text_1: PKG-la does not have a large impact on expression of spinal long term potentiation in PGK-la knockout mice.
text_2: Finally, behavioural analyses in vivo showed marked defects in SNS-PKG-I(-/-) mice in several models of activity-induced nociceptive hypersensitivity, and pharmacological studies identified a clear contribution of PKG-I expressed in spinal terminals of nociceptors.