text_1: 显著 且 有 临床意义 的 益处 在 随机 分组 后 的 早期 即可 观察 到 , 并且 在 因 心力衰竭 接受 其他 推荐 治疗 的 患者 中 也 可 观察 到 .
  
text_2: the observed benefits , which were substantial and clinically significant , occurred early after randomization and were seen in patients who were receiving other recommended therapies for heart failure .
  