phone apoptosis”.
Considering may initially uncovered a triterpenoids with Ganoderma lucidum around 1982, them but not only provides for a research outline to get “why a fruiting shape with Ganoderma lucidum is very bitter”, and provides for a ganoderma lucidum beta glucan vision to get may to study “why Ganoderma lucidum might reject tumors”.
“Ganoderma triterpenoids” is actually a group name, which will frequently is the word for a dynamic pieces by using terpenoid shape around Ganoderma lucidum. Reported by its several chemical like components, they usually are torn within not one but two categories: a person set is definitely “acid triterpenoids” like ganoderic acids, other set is definitely “acid triterpenoids” like ganodermal drinking “Neutral triterpenes” like alcohols), should the not one but two groups of triterpenes will be bundled, its labeled “total triterpenes”.
Compared to a antitumor outcome with whole triterpenoids plus plaque created by sugar triterpenoids with Ganoderma lucidum, there are plenty of research evidences, as well as homework for impartial triterpenoids with Ganoderma lucidum is definitely rather very few, hence Teacher Li Peng’s company specializes in the following section.
People made use of a fruiting shape with Ganoderma lucidum as being the trial and error fabric, initially made the sum of triterpenoids with Ganoderma Lucidum by using ethanol, in that case further more taken away from a impartial triterpenoids plus plaque created by sugar triterpenoids, so that you can take a look at its inhibition for intestines many forms of cancer.

Unlike other mushrooms, research shows maitake to be almost as effective administered orally as intravenously. One polysaccharide fraction called MT-1, or simply the D-fraction, showed significant activity when administred orally. It is an alkali-soluble, hot water extractable compound that contains approximately 30% protein, or a ratio of beta-glucan to protein of 7:3. It occurs in a concentration of .04 mg. per gram of dried maitake mushrooms. Dried maitake mushrooms and taplets provide a safe, non-toxic, therapeutic effect. Garuda's maitake extract is made from high quality cultivated mushrooms grown naturally without pesticides or chemicals of any kind. We have the maitake extract available in two different concentrations,10:1 and 4:1.
Mushroom extracts can be considered some of the first nutraceuticals - food concentrated into medicinal form. Garuda's extracts are carefully produced according to cGMP standards from select raw materials. Many of our extracts are standardized to contain guaranteed levels of active compounds.
Aoki, T. 1984. Lentinan. In Immune Modulation Agents and Their Mechanisms. R.L. Fenichel and M. A. Chirgis, eds. Immunology Studies. 25:62-77., Bo, L. and Bau Yun-sun. 1980. Fungi Pharmacopoeia (Sinica). Oakland: Kinoko Co., Chang, H.M. and P. Pui-Hay But. 1987. Pharmacology and Applications of Chinese Materia Medica. Vol. 2. Singapore: World Scientific., Chang, H.M., ed. et al. 1984. Advances in Chinese Medicinal Materials Research. Singapore: World Scientific., Huidi, F. and W. Zhiyuan. 1982. The clinical effects of Ganoderma lucidum spore preparations in 10 cases of atrophic myotonia. J. Trad. Chin. Med. 2:63-65.,Miller, D. 1994. Current clinical protocol submitted to the N.I.H. Scientific Director Cancer Treatment Research Foundation, Arlington Heights, IL.,Nanba, H. 1994a.

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Ganoderma Lucidum Side Effects
If you’ve ever taken natural or herbal medicine especially those that qualify as TCM (Tradition Chinese Medicine), there is a risk that some minor discomforts might occur during the healing process. An example would be if you've experienced acne, you know there is usually a phase where it seems the acne is getting worst before it gets better. Another example would be how a healing wound begins to excessively itch while repairing itself. Ganoderma can cause negative side effects that cause temporary reactions within the body during the healing process.
Common side effects that occur when Ganoderma is ingested includes increased breakouts of acne, reddish pimply dots, and/ or other skin rashes, dizziness, digestive issues, higher blood pressure, stomach ache, or swollen legs. However, an individual may experience some or none of these temporary adverse reactions as circulatory blockage or toxins are being removed from the body.
Warnings: If you are a diabetic taking hypoglycemic drugs please do not take Ganoderma or any other TCM without consulting with a medical professional before doing so. Ganoderma can possibly cause fluctuations in blood sugar that could cause a problem with diabetes. Individuals on blood pressure medications should monitor pressure levels consistently as well since this product may cause temporary higher blood pressure until the end results of a lowered pressure is attained.
Ganoderma or Reishi Mushroom – Hype or a Healing Miracle?
Case Studies and Personal Experiences
As the first video stated the Chinese have been conducting research on the ling zhi since the ’50s. However, other eastern and western studies are being conducted on this mushroom. Most of the studies will not give a ‘concrete finding' which is true with many alternative medicines. However, many are stating ‘it appears’ to assist in all the benefits named before such as reducing skin inflammation, increasing the immune system, treating blood and circulatory conditions, and preventing some cancers. You can find more reading on these case studies at the end of this section.
I cannot provide much of a personal experience with ganoderma because I’ve only been drinking the coffee for a short time. However, I can share personal testimonies of friends and family that have been using the products of Organo Gold for some time now. One individual suffers with psoriasis and she has seen an improvement in her overall skin condition.

Throughout Asia, especially China as well as Japan, mushrooms have belonged to the culinary experience but most importantly, they have actually harnessed the largest wellness advantages of mushroom extracts for hundreds of years.
The western perspective and lack of nutritional details of mushrooms has actually landed our fungal good friends in our salads as well as sliced up in our kitchen areas to be utilized in food meals. The Asian culture nonetheless, has for a number of thousand years, made use of specific mushrooms to boost and also preserve better wellness. A number of these mushrooms have understood health and wellness advantages to include anti-aging residential or commercial properties to striking cancer cells and also although relatively brand-new to the Western world, continue to be utilized within the Eastern society for their medical residential properties.
With advances in mushroom farming in just the last two decades, enhanced availability, research, and affordability, use of mushrooms for their wellness advantages has actually increased. As an example, the Reishi Mushroom (Ganoderma Lucidum) was originally only available to Asian royalty and also commonly described as mushroom of everlasting life. Reishi can subdue cell adhesion as well as migration of specific cancer cells, potentially minimizing malignant impacts as well as absolutely increasing immune systems.
The tumor inhibiting capability of certain mushrooms is produced by the immune-stimulating polysaccharides. Medical practitioners in China and also Japan have used mushrooms in addition to herbs in anti-aging and also cancer cells medicines. Absolutely, the holistic area has actually expounded on the wellness advantages of utilizing such essences.
When selecting mushroom essence items for human consumption, it is very important to select alcohol based extracts as they remove water-soluble parts from the mushroom to take full advantage of readily available triterpinoids. This is very essential in accurate analysis of degrees of Ganoderic acids to figure out potency. Reishi is the just recognized source of a group of triterpenes called ganoderic acids, which have a molecular framework comparable to steroid hormonal agents. It has one of the most energetic polysaccharides among medical plant resources. In addition to various other treating qualities, some think these Ganoderic acids may even decrease high blood pressure as well as cholesterol levels. Different mushrooms continue to be the focus of specialized research study in cancer as well as immune disorder.
Nutr Cancer. 2005; 53( 1 ):11 -7.

