text_1: RANK-RANKL pathway signalling has no known association with development of Aire-expressing medullary thymic epithelial cells.
text_2: Ligation of RANK or CD40 on fetal thymic stroma in vitro induced mTEC development in a tumor necrosis factor-associated factor 6 (TRAF6)-, NF-kappaB inducing kinase (NIK)-, and IkappaB kinase beta (IKKbeta)-dependent manner.