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7
10-20% of people with severe mental disorder receive no treatment in low and middle income countries.
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8
25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.
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16
50% of patients exposed to radiation have activated markers of myofibroblasts.
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23
8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.
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29
A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.
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31
A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.
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33
A deficiency of folate decreases blood levels of homocysteine.
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38
A deficiency of vitamin B6 increases blood levels of homocysteine.
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59
APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.
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65
AZT given with ribavirin alleviates anemia.
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83
Adipocytes in major adipose depots descend from cells with a history of Pdgfra expression.
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84
Adult tissue-resident macrophages are maintained independent of circulating monocytes.
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87
Adult tissue-resident macrophages possess a self-renewing capacity.
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97
Alirocumab treatment increases apo(a) fractional clearance rate.
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101
All phenotypes associated with reduced IIS require the gene daf-16.
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102
All six cathelicidins are located on chromosome two.
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103
Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.
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107
Amitriptyline ineffective as a treatment for chronic tension-type headaches.
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110
An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.
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117
Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile
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125
Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.
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131
Aspirin encourages the production of PGE2.
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135
Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.
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136
Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.
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145
Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.
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147
Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.
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150
Autophagy deficiency in the liver protects from insulin resistance.
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151
Autophagy increases in aged organisms.
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158
BRCA 1 mutation carriers' risk of breast and ovarian cancer is not influence by the location of the mutation.
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162
Bariatric surgery has a deleterious impact on mental health.
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170
Bariatric surgery reduces resolution of diabetes.
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188
Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.
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190
Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.
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191
Bronchial responsiveness is higher in the summer than in the winter.
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192
Bronchial responsiveness is the same in the winter and summer seasons.
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193
C-Met is involved in epithelial-mesenchymal transition in tumor cells.
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194
C. elegans germlines lose their immortal character when nuclear RNAi is activated.
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195
C. elegans germlines lose their immortal character when nuclear RNAi is disabled.
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202
CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.
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206
CENP-B inhibits heterochromatin formation
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207
CHEK2 has a significant role in breast cancer
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215
CRY proteins mediate light signal transduction.
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231
Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.
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234
Cell autonomous sex determination in somatic cells does not occur in Passeriformes.
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240
Cellular aging is uncorrelated with an older appearance.
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257
Choice of specialty is not influenced by debt accrued from medical training.
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260
Chronic aerobic exercise alters endothelial function, impairing vasodilating mechanisms mediated by NO.
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270
Colloid exposure causes morbidity.
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271
Colloid exposure has no effect on morbidity.
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273
Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.
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276
Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.
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282
Conformational changes of the CD3 complex enable ITAM phosphorylation.
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284
Consumption of whole fruits reduces the risk of type 2 diabetes.
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288
Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.
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289
Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.
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291
Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.
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297
Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.
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302
Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.
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307
DUSP4 downregulation activates the Ras-ERK pathway
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311
De novo assembly of sequence data has longer contigs than unassembled sequence data.
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318
Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.
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319
Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.
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320
Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.
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321
Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.
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322
Delayed sleep phase disorder is associated with a dominant coding variation the core circadian clock gene CRY1.
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328
Deletion of αvβ8 results in a spontaneous inflammatory phenotype.
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329
Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.
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344
Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.
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348
Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.
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353
Distant CREs are more conserved among species.
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359
During the primary early antibody response activated B cells express high levels of EBI2.
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360
During the primary early antibody response activated B cells express low levels of EBI2.
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373
Electromagnetic interference has no effect on Radio Frequency Identification (RFID) readability and reading distances.
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374
Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.
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387
Esrrb associates with BAF and Mbd3/NURD complexes.
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395
Excess nitric oxide is responsible for vasospasm.
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402
Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.
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408
Falsified artemisinin family drugs with no active ingredient are generally safe.
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409
Falsified artemisinin family drugs with no active ingredient can be life-threatening.
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412
Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.
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419
Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.
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424
For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.
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433
Foxp3 displaces Foxo1 on chromatin
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438
Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.
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442
G-CSF prevents MDSCs from infiltrating tumors.
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446
GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.
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451
Gene expression can be highly variable across genetically identical cells.
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457
Genes regulated by Esrrb transcription factor are unaffected by Mbd3 function.
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459
Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.
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460
Genetic deletion of JAM-A decreases gut permeability.
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462
Genome size differences in rice are explained by LTR retrotransposon expansion.
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464
Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.
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465
Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.
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467
Ginger is hazardous to mechanically ventilated patients, because these patients are susceptible to mucosal lesions and ulcers.
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468
Ginger is safe for mechanically ventilated patients.
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471
Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.
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476
Golli-deficient T-cells are dormant in initial clonal expansion.
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477
Golli-deficient T-cells are hyper proliferative in initial clonal expansion.
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496
Having a main partner increases survival rates in HIV patients.
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497
Having a main partner lowers survival rates in HIV patients.
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