Institut für Pharmazie, Ernst Moritz Arndt Universität Greifswald, Friedrich-Ludwig-Jahn-Strasse 17, 17487 Greifswald.
The medicinal use of mushrooms, so-called higher fungi, has a very long tradition in the Asian countries, whereas their use in the Western hemisphere has been slightly increasing only since the last decades. The paper gives an overview about the most important medicinal mushrooms and summarizes the actual knowledge about chemistry and pharmacology of Lentinula edo-des (Shiitake, Golden Oak Mushroom), Ganoderma lucidum (Reishi, Ling Zhi), Agaricus brasiliensis (Royal sun agaricus), Grifola frondosa (Maitake, Hen-of-the-Woods) and Hericium erinaceus (Yamabushitake, Lion's Man, Monkey's Head).
Mistaking toxic mushrooms for edible ones is common and sometimes deadly. Even for experienced foragers it can be difficult to tell what is poisonous and what is not.
Amanita Mushroom - Amanita is the most recognizable toxic mushroom. Amanita phalloides mushrooms, commonly known as "death caps," can easily be confused with other common species such as parasols. Eating them can cause severe damage to the liver and kidneys, followed by death within five to 10 days.
Gyromitra mushroom or false morrel (monomethylhydrazine) poisoning may be partly treated with pyridoxine.
Different varieties of
Agaricus mushroom include:
Agaricus bisporus mushroom is a common, edible, cultivated mushroom also known as white mushroom. The lectin from the common mushroom Agaricus bisporus, the most popular edible species in Western countries, has potent antiproliferative effects on human epithelial cancer cells, without any apparent cytotoxicity. This property confers to it an important therapeutic potential as an antineoplastic agent. Agaricus campestris - also known as meadow mushroom
Agaricus blazei is an edible and medicinal mushroom. Agaricus blazei is also known as the Brazilian sun mushroom or himematsutake.
Agaricus subrufescens Peck was cultivated first in the late 1800s in eastern North America. Once a popular market mushroom, this agaricus species faded from commerce in the early 20th century.

Of course something this versatile has many uses and a fraction of them are: Tonic, immune booster, allergies, blood pressure stabilizer, altitude sickness, chemotherapy support, HIV support, fatigue, high blood pressure, high triglycerides, hepatitis, inhibits platelet aggregations.
Below are the remarkable result of Ganoderma efficacies from scientific research...
Cordyces Sinensis Extract
Cordyceps, one of the better-known traditional Chinese medicines, consists of the dried fungus Cordyceps sinensis growing on the larva of the caterpillar. It is commonly used in China for the replenishment of general body health. Cordyceps has a broad range of pharmacological and biological actions on the liver, kidneys, heart, and immune system.
One of the known pharmacological effects is its anti-oxidation activity. Cordyceps sinensis, a well-known and valued traditional Chinese medicine, is also called DongChongXiaCao (winter worm summer grass) in Chinese.
Cordyceps is recognized as a health supplement in Chinese traditional medication and is also on of the top 3 China most valuable herbs besides Ginseng and Deer's antters. According to the ancient book of record, Cordyceps have the effects in prolonging and strengthening lives, anti-aging, help in lung breathing and very effective in curing erectile dysfunction.
Cordyceps contains Cordyceps polypeptide, which is the most precious active ingredients in Cordyceps. It is extracted using high technology. Even a small amount of Cordyceps polypeptide has remarkable result because its tiny molecules allow it to be easily absorbed into our body.
Some of Cordyceps medicinal efficacies are...
Cynomorium Songaricum Extract
Cynomorium is known in Chinese as suoyang, which is based on the herb's medicinal effects, "locking the yang." It is obtained mainly from the East Asian species, Cynomorium songaricum, though the similar C. coccineum is sometimes utilized as a substitute.
The plant harvested for Chinese medicine grows at high altitude, mainly in Inner Mongolia, Qinghai, Gansu, and Tibet. Songaria Cynomorium Herb is the dried fleshy stem of Cynomorium songaricum Rupr. (Fam. Cynomoiaceae).

Since only three nucleotide sequences of this species (COI, 16S rRNA, and 18S rRNA) appear in the GenBank database so far, no analysis of the molecular mechanisms underlying E. fullo's resistance to insecticide and environmental stress has been accomplished. We reported a de novo assembled and annotated transcriptome for adult E. fullo using the Illumina sequence system. A total of 53,359,458 clean reads of 4.8 billion nucleotides (nt) were assembled into 27,488 unigenes with an average length of 750 bp, of which 17,743 (64.55%) were annotated. In the present study, we identified 88 putative cytochrome P450 sequences and analyzed the evolution of cytochrome P450 superfamilies, genes of the CYP3 clan related to metabolizing xenobiotics and plant natural compounds, in E. fullo, increasing the candidate genes for the molecular mechanisms of insecticide resistance in P450. The sequenced transcriptome greatly expands the available genomic information and could allow a better understanding of the mechanisms of insecticide resistance at the systems biology level.
Yu, Guo-Jun; Wang, Man; Huang, Jie; Yin, Ya-Lin; Chen, Yi-Jie; Jiang, Shuai; Jin, Yan-Xia; Lan, Xian-Qing; Wong, Barry Hon Cheung; Liang, Yi; Sun, Hui
Background Ganoderma lucidum is a basidiomycete white rot fungus and is of medicinal importance in China, Japan and other countries in the Asiatic region. To date, much research has been performed in identifying the medicinal ingredients in Ganoderma lucidum. Despite its important therapeutic effects in disease, little is known about Ganoderma lucidum at the genomic level. In order to gain a molecular understanding of this fungus, we utilized Illumina high-throughput technology to sequence and analyze the transcriptome of Ganoderma lucidum. Methodology/Principal Findings We obtained 6,439,690 and 6,416,670 high-quality reads from the mycelium and fruiting body of Ganoderma lucidum, and these were assembled to form 18,892 and 27,408 unigenes, respectively. A similarity search was performed against the NCBI non-redundant nucleotide database and a customized database composed of five fungal genomes.

