text_1: Pretreatment with the Arp2/3 inhibitor CK-666 affects lamelliopodia formation.
text_2: However, questions remain regarding the relative contributions of Arp2/3 complex versus other mechanisms of actin filament nucleation to processes such as path finding by neuronal growth cones; this is because of the lack of simple methods to inhibit Arp2/3 complex reversibly in living cells.