text_1: MFGE8 regulates fat absorption by binding to av-Beta3 and av-Beta5 integrins.
text_2: We show here that Mfge8 promotes the absorption of dietary triglycerides and the cellular uptake of fatty acid and that Mfge8-deficient (Mfge8−/−) mice are protected from diet-induced obesity, steatohepatitis and insulin resistance.