Maitake (Grifola Frondosa)
It’s said that the maitake, or “dancing mushroom,” got its name because Japanese villagers would dance for joy when they found the rare and valuable species in the deep mountain valleys of Japan.
Other commonly known names for maitake are Hen of the Woods and Ram’s Head. Its scientific name is Grifola Frondosa.
The maitake goes through drastic changes as it matures. It starts out growing in clusters of gray overlapping mounds. These mounds are the caps of the mushroom, which share the same stem and look similar to a cauliflower. As the entire specimen continues to grow, the caps spread and fan out becoming a dark gray or brown color.
When the maitake reaches maturity its color fades. Sometimes maitake turn into a light gray, yellowish color. The edges of the caps become brittle and fragile while the base and stems remain firm.
For centuries in Japan and China, maitake mushrooms were harvested specifically for their medicinal and healing capabilities.
Northern temperate areas are the most common place for maitake to grow. They also prefer midrange temperatures, which is why they grow most fruitfully in the fall season of the northeastern regions of Japan and North America.
Maitake are generally found in the wild on stumps, or at the base of dying hardwood trees. It is common for Maitake to grow at the foot of decaying oaks, elms, maples, beech, blackgum, and larch trees.
Natural Cultivation Methods
The most successful outdoor cultivation methods for maitake are the log and stump methods. For these methods, the user should use hardwoods to achieve the greatest fruiting.
Generally, the stump cultivation technique will take a maitake-inoculated hardwood stump at least 2-3 years before it begins to fruit. However, it will produce in large volumes once fruiting begins.
Fruiting Cycles & Yield Potentials
If exercising the indoor cultivation method, you should inoculate a combination of sterilized sawdust, chips and bran for best results. This is the combination of ingredients that we use for our Maitake Mushroom Farms.
Mushroom Shack’s Maitake Mushroom Farm will produce between ½ and 1 lb of mushrooms throughout the entire fruiting cycle. The fruiting cycle will begin between 6 and 8 weeks after inoculation.

- Original article
- Open Access
Fungal strain matters: colony growth and bioactivity of the European medicinal polypores Fomes fomentarius, Fomitopsis pinicola and Piptoporus betulinus
AMB Express volume 5, Article number: 4 (2015)
Polypores have been applied in traditional Chinese medicine up to the present day, and are becoming more and more popular worldwide. They show a wide range of bioactivities including anti-cancer, anti-inflammatory, antiviral and immuno-enhancing effects. Their secondary metabolites have been the focus of many studies, but the importance of fungal strain for bioactivity and metabolite production has not been investigated so far for these Basidiomycetes. Therefore, we screened several strains from three medicinal polypore species from traditional European medicine: Fomes fomentarius, Fomitopsis pinicola and Piptoporus betulinus. A total of 22 strains were compared concerning their growth rates, optimum growth temperatures, as well as antimicrobial and antifungal properties of ethanolic fruit body extracts. The morphological identification of strains was confirmed based on rDNA ITS phylogenetic analyses. Our results showed that species delimitation is critical due to the presence of several distinct lineages, e.g. within the Fomes fomentarius species complex. Fungal strains within one lineage showed distinct differences in optimum growth temperatures, in secondary metabolite production, and accordingly, in their bioactivities. In general, F. pinicola and P. betulinus extracts exerted distinct antibiotic activities against Bacillus subtilis and Staphylococcus aureus at minimum inhibitory concentrations (MIC) ranging from 31-125 μg mL−1; The antifungal activities of all three polypores against Aspergillus flavus, A. fumigatus, Absidia orchidis and Candida krusei were often strain-specific, ranging from 125-1000 μg mL−1. Our results highlight that a reliable species identification, followed by an extensive screening for a ‘best strain’ is an essential prerequisite for the proper identification of bioactive material.
Polypores are a diverse group of Agaricomycetes (Basidiomycota) with tough poroid hymenophores.

Curative properties possess not only mushrooms, but also their underground part (mycelium). The extract from a mycelium meytake strengthens immunity, and hats of these mushrooms are capable to regulate pressure, the maintenance of glucose, insulin and bilirubin in blood, to restore balance of sexual hormones at endocrine diseases, to reduce level of cholesterol and to promote disposal of excess weight. Meytake it can be used for preventive maintenance and treatment of infectious and bacterial diseases. Mushrooms meytake are rich with minerals (potassium, calcium, magnesium), vitamins (B2, D2), cellulose and amino acids. According to the newest researches, meytake can prevent development of tumours and lower chemotherapy by-effects.
Reishi (Ganoderma lucidum) it is considered a mushroom of immortality and the strong means giving spiritual force. There is a set of subspecies reishi, many of which are not studied yet. Mushrooms reishicontain only 75 % of water while many other mushrooms on 90 % consist of water. Unlike many other mushrooms, medical properties reishi are concentrated in legs, instead of in hats. For the first time mushrooms reishi have been described about 2000 years ago. Ancient Chinese doctors carried them to medicines of the first category which restore balance of an organism and have no by-effects.
Reishi, as well as other mushrooms in east medicine, it is used for strengthening of immunity, struggle against a cancer and many chronic diseases caused by infringements of circulation of liquids in an organism. Mushrooms reishi stabilise pressure, cholesterol and sugar in blood, prevent infectious diseases and even treat such indispositions as a sleeplessness and cold. Mushrooms reishi are very effective at allergy treatment. The extract reishi also can be applied to treatment of infringements of nervous system.
Cordyceps sinensis – the Chinese Caterpillar Mushroom – grows in mountains at height to 5000 m. This mushroom is interesting to that “eats” caterpillars, killing them and growing from their body. To cultivate cordiceps it is uneasy, therefore it long time remained very expensive and unknown outside of China. In the Chinese medicine this mushroom is used for balance and toning by In and Jan.

They can be utilised to spice up your immune system and may well in addition enhance the overall performance of antioxidant nutritional nutrients although the 2 chemical compounds are utilized alongside one another.
Reishi mushrooms are considered toward suppress tumor progress and are often applied within cancer avoidance initiatives for this purpose. Russian experts upon the Greatest cancers Examine Heart inside of Moscow comprise experienced constructive outcomes applying reishi extracts towards spice up the immunity of utmost cancers sufferers.
Anti-tumor and immunoregulatory actions of Ganoderma lucidum and its achievable mechanisms.
Acta Pharmacol Sin. 2004.
Possibly the greatest attractive persona of this style of medicinal fungus is its influence on the immune system and anti-tumor things to do. Huge figures of research contain listed that reishi modulates countless variables of the immune process these kinds of as the antigen-presenting cells, NK cells, T and B lymphocytes. The water extract and the polysaccharides portion of reishi displayed substantial anti-tumor impact in number of tumor-bearing pets fundamentally by course of its immune system improving upon recreation. Most recent review in addition confirmed that the alcohol extract or the triterpene portion of reishi possessed anti-tumor effect, which appeared to be affiliated in the direction of the cytotoxic exercise in direction of tumor cells straight. Original research indicated that antiangiogenic influence may be concerned antitumor activity of reishi.

