text_1: Smc5/6 engagment halts the activation of SUMO E3 ligase Mms21 by ATP-dependent remolding.
text_2: Our results demonstrate that the ATP-binding activity of the Smc5/6 complex is coordinated with its SUMO ligase, through the coiled coil domain of Smc5 and the physical remodeling of the molecule, to promote sumoylation and chromosome disjunction during DNA repair.