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CCAgT.py
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| 1 |
+
import json
|
| 2 |
+
import os
|
| 3 |
+
from collections import OrderedDict, defaultdict
|
| 4 |
+
from math import ceil
|
| 5 |
+
|
| 6 |
+
import numpy as np
|
| 7 |
+
import pandas as pd
|
| 8 |
+
|
| 9 |
+
import datasets
|
| 10 |
+
|
| 11 |
+
|
| 12 |
+
logger = datasets.logging.get_logger(__name__)
|
| 13 |
+
|
| 14 |
+
CCAGT_CLASSES = OrderedDict(
|
| 15 |
+
{
|
| 16 |
+
1: "NUCLEUS",
|
| 17 |
+
2: "CLUSTER",
|
| 18 |
+
3: "SATELLITE",
|
| 19 |
+
4: "NUCLEUS_OUT_OF_FOCUS",
|
| 20 |
+
5: "OVERLAPPED_NUCLEI",
|
| 21 |
+
6: "NON_VIABLE_NUCLEUS",
|
| 22 |
+
7: "LEUKOCYTE_NUCLEUS",
|
| 23 |
+
}
|
| 24 |
+
)
|
| 25 |
+
|
| 26 |
+
_LICENSE = "CC BY NC 3.0 License"
|
| 27 |
+
|
| 28 |
+
_CITATION = """\
|
| 29 |
+
@misc{CCAgTDataset,
|
| 30 |
+
doi = {10.17632/WG4BPM33HJ.2},
|
| 31 |
+
url = {https://data.mendeley.com/datasets/wg4bpm33hj/2},
|
| 32 |
+
author = {Jo{\\~{a}}o Gustavo Atkinson Amorim and Andr{\'{e}} Vict{\'{o}}ria Matias and Tainee Bottamedi and Vinícius Sanches and Ane Francyne Costa and Fabiana Botelho De Miranda Onofre and Alexandre Sherlley Casimiro Onofre and Aldo von Wangenheim},
|
| 33 |
+
title = {CCAgT: Images of Cervical Cells with AgNOR Stain Technique},
|
| 34 |
+
publisher = {Mendeley},
|
| 35 |
+
year = {2022},
|
| 36 |
+
copyright = {Attribution-NonCommercial 3.0 Unported}
|
| 37 |
+
}
|
| 38 |
+
"""
|
| 39 |
+
|
| 40 |
+
_HOMEPAGE = "https://data.mendeley.com/datasets/wg4bpm33hj"
|
| 41 |
+
|
| 42 |
+
_DESCRIPTION = """\
|
| 43 |
+
The CCAgT (Images of Cervical Cells with AgNOR Stain Technique) dataset contains 9339 images (1600x1200 resolution where each pixel is 0.111µmX0.111µm) from 15 different slides stained using the AgNOR technique.
|
| 44 |
+
Each image has at least one label. In total, this dataset has more than 63K instances of annotated object.
|
| 45 |
+
The images are from the patients of the Gynecology and Colonoscopy Outpatient Clinic of the Polydoro Ernani de São Thiago University Hospital of the Universidade Federal de Santa Catarina (HU-UFSC).
|
| 46 |
+
"""
|
| 47 |
+
|
| 48 |
+
_DATA_URL = "https://md-datasets-cache-zipfiles-prod.s3.eu-west-1.amazonaws.com/wg4bpm33hj-2.zip"
|
| 49 |
+
|
| 50 |
+
|
| 51 |
+
def tvt(ids, tvt_size, seed=1609):
|
| 52 |
+
"""From a list of indexes/ids (int) will generate the train-validation-test data.