Our Mediterranean strain (IB20130033) was placed within another, distinct clade of F. fomentarius sequences originating mostly from Southern European countries (Italy, France, Portugal, Slovenia) and other substrates (Platanus x acerifolia, Populus spp., Quercus spp. and Abies). The only exceptions are F. fomentarius sequences from the Slovak Republic. This Southern European clade is sister to a distinct clade of F. fomentarius from China.
Within clade sequence divergence was small, with 0-3 base pair differences between the different strains of F. fomentarius from Northern European countries. Sequence divergence between the Northern and Southern European clade was 9-18 base pairs, and sequence divergence to the outgroup F. fasciatus was 41-62 base pairs.
Phylogenetic placement of F. pinicola strains
F. pinicola is a polypore with very little sequence divergence between strains. Only sequences from USA or Asia showed some sequence divergence in addition to F. ochracea, which forms a distinct clade within F. pinicola, thus making this clade paraphyletic (Figure 5). We found very little sequence divergence between all our strains: Sequence divergence to other isolates of F. pinicola was 1-5 base pairs out of 504 positions, to other species of Fomitopsis (F. meliae, F. palustris) 15-21 base pairs.
Phylogenetic placement of P. betulinus strains
P. betulinus is a polypore species with little rDNA ITS sequence variation between different strains from a broad geographic area (Europe, Russia, East Asia) and Betula spp. or Acer saccharum as substrate (Figure 6): Within species sequence divergence was very low: P. betulinus sequences differed only in 1-2 out of > 500 base pairs from each other, but had 44-45 differed base pairs when compared to the sister taxon P. soloniensis.
Fungal strain matters
Our results confirmed our hypothesis that medicinal polypore strains belonging to the same lineage differ significantly in their qualitative and quantitative secondary metabolite production, and in bioactivity. This confirms earlier studies focusing on other medicinal polypore species showing that the fungal strain used is important for the chemical composition of fruit bodies (Agafonova et al.

This also allowed for a comparison of strains based on both, bioactivities of fruit body extracts and the physiological properties of cultures in vitro.
Physiological properties are often used for species delimitation because they reflect genetic distance: Fomes strains belonging to different species have different physiological properties, like colony growth responses to temperature (McCormick et al. 2013). The question whether also strains within one species, e.g. F. fomentarius, differ in growth responses to temperature was not addressed so far.
The main aim of this work was to study the influence of fungal strain (isolate) of three selected, medicinal polypores on their antimicrobial bioactivity and physiological properties. The bioactivity was assessed for ethanolic extracts from the same fruit bodies, which had been used for isolation of mycelial cultures. Bioactivity was tested against potentially pathogenic fungi and bacteria. Physiological properties of mycelial cultures (colony growth rate and optimum temperature) were investigated under standard in vitro conditions. All polypore strains used were characterized by rDNA ITS sequences, and phylogenetic analyses were carried out to verify species identification. The potential influence of geographic provenance and substrate on strain evolution and properties are discussed.
Material and methods
Organism collection, identification, culture
F. fomentarius, F. pinicola, and P. betulinus fruit bodies were mainly collected in Tyrol, Austria in 2013. Fruit body vouchers were deposited in the Mycological Collection of the Herbarium Innsbruck (IB), cultures were deposited in the Jena Microbial Resource Collection (JMRC), sequences were deposited in GenBank. Voucher numbers, GenBank accession numbers, JMRC collection numbers, plant hosts, as well as habitat information are given in Table 1.
Sterile techniques were used to obtain cultures from the context tissue. Small pieces of context tissue (2.0 mm3) were excised from each basidiome, plated on 2-3 % w/v malt extract agar plates (MEA Art. Nr. X976.2 from Roth Karlsruhe Germany) and incubated for one to three weeks at a temperature of 20°C. Cultures were checked regularly for contaminations. Mycelial plugs of 1-3 mm in diameter were taken from the edge of the mycelium and transferred to new plates, to establish pure cultures and further carrying out growth experiments.

“In Western medicines, many of the notable natural drugs are formulated through the process of purification. As most of the medicinal formulations today more often than not produce side effects in the human body, it has become the keen pursuit and ultimate objective of Western medicines to develop drugs that do not entail such unfavourable effects. This is however something that we have already achieved, as consuming Lingzhi in large amounts is known to bring no side effect. On top of this, research findings also point to the fact that Lingzhi triterpenoids promise the greatest potential in being developed into highly effective crude drugs. As a business entity equipped with the most resourceful corporate strength in the world pertaining to the R & D domain of Lingzhi triterpenoids, Shuang Hor Group has invested almost a king’s ransom in procuring the purification instruments and facilities essentially needed to produce high purity health-care products for the benefits of the masses. Through the synergy of hardware and software complementation, we arrived at the conclusion that large scale production of Lingzhi triterpenoids was feasible. In the year 2008, we succeeded in purifying triterpenoids, with the content of up to 9 types of ganoderic acids purified to a level of exceeding 50%. In the following year, the pilot project became a success along with technological transfer to Yung Kien Factory for mass production. We also went on to apply for a patent right for the production process, with the objective of making Shuang Hor Group the only legitimate business entity to produce and market Yung Kien Ganoderma 2. This patent right application is entitled “Ganoderma Extract with High Amounts of Ganoderic (Lucideric) Acids and Method for Producing the Same”.
“As far as the raw material or ingredient is concerned, Yung Kien Ganoderma 2 is basically the same as its predecessor Yung Kien Ganoderma. But the two differ in one aspect, namely the fruiting bodies for the former have to be cultivated in a computerized high-tech greenhouse. These triterpenoids are subject to stringent screening to ensure that the composition gives a rich content of ganoderic acids before they qualify as a raw ingredient for production. The processing involves the incorporation of purified ganoderic acids into the first generation of Yung Kien Ganoderma.

School of Chinese Medicine
A polysaccharide named GSP-2 with a molecular size of 32 kDa was isolated from the fruiting bodies of Ganoderma sinense. Its structure was well elucidated, by a combined utilization of chemical and spectroscopic techniques, to be a β-glucan with a backbone of (1→4)– and (1→6)–Glcp, bearing terminal- and (1→3)–Glcp side-chains at O-3 position of (1→6)–Glcp. Immunological assay exhibited that GSP-2 significantly induced the proliferation of BALB/c mice splenocytes with target on only B cells, and enhanced the production of several cytokines in human peripheral blood mononuclear cells and derived dendritic cells. Besides, the fluorescent labeled GSP-2 was phagocytosed by the RAW 264.7 cells and induced the nitric oxide secretion from the cells.
Public Library of Science
First Page (page number)
Han, Xiao-Qiang, Gar-Lee Yue, Cai-Xia Dong, Chung-Lap Chan, Chun-Hay Ko, Wing-Shing Cheung, Ke-Wang Luo, Hui Dai, Chun-Kwok Wong, Ping-Chung Leung, and Quan-Bin Han. "Structure elucidation and immunomodulatory activity of a beta glucan from the fruiting bodies of Ganoderma sinense." PLoS ONE 9.7 (2014): e100380.

