journal,id,question,cover_image,answer,option_A,option_A_path,option_A_embedding_name,option_A_embedding_id,option_B,option_B_path,option_B_embedding_name,option_B_embedding_id,option_C,option_C_path,option_C_embedding_name,option_C_embedding_id,option_D,option_D_path,option_D_embedding_name,option_D_embedding_id,split
Current Biology,34_10,Which of the following options best describe the cover story?,"On the cover: White shark (Carcharodon carcharias) swimming in the clear waters around Guadalupe Island (Mexico). In this issue, Wagner et al. use genome-wide sequencing to show global white shark populations are divided into
three distinct genetic lineages: Atlantic/Mediterranean, North Pacific, and Indo-Pacific.
These lineages diverged 100,000–200,000 years ago and rarely interbreed. Image credit:
Getty/Cultura Exclusive/Rodrigo Friscione.",A,MAC_Bench/Cell/Cover/Current Biology/34_10.png,MAC_Bench/Cell/Cover/Current Biology/34_10.png,groundtruth,34_10.txt,MAC_Bench/Cell/Cover/Current Biology/32_1.png,MAC_Bench/Cell/Cover/Current Biology/32_1.png,ave_3,32_1.txt,MAC_Bench/Cell/Cover/Current Biology/19_13.png,MAC_Bench/Cell/Cover/Current Biology/19_13.png,vitg,19_13.txt,MAC_Bench/Cell/Cover/Current Biology/26_10.png,MAC_Bench/Cell/Cover/Current Biology/26_10.png,clip,26_10.txt,train
Nature Food,5_2,Which of the following options best describe the cover story?,"Cultivated meat techno-economic analyses
Cultivated meat could provide dietary protein with lower resource use than conventional beef production. Current techno-economic analyses exploring scaled-up production adopt different assumptions and processing approaches. Scale-up feasibility is likely to depend on the use of plant-based components to save costs on cell culture media, developing sustainable food-grade aseptic conditions and extensive scaling of related supply chains. Technological advancements need to address serum-free differentiation, new bioreactor designs, media recycling and valorization, and facility design that can support large-scale production.
See Shirwaiker et al.
Image: Jochen Tack / Alamy Stock Photo. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Food/2_1.png,MAC_Bench/Nature/Cover/Nature Food/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Food/3_3.png,MAC_Bench/Nature/Cover/Nature Food/3_3.png,vith,3_3.txt,MAC_Bench/Nature/Cover/Nature Food/3_10.png,MAC_Bench/Nature/Cover/Nature Food/3_10.png,ave_3,3_10.txt,MAC_Bench/Nature/Cover/Nature Food/5_2.png,MAC_Bench/Nature/Cover/Nature Food/5_2.png,groundtruth,5_2.txt,train
Trends in Genetics,40_2,Which of the following options best describe the cover story?,"The numerous alleles of the complementary sex determiner (csd) gene form
the basis of sex determination in the honeybee (Apis mellifera). In this issue, Jana Seiler
and Martin Beye review how different and identical csd alleles form a sex determination
signal and how this realizes sexual differentiation in downstream pathways. They also
discuss how mutation and selection have shaped the evolution and function of the
complementary sex determination system. Photograph by Christian Verhoeven.",C,MAC_Bench/Cell/Cover/Trends in Genetics/29_2.png,MAC_Bench/Cell/Cover/Trends in Genetics/29_2.png,clip,29_2.txt,MAC_Bench/Cell/Cover/Trends in Genetics/35_9.png,MAC_Bench/Cell/Cover/Trends in Genetics/35_9.png,ave_2,35_9.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_2.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_2.png,groundtruth,40_2.txt,MAC_Bench/Cell/Cover/Trends in Genetics/39_6.png,MAC_Bench/Cell/Cover/Trends in Genetics/39_6.png,ave_3,39_6.txt,val
Trendsin Neurosciences,47_9,Which of the following options best describe the cover story?,"Research in brain aging has historically focused on advanced age, when
the effects of time on cognitive health and physical functioning are most manifest.
However, an increasing number of studies are finding that changes during middle
age are prognostic of future cognitive health. In this issue of Trends in Neurosciences,
Dohm-Hansen and colleagues review emerging evidence indicating that middle age is
a period defined by unique processes both within and outside the brain that influence
cognitive aging trajectories. Many of these processes, ranging from genetic expression
to memory for everyday events, display non-linear relationships with chronological
age.
This opens for the possibility of identifying aging processes that are especially
relevant
during middle age and could have bearing on health trajectories in later life. Photo
credits: Ivcandy/Getty Images and Macauley Smith Breault/SciDraw.",B,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_8.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_8.png,vith,37_8.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_9.png,groundtruth,47_9.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/39_6.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/39_6.png,vitg,39_6.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_7.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_7.png,clip,47_7.txt,train
Nature Protocols,19_12,Which of the following options best describe the cover story?,"Label-free X-ray microscopy of nanomedicines and organelles in intact single cells at nanometer resolution using synchrotron radiation
A composite image of a single cell visualized in 3D and a synchrotron radiation facility. The method uses X-rays generated via synchrotron radiation and enables the subcellular localization of nanomedicines in single cells, at nanometer resolution, as a robust approach to characterize interactions between nanomaterials and cells. See Cao et al.
Image: Mingjing Cao, Yaling Wang and Chunying Chen, National Center for Nanoscience and Technology of China. Cover design: S. Whitham.",D,MAC_Bench/Nature/Cover/Nature Protocols/14_1.png,MAC_Bench/Nature/Cover/Nature Protocols/14_1.png,vitg,14_1.txt,MAC_Bench/Nature/Cover/Nature Protocols/16_11.png,MAC_Bench/Nature/Cover/Nature Protocols/16_11.png,clip,16_11.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_11.png,MAC_Bench/Nature/Cover/Nature Protocols/15_11.png,vith,15_11.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_12.png,MAC_Bench/Nature/Cover/Nature Protocols/19_12.png,groundtruth,19_12.txt,train
ACS Bio & Med Chem Au,2024_3,Which of the following options best describe the cover story?,Hwang et al. develop a new sustainable bioproduction platform to generate disulfide-constrained peptide (DCP) and its functionalized analogues. DCPs are targeted to the periplasm in E.,B,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_3.png,ave_2,2022_3.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2023_1.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_5.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_5.png,clip,2022_5.txt,train
Biophysical Reports,4_2,Which of the following options best describe the cover story?,"On the cover: The cover shows an illustration of a new, multipurpose, graphical user
interface-based open-source toolbox offering unbiased analysis of single-molecule
spectroscopic data. DOI: https://doi.org/10.1016/j.bpr.2024.100173.",D,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,clip,4_3.txt,MAC_Bench/Cell/Cover/Biophysical Reports/2_3.png,MAC_Bench/Cell/Cover/Biophysical Reports/2_3.png,ave_1,2_3.txt,MAC_Bench/Cell/Cover/Biophysical Reports/3_4.png,MAC_Bench/Cell/Cover/Biophysical Reports/3_4.png,ave_2,3_4.txt,MAC_Bench/Cell/Cover/Biophysical Reports/4_2.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_2.png,groundtruth,4_2.txt,test
Cell Reports Physical Science,5_4,Which of the following options best describe the cover story?,"On the cover: The cover of this month’s issue of Cell Reports Physical Science summarizes the research of Li et al. on the preparation of multiscale hydrogels. The background represents a hydrogel’s
macroporous structure, which provides space for cells. The hydrogel (upper left) affects
mesenchymal stem-cell fate with local stiffness-enhancing structures (lower left)
and promotes bone regeneration (bottom right). This research has promising applications,
such as the possibility to be used as a 3D printing ink (upper right). The cover was
produced by Zhibao Xiao.",D,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,vitg,5_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_10.png,vith,3_10.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_4.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_4.png,clip,4_4.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_4.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_4.png,groundtruth,5_4.txt,train
Nature Reviews Materials,9_3,Which of the following options best describe the cover story?,"Universal access to fresh water and modern energy are key to a sustainable and just future. Sorbent materials that capture and release water molecules are at the heart of technologies that turn the Earth’s abundant atmospheric moisture into drinkable water and energy, making these essential resources more accessible to all. See the Editorial
Cover image: Jiaxing Xu, Tingxian Li and Hangzhou Sphere Studio. Cover design: David Johnston.",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,vith,9_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_6.png,vitg,7_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_8.png,clip,5_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_3.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_3.png,groundtruth,9_3.txt,val
Nature Water,2_12,Which of the following options best describe the cover story?,"Drinking water in small and remote communities
While most people in high-income countries have access to safely managed drinking water, there are still gaps in service provision that prevent countries from meeting the SDG 6.1 target of “achieving universal and equitable access to safe and affordable drinking water for all by 2030”. In Australia, for example, drinking water quality breaches have been documented in small, rural and remote (SRR) communities. Ana Manero and colleagues have now estimated the Australian residents’ willingness to pay for improved drinking water services in these SRR communities.
The cover shows the painting The Unity of Water by Walmajarri, Gooniyandi, Bunuba and Nyikina man — Hozaus Claire. In the artist’s own words: “Every water is connected in many ways. Water has its own cycle to resource the natural environment. Every water has a story, every story has a meaning. All surface water has different tribes that tells a story about the water and connection to the First Law of the Land. And the access to the water provides leadership to the tribes that lives near the water that keeps the story strong. The ground water has a significant and secret story that keeps the spirit of the water and the land alive. That is why every river is connected. The connection is under the ground on the land and in the air. How the animals use the water is how people should treat the water and listen to our Elders story songs and dance. The spirit of water is only listened to and seen. In the songs stories and dance of the First Nation of the Land. In this painting, I show connections of ground water and surface water. It also shows that water holes, creeks, springs, rivers and ocean are connected.”
See Manero et al.
IMAGE: The cover shows the painting The Unity of Water by Walmajarri, Gooniyandi, Bunuba and Nyikina man — Hozaus Claire. COVER DESIGN: Valentina Monaco.",A,MAC_Bench/Nature/Cover/Nature Water/2_12.png,MAC_Bench/Nature/Cover/Nature Water/2_12.png,groundtruth,2_12.txt,MAC_Bench/Nature/Cover/Nature Water/2_2.png,MAC_Bench/Nature/Cover/Nature Water/2_2.png,ave_2,2_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_4.png,MAC_Bench/Nature/Cover/Nature Water/2_4.png,clip,2_4.txt,MAC_Bench/Nature/Cover/Nature Water/1_11.png,MAC_Bench/Nature/Cover/Nature Water/1_11.png,ave_3,1_11.txt,train
Neuron,113_4,Which of the following options best describe the cover story?,"On the cover: In this special issue of Neuron, we present a collection of reviews and perspectives on the neurobiology of aging.
The causes of brain aging are multidimensional and complex. Highlighting this, the
cover image is provided by Schwartz and colleagues, who discuss the impact of the immune system on brain aging and propose the provocative
idea of anti-aging immune therapy.",B,MAC_Bench/Cell/Cover/Neuron/73_3.png,MAC_Bench/Cell/Cover/Neuron/73_3.png,ave_2,73_3.txt,MAC_Bench/Cell/Cover/Neuron/113_4.png,MAC_Bench/Cell/Cover/Neuron/113_4.png,groundtruth,113_4.txt,MAC_Bench/Cell/Cover/Neuron/113_1.png,MAC_Bench/Cell/Cover/Neuron/113_1.png,clip,113_1.txt,MAC_Bench/Cell/Cover/Neuron/75_4.png,MAC_Bench/Cell/Cover/Neuron/75_4.png,ave_3,75_4.txt,val
Journal of Chemical Information and Modeling,2025_1,Which of the following options best describe the cover story?,"This figure shows materials being ""scanned"" by AI, as our method applies an AI-based filter to assess prediction reliability of AI-based regression models. The depicted structures are from the COD database (CC0 license) and were processed using the Avogadro software.",C,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2016_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2016_11.png,ave_1,2016_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2010_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2010_6.png,clip,2010_6.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_6.png,ave_2,2015_6.txt,train
Nature Reviews Physics,6_6,Which of the following options best describe the cover story?,"The cover of this issue is based on a network of ferroelectric domain walls in ErMnO3. See Everschor-Sitte et al.
Image: Dennis Meier, Jakob Schaab, amb design & illustrations. Cover design: Susanne Harris. [Note: The image credit originally published was incorrect; it has now been updated.]",D,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_4.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_4.png,vitg,5_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_6.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_6.png,vith,3_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_6.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_6.png,groundtruth,6_6.txt,train
Journal of Chemical Theory and Computation,2024_14,Which of the following options best describe the cover story?,"This work presents a novel automatic machine learning-based manifold learning approach to discover essential transition components with kinetic properties. The circuit in the cover story represents neurons transmitting kinetic information from high-dimensional space into the protein structure of interest. The conformational space of the peptide (shown as sticks) is explored comprehensively in the protein pocket with shape complementarity considered. The lower curves with starring points indicate the long-lasting conformations, which can be used to guide subsequent drug design and lead optimization.",C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_17.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_17.png,vith,2023_17.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2019_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2019_2.png,vitg,2019_2.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_14.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_10.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_10.png,clip,2022_10.txt,train
Nature Reviews Clinical Oncology,21_9,Which of the following options best describe the cover story?,"Dendritic cells as orchestrators of immune responses, inspired by the Review on p257.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_2.png,clip,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_9.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_9.png,groundtruth,21_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_11.png,vith,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_4.png,vitg,20_4.txt,test
CHEMICAL REVIEWS,2025_1,Which of the following options best describe the cover story?,"Illustration of an electrochemical random access memory (ECRAM) that functions by moving mobile defects, such as protons, lithium ions, or oxygen vacancies, between the top (reservoir) and bottom (channel) electrodes made of various functional materials and connected by a solid electrolyte (middle, light blue). The mobile defects tune the electronic conductance through reversible redox reactions. Although ECRAM shares many fundamental aspects with rechargeable batteries, computing applications require many millions of devices, scaled down to sub-micrometer dimensions, while achieving reliable electronic-state tuning at scaled-up rates and endurances and with minimal energy dissipation.",C,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_4.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_4.png,clip,2016_4.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2022_21.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2022_21.png,vith,2022_21.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_1.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2023_17.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2023_17.png,ave_1,2023_17.txt,test
Nature Reviews Psychology,3_12,Which of the following options best describe the cover story?,"This month we launch a new collection of pieces that highlight ways to improve doctoral education and support graduate student trainees to their fullest potential.
Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_2.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_2.png,ave_2,2_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/4_1.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/4_1.png,clip,4_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_3.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_3.png,vitg,3_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_12.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_12.png,groundtruth,3_12.txt,train
Nature Mental Health,3_1,Which of the following options best describe the cover story?,"Machine learning in mental health research
The capabilities of machine learning, and artificial intelligence more broadly, have captured our collective imagination. A discipline that once seemed more like science fiction, machine learning is now being harnessed and applied to many fields, including psychiatry and mental health research. Machine learning holds the ability to combine massive datasets — brain scan images, electronic health records and real-time affective measurements — to identify relationships and patterns among variables that may be used to stratify risk, diagnose disorders or predict treatment response. The January cover is intended to evoke the notion that applying machine learning techniques in mental health research is both an art and a science. Just as machine learning models must be refined by human-defined parameters, researchers are also learning how best to apply these techniques in a symbiotic relationship between humans and technology.
Read more in our Editorial, and see Lucasius et al.on using machine learning in psychiatry.
Image: Marina Spence and Jackie Niam / iStock / Getty Images Plus. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/Nature Mental Health/1_4.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_4.png,ave_2,1_4.txt,MAC_Bench/Nature/Cover/Nature Mental Health/3_1.png,MAC_Bench/Nature/Cover/Nature Mental Health/3_1.png,groundtruth,3_1.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,ave_3,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,clip,2_6.txt,val
Structure,33_2,Which of the following options best describe the cover story?,"On the cover: Alternative complex III from Chloroflexus aurantiacus (CaACIII) is a multi-subunit quinol acceptor oxidoreductase that couples quinol oxidation
with transmembrane proton translocation in respiratory and photosynthetic electron
transport chains. This image shows CaACIII structures determined by X-ray crystallography
and cryoelectron microscopy. The CaACIII crystal structure presented in this issue
by Wu et al. highlights the conformational stability of its core functional modules and reveals
local flexibility in regions with low sequence conservation.",B,MAC_Bench/Cell/Cover/Structure/29_6.png,MAC_Bench/Cell/Cover/Structure/29_6.png,clip,29_6.txt,MAC_Bench/Cell/Cover/Structure/33_2.png,MAC_Bench/Cell/Cover/Structure/33_2.png,groundtruth,33_2.txt,MAC_Bench/Cell/Cover/Structure/22_7.png,MAC_Bench/Cell/Cover/Structure/22_7.png,vith,22_7.txt,MAC_Bench/Cell/Cover/Structure/32_5.png,MAC_Bench/Cell/Cover/Structure/32_5.png,vitg,32_5.txt,test
ACS Chemical Neuroscience,2024_19,Which of the following options best describe the cover story?,"This image shows a large subpopulation of 5-HT neurons (TPH2 immunolabeling in red) expressing the vesicular glutamate transporter 3 (VGLUT3 immunolabeling in green), thus having the capacity to co-release both 5-HT and glutamate. Gullino et al. show that these neurons are involved in",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_19.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_19.png,groundtruth,2024_19.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_22.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_22.png,clip,2021_22.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,ave_2,2022_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_3.png,vith,2017_3.txt,train
Nature Electronics,7_4,Which of the following options best describe the cover story?,"An optical neural interface in miniature
A miniaturized implantable optical device, which is thin enough to lie within the subdural space of a primate brain, can be created using an integrated circuit that provides both fluorescence imaging and optogenetic stimulation. The optical microscopy image on the cover shows a section of the integrated circuit, which is fabricated using complementary metal–oxide–semiconductor (CMOS) technology, and highlights the photodiode pixels used for imaging in the neural interface.
See Pollmann et al.
Image: Eric Pollmann, Columbia University. Cover design: Lauren Heslop.",A,MAC_Bench/Nature/Cover/Nature Electronics/7_4.png,MAC_Bench/Nature/Cover/Nature Electronics/7_4.png,groundtruth,7_4.txt,MAC_Bench/Nature/Cover/Nature Electronics/1_1.png,MAC_Bench/Nature/Cover/Nature Electronics/1_1.png,vitg,1_1.txt,MAC_Bench/Nature/Cover/Nature Electronics/6_4.png,MAC_Bench/Nature/Cover/Nature Electronics/6_4.png,clip,6_4.txt,MAC_Bench/Nature/Cover/Nature Electronics/5_7.png,MAC_Bench/Nature/Cover/Nature Electronics/5_7.png,vith,5_7.txt,train
Developmental Cell,59_3,Which of the following options best describe the cover story?,"On the cover: This image depicts mRNA translation within the appressorium of the rice
blast fungus Magnaporthe oryzae. Ribosomes (purple) move along the mRNA, decoding genetic information. The eukaryotic
elongation factor (eEF1, yellow) escorts aminoacyl-tRNA (blue) to the ribosome, facilitating
protein synthesis. A conserved tRNA modification (red dot) enhances eEF1-tRNA interaction,
promoting the translation of genes essential for appressorium function and fungal
infection. In the upper right, an asexual spore develops into a dome-shaped appressorium
(gray) following this mRNA translation. To learn more about how this modification
controls fungal infection, see He et al. Image credit: Rongrong He, Yinan Li, and Zhipeng Zhou.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_3.png,MAC_Bench/Cell/Cover/Developmental Cell/59_3.png,groundtruth,59_3.txt,MAC_Bench/Cell/Cover/Developmental Cell/17_5.png,MAC_Bench/Cell/Cover/Developmental Cell/17_5.png,clip,17_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/18_5.png,MAC_Bench/Cell/Cover/Developmental Cell/18_5.png,vith,18_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/53_6.png,MAC_Bench/Cell/Cover/Developmental Cell/53_6.png,vitg,53_6.txt,test
Environment & Health,2024_2,Which of the following options best describe the cover story?,"Prenatal exposure to F-53B exerts detrimental effects on synaptic development in fetal mice. F-53B could bind with the protein of PKA and CREB1 in hippocampal neurons of mice which prevents PKA translocation from cytoplasm to nucleus, and further inhibits the phosphorylation of nuclear CREB.",B,MAC_Bench/ACS/Cover/Environment & Health/2024_11.png,MAC_Bench/ACS/Cover/Environment & Health/2024_11.png,ave_2,2024_11.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_2.png,MAC_Bench/ACS/Cover/Environment & Health/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,ave_3,2023_1.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,clip,2024_7.txt,val
Nature Chemistry,16_12,Which of the following options best describe the cover story?,"Identifying an elusive intermediate
Trans–cis photoisomerization plays an essential role in various biological settings such as vision, ion pumping, and light sensing. The prototypical trans–cis photoisomerization of stilbenes (an artistic impression of which is depicted on the cover) is thought to occur via an intermediate with a perpendicular conformation; however, its unambiguous identification has thus far proved difficult. Using ultrafast Raman spectroscopy and ab initio molecular dynamics simulations, Tahei Tahara and colleagues now characterize the common, perpendicular intermediate of stilbene photoisomerization, revealing its ultrafast birth and decay upon photoexcitation of the trans and cis forms.
See Kuramochi et al.
Image: Takaya Fukui, Art Action Inc.. Cover design: Tulsi Voralia",C,MAC_Bench/Nature/Cover/Nature Chemistry/13_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/13_6.png,vitg,13_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/14_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/14_6.png,vith,14_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_12.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_12.png,groundtruth,16_12.txt,MAC_Bench/Nature/Cover/Nature Chemistry/11_5.png,MAC_Bench/Nature/Cover/Nature Chemistry/11_5.png,clip,11_5.txt,train
Nature Reviews Chemistry,8_2,Which of the following options best describe the cover story?,"The depolymerization of lignin is represented by a wooden block at the centre of the image surrounded by the products of breakdown and catalysts that have been applied in this important biomass valorization reaction. Lignin is a heterogeneous aromatic macromolecule found in the cell walls of plants. Its conversion to useful monomers is considered key to a transition away from fossil fuel feedstocks. Although there has been much research into C-O cleavage, commercial use of a far greater proportion of available lignin requires cleavage of C-C bonds, which has proven particularly challenging both to develop and to quantify, see Palumbo et al.
Image: Rita Clare; Cover design: Carl Conway",A,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_2.png,groundtruth,8_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_8.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_8.png,vith,7_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_6.png,clip,1_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_11.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_11.png,vitg,7_11.txt,train
ACS ES&T Water,2024_3,Which of the following options best describe the cover story?,The superior sensitivity and specificity of qPCR allow for the quantification of algal genera and the discovery of algae response to reservoir characteristics that traditional microscopy methods could not easily detect.,A,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_11.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_11.png,vith,2024_11.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_5.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_5.png,clip,2022_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,vitg,2025_1.txt,train
Nature Computational Science,4_2,Which of the following options best describe the cover story?,"Impact of generative AI on e-waste
The rising popularity and usage of generative artificial intelligence (AI) amongst the general public and for research purposes has contributed to an increase in electronic waste (e-waste). In this issue, Peng Wang and colleagues propose a computational framework to quantify the amount of e-waste that is produced by generative AI, particularly large language models, highlighting the potential for rapid e-waste growth under different scenarios and emphasizing the need for circular economies and proactive e-waste management strategies.
See Peng Wang et al. and Loïc Lannelongue
Image: Guillaume Payen / LightRocket / Getty Images. Cover design: Alex Wing.",A,MAC_Bench/Nature/Cover/Nature Computational Science/4_2.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_2.png,groundtruth,4_2.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,vitg,4_8.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_12.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_12.png,clip,3_12.txt,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,vith,5_1.txt,test
Trends in Endocrinology & Metabolism,35_6,Which of the following options best describe the cover story?,"This month we are celebrating Cell’s 50th anniversary by focusing on
the exciting metabolic research that Cell Press publishes across its titles. This
month’s
covers of Cell Metabolism, Cell and Trends in Endocrinology & Metabolism, when put side-by-side, form a single image, reflective of the variety of topics
on metabolic
research that you will find across the three journals and the connections between
them.
Our cover reflects some of the contents of this issue, spanning from chronotherapy
in cardiovascular care (Festus et al, pp 607–623) to beta cell senescence in type 1
and type 2 diabetes (Morelli et al, pp 576–585), to fetal outcomes in maternal obesity
(Zhang et al, 638–647) and more. Artwork credit: Sonhita Chakraborty",A,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_6.png,groundtruth,35_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,vith,27_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_3.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_3.png,clip,35_3.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/28_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/28_6.png,vitg,28_6.txt,train
ACS ES&T Air,2024_9,Which of the following options best describe the cover story?,An inverse modeling approach is developed to refine emission inventories and enhance air quality prediction by a combined use of PM2.5 data measured by a high-grade accurate instrument in the US embassy with low-cost PurpleAir sensor data from citizens for such developing countries as in Ethiopia where a national air quality observation network does not exist. Image generated by DALL·E 3 (OpenAI) and modified using Clip Studio.,B,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,vitg,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,ave_2,2024_3.txt,train
ACS Synthetic Biology,2024_6,Which of the following options best describe the cover story?,This cover describes a method of metabolic engineering for the production of ectoine based on the heterologous expression of ectoine synthesis-related genes in Corynebacterium glutamicum to increase ectoine production.,B,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,ave_3,2015_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_11.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_11.png,vitg,2015_11.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_5.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_5.png,clip,2024_5.txt,test
Science Robotics,10_99,Which of the following options best describe the cover story?,"ONLINE COVER Biohybrid Robots—Controlling Robotic Hand Movement with Muscle Tissue. Biohybrid robots provide the advantage of combining muscle tissue derived from cells as well as synthetic components. These muscle tissues can be controlled to generate contractile forces necessary to provide linear movement of joints. Ren et al. have developed a multifingered robotic hand that was powered by bundles of muscle tissue. The muscles were connected to tendons and ultimately to the individual fingers, which could be controlled independently to generate flexion when exposed to electrical stimulation. This month’s cover is an image of the biohybrid robotic hand showing the fingers in flexion. Credit: : Shoji Takeuchi research group/University of Tokyo",C,MAC_Bench/Science/Cover/Science Robotics/10_98.png,MAC_Bench/Science/Cover/Science Robotics/10_98.png,vith,10_98.txt,MAC_Bench/Science/Cover/Science Robotics/5_46.png,MAC_Bench/Science/Cover/Science Robotics/5_46.png,clip,5_46.txt,MAC_Bench/Science/Cover/Science Robotics/10_99.png,MAC_Bench/Science/Cover/Science Robotics/10_99.png,groundtruth,10_99.txt,MAC_Bench/Science/Cover/Science Robotics/7_67.png,MAC_Bench/Science/Cover/Science Robotics/7_67.png,vitg,7_67.txt,train
Nature Reviews Physics,6_11,Which of the following options best describe the cover story?,"The cover of this issue illustrates the search for an island of nuclear stability, a metaphor that has by now shifted towards glimpsing the mountains of enhanced stability on the horizon, their tops still concealed by clouds. See >[Smits] et al.
Cover design: Susanne Harris.",B,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_1.png,vith,4_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_11.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_11.png,groundtruth,6_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_5.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_5.png,vitg,4_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_9.png,clip,5_9.txt,test
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_2,Which of the following options best describe the cover story?,"‘Gates and channels’, inspired by the Reviews on p904 and p886
Cover design: Vicky Summersby",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,clip,24_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_2.png,ave_2,26_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.png,vitg,26_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_2.png,groundtruth,25_2.txt,test
Trends in Cognitive Sciences,28_8,Which of the following options best describe the cover story?,"Developing tests that could be used to detect consciousness in immature
and non-responsive humans, non-human animals, brain organoids, and AI systems is
one of the central challenges facing science. Addressing this challenge would not
only
have important implications for the science of consciousness but would also have
profound ethical and social implications. In this issue of Trends in Cognitive Sciences,
Tim Bayne and colleagues review some of the leading tests for consciousness that
have been developed to date, clarify the logical structure of various possible tests
for
consciousness, and critically evaluate three strategies for validating a consciousness
test. The cover image depicts two of the many kinds of organisms to which a test for
consciousness might be applied. Cover art by James Croxford.",B,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_6.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_6.png,ave_1,20_6.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_8.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_8.png,groundtruth,28_8.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_1.png,vitg,20_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/26_5.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/26_5.png,clip,26_5.txt,test
Cell Systems,15_8,Which of the following options best describe the cover story?,"On the cover: VelvetSDE simulations of early neural progenitors differentiating into
motor neurons, V3 interneurons, and floor plate cells, coloured by fate and visualised
in PCA space of VelvetSDE latent space representation. Maizels et al. present methods for dynamical modeling from single-cell transcriptomics: an experimental
protocol for metabolic labeling that provides increased data quality with single-cell
temporal resolution and a generative modeling framework for velocity inference that
outperforms other tools and provides trajectory simulations that capture dynamical
aspects of cell fate decisions. Image credit: the authors.",A,MAC_Bench/Cell/Cover/Cell Systems/15_8.png,MAC_Bench/Cell/Cover/Cell Systems/15_8.png,groundtruth,15_8.txt,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,ave_1,4_4.txt,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,vitg,7_2.txt,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,clip,1_5.txt,train
Nature Astronomy,9_1,Which of the following options best describe the cover story?,"Galactic fireworks from cosmic dawn
13.4-billion-year-old photons reveal the extreme conditions in one of the most distant known galaxies. This illustration highlights the JWST/MIRI spectrum of galaxy GHZ2/GLASS-z12, in which atomic transitions from hydrogen and oxygen are present.
See Zavala et al.
Image: César Augusto Huato Méndez & Jorge A. Zavala (Background image: JWST, NASA/ESA/CSA. Composition by Diego Paris). Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Astronomy/9_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/4_11.png,MAC_Bench/Nature/Cover/Nature Astronomy/4_11.png,clip,4_11.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,vitg,2_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,ave_3,1_1.txt,train
ACS ES&T Engineering,2024_12,Which of the following options best describe the cover story?,This special issue showcases the latest research in the application of computational modeling in environmental research. The front cover shows that the density functional theory (DFT) calculation of aperiodic small molecule systems is a cost-effective and promising approach for investigating the reaction mechanisms of advanced oxidation processes at the subatomic level,A,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_12.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_3.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_3.png,clip,2023_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_11.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_11.png,vith,2022_11.txt,train
CELL RESEARCH,34_8,Which of the following options best describe the cover story?,"The image illustrates a Chinese historical story, depicting Taigong Jiang fishing with his hook, reminiscent of the innovative proximity labeling tool, PhastID. PhastID identifies ATP6AP1, an unconventional GEF of Rheb. The C-tail at the end of ATP6AP1 can be used as a switch for Rheb to regulate the activation of mTORC1 signaling. Just as the two different states of the fish in the image, activating Rheb or not has distinct impacts on cellular functions. See page 355–369 by Ran Feng et al. for details.",A,MAC_Bench/Nature/Cover/CELL RESEARCH/34_8.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_8.png,groundtruth,34_8.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_1.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_1.png,ave_3,32_1.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png,ave_2,34_7.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_3.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_3.png,clip,34_3.txt,train
Cell Systems,16_1,Which of the following options best describe the cover story?,"On the cover: Heatmap of temporal activity of ERK, measured using the modified ERK
kinase translocation reporter (KTR) and read out as cytoplasmic:nuclear ratio in thousands
of single A375 cells, before and after treatment with 10 nM Trametinib indicated by
the black line. In this issue of Cell Systems, Hoffman et al. find that ERK and p38 KTRs can be partly phosphorylated by CDK2, a phenomenon unmasked
under MAPK pathway inhibition. The authors show that the modified FRET-based sensor,
EKAREN5, does not show this crosstalk and that, by co-expressing the ERK or p38 KTR
with the CDK2 sensor, contributions of CDK2 activity on the KTR signals can be removed.
Image credit: the authors.",A,MAC_Bench/Cell/Cover/Cell Systems/16_1.png,MAC_Bench/Cell/Cover/Cell Systems/16_1.png,groundtruth,16_1.txt,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,vitg,7_2.txt,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,vith,11_2.txt,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,clip,1_2.txt,train
ACS Chemical Neuroscience,2024_11,Which of the following options best describe the cover story?,"Ligands with multipotent profile binding with different targets, such as acetylcholine esterase, monoamine oxidase, and amyloid β: Multipotent ligands are expected to display neuroprotection and neurorescue potential along with reactive species inhibition activity for the effective treatment of Alzheimer’s disease.",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_11.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2018_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2018_6.png,clip,2018_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_13.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_13.png,ave_0,2021_13.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_10.png,vitg,2022_10.txt,train
Trendsin Neurosciences,47_3,Which of the following options best describe the cover story?,"Left-right asymmetry in brain function and neuronal circuits is a conserved
feature among bilaterians, playing crucial roles in perception, cognition, and behavior.
In this issue of Trends in Neurosciences, François Lapraz, Cloé Fixary-Schuster, and
Stéphane Noselli explore recent findings in nematode, zebrafish, and Drosophila
models, highlighting the relationship between body and brain asymmetries and the
evolutionary conservation of laterality mechanisms and function. The cover image
showcases asymmetrical Drosophila H-neurons overlayed onto a reference brain
(fruitfly.tefor.net). It features a composite of single neuron clones, with one left
(magenta) and one right (cyan) H-neuron sending projections specifically into the
right
asymmetrical body, with no projection to the left one. Cover image acquired by Céline
Boutres and designed by François Lapraz, Cloé Fixary-Schuster, and Stéphane Noselli.",A,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,groundtruth,47_3.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/41_3.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/41_3.png,clip,41_3.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,vitg,43_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_6.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_6.png,vith,43_6.txt,test
ACS Materials Au,2024_2,Which of the following options best describe the cover story?,"The modern semiconductor industry highly demands efficient photoresists suitable to EUV nanolithography. Yoon and colleagues synthesized a novel macrocyclic multinuclear tin complex and conducted an in-depth investigation into its photochemical behavior. The photoresist exhibited small line-edge roughness in EUV lithography, underscoring its potential as an efficient EUV photoresist. AI was used in the creation of the cover image.",A,MAC_Bench/ACS/Cover/ACS Materials Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_4.png,clip,2023_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,ave_2,2023_2.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_6.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_6.png,vitg,2022_6.txt,train
Med,5_12,Which of the following options best describe the cover story?,"On the cover: Many human diseases display variations in their phenotypic manifestation,
which can be attributed to a complex interplay between underlying genetic factors.