|
| 53 |
+
|
| 54 |
+
Based on `github.com/scikit-learn/scikit-learn/blob/37ac6788c9504ee409b75e5e24ff7d86c90c2ffb/sklearn/model_selection/_split.py#L2321`
|
| 55 |
+
"""
|
| 56 |
+
n_samples = len(ids)
|
| 57 |
+
|
| 58 |
+
qtd = {
|
| 59 |
+
"valid": ceil(n_samples * tvt_size[1]),
|
| 60 |
+
"test": ceil(n_samples * tvt_size[2]),
|
| 61 |
+
}
|
| 62 |
+
qtd["train"] = int(n_samples - qtd["valid"] - qtd["test"])
|
| 63 |
+
|
| 64 |
+
rng = np.random.RandomState(seed)
|
| 65 |
+
permutatation = rng.permutation(ids)
|
| 66 |
+
|
| 67 |
+
out = {
|
| 68 |
+
"train": set(permutatation[: qtd["train"]]),
|
| 69 |
+
"valid": set(permutatation[qtd["train"] : qtd["train"] + qtd["valid"]]),
|
| 70 |
+
"test": set(permutatation[qtd["train"] + qtd["valid"] :]),
|
| 71 |
+
}
|
| 72 |
+
|
| 73 |
+
return out["train"], out["valid"], out["test"]
|
| 74 |
+
|
| 75 |
+
|
| 76 |
+
def annotations_per_image(df):
|
| 77 |
+
"""
|
| 78 |
+
based on: https://github.com/johnnv1/CCAgT-utils/blob/54ade78e4ddb2e2ed9507b8a1633940897767cac/CCAgT_utils/describe.py#L152
|
| 79 |
+
"""
|
| 80 |
+
df_describe_images = df.groupby(["image_id", "category_id"]).size().reset_index().rename(columns={0: "count"})
|
| 81 |
+
df_describe_images = df_describe_images.pivot(columns=["category_id"], index="image_id")
|
| 82 |
+
df_describe_images = df_describe_images.rename(CCAGT_CLASSES, axis=1)
|
| 83 |
+
df_describe_images["qtd_annotations"] = df_describe_images.sum(axis=1)
|
| 84 |
+
df_describe_images = df_describe_images.fillna(0)
|
| 85 |
+
df_describe_images["NORs"] = (
|
| 86 |
+
df_describe_images[
|
| 87 |
+
"count",
|
| 88 |
+
CCAGT_CLASSES[2],
|
| 89 |
+
]
|
| 90 |
+
+ df_describe_images[
|
| 91 |
+
"count",
|
| 92 |
+
CCAGT_CLASSES[3],
|
| 93 |
+
]
|
| 94 |
+
)
|
| 95 |
+
|
| 96 |
+
return df_describe_images
|
| 97 |
+
|
| 98 |
+
|
| 99 |
+
def tvt_by_nors(df, tvt_size=(0.7, 0.15, 0.15), **kwargs):
|
| 100 |
+
"""This will split the CCAgT annotations based on the number of NORs
|
| 101 |
+
into each image. With a silly separation, first will split
|
| 102 |
+
between each fold images with one or less NORs, after will split
|
| 103 |
+
images with the amount of NORs is between 2 and 7, and at least will
|
| 104 |
+
split images that have more than 7 NORs.
|
| 105 |
+
|
| 106 |
+
based on `https://github.com/johnnv1/CCAgT-utils/blob/54ade78e4ddb2e2ed9507b8a1633940897767cac/CCAgT_utils/split.py#L64`
|
| 107 |
+
"""
|
| 108 |
+
if sum(tvt_size) != 1:
|
| 109 |
+
raise ValueError("The sum of `tvt_size` need to be equal to 1!")
|
| 110 |
+
|
| 111 |
+
df_describe_imgs = annotations_per_image(df)
|
| 112 |
+
|
| 113 |
+
img_ids = {}
|
| 114 |
+
img_ids["low_nors"] = df_describe_imgs.loc[(df_describe_imgs["NORs"] < 2)].index
|
| 115 |
+
img_ids["medium_nors"] = df_describe_imgs[(df_describe_imgs["NORs"] >= 2) * (df_describe_imgs["NORs"] <= 7)].index
|
| 116 |
+
img_ids["high_nors"] = df_describe_imgs[(df_describe_imgs["NORs"] > 7)].index
|
| 117 |
+
|
| 118 |
+
train_ids = set({})
|
| 119 |
+
valid_ids = set({})
|
| 120 |
+
test_ids = set({})
|
| 121 |
+
|
| 122 |
+
for k, ids in img_ids.items():
|
| 123 |
+
logger.info(f"Splitting {len(ids)} images with {k} quantity...")
