text_1: The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is required for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.
text_2: Together, we have uncovered a highly selective, essential role for an atypical PRC1-family complex in ES cells and early development.