In this issue, Levine et al. utilize data from the Human Phenotype Project to map the genetic correlates associated
with traits such as blood sugar levels and sleep quality, providing higher-resolution
links to disease than simple clinical diagnoses. This work suggests that phenotypic
associations may be useful in detecting disease-linked genetic signals before the
threshold for a clinical diagnosis is crossed and offers publicly accessible tools
to further map the exact genetic mechanisms underlying various aspects of human health
and disease. Cover art from Boris SV/Moment via Getty Images.",B,MAC_Bench/Cell/Cover/Med/5_3.png,MAC_Bench/Cell/Cover/Med/5_3.png,vitg,5_3.txt,MAC_Bench/Cell/Cover/Med/5_12.png,MAC_Bench/Cell/Cover/Med/5_12.png,groundtruth,5_12.txt,MAC_Bench/Cell/Cover/Med/5_7.png,MAC_Bench/Cell/Cover/Med/5_7.png,vith,5_7.txt,MAC_Bench/Cell/Cover/Med/4_2.png,MAC_Bench/Cell/Cover/Med/4_2.png,clip,4_2.txt,train
NATURE GENETICS,56_9,Which of the following options best describe the cover story?,"Coffea arabica diversification history
Genome assemblies of allotetraploid Coffea arabica and representatives of its diploid progenitors provide insights into diversification history.
See Salojärvi et al.
Image: Amanda van der Sijs/500px/Getty. Cover design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/NATURE GENETICS/56_9.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_9.png,groundtruth,56_9.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_9.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_9.png,vitg,49_9.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_11.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_11.png,clip,56_11.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/53_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/53_1.png,vith,53_1.txt,test
ACS Applied Polymer Materials,2024_18,Which of the following options best describe the cover story?,"niversal controlled-release system based on cubosome-carrying bacterial cellulose capsules with a pH-smart trigger mechanism for the oral administration of therapeutic bioactives is rationally designed. Site-specific, dual cargo-controlled release is achieved through a solubility-dependent phenomenon. Such an engineered pH-responsive microcapsule has potential for colon-targeted multidrug delivery.",B,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_1.png,ave_2,2022_1.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_18.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_18.png,groundtruth,2024_18.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,ave_3,2020_12.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,clip,2025_2.txt,train
Nature Cardiovascular Research,3_2,Which of the following options best describe the cover story?,"Sleep and atherosclerosis
Kiss et al. review preclinical and clinical evidence that illustrates how sleep influences the nervous, metabolic and immune systems, with inadequate sleep affecting the risk of atherosclerotic cardiovascular disease.
See Kiss et al.
Image: Siesta, Henri Manguin – Heritage Image Partnership / Alamy Stock Photo. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,vitg,2_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_2.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_2.png,groundtruth,3_2.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_6.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_6.png,ave_3,3_6.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_3.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_3.png,clip,3_3.txt,train
Nature Nanotechnology,19_8,Which of the following options best describe the cover story?,"Flexible tandem light-emitting diodes
The cover image depicts a flexible 10 × 10 matrix of narrow-band and high-efficiency green tandem light-emitting diodes, combining nanocrystal perovskite light-emitting diode and organic light-emitting diode units.
See Lee et al.
Image: Tae-Woo Lee / Seoul National University. Cover design: Valentina Monaco",B,MAC_Bench/Nature/Cover/Nature Nanotechnology/15_1.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/15_1.png,vith,15_1.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_8.png,groundtruth,19_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_9.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_9.png,vitg,18_9.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,train
Structure,32_3,Which of the following options best describe the cover story?,"On the cover: Synaptotagmin-1 C2A and C2B domains bind to model lipid bilayers mimicking
the synaptic plasma membrane (C2B) and the synaptic vesicle membrane (C2A). A native
mass spectrum of Synaptotagmin-1 binding to DOPS at different stoichiometries is shown
below the plasma membrane plane. Bender et al. combined native mass spectrometry and protein-lipid binding assays with molecular
dynamics simulations to investigate the lipid preferences of the two Synaptotagmin-1
C2 domains. Image credit: Julian Bender.",C,MAC_Bench/Cell/Cover/Structure/32_11.png,MAC_Bench/Cell/Cover/Structure/32_11.png,vitg,32_11.txt,MAC_Bench/Cell/Cover/Structure/28_11.png,MAC_Bench/Cell/Cover/Structure/28_11.png,clip,28_11.txt,MAC_Bench/Cell/Cover/Structure/32_3.png,MAC_Bench/Cell/Cover/Structure/32_3.png,groundtruth,32_3.txt,MAC_Bench/Cell/Cover/Structure/24_12.png,MAC_Bench/Cell/Cover/Structure/24_12.png,vith,24_12.txt,train
NATURE MATERIALS,23_12,Which of the following options best describe the cover story?,"Magnetoelectric metamaterials for neurostimulation
Self-rectifying magnetoelectric metamaterials with nonlinear responses generate electrical pulse sequences that enable precisely timed remote neural stimulation and restoration of sensory motor responses in vivo.
See Chen et al.
Image: Maayan Harel. Cover design: Alex Whitworth",C,MAC_Bench/Nature/Cover/NATURE MATERIALS/9_7.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/9_7.png,clip,9_7.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/14_7.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_12.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_12.png,groundtruth,23_12.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_4.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_4.png,vitg,19_4.txt,train
Trends in Immunology,45_1,Which of the following options best describe the cover story?,"On pages 971–986, Jorfi, Tanzi, and colleagues discuss the role peripheral
immune cells play in contributing to Alzheimer’s disease (AD) pathology, and recent
approaches for studying neuroimmune interactions. The illustration depicts a human
brain where half includes forget-me-not flowers (symbols of AD) that are floating
away.
Therapeutically targeting peripheral immune cells might contribute to ameliorating
AD
and preserving memory. The artist wanted to suggest that the person facing the bright
light looks at a hopeful.",C,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,ave_3,36_4.txt,MAC_Bench/Cell/Cover/Trends in Immunology/38_2.png,MAC_Bench/Cell/Cover/Trends in Immunology/38_2.png,vitg,38_2.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_1.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_1.png,groundtruth,45_1.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,clip,36_3.txt,train
Nature Chemistry,16_3,Which of the following options best describe the cover story?,"Solid-state superionic conductivity
All-solid-state batteries offer a safer alternative to conventional lithium-ion batteries, but the solid electrolytes necessary to transport lithium ions between electrodes display poor room-temperature conductivities. Now, Jue Liu, Yifei Mo, and Hailong Chen show how a family of electrolyte solids undergo a temperature-triggered transition from low to high conductivities due to collective anion motion. Using the uncovered structure–property relationships, they develop new electrolytes with lower transition temperatures to achieve superionic conductivities at room temperature. The cover shows an artistic representation of lithium-ion movement through the solid-state electrolyte.
See Chen et al.
Image: Phoenix Pleasant / ORNL, U.S. Dept. of Energy. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Chemistry/13_4.png,MAC_Bench/Nature/Cover/Nature Chemistry/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/Nature Chemistry/6_1.png,MAC_Bench/Nature/Cover/Nature Chemistry/6_1.png,vitg,6_1.txt,MAC_Bench/Nature/Cover/Nature Chemistry/9_4.png,MAC_Bench/Nature/Cover/Nature Chemistry/9_4.png,vith,9_4.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_3.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_3.png,groundtruth,16_3.txt,train
Journal of the American Chemical Society,2024_27,Which of the following options best describe the cover story?,A novel carbene-assisted strategy for arene ring-opening is demonstrated. Experiments and DFT calculations have validated that both diazo and non-diazo carbene precursors could effectively initiate the reactions to afford value-added extended conjugated molecules. This chemistry expands the horizons of carbene chemistry and provides a novel pathway for arene ring-opening.,A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_27.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_27.png,groundtruth,2024_27.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_27.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_27.png,vith,2010_27.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,vitg,2010_30.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2020_37.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2020_37.png,clip,2020_37.txt,train
Joule,8_3,Which of the following options best describe the cover story?,"On the cover: The cover image features an all-solid-state battery (ASSB) incorporating
an FeSn2 anode, a LiNi0.6Co0.2Mn0.2O2 (NCM622) cathode, and a Li6PS5Cl solid electrolyte placed on an electronic circuit. The continents of the Earth
are illuminated by the energy generated from this high-energy-density ASSB, symbolizing
its potential to revolutionize global energy storage and utilization. As demonstrated
by Lee et al., this ASSB exhibits exceptional performance, stability, and energy efficiency, emphasizing
its crucial role in advancing sustainable energy for the future. This pioneering research
highlights the potential of FeSn2 anodes to enhance the overall performance and safety of ASSBs, driving innovation
in energy storage technology. Artist/image source: Suk-Woo Yoon (SCIART 3D GRAPHIC
in Republic of Korea).",A,MAC_Bench/Cell/Cover/Joule/8_3.png,MAC_Bench/Cell/Cover/Joule/8_3.png,groundtruth,8_3.txt,MAC_Bench/Cell/Cover/Joule/4_6.png,MAC_Bench/Cell/Cover/Joule/4_6.png,clip,4_6.txt,MAC_Bench/Cell/Cover/Joule/5_8.png,MAC_Bench/Cell/Cover/Joule/5_8.png,vitg,5_8.txt,MAC_Bench/Cell/Cover/Joule/2_6.png,MAC_Bench/Cell/Cover/Joule/2_6.png,vith,2_6.txt,train
Nature Plants,10_8,Which of the following options best describe the cover story?,"Generating gametangia
Bryophytes, such as the model liverwort Marchantia polymorpha, develop sexual organs known as gametangia. The ‘non-canonical’ transcription factor MpBZR3 is involved in regulating both male and female structures, antheridia and archegonia respectively. Overexpression of MpBZR3 induces ectopic development of multiple gametangia.
See Furuya et al.
Image: Tomoyuki Furuya, Ritsumeikan University. Cover design: Erin Dewalt",C,MAC_Bench/Nature/Cover/Nature Plants/9_2.png,MAC_Bench/Nature/Cover/Nature Plants/9_2.png,vith,9_2.txt,MAC_Bench/Nature/Cover/Nature Plants/5_3.png,MAC_Bench/Nature/Cover/Nature Plants/5_3.png,vitg,5_3.txt,MAC_Bench/Nature/Cover/Nature Plants/10_8.png,MAC_Bench/Nature/Cover/Nature Plants/10_8.png,groundtruth,10_8.txt,MAC_Bench/Nature/Cover/Nature Plants/4_6.png,MAC_Bench/Nature/Cover/Nature Plants/4_6.png,clip,4_6.txt,test
Biophysical Journal,124_3,Which of the following options best describe the cover story?,"Cover picture: Inhibition of the Brahma-related gene (BRG1) motor in the Brg/Brm-associated factor
chromatin remodeling complex stiffens the nucleus, preventing its transition from
an oblate shape in substrate-attached cells to a spherical shape in plasma-membrane-enclosed
karyoplasts upon isolation. When fibroblasts with active BRG1 are exposed to gentle
centrifugal forces, they lose most of their nuclei, leaving behind nucleus-free cytoplasts.
In contrast, when the BRG1 motor is inhibited (as shown in this image), the same centrifugal
force leaves behind mostly intact cells and fewer cytoplasts (actin cytoskeleton stained
in green), with their nuclei (blue) unable to emerge from the cell during the centrifugation process. DOI: https://doi.org/10.1016/j.bpj.2024.11.3322.",A,MAC_Bench/Cell/Cover/Biophysical Journal/124_3.png,MAC_Bench/Cell/Cover/Biophysical Journal/124_3.png,groundtruth,124_3.txt,MAC_Bench/Cell/Cover/Biophysical Journal/111_1.png,MAC_Bench/Cell/Cover/Biophysical Journal/111_1.png,vitg,111_1.txt,MAC_Bench/Cell/Cover/Biophysical Journal/112_10.png,MAC_Bench/Cell/Cover/Biophysical Journal/112_10.png,vith,112_10.txt,MAC_Bench/Cell/Cover/Biophysical Journal/101_11.png,MAC_Bench/Cell/Cover/Biophysical Journal/101_11.png,clip,101_11.txt,train
NATURE REVIEWS MICROBIOLOGY,22_8,Which of the following options best describe the cover story?,"Alternatives for treating antibiotic-resistant pathogens, inspired by the Review on p262.
Cover design: Philip Patenall.",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_8.png,ave_0,20_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_8.png,vith,19_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_8.png,groundtruth,22_8.txt,train
Cell Genomics,4_12,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Wu et al. present an innovative approach to non-invasively quantify extracellular RNA (exRNA)
extracted from the spent culture media of human in vitro fertilization (IVF) embryos. The cover art ingeniously captures the study's essence,
envisioning the temporal fluctuations of exRNA resembling majestic mountains while
depicting embryos as celestial stars. Crafted by Yuan Liu, this image encapsulates
the intricate interplay between exRNA dynamics and the developmental journey of embryos.",B,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,vitg,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,groundtruth,4_12.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,clip,3_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_3.png,MAC_Bench/Cell/Cover/Cell Genomics/4_3.png,vith,4_3.txt,val
Cell Systems,15_7,Which of the following options best describe the cover story?,"On the cover: Illustration showing simulations of tumor growth arranged as the two
strands of a DNA helix, shattered by the emblematic double strand break induced by
PARP inhibitors. The simulations (strands) compare two adaptive strategies: as the
tumor responds and regrows under treatment (blue lines), doses are either modulated
or skipped (shading and bars, with some artistic liberties). In this issue of Cell Systems, Strobl et al. integrate real-time microscopy and mathematical modeling to investigate whether adaptive
therapy, which dynamically tailors treatment to the tumor dynamics, could help to
reduce cumulative PARP inhibitor use to reduce toxicity. Image credit: Kit Gallagher
and the authors.",A,MAC_Bench/Cell/Cover/Cell Systems/15_7.png,MAC_Bench/Cell/Cover/Cell Systems/15_7.png,groundtruth,15_7.txt,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,vitg,4_4.txt,MAC_Bench/Cell/Cover/Cell Systems/1_3.png,MAC_Bench/Cell/Cover/Cell Systems/1_3.png,ave_2,1_3.txt,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,clip,1_5.txt,train
Nature Human Behaviour,8_3,Which of the following options best describe the cover story?,"Connecting humans and machines
The ubiquity of human–machine interactions is an opportunity to explore, while being mindful of the risks. This issue features a Focus on the many ways in which humans interact and communicate with machines, which foregrounds the societal implications and ethical considerations of emerging technologies.
See Focus
Image: Bethany Vukomanovic. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_11.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_11.png,ave_2,6_11.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_4.png,clip,7_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_3.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_3.png,groundtruth,8_3.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,vitg,4_2.txt,test
Science Advances,11_1,Which of the following options best describe the cover story?,"ONLINE COVER The crescent Earth rises above the lunar horizon in this photograph taken from the Apollo 17 spacecraft in lunar orbit during the final lunar landing mission in the Apollo program. The evolution of the lunar magnetic field helps explain the Moon’s interior structure, thermal history, and surface environment. Using mare basalt samples from the Moon’s Oceanus Procellarum at midlatitude, gathered from the Chang’e-5 mission, Cai et al. describe the existence of a weak lunar dynamo 2 billion years ago. Their findings also suggest an alternative mechanism for the origin of the young lunar volcanism. These details will help shape studies of lunar space weathering and volatile materials. Credit: NASA/JSC",D,MAC_Bench/Science/Cover/Science Advances/9_5.png,MAC_Bench/Science/Cover/Science Advances/9_5.png,clip,9_5.txt,MAC_Bench/Science/Cover/Science Advances/10_4.png,MAC_Bench/Science/Cover/Science Advances/10_4.png,vitg,10_4.txt,MAC_Bench/Science/Cover/Science Advances/9_27.png,MAC_Bench/Science/Cover/Science Advances/9_27.png,vith,9_27.txt,MAC_Bench/Science/Cover/Science Advances/11_1.png,MAC_Bench/Science/Cover/Science Advances/11_1.png,groundtruth,11_1.txt,train
Matter,7_4,Which of the following options best describe the cover story?,"On the cover: This month's cover from Hsu and colleagues depicts a red-colored biomaterials film wrapped in a spiral pattern to look like
a rose, sitting in a menstrual cup. The work describes the development of an eco-friendly,
blood-absorbent biomaterial that improves the performance of menstrual products by
minimizing blood leakage and spilling while also helping to prevent infection. The
stark cover counters the stigma of thinking or studying menstruation, using advanced
functional materials for innovative solutions. Image courtesy of the authors.",B,MAC_Bench/Cell/Cover/Matter/6_2.png,MAC_Bench/Cell/Cover/Matter/6_2.png,vith,6_2.txt,MAC_Bench/Cell/Cover/Matter/7_4.png,MAC_Bench/Cell/Cover/Matter/7_4.png,groundtruth,7_4.txt,MAC_Bench/Cell/Cover/Matter/7_3.png,MAC_Bench/Cell/Cover/Matter/7_3.png,clip,7_3.txt,MAC_Bench/Cell/Cover/Matter/3_2.png,MAC_Bench/Cell/Cover/Matter/3_2.png,vitg,3_2.txt,train
ACS Earth and Space Chemistry,2024_6,Which of the following options best describe the cover story?,"Wildfire particulate matter is comprised of a complex mixture of chemical species such as organic carbon (OC), elemental carbon (EC), ions, polycyclic aromatic hydrocarbons (PAHs), and metals. Prevailing winds can transport fresh plumes to urban centers thousands of kilometers away from the burning site, and secondary processing may change the chemical composition during transport.",B,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_11.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_11.png,vitg,2022_11.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_6.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,ave_1,2024_10.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_10.png,clip,2022_10.txt,train
Developmental Cell,59_12,Which of the following options best describe the cover story?,"On the cover: These confocal images of Drosophila larval salivary gland nuclei show the distinctive banding pattern of the large, highly
polytene chromosomes (stained with Hoechst in magenta and orange). Chromatin status
is visualised using antibodies for Histone 3 lysine 4 tri-methylation (cyan). The
large size of these nuclei makes them ideal for studying transcription factor behavior.
To learn more about the biophysical behaviour of transcription effectors of the Hippo
pathway, see Manning et al. Image credit: Samuel Manning.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_12.png,MAC_Bench/Cell/Cover/Developmental Cell/59_12.png,groundtruth,59_12.txt,MAC_Bench/Cell/Cover/Developmental Cell/40_4.png,MAC_Bench/Cell/Cover/Developmental Cell/40_4.png,vith,40_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/56_10.png,MAC_Bench/Cell/Cover/Developmental Cell/56_10.png,clip,56_10.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_7.png,MAC_Bench/Cell/Cover/Developmental Cell/59_7.png,vitg,59_7.txt,train
Trends in Plant Science,29_10,Which of the following options best describe the cover story?,"An in-depth analysis of the mechanistic processes underlying the evolution and ecophysiology
of typical invasive plants such as Carpobrotus spp., Acacia spp., Agave spp. and Opuntia spp. (shown on the cover) in Mediterranean-type ecosystems shows very sophisticated,
complex, and efficient strategies for invasion success, particularly in fragmented
habitats. Sergi Munné-Bosch proposes a two-pronged strategy based on long-term prevention
and eradication for the management of Mediterranean-type ecosystems. Image credit:
Sergi Munné-Bosch.",A,MAC_Bench/Cell/Cover/Trends in Plant Science/29_10.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_10.png,groundtruth,29_10.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/22_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/22_1.png,ave_2,22_1.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/26_9.png,MAC_Bench/Cell/Cover/Trends in Plant Science/26_9.png,clip,26_9.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/26_5.png,MAC_Bench/Cell/Cover/Trends in Plant Science/26_5.png,vitg,26_5.txt,val
Nature Reviews Endocrinology,20_6,Which of the following options best describe the cover story?,"The individual response to antibiotics and diet, inspired by the Review on p387.
Cover design: Jennie Vallis",A,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_6.png,groundtruth,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_2.png,ave_2,17_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,clip,19_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,vith,18_12.txt,train
Nature Food,5_12,Which of the following options best describe the cover story?,"Urban agriculture
Urban food systems still rely almost entirely on imported goods and services. The acceleration of urbanization is therefore expected to place greater demands on resources that are already strained by shifting land use, rising inequalities and climate change. Urban agriculture represents a promising lever to reduce this pressure while inducing a broader transformative change towards urban resilience and sustainability. Scaling up urban agriculture will need to address diversity, heterogeneity, connectivity, spatial synergies and trade-offs, nonlinearity, scale and polycentricity. This transition could prompt the decentralization of urban food supplies, bolster ecosystem services, mitigate transboundary environmental footprints and advance urban resilience. Multi-phase developmental pathways, including dynamics, accelerators and feedback associated with scaling up urban agriculture, should be considered in support of food security for the growing urban population.
See Qiu et al.
Image: Lim Weixiang - Zeitgeist Photos/E+/Getty. Cover Design: Tulsi Voralia.",C,MAC_Bench/Nature/Cover/Nature Food/3_11.png,MAC_Bench/Nature/Cover/Nature Food/3_11.png,ave_3,3_11.txt,MAC_Bench/Nature/Cover/Nature Food/2_7.png,MAC_Bench/Nature/Cover/Nature Food/2_7.png,vitg,2_7.txt,MAC_Bench/Nature/Cover/Nature Food/5_12.png,MAC_Bench/Nature/Cover/Nature Food/5_12.png,groundtruth,5_12.txt,MAC_Bench/Nature/Cover/Nature Food/3_4.png,MAC_Bench/Nature/Cover/Nature Food/3_4.png,clip,3_4.txt,train
Nature Geoscience,17_11,Which of the following options best describe the cover story?,"Emergence of the Antarctic Circumpolar Current
Ocean sediment records indicate that the modern Antarctic Circumpolar Current did not exist prior to climatic cooling in the Late Miocene, suggesting an origin linked to the expansion of the Antarctic Ice Sheet. The image shows Spanish polar research vessel BIO Hespérides (A-33) offshore Livingston Island in the South Shetlands Archipelago, Antarctic Peninsula.
See Evangelinos et al.
Image: José-Abel Flores, University of Salamanca. Cover Design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/9_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/9_7.png,vith,9_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/14_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_7.png,clip,14_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_11.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_11.png,groundtruth,17_11.txt,MAC_Bench/Nature/Cover/Nature Geoscience/6_11.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_11.png,ave_2,6_11.txt,train
ACS Chemical Neuroscience,2024_12,Which of the following options best describe the cover story?,ᴅ-glucose ([18F]FDG) PET imaging. [18F]FDG PET offers a quantitative and translational neuroimaging method to explore the CNS effects of candidate drugs for smoking cessation therapy.,A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_12.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_11.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_11.png,vitg,2020_11.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_15.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_15.png,vith,2024_15.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_13.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_13.png,clip,2022_13.txt,train
Molecular Pharmaceutics,2024_7,Which of the following options best describe the cover story?,Schematic graphical representation of multiple drug substances interacting inside a phospholipid bilayer while permeating from a liposome.,C,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_6.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_6.png,clip,2022_6.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_12.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_12.png,vitg,2024_12.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_7.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,ave_0,2020_4.txt,train
ACS Photonics,2024_6,Which of the following options best describe the cover story?,"An intelligent meta-device with a stereo vision meta-lens can provide a multimodal assisted driving vision by integrating the raw image, instance labels, bounding boxes, segmentation masks in depth pseudo color, and depth information for each detected object.",B,MAC_Bench/ACS/Cover/ACS Photonics/2024_10.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Photonics/2024_6.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Photonics/2020_3.png,MAC_Bench/ACS/Cover/ACS Photonics/2020_3.png,clip,2020_3.txt,MAC_Bench/ACS/Cover/ACS Photonics/2021_12.png,MAC_Bench/ACS/Cover/ACS Photonics/2021_12.png,vith,2021_12.txt,train
Nature Reviews Psychology,3_5,Which of the following options best describe the cover story?,"In this Review, Bell et al. describe current VR-based treatments for mental health conditions and discuss technological and psychological tools that might promote enhanced immersive experiences.
Cover design: David Johnston",C,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_6.png,ave_2,1_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_5.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_5.png,groundtruth,3_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_9.png,vitg,1_9.txt,train
ACS Applied Engineering Materials,2024_1,Which of the following options best describe the cover story?,"The ACS AMI Family “2024 Early Career Forum” highlights groundbreaking research and innovative ideas from the emerging authors in the scientific community on a broad range of topics. This edition of the Forum showcases 135 exceptional contributions from early-career scientists worldwide, published across ACS Applied Materials & Interfaces, ACS Applied Bio Materials, ACS Applied Electronic Materials, ACS Applied Engineering Materials, ACS Applied Energy Materials, ACS Applied Nano Materials, ACS Applied Optical Materials, and ACS Applied Polymer Materials.",C,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,clip,2024_12.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_10.png,ave_1,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,vith,2023_12.txt,train
Caner Cell,42_12,Which of the following options best describe the cover story?,"On the cover: Routy et al. review the microbiota research in the context of melanoma. The cover image demonstrates
the interplay between melanoma cancer cells and microbiota visually. An intricate
network of lines creates connections that symbolize the link between intestinal bacteria
and melanoma, highlighting the recent research included in the content, visually showcasing
the intricate relationship between the two. Image credit: Simon Rohlen, known as KEF!.",B,MAC_Bench/Cell/Cover/Caner Cell/23_5.png,MAC_Bench/Cell/Cover/Caner Cell/23_5.png,vitg,23_5.txt,MAC_Bench/Cell/Cover/Caner Cell/42_12.png,MAC_Bench/Cell/Cover/Caner Cell/42_12.png,groundtruth,42_12.txt,MAC_Bench/Cell/Cover/Caner Cell/21_3.png,MAC_Bench/Cell/Cover/Caner Cell/21_3.png,clip,21_3.txt,MAC_Bench/Cell/Cover/Caner Cell/30_5.png,MAC_Bench/Cell/Cover/Caner Cell/30_5.png,ave_1,30_5.txt,train
Current Biology,34_13,Which of the following options best describe the cover story?,"On the cover: A juvenile male rufous hummingbird (Selasphorus rufus) midflight in Vancouver, British Columbia. In this issue, Gaede et al. describe neural responses to tactile stimuli, including gusts of air, that may contribute
to the remarkable aerial abilities of hummingbirds. Using in vivo physiology in hummingbirds and finches, the authors reveal two distinct three-dimensional
maps in the avian forebrain that process touch, including areas corresponding to the
wings. Photograph by Duncan Leitch.",B,MAC_Bench/Cell/Cover/Current Biology/25_2.png,MAC_Bench/Cell/Cover/Current Biology/25_2.png,ave_2,25_2.txt,MAC_Bench/Cell/Cover/Current Biology/34_13.png,MAC_Bench/Cell/Cover/Current Biology/34_13.png,groundtruth,34_13.txt,MAC_Bench/Cell/Cover/Current Biology/20_22.png,MAC_Bench/Cell/Cover/Current Biology/20_22.png,vitg,20_22.txt,MAC_Bench/Cell/Cover/Current Biology/30_11.png,MAC_Bench/Cell/Cover/Current Biology/30_11.png,clip,30_11.txt,test
ACS Macro Letters,2024_10,Which of the following options best describe the cover story?,The more stretched bridging blocks and higher network connectivity in the self-assembled structure by the ABA triblock copolymer enable its superior mechanical performance over that by the ABC counterpart with a higher fraction of bridging block. Image Courtesy of Weihua Li.,B,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_9.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_9.png,vitg,2023_9.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_10.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2013_1.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2013_1.png,vith,2013_1.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_8.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_8.png,clip,2023_8.txt,train
Cancer Cell,42_2,Which of the following options best describe the cover story?,"On the cover: In their review, Galluzzi and colleagues examine the mechanisms by which malignant cells evade immune elimination through
a novel “three Cs” framework. Camouflage refers to cancer cells’ ability to disguise themselves from the immune system,
preventing recognition as a threat. Coercion involves the direct or indirect inhibition of immune functions by neoplastic
cells, while cytoprotection describes the capacity of malignant cells to withstand cytotoxic agents.
Together, these strategies contribute to immunoevasion and resistance to (immuno)therapy
across various oncological contexts.",C,MAC_Bench/Cell/Cover/Cancer Cell/20_1.png,MAC_Bench/Cell/Cover/Cancer Cell/20_1.png,vitg,20_1.txt,MAC_Bench/Cell/Cover/Cancer Cell/23_2.png,MAC_Bench/Cell/Cover/Cancer Cell/23_2.png,vith,23_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_2.png,MAC_Bench/Cell/Cover/Cancer Cell/42_2.png,groundtruth,42_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/40_3.png,MAC_Bench/Cell/Cover/Cancer Cell/40_3.png,clip,40_3.txt,train
Accounts of Chemical Research,2024_18,Which of the following options best describe the cover story?,"organic frameworks (2D c-MOFs) have emerged as a class of graphene-like materials with fully π-conjugated aromatic structures. Designing novel ligands is essential for the construction of new 2D c-MOFs with high crystallinity, excellent conductivity, and tailor-made functions.",B,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_17.png,vitg,2021_17.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_18.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_18.png,groundtruth,2024_18.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_7.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_7.png,vith,2019_7.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,clip,2024_17.txt,val
Lab Animal,54_1,Which of the following options best describe the cover story?,"Exploring the effects of electrical stunning on zebrafish larvae
Available methods for zebrafish euthanasia have limitations. In a new Article, Burkhardt et al. investigated the behavioral and neurophysiological effects of electrical stunning on zebrafish larvae, showing that rapid and reliable euthanasia can be achieved with this method.
See Burkhardt et al.
Cover image: Marina Spence. Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Lab Animal/48_5.png,MAC_Bench/Nature/Cover/Lab Animal/48_5.png,vitg,48_5.txt,MAC_Bench/Nature/Cover/Lab Animal/48_2.png,MAC_Bench/Nature/Cover/Lab Animal/48_2.png,ave_1,48_2.txt,MAC_Bench/Nature/Cover/Lab Animal/54_1.png,MAC_Bench/Nature/Cover/Lab Animal/54_1.png,groundtruth,54_1.txt,MAC_Bench/Nature/Cover/Lab Animal/52_1.png,MAC_Bench/Nature/Cover/Lab Animal/52_1.png,clip,52_1.txt,train
Journal of Chemical Theory and Computation,2024_17,Which of the following options best describe the cover story?,"The extension of the Martini forcefield to glycosaminoglycans (GAGs, shown in red) enables coarse-grained simulation of more representative biological systems, such as the surface of cell membranes (yellow, green) where various proteoglycans and GAG-binding receptors (blue) are depicted.",C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_7.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_7.png,vith,2022_7.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2018_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2018_12.png,clip,2018_12.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,vitg,2021_12.txt,test
Trends in Parasitology,41_1,Which of the following options best describe the cover story?,"The cover is the official logo of the 32nd National Congress of Parasitology
(NCP), Pune. The conference logo is inspired by Warli folk art, a tribal art originating
from
the Sahyadri range in Maharashtra, India. The logo is the visual representation of
the
theme of the conference, the impact of parasitic infections and vectors on both humans
and animals, with a One Health emphasis, and the need to take a holistic approach
to eliminate the burden of parasitic infections. In this issue of Trends in Parasitology,
Purkayastha et al. highlight the proceedings from the conference, which brought together
eminent parasitologists from India and also Africa to present and discuss their exciting
research from the field. Image credit: originally designed by Sindhuri Upadrasta and
further developed and digitally rendered by D.V. Mamatharani.",C,MAC_Bench/Cell/Cover/Trends in Parasitology/31_10.png,MAC_Bench/Cell/Cover/Trends in Parasitology/31_10.png,vith,31_10.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/35_12.png,MAC_Bench/Cell/Cover/Trends in Parasitology/35_12.png,clip,35_12.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/41_1.png,MAC_Bench/Cell/Cover/Trends in Parasitology/41_1.png,groundtruth,41_1.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/38_8.png,MAC_Bench/Cell/Cover/Trends in Parasitology/38_8.png,vitg,38_8.txt,train
Nature Food,5_4,Which of the following options best describe the cover story?,"Culturally acceptable diets
The EAT–Lancet reference diet provides guidance on how to simultaneously achieve environmental goals and improve human health. Yet, its wide-scale adoption requires attention to the cultural preferences and values of different populations around the world. In China, an ethnically and geographically diverse country, eating habits vary widely. A newly proposed region-specific reference diet aligned with local culinary traditions and preferences can reduce the environmental impact of food consumption and promote health beyond what would be achieved by adhering to other official dietary guidelines.
See Liu et al.
Image: wulingyun/Moment/Getty. Cover design: Laoise Mac Gabhann",D,MAC_Bench/Nature/Cover/Nature Food/2_10.png,MAC_Bench/Nature/Cover/Nature Food/2_10.png,clip,2_10.txt,MAC_Bench/Nature/Cover/Nature Food/3_4.png,MAC_Bench/Nature/Cover/Nature Food/3_4.png,vitg,3_4.txt,MAC_Bench/Nature/Cover/Nature Food/4_7.png,MAC_Bench/Nature/Cover/Nature Food/4_7.png,vith,4_7.txt,MAC_Bench/Nature/Cover/Nature Food/5_4.png,MAC_Bench/Nature/Cover/Nature Food/5_4.png,groundtruth,5_4.txt,train
Trends in Biochemical Sciences,49_11,Which of the following options best describe the cover story?,"The aberrant accumulation of amyloid structures is the underlying cause
of severe human diseases. However, the amyloid fold also plays a role in executing
specific biological functions. In the pages 119−133 of this issue, Garcia-Pardo and
Ventura discuss how the recent cryo-EM resolution revolution has enabled deciphering
the molecular intricacies of ribonucleoprotein amyloids, providing clues to rationalize
the dual involvement of this fold in normal protein function and disease pathology.
The cover art was designed by Dr. Javier Garcia-Pardo (@J_GarciaPardo) and Prof.
