text_1: MUC1-C activates the NF-κB p65 signaling pathway by interacting with IκB kinase ß.
text_2: These findings indicate that MUC1 is important for physiological activation of IKKβ and that overexpression of MUC1, as found in human cancers, confers sustained induction of the IKKβ–NF-κB p65 pathway.