|
| 124 |
+
if len(ids) == 0:
|
| 125 |
+
continue
|
| 126 |
+
_train, _valid, _test = tvt(ids, tvt_size, **kwargs)
|
| 127 |
+
logger.info(f">T: {len(_train)} V: {len(_valid)} T: {len(_test)}")
|
| 128 |
+
train_ids = train_ids.union(_train)
|
| 129 |
+
valid_ids = valid_ids.union(_valid)
|
| 130 |
+
test_ids = test_ids.union(_test)
|
| 131 |
+
|
| 132 |
+
return train_ids, valid_ids, test_ids
|
| 133 |
+
|
| 134 |
+
|
| 135 |
+
def get_basename(path):
|
| 136 |
+
return os.path.splitext(os.path.basename(path))[0]
|
| 137 |
+
|
| 138 |
+
|
| 139 |
+
def get_slide_id(path):
|
| 140 |
+
bn = get_basename(path)
|
| 141 |
+
slide_id = bn.split("_")[0]
|
| 142 |
+
return slide_id
|
| 143 |
+
|
| 144 |
+
|
| 145 |
+
class CCAgTConfig(datasets.BuilderConfig):
|
| 146 |
+
"""BuilderConfig for CCAgT."""
|
| 147 |
+
|
| 148 |
+
seed = 1609
|
| 149 |
+
tvt_size = (0.7, 0.15, 0.15)
|
| 150 |
+
|
| 151 |
+
|
| 152 |
+
class CCAgT(datasets.GeneratorBasedBuilder):
|
| 153 |
+
"""Images of Cervical Cells with AgNOR Stain Technique (CCAgT) dataset"""
|
| 154 |
+
|
| 155 |
+
test_dummy_data = False
|
| 156 |
+
|
| 157 |
+
VERSION = datasets.Version("2.0.0")
|
| 158 |
+
|
| 159 |
+
BUILDER_CONFIG_CLASS = CCAgTConfig
|
| 160 |
+
BUILDER_CONFIGS = [
|
| 161 |
+
CCAgTConfig(name="semantic_segmentation", version=VERSION, description="The semantic segmentation variant."),
|
| 162 |
+
CCAgTConfig(name="object_detection", version=VERSION, description="The object detection variant."),
|
| 163 |
+
CCAgTConfig(name="instance_segmentation", version=VERSION, description="The instance segmentation variant."),
|
| 164 |
+
]
|
| 165 |
+
|
| 166 |
+
DEFAULT_CONFIG_NAME = "semantic_segmentation"
|
| 167 |
+
|
| 168 |
+
def _info(self):
|
| 169 |
+
assert len(CCAGT_CLASSES) == 7
|
| 170 |
+
|
| 171 |
+
if self.config.name == "semantic_segmentation":
|
| 172 |
+
features = datasets.Features(
|
| 173 |
+
{
|
| 174 |
+
"image": datasets.Image(),
|
| 175 |
+
"annotation": datasets.Image(),
|
| 176 |
+
}
|
| 177 |
+
)
|
| 178 |
+
elif self.config.name == "object_detection":
|
| 179 |
+
features = datasets.Features(
|
| 180 |
+
{
|
| 181 |
+
"image": datasets.Image(),
|
| 182 |
+
"objects": datasets.Sequence(
|
| 183 |
+
{
|
| 184 |
+
"bbox": datasets.Sequence(datasets.Value("float32"), length=4),
|
| 185 |
+
"label": datasets.ClassLabel(names=list(CCAGT_CLASSES.values())),
|
| 186 |
+
}
|
| 187 |
+
),
|
| 188 |
+
}
|
| 189 |
+
)
|
| 190 |
+
elif self.config.name == "instance_segmentation":
|
| 191 |
+
features = datasets.Features(
|
| 192 |
+
{
|
| 193 |
+
"image": datasets.Image(),
|
| 194 |
+
"objects": datasets.Sequence(
|
| 195 |
+
{
|
| 196 |
+
"bbox": datasets.Sequence(datasets.Value("float32"), length=4),
|
| 197 |
+
"segment": datasets.Sequence(datasets.Sequence(datasets.Value("float32"))),
|
| 198 |
+
"label": datasets.ClassLabel(names=list(CCAGT_CLASSES.values())),
|
| 199 |
+
}
|
| 200 |
+
),
|
| 201 |
+
}
|
| 202 |
+
)
|
| 203 |
+
else:
|
| 204 |
+
raise NotImplementedError
|
| 205 |
+
|
| 206 |
+
return datasets.DatasetInfo(
|
| 207 |
+
description=_DESCRIPTION,
|
| 208 |
+
features=features,
|
| 209 |
+
homepage=_HOMEPAGE,
|
| 210 |
+
license=_LICENSE,
|
| 211 |
+
citation=_CITATION,
|
| 212 |
+
)
|
| 213 |
+
|
| 214 |
+
def _download_and_extract_all(self, dl_manager):
|
| 215 |
+
def extracted_by_slide(paths):
|
| 216 |
+
return {get_slide_id(path): dl_manager.extract(path) for path in paths}
|
| 217 |
+
|
| 218 |
+
data_dir = dl_manager.download_and_extract(_DATA_URL)
|
| 219 |
+
base_path = os.path.join(data_dir, "wg4bpm33hj-2")
|
| 220 |
+
|
| 221 |
+
logger.info("Extracting images...")