Dr. Salvador Ventura, and showcases a human brain, assembled from cryo-EM map
sections of hnRNPDL-2 amyloid fibrils (PDB 7ZIR) (@PPMC_UAB). Image from Ella
Maru Studio (@Ella_Maru).",B,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_1.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_1.png,clip,40_1.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_11.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_11.png,groundtruth,49_11.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_7.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_7.png,vith,45_7.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,vitg,47_14.txt,test
Science Translational Medicine,17_783,Which of the following options best describe the cover story?,"ONLINE COVER Manipulating Mitochondrial DNA. The cover shows a cross-section of a skeletal muscle fiber stained for cytochrome c oxidase activity (dark brown), an indicator of mitochondrial function, in a mouse treated with a mitochondrial DNA (mtDNA) base editor to correct a mutation in a mitochondrial tRNA. Mitochondrial disorders are often caused by mutations in mtDNA that are difficult to correct with traditional gene editing. Barrera-Paez et al. used a dose-dependent mitochondrial DddA-derived cytosine base editor (DdCBE) to successfully correct a mitochondrial tRNA mutation in mouse heart and muscle. However, at the highest doses of editing, DdCBE induced off-target DNA edits resulting in severe adverse effects in the mice. Together, the results suggest that DdCBE is a promising tool for mitochondrial gene editing, but caution is required to avoid dose-dependent adverse effects. Credit: Jose Domingo Barrera-Paez",B,MAC_Bench/Science/Cover/Science Translational Medicine/5_185.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_185.png,vitg,5_185.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_783.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_783.png,groundtruth,17_783.txt,MAC_Bench/Science/Cover/Science Translational Medicine/2_15.png,MAC_Bench/Science/Cover/Science Translational Medicine/2_15.png,clip,2_15.txt,MAC_Bench/Science/Cover/Science Translational Medicine/9_408.png,MAC_Bench/Science/Cover/Science Translational Medicine/9_408.png,vith,9_408.txt,train
ACS Sensors,2024_8,Which of the following options best describe the cover story?,"Rich surface oxygen vacancies play the role of active sites for adsorption of NO2 molecules, and the Schottky junctions effectively adjust the charge transfer behavior through the conduction tunnel in the sensing material. Furthermore, In2O3 nanoparticles almost fully cover the",A,MAC_Bench/ACS/Cover/ACS Sensors/2024_8.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Sensors/2016_11.png,MAC_Bench/ACS/Cover/ACS Sensors/2016_11.png,vitg,2016_11.txt,MAC_Bench/ACS/Cover/ACS Sensors/2023_7.png,MAC_Bench/ACS/Cover/ACS Sensors/2023_7.png,vith,2023_7.txt,MAC_Bench/ACS/Cover/ACS Sensors/2019_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2019_4.png,clip,2019_4.txt,train
ACS Infectious Diseases,2024_3,Which of the following options best describe the cover story?,"Background image generated by Abdulmujeeb Onawole using DALL·E with the prompt “silhouette of an investigator with a deerstalker hat and a magnifying glass, surrounded by bacteria and floating pills”, with superimposed structures of a range of novel antibiotics that act on new bacterial targets.",C,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_7.png,clip,2020_7.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2019_5.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2019_5.png,ave_3,2019_5.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_3.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_9.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_9.png,vitg,2018_9.txt,train
Nature Synthesis,3_12,Which of the following options best describe the cover story?,"MOFs made to order
The synthesis of isoreticular zeolite-like MOFs is achieved using a face-directed assembly strategy inspired by architecture techniques. The strategy combines a supermolecular building block approach with the use of various centring structure-directing agents.
See Barsukova et al.
Image: Aleksandr Sapianik. Cover design: Amie Fernandez",A,MAC_Bench/Nature/Cover/Nature Synthesis/3_12.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_12.png,groundtruth,3_12.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,vitg,2_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_6.png,clip,1_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,ave_1,3_1.txt,val
Industrial & Engineering Chemistry Research,2024_29,Which of the following options best describe the cover story?,A mathematical model has been developed based on boundary-forming points in a solid–solid–liquid ternary phase diagram for tie-line prediction.,A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_29.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_29.png,groundtruth,2024_29.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_2.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_2.png,clip,2022_2.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_17.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_17.png,vitg,2021_17.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_10.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_10.png,vith,2022_10.txt,val
NATURE REVIEWS MICROBIOLOGY,22_3,Which of the following options best describe the cover story?,"Tackling bacterial antimicrobial resistance, inspired by the Focus issue.
Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_8.png,ave_2,20_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_3.png,groundtruth,22_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_8.png,vith,19_8.txt,train
Trends in Microbiology,32_8,Which of the following options best describe the cover story?,"Nitrogen (N) is absolutely essential to life as we know it. Though
atmospherically abundant, N must first be converted, or “fixed,” prior to biological
uptake
and crop fertilizer manufacturing. Synthetic N-fixation, today responsible for half
of all fixed
N, comes with profound economic and environmental costs. Fortunately, an alternative,
ancient biological strategy—catalyzed by microbially hosted nitrogenase proteins—holds
enormous bioengineering potential for sustainable N-fixation. Yet, researchers have
been
unable to mimic this elegant biological solution and lack an understanding of environmental
drivers in its evolution, limiting predictions for how biological N-fixation will
respond to a
changing climate. In this special issue, Holly Rucker and Betül Kaçar review the complex
history of nitrogen fixation over billions of years of planetary history.
Image courtesy: Prof. Betül Kaçar, UW-Madison.",D,MAC_Bench/Cell/Cover/Trends in Microbiology/19_8.png,MAC_Bench/Cell/Cover/Trends in Microbiology/19_8.png,vitg,19_8.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/23_5.png,MAC_Bench/Cell/Cover/Trends in Microbiology/23_5.png,vith,23_5.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/21_1.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_1.png,clip,21_1.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_8.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_8.png,groundtruth,32_8.txt,train
Accounts of Materials Research,2024_9,Which of the following options best describe the cover story?,"Sunscreens are used to protect the skin from ultraviolet radiation (UVR)-induced carcinogenic effects on mammalian skin. Many sunscreens harness the UVR absorbing properties of ZnO and TiO2, which results in a white film left on the skin. Factors contributing to white cast include particle size, polymeric dispersion, and surface treatment of the ZnO and TiO2 used in sunscreens. This Viewpoint provides a physicochemical framework for best practices in standardizing the white cast potential of sunscreen formulations with metal oxide UVR filters.",B,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_9.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_9.png,clip,2023_9.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_9.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_11.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_11.png,ave_2,2024_11.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_7.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_7.png,ave_3,2022_7.txt,train
Nature Cities,1_5,Which of the following options best describe the cover story?,"Cooling from natural areas
Overheating of cities is an increasing problem. Cao et al. investigate how neighboring rural land cover can mitigate and absorb urban heat.
See Yang et al.
Image: Shijie Cao, Southeast University, China. Cover design: Lauren Heslop.",C,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,vith,1_11.txt,MAC_Bench/Nature/Cover/Nature Cities/1_1.png,MAC_Bench/Nature/Cover/Nature Cities/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,groundtruth,1_5.txt,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,vitg,1_2.txt,train
Trends in Immunology,45_3,Which of the following options best describe the cover story?,"Our special issue on ‘Neuroimmunology – II’ presents current research
in this discipline, highlighting the crosstalk between the immune and nervous systems
(central or peripheral). The micrograph on the cover shows an optical section through
a
dorsal root ganglion (green) taken from an MHC-II I–Abβ-eGFP reporter mouse at steady
state. The neurons (red) are stained with anti-β3-tubulin antibody (AF568) and the
nuclei
(blue) with DAPI. The image was acquired using a laser-scanning confocal microscope
at 20x magnification, and digitally upscaled using Topaz Gigapixel AI software. Image
credit: Pavel Hanc and Ulrich von Andrian.",A,MAC_Bench/Cell/Cover/Trends in Immunology/45_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_3.png,groundtruth,45_3.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,ave_1,36_4.txt,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,vitg,39_14.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,clip,36_3.txt,test
Trends in Chemistry,6_4,Which of the following options best describe the cover story?,"Light emitting diodes (LEDs) have revolutionized display technology
in our daily devices by efficiently converting electrical energy into light, with
organic
LEDs (OLEDs) being the most ubiquitous. For chemists, the emitter molecules
themselves hold the most interest, with properties that can be readily fine-tuned
to
unlock a diverse range of vibrant colours. In their review, Fan, Yuan and co-workers
explore recent advances in narrow-bandwidth carbon-based emitters (CBEs) including
small molecules, polymers, and carbon dots, with a focus on the relationship between
molecular structure and optical properties. CBE-based LEDs could hold great potential
as an efficient and widely adopted display technology for next-generation wide-color-gamut
displays. Cover credit: GettyImages/Yuanyuan Yan",A,MAC_Bench/Cell/Cover/Trends in Chemistry/6_4.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_4.png,groundtruth,6_4.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_13.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_13.png,ave_3,6_13.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/4_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_5.png,vith,4_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,clip,5_9.txt,train
Nature Neuroscience,27_5,Which of the following options best describe the cover story?,"Special issue on glia
Communication between glial cells has a profound effect on the pathophysiology of Alzheimer’s disease. Huang et al. report that reactive astrocytes impose cell distancing in peri-plaque glial nets via the guidance receptor Plexin-B1, which affects microglial access and compaction of amyloid plaques. The cover art depicts a fishing net catching fish, which symbolizes glial nets surrounding amyloid deposits in Alzheimer’s disease.
See Huang et al.
Image: Lily Armstrong-Davies, Mount Sinai Health Systems. Cover design: Marina Spence.",A,MAC_Bench/Nature/Cover/Nature Neuroscience/27_5.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_5.png,groundtruth,27_5.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/7_6.png,MAC_Bench/Nature/Cover/Nature Neuroscience/7_6.png,vitg,7_6.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/24_10.png,MAC_Bench/Nature/Cover/Nature Neuroscience/24_10.png,vith,24_10.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/12_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/12_2.png,clip,12_2.txt,test
Trends in Parasitology,41_2,Which of the following options best describe the cover story?,"The cover is the official logo of the 32nd National Congress of Parasitology
(NCP), Pune. The conference logo is inspired by Warli folk art, a tribal art originating
from
the Sahyadri range in Maharashtra, India. The logo is the visual representation of
the
theme of the conference, the impact of parasitic infections and vectors on both humans
and animals, with a One Health emphasis, and the need to take a holistic approach
to eliminate the burden of parasitic infections. In this issue of Trends in Parasitology,
Purkayastha et al. highlight the proceedings from the conference, which brought together
eminent parasitologists from India and also Africa to present and discuss their exciting
research from the field. Image credit: originally designed by Sindhuri Upadrasta and
further developed and digitally rendered by D.V. Mamatharani.",A,MAC_Bench/Cell/Cover/Trends in Parasitology/41_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/41_2.png,groundtruth,41_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/35_12.png,MAC_Bench/Cell/Cover/Trends in Parasitology/35_12.png,clip,35_12.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/31_10.png,MAC_Bench/Cell/Cover/Trends in Parasitology/31_10.png,vith,31_10.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/38_8.png,MAC_Bench/Cell/Cover/Trends in Parasitology/38_8.png,vitg,38_8.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_11,Which of the following options best describe the cover story?,"Extracellular targeted protein degradation, inspired by the Review on p126.
Cover design: S. Harris",A,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_11.png,groundtruth,23_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_1.png,clip,22_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_9.png,vith,21_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_6.png,vitg,20_6.txt,test
Nature Reviews Nephrology,20_8,Which of the following options best describe the cover story?,"Health outcomes associated with hydration status, inspired by the Review on p275.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,clip,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,vitg,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_12.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_12.png,vith,17_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_8.png,groundtruth,20_8.txt,train
NATURE REVIEWS GENETICS,25_3,Which of the following options best describe the cover story?,"Inspired by the Review on p698.
Cover design: Patrick Morgan",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_3.png,groundtruth,25_3.txt,train
Nature Reviews Nephrology,21_1,Which of the following options best describe the cover story?,"Targeting IgA nephropathy, inspired by the Review on p9
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_4.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_4.png,vitg,18_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,clip,17_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_2.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_2.png,ave_1,17_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/21_1.png,groundtruth,21_1.txt,test
Nature Neuroscience,28_2,Which of the following options best describe the cover story?,"Tau in AD extracellular vesicles
Brain extracellular vesicles (EVs) are thought to have a role in the clearance and spread of tau pathology in Alzheimer’s disease. However, the pathological tau species that are associated with EVs and how they contribute to clearance is unclear. Fowler, Behr and colleagues used electron cryo-tomography (cryo-ET) to image EVs from the brains of individuals with Alzheimer’s disease, directly visualizing the unexpected membrane-tethering of short tau filaments within EVs. The cover image represents the release of EVs containing membrane-tethered tau filaments from a neuron by blending the cryo-ET data with Gustav Klimt’s symbolist style.
See Fowler and Behr et al.
Image: Shraddha Nayak, VisLab, MRC Laboratory of Molecular Biology. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Nature Neuroscience/24_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/24_11.png,vith,24_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/17_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/17_9.png,vitg,17_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/14_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/14_9.png,clip,14_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/28_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/28_2.png,groundtruth,28_2.txt,test
The Journal of Physical Chemistry A,2025_6,Which of the following options best describe the cover story?,"This cover feature depicts the immobilization of a [Ru(bpy)2(nicotine)2](Cl)2 (Ru-nico) complex from the aqueous solution to a polymer film. The Ru-nico complex in aqueous solution and rigid media, such as poly(methyl-methacrylate) (PMMA) and polyacrylonitrile (PAN) polymer films, were subjected to ultrafast transient absorption and emission studies. The findings provide ligand dissociation dynamics of the Ru-nico complex as the nicotine ligand gradually detaches from the Ru ion in solution, whereas this dissociation is inhibited in polymer films. This restricted ligand dissociation in films results in an emissive and long-lived state of Ru-nico in comparison to a nonemissive and short-lived state in solution. Cover design by Mohini Semwal and Ratnadip De.",C,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_26.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_26.png,vitg,2024_26.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_12.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_12.png,vith,2024_12.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_6.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_5.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_5.png,clip,2024_5.txt,train
ACS Chemical Biology,2025_2,Which of the following options best describe the cover story?,"Fluorescently labeled neutrophils (green) migrate from the blood island toward a tissue lesion generated by irradiating a small area of the fish with light, causing the production of cytotoxic radicals via activation of a photolatent BAPO compound.",D,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_3.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_3.png,vitg,2024_3.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_4.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_4.png,vith,2015_4.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2021_2.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2021_2.png,clip,2021_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_2.png,groundtruth,2025_2.txt,train
Developmental Cell,59_16,Which of the following options best describe the cover story?,"On the cover: The cover displays three adult Drosophila optic lobes, each stained for a specific class of distal medulla neurons (top, Dm4;
middle, Dm1; bottom, Dm11) using multicolor stochastic labeling (MultiColor FlpOut,
or MCFO). In the accompanying paper, the authors show that each of these neurons is
born from neural stem cells derived from a specific larval subdomain within a patterned
neuroepithelium. The size of each domain of origin determines the abundance of each
specific neuronal type. Therefore, spatial patterning not only contributes to cell
fate specification but also regulates the stoichiometry of each neural class. To learn
more about how spatial patterning regulates neuronal cell fate in Drosophila, see Malin et al. Image credit: Jennifer Malin.",B,MAC_Bench/Cell/Cover/Developmental Cell/58_24.png,MAC_Bench/Cell/Cover/Developmental Cell/58_24.png,vitg,58_24.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_16.png,MAC_Bench/Cell/Cover/Developmental Cell/59_16.png,groundtruth,59_16.txt,MAC_Bench/Cell/Cover/Developmental Cell/30_1.png,MAC_Bench/Cell/Cover/Developmental Cell/30_1.png,vith,30_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/52_2.png,MAC_Bench/Cell/Cover/Developmental Cell/52_2.png,clip,52_2.txt,train
Nature Reviews Endocrinology,20_4,Which of the following options best describe the cover story?,"The relationship between the gut microbiota and thyroid disorders, inspired by the Review on p511.
Cover design: Jennie Vallis",C,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_6.png,ave_2,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,clip,19_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_4.png,groundtruth,20_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/15_3.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/15_3.png,ave_3,15_3.txt,train
Macromolecules,2024_12,Which of the following options best describe the cover story?,The combination of Suzuki-Catalyst-Transfer-Polymerization and preparative size-exclusion chromatography enables automated fractionation into a narrow-disperse polymer and true monodisperse oligomer batches using cost-effective low-pressure LC equipment!,D,MAC_Bench/ACS/Cover/Macromolecules/2018_3.png,MAC_Bench/ACS/Cover/Macromolecules/2018_3.png,vith,2018_3.txt,MAC_Bench/ACS/Cover/Macromolecules/2020_10.png,MAC_Bench/ACS/Cover/Macromolecules/2020_10.png,ave_0,2020_10.txt,MAC_Bench/ACS/Cover/Macromolecules/2013_4.png,MAC_Bench/ACS/Cover/Macromolecules/2013_4.png,clip,2013_4.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_12.png,MAC_Bench/ACS/Cover/Macromolecules/2024_12.png,groundtruth,2024_12.txt,train
Nature Reviews Materials,9_4,Which of the following options best describe the cover story?,"Developing vaccines for glioblastoma remains challenging owing to the immunosuppressive microenvironment of the tumour and the presence of the blood–brain barrier. Nanomaterials can be tailored to address the limitations of glioblastoma vaccination, potentially paving the way for important advancements. The cover illustrates these efforts through a brain outline superimposed on nanoparticles. See Hameedat F. et al.
Cover image: Flavia Cristina Moreira de Sousa. Cover design: David Johnston.",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_2.png,clip,8_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_11.png,vitg,9_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_1.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_1.png,vith,7_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_4.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_4.png,groundtruth,9_4.txt,train
Trends in Cognitive Sciences,28_9,Which of the following options best describe the cover story?,"Physical activity plays a significant role in various aspects of brain health
across the lifespan. However, the consequences of sedentary behavior (SB) are not
well understood. In this issue of Trends in Cognitive Sciences, Liye Zou and colleagues
summarize and discuss the evidence regarding SB's impact on brain health, including
its effects on cognitive performance, structural or functional brain measures, and
the
risk of dementia across different age groups. They critically evaluate different methods
for assessing SB and suggest new opportunities for using digital technology in these
assessments. The cover illustration features an anthropomorphic cartoon depicting
two
types of sedentary behavior (passive and active sedentary behaviors). Cover image
from Liye Zou.",D,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_4.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_4.png,clip,17_4.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/19_10.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/19_10.png,vitg,19_10.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/25_4.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/25_4.png,ave_1,25_4.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_9.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_9.png,groundtruth,28_9.txt,train
Chemical & Biomedical ImagingOpen Access,2025_2,Which of the following options best describe the cover story?,"This cover art represents the development of hyperspectral 3D stimulated Raman scattering microscopy (hyper-3D SRS) for studying lipid droplet (LD) dynamics during early embryogenesis. The illustration also highlights the spatial and chemical diversity of LDs within individual embryonic cells, revealing dynamic relationships between LD size and unsaturation levels as embryos develop. Sub-micrometer resolution and 3D optical sectioning capabilities of the hyper-3D SRS method uncover metabolic heterogeneity, showing its potential for clinical applications in the future.",B,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_2.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_6.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_6.png,ave_3,2023_6.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_3.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_3.png,clip,2023_3.txt,train
ACS Sensors,2024_5,Which of the following options best describe the cover story?,"Plasmonic hydrogen sensors are enhanced by using algorithms of phase space reconstruction and convolutional neural networks, achieving high accuracies, and significantly improving response speed, sensitivity, and the limit of detection. This work introduces safe, nonelectronic remote sensing, achieving 0.98 accuracy, with implications for advancing spectrum-based sensors.",D,MAC_Bench/ACS/Cover/ACS Sensors/2017_1.png,MAC_Bench/ACS/Cover/ACS Sensors/2017_1.png,clip,2017_1.txt,MAC_Bench/ACS/Cover/ACS Sensors/2023_2.png,MAC_Bench/ACS/Cover/ACS Sensors/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/ACS Sensors/2020_9.png,MAC_Bench/ACS/Cover/ACS Sensors/2020_9.png,vith,2020_9.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_5.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_5.png,groundtruth,2024_5.txt,val
Nature Reviews Electrical Engineering,2_1,Which of the following options best describe the cover story?,"High-resolution satellite sensors and artificial intelligence enable detailed tree monitoring at national and continental levels. The illustration depicts the results of the image processing of the data collected through tree mapping. See Brandt et al.
Image: Danish Agency for Data Supply and Infrastructure. Cover design: Sam Whitham.",A,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/2_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/2_1.png,groundtruth,2_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_3.png,ave_1,1_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,vitg,1_9.txt,test
Nature Reviews Rheumatology,20_6,Which of the following options best describe the cover story?,"Inspired by the Review on p399.
Cover design: Steven Hall",D,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_6.png,groundtruth,20_6.txt,train
Caner Cell,42_10,Which of the following options best describe the cover story?,"On the cover: Du et al. propose a staging model for EBV-related nasopharyngeal carcinoma (NPC) based on a
large multicenter cohort in China, demonstrating its superiority over the currently
used AJCC staging system. The cover image features traditional Chinese embroidery
art. The embroidered Great Wall symbolizes the resolve to conquer NPC, while the nine
beacon towers, arranged from afar to close by, represent the continuous evolution
and improvement of each edition of the staging system, from the first to the ninth
edition of AJCC Stage. The presence of pines and cranes symbolizes the safeguarding
of health. Bathed in sunlight, the emblematic representation encapsulates the journey
toward precision medicine and radiates a message of optimism for the future of NPC
treatment. Image credit: Jun Ma.",B,MAC_Bench/Cell/Cover/Caner Cell/35_5.png,MAC_Bench/Cell/Cover/Caner Cell/35_5.png,clip,35_5.txt,MAC_Bench/Cell/Cover/Caner Cell/42_10.png,MAC_Bench/Cell/Cover/Caner Cell/42_10.png,groundtruth,42_10.txt,MAC_Bench/Cell/Cover/Caner Cell/22_1.png,MAC_Bench/Cell/Cover/Caner Cell/22_1.png,ave_2,22_1.txt,MAC_Bench/Cell/Cover/Caner Cell/29_1.png,MAC_Bench/Cell/Cover/Caner Cell/29_1.png,vitg,29_1.txt,test
ACS Catalysis,2024_12,Which of the following options best describe the cover story?,"A mild photochemical etching strategy was designed to induce nitrogen vacancies at the center of heptazine rings over g-C3N4 holey nanosheets, which enhance CO2 photoreduction via delocalized π electron clouds with tunable electronic structures and mid-gap states.",C,MAC_Bench/ACS/Cover/ACS Catalysis/2023_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2023_11.png,clip,2023_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2020_14.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_14.png,vitg,2020_14.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_12.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2011_3.png,MAC_Bench/ACS/Cover/ACS Catalysis/2011_3.png,vith,2011_3.txt,train
Trends in Chemistry,6_5,Which of the following options best describe the cover story?,"Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for Part II continues on from Part I, highlighting some
of the
milestones and many paths taken on the 'great career race' for early-career scientists
today. Each running at their own pace, the authors in this special issue are all aiming
to innovate with an impact, solve real-world problems and become inspiring leaders
themselves. Artwork credit: Phillip Krzeminski",C,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,ave_2,6_8.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,clip,6_7.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,groundtruth,6_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,vith,6_6.txt,train
Matter,7_1,Which of the following options best describe the cover story?,"On the cover: The image presents an optimization landscape, with each local peak representing
a unique microstructure configuration. This visual concept aligns with Kench et al.'s recent paper, published in this issue, which outlines the application of generative
AI in mapping processing parameters to electrode microstructures, ultimately enhancing
cell performance. The landscape is depicted at sunrise, symbolizing the dawning of
a new era in materials design. Image courtesy of the authors.",C,MAC_Bench/Cell/Cover/Matter/2_6.png,MAC_Bench/Cell/Cover/Matter/2_6.png,vitg,2_6.txt,MAC_Bench/Cell/Cover/Matter/4_3.png,MAC_Bench/Cell/Cover/Matter/4_3.png,clip,4_3.txt,MAC_Bench/Cell/Cover/Matter/7_1.png,MAC_Bench/Cell/Cover/Matter/7_1.png,groundtruth,7_1.txt,MAC_Bench/Cell/Cover/Matter/2_2.png,MAC_Bench/Cell/Cover/Matter/2_2.png,ave_2,2_2.txt,train
Nature Ecology & Evolution,8_6,Which of the following options best describe the cover story?,"Name-calling
Desert Rose — the large female African elephant (Loxodonta africana) in the picture — produces a distress call that alerts her calves to danger, in Samburu Shaba National Reserve in northern Kenya. A study by Pardo et al. shows that individuals address conspecifics with name-like calls that do not rely on imitation of the receiver.
See Pardo et al.
Image: George Wittemyer. Cover Design: Allen Beattie.",D,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_8.png,vitg,2_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_1.png,clip,8_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_12.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_12.png,vith,8_12.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_6.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_6.png,groundtruth,8_6.txt,train
ACS Sustainable Chemistry & Engineering,2025_5,Which of the following options best describe the cover story?,"Ag-gCN nanocomposite catalysts were developed as copper-free alternatives for heterogeneous photocatalytic azide–alkyne cycloaddition reactions. The developed protocol shows a significant advancement in green chemistry, offering a sustainable, versatile, and efficient alternative for a broad range of substrates.",B,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_16.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_16.png,clip,2020_16.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_5.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2019_17.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2019_17.png,vitg,2019_17.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_10.png,ave_1,2021_10.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_10,Which of the following options best describe the cover story?,"Targeting hypoxia-inducible factors, inspired by the Review on p175.
Cover design: S. Harris",D,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,vitg,23_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_7.png,clip,23_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_6.png,vith,20_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_10.png,groundtruth,23_10.txt,test
Nature Cancer,5_7,Which of the following options best describe the cover story?,"Targeting tumor vascularization
De Palma and Hanahan outline the latest advances in understanding tumor angiogenesis and discuss therapeutic opportunities for targeting tumor vascularization.
See De Palma and Hanahan
Image: Mohammed Elamine ALIOUI / Alamy Stock Photo. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Cancer/3_6.png,MAC_Bench/Nature/Cover/Nature Cancer/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_4.png,MAC_Bench/Nature/Cover/Nature Cancer/4_4.png,vitg,4_4.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_7.png,MAC_Bench/Nature/Cover/Nature Cancer/5_7.png,groundtruth,5_7.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_3.png,MAC_Bench/Nature/Cover/Nature Cancer/4_3.png,ave_2,4_3.txt,train
ACS Applied Optical Materials,2024_6,Which of the following options best describe the cover story?,"In this invited paper, the authors developed new quantum-dot color conversion layers for micro-LED devices which could be applied to next-generation augmented reality displays",A,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,vitg,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_9.png,vith,2023_9.txt,val
The Journal of Organic Chemistry,2025_6,Which of the following options best describe the cover story?,"In an industrial setting, toluene oxidation products such as benzoic acid, benzaldehyde, and benzoate esters are crucial fine chemicals. Chemists are dedicated to preparing high-value chemical materials through green and simple oxidation technologies. This cover illustrates an aryl-halides-initiated photocatalytic strategy for the green and selective oxidation of toluene.",B,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2017_19.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2017_19.png,vith,2017_19.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_6.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2021_21.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2021_21.png,vitg,2021_21.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2021_18.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2021_18.png,clip,2021_18.txt,val
Accounts of Chemical Research,2024_12,Which of the following options best describe the cover story?,Membrane-spanning α-helical peptide pores for single-molecule sensing.,B,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2016_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2016_3.png,vith,2016_3.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_12.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_6.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_6.png,clip,2012_6.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_3.png,vitg,2015_3.txt,val
Industrial & Engineering Chemistry Research,2024_22,Which of the following options best describe the cover story?,"a) Summarized study methodology. b) Schematics related to the motivation of this study, which is controllable intelligent microfluidic nanoparticle synthesis. c) Overview of the research methods:",A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_22.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_30.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_30.png,vith,2020_30.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_48.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_48.png,vitg,2022_48.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_9.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_9.png,clip,2020_9.txt,train
Nature Nanotechnology,19_6,Which of the following options best describe the cover story?,"Switchable non-volatile topological devices
The cover image illustrates the ferroelectric hysteresis loop in doubly aligned magic-angle bilayer graphene. Applying an electric field to this heterostructure injects electrons into the ferroelectric graphene system non-volatilely, enabling quasi-continuous switchable ferroelectric states. This ferroelectricity coexists with the Chern insulator effect, enabling the selective switching of topologically protected quantum edge states, which can support noise-immune neuromorphic computing applications.
See Cheng et al.
Image: Chaoyang Zhao, independent artist; and Moyu Chen, Nanjing University. Cover design: Debbie Maizels.",D,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/7_11.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/7_11.png,vitg,7_11.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/6_7.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/6_7.png,ave_1,6_7.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_6.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_6.png,groundtruth,19_6.txt,train
Cell Metabolism,36_10,Which of the following options best describe the cover story?,"On the cover: Stress has a profound impact on gut disorders. In this issue of Cell Metabolism, Wei et al. reveal that psychological stress enriches gut microbial metabolite indole-3-acetate,
which disrupts intestinal stem cell differentiation and triggers epithelial injury.
The depiction of rolling clouds and stirring stars, inspired by Van Gogh’s masterpiece
The Starry Night, represents restless emotions in a person with depression. The broken ground and
castle along the winding river illustrate injured intestinal epithelia. The involvement
of microbes and the metabolite is represented as ants on the broken door. Cover art
by Xiao Zheng and Haiping Hao.",B,MAC_Bench/Cell/Cover/Cell Metabolism/37_1.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_1.png,ave_2,37_1.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png,groundtruth,36_10.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_7.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_7.png,clip,36_7.txt,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,vitg,37_2.txt,val
Nature Photonics,18_10,Which of the following options best describe the cover story?,"Quantum skyrmions
Two-photon entangled states with a non-trivial topology are used to form quantum skyrmions that exhibit topological invariance.
See Ornelas et al.
Image: Pedro Ornelas, University of the Witwatersrand. Cover Design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Photonics/18_10.png,MAC_Bench/Nature/Cover/Nature Photonics/18_10.png,groundtruth,18_10.txt,MAC_Bench/Nature/Cover/Nature Photonics/6_12.png,MAC_Bench/Nature/Cover/Nature Photonics/6_12.png,vith,6_12.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,clip,18_4.txt,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,vitg,6_11.txt,val
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_4,Which of the following options best describe the cover story?,"Designing clinical trials for alcohol use, inspired by the Consensus Statement on p626.
Cover design: Laura Marshall",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_6.png,ave_2,21_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_11.png,clip,20_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_11.png,ave_3,21_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_4.png,groundtruth,21_4.txt,test
Nature Reviews Physics,6_1,Which of the following options best describe the cover story?,"The cover of this issue illustrates the use of diamond sensors for many-body physics. See de Leon.
Image: Jared Rovny. Cover design: Susanne Harris.",A,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png,groundtruth,6_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,vith,4_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_10.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_10.png,vitg,4_10.txt,train
Trends in Pharmacological Sciences,45_2,Which of the following options best describe the cover story?,"Development of protective immune responses relies on a balance
between proinflammatory CD4 T helper (Th) cell populations such as Th17 cells and
regulatory CD4 T cells (Tregs) that keep immune activation in check. In this issue,
Kaul
and Schwartzberg discuss the role of interleukin-2–inducible T cell kinase (Itk),
which
controls the activation of phospholipase C gamma, Ca2+ influx and the activity of the
NFAT transcription factor, in regulating the balance between Th17 and Tregs. They
also explore the potential of inhibiting Itk as a therapeutic strategy for autoimmune
diseases. Dark pink/orange cells are Th17 cells with greater Itk activity and Ca2+ flux.
Light pink cell represents a Treg cell with decreased Itk activity and Ca2+ flux. Cover
art designed by Alexander Stewart, NIAID using Maxon Cinema4D Software.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/43_5.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/43_5.png,vitg,43_5.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_9.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_9.png,ave_2,42_9.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_2.png,groundtruth,45_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,clip,34_8.txt,train
NATURE REVIEWS MICROBIOLOGY,22_6,Which of the following options best describe the cover story?,"Targeting SARS-CoV-2, inspired by the Review on p391.
Cover design: Philip Patenall",B,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_10.png,clip,21_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_6.png,groundtruth,22_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,vitg,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_6.png,vith,19_6.txt,train
Organic Letters,2025_8,Which of the following options best describe the cover story?,"This cover art illustrates that when two coupling partners, ferrocene-p-tosylamides and allenes, were treated in the presence of Rh-catalyst, it led to the formation of two diastereodivergent [4+3] annulated ferrocene-p-tosylamides at two different temperatures, i.e., at room temperature (represented as moon in cover art) and at 60 °C (represented as sun in cover art). At room temperature, Rh-catalyzed [4+3] annulation selectively offered kinetically controlled diastereomer (>20:1 dr), whereas at 60 °C, a thermodynamically controlled diastereomer was obtained exclusively with >20:1 dr. This cover art has been designed by Sangit Kumar, Raviraj Ananda Thorat, and Raushan Kumar Jha. View the article.",C,MAC_Bench/ACS/Cover/Organic Letters/2023_5.png,MAC_Bench/ACS/Cover/Organic Letters/2023_5.png,vith,2023_5.txt,MAC_Bench/ACS/Cover/Organic Letters/2023_7.png,MAC_Bench/ACS/Cover/Organic Letters/2023_7.png,vitg,2023_7.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_8.png,MAC_Bench/ACS/Cover/Organic Letters/2025_8.png,groundtruth,2025_8.txt,MAC_Bench/ACS/Cover/Organic Letters/2022_43.png,MAC_Bench/ACS/Cover/Organic Letters/2022_43.png,clip,2022_43.txt,val
Lab Animal,54_2,Which of the following options best describe the cover story?,"Dietary effects across mouse life stages
Differences in standard chow diets can influence mouse model phenotypes and impact experimental reproducibility. In a new Article, Knuth et al. measured the phenotypic effects of exposing mice to commonly used standard chows during different life stages. Their findings demonstrate that the timing of diet exposure can also affect phenotypic outcomes.
