text_1: MUC1-C activates the NF-κB p65 signaling pathway by interacting with IκB kinase ß.
text_2: We show that MUC1 interacts with the high-molecular-weight IκB kinase (IKK) complex in vivo and that the MUC1 cytoplasmic domain binds directly to IKKβ and IKKγ.