The polysaccharides from Tremella reduced oxidative stress and cell apoptosis in the treated skin. It also protected the skin fibroblasts from oxidative stress. (Shen, Gusman) Oxidative stress is one main reason our skin becomes wrinkled as we age, so using these polysaccharides topically could be beneficial in protecting our skin from wrinkles. The Polysaccharides, which make up about 90% of this species of mushroom, also assist the skin in its ability to retain moisture, an ability that decreases as we age. Tremella polysaccharides have also been researched for lightening skin spots in sun damaged skin and have been shown to inhibit melanin formation. Another study explored Ganoderma polysaccharides and determined that these compounds protect against “photo-aging” by eliminating UVB-induced reactive oxygen species. (Zeng 2016). One local Ganoderma to the PNW is Ganoderm oregonense, an analog to the Ganoderma Tsugae of the Eastern states. In one study, lanostane terpenoids extracted from Ganoderma tsugae fruiting bodies protected human keritinocytes from photodamage. (Lin 2013)
Triterpenoids and Polysaccharides for Atopic Dermatitis
Atopic dermatitis is a type 1 hypersensitivity reaction, which means it is an IgE mediated immediate hypersensitivity reaction, like an immediate allergic response. Researches explored a beta-glucan based cream for mild to moderate atopic dermatitis. Topical application resulted in significant improvement. In this study, the people with dermatitis put the cream on half their body, and nothing on the other half. The half of their body that the cream was applied to showed significant decline in dermatitis. (Jesenak 2015) This benefit would come from the water soluble constituents of the mushrooms, while another study looked at the lipophilic triterpenes for type 1 hypersensitivity reactions. They found that the triterpene extract inhibited histamine release from rat mast cells induced by IgE. (Rios 2010) This is a great example where a cream made from both the water and oil extract of the mushroom could be extremely beneficial for these skin conditions. Another example of a type 1 hypersensitivity reaction is the inflammation and itch that we get in response to mosquito bites.

Thereafter, 20 μL of spore solution were added to each well, except to the broth sterility control wells. Micro plates were incubated at 25°C for at least 48 h. Then the wells were checked for fungal growth using a stereo microscope. A subsequent protein staining of the plates with Coomassie Blue G250 was carried out as described by (Troskie et al. 2012) to allow discrimination between fungal biomass and precipitates of fruit body extracts.
Candida krusei micro plates were prepared based on the layout and protocol for filamentous fungi. However only liquid PDB was used, and micro plates were shaken periodically (for 5” every 30’) to avoid on-surface growth.
Hosts, isolation, and cultivation of fungal strains
In sum, nineteen fungal strains were isolated for this study: five strains of F. fomentarius, 11 strains of F. pinicola, and three strains of P. betulinus. Strains were isolated from a narrow geographical area spanning a maximum of hundred kilometres, with a few control strains isolated form the southern side of the Alps, and one strain from the mediterranean area. F. fomentarius was isolated from Fagus sylvatica, Picea abies and Quercus pubescens; F. pinicola was isolated from Abies alba, Alnus incana, Larix decidua and P. abies. P. betulinus was isolated from Betula pubescens only.
HPLC analysis of fruit body extracts
High-performance liquid chromatography (HPLC) of fruit body extracts showed that polypore strains differ in both, qualitative and quantitative secondary metabolite production. F. fomentarius strain IB20130019 was significantly different by showing an extremely poor production of secondary metabolites. F. pinicola strains showed a very high variation in the quantity of secondary metabolites produced (Additional file 1: Figure S1).

Some of them are found everywhere, others grow in certain countries.
Sometimes groups of mushrooms grow in the forests in the form of a circle, which is popularly called the “witch’s circle”. Previously, many associated this phenomenon with magic. Science, however, provided a logical explanation for this phenomenon. Sometimes the mycelium grows equally quickly in all directions. When the main fungus growing in the center dies, new ones grow along the edges of the mycelium, forming a circle and absorbing all nutrient compounds from the soil. As a result of this, it is formed, as it were, trampled underfoot by someone (and in the Middle Ages there was no doubt that there was no witch) in a place inaccessible to people, a circle with mushrooms growing along its edges (like an arena barrier).
Ganoderma, maytake (Curly griffin) or mutton mushroom, Kombucha possess therapeutic properties. In oncology, red camphor mushroom is widely used, which is also called camphor anthrody. It grows in Taiwan and is the property of the country. It contains substances that eliminate tumors. It not only helps fight cancer, but also eliminates toxins.
Of interest to doctors is the exotic species of iiitake (Japanese mushroom). It can be grown in the garden or in the greenhouse. Japanese and Chinese doctors have long been aware of its healing properties. At home it is called the "elixir of youth" and is used to treat various diseases.
Muer black mushrooms growing on trees are also popular in the modern world. They are rarely found in Russia. Dried black fruit bodies are like charred paper. Their use in cooking does not differ from the preparation of forest mushrooms. Black mushrooms taste like seafood.
Red Book Mushrooms
In the Red Book listed hedgehog comb (grandfather's beard). The mushroom body consists of many thin and long processes hanging down. Shaggy hats grow on trees, they are painted white. After heat treatment, the dishes have a chicken flavor. This is not the only protected species.

Ganoderma-Aloe Cream 100 ml
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Ganoderma-Aloe Cream 100 Ml
The Ganoderma Lucidum or Reishi, an ancient Asian fungus, considered as the eternal youth, has active ingredients which act on various organs, including the skin, providing minerals, antioxidant and vitamins with rejuvenating, anti-stress, oxygenating and revitalizing actions. Its combination with Aloe Vera and Argan and Rosehip oils gives the epidermis the desired beauty and youthfulness.
Mode of use: Apply Ganoderma-Cream in the morning and/or evening on face and neck with a gentle massage until completely absorbed. For best results, we recommend apply first the Ganoderma Essence.

- Ganoderma RG & GL
- Ganoderma RG & GL
Our founder, Dr. Lim Siow Jin, has spent more than a decade in the research and development of mushroom cultivation technology. Through this R&D, he has developed a special technology that is capable of producing a 100% yield of high-quality mushroom. Furthermore, of the 3,000-plus mushroom species known, 2,000 are edible and 200 have therapeutic effects, and only six of them have the highest quality. Our special cultivation technology have consistently produced these six species, namely, Kimshen Gano, Peacock Gano, Heart Gano, Liver Gano, Brain Gano and Ruyi Gano. These facts account for the consistent and superior efficacy of our RG/GL.
By consuming Ganoderma regularly, the natural immune system of the body gets regulated and becomes effective. This prevents infectious diseases and toxin accumulation in the body. Though one appears healthy today, there are chances of being attacked by dormant diseases in the body at a later date, when the natural immune system fails. Ganoderma also balances the bio chemistry and stabilizes all functions of the body. Therefore, Ganoderma is advised to a Healthy person as a PREVENTIVE system. A maintenance dosage of 1 – 2 pairs of RG/GL is recommended throughout life.
No. Never. Ganoderma is NOT a replacement or substitute for Medicine. Ganoderma should be consumed along with the medications as a food supplement only. Medications should always be taken as per the advice of one’s own physician. In actual experience, health improves due to the consumption of Ganoderma and therefore the dependence on medications come down.
Toxins may originate from internal and external causes. They can be produced as metabolic and body waste internally, or originated from external sources like polluted air, smoke, food, water and various micro-organisms that we may come in close contact with. Our daily food may contain additives like preservatives, antibiotics, flavoring and coloring agents, stabilizers, and other chemicals used in agriculture.
Ganoderma does not lead to any side-effects, whatsoever. There will be a phase of detoxification in the body, for a few days, within the first 30 weeks. During this time body discharges all the toxins and the body is cleansed.