See Knuth et al.
Cover image: Marina Spence. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Lab Animal/53_2.png,MAC_Bench/Nature/Cover/Lab Animal/53_2.png,clip,53_2.txt,MAC_Bench/Nature/Cover/Lab Animal/52_2.png,MAC_Bench/Nature/Cover/Lab Animal/52_2.png,vitg,52_2.txt,MAC_Bench/Nature/Cover/Lab Animal/53_7.png,MAC_Bench/Nature/Cover/Lab Animal/53_7.png,ave_3,53_7.txt,MAC_Bench/Nature/Cover/Lab Animal/54_2.png,MAC_Bench/Nature/Cover/Lab Animal/54_2.png,groundtruth,54_2.txt,train
Science Signaling,2007_411,Which of the following options best describe the cover story?,"COVER This week features a  Perspective on neurotrophic factors as a possible approach to the therapy of Parkinson's disease and other neurodegenerative disorders. The image depicts a brain. [Image: Christopher Bickel, AAAS]",D,MAC_Bench/Science/Cover/Science Signaling/2_79.png,MAC_Bench/Science/Cover/Science Signaling/2_79.png,vitg,2_79.txt,MAC_Bench/Science/Cover/Science Signaling/7_311.png,MAC_Bench/Science/Cover/Science Signaling/7_311.png,vith,7_311.txt,MAC_Bench/Science/Cover/Science Signaling/17_841.png,MAC_Bench/Science/Cover/Science Signaling/17_841.png,clip,17_841.txt,MAC_Bench/Science/Cover/Science Signaling/2007_411.png,MAC_Bench/Science/Cover/Science Signaling/2007_411.png,groundtruth,2007_411.txt,train
iScience,27_9,Which of the following options best describe the cover story?,"On the cover: People's vision for a future electricity system is decentralized, willing
to accept trade-offs, as shown in Mey et al. The picture captures this future vision with a person walking toward a small-scale
wind farm (six turbines) in the vicinity of several villages and settlements in central
Germany. Image credit: Lech Aleksandrowicz.",D,MAC_Bench/Cell/Cover/iScience/25_1.png,MAC_Bench/Cell/Cover/iScience/25_1.png,ave_3,25_1.txt,MAC_Bench/Cell/Cover/iScience/28_2.png,MAC_Bench/Cell/Cover/iScience/28_2.png,ave_2,28_2.txt,MAC_Bench/Cell/Cover/iScience/28_3.png,MAC_Bench/Cell/Cover/iScience/28_3.png,clip,28_3.txt,MAC_Bench/Cell/Cover/iScience/27_9.png,MAC_Bench/Cell/Cover/iScience/27_9.png,groundtruth,27_9.txt,train
Trends in Immunology,45_14,Which of the following options best describe the cover story?,"The image is an illustration of Louis Pasteur in his laboratory. A few
articles in this issue address vaccinology and the importance of better understanding
host immune responses to design better preventive or therapeutic vaccines. For
instance, Ellebedy and Wu discuss the potential of targeting neuraminidase to
generate broadly protective influenza virus vaccines; Guo and colleagues review
current information on mRNA vaccines in cancer nanomedicine and immunotherapy;
also, Levy, Palma et al. delve into the realm of modeling human immune responses to
vaccination in vitro. Image credit: GettyImages.",C,MAC_Bench/Cell/Cover/Trends in Immunology/44_7.png,MAC_Bench/Cell/Cover/Trends in Immunology/44_7.png,clip,44_7.txt,MAC_Bench/Cell/Cover/Trends in Immunology/44_6.png,MAC_Bench/Cell/Cover/Trends in Immunology/44_6.png,ave_2,44_6.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_14.png,groundtruth,45_14.txt,MAC_Bench/Cell/Cover/Trends in Immunology/46_1.png,MAC_Bench/Cell/Cover/Trends in Immunology/46_1.png,ave_3,46_1.txt,train
ACS Polymers Au,2024_3,Which of the following options best describe the cover story?,"Schematic representation of large size polar aggregates formed via hydrogen bonding between phosphate-terminated cis-1,4-polyisoprene chains in natural rubber (NR). The presence of multiple large size phosphate aggregates suggests a potential mechanism contributing to the superior comprehensive properties such as strain-induced crystallization observed in NR compared to synthetic polyisoprene.",D,MAC_Bench/ACS/Cover/ACS Polymers Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,ave_2,2023_6.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,vitg,2023_4.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_3.png,groundtruth,2024_3.txt,test
NATURE REVIEWS CANCER,25_2,Which of the following options best describe the cover story?,"Transitioning through mountain terrain, inspired by the Review on p7.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_3.png,ave_3,13_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_1.png,ave_2,25_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,clip,23_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,groundtruth,25_2.txt,test
ACS Applied Materials & Interfaces,2025_4,Which of the following options best describe the cover story?,"One novel nanoplatform integrating fluorescence/photothermal/magnetic resonance multimodal imaging with chemodynamic/photothermal/gas synergistic therapy has been successfully prepared, which exhibits an excellent colon cancer targeting and inhibiting effect.",B,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_32.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_32.png,vitg,2016_32.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_4.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_42.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_42.png,ave_2,2016_42.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_41.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_41.png,clip,2016_41.txt,val
Cell Genomics,4_8,Which of the following options best describe the cover story?,"On the cover: As we age—particularly with Alzheimer’s—various processes centered on
our DNA become gradually “broken.” Collectively, these changes, reviewed by Gouveia Roque et al. in this issue of Cell Genomics, act as drivers of disease progression and cognitive decline. The cover highlights
this relationship, drawing inspiration from the genetic mosaicism now known to characterize
the Alzheimer’s brain. Image credit: Cláudio Gouveia Roque.",A,MAC_Bench/Cell/Cover/Cell Genomics/4_8.png,MAC_Bench/Cell/Cover/Cell Genomics/4_8.png,groundtruth,4_8.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,clip,3_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,vitg,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_1.png,MAC_Bench/Cell/Cover/Cell Genomics/2_1.png,ave_1,2_1.txt,train
Accounts of Chemical Research,2025_2,Which of the following options best describe the cover story?,Elements of this cover art were generated with Adobe Firefly generative AI and blended with Adobe Photoshop.,A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_15.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_15.png,vith,2022_15.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_11.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_11.png,vitg,2024_11.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_9.png,clip,2024_9.txt,val
ACS Infectious Diseases,2024_2,Which of the following options best describe the cover story?,HBV persistence in the host cells is mediated by several regulatory proteins. E3 ubiquitin ligase UBR7 plays a crucial role in suppressing the IFN-β signaling and promotes viral proliferation leading to HBV-induced HCC.,C,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2015_10.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2015_10.png,clip,2015_10.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_6.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_6.png,ave_0,2018_6.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_2.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png,vitg,2024_10.txt,train
Industrial & Engineering Chemistry Research,2024_48,Which of the following options best describe the cover story?,"The hydroisomerization of n-heptane on Pt/WO3/ZrO2 catalyst takes place on Lewis and Brönsted acid sites, which synergistically convert the intermediate carbocations into branched C7-paraffins, thus contributing to the production of high-octane gasoline. Single-event kinetic modeling of the isomerization and cracking reactions has been used to elucidate the reaction mechanism.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_44.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_44.png,vitg,2022_44.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_48.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_48.png,groundtruth,2024_48.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_9.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_9.png,clip,2023_9.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_19.png,vith,2022_19.txt,train
ACS ES&T Engineering,2024_6,Which of the following options best describe the cover story?,"Laser-induced graphene-based electroconductive membranes (ECMs) have the potential for electro-cleaning of the fouled membranes. Non-oxidative electro-cleaning effectively prolongs the ECM lifespan by avoiding damage, while catalytic oxidative cleaning offers superior flux recovery for severely fouled membranes, highlighting innovative strategies for enhancing ECM performance in membrane technology.",A,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_6.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_1.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_1.png,vitg,2024_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_3.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_3.png,vith,2022_3.txt,train
Analytical Chemistry,2025_4,Which of the following options best describe the cover story?,"–ion mobility spectrometry (GC-IMS) as a point-of-need alternative for volatilomics. Furthermore, the capabilities and versatility of machine learning (chemometric) techniques used in the framework of GC-IMS analysis are also discussed. Art by the team of INMYWORK Studio.",C,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_23.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_23.png,clip,2020_23.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,vith,2022_33.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_4.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_10.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_10.png,vitg,2019_10.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_7,Which of the following options best describe the cover story?,"‘Iron-dependent cell death’, inspired by the Review on p424
Cover design: Vicky Summersby",C,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_4.png,clip,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_10.png,vith,23_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_7.png,groundtruth,25_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_6.png,vitg,15_6.txt,train
Nature Reviews Materials,9_10,Which of the following options best describe the cover story?,"Microscale robots' unique active motion enables their precise navigation in different aqueous biological or environmental media. The image shows an artist’s impression of microrobots using photocatalysis to degrade chemical and biological warfare agents for environmental remediation. See Chen C. et al
Cover image: David Johnston.",A,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_10.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_10.png,groundtruth,9_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_6.png,clip,7_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,vitg,9_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_2.png,ave_2,5_2.txt,train
Journal of Medicinal Chemistry,2024_2,Which of the following options best describe the cover story?,"This cover depicts a promising approach in drug discovery for the treatment of Alzheimer’s disease. Via phenotypic discovery of triple-target combinations with synergistic effects on microglia, an in silico restricted fragment docking strategy was developed to achieve “three birds with one stone”. The optimal ligand showed in vitro and in vivo efficacy by precisely modulating targets of interest. View the article.",D,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_14.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_14.png,ave_2,2020_14.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2012_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2012_4.png,clip,2012_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_11.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_11.png,ave_1,2021_11.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_2.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_2.png,groundtruth,2024_2.txt,test
Nature Plants,10_1,Which of the following options best describe the cover story?,"Rewiring for life on land
To colonize the land, plants had to evolve ways to obtain nutrients from barren terrains. The nutrient-response networks of liverworts, such as Marchantia polymorpha, show how this was achieved through extensive reorganization of the core components they share with distantly related, water-living algae
See Dong, Y. et al.
Image: Daisuke Urano, Temasek Life Sciences Laboratory. Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/Nature Plants/7_7.png,MAC_Bench/Nature/Cover/Nature Plants/7_7.png,clip,7_7.txt,MAC_Bench/Nature/Cover/Nature Plants/10_1.png,MAC_Bench/Nature/Cover/Nature Plants/10_1.png,groundtruth,10_1.txt,MAC_Bench/Nature/Cover/Nature Plants/9_1.png,MAC_Bench/Nature/Cover/Nature Plants/9_1.png,ave_2,9_1.txt,MAC_Bench/Nature/Cover/Nature Plants/4_6.png,MAC_Bench/Nature/Cover/Nature Plants/4_6.png,ave_3,4_6.txt,train
One Earth,7_2,Which of the following options best describe the cover story?,"On the cover: The Brazilian Amazon Açaí berry, which contains antioxidant, hypolipidemic,
and anti-inflammatory properties, has boosted local economies within the Brazilian
Amazon. This image captures baskets filled with Açaí placed at Feira do Açaí (Açaí
Market), a public trading open-air market specifically for Açaí, on the Ver-o-Peso
in Belé, the capital of Pará state in the Amazon region in the north of Brazil. Getty,
Paulo Amorim.",A,MAC_Bench/Cell/Cover/One Earth/7_2.png,MAC_Bench/Cell/Cover/One Earth/7_2.png,groundtruth,7_2.txt,MAC_Bench/Cell/Cover/One Earth/6_8.png,MAC_Bench/Cell/Cover/One Earth/6_8.png,vitg,6_8.txt,MAC_Bench/Cell/Cover/One Earth/5_8.png,MAC_Bench/Cell/Cover/One Earth/5_8.png,clip,5_8.txt,MAC_Bench/Cell/Cover/One Earth/7_3.png,MAC_Bench/Cell/Cover/One Earth/7_3.png,ave_3,7_3.txt,train
Nature Ecology & Evolution,8_7,Which of the following options best describe the cover story?,"Urban mutations
Ring-billed Gull in Hamilton Harbour, Hamilton, Canada, with steel-plant smokestacks in the background. The smokestacks emit polycyclic hydrocarbons that have been shown to induce heritable mutations in herring gulls and mammals. A Perspective by Johnson et al. highlights how such mutations may be important for the ecology, evolution and health of diverse organisms.
See Johnson et al.
Image: Marc Johnson. Cover Design: Allen Beattie.",A,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_7.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_7.png,groundtruth,8_7.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_7.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_7.png,vith,2_7.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_9.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_9.png,clip,8_9.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/1_3.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/1_3.png,vitg,1_3.txt,test
Current Biology,34_17,Which of the following options best describe the cover story?,"On the cover: Corynactis californica is a corallimorph—which are the closest living relatives of stony corals—that lives
in the cold waters of the Northeast Pacific. In this issue, Trznadel et al. show that Corynactis and many other anthozoans from this cold environment harbor
corallicolids, apicomplexan parasites that commonly infect corals and were previously
thought to be restricted to tropical coral reef ecosystems. Image by Patrick Keeling.",D,MAC_Bench/Cell/Cover/Current Biology/27_17.png,MAC_Bench/Cell/Cover/Current Biology/27_17.png,ave_3,27_17.txt,MAC_Bench/Cell/Cover/Current Biology/23_11.png,MAC_Bench/Cell/Cover/Current Biology/23_11.png,clip,23_11.txt,MAC_Bench/Cell/Cover/Current Biology/23_7.png,MAC_Bench/Cell/Cover/Current Biology/23_7.png,ave_2,23_7.txt,MAC_Bench/Cell/Cover/Current Biology/34_17.png,MAC_Bench/Cell/Cover/Current Biology/34_17.png,groundtruth,34_17.txt,train
Trends in Biotechnology,42_4,Which of the following options best describe the cover story?,"Even though cultivated meat has been approved for sale and consumption
in multiple countries, its consumer appeal remains low, in part because of poor perceptions
of palatability. In pages 1112–1127 of this issue, Lambert and colleagues discuss
scientific
and engineering approaches to improving palatability in cultivated meat. The cover
image
was inspired by the bright watercolor qualities of vintage food advertisements, displaying
the delicious appeal and palatability of this cell/ham hybrid which any housewife
would want
to serve on her table. Cover image from Marissa Sirois, VI4 Artist-in-Residence Program.",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_4.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_4.png,groundtruth,42_4.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_9.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_9.png,clip,38_9.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/40_10.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/40_10.png,vitg,40_10.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/41_6.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/41_6.png,vith,41_6.txt,train
Cell Stem Cell,32_1,Which of the following options best describe the cover story?,"On the cover: In this issue, Voit et al. report on the development of a unified gene therapy approach applicable to all patients
with the inherited bone marrow failure syndrome Diamond-Blackfan anemia (DBA). Mutations
in one of more than 30 genes cause erythroid maturation arrest in DBA, but regulated
lentiviral expression of the transcription factor GATA1 exclusively in developing
erythroid progenitors overcomes the erythroid maturation arrest irrespective of causative
gene mutation and improves erythroid output in DBA. The cover image depicts a blood
factory, representative of the bone marrow, with hematopoietic stem cells undergoing
differentiation. Some developing cells commit to erythroid differentiation but are
blocked by a pile of rubble with diamonds and black fans, representing DBA. To overcome
this, factory workers labeled GATA1 are running to help carry the progenitors around
the obstacle, leading to increased production of mature red blood cells. Cover illustrated
by DrawImpacts.",A,MAC_Bench/Cell/Cover/Cell Stem Cell/32_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/32_1.png,groundtruth,32_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/23_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/23_2.png,clip,23_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/6_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_1.png,vitg,6_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/9_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/9_1.png,vith,9_1.txt,test
Nature Structural & Molecular Biology,31_6,Which of the following options best describe the cover story?,"The scoop on γTuRC
Studies by Aher et al. and Dendooven et al. reveal the structure of the γ-tubulin ring complex (γTuRC) and show that it acts as a perfect template for 13-protofilament microtubules during nucleation.
See Aher et al. and Dendooven et al.
Image credit: Olivia Grigorita/500px/Getty images. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_6.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_6.png,groundtruth,31_6.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_1.png,vith,26_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_3.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_3.png,clip,30_3.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,vitg,28_8.txt,test
Cell Genomics,5_1,Which of the following options best describe the cover story?,"On the cover: The cover illustrates the dynamic process of bacterial immune adaptation
against bacterial viruses (phages) in different environments via a key mechanism of
acquiring CRISPR-Cas spacers, a study conducted by An-Ni Zhang et al. in this issue of Cell Genomics. The green section shows the rapid immunity update observed in controlled experimental
conditions, occurring on a timescale of hours. In contrast, the red section demonstrates
a much slower rate of CRISPR-Cas spacer acquisition in natural environments, such
as the human gut microbiome, where updates occur over several years. The findings
of this study further unravel the underlying mechanisms driving the continual arms
race between hosts and parasites in various organisms. Artist credit: An-Ni Zhang.",B,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,ave_2,4_12.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_1.png,MAC_Bench/Cell/Cover/Cell Genomics/5_1.png,groundtruth,5_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,clip,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,ave_3,4_7.txt,train
Structure,32_4,Which of the following options best describe the cover story?,"On the cover: Acid-switched antibodies with fully natural human domains can be developed
using light-chain shuffling and phage display technology. In Tulika et al., monoclonal antibodies with such pH-dependent antigen-binding properties were discovered
against snake venom toxins, which they bind at a neutral pH and release at a low pH.
Image credits: Esperanza Rivera de Torre, Monica Lisa Ines Fernandez Quintero, and
Andreas Hougaard Laustsen.",C,MAC_Bench/Cell/Cover/Structure/24_10.png,MAC_Bench/Cell/Cover/Structure/24_10.png,vith,24_10.txt,MAC_Bench/Cell/Cover/Structure/33_2.png,MAC_Bench/Cell/Cover/Structure/33_2.png,clip,33_2.txt,MAC_Bench/Cell/Cover/Structure/32_4.png,MAC_Bench/Cell/Cover/Structure/32_4.png,groundtruth,32_4.txt,MAC_Bench/Cell/Cover/Structure/24_6.png,MAC_Bench/Cell/Cover/Structure/24_6.png,vitg,24_6.txt,train
Nature Microbiology,9_11,Which of the following options best describe the cover story?,"Visualizing Tc toxin release
This image shows type 10 secretion system (T10SS)-mediated Tc toxin release by Yersinia entomophaga, as captured by cryo-electron tomography. Spanin-mediated membrane fusion triggers bacterial lysis and the explosive discharge of pre-assembled toxins by a subset of the bacterial population.
See Sitsel et al.
Credit: Oleg Sitsel and Stefan Raunser, Max Planck Institute of Molecular Physiology. Cover design: Valentina Monaco",D,MAC_Bench/Nature/Cover/Nature Microbiology/2_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/2_2.png,vith,2_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/7_1.png,MAC_Bench/Nature/Cover/Nature Microbiology/7_1.png,clip,7_1.txt,MAC_Bench/Nature/Cover/Nature Microbiology/3_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/3_2.png,vitg,3_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_11.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_11.png,groundtruth,9_11.txt,train
Biomacromolecules,2025_2,Which of the following options best describe the cover story?,"The cover prominently features a diatom and silicic acid molecule surrounded by macromolecules that represent the organic matrix or the “privileged space” where biosilicification occurs. Macromolecular chemistry guides the formation of their hierarchically structured silica biominerals. This Review of biosilicification literature explores in vivo and in vitro silicification studies and shows there is much to learn about the fundamental processes that control biosilicification. Moving forward, we can use biopolymer chemistry for hypothesis-directed studies to establish biosilicification principles.",B,MAC_Bench/ACS/Cover/Biomacromolecules/2024_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_10.png,clip,2024_10.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2025_2.png,MAC_Bench/ACS/Cover/Biomacromolecules/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2019_7.png,MAC_Bench/ACS/Cover/Biomacromolecules/2019_7.png,vith,2019_7.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_8.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_8.png,vitg,2021_8.txt,train
Cancer Cell,42_12,Which of the following options best describe the cover story?,"On the cover: Routy et al. review the microbiota research in the context of melanoma. The cover image demonstrates
the interplay between melanoma cancer cells and microbiota visually. An intricate
network of lines creates connections that symbolize the link between intestinal bacteria
and melanoma, highlighting the recent research included in the content, visually showcasing
the intricate relationship between the two. Image credit: Simon Rohlen, known as KEF!.",C,MAC_Bench/Cell/Cover/Cancer Cell/23_5.png,MAC_Bench/Cell/Cover/Cancer Cell/23_5.png,vitg,23_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/21_3.png,MAC_Bench/Cell/Cover/Cancer Cell/21_3.png,clip,21_3.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_12.png,MAC_Bench/Cell/Cover/Cancer Cell/42_12.png,groundtruth,42_12.txt,MAC_Bench/Cell/Cover/Cancer Cell/30_5.png,MAC_Bench/Cell/Cover/Cancer Cell/30_5.png,ave_1,30_5.txt,train
Nature Water,2_10,Which of the following options best describe the cover story?,"Linking water and ecosystems
Ecohydrology utilizes the knowledge of both ecological and hydrological processes across various scales. It focuses on the complex interactions between water and ecosystems: how water affects the ecological systems and how ecosystems, in turn, influence the water cycle and water quality. Research in ecohydrology aims to advance the understanding of the interactions and to provide solutions that contribute to enhancing ecosystem conservation and sustainable water resource management.
The cover shows a UNESCO Ecohydrology Demonstration Site: the area of Lake Wood, part of the Eddleston Water Project near Peebles, UK. The Eddleston Water Project serves as a dynamic testing ground for natural flood management techniques, which aim to bolster food resilience through the restoration of natural processes that slow water flow and increase water retention within the river system. This project demonstrates how ecohydrology research supports flood risk management, climate change adaptation and biodiversity enhancement at catchment scale.
See Editorial.
Image: Colin McLean Photography. Cover design: Valentina Monaco",B,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,vith,2_1.txt,MAC_Bench/Nature/Cover/Nature Water/2_10.png,MAC_Bench/Nature/Cover/Nature Water/2_10.png,groundtruth,2_10.txt,MAC_Bench/Nature/Cover/Nature Water/2_11.png,MAC_Bench/Nature/Cover/Nature Water/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Water/3_1.png,MAC_Bench/Nature/Cover/Nature Water/3_1.png,vitg,3_1.txt,test
ACS ES&T Air,2024_3,Which of the following options best describe the cover story?,"This study illustrates the molecular composition of organic aerosols collected in the Houston, Texas region using direct sampling interfaced with high-resolution mass spectrometry. This study highlights the episodic prevalence and day/nighttime distribution of organosulfates and organonitrates enriched species.",D,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,vitg,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,vith,2024_9.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,groundtruth,2024_3.txt,train
Cell Host&Microbe,33_1,Which of the following options best describe the cover story?,"On the cover: This illustration by Jiang et al. metaphorically represents the gut and brain as intricate mazes connected by the vagus
nerve. The NTS (nucleus tractus solitarius) acts as a signal controller, illustrated
as a traffic control center that manages neural signals at the CeA (central amygdala).
Roseburia intestinalis, portrayed as diligent workers in the lush, maze-like forest, produce butyrate, symbolized
by the yellow “fuel”. This butyrate powers the NTS and allows it to signal “red lights”
(inhibitory output) at the CeA, effectively blocking pro-nociceptive signals (the
“cars”) from traveling along the ascending pain pathway from the spinal cord. This
study reveals a mechanism of pain regulation via the gut-brain axis and underscores
the significant influence of microbiota-derived metabolites on pain-related neural
circuitry. This cover image was created by Beatrix Yu, a medical illustrator at CUHK.",B,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_2.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_2.png,clip,33_2.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_1.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_1.png,groundtruth,33_1.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,ave_3,27_5.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/23_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/23_3.png,vitg,23_3.txt,train
Bioconjugate Chemistry,2024_6,Which of the following options best describe the cover story?,"A norbornene-containing analogue of farnesyl diphosphate increases the utility of prenyltransferase-catalyzed protein labeling. In one application, a unique subset of prenylated proteins was observed via proteomics. In another",B,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_2.png,ave_1,2012_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_6.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_5.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_5.png,clip,2013_5.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_6.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_6.png,ave_2,2016_6.txt,train
ACS Applied Bio Materials,2024_11,Which of the following options best describe the cover story?,Daima and co-workers discuss engineered nanomaterials,C,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_1.png,vitg,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_3.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_3.png,clip,2019_3.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_11.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_6.png,vith,2024_6.txt,train
ACS Chemical Biology,2024_11,Which of the following options best describe the cover story?,"The toxicity of a nanopore-forming protein is controlled exclusively using visible light as a result of the incorporation of a water-soluble tetra-ortho-fluoro-substituted azobenzene photoswitch. The geometry of the switch under blue light prevents nanopore formation, while upon green light irradiation, the protein is activated, resulting in targeted cell destruction.",D,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_8.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_8.png,vith,2015_8.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_2.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_2.png,clip,2015_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2017_11.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2017_11.png,vitg,2017_11.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_11.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_11.png,groundtruth,2024_11.txt,train
Crystal Growth & Design,2024_11,Which of the following options best describe the cover story?,"The convolution of spatial confinement and interparticle interactions controls the formation of superparticles differing in structure and function, resulting in emergent properties. In this review, Marino et al. discuss recent developments in this topical area spanning length scales of colloidal particle assembly from nano- to micrometers. The cover image was AI-generated using Microsoft Copilot.",C,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_2.png,vith,2022_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_15.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_15.png,vitg,2024_15.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_11.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,clip,2017_5.txt,test
Nature Nanotechnology,19_4,Which of the following options best describe the cover story?,"Polariton condensation on the edge
The image presents a topologically protected polariton emission formed by hybridizing optical and excitonic excitations in a halide perovskite microcavity.
See Kai Peng et al.
Image: Kai Peng, Wei Li, and Wei Bao, Rensselaer Polytechnic Institute. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_4.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_4.png,groundtruth,19_4.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_5.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_5.png,vitg,19_5.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_8.png,vith,18_8.txt,val
Nature Mental Health,2_1,Which of the following options best describe the cover story?,"Epigenetic signatures of childhood adversity — risk and resilience
Childhood adversity, or the range of negative events that children can experience, encompasses all forms of physical and emotional abuse, neglect, and circumstances such as parental loss and poverty. Childhood adversity is associated with increased physical and mental health conditions, such as cardiovascular disease, alcohol and substance use, and depression. Epigenetic analyses can identify potential biomarkers of childhood adversity, such as DNA methylation that can change gene expression. Our cover depicts children on a playground, but one made of DNA. We chose to focus on one potential indication of methylation, as a biomarker that in some instances indicates reduced risk or resilience.
Read more about the consequences of childhood adversity in our Editorial and see the Article by Lussier et al. to read about epigenetic signatures that mediate the relationship between childhood adversity and depression.
Image: Marina Spence and Hibrida13 / iStock / Getty Images Plus. Cover design: Marina Spence",A,MAC_Bench/Nature/Cover/Nature Mental Health/2_1.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_1.png,groundtruth,2_1.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,ave_2,2_6.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,vitg,2_10.txt,train
Trends in Biochemical Sciences,49_5,Which of the following options best describe the cover story?,"For Gram-negative bacteria to survive and possess virulence, outer
membrane proteins (OMPs) must be properly made and maintained. In their article on
pages 667–680, Taylor Devlin and Dr. Karen Fleming describe the team of chaperones
and proteases with both redundant and unique functions that exist to help unfolded
precursor OMPs traverse the periplasm and facilitate proper OMP assembly at the OM.
Cover art by Anneliese Faustino.",B,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/42_8.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/42_8.png,vith,42_8.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_5.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_5.png,groundtruth,49_5.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_5.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_5.png,clip,45_5.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_7.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_7.png,ave_1,46_7.txt,val
ACS Sensors,2024_3,Which of the following options best describe the cover story?,"Ripe pears can undergo alcoholic fermentation. They release ethanol. Our system, based on enzymatic reactions, can image the distribution of ethanol released from pears. In other words, it is a conversion of odor information into visual information. It is expected that intelligent olfactory sensor systems will be used in agriculture, for example, to locate and sort ripe fruit based on odor-visual information.",B,MAC_Bench/ACS/Cover/ACS Sensors/2024_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_4.png,ave_3,2024_4.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_3.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Sensors/2018_12.png,MAC_Bench/ACS/Cover/ACS Sensors/2018_12.png,clip,2018_12.txt,MAC_Bench/ACS/Cover/ACS Sensors/2016_3.png,MAC_Bench/ACS/Cover/ACS Sensors/2016_3.png,vith,2016_3.txt,train
Environment & Health,2024_9,Which of the following options best describe the cover story?,"Toxicological assessment of compounds to aquatic life plays an important role in protecting the water environment from their hazards. We present a web-based server, AquaticTox, for predicting acute toxicity of organic compounds in aquatic organisms. This tool could facilitate the identification of aquatic toxic chemicals and the design of green molecules.",C,MAC_Bench/ACS/Cover/Environment & Health/2024_10.png,MAC_Bench/ACS/Cover/Environment & Health/2024_10.png,vith,2024_10.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,clip,2024_7.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Environment & Health/2023_3.png,MAC_Bench/ACS/Cover/Environment & Health/2023_3.png,vitg,2023_3.txt,train
Current Biology,34_11,Which of the following options best describe the cover story?,"On the cover: In this issue, Werner et al. demonstrate that contractile rings undergo speed oscillations that their experimental
and theoretical approaches suggest are due to periodic compaction and remodeling of
the actomyosin cytoskeleton. Here, gray shapes are cytokinetic ring positions in each
time point of timelapse image series for 20 control cells; the direction of furrowing
and the timing of bouts of acceleration and deceleration are random, but speed oscillations
and circumferential travel are consistent. Rainbow traces show speed (y axis) oscillations
of 72 5° segments around the ring of one control cell over time (x axis). Segments
at 3 o’clock (red) take turns being fastest with segments at 8 o’clock (green) and
finally at 10 o’clock (blue); all segments oscillate at a range of frequencies. Image
by Michael Werner and Amy Shaub Maddox.",A,MAC_Bench/Cell/Cover/Current Biology/34_11.png,MAC_Bench/Cell/Cover/Current Biology/34_11.png,groundtruth,34_11.txt,MAC_Bench/Cell/Cover/Current Biology/23_20.png,MAC_Bench/Cell/Cover/Current Biology/23_20.png,clip,23_20.txt,MAC_Bench/Cell/Cover/Current Biology/19_7.png,MAC_Bench/Cell/Cover/Current Biology/19_7.png,vith,19_7.txt,MAC_Bench/Cell/Cover/Current Biology/21_15.png,MAC_Bench/Cell/Cover/Current Biology/21_15.png,vitg,21_15.txt,val
iScience,27_3,Which of the following options best describe the cover story?,"The cover image is a digital artwork visualizing whale songs recorded by an ocean-bottom
seismometer array. Utilizing spectrum analysis and dynamic imaging techniques, Ren et al. created visuals based on the variation in the amplitudes of the seismic waveforms.
The higher amplitude indicates that the recorded noise was closer to the seismometer,
and the greater energy level of the whale song resulted in a more accurate silhouette
of the whale. The authors further integrated artistic methodologies to produce images
and videos from seismic waveforms recorded in the ocean, which enable the general
public to gain a multisensory experience of the ocean soundscape studied by specialists.
Their artwork provides new dimensions of scientific data representation, while its
creation is also driven by the analysis of scientific datasets.",A,MAC_Bench/Cell/Cover/iScience/27_3.png,MAC_Bench/Cell/Cover/iScience/27_3.png,groundtruth,27_3.txt,MAC_Bench/Cell/Cover/iScience/28_3.png,MAC_Bench/Cell/Cover/iScience/28_3.png,vitg,28_3.txt,MAC_Bench/Cell/Cover/iScience/26_10.png,MAC_Bench/Cell/Cover/iScience/26_10.png,vith,26_10.txt,MAC_Bench/Cell/Cover/iScience/14_1.png,MAC_Bench/Cell/Cover/iScience/14_1.png,clip,14_1.txt,val
Precision Chemistry,2024_2,Which of the following options best describe the cover story?,"The first Pd-catalyzed stereospecific C-glycosylation of reversed anomeric stannanes yields non-classical aryl and vinyl C-glycosides in good to excellent yields with exclusive stereocontrol, distinguishing this method as the current state-of-the-art.",A,MAC_Bench/ACS/Cover/Precision Chemistry/2024_2.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_9.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_9.png,ave_2,2023_9.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_11.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_11.png,ave_3,2024_11.txt,val
NATURE REVIEWS GENETICS,25_4,Which of the following options best describe the cover story?,"Inspired by the Review on p603.
Cover design: Patrick Morgan",C,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_4.png,groundtruth,25_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,clip,14_5.txt,train
Cell Reports Physical Science,5_6,Which of the following options best describe the cover story?,"On the cover: The cover, crafted by Guiyi Zhou, encapsulates the research of Xu et al. on leveraging advanced AI to transform polymeric gas separation membrane design.
It portrays a “polymer universe,” where dynamic interlocking yellow tracks represent
the complex polymer chains within an amorphous system. Shimmering stars scattered
throughout illustrate the gas molecules, emphasizing the focus on improving gas separation
efficiency. The spacecraft navigating this universe symbolizes the accelerating influence
of AI in propelling innovations in membrane technology.",A,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_6.png,groundtruth,5_6.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_10.png,ave_1,2_10.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_3.png,clip,1_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_2.png,ave_2,2_2.txt,test
Journal of Medicinal Chemistry,2024_18,Which of the following options best describe the cover story?,"The painting conveys an anti-depression theme using a small chemical molecule, S-3a, derived from the modification of the natural product scopolamine. Dark clouds symbolize depression, while S-3a pierces through them like an arrow, allowing the sun to shine on the Earth, symbolizing the treatment of depression.",D,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_16.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_16.png,clip,2021_16.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_14.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_14.png,vith,2022_14.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_4.png,ave_3,2020_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_18.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_18.png,groundtruth,2024_18.txt,train
Evidence-Based Dentistry,25_2,Which of the following options best describe the cover story?,"In this issue:
This issue covers an eclectic mix of evidence which highlights the enormous depth and diversity of knowledge and skill that it takes to be a practising dentist.
