text_1: The composition of myosin-II isoform switches from the A isoform to the B isoform during hematopoietic differentiation.
text_2: Here, mass spectrometry-calibrated intracellular flow cytometry of human hematopoiesis reveals MIIB to be a major isoform that is strongly polarized in hematopoietic stem cells and progenitors (HSC/Ps) and thereby downregulated in differentiated cells via asymmetric division.