|
| 222 |
+
self.images_base_dir = os.path.join(base_path, "images")
|
| 223 |
+
images_to_extract = [
|
| 224 |
+
os.path.join(self.images_base_dir, fn) for fn in os.listdir(self.images_base_dir) if fn.endswith(".zip")
|
| 225 |
+
]
|
| 226 |
+
self.images_extracted = extracted_by_slide(images_to_extract)
|
| 227 |
+
|
| 228 |
+
if self.config.name == "semantic_segmentation":
|
| 229 |
+
logger.info("Extracting masks...")
|
| 230 |
+
self.masks_base_dir = os.path.join(base_path, "masks")
|
| 231 |
+
masks_to_extract = [
|
| 232 |
+
os.path.join(self.masks_base_dir, fn) for fn in os.listdir(self.masks_base_dir) if fn.endswith(".zip")
|
| 233 |
+
]
|
| 234 |
+
self.masks_extracted = extracted_by_slide(masks_to_extract)
|
| 235 |
+
elif self.config.name in {"object_detection", "instance_segmentation"}:
|
| 236 |
+
logger.info("Reading COCO OD file...")
|
| 237 |
+
ccagt_OD_COCO_path = os.path.join(base_path, "CCAgT_COCO_OD.json")
|
| 238 |
+
with open(ccagt_OD_COCO_path, "r", encoding="utf-8") as json_file:
|
| 239 |
+
coco_OD = json.load(json_file)
|
| 240 |
+
|
| 241 |
+
self._imageid_to_coco_OD_annotations = defaultdict(list)
|
| 242 |
+
for labels in coco_OD["annotations"]:
|
| 243 |
+
self._imageid_to_coco_OD_annotations[labels["image_id"]].append(labels)
|
| 244 |
+
|
| 245 |
+
logger.info("Loading dataset info...")
|
| 246 |
+
ccagt_raw_path = os.path.join(base_path, "CCAgT.parquet.gzip")
|
| 247 |
+
with open(ccagt_raw_path, "rb") as f:
|
| 248 |
+
self._ccagt_info = pd.read_parquet(f, columns=["image_name", "category_id", "image_id", "slide_id"])
|
| 249 |
+
self._bn_to_imageid = pd.Series(
|
| 250 |
+
self._ccagt_info["image_id"].values, index=self._ccagt_info["image_name"]
|
| 251 |
+
).to_dict()
|
| 252 |
+
|
| 253 |
+
def _split_generators(self, dl_manager):
|
| 254 |
+
"""Returns SplitGenerators."""
|
| 255 |
+
|
| 256 |
+
def build_path(basename, tp="images"):
|
| 257 |
+
slide = basename.split("_")[0]
|
| 258 |
+
if tp == "images":
|
| 259 |
+
dir_path = self.images_extracted[slide]
|
| 260 |
+
ext = ".jpg"
|
| 261 |
+
else:
|
| 262 |
+
dir_path = self.masks_extracted[slide]
|
| 263 |
+
ext = ".png"
|
| 264 |
+
|
| 265 |
+
return os.path.join(dir_path, slide, basename + ext)
|
| 266 |
+
|
| 267 |
+
def images_and_masks(basenames):
|
| 268 |
+
for bn in basenames:
|
| 269 |
+
yield build_path(bn), build_path(bn, "masks")
|
| 270 |
+
|
| 271 |
+
def images_and_boxes(basenames):
|
| 272 |
+
for bn in basenames:
|
| 273 |
+
image_id = self._bn_to_imageid[bn]
|
| 274 |
+
labels = [
|
| 275 |
+
{"bbox": annotation["bbox"], "label": annotation["category_id"] - 1}
|
| 276 |
+
for annotation in self._imageid_to_coco_OD_annotations[image_id]
|
| 277 |
+
]
|
| 278 |
+
|
| 279 |
+
yield build_path(bn), labels
|
| 280 |
+
|
| 281 |
+
def images_and_instances(basenames):
|
| 282 |
+
for bn in basenames:
|
| 283 |
+
image_id = self._bn_to_imageid[bn]
|
| 284 |
+
instances = [
|
| 285 |
+
{
|
| 286 |
+
"bbox": annotation["bbox"],
|
| 287 |
+
"label": annotation["category_id"] - 1,
|
| 288 |
+
"segment": annotation["segmentation"],
|
| 289 |
+
}
|
| 290 |
+
for annotation in self._imageid_to_coco_OD_annotations[image_id]
|
| 291 |
+
]
|
| 292 |
+
|
| 293 |
+
yield build_path(bn), instances
|
| 294 |
+
|
| 295 |
+
self._download_and_extract_all(dl_manager)
|
| 296 |
+
|
| 297 |
+
logger.info("Splitting dataset based on the NORs quantity by image...")