Cover illustration by Gary Neill",D,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_1.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_1.png,vitg,25_1.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,clip,24_4.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,vith,25_4.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_2.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_2.png,groundtruth,25_2.txt,val
The Journal of Physical Chemistry B,2025_5,Which of the following options best describe the cover story?,This work proposes a machine-learning-assisted solid-state nanopore for automated electrical sensing of vitamin B1 (thiamine) and its phosphorylated derivatives with high accuracy. The study introduces a novel strategy for rapid and precise micronutrient detection with a transverse quantum transport approach.,D,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_2.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_2.png,vitg,2022_2.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_21.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_21.png,vith,2023_21.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_5.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_5.png,clip,2021_5.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_5.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_5.png,groundtruth,2025_5.txt,val
Nature Structural & Molecular Biology,31_4,Which of the following options best describe the cover story?,"Remodeling membranes into phagophore-like cups
Using multiple imaging techniques, both in vitro and in vivo, Mohan, Moparthi et al. show that LCB3 works with the ATG121–ATG5–ATG16L1 complex to remodel flat membranes into membrane cups, providing insights into membrane remodeling processes needed for phagophore formation in non-selective autophagy.
See Mohan, Moparthi et al.
Image: Ann Manner / DigitalVision / Getty images. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_4.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_4.png,groundtruth,31_4.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/27_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/27_1.png,vitg,27_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_3.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_3.png,clip,30_3.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_7.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_7.png,vith,26_7.txt,val
Nature Photonics,18_4,Which of the following options best describe the cover story?,"Hyper-Raman optical activity
Hyper-Raman optical activity: circularly polarized infrared photons (red helices) incident on molecules arranged on a helical scaffold (white dots) produce hyper-Raman scattering spectra (multicoloured light regions) that feature chirality.
See Valev et al.
Image: Ventsislav K. Valev (University of Bath) and Kylian Valev (St Gregory's Catholic College Bath). Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Photonics/14_11.png,MAC_Bench/Nature/Cover/Nature Photonics/14_11.png,vitg,14_11.txt,MAC_Bench/Nature/Cover/Nature Photonics/16_6.png,MAC_Bench/Nature/Cover/Nature Photonics/16_6.png,vith,16_6.txt,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,clip,6_11.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,groundtruth,18_4.txt,train
ACS Sustainable Chemistry & Engineering,2025_7,Which of the following options best describe the cover story?,The CO2 tree highlights the breadth of chemical compounds currently accessible from CO2 to illustrate its potential to serve as a carbon source for the future.,A,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_7.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2017_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2017_10.png,ave_3,2017_10.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_12.png,vitg,2020_12.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2022_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2022_2.png,clip,2022_2.txt,test
Trends in Ecology & Evolution,39_2,Which of the following options best describe the cover story?,"Research on pollinator cognition usually focuses on a single reward
aspect in isolation. However, this does not reflect the complexity of reward types
that
pollinators encounter while foraging, as demonstrated by the Sonoran bumblebee,
Bombus sonorus collecting nectar, a complex mix of chemicals, from mealy sage
Salvia farinacea. On pages 1047–1058, Claire Hemingway and colleagues discuss
how reward complexity can impact pollinator cognition and demonstrate the need to
consider ecologically realistic rewards to fully understand plant–pollinator interactions.
Photo credit: Alexander Wild.",A,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_2.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_2.png,groundtruth,39_2.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/30_3.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/30_3.png,vitg,30_3.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_6.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_6.png,vith,36_6.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/24_6.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/24_6.png,clip,24_6.txt,train
Molecular Cell,85_3,Which of the following options best describe the cover story?,"On the cover: RNA modifications decorate RNA molecules, changing their physico-chemical
properties. Ribosomal RNAs (rRNAs) are heavily modified, with more than 200 modified
sites annotated in human rRNAs. In this issue of Molecular Cell, Milenkovic et al. systematically survey the rRNA modification patterns in development, differentiation,
and disease, finding that they represent epitranscriptomic fingerprints of their cells
and tissues of origin. These fingerprints can be used to predict developmental stages,
tissues, cell types, and cancer from as few as 250 reads. Cover artwork by Queralt
Tolosa (https://www.queralttolosa.com).",B,MAC_Bench/Cell/Cover/Molecular Cell/43_1.png,MAC_Bench/Cell/Cover/Molecular Cell/43_1.png,clip,43_1.txt,MAC_Bench/Cell/Cover/Molecular Cell/85_3.png,MAC_Bench/Cell/Cover/Molecular Cell/85_3.png,groundtruth,85_3.txt,MAC_Bench/Cell/Cover/Molecular Cell/54_4.png,MAC_Bench/Cell/Cover/Molecular Cell/54_4.png,vith,54_4.txt,MAC_Bench/Cell/Cover/Molecular Cell/51_2.png,MAC_Bench/Cell/Cover/Molecular Cell/51_2.png,vitg,51_2.txt,val
Crystal Growth & Design,2024_22,Which of the following options best describe the cover story?,"A three-step bending of a 7-acetoxy-4-methylcoumarin crystal upon UV light irradiation from one side of the crystal: First the crystal shows the action away from the light source, then toward the incident light, and finally again away from the light source. The motion is driven by the photodimerization and amorphization.",B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,clip,2019_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_22.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,vith,2018_1.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_5.png,vitg,2024_5.txt,test
Nature Neuroscience,27_2,Which of the following options best describe the cover story?,"Sculpting the brain during pregnancy
In this issue, Pritschet and colleagues offer a detailed map of a female human brain across gestation. Pronounced changes in gray and white matter demonstrate the brain’s capacity for extensive remodeling well into adulthood, paralleling the steep rise in hormone production. Reminiscent of sculpting marble, pregnancy is a transformative period of honing and refinement within the brain.
See Pritschet et al.
Image: Ella Maru Studio . Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Nature Neuroscience/9_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/9_11.png,clip,9_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/6_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/6_9.png,vith,6_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/8_8.png,MAC_Bench/Nature/Cover/Nature Neuroscience/8_8.png,vitg,8_8.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_2.png,groundtruth,27_2.txt,train
Trends in Parasitology,40_3,Which of the following options best describe the cover story?,"Parasitoid wasps are a highly diverse group of insects known for their
parasitic lifestyle. These species have become important models for multiple scientific
fields, including evolutionary biology and biological control. Advances in genomic
resources and research have greatly enhanced our understanding of parasitoid wasp
biology. In this issue of Trends in Parasitology, Ye and co-authors provide a comprehensive
overview of the current state of genome sequencing in parasitoid wasps, highlighting
how these genomic studies have led to significant breakthroughs in understanding the
evolution of parasitoid wasps and the genetic basis of key traits. Image credit: Xinhai
Ye.",B,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,vitg,34_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_3.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_3.png,groundtruth,40_3.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/35_13.png,MAC_Bench/Cell/Cover/Trends in Parasitology/35_13.png,clip,35_13.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/33_1.png,MAC_Bench/Cell/Cover/Trends in Parasitology/33_1.png,vith,33_1.txt,train
Med,5_5,Which of the following options best describe the cover story?,"On the cover: Xenotransplantation of engineered organs and tissues from different
species offers a promising solution to the major global challenge of finding suitable
donor organs for transplants. Results from early pig-to-human kidney xenotransplant
trials are encouraging, but the interactions between xenotransplanted organs and the
recipient require further characterization. In this issue of Med, Pan et al. apply single-cell sequencing to map the dynamics of xenograft-recipient interactions.
While they observe early signs of antibody-mediated rejection, the porcine kidney
shows evidence of rapid tissue repair after transplantation. These insights can be
used to design new engineered porcine models to optimize patient outcomes after xenotransplantation.",A,MAC_Bench/Cell/Cover/Med/5_5.png,MAC_Bench/Cell/Cover/Med/5_5.png,groundtruth,5_5.txt,MAC_Bench/Cell/Cover/Med/5_7.png,MAC_Bench/Cell/Cover/Med/5_7.png,vitg,5_7.txt,MAC_Bench/Cell/Cover/Med/4_1.png,MAC_Bench/Cell/Cover/Med/4_1.png,ave_1,4_1.txt,MAC_Bench/Cell/Cover/Med/2_7.png,MAC_Bench/Cell/Cover/Med/2_7.png,clip,2_7.txt,train
ACS Chemical Neuroscience,2024_8,Which of the following options best describe the cover story?,"Aberrant aggregation of amyloid-β peptides are considered the primary cause of Alzheimer’s disease. The caffeine-armed molecular tweezer demonstrates significant effectiveness in preventing the self-aggregation of these peptides and disrupting preformed amyloid fibrils through non-covalent interactions, especially π–π stacking with aromatic amino acid residues.",D,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2016_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2016_10.png,vith,2016_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,vitg,2020_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_8.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_8.png,groundtruth,2024_8.txt,train
BDJ In Practice,38_1,Which of the following options best describe the cover story?,"In this issue...
BDJ In Practice is 10! To celebrate, we assess how far the regulator and regulation has come in that time - for better or for worse",A,MAC_Bench/Nature/Cover/BDJ In Practice/38_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/38_1.png,groundtruth,38_1.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,vith,37_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/34_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/34_2.png,vitg,34_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,clip,36_1.txt,train
Nature Plants,10_5,Which of the following options best describe the cover story?,"Beating the bounds
Membranes host, modulate and coordinate a multitude of cellular activities. Different proteins are localized to different cell membranes, and domains within them, such as RECEPTOR-LIKE PROTEIN 4, which is found at cell edges and particularly at corners.
See Jaillais et al.
Image: Liam Elliot, ENS de Lyon. Cover design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Plants/10_5.png,MAC_Bench/Nature/Cover/Nature Plants/10_5.png,groundtruth,10_5.txt,MAC_Bench/Nature/Cover/Nature Plants/8_8.png,MAC_Bench/Nature/Cover/Nature Plants/8_8.png,ave_3,8_8.txt,MAC_Bench/Nature/Cover/Nature Plants/10_9.png,MAC_Bench/Nature/Cover/Nature Plants/10_9.png,vitg,10_9.txt,MAC_Bench/Nature/Cover/Nature Plants/4_9.png,MAC_Bench/Nature/Cover/Nature Plants/4_9.png,clip,4_9.txt,train
Nature Protocols,20_1,Which of the following options best describe the cover story?,"A bioswitchable delivery system for miRNA therapeutics
This image illustrates a bioswitchable delivery system designed to achieve controlled loading and release of miRNA regulators. A ribonuclease H-sensitive sequence functions as the bioswitchable apparatus, enabling release of the miRNA regulator upon ribonuclease H binding (green). See Li et al.
Image: Yunfeng Lin and Songhang Li, Sichuan University. Cover design: S. Harris.",C,MAC_Bench/Nature/Cover/Nature Protocols/15_3.png,MAC_Bench/Nature/Cover/Nature Protocols/15_3.png,vitg,15_3.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,vith,19_9.txt,MAC_Bench/Nature/Cover/Nature Protocols/20_1.png,MAC_Bench/Nature/Cover/Nature Protocols/20_1.png,groundtruth,20_1.txt,MAC_Bench/Nature/Cover/Nature Protocols/14_5.png,MAC_Bench/Nature/Cover/Nature Protocols/14_5.png,clip,14_5.txt,train
Cell Genomics,4_5,Which of the following options best describe the cover story?,"On the cover: One of the X chromosomes in females is inactivated through X chromosome
inactivation (XCI). However, several X-linked genes escape from XCI and contribute
to female-biased gene expression. In this issue of Cell Genomics, Tomofuji et al. develop scLinaX, a new bioinformatics tool to quantify the escape from XCI and elucidate
the sex differences of gene regulation. The cover art depicts leaky lights from the
inactivated X chromosome that represent the escape from XCI. Crafted by Anna Tsukasaki,
this image visually captures the essence of the scLinaX method.",D,MAC_Bench/Cell/Cover/Cell Genomics/3_9.png,MAC_Bench/Cell/Cover/Cell Genomics/3_9.png,vith,3_9.txt,MAC_Bench/Cell/Cover/Cell Genomics/1_3.png,MAC_Bench/Cell/Cover/Cell Genomics/1_3.png,clip,1_3.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_5.png,MAC_Bench/Cell/Cover/Cell Genomics/3_5.png,vitg,3_5.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_5.png,MAC_Bench/Cell/Cover/Cell Genomics/4_5.png,groundtruth,4_5.txt,train
Journal of Medicinal Chemistry,2024_4,Which of the following options best describe the cover story?,"1,2,4-Triazole-3-thione derivative HD2 is a highly potent and selective DCN1 inhibitor with favorable PK properties and low toxicity. Additionally, HD2 effectively relieved Ang II/TGFβ-induced cardiac fibroblast activation in vitro and reduced ISO-induced cardiac fibrosis as well as remodeling in vivo",B,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_9.png,vitg,2022_9.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_24.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_24.png,vith,2017_24.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,clip,2010_4.txt,train
Nature Cardiovascular Research,3_8,Which of the following options best describe the cover story?,"Macrophages improve the function of engineered cardiac microtissue
Hamidzada et al. show that after integration of human embryonic stem cell-derived macrophages into human cardiac microtissue, they adopt the resident fate and improve microtissue function by ingesting stressed cardiomyocytes or their cargo by efferocytosis.
See Hamidzada et al.
Image: Ella Maru Studio. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png,groundtruth,3_8.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_5.png,ave_3,3_5.txt,train
Nature Metabolism,6_3,Which of the following options best describe the cover story?,"Humans lacking GDF15
Humans lacking GDF15 have no overt phenotype, are fertile, and have healthy pregnancies. This finding has potential implications for the development of GDF15-targeting drugs, such as in the context of hyperemesis gravidarum or cachexia. The image depicts humans standing in the shape of a DNA molecule.
See Gurtan et al.
Image: Boris SV / Getty Images. Cover design: Thomas Phillips",A,MAC_Bench/Nature/Cover/Nature Metabolism/6_3.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_3.png,groundtruth,6_3.txt,MAC_Bench/Nature/Cover/Nature Metabolism/4_5.png,MAC_Bench/Nature/Cover/Nature Metabolism/4_5.png,vitg,4_5.txt,MAC_Bench/Nature/Cover/Nature Metabolism/2_5.png,MAC_Bench/Nature/Cover/Nature Metabolism/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_9.png,vith,6_9.txt,train
ACS Sustainable Resource Management,2024_11,Which of the following options best describe the cover story?,"The significance of AI in shaping a sustainable future is undeniable. Thus, ACS Sustainable Chemistry & Engineering and ACS Sustainable Resource Management encourage research articles and perspectives on the application of advanced technologies, which includes AI, for the development of sustainable chemical and engineering systems and resource management.",A,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_11.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,vith,2024_12.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,ave_1,2024_9.txt,train
Trends in Biotechnology,42_7,Which of the following options best describe the cover story?,"Interactions between algae and the phycosome may impact the productivity
of industrial cultures. This fluorescence microscopy image of an aggregate of Chlorella sp.
SLA-04 and its phycosome underlines the ecological complexity of xenic algal cultures.
In
pages 680-698 of this issue, Miller and colleagues highlight the current understanding
of
the phycosome and some future directions for taking advantage of phycosome ecology
in
production systems. Cover image taken by Isaac Miller at the Center for Biofilm Engineering
in the Imaging Core Facility.",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_7.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_7.png,groundtruth,42_7.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/29_2.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/29_2.png,ave_2,29_2.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/30_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/30_12.png,clip,30_12.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/32_1.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/32_1.png,vitg,32_1.txt,train
Science Signaling,2007_403,Which of the following options best describe the cover story?,"COVER This week features a Perspective on hedgehog signaling. The image shows cells close to and more distant from a source of the morphogen Sonic hedgehog. [Image: Christopher Bickel, AAAS]",C,MAC_Bench/Science/Cover/Science Signaling/2_60.png,MAC_Bench/Science/Cover/Science Signaling/2_60.png,vith,2_60.txt,MAC_Bench/Science/Cover/Science Signaling/12_578.png,MAC_Bench/Science/Cover/Science Signaling/12_578.png,clip,12_578.txt,MAC_Bench/Science/Cover/Science Signaling/2007_403.png,MAC_Bench/Science/Cover/Science Signaling/2007_403.png,groundtruth,2007_403.txt,MAC_Bench/Science/Cover/Science Signaling/6_258.png,MAC_Bench/Science/Cover/Science Signaling/6_258.png,vitg,6_258.txt,train
Nature Microbiology,9_1,Which of the following options best describe the cover story?,"Avian influenza in Antarctica
The International high pathogenicity avian influenza (HPAI) Australis Expedition 2024 monitored the spread of HPAI virus in Antarctica. A molecular diagnostic laboratory was set up on board the sailing boat Australis depicted in this image. Aguado et al. discuss the aims, challenges and learnings from this expedition, and how on-site diagnostics can be valuable for real-time surveillance of infectious disease outbreaks amongst wildlife.
See Aguado et al.
Image: Antonio Alcamí, Centro de Biología Molecular Severo Ochoa. Cover design: Laoise Mac Gabhann",A,MAC_Bench/Nature/Cover/Nature Microbiology/9_1.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Microbiology/7_6.png,MAC_Bench/Nature/Cover/Nature Microbiology/7_6.png,clip,7_6.txt,MAC_Bench/Nature/Cover/Nature Microbiology/7_11.png,MAC_Bench/Nature/Cover/Nature Microbiology/7_11.png,ave_3,7_11.txt,MAC_Bench/Nature/Cover/Nature Microbiology/8_7.png,MAC_Bench/Nature/Cover/Nature Microbiology/8_7.png,ave_2,8_7.txt,train
ACS Chemical Biology,2024_7,Which of the following options best describe the cover story?,"Measuring the cell penetration of biotherapeutics is challenging. New techniques are revealing precisely how much of a peptide or oligonucleotide drug penetrates to the cytosol or nucleus of target cells. Excitingly, these techniques are now being used to reveal differential penetration into different cell types, allowing drug developers to better understand how these drugs get into cells and what governs their cell-type selectivity. Cover art was generated with the assistance of Canva Magic Studio and Adobe Photoshop.",B,MAC_Bench/ACS/Cover/ACS Chemical Biology/2016_5.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2016_5.png,vitg,2016_5.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_7.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_4.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_4.png,ave_2,2015_4.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,clip,2019_9.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_5,Which of the following options best describe the cover story?,"A pharmacological concerto, inspired by the Perspective on p626.
Cover design: S. Harris",A,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_5.png,groundtruth,23_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,vitg,23_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_8.png,clip,22_8.txt,train
Science Signaling,2007_398,Which of the following options best describe the cover story?,"COVER This week's Focus Issue, published to complement the Science Special Issue on Challenges in Immunology, contains an Editorial Guide, a Review, and two Perspectives that discuss signals that affect the fate and responsiveness of T lymphocytes. The image depicts the activation of a naïve CD4+ T lymphocyte by a dendritic cell and its subsequent expansion and differentiation into a long-lived memory cell. [Image: Preston Huey, AAAS]",B,MAC_Bench/Science/Cover/Science Signaling/5_230.png,MAC_Bench/Science/Cover/Science Signaling/5_230.png,clip,5_230.txt,MAC_Bench/Science/Cover/Science Signaling/2007_398.png,MAC_Bench/Science/Cover/Science Signaling/2007_398.png,groundtruth,2007_398.txt,MAC_Bench/Science/Cover/Science Signaling/16_810.png,MAC_Bench/Science/Cover/Science Signaling/16_810.png,vitg,16_810.txt,MAC_Bench/Science/Cover/Science Signaling/8_366.png,MAC_Bench/Science/Cover/Science Signaling/8_366.png,vith,8_366.txt,train
Nature Cardiovascular Research,3_11,Which of the following options best describe the cover story?,"A bispecific antibody to treat bleeding disorders
Gandhi, Zivkovic, Østergaard et al. describe a bispecific antibody, HMB-001, that can be used for the potential prophylactic treatment of patients with genetic bleeding disorders.
See Ghandhi et al.
Image: Hemab ApS, Verge Scientific. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_1.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_9.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_9.png,vith,2_9.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_11.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_11.png,groundtruth,3_11.txt,train
Trends in Chemistry,6_6,Which of the following options best describe the cover story?,"Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for Part II continues on from Part I, highlighting some
of the
milestones and many paths taken on the 'great career race' for early-career scientists
today. Each running at their own pace, the authors in this special issue are all aiming
to innovate with an impact, solve real-world problems and become inspiring leaders
themselves. Artwork credit: Phillip Krzeminski",B,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,ave_2,6_8.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,groundtruth,6_6.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,vith,6_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,clip,6_7.txt,train
Nature Ecology & Evolution,8_11,Which of the following options best describe the cover story?,"Tasmanian predator interactions
The spotted-tailed quoll (Dasyurus maculatus, pictured) is a mesopredator that is subordinate to Tasmanian devils ((Sarcophilus harrisii). New genomic data show that quoll genetic structure has increased as devil populations have declined from a fatal, transmissible cancer. Top predators are declining globally, and this study shows that such declines can cause evolutionary responses in other predators, as well as ecological changes in food webs due to reduced competition.
See Beer et al
Image: Sebastian Comte. Cover Design: Allen Beattie.",B,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/7_3.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/7_3.png,vitg,7_3.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_11.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_11.png,groundtruth,8_11.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,clip,8_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_2.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_2.png,ave_3,5_2.txt,test
Nature Reviews Electrical Engineering,1_1,Which of the following options best describe the cover story?,"Photonic-crystal surface-emitting lasers is an emerging lasing technology that possess high brightness and high functionalities, while maintaining the merits of semiconductor lasers. The illustration depicts a train of pulsed laser beams emitted from the surface of a Photonic-crystal surface-emitting laser. See Noda.
Image: Susumu Noda, Kyoto University. Cover design: Sam Whitham.",B,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,groundtruth,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,ave_3,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_2.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_2.png,clip,1_2.txt,train
NATURE REVIEWS GENETICS,25_8,Which of the following options best describe the cover story?,"Inspired by the Review on p309
Cover design: Patrick Morgan",A,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_8.png,groundtruth,25_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/24_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/24_1.png,clip,24_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/19_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/19_11.png,vitg,19_11.txt,train
Nature Ecology & Evolution,9_1,Which of the following options best describe the cover story?,"Lemur evolution
Madagascar is home to an extraordinary level of endemic biodiversity, but quantifying this is complicated by cryptic diversity among some genera such as mouse lemurs (genus Microcebus). Van Elst et al. shed light on this by presenting a generalizable, integrative framework to characterize the species diversity of this taxonomically controversial genus, demonstrating that it has been overestimated. The photograph depicts Madame Berthe’s mouse lemur (Microcebus berthae), which may recently have gone extinct, in Menabe Central Forest in Madagascar. In a second paper in this issue, Orkin et al. analyse genome-wide resequencing data from 50 species of lemurs, revealing high levels of genomic diversity and demographic declines consistent with the historic timing of human expansion across the island.
See Tobias van Elst et al. and Joseph D. Orkin et al.
Image: Nick Garbutt. Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_6.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_6.png,ave_2,2_6.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/9_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/1_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,vitg,8_8.txt,train
ACS Infectious Diseases,2024_8,Which of the following options best describe the cover story?,"An efflux pump inhibitor, IITR08367, disrupts bacterial energetics that lead to reduced fosfomycin efflux and biofilm formation in Acinetobacter baumannii.",D,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_7.png,vith,2018_7.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2019_5.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2019_5.png,vitg,2019_5.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2017_2.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2017_2.png,clip,2017_2.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_8.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_8.png,groundtruth,2024_8.txt,train
The Journal of Physical Chemistry A,2025_3,Which of the following options best describe the cover story?,"Ab initio trajectory simulations of the reaction between chloramine (NH2Cl) and methoxide ion (CH3O-) reveal a dominant proton transfer and minor SN2 products, consistent with experimental findings. Additionally, novel hydride transfer and unconventional roundabout pathways are observed in the nitrogen-centered reaction.",A,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_3.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2023_32.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2023_32.png,ave_2,2023_32.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_19.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_19.png,vith,2024_19.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2021_33.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2021_33.png,clip,2021_33.txt,train
Chemical & Biomedical ImagingOpen Access,2024_11,Which of the following options best describe the cover story?,"The CBT-Cys click reaction and its derived reactions (i.e., CHQ-Cys and PMN-Cys) have made outstanding contributions to the design of smart bioimaging probes due to their good biocompatibility and self-assembly properties. In this review, we focus on the concept, mechanism, and research progress of CBT-Cys-like reactions.",C,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_8.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_6.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_6.png,ave_0,2023_6.txt,train
NATURE REVIEWS NEUROSCIENCE,25_8,Which of the following options best describe the cover story?,"‘The language network’, inspired by the Review on p289.
Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,vitg,25_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_10.png,clip,24_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/23_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/23_5.png,vith,23_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_8.png,groundtruth,25_8.txt,train
Nature Geoscience,17_9,Which of the following options best describe the cover story?,"Mud glorious mud
Human activities have altered the production, transport, and fate of mud and associated organic carbon, with important implications for global carbon cycling. The image shows a mudflat under the bridge to the island Oléron in Charente-Maritime, France.
See Bianchi et al.
Image: Amar and Isabelle Guillen—Guillen Photo LLC/Alamy Stock Photo. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/14_11.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_11.png,vitg,14_11.txt,MAC_Bench/Nature/Cover/Nature Geoscience/5_5.png,MAC_Bench/Nature/Cover/Nature Geoscience/5_5.png,vith,5_5.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_9.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_9.png,groundtruth,17_9.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_10.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_10.png,clip,17_10.txt,train
Nature Food,5_10,Which of the following options best describe the cover story?,"Nutrient retention in aquaculture
Salmon has one of the most efficient feed-to-food conversion rates among farmed animals, but its high trophic level makes salmon aquaculture a major consumer of marine resources — including species that are consumed directly by people, such as herring and mackerel. Re-allocating species currently used in salmon feeds towards direct human consumption can increase the overall amount of nutritious seafood while avoiding increases in wild-caught fish supply. Most edible feed fish contains higher concentrations of omega-3 fatty acids, iodine, calcium, iron and vitamin A than farmed salmon. Nutrient retention approaches can drive better performance of aquaculture and identify pathways towards sustainable growth.
See Willer et al.
Image: Jeff Rotman / Alamy Stock Photo. Cover Design: Tulsi Voralia.",D,MAC_Bench/Nature/Cover/Nature Food/5_6.png,MAC_Bench/Nature/Cover/Nature Food/5_6.png,ave_1,5_6.txt,MAC_Bench/Nature/Cover/Nature Food/1_1.png,MAC_Bench/Nature/Cover/Nature Food/1_1.png,ave_3,1_1.txt,MAC_Bench/Nature/Cover/Nature Food/3_5.png,MAC_Bench/Nature/Cover/Nature Food/3_5.png,clip,3_5.txt,MAC_Bench/Nature/Cover/Nature Food/5_10.png,MAC_Bench/Nature/Cover/Nature Food/5_10.png,groundtruth,5_10.txt,train
NATURE REVIEWS IMMUNOLOGY,24_6,Which of the following options best describe the cover story?,"Sex differences in Immunity, inspired by the Review on p487.
Cover design: Simon Bradbrook",C,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,vitg,18_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_6.png,groundtruth,24_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_6.png,ave_1,13_6.txt,val
Nature Aging,4_2,Which of the following options best describe the cover story?,"Nonlinear multi-omics aging
In this issue, Xiaotao Shen, Chuchu Wang and colleagues performed comprehensive multi-omics profiling in a cohort of 108 human participants and reveal nonlinear patterns in molecular markers of aging. The cover shows a heatmap depicting nonlinear changing data.
See Shen et al.
Image: Michael Snyder & Xiaotao Shen. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Aging/1_2.png,MAC_Bench/Nature/Cover/Nature Aging/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Aging/4_2.png,MAC_Bench/Nature/Cover/Nature Aging/4_2.png,groundtruth,4_2.txt,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,ave_2,4_11.txt,MAC_Bench/Nature/Cover/Nature Aging/2_6.png,MAC_Bench/Nature/Cover/Nature Aging/2_6.png,vith,2_6.txt,train
Journal of Medicinal Chemistry,2024_9,Which of the following options best describe the cover story?,This cover art illustrates how an optimization of stereochemistry (represented by the chiral molecules in the flasks) and electrostatics (represented by a Tesla coil in the glass container) in a glycomimetic ligand resulted in the formation of an enthalpically driven cooperative hydrogen-bond network with its target DC-SIGN. A generative AI tool (Adobe Firefly) was used to create a part of the artwork. The authors are grateful for the assistance of Dilara Tastan and Serdal Tastan in the creation of the cover art.,A,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_5.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_5.png,clip,2022_5.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_16.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_16.png,ave_1,2022_16.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_12.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_12.png,vitg,2018_12.txt,train
Nature Neuroscience,27_3,Which of the following options best describe the cover story?,"AI framework for neural–behavioral modeling
Neural dynamics are complex and simultaneously relate to distinct behaviors. To address these challenges, Sani et al. have developed an AI framework termed DPAD that achieves nonlinear dynamical modeling of neural–behavioral data, dissociates behaviorally relevant neural dynamics, and localizes the source of nonlinearity in the dynamical model. In the cover image, what DPAD does is visualized as separating the ovsubbed erall brain activity into distinct pieces related to specific behaviors and discovering how these pieces fit together to build the overall activity.
See Sani et al.
Image: Ella Maru Studio, Omid Sani, Maryam Shanechi. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/Nature Neuroscience/11_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/11_11.png,vitg,11_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_3.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_3.png,groundtruth,27_3.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/9_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/9_2.png,clip,9_2.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/21_8.png,MAC_Bench/Nature/Cover/Nature Neuroscience/21_8.png,vith,21_8.txt,train
Developmental Cell,59_1,Which of the following options best describe the cover story?,"On the cover: This is a confocal image of the suprachiasmatic nucleus (SCN), a primary
brain target of retinal ganglion cells (RGC) responsible for circadian rhythms, in
a 6-week-old mouse. The SCN is labeled by intravitreal injection of fluorescent dye-conjugated
cholera toxin B (CTB), which is taken up by RGC. The right eye received Alexa Fluor
647-conjugated CTB and the left eye received Alexa Fluor 555-conjugated CTB to allow
visualization of ipsi- and contralateral projections in each SCN. To learn more about
how regenerating RGC axons can be guided in the mature brain to functionally reconnect
the SCN, see Delpech et al. Image credit: Julia Schaeffer, Homaira Nawabi, and the Photonic Imaging Center of
Grenoble Institute Neuroscience.",C,MAC_Bench/Cell/Cover/Developmental Cell/20_2.png,MAC_Bench/Cell/Cover/Developmental Cell/20_2.png,vith,20_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/18_2.png,MAC_Bench/Cell/Cover/Developmental Cell/18_2.png,clip,18_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_1.png,MAC_Bench/Cell/Cover/Developmental Cell/59_1.png,groundtruth,59_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/58_24.png,MAC_Bench/Cell/Cover/Developmental Cell/58_24.png,vitg,58_24.txt,train
ACS ES&T Water,2025_1,Which of the following options best describe the cover story?,The front cover by postgraduate student Kemi Oloyede at Imperial College London is part of the Diversity and Inclusion Cover Art Series,A,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_7.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_7.png,ave_2,2021_7.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_3.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_3.png,ave_3,2021_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_6.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_6.png,clip,2024_6.txt,train
NATURE METHODS,21_4,Which of the following options best describe the cover story?,"Enhancing lamella preparation for cryo-ET with serial lift-out
Artistic representation of the sectioning step in a focused ion beam-based sample preparation technique, Serial Lift-Out. A block of vitreously frozen biological material (here, a C. elegans L1 larva embedded in buffer) is attached to a micromanipulator needle and transferred to a rectangular-mesh copper electron microscopy grid to be serially sectioned.
See Article
Image: Jürgen M. Plitzko. Cover design: Thomas Phillips",D,MAC_Bench/Nature/Cover/NATURE METHODS/12_7.png,MAC_Bench/Nature/Cover/NATURE METHODS/12_7.png,vitg,12_7.txt,MAC_Bench/Nature/Cover/NATURE METHODS/16_5.png,MAC_Bench/Nature/Cover/NATURE METHODS/16_5.png,clip,16_5.txt,MAC_Bench/Nature/Cover/NATURE METHODS/17_4.png,MAC_Bench/Nature/Cover/NATURE METHODS/17_4.png,vith,17_4.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_4.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_4.png,groundtruth,21_4.txt,train
Structure,32_12,Which of the following options best describe the cover story?,"On the cover: The cover figure depicts the complex structure of the bacteriophage
HRP29 virion. A novel tail adapter protein is utilized to create a hybrid tail that
has unique receptor binding properties. Subramanian et al. utilized cryo-electron microscopy to deduce how all of the structural proteins come
together to form this phage. They used a variety of biological assays such as temperature
sensitivity assays and CRISPR-Cas knockdowns to determine essential protein building
blocks that help stabilize this phage and are critical for infection. Image credit:
Júlio Arvellos.",D,MAC_Bench/Cell/Cover/Structure/32_5.png,MAC_Bench/Cell/Cover/Structure/32_5.png,vitg,32_5.txt,MAC_Bench/Cell/Cover/Structure/19_8.png,MAC_Bench/Cell/Cover/Structure/19_8.png,vith,19_8.txt,MAC_Bench/Cell/Cover/Structure/22_7.png,MAC_Bench/Cell/Cover/Structure/22_7.png,clip,22_7.txt,MAC_Bench/Cell/Cover/Structure/32_12.png,MAC_Bench/Cell/Cover/Structure/32_12.png,groundtruth,32_12.txt,train
Nature Reviews Rheumatology,20_9,Which of the following options best describe the cover story?,"Inspired by the Review on p241.