Gourmet Mushrooms, Inc. has pioneered specialty mushroom cultivation for almost 30 years and is considered a world leader in this field. Based on the research of Dr. Tsuneto Yoshii of Japan and the continuing close relationship, GMI was first to commercially cultivate Shiitake in the Western Hemisphere, and to develop cultivation of the Pompon Blanc™ (Pom Pom) Mushroom. The company supplies the finest chefs in North America.
Along with fresh cultivated mushrooms, GMI has a selection of seasonal wild mushrooms, truffle oils, dried mushrooms (including Morels, Black Trumpet, Shiitake and Porcini) and nutraceuticals. Since its inception, the company has produced a line of mushroom mycelial biomass products for the nutraceutical industry. The mushroom nutraceutical products are marketed worldwide.

Turkey tails also are known as trametes versicolor, coriolus versicolor, polyporus versicolor, yun zhi, and kawartake.
The polysaccharides kresin and peptide in turkey tail offer cancer-fighting properties. Studies also found that a daily dose of turkey tail improved the immune function in women with breast cancer.
Turkey tail has krestin and polysaccharide peptide to boost immunity and suppress inflammation.
In a study of patients with gum disease, patients who received turkey tail and reishi mushrooms showed positive results.
The prebiotics in turkey tail help grow good bacteria such as bifidobacterium and lactobacillus while limiting bad bacteria like staphylococcus and clostridium.
Turkey tail mushroom also is used to treat HPV, increase energy, and recover from long-term illnesses.
Unlike many other mushroom species, oyster mushrooms are relatively new, having been cultivated for around 100 years. Nonetheless, they have a higher concentration of antioxidants than any other commercial mushroom. A popular addition to many dishes, the oyster mushroom often is served on its own thanks to its mild taste and anise- or licorice-like flavor. This popular mushroom grows easily and it does not spoil quickly after being harvested, instead maintaining its freshness. In addition to its popularity as a food item, oyster mushrooms are used in the manufacturing of cosmetics, pharmaceuticals, and paper. Not surprisingly, oyster mushrooms rank third in the amount produced.
Oyster mushrooms grow wild in forests causing its host tree to decompose and like the cordyceps, oyster mushrooms are carnivorous, eating parasitic animals on its host tree. They don’t stop there, however, and will eat debris from food to petroleum. As such, they are a great resource for mycorestoration – the use of fungi to restore damaged habitats.
Oyster mushrooms grow in a range of colors including white, tan, yellow, brown and pink, and are also known as Pleurotus ostreatus, tree oyster, oyster shelf, straw mushroom, and tamogitaki, and hiratake.
Tests on human cells found that oyster mushroom extract may help to suppress breast and colon cancer. In-vivo tests also revealed therapeutic effects in fighting colorectal tumors and leukemia cells. An isolated lentin showed anti-tumor activity in mice.

It’s that season again, and although the going rate is not profitable, the mushroom man can’t resist a hike in the woods to uncover a burried treasure. Chanterelles are on the left, matustakes on the right.
“The Matsutake grow under trees and are usually concealed under fallen leaves and/or the duff layer. It forms a symbiotic relationship with the roots of a limited number of tree species. In Japan it is most commonly associated with Japanese Red Pine. However in the Pacific Northwest it is found in coniferous forests made up of one or more of the following: Douglas Fir, Noble Fir, Shasta Fir, Sugar Pine, Ponderosa Pine and Lodge Pole Pine. Further south, it is also associated with hardwoods, namely Tanoak and Madrone forests. The Pacific Northwest and other similar temperate regions along the Pacific Rim also hold great habitat producing these and other quality wild mushrooms.
- C. subalbidus: In California and the Pacific Northwest of USA there is also the White chanterelle, which looks like the golden chanterelle except for its off-white color. It is more fragile and found in lesser numbers than the golden chanterelle, but can otherwise be treated as its yellow cousin.
- C. formosus: The Pacific golden chanterelle (C. formosus) has recently been recognized as a separate species from the golden chanterelle. It forms a mycorrhizal association with the Douglas-fir and Sitka spruce forests of the Pacific Northwest. This chanterelle has been designated Oregon‘s state mushroom, due to its economic value and abundance.” (Wiki)

Another friend has had a pretty serious skin discoloration for over 25 years and now since taking these products his skin is beginning to even out to one skin tone. Many individuals I know have reported improvements in digestion and bowel movements, while others are reporting being able to move with ease without joint pains and getting restful quality sleep at nights.
Research and Case Studies
- Reishi mushroom (Ganoderma lucidum) - Integrative Practitioner
Reishi mushroom (Ganoderma lucidum), or as the Chinese call it ling zhi, grows wild on decaying logs and tree stumps. Reishi occurs in six different colors, and can be found
- Ganoderma Information on Healthline
There have been many case studies performed on the the fungus Ganoderma lucidum. This article on Healthline talks about studies done in Taiwan and Columbia University
- case studies on ganoderma - Google Scholar
Here's a link to the Google Scholar where one can find numerous case studies that have been performed on ganoderma in pdf form with scientific language and conclusions,
More Reishi or Ling Zhi Products to Try
About Organo Gold and Recap of the Reishi Mushroom
As we grow older, while living longer in today's society, it becomes important to develop a healthy lifestyle that will assist in having a fuller productive life free for illness whenever possible. While the side effects mentioned sound irritating and uncomfortable; they are usually temporary and minor. Keep in mind that many alternative/natural products work to cleanse and eliminate toxins during the overall healing process. For my family and me, it has become important to make small lifestyle changes such as using alternative and natural medicines or TCM instead of prescription drugs whenever possible.
Now-a-days prescription drugs in my opinion may assist in smoothing over one ailment only to cause some times a more severe ailment to occur. The more I research, the more I'm learning the importance of honoring one's body by providing it with foods and herbs from nature as much as possible in order to create balance.

