text_1: IFI16 impedes STING phosphorylation and translocation, resulting in reduced activation of STING.
text_2: Here we show that interferon-γ inducible protein 16 (IFI16) cooperates with cGAS during DNA sensing in human keratinocytes, as both cGAS and IFI16 are required for the full activation of an innate immune response to exogenous DNA and DNA viruses.