Cover design: Steven Hall",A,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_9.png,groundtruth,20_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,vitg,20_11.txt,train
Science,387_6733,Which of the following options best describe the cover story?,"COVER Cultural reverence toward tigers (Panthera tigris) has fostered tolerance and permitted coexistence with humans in India. Ecological restoration, socioeconomic policies, and political stability have facilitated the recovery of tigers within their historical range, despite high human densities. This tigress has reclaimed the ancient fort within Bandhavgarh Tiger Reserve and made it her home. See page 505.
Photo: Yashpal Rathore",B,MAC_Bench/Science/Cover/Science/353_6307.png,MAC_Bench/Science/Cover/Science/353_6307.png,ave_2,353_6307.txt,MAC_Bench/Science/Cover/Science/387_6733.png,MAC_Bench/Science/Cover/Science/387_6733.png,groundtruth,387_6733.txt,MAC_Bench/Science/Cover/Science/359_6374.png,MAC_Bench/Science/Cover/Science/359_6374.png,clip,359_6374.txt,MAC_Bench/Science/Cover/Science/325_5940.png,MAC_Bench/Science/Cover/Science/325_5940.png,vith,325_5940.txt,val
ACS Nanoscience Au,2024_2,Which of the following options best describe the cover story?,"Many metal nanoparticles adopt a face centered cubic (fcc) crystal structure, as shown on the cover. The surfaces of four facets of this fcc nanoparticle are highlighted on the nanoparticle. Enlarged regions of the atomic arrangements of the surfaces of these facets are shown, along with the subsurface atoms.",B,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_5.png,clip,2023_5.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_3.png,ave_3,2024_3.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_4.png,vitg,2022_4.txt,train
Chemical & Biomedical ImagingOpen Access,2024_2,Which of the following options best describe the cover story?,Correlating the subcellular location of essential metals and proteins in neurons using fluorescence light microscopy and synchrotron X-ray fluorescence imaging under cryogenic conditions to preserve native cell structure and bio-molecule distribution. Part of this cover was created using AI Copilot Designer.,B,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_2.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_4.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_4.png,ave_2,2023_4.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,vitg,2023_5.txt,train
Molecular Pharmaceutics,2024_4,Which of the following options best describe the cover story?,"The cover shows a novel therapeutic fusion protein that occurs as a homodimer. One monomer is colored according to the hydrogen exchange results, and the other monomer is colored according to the computational modeling results, both performed to understand the sites responsible for reversible self-association. The methodologies are indicated schematically, and the dual-colored dimer indicates the symbiosis of these methodologies.",A,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_6.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_6.png,clip,2020_6.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2025_2.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2025_2.png,vith,2025_2.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,vitg,2022_8.txt,train
Trends in Biochemical Sciences,50_1,Which of the following options best describe the cover story?,"Heat shock activates a gene expression program to prevent irreversible
damage to macromolecules. On pages 18–32 in this issue, Desroches Altamirano
and Alberti explore how heat shock affects the protein “building blocks’’ in a cell
and
how this promotes a stress response. Heat shock inactivates certain protein blocks,
connects them into larger structures with mRNA and represses general protein
synthesis. Simultaneously, other protein blocks facilitate the synthesis of first-aid
protein blocks (HSPs) to help restore protein blocks with “compromised” structure.
Illustrated by Dr. Desroches Altamirano.",D,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,ave_2,44_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/41_8.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/41_8.png,ave_3,41_8.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,clip,50_2.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_1.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_1.png,groundtruth,50_1.txt,val
ACS Chemical Neuroscience,2024_2,Which of the following options best describe the cover story?,"Amyloid fibrils can be generated from a large range of food proteins, which may directly contact disease-associated amyloidogenic proteins in certain scenarios, such as for medical applications or individuals with digestive disorders. In this study, we show the biological effects of food amyloid fibrils when exposed to a series of conventional cell lines.",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_2.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_3.png,clip,2017_3.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,vith,2023_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_5.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_5.png,ave_2,2021_5.txt,train
Nature Ecology & Evolution,8_2,Which of the following options best describe the cover story?,"Underwater alliances
Individuals of the day octopus (Octopus cyanea) sometimes team up with various fish species such as the blue goldsaddle goatfish (Parupeneus cyclostomus) to engage in collective hunting. Three-dimensional field-based tracking and field experiments unravel the complex social influences that drive decision-making, and reveal shared leadership across these distantly related species.
See Eduardo Sampaio et al.
Image: Eduardo Sampaio. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_6.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_6.png,vith,4_6.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_8.png,clip,5_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_2.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_2.png,groundtruth,8_2.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/6_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/6_1.png,vitg,6_1.txt,train
NATURE IMMUNOLOGY,25_6,Which of the following options best describe the cover story?,"Immune signatures of pain
Single-cell transcriptomics is used to determine the gene signature of infiltrating immune cells and potential cell–cell interactions between receptors, ligands, ion channels and metabolites expressed on immune cells and sensory neurons in three models of inflammatory pain.
See Jain et al.
Image: Sara Hakim, Boston Children’s Hospital. Cover design: Emily Paul",C,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,clip,11_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_5.png,vitg,22_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_6.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_6.png,groundtruth,25_6.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_10.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_10.png,vith,10_10.txt,test
Cell Reports Methods,4_9,Which of the following options best describe the cover story?,"On the cover: In this issue, Waas et al. develop an accessible, low-input proteomics platform called DROPPS. The cover image
is an artistic rendering of the proteomics platform where the disco balls, generated
from heatmaps, represent cellular heterogeneity. Image credit: Matthew Waas, PhD.",D,MAC_Bench/Cell/Cover/Cell Reports Methods/2_5.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_5.png,vith,2_5.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,clip,2_11.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_2.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_2.png,ave_2,3_2.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_9.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_9.png,groundtruth,4_9.txt,val
Science Robotics,9_94,Which of the following options best describe the cover story?,"ONLINE COVER Grasping Objects with Prosthetics. Amputation of a limb can affect the ability of an amputee to carry out simple tasks, such as grasping an object. Several prosthetic devices rely on the use of electrical signals from nerves and muscles to control their motion. Gherardini et al. have developed an approach that uses implanted magnets that harness muscle deformation to control a myokinetic prosthetic hand. A participant with a transradial amputation recruited for the study showed the ability to carry out functional tests to demonstrate dexterous motor skills. This month’s cover is an image of the participant’s prosthetic hand grasping a clothespin. Credit: OneFrame Creative Science Communication",D,MAC_Bench/Science/Cover/Science Robotics/8_83.png,MAC_Bench/Science/Cover/Science Robotics/8_83.png,clip,8_83.txt,MAC_Bench/Science/Cover/Science Robotics/7_72.png,MAC_Bench/Science/Cover/Science Robotics/7_72.png,ave_2,7_72.txt,MAC_Bench/Science/Cover/Science Robotics/7_67.png,MAC_Bench/Science/Cover/Science Robotics/7_67.png,vitg,7_67.txt,MAC_Bench/Science/Cover/Science Robotics/9_94.png,MAC_Bench/Science/Cover/Science Robotics/9_94.png,groundtruth,9_94.txt,test
Trends in Pharmacological Sciences,46_2,Which of the following options best describe the cover story?,"Recent studies have highlighted the complexity of platelet biology, revealing
their diverse roles beyond hemostasis. Pathological platelet activation is now recognized
as
a key contributor to thrombosis and inflammation, both of which are central to cardiovascular
disease (CVD). Emerging research emphasizes the considerable impact of demographic
factors—such as age, sex, race, and ethnicity—on CVD risk and responses to antiplatelet
therapies. In this issue, Jain, Tyagi and colleagues review the influence of genetic
and non-genetic
factors including age, sex, race, and ethnicity on platelet function and responses
to
antiplatelet therapies. They emphasize the pressing need for further research into
platelet
biology and cardiovascular outcomes across diverse populations and advocate for tailored
therapeutic approaches in CVD based on recent demographic findings. The cover image,
conceptualized and designed by Kanika Jain and Tarun Tyagi using BioRender, features
a
heart, representing cardiovascular health, and hands holding platelets and medications,
symbolizing the interplay between pathological platelet activation—associated with
thrombosis—and therapeutic strategies crucial for CVD management. The diverse
individuals illustrate the impact of demographic factors on CVD risk. Images of heart
and
hands are from Adobe Stock images.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_11.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_11.png,ave_3,40_11.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_3.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_3.png,vitg,42_3.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_2.png,groundtruth,46_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_1.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_1.png,clip,46_1.txt,train
Nature Neuroscience,27_1,Which of the following options best describe the cover story?,"Focus on single-cell genomics in neuroscience
Single-cell and single-nucleus genomics pave the way for a comprehensive understanding of the nervous system and its diverse cell populations. Realizing this potential depends on meticulous planning, execution, and analysis. In this Focus Issue, three reviews from leaders in the field summarize best practices. The cover illustration symbolizes this effort with two hands pulling on a string, unraveling the complexity of the nervous system.
See Gokce et al. , Nowakowski et al. and Liddelow et al.
Image: Tyas Widayati. Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Nature Neuroscience/14_8.png,MAC_Bench/Nature/Cover/Nature Neuroscience/14_8.png,vith,14_8.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/21_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/21_9.png,vitg,21_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_1.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_1.png,groundtruth,27_1.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/14_3.png,MAC_Bench/Nature/Cover/Nature Neuroscience/14_3.png,clip,14_3.txt,train
Industrial & Engineering Chemistry Research,2024_2,Which of the following options best describe the cover story?,"There have been many recent advancements in regulating microenvironments to enhance CO2 conversion, focusing on copper-based catalysts, featuring strategies like single-atom catalyst design, particle size/facets/morphology control, confinement effects, and interfacial engineering to optimize active site density, control reactant/intermediate concentrations, and promote charge transfer processes.",C,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_23.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_23.png,vith,2022_23.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_2.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_19.png,clip,2021_19.txt,train
Precision Chemistry,2024_10,Which of the following options best describe the cover story?,Thio ligand-modified Au nanoparticles as an extraordinary electrocatalyst enhanced the electroreduction of nitrate to ammonia due to the regulated electronic structure.,D,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_8.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_8.png,vitg,2023_8.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_7.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_7.png,ave_2,2023_7.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_10.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_10.png,groundtruth,2024_10.txt,train
ACS Applied Optical Materials,2024_9,Which of the following options best describe the cover story?,"A multishell nanoparticle comprised of an ultrabright perovskite core and a nitric oxide sensitive orange-fluorescent emitting dye facilitating real-time imaging and ratiometric biosensing, especially in deep tissue.",B,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,clip,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_1.png,ave_3,2023_1.txt,train
Current Biology,34_24,Which of the following options best describe the cover story?,"On the cover: Orchid mantis Hymenopus coronatus, distributed in the tropical areas of China and Southeast Asia, is famous for its
floral resemblance, which has been considered as an example of flower mimicry for
over 200 years. However, in this issue, Zhao et al. document its gliding performance and show that the petal-shaped femoral lobes are
crucial for gliding. Behavioral and morphological analyses suggest that gliding might
be the evolutionary motivation of these lobes. Image by Xin Zhao.",C,MAC_Bench/Cell/Cover/Current Biology/18_6.png,MAC_Bench/Cell/Cover/Current Biology/18_6.png,vith,18_6.txt,MAC_Bench/Cell/Cover/Current Biology/32_10.png,MAC_Bench/Cell/Cover/Current Biology/32_10.png,clip,32_10.txt,MAC_Bench/Cell/Cover/Current Biology/34_24.png,MAC_Bench/Cell/Cover/Current Biology/34_24.png,groundtruth,34_24.txt,MAC_Bench/Cell/Cover/Current Biology/30_22.png,MAC_Bench/Cell/Cover/Current Biology/30_22.png,vitg,30_22.txt,test
Industrial & Engineering Chemistry Research,2024_33,Which of the following options best describe the cover story?,The cover sketches the challenge of integrating multiple scales into a process model and how this can be performed with compartment models. These compartment models are applied to an industrial rotary dryer shown in the figures and the background.,B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_12.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_12.png,ave_2,2020_12.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_33.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_33.png,groundtruth,2024_33.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_51.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_51.png,ave_1,2024_51.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_4.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_4.png,clip,2020_4.txt,train
Science Advances,11_8,Which of the following options best describe the cover story?,"ONLINE COVER Artistic rendering of a universal prion-based mechanism for ionic strength sensing (represented by gauge) inside animal cells. An ever-expanding fraction of the global population faces rising temperatures and water scarcity, conditions that place excessive ionic stress on cells and tissues. Khandwala et al. show that increasing ionic strength inside cells activates a mitigative transcriptional program controlled by the protein NFAT5. This discovery links climate medicine and cell biology, providing a foundation for developing therapies against climate change-associated diseases, including chronic kidney disease. Credit: Kate Zvorykina and Ella Marushchenko (Ella Maru Studio, Inc.)",C,MAC_Bench/Science/Cover/Science Advances/9_14.png,MAC_Bench/Science/Cover/Science Advances/9_14.png,vitg,9_14.txt,MAC_Bench/Science/Cover/Science Advances/9_20.png,MAC_Bench/Science/Cover/Science Advances/9_20.png,clip,9_20.txt,MAC_Bench/Science/Cover/Science Advances/11_8.png,MAC_Bench/Science/Cover/Science Advances/11_8.png,groundtruth,11_8.txt,MAC_Bench/Science/Cover/Science Advances/9_23.png,MAC_Bench/Science/Cover/Science Advances/9_23.png,ave_1,9_23.txt,train
Cancer Cell,42_9,Which of the following options best describe the cover story?,"On the cover: In this issue of Cancer Cell, two papers by Barisic et al. and Deng et al. evaluate how mutations in components of the BAF complex lead to the development of
B cell malignancies. In the cover, Barisic et al. demonstrate that ARID1A is required
for continuous eviction of nucleosomes, facilitating the sequential binding of transcription
factors necessary for safeguarding germinal center B cell fate towards plasma cells.
The cover image symbolizes ARID1A as Sisyphus, exerting significant effort and energy
to push boulders uphill, analogous to the BAF complex and ARID1A using energy from
ATP hydrolysis for nucleosome eviction. Birds in the image symbolize the antibodies
produced by plasma cells when ARID1A effectively remodels nucleosomes. Credit: Art
by Inmywork Studio.",A,MAC_Bench/Cell/Cover/Cancer Cell/42_9.png,MAC_Bench/Cell/Cover/Cancer Cell/42_9.png,groundtruth,42_9.txt,MAC_Bench/Cell/Cover/Cancer Cell/23_2.png,MAC_Bench/Cell/Cover/Cancer Cell/23_2.png,vith,23_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/32_2.png,MAC_Bench/Cell/Cover/Cancer Cell/32_2.png,clip,32_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/22_1.png,MAC_Bench/Cell/Cover/Cancer Cell/22_1.png,vitg,22_1.txt,train
Current Biology,34_14,Which of the following options best describe the cover story?,"On the cover: In this issue, Chiarenza et al. reconstruct the evolution of dinosaur climatic niche, showing that ornithischians
and theropods developed broad climatic tolerances in the Early Jurassic, contrasting
with sauropodomorphs’ temperature conservatism. Broad niches in ornithischians and
theropods suggest “warm-bloodedness,” while sauropodomorphs' conservatism implies
“cold-bloodedness.” The dromaeosaurid theropod on the cover, which we reconstruct
as a likely homeotherm, is warming its nest amid a rigid and cold environment, evoking
the link between the evolution of thermophysiology and climate documented in this
paper. Image © Davide Bonadonna; used with permission.",C,MAC_Bench/Cell/Cover/Current Biology/27_4.png,MAC_Bench/Cell/Cover/Current Biology/27_4.png,clip,27_4.txt,MAC_Bench/Cell/Cover/Current Biology/32_19.png,MAC_Bench/Cell/Cover/Current Biology/32_19.png,vith,32_19.txt,MAC_Bench/Cell/Cover/Current Biology/34_14.png,MAC_Bench/Cell/Cover/Current Biology/34_14.png,groundtruth,34_14.txt,MAC_Bench/Cell/Cover/Current Biology/26_15.png,MAC_Bench/Cell/Cover/Current Biology/26_15.png,ave_1,26_15.txt,train
ACS Synthetic Biology,2025_1,Which of the following options best describe the cover story?,"The key economic indicators, namely, titer, rate, and yield (TRY) that, respectively, reflect the downstream processing, reactor size, and raw material costs, serve as useful ways to benchmark intensified fermentation processes. BioTRY provides a user-friendly interface for querying, browsing, and visualizing TRY records in microbial processes.",C,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_9.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_9.png,vitg,2023_9.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_1.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2012_5.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2012_5.png,ave_2,2012_5.txt,train
CELL RESEARCH,34_6,Which of the following options best describe the cover story?,"The SCN is the central biological clock with thousands of twinking neurons as the time-keeping elements. At the system level, bilaterally symmetrical ripple-like patterns emerge from the functional organization of these neurons, aesthetically pleasing like that of a butterfly.",B,MAC_Bench/Nature/Cover/CELL RESEARCH/33_11.png,MAC_Bench/Nature/Cover/CELL RESEARCH/33_11.png,ave_3,33_11.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_6.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_6.png,groundtruth,34_6.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,clip,34_10.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_5.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_5.png,ave_2,32_5.txt,train
Nature Electronics,7_6,Which of the following options best describe the cover story?,"Light-touch electronics with a spin
Imperceptible electronic fibres can be tethered to biological surfaces with an orbital spinning technique and used to create on-skin electrodes that can detect electrocardiogram signals, skin-gated organic electrochemical transistors, and augmented touch and plant interfaces. The photograph on the cover shows the fibres on one person’s finger, where they can be used to record electrocardiograms of another person by touching the other person’s finger.
See Wang et al. and News & Views by Wan et al.
Image: Wenyu Wang and Yuan Shui, University of Cambridge. Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Electronics/1_1.png,MAC_Bench/Nature/Cover/Nature Electronics/1_1.png,vitg,1_1.txt,MAC_Bench/Nature/Cover/Nature Electronics/4_10.png,MAC_Bench/Nature/Cover/Nature Electronics/4_10.png,clip,4_10.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_6.png,MAC_Bench/Nature/Cover/Nature Electronics/7_6.png,groundtruth,7_6.txt,MAC_Bench/Nature/Cover/Nature Electronics/6_5.png,MAC_Bench/Nature/Cover/Nature Electronics/6_5.png,vith,6_5.txt,val
ACS Biomaterials Science & Engineering,2025_1,Which of the following options best describe the cover story?,Morphology staining images of mouse oligodendrocyte progenitor cells cultured alongside electrospun fibers in 3D hydrogels. Cells grown alongside fibers extended numerous branchlike processes throughout the hydrogel.,A,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2025_1.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2015_6.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2015_6.png,vitg,2015_6.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2018_9.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2018_9.png,vith,2018_9.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2021_9.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2021_9.png,clip,2021_9.txt,val
Trends in Endocrinology & Metabolism,35_8,Which of the following options best describe the cover story?,"Recent advances in FGF21 biology and pharmacology have led to
clinical trials testing long-acting FGF21 analogues and antibody-based mimetics
for the treatment of obesity-related metabolic comorbidities. This month, Xu and
colleagues (pp 371—384) discuss the challenges and future directions in the clinical
implementation of FGF21-based drugs for metabolic disorders. The cover image
depicts a warrior fighting obesity-related comorbidities: his shield, showing the
structure of FGF21, symbolizes the protective roles of FGF21 analogues in alleviating
MASH and hypertriglyceridemia, whereas his knife and armor represent the therapeutic
potential of combination therapy based on FGF21 analogues and other hormones
against metabolic diseases. Artwork credit: Zara Siu Wa Chui.",B,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_14.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_14.png,vith,26_14.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_8.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_8.png,groundtruth,35_8.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_3.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_3.png,vitg,30_3.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/32_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/32_6.png,clip,32_6.txt,train
Nature Chemical Biology,20_10,Which of the following options best describe the cover story?,"Concentrated by condensates
Small molecules can concentrate in diverse cellular compartments. The image, captured by two-photon microscopy, shows the accumulation of tryptanthrin, a quinazoline indole alkaloid and active ingredient in medicinal herbs, within biomolecular condensates and cytoplasmic organelles.
See Kilgore et al.
Image: Henry Kilgore, Whitehead Institute for Biomedical Research. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_6.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_6.png,vith,14_6.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_7.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_7.png,clip,17_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_8.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_8.png,vitg,20_8.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_10.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_10.png,groundtruth,20_10.txt,test
Macromolecules,2025_2,Which of the following options best describe the cover story?,"Introducing a strategy to customize the dynamics of covalent adaptable networks via molecular-scale design. By modifying functional monomer moieties, this strategy adjusts vinylogous bond kinetics, enabling the properties of robustness, dynamics, shape-memory, reprocessibility, and degradation. View the article.",A,MAC_Bench/ACS/Cover/Macromolecules/2025_2.png,MAC_Bench/ACS/Cover/Macromolecules/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,ave_2,2014_20.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_19.png,MAC_Bench/ACS/Cover/Macromolecules/2010_19.png,clip,2010_19.txt,MAC_Bench/ACS/Cover/Macromolecules/2021_18.png,MAC_Bench/ACS/Cover/Macromolecules/2021_18.png,ave_1,2021_18.txt,train
NATURE BIOTECHNOLOGY,42_5,Which of the following options best describe the cover story?,"Liposomal antibiotics unleash antitumor immune response
An illustration of liposomal antibiotics (pink lipid particles) targeting tumor-associated bacteria (colored spheres in central purple tumor), leading to activation of T cells (white) by cytokines (orange) released from antigen-presenting cells (not shown). Wang et al. show that killing bacteria in tumors by liposomal delivery of antibiotics generates neoantigens that enhance T cell antitumor immunity in a mouse model of colon cancer.
See Wang et al.
Image: Ella Maru Studio. Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_12.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_12.png,vitg,39_12.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_5.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_5.png,groundtruth,42_5.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/22_5.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/22_5.png,vith,22_5.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/20_1.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/20_1.png,clip,20_1.txt,train
Macromolecules,2024_2,Which of the following options best describe the cover story?,Molecular dynamics simulations of crazes in glassy polymers under cyclic loading reveal the quasi-stress-free motion of craze fibril folding during unloading. View the article.,B,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_2.png,MAC_Bench/ACS/Cover/Macromolecules/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_18.png,MAC_Bench/ACS/Cover/Macromolecules/2010_18.png,ave_1,2010_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_23.png,MAC_Bench/ACS/Cover/Macromolecules/2014_23.png,vitg,2014_23.txt,train
Trendsin Neurosciences,47_12,Which of the following options best describe the cover story?,"Jumping spiders, renowned for their excellent vision used in prey capture,
navigation, and assessing elaborate, species-specific courtship displays, are an
emerging model system in the study of visual attention. These charismatic spiders
have
eight camera-type eyes: six function as motion detectors, while a pair of highly acute,
moveable eyes allow spiders to inspect the shape and color of objects. Historically,
investigation of visual processing in these animals has been thwarted by their internally
pressurized bodies, but these constraints have been overcome. In this issue of Trends
   in Neurosciences, Alex Winsor, Luke Remage-Healey, Ronald Hoy, and Elizabeth Jakob
highlight the architecture of the jumping spider visual system, discuss how shifts
in
gaze can regulate the uptake of visual information, and describe how different streams
of visual information from multiple eyes might be integrated in the brain. Cover image
of
Phidippus regius by Elizabeth Jakob.",A,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_12.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_12.png,groundtruth,47_12.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/34_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/34_5.png,clip,34_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,vith,43_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/34_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/34_9.png,vitg,34_9.txt,val
ACS Organic & Inorganic Au,2023_1,Which of the following options best describe the cover story?,"A tetrahedral chiral-at-nickel(II) complex has been synthesized using an achiral unsymmetric tridentate ligand, and its structural characteristics have been clarified in detail. Under a low-temperature condition, molecules with the same absolute configuration of the stereogenic nickel(II) center preferentially grow into conglomerate crystals due to the intermolecularly hydrogen-bonded helical structure formation.",B,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,groundtruth,2023_1.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_4.png,ave_2,2023_4.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,clip,2024_4.txt,train
Science Immunology,9_99,Which of the following options best describe the cover story?,"ONLINE COVER IgE Plasma Cells Are Cut from a Different Cloth. Immunoglobulin E–producing plasma cells (IgE PCs) are key players in allergic reactions and are an attractive target for the treatment of allergic diseases. A deeper understanding of IgE PC phenotypic and transcriptional profiles is needed, however. Vecchione et al. characterized IgE PCs from mice exposed to house dust mite allergen. IgE PCs were transcriptionally and phenotypically different from PCs producing other immunoglobulin isotypes, with increased endoplasmic reticulum stress due to higher levels of antibody production. IgE PCs in the lung-draining lymph node (dLN) and bone marrow (BM) showed distinct transcriptional profiles: The relatively short-lived IgE dLN PCs expressed genes indicative of recent class switching, whereas BM PCs were enriched for genes involved in survival and BM homing. This month’s cover illustration depicts plasma cells secreting a profusion of allergy-driving IgE antibodies. Credit: Noelle Burgess/Science Immunology",A,MAC_Bench/Science/Cover/Science Immunology/9_99.png,MAC_Bench/Science/Cover/Science Immunology/9_99.png,groundtruth,9_99.txt,MAC_Bench/Science/Cover/Science Immunology/9_95.png,MAC_Bench/Science/Cover/Science Immunology/9_95.png,vitg,9_95.txt,MAC_Bench/Science/Cover/Science Immunology/8_90.png,MAC_Bench/Science/Cover/Science Immunology/8_90.png,clip,8_90.txt,MAC_Bench/Science/Cover/Science Immunology/9_92.png,MAC_Bench/Science/Cover/Science Immunology/9_92.png,vith,9_92.txt,test
Caner Cell,42_6,Which of the following options best describe the cover story?,"On the cover: Casanova-Salas et al. demonstrate how the genomic and transcriptomic cargo within circulating extracellular
vesicles (EVs) from liquid biopsies provides valuable insights into metastatic prostate
cancer outcomes and treatment responses and how this information could facilitate
the identification of biomarkers for guiding therapy switch decisions. The cover artwork
features an EV-lit traffic light, symbolizing the important role that circulating
EVs could play in the trafficking of clinically actionable information. Image credit:
Carlos Córdoba Terreros.",C,MAC_Bench/Cell/Cover/Caner Cell/34_2.png,MAC_Bench/Cell/Cover/Caner Cell/34_2.png,vith,34_2.txt,MAC_Bench/Cell/Cover/Caner Cell/16_5.png,MAC_Bench/Cell/Cover/Caner Cell/16_5.png,vitg,16_5.txt,MAC_Bench/Cell/Cover/Caner Cell/42_6.png,MAC_Bench/Cell/Cover/Caner Cell/42_6.png,groundtruth,42_6.txt,MAC_Bench/Cell/Cover/Caner Cell/37_5.png,MAC_Bench/Cell/Cover/Caner Cell/37_5.png,clip,37_5.txt,train
Nature Metabolism,6_12,Which of the following options best describe the cover story?,"FASN cuts stress
In this issue of Nature Metabolism, Wei et al. identify a non-fatty acid synthesis function for FASN in suppressing diverse aspects of stress responses through a mechanism that involves FASN cleavage. Depicted are anesthetized C. elegans following stressful conditions.
See Wei et al.
Image: Hai Wei, UT Southwestern Medical Center. Cover Design: Thomas Phillips.",D,MAC_Bench/Nature/Cover/Nature Metabolism/3_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_12.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_12.png,ave_2,3_12.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_7.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_7.png,clip,3_7.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_12.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_12.png,groundtruth,6_12.txt,train
Journal of Agricultural and Food Chemistry,2025_4,Which of the following options best describe the cover story?,"This study investigates a novel antimicrobial peptide AtR905 derived from the endophytic fungus Aspergillus terreus, which was successfully expressed in",B,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2022_48.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2022_48.png,vitg,2022_48.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_4.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_51.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_51.png,clip,2021_51.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2024_45.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2024_45.png,vith,2024_45.txt,train
Organometallics,2025_4,Which of the following options best describe the cover story?,"s reactivity trend in activating C(spn)–X bonds mirrors that of a palladium catalyst. Reactivity increases by two distinct mechanisms: i) as the C(spn)–X bond becomes progressively weaker from X = F to Cl to Br to I, resulting in a more facile bond rupture, and ii) as the steric shielding at the pertinent carbon atom diminishes from C(sp3)–X to C(sp2)–X to C(sp)–X, leading to less steric clash and therefore a more stabilizing catalyst–substrate interaction.",D,MAC_Bench/ACS/Cover/Organometallics/2021_9.png,MAC_Bench/ACS/Cover/Organometallics/2021_9.png,clip,2021_9.txt,MAC_Bench/ACS/Cover/Organometallics/2024_16.png,MAC_Bench/ACS/Cover/Organometallics/2024_16.png,ave_1,2024_16.txt,MAC_Bench/ACS/Cover/Organometallics/2024_1.png,MAC_Bench/ACS/Cover/Organometallics/2024_1.png,ave_3,2024_1.txt,MAC_Bench/ACS/Cover/Organometallics/2025_4.png,MAC_Bench/ACS/Cover/Organometallics/2025_4.png,groundtruth,2025_4.txt,train
Trends in Cancer,11_2,Which of the following options best describe the cover story?,"In this issue, Kadali and Shoshani discuss the relationship between
abnormal nuclear structures and the formation of gene amplifications in cancer,
emphasizing their role in tumor heterogeneity and therapy resistance. The cover image
depicts cancer cells breaking chromosome bridges with amplified DNA, generating
ecDNA enclosed within micronuclei. These ecDNA-rich micronuclei, portrayed as
mobile carriers, travel along a winding road symbolizing the dynamic ""route to tumor
evolution."" Along this path, cancer cells act as builders or laborers, depositing
the
ecDNA-rich micronuclei into the tumor mass, highlighting their contribution to tumor
heterogeneity. Cover image design and illustration by Shilpa Madhavan.",B,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,vith,3_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/11_2.png,MAC_Bench/Cell/Cover/Trends in Cancer/11_2.png,groundtruth,11_2.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,vitg,10_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/6_5.png,MAC_Bench/Cell/Cover/Trends in Cancer/6_5.png,clip,6_5.txt,train
Journal of Medicinal Chemistry,2024_1,Which of the following options best describe the cover story?,"-A2B-corroles for photodynamic therapy of lung cancer. The lead photosensitizers showed remarkable properties, with IC50 values below 100 nM and no cytotoxicity per se, properties resulting from a synergy between the macrocyclic system and the hydrazone moiety.",C,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2019_8.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2019_8.png,clip,2019_8.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2023_13.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2023_13.png,vitg,2023_13.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_1.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_13.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_13.png,vith,2016_13.txt,val
ACS Chemical Neuroscience,2024_10,Which of the following options best describe the cover story?,"Induction of acetylation mediated by a CBP/p300-specific KAT activator, TTK21, conjugated to carbon nanosphere (CSP), administrated orally, promotes regeneration and functional recovery of spinal cord (green) injury (red) (partially created with BioRender.com).",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,clip,2022_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_12.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_12.png,ave_3,2022_12.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_1.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_1.png,ave_2,2023_1.txt,train
Molecular Pharmaceutics,2024_3,Which of the following options best describe the cover story?,Representation of the disordering effect induced by dibasic calcium phosphate (~the wrecking ball; CSD 31046-I) on carbamazepine dihydrate (~the wall; FEFNOT03) leading to its accelerated dehydration (~expelling of water molecules) during the mixing stage of continuous tablet manufacturing. This work focuses on understanding the mechanism of this excipient-induced effect. The image was created by PfizerWorks Creative Consultancy.,D,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_9.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_9.png,vitg,2021_9.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_3.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_3.png,vith,2021_3.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_1.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_1.png,clip,2021_1.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_3.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_3.png,groundtruth,2024_3.txt,train
ACS Chemical Neuroscience,2024_7,Which of the following options best describe the cover story?,"The mechanisms accounting for the formation of pores by amyloid peptides are revealed by unbiased all-atom simulations. Peptides adsorb, aggregate into β-sheets, and form pores spontaneously at the surface of lipid bilayers. Four peptides differing in the distribution of polar and nonpolar residues along the sequence are investigated.",B,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_8.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_10.png,vith,2020_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_3.png,vitg,2020_3.txt,val
Precision Chemistry,2025_1,Which of the following options best describe the cover story?,"Building two-dimensional, ordered carbon–carbon networks with precise, deterministic monomer coupling at the interface enables the creation of 2D porous, semiconducting nanomembranes.",A,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,vitg,2024_6.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,ave_1,2023_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,clip,2024_5.txt,train
NATURE REVIEWS IMMUNOLOGY,24_12,Which of the following options best describe the cover story?,"Myelin sheath repair, inspired by the Review on p49.
Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_1.png,vitg,14_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/15_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/15_3.png,clip,15_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_6.png,vith,19_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_12.png,groundtruth,24_12.txt,test
Nature Astronomy,8_7,Which of the following options best describe the cover story?,"The bated bang behind the burst
The brightest gamma-ray burst of all time, GRB 221009A, has a fairly modest supernova behind it, according to JWST observations. This finding demonstrates that the GRB and supernova mechanisms are decoupled, and suggests that other factors must be responsible for the extreme energetics involved.
See Blanchard et al.
Image: Aaron M. Geller, Northwestern, CIERA & IT Research Computing and Data Services. Cover design: Bethany Vukomanovic.",A,MAC_Bench/Nature/Cover/Nature Astronomy/8_7.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_7.png,groundtruth,8_7.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,vith,1_2.txt,MAC_Bench/Nature/Cover/Nature Astronomy/6_7.png,MAC_Bench/Nature/Cover/Nature Astronomy/6_7.png,vitg,6_7.txt,test
NATURE REVIEWS MOLECULAR CELL BIOLOGY,26_1,Which of the following options best describe the cover story?,"‘Understanding cell fate decisions’, inspired by the Review on p11
Cover design: Vicky Summersby",A,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.png,groundtruth,26_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/14_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/14_4.png,clip,14_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_7.png,vith,21_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_8.png,vitg,23_8.txt,train
NATURE ENERGY,9_11,Which of the following options best describe the cover story?,"Protecting the perovskite layer
The stability of perovskite solar cells under operating conditions remains a challenge. Suo et al. develop a sulfonium-based molecule that affords the perovskite material protection against environmental stress factors like moisture or light irradiation, showing solar cells with negligible efficiency loss after 4,500 hours of operation.