Bio Reishi / Ling Zhi
Glossy Ganoderma extract
, Reishi, in China Ling Zhi or 'mushroom of immortality' in traditional Chinese medicine to be very successful, since about 4000 years, with used. More and more attention to the Reishi is now also in Europe.
You will find him with us in the wild, however, rather rare. Because of its particularly shiny cap may also be known as Ganoderma. The taste of Reishi is rather bitter and is, therefore, as a pure edible mushroom rather unsuitable.
Its application range is very wide.
The Reishi medicinal mushroom contains vitamins and minerals, including iron, Magnesium, calcium, zinc, copper, manganese and Germanium. Important polysaccharides and triterpenes are also here.
The Reishi medicinal mushroom can be used for about 20 years, organically and strictly controlled planted and is now affordable for everyone. Available of Ling-Zhi in dried Form, powder or extracts of the red Ling Zhi is the most high quality.
Our organic medicinal mushrooms are vegan, processed in Germany without the help of artificial additives and are also tested for heavy metals and pesticides.
Through the gentle drying of the whole fruit body, and the pulverization at a very low temperature, you get very good quality.
Mushroom extracts are up to 20 times more effective than “only” mushroom powder!

Iteng Jun of Mie University in Japan conducted an anti-tumor experiment on Brazilian mushroom (Agaricus blazei) and found that the amount of Brazilian mushrooms was about 90% effective in killing cancer cells and prevented their proliferation ability to be 99.4%. Both are higher than Ganoderma lucidum, which means that Brazilian mushrooms (Agaricus blazei) are 4-5 times higher than Ganoderma lucidum regardless of quality and efficacy. (Please refer to the comparison of the anti-cancer effects of Brazilian mushroom (Agaricus blazei) and other tang ganoderma lucidum). So it is also called by the world medical community "the last food for cancer patients on Earth.
Comparison of Anticancer Effects of Brazilian Mushroom (Agaricus blazei) and Other Fungi
Name of Mushroom
Daily Dosage (mg)
Total Recovery Rate
(The monkey bench, wood fungus)
(Hu Sun Eye, Bovine Liver)
(Pearl mushroom, slip mushroom)
Brazilian mushroom β-D-glucan super-human immune supplement
β-D glucan can activate macrophages, neutrophils, etc., thereby increasing the content of leukocyte, cytokinin, and special antibodies, and fully stimulating the body's immune system. A large number of experiments have shown that β-D glucan can promote the production of IgM antibodies in vivo to improve the humoral immunity. In addition, β-D glucan is widely used in pharmaceuticals, foods, and foods, because it has free radicals, anti-radiation, and cholesterol solubilization, prevents hyperlipidemia and protects against infections caused by viral infections, fungi, and bacteria. Other industries. Recent studies have found that β-D glucan can be used as a genetic material that plays a central role in life activities. It can control cell division and differentiation, regulate cell growth, and treat cancer, hepatitis, cardiovascular disease, diabetes, and lipid-lowering, anti-aging, etc. There are unique biological activities. At present, all countries in the world, especially in Japan, the United States, Russia and other countries, β-D dextran has been widely used in food and health care, beauty and skin care industries.
Brazilian mushroom β-D glucan features:
1. Excellent immune activator
2. Strong free radical scavenger
3. Activates macrophages, neutrophils, etc.

- About Reishi
A Brief History of Reishi
The origins of Reishi can be traced back over 4,000 years. Found in ancient Chinese Medicinal Books, it is ranked number 1, above all other herbs. It is from earning this high position that it is often called “the King of Herbs” and “The Mushroom of Immortality”. Though early information is sparse, it is believed that it was highly sought after by ancient Chinese emperors because of its reputation for effectiveness. Due to it's rarity in nature, they tried to keep the mushroom's benefits as secret as possible. It is written that punishments were given to royal court doctors who spoke of Antler-shaped Reishi's medicinal value!
What is Reishi?
In simplest terms, Reishi, or Ganoderma Lucidum, is a rare type of mushroom, which belongs to the family of herbs. Known by several names, in Chinese it’s often referred to as Ling Chih or Ling Zhih. It’s extremely rare, and in order to produce enough to meet the demands of all people, it must be cultivated and scientifically processed. Very few companies in the world have the technology, equipment, or resources to do this properly, so finding the best Reishi is essential to achieve all the potential health benefits it can offer.
Among Reishis, there are six different types, identified by their color. Among them, Red Reishi offers the most health benefits. Red Reishis in general are quite rare, and among Red Reishis, there is one that is far more effective than all of them. This very special Reishi is called “Antler-shaped, so named because it’s shape resembles deer antlers. But Antler-shaped Reishi is also extremely rare, since it is estimated that only 1 in 100,000 Red Reishis found in the wild will be Antler-shaped. This is one reason why Antler-shaped Reishi must be cultivated using highly specialized processes. While most manufacturers find that producing Antler-shaped Reishi is too cost-prohibitive, Genius Legendary’s massive volume allows us to produce this very desirable Reishi at economical prices. In addition, Genius Antler-shaped Reishi is 500% concentrated, 100% organically grown, and 100% pure, which makes ours the world’s best Reishi!
Who can benefit?

Differences Between True And False Shiitakes
An irregular/bent shape
Wavy and lobed
Freely hanging from the stem
When you slice it, a false morel isn't hollow and filled with cotton like fibers inside.
Smooth uniform shape
Light-dark brown color
Covered in pits and ridges
Directly attached to the stem
Once you slice your shiitake, it should be hollow from the bottom of the stem to tip of the cap
History Of Shiitake Mushrooms As Medicine
Shiitake mushrooms helped people in Medieval Asia to prevent common colds, fight hunger, and boost energy levels (link). In East Asia, Shiitake Mushrooms were a delicacy preserved for royalty because of their benefits, taste, and cost.
They mostly grew in East Asia, particularly Japan, China, Korea, and Taiwan. Farming of shiitake mushrooms spread to other regions in the 1970s like USA, Singapore, and parts of Europe because of their nutritional and medicinal benefits and commercial viability.
How To Use Shiitake Mushrooms As Medicine
Shiitake mushrooms contain high fat, protein, carbohydrate, mineral, and vitamin content. Some of the medicinal and therapeutic benefits include:
Antitumor Properties - Can prevent and inhibit the growth and formation of tumors (link).
Antimicrobial Properties - May inhibits the growth and reproduction of microorganisms (link).
Antibacterial Properties - Shown to interfere with the growth and reproduction of bacteria (link).
Antiviral Properties - Could help in the prevention and treatment of viral infections (link).
Immunomodulation Capabilities - Helps in the alteration of the immune system into desired levels (link).
Cardiovascular Health Properties - Helps in maintaining sound heart health (link).
Hepatoprotective Properties - Could prevent liver damage (link).
Hemagglutination Capabilities - Could prevent the clumping of red blood cell particles (link).
Shiitake Dosage - The appropriate dosage of shiitake for you depends on a number of factors like your age, health, and allergies. No tangible evidence indicates the right dosage.
Pharmacists advise users to take it according to the directions on the product and consult your physician before use.
Side Effects of Shiitakes - The information about the side effects of consuming shiitake medicine remains scarce.

