text_1: Increased conversion of PGE 2 to PPARy ligand 15-ket-PGE 2 causes accumulation of PGE.
text_2: Here we show that colonic epithelial cells and whole lung tissue from Cftr-deficient mice show a defect in peroxisome proliferator-activated receptor-gamma (PPAR-gamma, encoded by Pparg) function that contributes to a pathological program of gene expression.