See Suo et al.
Image: Dmitry Bogachuk, Solarlab Aiko Europe. Cover design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/NATURE ENERGY/9_11.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_11.png,groundtruth,9_11.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/4_2.png,MAC_Bench/Nature/Cover/NATURE ENERGY/4_2.png,vith,4_2.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/7_6.png,MAC_Bench/Nature/Cover/NATURE ENERGY/7_6.png,clip,7_6.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/7_1.png,MAC_Bench/Nature/Cover/NATURE ENERGY/7_1.png,ave_2,7_1.txt,train
Nature Reviews Materials,9_8,Which of the following options best describe the cover story?,"Memristors are two-terminal devices that display memory in the form of electrical resistance. Solution-processed memristors are arising as an attractive technology enabled by the versatility of solution-processed materials, but conscious analysis and demonstration of their performance and reliability are required to enable practical applications. The cover art depicts the opportunity presented by solution-processed methods to synthesize different materials (metal oxides, 2D materials, polymers) to build memristors for potential use in cryptography, data storage and artificial intelligence. See Pazos S et al.
Cover: David Johnston. The 2D material model is adapted from is adapted from Chen C. et al, Cancer Nanotechnology 13,29 (2022), CC BY 4.0",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_11.png,clip,4_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_5.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_5.png,vitg,8_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/1_7.png,ave_2,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,groundtruth,9_8.txt,train
Industrial & Engineering Chemistry Research,2024_30,Which of the following options best describe the cover story?,"This paper presents different machine learning algorithms used to predict the production and characteristics of aligned electrospun nanofibers fabricated by the air gap electrospinning method. Classification and regression models are developed using logistic regression, random forest, artificial neural networks, and convolutional neural networks.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_51.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_51.png,clip,2022_51.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_30.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_30.png,groundtruth,2024_30.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_6.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_6.png,vitg,2022_6.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_27.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_27.png,vith,2022_27.txt,train
ACS Earth and Space Chemistry,2024_3,Which of the following options best describe the cover story?,"We evaluate the diversity of volatile organic compounds (VOCs) emitted from both pre- and post-harvest 'Alkar' tall wheatgrass, a candidate biofuel. While green leaf volatiles dominate post-harvest emissions, we demonstrate novel post-harvest VOCs that are under-characterized in the context of carbon cycling and atmospheric chemistry.",C,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_11.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_11.png,ave_2,2022_11.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_4.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_4.png,clip,2022_4.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_3.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_10.png,vitg,2022_10.txt,train
ACS Food Science & Technology,2024_9,Which of the following options best describe the cover story?,Controlling the postprandial glucose spike by increasing the rich starch crystallinity and lowering the starch digestion rate of rice-based fermented foods using a combination of heat treatment and hydrocolloid addition.,A,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_9.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_8.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_8.png,vith,2022_8.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,clip,2022_11.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,ave_1,2023_2.txt,train
Nature Biomedical Engineering,9_1,Which of the following options best describe the cover story?,"Potent and safer editing via nanoparticle-delivered ribonucleoprotein
This issue highlights advances in genome editing, including the enhancement of the efficiency and precision of base editing and prime editing, the optimization of the delivery of genome editors and the reduction of off-target effects.
The cover illustrates lipid nanoparticles optimized for enhancing the stability, delivery efficiency and editing potency of ribonucleoproteins for base editing and prime editing.
See Hołubowicz et al.
Image: Image courtesy of Samuel W. Du, University of California, Irvine and Yekaterina Kadyzhevskaya, University of Southern California. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/6_11.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/6_11.png,clip,6_11.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/9_1.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_8.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_8.png,vith,8_8.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_11.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_11.png,vitg,5_11.txt,train
Caner Cell,43_1,Which of the following options best describe the cover story?,"On the cover: The cover illustrates how glioblastoma (GBM) aligns its growth with
the brain's daily rhythms. Inspired by artist Sophie Taeuber-Arp and designed by Dr.
Olivia Walch, this visual highlights the daytime tumor growth driven by the circadian
surge in glucocorticoids (green dots). Gonzalez-Aponte et al. discover that blocking circadian regulation of glucocorticoid receptor signaling
slows GBM proliferation in both mouse and human GBM models. Targeting circadian mechanisms
to combat GBM holds great promise and has significant implications for understanding
how the circadian system may influence cancer progression, both within the brain and
beyond.",B,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,ave_2,33_2.txt,MAC_Bench/Cell/Cover/Caner Cell/43_1.png,MAC_Bench/Cell/Cover/Caner Cell/43_1.png,groundtruth,43_1.txt,MAC_Bench/Cell/Cover/Caner Cell/26_5.png,MAC_Bench/Cell/Cover/Caner Cell/26_5.png,clip,26_5.txt,MAC_Bench/Cell/Cover/Caner Cell/28_4.png,MAC_Bench/Cell/Cover/Caner Cell/28_4.png,vith,28_4.txt,test
Journal of Chemical Education,2021_5,Which of the following options best describe the cover story?,"In ""Chiroptical Smart Paints: Polymerization of Helical Structures in Cholesteric Liquid Crystal Films"" (",A,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_5.png,groundtruth,2021_5.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_1.png,ave_1,2021_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2020_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2020_11.png,vitg,2020_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2020_10.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2020_10.png,clip,2020_10.txt,val
Science Signaling,2007_387,Which of the following options best describe the cover story?,"COVER This week features a Book Review of Regulation of Gene Expression in Plants: The Role of Transcript Structure and Processing, edited by Carole L. Bassett. The image depicts maize with stripes resulting from the movement of transposons. [Image: Alan Rose, University of California, Davis]",C,MAC_Bench/Science/Cover/Science Signaling/11_536.png,MAC_Bench/Science/Cover/Science Signaling/11_536.png,clip,11_536.txt,MAC_Bench/Science/Cover/Science Signaling/5_236.png,MAC_Bench/Science/Cover/Science Signaling/5_236.png,vith,5_236.txt,MAC_Bench/Science/Cover/Science Signaling/2007_387.png,MAC_Bench/Science/Cover/Science Signaling/2007_387.png,groundtruth,2007_387.txt,MAC_Bench/Science/Cover/Science Signaling/1_15.png,MAC_Bench/Science/Cover/Science Signaling/1_15.png,vitg,1_15.txt,train
Nature Aging,4_7,Which of the following options best describe the cover story?,"Stochasticity in epigenetic clocks
In this issue, three studies examine the contribution of stochastic epigenetic changes to DNA methylation clocks. Tarkhov et al., Meyer et al. and Tong et al. take different approaches to addressing this question, and concur that stochasticity is involved in epigenetic aging. The cover, from Meyer et al., shows a Galton board, which is a device used to illustrate concepts of probability and stochasticity. At the top, a series of small balls are released, which follow a random path before landing in bins at the bottom. Over many trials, this stochastic process leads to the formation of a normal distributed shape. A clock is depicted within this shape to illustrate that a completely stochastic process can be used to construct aging clocks, consistent with a role of age-dependent increases in stochastic variation in epigenetic processes.
See Tarkhov et al., Meyer et al. & Tong et al.
Image: Maayan Visuals. Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,ave_3,4_11.txt,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,ave_2,4_8.txt,MAC_Bench/Nature/Cover/Nature Aging/4_7.png,MAC_Bench/Nature/Cover/Nature Aging/4_7.png,groundtruth,4_7.txt,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,clip,1_1.txt,test
Science Translational Medicine,17_781,Which of the following options best describe the cover story?,"ONLINE COVER A Noble Pursuit. The cover image shows brain microglia (green) in an intermediate activation state engaging with amyloid plaques (white) in brain tissue from a mouse model of Alzheimer’s disease (AD). Microglia were induced to transition to an intermediate activation state by exposing mice with AD pathology to the anesthetic xenon (Brandao et al.). Xenon, a noble gas, crossed the blood-brain barrier of the mice and promoted microglial activation through interferon-γ signaling. Inhalation of xenon enhanced amyloid plaque compaction in the mouse brain, reduced the number of dystrophic neurites, reduced brain atrophy, and slowed neurodegeneration in three different mouse models of AD. Xenon shows promise as a potential therapeutic for treating AD. Credit: Brandao et alMAC_Bench/Science Translational Medicine",C,MAC_Bench/Science/Cover/Science Translational Medicine/5_206.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_206.png,vitg,5_206.txt,MAC_Bench/Science/Cover/Science Translational Medicine/13_613.png,MAC_Bench/Science/Cover/Science Translational Medicine/13_613.png,clip,13_613.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_781.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_781.png,groundtruth,17_781.txt,MAC_Bench/Science/Cover/Science Translational Medicine/12_563.png,MAC_Bench/Science/Cover/Science Translational Medicine/12_563.png,vith,12_563.txt,train
Journal of the American Chemical Society,2024_8,Which of the following options best describe the cover story?,"Crystal structure solution methods powered by recent advancements in machine learning reveal the structures of compounds that were previously unsolved. Crystalyze, a model for solving structures from powder X-ray diffraction, has discovered several materials and promises to serve as a generalizable tool for materials discovery under a wide range of conditions. View the article.",A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_8.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_16.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_16.png,vitg,2009_16.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_11.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_11.png,vith,2016_11.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_4.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_4.png,clip,2018_4.txt,val
Science Immunology,9_92,Which of the following options best describe the cover story?,"ONLINE COVER Treating a Primary Immunodeficiency with CRISPR. Familial hemophagocytic lymphohistiocytosis (FHL) is a range of inherited, sometimes fatal, inflammatory diseases caused by loss-of-function mutations in the cytotoxic machinery of immune cells. Li et al. developed an adeno-associated virus (AAV)–based CRISPR–Cas9 system combined with nonhomologous end joining (NHEJ) inhibition to repair memory T cells from perforin (Prf1)-deficient mice as well as from pediatric patients with FHL2 (PRF1 deficiency) or FHL3 (Munc13-4/UNC13D deficiency). Repaired mouse T cells could then prevent or cure FHL2-like disease in Prf1-knockout mice triggered by Epstein–Barr virus (EBV)–driven B cell hyperproliferation. This month’s cover illustration depicts CRISPR–Cas9–mediated repair of a cytotoxic T cell (red), which allows it to secrete normal cytotoxic granules (pink) and effectively kill virally infected B cells (blue). Credit: A. Fisher/Science Immunology",B,MAC_Bench/Science/Cover/Science Immunology/3_28.png,MAC_Bench/Science/Cover/Science Immunology/3_28.png,clip,3_28.txt,MAC_Bench/Science/Cover/Science Immunology/9_92.png,MAC_Bench/Science/Cover/Science Immunology/9_92.png,groundtruth,9_92.txt,MAC_Bench/Science/Cover/Science Immunology/4_34.png,MAC_Bench/Science/Cover/Science Immunology/4_34.png,vitg,4_34.txt,MAC_Bench/Science/Cover/Science Immunology/6_56.png,MAC_Bench/Science/Cover/Science Immunology/6_56.png,vith,6_56.txt,train
BDJ In Practice,37_8,Which of the following options best describe the cover story?,"In this May issue...
Technology is here to stay, and for those early adopters, you're likely reaping the rewards. For those unwilling or unable, this issue's cover feature digs into what's around the corner in the hope of trickledown technology
Cover illustration by Tim Marrs",D,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,vitg,35_8.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,vith,37_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_9.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_9.png,clip,36_9.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_8.png,groundtruth,37_8.txt,train
NATURE REVIEWS CANCER,24_2,Which of the following options best describe the cover story?,"Forces that squeeze, inspired by the Review on p768.
Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_2.png,groundtruth,24_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,vith,17_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_6.png,clip,24_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_3.png,vitg,23_3.txt,val
Nature Human Behaviour,8_8,Which of the following options best describe the cover story?,"Chimpanzee social learning
Is know-how copying a uniquely human capacity? Van Leeuwen and colleagues demonstrate that chimpanzees use social learning to acquire a skill that they failed to innovate, which suggests that chimpanzees — like humans — use know-how copying to expand their skill set.
See Van Leeuwen et al.
Image: Chimfunshi Wildlife Orphanage and Clara Dubois. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_4.png,clip,4_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_2.png,ave_3,5_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_4.png,ave_2,5_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_8.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_8.png,groundtruth,8_8.txt,train
NATURE MATERIALS,23_10,Which of the following options best describe the cover story?,"Growing tunable moirés
Two-dimensional structures with tunable moiré patterns, which display tunable interlayer excitons and moiré intralayer excitons, are achieved by epitaxial bottom-up growth.
See Fortin-Deschênes et al.
Image: Yihao Song and Matthieu Fortin-Deschênes, Yale University. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_10.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_10.png,groundtruth,23_10.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_5.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_5.png,vith,20_5.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_3.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_3.png,clip,21_3.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_2.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_2.png,vitg,22_2.txt,train
Cell Reports Physical Science,5_10,Which of the following options best describe the cover story?,"On the cover: Xie et al. report their investigation of the oxidative Nazarov reaction and its application
to the collective synthesis of five fusicoccane diterpenoids. To celebrate the Chinese
New Year, a traditional Chinese-style illustration named “Two Loongs Playing with
a Pearl” is presented to indicate that the oxidative Nazarov reaction is a robust
synthetic method and a valuable tool for natural product synthesis. Image by Yan Qiu.",D,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,vitg,2_9.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_3.png,clip,3_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,vith,5_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_10.png,groundtruth,5_10.txt,train
Nature Astronomy,8_3,Which of the following options best describe the cover story?,"Decoding a galaxy’s past with AI
Constraining the intrinsic and extrinsic stellar mass in a galaxy unlocks its merger history. Here, using the power of artificial intelligence, the authors do this for 10,000 galaxies, finding traits that can be used to characterize even larger samples.
See Angeloudi et al.
Image: Gabriel Pérez Díaz (Instituto de Astrofísica de Canarias), image background: NASA/ESA/STScI. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Astronomy/7_12.png,MAC_Bench/Nature/Cover/Nature Astronomy/7_12.png,ave_2,7_12.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_1.png,vitg,8_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_3.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_3.png,groundtruth,8_3.txt,test
ACS Applied Nano Materials,2025_7,Which of the following options best describe the cover story?,"Gold nanoclusters embedded in cross-linked lysozyme crystals exhibit enzyme activity that depends on available diffusion channels and solvent accessibility. When the morphology allows efficient diffusion, gold nanoclusters with lysozyme can serve as tandem catalysts, functioning as both peroxidase and hydrolytic enzymes, showcasing their potential in diverse catalytic applications.",B,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2019_7.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2019_7.png,vitg,2019_7.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_7.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_5.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_5.png,clip,2020_5.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_23.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_23.png,ave_3,2023_23.txt,train
Current Biology,34_21,Which of the following options best describe the cover story?,"On the cover: How does a single cell control its behavior? This is Euplotes, a unicellular organism with a highly complex morphology. The thick bundles of cilia
called cirri (seen here on the cover) emanating from its lower surface are used for
walking and swimming. In this issue, Laeverenz-Schlogelhofer and Wan demonstrate the bioelectrical basis for gait control in this walking single cell.
Simultaneous electrophysiological recordings and high-speed imaging reveal that membrane
potential regulates cirri activity, enabling Euplotes to rapidly switch between forward walking and turning. Depolarization events orchestrate
the cell's highly coordinated turning maneuver, with distinct cirri behaving differently.
SEM micrograph by Christian Hacker; used with permission.",C,MAC_Bench/Cell/Cover/Current Biology/27_17.png,MAC_Bench/Cell/Cover/Current Biology/27_17.png,vitg,27_17.txt,MAC_Bench/Cell/Cover/Current Biology/20_16.png,MAC_Bench/Cell/Cover/Current Biology/20_16.png,vith,20_16.txt,MAC_Bench/Cell/Cover/Current Biology/34_21.png,MAC_Bench/Cell/Cover/Current Biology/34_21.png,groundtruth,34_21.txt,MAC_Bench/Cell/Cover/Current Biology/31_2.png,MAC_Bench/Cell/Cover/Current Biology/31_2.png,clip,31_2.txt,train
Science Robotics,9_97,Which of the following options best describe the cover story?,"ONLINE COVER Artificial Intelligence—Solving Decision-Making Problems in Dynamical Systems. Autonomous robots need the ability to adaptively make decisions in unstructured and dynamic environments. Rivière et al. have now developed Spectral Expansion Tree Search, a real-time space planning algorithm that can construct representations of the real world and converge to optimal solutions, enabling autonomous robot decision-making in complex environments. They demonstrated the ability of their framework experimentally with aerial and ground robots with the potential to discover optimal trajectories in complex environments. This month’s cover is an image of a robot mimicking a spacecraft deployed with their framework in a simulated frictionless environment. Credit: Vicki Chiu",C,MAC_Bench/Science/Cover/Science Robotics/4_30.png,MAC_Bench/Science/Cover/Science Robotics/4_30.png,vitg,4_30.txt,MAC_Bench/Science/Cover/Science Robotics/8_78.png,MAC_Bench/Science/Cover/Science Robotics/8_78.png,vith,8_78.txt,MAC_Bench/Science/Cover/Science Robotics/9_97.png,MAC_Bench/Science/Cover/Science Robotics/9_97.png,groundtruth,9_97.txt,MAC_Bench/Science/Cover/Science Robotics/6_61.png,MAC_Bench/Science/Cover/Science Robotics/6_61.png,clip,6_61.txt,train
Nature Chemical Biology,20_4,Which of the following options best describe the cover story?,"Specificity for cathepsin S
The structure of non-natural peptide inhibitors can be rapidly optimized to specifically block the activity of protease targets. The cover image depicts different non-natural peptides bound to the molecular structure of cathepsin S, representing a few possible outcomes of site saturation mutagenesis screening.
See Petruzzella et al.
Image: Aaron Petruzzella, EPFL. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Chemical Biology/19_5.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/19_5.png,clip,19_5.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_10.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_10.png,vith,18_10.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_4.png,groundtruth,20_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_4.png,vitg,15_4.txt,train
Journal of the American Chemical Society,2024_45,Which of the following options best describe the cover story?,"Lasso peptides are a promising scaffold for small therapeutics with thermal and proteolytic stability. Simulations reveal that de novo folding is possible and can be stabilized through sequence and chemical modifications, opening the door to the chemical synthesis of lasso structures.",B,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_36.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_36.png,vith,2009_36.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_45.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_45.png,groundtruth,2024_45.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_4.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_4.png,vitg,2018_4.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_19.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_19.png,clip,2009_19.txt,train
Nature Cardiovascular Research,3_10,Which of the following options best describe the cover story?,"Neutralizing gremlins protects against myocarditis
Perez-Shibayama et al. report that restoring BMP4 signaling with antibodies that neutralize the BMP inhibitors gremlin-1 and gremlin-2 can ameliorate myocarditis by reducing immune cell infiltration, the production of pathogenic cytokines, and pro-inflammatory activity in fibroblasts.
See Perez-Shibayama et al.
Image: Nadine Cadosch, Kantonsspital St. Gallen, St. Gallen, Switzerland. Cover design: Bethany Vukomanovic.",D,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_11.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_11.png,clip,1_11.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_10.png,groundtruth,3_10.txt,train
Science Translational Medicine,17_785,Which of the following options best describe the cover story?,"ONLINE COVER Expanding Liver Gene Editing. The cover shows gene-targeted and expanded adult mouse hepatocytes (red) and a counterstain for DNA (blue). Homology-directed repair (HDR)-based techniques show promise for gene editing of liver diseases, but they do not always achieve sufficient editing of adult cells. To improve HDR-based hepatocyte editing, De Giorgi et al. created a system that conditions the liver by transiently knocking down the essential gene fumarylacetoacetate hydrolase (Fah), and then inserts a therapeutic transgene of choice alongside a non-targetable version of Fah into the highly expressed Apolipoprotein A1 (Apoa1) locus, to protect the hepatocytes from further injury. A high-protein diet in these mice increased expansion of edited hepatocytes and corrected of about a quarter of all hepatocytes in the liver, and increased the expression of therapeutic transgene human factor IX (FIX) by five-fold. This increased expansion of targeted hepatocytes may expand the number of liver diseases targetable by gene therapy. Credit: Marco De Giorgi",B,MAC_Bench/Science/Cover/Science Translational Medicine/15_715.png,MAC_Bench/Science/Cover/Science Translational Medicine/15_715.png,clip,15_715.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_785.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_785.png,groundtruth,17_785.txt,MAC_Bench/Science/Cover/Science Translational Medicine/13_601.png,MAC_Bench/Science/Cover/Science Translational Medicine/13_601.png,ave_0,13_601.txt,MAC_Bench/Science/Cover/Science Translational Medicine/5_174.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_174.png,vitg,5_174.txt,train
ACS Earth and Space Chemistry,2024_7,Which of the following options best describe the cover story?,A range of cationic hydroxylated silicon oxide species are produced and their infrared (IR) spectra are,A,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_7.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_8.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_8.png,ave_1,2023_8.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_4.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_4.png,vitg,2022_4.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_1.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_1.png,clip,2024_1.txt,train
Cancer Cell,42_6,Which of the following options best describe the cover story?,"On the cover: Casanova-Salas et al. demonstrate how the genomic and transcriptomic cargo within circulating extracellular
vesicles (EVs) from liquid biopsies provides valuable insights into metastatic prostate
cancer outcomes and treatment responses and how this information could facilitate
the identification of biomarkers for guiding therapy switch decisions. The cover artwork
features an EV-lit traffic light, symbolizing the important role that circulating
EVs could play in the trafficking of clinically actionable information. Image credit:
Carlos Córdoba Terreros.",B,MAC_Bench/Cell/Cover/Cancer Cell/37_5.png,MAC_Bench/Cell/Cover/Cancer Cell/37_5.png,clip,37_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_6.png,MAC_Bench/Cell/Cover/Cancer Cell/42_6.png,groundtruth,42_6.txt,MAC_Bench/Cell/Cover/Cancer Cell/16_5.png,MAC_Bench/Cell/Cover/Cancer Cell/16_5.png,vitg,16_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/34_2.png,MAC_Bench/Cell/Cover/Cancer Cell/34_2.png,vith,34_2.txt,train
Nature Reviews Nephrology,20_2,Which of the following options best describe the cover story?,"Drug repurposing, inspired by the Review on p707.
Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_2.png,groundtruth,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,clip,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_5.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_5.png,vitg,18_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,vith,17_8.txt,val
Cell Metabolism,36_5,Which of the following options best describe the cover story?,"On the cover: Th17 cells are essential for protecting the gut from infections and
maintaining mucosal immunity. Bonetti et al. demonstrate that glutathione (GSH)-mediated control of mitochondrial reactive oxygen
species (mROS) is critical for Th17 cell function. Accumulation of ROS in Th17 cells
disrupts mitochondrial transcription and energy production, which is linked to the
translation of IL-22. Unlike IL-17, GSH-regulated IL-22 prevents the spread of bacteria
to peripheral organs. On the cover, the complex interplay between GSH and ROS in Th17
cells within the intestine is depicted as a crossword puzzle. While IL-17 initially
appears to be the correct answer, it is crossed out and replaced by IL-22, which is
important for the maintenance of functional intestinal homeostasis. Picture by Lynn
Bonetti.",B,MAC_Bench/Cell/Cover/Cell Metabolism/15_4.png,MAC_Bench/Cell/Cover/Cell Metabolism/15_4.png,vitg,15_4.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_5.png,groundtruth,36_5.txt,MAC_Bench/Cell/Cover/Cell Metabolism/12_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/12_3.png,vith,12_3.txt,MAC_Bench/Cell/Cover/Cell Metabolism/17_1.png,MAC_Bench/Cell/Cover/Cell Metabolism/17_1.png,clip,17_1.txt,test
Nature Reviews Nephrology,20_1,Which of the following options best describe the cover story?,"Amino acid metabolism, inspired by the Review on p771.
Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,groundtruth,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_3.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_3.png,ave_3,17_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_6.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_6.png,clip,19_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_10.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_10.png,vith,17_10.txt,train
Molecular Therapy,32_15,Which of the following options best describe the cover story?,"On the cover: Pyroptosis is an inflammatory form of programmed cell death that occurs upon infection.
Kou and colleagues revealed that pyroptotic cells generate a new group of pyroptotic extracellular vesicles
(pyroEVs) and uncover the therapeutic effect of mesenchymal stem cell-derived pyroEVs
on sepsis. Specific expressed ASC can serve as a functional marker identifying exogenous
and endogenous pyroEVs and mediating the protective effect of pyroEV on B cells. In
this image, even the “fiery falling” pyroptotic cells will generate small nutrient
vesicles to protect the damaged host B cells during infection, thus rescuing sepsis.
Image credit: Suqian Qinyan Information Technology Co., LTD.",B,MAC_Bench/Cell/Cover/Molecular Therapy/25_5.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_5.png,clip,25_5.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_15.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_15.png,groundtruth,32_15.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_3.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_3.png,vith,31_3.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_8.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_8.png,vitg,31_8.txt,train
ACS Catalysis,2024_20,Which of the following options best describe the cover story?,"Pulsed-laser decoration of single Pd nanoparticles on NiCo2O4 nanoplates resulted in a Pd/NiCo2O4 composite with excellent bifunctional electrocatalytic activity in both the hydrogen evolution reaction and the hydrazine oxidation reaction. Accordingly, the assembled hybrid electrolyzer achieves low-voltage-driven hydrogen production while simultaneously degrading hydrazine in wastewater into nitrogen, effectively achieving dual objectives with a single strategy.",D,MAC_Bench/ACS/Cover/ACS Catalysis/2017_10.png,MAC_Bench/ACS/Cover/ACS Catalysis/2017_10.png,vitg,2017_10.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_11.png,clip,2024_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2023_1.png,MAC_Bench/ACS/Cover/ACS Catalysis/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_20.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_20.png,groundtruth,2024_20.txt,val
Cell Reports Physical Science,6_2,Which of the following options best describe the cover story?,"On the cover: A visual celebration of Cell Reports Physical Science’s fifth anniversary, featuring all of our covers from Volume 1, Issue 1 to December
2024’s Volume 5, Issue 12. We’d like to thank Cell Press’s own Philip Krzeminski for
his help in creating this beautiful cover.",A,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_2.png,groundtruth,6_2.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_2.png,clip,5_2.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_6.png,ave_0,4_6.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_1.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_1.png,vitg,6_1.txt,train
ACS Agricultural Science & Technology,2024_2,Which of the following options best describe the cover story?,"The image shows Khasi mandarin oranges inside a container, connected to sensors measuring their ripeness and respiration rate. This study uses AI to predict how long the fruit will stay fresh, helping to make better decisions for storage, pricing, and reducing waste.",D,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_6.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_6.png,vitg,2022_6.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2021_6.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2021_6.png,clip,2021_6.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_2.png,vith,2023_2.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_2.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_2.png,groundtruth,2024_2.txt,train
Nature Geoscience,18_1,Which of the following options best describe the cover story?,"High mountain hazard cascade
Perched at 3,600 m elevation in the Himalayan mountains of Nepal, massive glacial sediment deposits were incised by nearly 100 m in a geological instant during monsoonal flooding in 2021. The sediment unleashed by this event set in motion an erosional chain reaction with devastating consequences downstream, exemplifying the cascading hazard posed by sediment-laden floods in high mountains.
See Chen et al.
Image: Chan-Mao Chen, University of Southern California. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Geoscience/6_12.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_12.png,clip,6_12.txt,MAC_Bench/Nature/Cover/Nature Geoscience/15_6.png,MAC_Bench/Nature/Cover/Nature Geoscience/15_6.png,ave_3,15_6.txt,MAC_Bench/Nature/Cover/Nature Geoscience/14_12.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_12.png,ave_2,14_12.txt,MAC_Bench/Nature/Cover/Nature Geoscience/18_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/18_1.png,groundtruth,18_1.txt,train
Nature Mental Health,2_11,Which of the following options best describe the cover story?,"Climate mental health
The February cover is a moody depiction of climate mental health. Intended to invoke the idea of the interplay among Gaia (the spirit of Earth), nature and humanity, the blue tones also reference the Connecting Climate Minds project. As a means for placing mental health prominently in climate agendas, this initiative is a catalyst for invigorating the broader climate mental health field.
See our Editorial for more on the emerging field of climate mental health
Image: Rebeka Ryvola/Climate Cares Centre. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,clip,2_3.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,groundtruth,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,ave_2,2_5.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,vitg,2_6.txt,train
Nature Reviews Rheumatology,20_4,Which of the following options best describe the cover story?,"Inspired by the Review on p531.
Cover design: Steven Hall",B,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_4.png,groundtruth,20_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,train
Cell Stem Cell,31_4,Which of the following options best describe the cover story?,"On the cover: In some mammalian species, the blastocyst-stage embryo suspends its
development and enters a state of “deep sleep” (embryo dormancy or diapause). The
cover image depicts a dreamcatcher with an integrated embryo pattern in the center
to symbolize this peculiar state. In addition to dormancy, the round shape of the
dreamcatcher symbolizes the maternal environment (uterine tube) illustrating that
an analysis of this state by Chen et al. has been performed in physiological conditions. Moreover, the interconnected nodes
in the dreamcatcher symbolize the gene networks identified by single-cell sequencing.
Image courtesy of the authors.",B,MAC_Bench/Cell/Cover/Cell Stem Cell/6_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_2.png,vitg,6_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_4.png,groundtruth,31_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/29_3.png,MAC_Bench/Cell/Cover/Cell Stem Cell/29_3.png,clip,29_3.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/12_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/12_2.png,ave_2,12_2.txt,test
ACS Central Science,2024_7,Which of the following options best describe the cover story?,"Shown in cartoon form is the key finding described by Yang et al., namely, that electron transfer between two pyrrole-based macrocycles and iodine can be readily controlled through the judicious choice of small molecule “players” and variations in the concentration. This work advances our understanding of fundamentals relevant to energy, catalysis, and molecular electronics.",A,MAC_Bench/ACS/Cover/ACS Central Science/2024_7.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,vith,2024_2.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_9.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_9.png,vitg,2024_9.txt,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,clip,2025_2.txt,train
Macromolecules,2024_17,Which of the following options best describe the cover story?,Bottlebrush polymers with helical and nonhelical sidechains (tuned by the monomer chirality) impact the backbone breadth in solution and the rate of mechanochemistry. View the article.,B,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_17.png,MAC_Bench/ACS/Cover/Macromolecules/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_18.png,MAC_Bench/ACS/Cover/Macromolecules/2022_18.png,vith,2022_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,vitg,2014_20.txt,test
Cell Systems,15_11,Which of the following options best describe the cover story?,"On the cover: Lung cancer cells expressing the CluMPS reporter (magenta) show large
puncta that indicate the presence of small, hard-to-see clusters of its target (EML4-ALK,
green). In this issue of Cell Systems, Mumford et al. introduce CluMPS (clusters magnified by phase separation), a fluorescent reporter
for detecting small protein clusters in living cells. The combined multivalency of
CluMPS and a multimerized target produces large condensates that are detectable with
standard microscopy. CluMPS can detect and track clusters of both endogenous and exogenous
proteins. Image credit: Thomas Mumford.",A,MAC_Bench/Cell/Cover/Cell Systems/15_11.png,MAC_Bench/Cell/Cover/Cell Systems/15_11.png,groundtruth,15_11.txt,MAC_Bench/Cell/Cover/Cell Systems/5_4.png,MAC_Bench/Cell/Cover/Cell Systems/5_4.png,clip,5_4.txt,MAC_Bench/Cell/Cover/Cell Systems/13_3.png,MAC_Bench/Cell/Cover/Cell Systems/13_3.png,vith,13_3.txt,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,vitg,1_2.txt,test
Med,5_7,Which of the following options best describe the cover story?,"On the cover: This issue of Med explores the applications of CAR T cell therapies beyond hematologic malignancies,
including solid tumors and autoimmune diseases. A Q&A with Fabian Müller (University Hospital Erlangen) covers the latest developments in the field. A Review
from Liu et al. discusses emerging combination strategies using CAR T cells in solid tumors, while
Shu et al. review the exciting potential of CAR technology in non-neoplastic diseases. Fischbach et al. present a Case Report describing the safety and feasibility of CD19-targeted CAR
T-cell therapy in the first two patients with progressive multiple sclerosis, with
an accompanying Viewpoint from Rankin and Shah highlighting the new frontiers of CAR T cell therapies. Cover credit: Keith Chambers/Science
Photo Library via Getty Images.",C,MAC_Bench/Cell/Cover/Med/4_6.png,MAC_Bench/Cell/Cover/Med/4_6.png,vith,4_6.txt,MAC_Bench/Cell/Cover/Med/2_4.png,MAC_Bench/Cell/Cover/Med/2_4.png,vitg,2_4.txt,MAC_Bench/Cell/Cover/Med/5_7.png,MAC_Bench/Cell/Cover/Med/5_7.png,groundtruth,5_7.txt,MAC_Bench/Cell/Cover/Med/5_9.png,MAC_Bench/Cell/Cover/Med/5_9.png,clip,5_9.txt,train
Trends in Chemistry,6_1,Which of the following options best describe the cover story?,"All materials contain defects that can change their stability, characteristics
and behaviour. Computational simulations of these defects can help scientists to more
accurately predict their occurrence, concentration and resultant chemical properties.