As mentioned above, Purple Reishi has a lower overall volume of triterpenes than its red counterpart, yet there have still been a number of unique, biologically active terpenoids discovered in the fruiting body since 2007. Ganoderic Acid Jc for example, showed inhibitory activity against acute myeloid leukaemia cell lines in vitro.
The effect that Purple Reishi polysaccharide compounds can have on regulating inflammation will also contribute towards its long held reputation as being supportive to the bones, joints and connective tissue.
An in vivo study published in 1998 by F Wan et al, showed that G. sinense had pronounced anti-inflammatory and analgesic effects in cases of rheumatoid arthritis as well as reducing related edema, with no noticeable side effects.
The protective and regenerative effects Purple Reishi could offer to the liver were a common reason for prescribing it throughout the ages, according to traditional Chinese medicine. Scientifically speaking, it is often believed that the triterpenes from Red Reishi are primarily responsible for the many advantages to the liver, and Purple Reishi contains only a limited number of triterpenes in comparison.
There are of course many contributing factors towards the ‘entourage effect’ of this medicine – a phenomenon that can be observed through scientific methods, but not yet clearly understood or easily delineated. While the precise mechanisms of action regarding the liver remain unclear, a novel triterpene called Ganolucidate F was discovered in 2011 and was able to regulate the activity of Cytochrome P450 – a liver enzyme responsible for the metabolism of toxins and drugs and their safe detoxification from the body.
Purple Reishi Products
Like the wild mushroom itself, high quality Purple Reishi products are few and far between. As with Red Reishi it is the fruiting body that offers the most complete source of medicine. The most common form Purple Reishi is found in, is either whole dried fruiting bodies or slices of the fruiting bodies. Traditionally these are used to decoct into a tea, added to soups and broths (and removed prior to consumption) or macerated/slow cooked in wine. Pure grade extract powders are not yet available, although some manufacturers are selling liquid extracts of the fruiting body.

Interest in Phellinus linteus was renewed after World War II when it was used to treat victims of the Nagasaki and Hiroshima bombing victims. Continued research led to Korean FDA approval in the 1993 for the use and sale of Phellinus linteus as an anti-tumor medicine.
Phellinus linteus mushrooms grow primarily on mulberry trees, but also on other closely aligned species mainly in China, Korea, and Japan. It has a dark, hoof-like shape that resembles the bark of the branches and stems on which it grows.
Other names include mesimakobu (Japan), song gen (China), and sang hwang (Korea).
Hispidin, a phenolic compound, along with acid polysaccharides and the polysaccharide-protein complex in Phellinus mushrooms increase immune cell activity, modulate the proliferation of bad cells, and help inhibit tumor growth.
Phellinus linteus mushrooms have two polysaccharide-protein complexes, beta D-glutan and lectin, to help control the immune system.
Phellinus linteus contains the compounds CHCl3, n-BuOH and H2O to fight bacteria.
Cambodian Phellinus linteus was tested to determine its appropriateness as an ingredient in cosmetics and was found to have anti-lipid peroxidation and anti-wrinkle effects.
Exopolysaccharides extracted from Phellinus may ward off autoimmune diabetes though regulation of the cells involved in the immune response. Furopyranone compounds may help treat diabetic complications, and Interfungins can help regulate blood sugar levels.
Phellinus linteus may also help gastroenteric dysfunction, eczema, heart disease, and high blood pressure.
Poria filaments have been used in Chinese medicine for two-thousand years for its healing properties. Due to its sweet taste it is said to target the heart, spleen, lung, and kidney meridians, which affect the body’s spirit and qi (energy). Because is was expensive to produce, it originally was a delicacy reserved for the royal family. Now it is commonly available and widely-used, not only as an alternative medicine but also in many Chinese patent medicines. Known as the “medicine of immortality”, among poria’s traditional functions were to get rid of dampness and disinhibit water for which it is honored as a dampness-eliminating panacea.

Difference Between Algae and Fungi
Algae vs Fungi
When anyone is asked about the difference between the algae and fungi, the quick answer is most likely that algae are the green slimy matter that you can observe at the base of your aquarium or at the bottom of your pool when left non-chlorinated. For fungi, these are the mushrooms that you can readily see at the forest or even at your own backyard. Well, this is probably the simplest visual difference between the two.
Foremost, fungi is the plural form for fungus. There are many types of such like molds, yeasts and the most popular ‘“ mushrooms. Fungi are able to decompose organic matter a lot faster. They literally eat up the available nutrients like in the case of an uneaten fruit that’s left in the open at regular temperature. After quite some time, this fruit will become uneatable because molds start to surround and eat it up. They are ‘decomposers’ that brings something back to earth (changing organic into inorganic).
They are described as both symbiotic and parasitic. They try to feed themselves using the carbon from other organisms. Take note, almost anything are structurally based on carbon: humans, plants, insects, and most animals.
There are some fungi that are known to be edible like the Portobello mushrooms, straw mushrooms and the oyster mushrooms. Blue cheese is also a popular food item that is derived from fungi. Despite this, there are still many fungi that are deemed dangerous for ingestion. As such, you are advised not to eat the mushrooms that you just see somewhere else like in the forest and the woods. Often, these mushrooms are poisonous in nature. Nevertheless, although fungi aren’t classified as animals they are without a doubt still not plants. In fact, they are classified into a big group separate from plants and animals ‘“ Kingdom Fungi.
Algae (singular alga) are different because they are plant-like. This means that they also do the process of photosynthesis because they use light energy for nourishment on top of all the minerals they get from the water surrounding them. Thus, they convert the inorganic into an organic material. In addition, algae are said to be the origin of the primitive plant types. They were the biologic ancestors of many of today’s higher plants. Like fungi, some algae (i.e. seaweeds) are edible.

The premiere tonic herb in Classical Chinese Medicine, Reishi extracts support
immune and liver health.
Hot water extracts contain 25-80 times more polysaccharides than mycelium grown
on rice, liquid alcohol extracts or unextracted mushrooms. Validated by two thousand
years of traditional herbalism, hot water extracts are the only form of mushroom
supplement ever used of studies in scientific research.
One capsule contains:
Organic Reishi ( Ganoderma lucidum, Reishi Gano 161®) 400 mg *
hot water/alcohol extract 14%polysaccharide, 4% triterpene
* Daily Value not established
Vegetarian capsules ( cellulose ), Ganoderma lucidum mycelium,
1-3 capsules twice daily, AM and PM, or more as recommended by your health care
professional. Take on an empty stomach.
*This statement has not been evaluated by the FDA.This product is not intended to
diagnose, treat, cure, or prevent any disease.