|
| 298 |
+
train_ids, valid_ids, test_ids = tvt_by_nors(
|
| 299 |
+
self._ccagt_info, tvt_size=self.config.tvt_size, seed=self.config.seed
|
| 300 |
+
)
|
| 301 |
+
train_bn_images = self._ccagt_info.loc[self._ccagt_info["image_id"].isin(train_ids), "image_name"].unique()
|
| 302 |
+
valid_bn_images = self._ccagt_info.loc[self._ccagt_info["image_id"].isin(valid_ids), "image_name"].unique()
|
| 303 |
+
test_bn_images = self._ccagt_info.loc[self._ccagt_info["image_id"].isin(test_ids), "image_name"].unique()
|
| 304 |
+
|
| 305 |
+
if self.config.name == "semantic_segmentation":
|
| 306 |
+
train_data = images_and_masks(train_bn_images)
|
| 307 |
+
valid_data = images_and_masks(valid_bn_images)
|
| 308 |
+
test_data = images_and_masks(test_bn_images)
|
| 309 |
+
elif self.config.name == "object_detection":
|
| 310 |
+
train_data = images_and_boxes(train_bn_images)
|
| 311 |
+
valid_data = images_and_boxes(valid_bn_images)
|
| 312 |
+
test_data = images_and_boxes(test_bn_images)
|
| 313 |
+
elif self.config.name == "instance_segmentation":
|
| 314 |
+
train_data = images_and_instances(train_bn_images)
|
| 315 |
+
valid_data = images_and_instances(valid_bn_images)
|
| 316 |
+
test_data = images_and_instances(test_bn_images)
|
| 317 |
+
else:
|
| 318 |
+
raise NotImplementedError
|
| 319 |
+
|
| 320 |
+
return [
|
| 321 |
+
datasets.SplitGenerator(
|
| 322 |
+
name=datasets.Split.TRAIN,
|
| 323 |
+
gen_kwargs={"data": train_data},
|
| 324 |
+
),
|
| 325 |
+
datasets.SplitGenerator(
|
| 326 |
+
name=datasets.Split.TEST,
|
| 327 |
+
gen_kwargs={"data": test_data},
|
| 328 |
+
),
|
| 329 |
+
datasets.SplitGenerator(
|
| 330 |
+
name=datasets.Split.VALIDATION,
|
| 331 |
+
gen_kwargs={"data": valid_data},
|
| 332 |
+
),
|
| 333 |
+
]
|
| 334 |
+
|
| 335 |
+
def _generate_examples(self, data):
|
| 336 |
+
if self.config.name == "semantic_segmentation":
|
| 337 |
+
for img_path, msk_path in data:
|
| 338 |
+
img_basename = get_basename(img_path)
|
| 339 |
+
image_id = self._bn_to_imageid[img_basename]
|
| 340 |
+
yield image_id, {
|
| 341 |
+
"image": img_path,
|
| 342 |
+
"annotation": msk_path,
|
| 343 |
+
}
|
| 344 |
+
elif self.config.name == "object_detection":
|
| 345 |
+
for img_path, labels in data:
|
| 346 |
+
img_basename = get_basename(img_path)
|
| 347 |
+
image_id = self._bn_to_imageid[img_basename]
|
| 348 |
+
yield image_id, {"image": img_path, "objects": labels}
|
| 349 |
+
elif self.config.name == "instance_segmentation":
|
| 350 |
+
for img_path, instances in data:
|
| 351 |
+
img_basename = get_basename(img_path)
|
| 352 |
+
image_id = self._bn_to_imageid[img_basename]
|
| 353 |
+
yield image_id, {"image": img_path, "objects": instances}
|
| 354 |
+
else:
|
| 355 |
+
raise NotImplementedError
|