text_1: 4-PBA treatment raises endoplasmic reticulum stress in response to general endoplasmic reticulum stress markers.
text_2: Stimulation with glucose causes WFS1 translocation from the ER to the plasma membrane, where it forms a complex with adenylyl cyclase 8 (AC8), an essential cAMP-generating enzyme in the β-cell that integrates glucose and GLP-1 signalling.