In
their Forum article in this issue, Gormley and Hendon examine the nuances of calculating
defect formation energetics in molecular materials, with a focus on highlighting some
of the strategies theorists can use specifically to treat the chemical potential and
correctional terms of the calculation. Better predictions can help make these calculations
a crucial tool in the design and understanding of new materials. Cover image credit:
GettyImages/Tom Gowanlock",B,MAC_Bench/Cell/Cover/Trends in Chemistry/4_1.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_1.png,vith,4_1.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_1.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_1.png,groundtruth,6_1.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/3_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/3_8.png,vitg,3_8.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/2_10.png,MAC_Bench/Cell/Cover/Trends in Chemistry/2_10.png,clip,2_10.txt,train
ACS Sustainable Chemistry & Engineering,2025_2,Which of the following options best describe the cover story?,Self-assembly of cellulose nanocrystals (CNCs) synthesized from rice straw yields transparent films with distinct structural colors. Amine modification of CNCs significantly improves the electron mobility and current–voltage characteristics. The transreflective property and photoresponsivity of,D,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_47.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_47.png,vitg,2021_47.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_3.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_3.png,vith,2015_3.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_7.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_7.png,clip,2015_7.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_2.png,groundtruth,2025_2.txt,test
Analytical Chemistry,2025_2,Which of the following options best describe the cover story?,"3D-printed dual-channel flow-through miniaturized devices (3Dd) with dual electrochemical detection (EDd) integrating two working electrodes each in an in-channel configuration (3Dd–EDd), are combined with the rich PB-based electrochemistry to obtain reliable, stable, and ready-to-use devices with excellent analytical performance toward hydrogen peroxide detection in cultivar cells.",D,MAC_Bench/ACS/Cover/Analytical Chemistry/2021_37.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2021_37.png,clip,2021_37.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2016_5.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2016_5.png,vith,2016_5.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2014_16.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2014_16.png,vitg,2014_16.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_2.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_2.png,groundtruth,2025_2.txt,test
The Journal of Physical Chemistry Letters,2025_1,Which of the following options best describe the cover story?,"This visualization highlights the integration of artificial intelligence (AI) in analyzing X-ray diffraction (XRD) patterns for advanced material characterization. The image depicts AI-assisted processing of diffraction data, where machine-learning models facilitate full atomic structure characterization from experimental observations.",A,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_1.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2022_30.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2022_30.png,vitg,2022_30.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_43.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_43.png,vith,2021_43.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2011_3.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2011_3.png,clip,2011_3.txt,train
Evidence-Based Dentistry,25_3,Which of the following options best describe the cover story?,"In this issue:
This issue evaluates the evidence of effectiveness of some of the major dental public health initiatives and policy decisions. It also explores whether new approaches to prevention and treatment might prove effective against the most common dental diseases.
Cover illustration by Gary Neill",A,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_3.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_3.png,groundtruth,25_3.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_3.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_3.png,vitg,24_3.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,clip,24_4.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,ave_2,25_4.txt,test
Nature Biomedical Engineering,8_2,Which of the following options best describe the cover story?,"Biomolecular condensates as intracellular drug reservoirs
This issue highlights histopathological biomarkers for predicting the tumour accumulation of nanomedicines, the profiling of protein–protein interactions to predict the efficacy of inhibitors of acute myeloid leukaemia, the intravenous injection of oxygen via polymeric microbubbles for the treatment of hypoxaemia, the structural optimization of ionizable lipids in nanoparticles to improve their delivery activity and biodegradability, the radiation-induced reduction of platinum prodrugs, exosome-loaded degradable polymeric microcapsules for the treatment of vitreoretinal diseases, antibody-displaying extracellular vesicles for cancer therapy, the controlled formation of biomolecular condensates as intracellular drug reservoirs, and how amine headgroups in ionizable lipids drive the immunogenicity of lipid nanoparticles.
The cover illustrates a method for forming biomolecular condensates that serve as drug reservoirs within cancer cells.
See Liang et al.
Image: Zhen Gu, Hongjun Li and Tingxizi Liang, Zhejiang University. Cover design: Alex Wing.",C,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_12.png,ave_1,4_12.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_12.png,clip,7_12.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_2.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_2.png,groundtruth,8_2.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,vith,7_4.txt,test
Nature Geoscience,17_3,Which of the following options best describe the cover story?,"Graphitic carbon cycling during mountain building
Coupled rhenium–osmium and uranium–lead dating suggest graphitic carbon was hydrothermally cycled through shear zones during late-stage orogenesis associated with Nuna supercontinent assembly. The photomicrograph shows a hydrothermal graphite–pyrite vein in a highly sheared, metasomatized metapelite host rock viewed under both reflected and transmitted light (image dimensions: 550 μm x 550 μm). Graphite stands out from the ground mass due to its brown colour, high reflectance, and platy crystal habit.
See Toma et al.
Image: Jonathan Toma. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/2_5.png,MAC_Bench/Nature/Cover/Nature Geoscience/2_5.png,vith,2_5.txt,MAC_Bench/Nature/Cover/Nature Geoscience/6_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_7.png,vitg,6_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_3.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_3.png,groundtruth,17_3.txt,MAC_Bench/Nature/Cover/Nature Geoscience/12_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/12_1.png,clip,12_1.txt,train
Chemical Research in Toxicology,2024_5,Which of the following options best describe the cover story?,"Mn(III) chloride (TDCPP) can be used as an abiotic CYP enzyme for the metabolic activation of genotoxic chemicals, such as cyclophosphamide, in in vitro cell-based bioassays as an animal-free alternative to rat liver microsomes or S9 fraction.",C,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_1.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_5.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2021_4.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2021_4.png,ave_2,2021_4.txt,train
Nature Food,6_1,Which of the following options best describe the cover story?,"Nature Food 
Since the publication of Nature Food’s  first issue in January 2020, food systems research has come a long way — and much remains to be done. We celebrate the journal’s anniversary with a Focus issue and a webinar series.
See Editorial
Image: Shawn Williams / Alamy Stock Photo. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/Nature Food/5_2.png,MAC_Bench/Nature/Cover/Nature Food/5_2.png,vitg,5_2.txt,MAC_Bench/Nature/Cover/Nature Food/6_1.png,MAC_Bench/Nature/Cover/Nature Food/6_1.png,groundtruth,6_1.txt,MAC_Bench/Nature/Cover/Nature Food/2_7.png,MAC_Bench/Nature/Cover/Nature Food/2_7.png,vith,2_7.txt,MAC_Bench/Nature/Cover/Nature Food/2_3.png,MAC_Bench/Nature/Cover/Nature Food/2_3.png,clip,2_3.txt,train
Accounts of Chemical Research,2024_14,Which of the following options best describe the cover story?,"In the past, glycan synthesis has been difficult, requiring multi-step manual operations and a highly skilled workforce (at the remote end). Through the time and space tunnel, a donor preactivation-based strategy has enabled glycan synthesis from oligosaccharides to polysaccharides and from manual to automated synthesis, reaching a new height (at the proximal end).",A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_14.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_4.png,ave_1,2020_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2017_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2017_9.png,clip,2017_9.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_3.png,ave_2,2020_3.txt,train
ACS Measurement Science Au,2022_3,Which of the following options best describe the cover story?,Seeing is not believing: The weak transient current signals of single-particle collisions we recorded are often distorted by amplifiers' filter and the noise. It seems like we “see” signals from the reflection in the water. The “ripples” and “waving shadow” mask our “believing” of the dynamic nature of individual entities.,C,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2021_1.png,ave_2,2021_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_3.png,groundtruth,2022_3.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,vitg,2022_1.txt,train
Industrial & Engineering Chemistry Research,2024_37,Which of the following options best describe the cover story?,"The high concentration of oxygen vacancies on Ni/CeO2-NS facilitates the activation of water and oxygen molecules during methanol oxidative steam reforming, leading to enhanced conversion of methanol to hydrogen.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,clip,2021_45.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_37.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_37.png,groundtruth,2024_37.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,vith,2024_36.txt,val
Med,5_6,Which of the following options best describe the cover story?,"On the cover: Chemotherapies are currently dosed based on a patient's height and weight,
using an equation from 1916 to estimate their body surface area. This method leads
to variability in pharmacokinetics, potentially causing increased toxicities and decreased
efficacy. Personalized dosing could improve the patient's experience by providing
a more accurate dose, reducing side effects and increasing drug efficacy. In this
issue of Med, DeRidder et al. develop a closed-loop automated drug infusion regulator (CLAUDIA) system to address
this challenge by ensuring the drug reaches the target concentration regardless of
other factors. This illustration depicts a positive treatment experience, with patients
walking unbothered by their personalized chemotherapy dose represented by colorful
IV bags floating like balloons. Recovery is gentler, and daily life is less impacted
by chemotherapy. Cover credit: Virginia E. Fulford.",B,MAC_Bench/Cell/Cover/Med/2_4.png,MAC_Bench/Cell/Cover/Med/2_4.png,clip,2_4.txt,MAC_Bench/Cell/Cover/Med/5_6.png,MAC_Bench/Cell/Cover/Med/5_6.png,groundtruth,5_6.txt,MAC_Bench/Cell/Cover/Med/6_1.png,MAC_Bench/Cell/Cover/Med/6_1.png,ave_3,6_1.txt,MAC_Bench/Cell/Cover/Med/3_1.png,MAC_Bench/Cell/Cover/Med/3_1.png,ave_2,3_1.txt,train
Trends in Cancer,10_6,Which of the following options best describe the cover story?,"As each cancer is associated with unique microbiomes, bacteria is
becoming an attractive tool in cancer diagnostics and therapeutics. Engineered live
bacterial therapeutics are being employed to detect cancer as well as being modified
to stimulate anti-tumor immunity. In this issue, Siguenza et al. review the latest in the
use of engineered bacterial therapeutics for detecting and treating colorectal cancer.
Cover designed by Thom Leach.",D,MAC_Bench/Cell/Cover/Trends in Cancer/10_3.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_3.png,vitg,10_3.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_4.png,vith,10_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/8_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/8_1.png,clip,8_1.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,groundtruth,10_6.txt,val
Nature Microbiology,9_3,Which of the following options best describe the cover story?,"RNA viruses of parasitic nematodes
The parasitic nematode Brugia malayi (blue) is the causative agent of human lymphatic filariasis. In this issue, Quek et al. show that parasitic nematodes harbour a diverse virome that is associated with seropositivity in vertebrate hosts. In the case of B. malayi, the RNA virus BMRV1 (red) is distributed throughout the reproductive tissues, whereas the bacterial endosymbiont, Wolbachia (green), is abundant within the nematode’s chord cells.
See Quek et al.
Image: Shannon Quek. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Microbiology/1_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/1_2.png,vith,1_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_3.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_3.png,groundtruth,9_3.txt,MAC_Bench/Nature/Cover/Nature Microbiology/5_3.png,MAC_Bench/Nature/Cover/Nature Microbiology/5_3.png,vitg,5_3.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_9.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_9.png,clip,9_9.txt,train
ACS Sustainable Resource Management,2024_1,Which of the following options best describe the cover story?,"The proposed oil spill remediation technology, using a reusable superhydrophobic porous material derived from waste, can effectively remove oil from marine and coastal ecosystems. It minimizes harm to marine life, birds, and vegetation, offering a sustainable and eco-friendly solution for environmental cleanup.",B,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_1.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,vitg,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,ave_2,2025_2.txt,val
ACS Applied Energy Materials,2025_1,Which of the following options best describe the cover story?,"Understanding the growth mechanism of Li dendrites near pits is essential for improving battery performance, contributing to greater safety and efficiency.",D,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2020_11.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2020_11.png,clip,2020_11.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2019_7.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2019_7.png,vith,2019_7.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2018_2.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2018_2.png,vitg,2018_2.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2025_1.png,groundtruth,2025_1.txt,test
Industrial & Engineering Chemistry Research,2024_27,Which of the following options best describe the cover story?,A visible light photocatalyst-triggered Click reaction.,B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_9.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_9.png,vith,2023_9.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_27.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_27.png,groundtruth,2024_27.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_32.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_32.png,clip,2020_32.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_40.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_40.png,vitg,2022_40.txt,test
NATURE ENERGY,9_4,Which of the following options best describe the cover story?,"Entangled materials
Molecules with a non-fused ring structure are relatively cheap electron acceptor materials for organic solar cells. Yet, these molecules have poor crystallinity and do not blend well with electron donor materials. Zeng et al. use a binary solvent system to address these issues and demonstrate devices with over 19% power conversion efficiency.
See Zeng et al.
Cover Design: Thomas Phillips. Image: Lei Zhu and Feng Liu, Shanghai Jiao Tong University.",B,MAC_Bench/Nature/Cover/NATURE ENERGY/2_2.png,MAC_Bench/Nature/Cover/NATURE ENERGY/2_2.png,vitg,2_2.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_4.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_4.png,groundtruth,9_4.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/2_9.png,MAC_Bench/Nature/Cover/NATURE ENERGY/2_9.png,clip,2_9.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/1_11.png,MAC_Bench/Nature/Cover/NATURE ENERGY/1_11.png,vith,1_11.txt,train
ACS Chemical Neuroscience,2024_22,Which of the following options best describe the cover story?,"Unraveling the interplay between dopamine, carbon monoxide, and heme oxygenase: suggesting an axis that likely plays important roles in neuromodulation and cognition.",C,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_14.png,ave_1,2024_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_13.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_13.png,clip,2022_13.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_22.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_18.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_18.png,ave_2,2020_18.txt,test
Journal of Proteome Research,2025_3,Which of the following options best describe the cover story?,Proteomic analysis of human urinary exosome was successfully achieved with chemical affinity enrichment toward the phosphatidylserine exposure on the exosomal surface by molecular imprinting. View the article.,C,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_3.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_3.png,vitg,2024_3.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_8.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_8.png,vith,2024_8.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2025_3.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2017_2.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2017_2.png,clip,2017_2.txt,train
ACS Chemical Biology,2024_5,Which of the following options best describe the cover story?,The cover art illustrates the contribution of the non-covalent scaffold and the reactive warhead on the target engagement of covalent inhibitors as exemplified by covalent KRas G12C inhibitors. The background shows their target KRas G12C in a cellular environment approached by inhibitors representing different scaffold–warhead combinations.,A,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_5.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,ave_3,2019_9.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2023_10.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2023_10.png,vitg,2023_10.txt,train
Caner Cell,43_2,Which of the following options best describe the cover story?,"On the cover: The cover illustrates how glioblastoma (GBM) aligns its growth with
the brain's daily rhythms. Inspired by artist Sophie Taeuber-Arp and designed by Dr.
Olivia Walch, this visual highlights the daytime tumor growth driven by the circadian
surge in glucocorticoids (green dots). Gonzalez-Aponte et al. discover that blocking circadian regulation of glucocorticoid receptor signaling
slows GBM proliferation in both mouse and human GBM models. Targeting circadian mechanisms
to combat GBM holds great promise and has significant implications for understanding
how the circadian system may influence cancer progression, both within the brain and
beyond.",D,MAC_Bench/Cell/Cover/Caner Cell/28_4.png,MAC_Bench/Cell/Cover/Caner Cell/28_4.png,vith,28_4.txt,MAC_Bench/Cell/Cover/Caner Cell/26_5.png,MAC_Bench/Cell/Cover/Caner Cell/26_5.png,clip,26_5.txt,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,ave_2,33_2.txt,MAC_Bench/Cell/Cover/Caner Cell/43_2.png,MAC_Bench/Cell/Cover/Caner Cell/43_2.png,groundtruth,43_2.txt,train
Cancer Cell,42_7,Which of the following options best describe the cover story?,"On the cover: Liu et al. reveal the evolutionary dynamics and tumor-immune interplay in acral melanoma (AM).
The cover metaphorically represents the progression from AM in situ (AMis) to invasive AM (iAM). AMis tumors (grapes near vines) are homogeneous (green),
and iAM close to them are also green, indicating monoclonal dissemination. During
vertical invasion, some grapes change in shape and color, representing increased heterogeneity.
These abnormal tumors (purple grapes) are more invasive, and APOE+CD163+ macrophages
(birds) are attracted to promote tumor invasion. Image credit: Hengkang Liu and Ruidong
Xue.",B,MAC_Bench/Cell/Cover/Cancer Cell/34_1.png,MAC_Bench/Cell/Cover/Cancer Cell/34_1.png,vith,34_1.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_7.png,MAC_Bench/Cell/Cover/Cancer Cell/42_7.png,groundtruth,42_7.txt,MAC_Bench/Cell/Cover/Cancer Cell/19_3.png,MAC_Bench/Cell/Cover/Cancer Cell/19_3.png,vitg,19_3.txt,MAC_Bench/Cell/Cover/Cancer Cell/33_2.png,MAC_Bench/Cell/Cover/Cancer Cell/33_2.png,clip,33_2.txt,test
The Journal of Physical Chemistry Letters,2025_2,Which of the following options best describe the cover story?,"Aggregation leads to a considerable reduction in the medicinal effectiveness of drugs. This study investigates how structurally similar polyphenolic compounds self-aggregate, rendering them ineffective against cancer. Notably, due to dissimilarities in their backbone, the co-assembly prevents them from constructing a supramolecular architecture and disintegrates under physiological conditions, ultimately enhancing their effectiveness against cancer cells.",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_15.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_15.png,clip,2021_15.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_2.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_13.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_13.png,ave_2,2021_13.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2023_7.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2023_7.png,vitg,2023_7.txt,train
NATURE REVIEWS IMMUNOLOGY,24_5,Which of the following options best describe the cover story?,"Emergency myelopoiesis, inspired by the Review on p596.
Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_8.png,vith,14_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_2.png,clip,23_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_4.png,vitg,24_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_5.png,groundtruth,24_5.txt,val
NATURE REVIEWS DRUG DISCOVERY,23_4,Which of the following options best describe the cover story?,"Targeting chromatin remodellers, inspired by the Review on p661.
Cover design: S. Harris",D,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_1.png,clip,22_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_7.png,vith,21_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_5.png,vitg,20_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,groundtruth,23_4.txt,train
Journal of the American Chemical Society,2025_2,Which of the following options best describe the cover story?,"The cover art shows the top-down transformation of S-poisoned Pd nanoparticles to form high-performance Pd single atom sites, which represents a novel way to recycle wasted catalysts.",C,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_34.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_34.png,vith,2009_34.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_38.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_38.png,vitg,2024_38.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2025_2.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_48.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_48.png,clip,2016_48.txt,train
Biophysical Reports,4_1,Which of the following options best describe the cover story?,"On the cover: We used a pressure vessel model to investigate the relationship between
virus shape and critical stress and found that filament formation is a way of increasing
individual virus volume without particle rupture. DOI: 10.1016/j.bpr.2024.100181.",D,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,clip,4_3.txt,MAC_Bench/Cell/Cover/Biophysical Reports/1_1.png,MAC_Bench/Cell/Cover/Biophysical Reports/1_1.png,vitg,1_1.txt,MAC_Bench/Cell/Cover/Biophysical Reports/2_2.png,MAC_Bench/Cell/Cover/Biophysical Reports/2_2.png,vith,2_2.txt,MAC_Bench/Cell/Cover/Biophysical Reports/4_1.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_1.png,groundtruth,4_1.txt,train
NATURE MEDICINE,30_3,Which of the following options best describe the cover story?,"Unidirectional risk effects of clonal hematopoiesis on atherosclerosis
In this issue, Fuster and colleagues find that clonal hematopoiesis confers an increased risk of atherosclerosis. The cover highlights the finding that atherosclerosis, in turn, does not affect the risk of clonal hematopoiesis, indicative of a unidirectional effect.
See Fuster et al.
Image: Rosa Moro, Centro Nacional de Investigaciones Cardiovasculares. Cover design: Marina Corral Spence",C,MAC_Bench/Nature/Cover/NATURE MEDICINE/11_1.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/11_1.png,vith,11_1.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/15_8.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/15_8.png,vitg,15_8.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_3.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_3.png,groundtruth,30_3.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/23_7.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/23_7.png,clip,23_7.txt,train
NATURE IMMUNOLOGY,25_5,Which of the following options best describe the cover story?,"Classifying NK cells
Single-cell technologies have provided a complex understanding of natural killer (NK) cells that has led to variations in nomenclature and inconsistencies across the scientific literature. Here, Vivier and colleagues used these technologies to dissect the heterogeneity of NK cells, identifying three prominent NK cell subsets in healthy human blood.
See Rebuffet et al.
Image: Eric Vivier, INSERM. Cover design: Emily Paul",A,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_5.png,groundtruth,25_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_9.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_9.png,vitg,11_9.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/20_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/20_5.png,vith,20_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_3.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_3.png,clip,10_3.txt,val
Acta Pharmacologica Sinica,45_11,Which of the following options best describe the cover story?,"Cover Credit: Schematic illustration of possible mechanisms contributing to curcumin against desipramine-induced apoptosis and insulin secretion impairment. Curcumin could inhibit the binding of AKAP150 to PP2B and the phosphorylation of synapsin 1 induced by desipramine, and suppress desipramine-induced insulin secretion impairment. Moreover, curcumin could inhibit desipramine-induced apoptosis through PI3K/AKT/FOXO1 signaling pathway. (DOI 10.1038/s41401-023-01176-6). See the article in pages 327–338",D,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_3.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_3.png,clip,44_3.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_6.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_6.png,vith,43_6.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_7.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_7.png,vitg,41_7.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_11.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_11.png,groundtruth,45_11.txt,train
NATURE BIOTECHNOLOGY,42_11,Which of the following options best describe the cover story?,"Focus on protein engineering
Artistic impression of the three data types key to machine learning for functional protein design: structure, sequence and labels. The structure of carbonic anhydrase is shown in front of a background composed of amino acid letters representing sequence data. The hue overlay represents a fitness landscape that experimentally acquired labels help to map.
See Notin et al.
Image: Nathan Rollins, Pascal Notin. Cover Design: Erin Dewalt.",B,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/40_2.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/40_2.png,vith,40_2.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_11.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_11.png,groundtruth,42_11.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_9.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_9.png,vitg,41_9.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/43_1.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/43_1.png,clip,43_1.txt,train
NATURE BIOTECHNOLOGY,42_8,Which of the following options best describe the cover story?,"Young human glial progenitors replace older counterparts
An illustration of transplanted human glial progenitor cells (red) killing resident human glia (pink) in the adult mouse brain. Vieira et al. show that transplanted young glial progenitors outcompete older or diseased glia, suggesting a therapeutic strategy for neurodegenerative and myelin diseases.
See Vieira et al.
Image: Nadia Alzoubi. Cover design: Erin Dewalt",C,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_6.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_6.png,vith,39_6.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/29_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/29_4.png,ave_2,29_4.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_8.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_8.png,groundtruth,42_8.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_12.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_12.png,clip,42_12.txt,train
Nature Reviews Neurology,20_11,Which of the following options best describe the cover story?,"Inflammasome scaffolds, inspired by the Review on p67.
Cover design: Philip Patenall",D,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_7.png,vitg,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_6.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_6.png,vith,19_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_4.png,clip,20_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_11.png,groundtruth,20_11.txt,train
ACS Photonics,2024_9,Which of the following options best describe the cover story?,"The image shows a glowing circle of dots on a black background. The dots are evenly spaced and become smaller as they move away from the center, creating a sense of movement and energy.",B,MAC_Bench/ACS/Cover/ACS Photonics/2016_6.png,MAC_Bench/ACS/Cover/ACS Photonics/2016_6.png,ave_2,2016_6.txt,MAC_Bench/ACS/Cover/ACS Photonics/2024_9.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Photonics/2017_10.png,MAC_Bench/ACS/Cover/ACS Photonics/2017_10.png,clip,2017_10.txt,MAC_Bench/ACS/Cover/ACS Photonics/2021_5.png,MAC_Bench/ACS/Cover/ACS Photonics/2021_5.png,vith,2021_5.txt,train
ACS Organic & Inorganic Au,2023_2,Which of the following options best describe the cover story?,"To form high-density metal/oxide interfacial active sites, we developed a catalyst preparation method based on hybrid clustering. An iridium-molybdenum",C,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,vith,2023_5.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_2.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_2.png,groundtruth,2023_2.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,ave_1,2023_6.txt,val
ACS Synthetic Biology,2024_7,Which of the following options best describe the cover story?,"mediated gene silencing in Chlamydomonas reinhardtii: a cross-sectional view of C. reinhardtii highlights the precise interaction between DNA strands and gold nanoparticles, facilitated by a targeted LED light source. The illustration depicts the subsequent accumulation of lipid droplets indicative of silenced gene expression within the cell.",A,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_7.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,vith,2015_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_6.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_6.png,vitg,2023_6.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2022_9.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2022_9.png,clip,2022_9.txt,train
ACS Applied Bio Materials,2024_10,Which of the following options best describe the cover story?,"The image shows electrohydraulic discharge plasma disinfecting pathogens in a field of green cruciferous vegetables under a clear blue sky, symbolizing sustainable agriculture. Oxygen and nitrogen molecule icons around the plasma indicate RONS production, with a healthy sprouting cabbage seedling to signify seed growth promotion.",B,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2018_4.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2018_4.png,vitg,2018_4.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_12.png,ave_1,2024_12.txt,val
ACS Agricultural Science & Technology,2024_3,Which of the following options best describe the cover story?,View the article.,D,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_4.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_4.png,vitg,2024_4.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_2.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2021_6.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2021_6.png,vith,2021_6.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_3.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_3.png,groundtruth,2024_3.txt,train
Industrial & Engineering Chemistry Research,2024_13,Which of the following options best describe the cover story?,"This article presents the efficient utilization of artificial intelligence models to reliably predict the core dielectric and electrochemical properties of organic compounds. The cover art highlights AI-assisted prediction of molecular properties based on atomic composition. This cover art was created with the assistance of artificial intelligence tools, including ChatGPT, Copilot, and DALL-E.",A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_13.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_13.png,groundtruth,2024_13.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_28.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_28.png,vith,2024_28.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_19.png,clip,2023_19.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_15.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_15.png,vitg,2023_15.txt,train
Nature Reviews Physics,7_2,Which of the following options best describe the cover story?,"The cover of this issue illustrates the nuclear landscape with exotic nuclei. See Ye.
Image: Yanlin Ye. Cover design: Susanne Harris.",C,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_1.png,clip,5_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/7_2.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/7_2.png,groundtruth,7_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,vith,4_11.txt,train
Nature Structural & Molecular Biology,31_10,Which of the following options best describe the cover story?,"Insights into mitochondrial DNA packaging
A study by Isaac et al. presents mtFiber-seq, a method that measures individual mitochondrial genome packaging at nucleotide resolution, providing insight into the architecture of mitochondrial DNA packaging.
See Isaac et al.
IMAGE CREDIT: © Leidy Churchman, Courtesy Matthew Marks Gallery. COVER DESIGN: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_1.png,vitg,25_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,clip,28_8.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_10.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_10.png,groundtruth,31_10.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_1.png,vith,26_1.txt,train
ACS Earth and Space Chemistry,2024_2,Which of the following options best describe the cover story?,Tl+ added to birnessite in low Tl+/Mn doses triggers laminar to tunneled structure transformation via Mn(IV) reduction by water oxidation from the laminar birnessite.,A,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_2.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_10.png,vitg,2023_10.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_8.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_11.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_11.png,ave_2,2024_11.txt,train
Precision Chemistry,2024_11,Which of the following options best describe the cover story?,This cover image shows that a phosphino-phenolate nickel catalyst affords ultra-high molecular weight polyethylene (UHMWPE) from ethylene polymerization. The cobbles on the beach implies the capability of this precipitation polymerization strategy to afford polymer products with good morphology control.,C,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_4.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_4.png,ave_1,2023_4.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_11.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,vitg,2025_1.txt,train
Acta Pharmacologica Sinica,45_7,Which of the following options best describe the cover story?,"Cover Credit: In this cover article, Zhou et al. constructed a novel mechanistic quantitative systems pharmacology model describing the underlying pathophysiological processes of HER2+BC, from ligand-receptor binding to downstream signaling and finally to tumor growth, while incorporating the distinct modalities and mechanisms of various state-of-the-art therapeutics. A large variety of in vitro and in vivo experimental data was used during model calibration and validation, achieving a quantitative and accurate description of cellular signaling, time-response, dose-response, and tumor growth kinetics. In a high-throughput manner, this multiscale QSP model platform enabled researchers to probe into the efficacy of different therapeutic strategies at the preclinical level, generate new hypothesis regarding best treatment combinations to overcome resistance, and suggested important directions for future translational drug research and model-informed drug development. Doi:10.1038/s41401-024-01232-9. See the article in pages 1287–1304",D,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_6.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_6.png,vith,45_6.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,vitg,45_9.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_10.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_10.png,clip,44_10.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_7.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_7.png,groundtruth,45_7.txt,train
ACS Macro Letters,2024_3,Which of the following options best describe the cover story?,"Immiscible linear polymers (yellow vs blue) with diblock ring polymers at the interface under large shear deformation. A diblock ring threaded by two linear polymers from opposite sides is highlighted, demonstrating an adhesion mechanism analogous to the hook-and-loop process in Velcro tapes.",A,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_3.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2017_12.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2017_12.png,vitg,2017_12.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2018_6.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2018_6.png,clip,2018_6.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2013_1.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2013_1.png,vith,2013_1.txt,train
Trends in Pharmacological Sciences,46_1,Which of the following options best describe the cover story?,"Recent studies have highlighted the complexity of platelet biology, revealing
their diverse roles beyond hemostasis. Pathological platelet activation is now recognized
as
a key contributor to thrombosis and inflammation, both of which are central to cardiovascular
disease (CVD). Emerging research emphasizes the considerable impact of demographic
factors—such as age, sex, race, and ethnicity—on CVD risk and responses to antiplatelet
therapies. In this issue, Jain, Tyagi and colleagues review the influence of genetic
and non-genetic
factors including age, sex, race, and ethnicity on platelet function and responses
to
antiplatelet therapies. They emphasize the pressing need for further research into
platelet
biology and cardiovascular outcomes across diverse populations and advocate for tailored
therapeutic approaches in CVD based on recent demographic findings. The cover image,
conceptualized and designed by Kanika Jain and Tarun Tyagi using BioRender, features
a
heart, representing cardiovascular health, and hands holding platelets and medications,
symbolizing the interplay between pathological platelet activation—associated with
thrombosis—and therapeutic strategies crucial for CVD management. The diverse
individuals illustrate the impact of demographic factors on CVD risk. Images of heart
and
hands are from Adobe Stock images.",B,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_3.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_3.png,vitg,42_3.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_1.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_1.png,groundtruth,46_1.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_2.png,clip,46_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_11.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_11.png,ave_3,40_11.txt,train
Nature Photonics,18_8,Which of the following options best describe the cover story?,"Implantable biophotonics
Artistic image of an implantable wireless optoelectronic probe for monitoring tissue oxygenation levels within the brain. The microscale implant integrates an LED with a photodetector and is coated with a phosphorescent film which is sensitive to oxygen.
See Cai et al.
Image: Xing Sheng at Tsinghua University. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Photonics/16_11.png,MAC_Bench/Nature/Cover/Nature Photonics/16_11.png,vitg,16_11.txt,MAC_Bench/Nature/Cover/Nature Photonics/11_9.png,MAC_Bench/Nature/Cover/Nature Photonics/11_9.png,clip,11_9.txt,MAC_Bench/Nature/Cover/Nature Photonics/13_9.png,MAC_Bench/Nature/Cover/Nature Photonics/13_9.png,vith,13_9.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_8.png,MAC_Bench/Nature/Cover/Nature Photonics/18_8.png,groundtruth,18_8.txt,train
NATURE REVIEWS IMMUNOLOGY,25_2,Which of the following options best describe the cover story?,"Antibody-dependent Enhancement, inspired by the Review on p6.
Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,vitg,18_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/25_2.png,groundtruth,25_2.txt,train
Nature Cities,1_1,Which of the following options best describe the cover story?,"Navigating the waters
Water may be unchanging, but the cities through which water flows are not. An I and the City by Lu considers how Suzhou has changed around the Xiangxi River and the value of conserving historic identities. All cities straddle a broader reality, navigating political waters that can be as turbulent as physical ones.
See Lu
Image: Kan wang/Moment/Getty. Cover design: Lauren Heslop",D,MAC_Bench/Nature/Cover/Nature Cities/1_9.png,MAC_Bench/Nature/Cover/Nature Cities/1_9.png,clip,1_9.txt,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,ave_3,1_5.txt,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,ave_2,1_11.txt,MAC_Bench/Nature/Cover/Nature Cities/1_1.png,MAC_Bench/Nature/Cover/Nature Cities/1_1.png,groundtruth,1_1.txt,train
Cell Reports,43_7,Which of the following options best describe the cover story?,"On the cover: Aedes aegypti mosquitos that have fed on adenosine triphosphate (ATP)
colored with food dyes. In this issue, Sakuma et al. identify fibrinopeptide A (FPA) as a meal-terminating signal that is produced in
the host's blood during coagulation and increases in the mosquito's body as blood
feeding proceeds. In the absence of FPA, mosquitoes will ingest greater volumes of
blood or ATP. Image credit: Chisako Sakuma.",D,MAC_Bench/Cell/Cover/Cell Reports/18_8.png,MAC_Bench/Cell/Cover/Cell Reports/18_8.png,clip,18_8.txt,MAC_Bench/Cell/Cover/Cell Reports/35_12.png,MAC_Bench/Cell/Cover/Cell Reports/35_12.png,vitg,35_12.txt,MAC_Bench/Cell/Cover/Cell Reports/7_4.png,MAC_Bench/Cell/Cover/Cell Reports/7_4.png,ave_1,7_4.txt,MAC_Bench/Cell/Cover/Cell Reports/43_7.png,MAC_Bench/Cell/Cover/Cell Reports/43_7.png,groundtruth,43_7.txt,train
innovation,5_5,Which of the following options best describe the cover story?,"On the cover: Over the past three decades of exploration, Helicobacter pylori has
emerged as the most significant bacterium in the understanding of gastric diseases:
In 1984, the connection between Helicobacter pylori and gastritis, as well as gastric
ulcers, was first confirmed in humans. In 1994, the World Health Organization classified
Helicobacter pylori as a Group I carcinogen for gastric cancer. And in 2005, Dr. Barry
Marshall and Dr. Robin Warren were awarded the Nobel Prize in Physiology or Medicine
for their pioneering research in the field of Helicobacter pylori. Currently, Professor
Shen Lin's team at Peking University Cancer Hospital, through a combination of large-scale
clinical analysis and advanced omics technologies, has revealed the significant impact
of Helicobacter pylori on the efficacy of immunotherapy for gastrointestinal tumors.
This research opens up new directions for both clinical and basic studies of Helicobacter
pylori.",C,MAC_Bench/Cell/Cover/innovation/5_4.png,MAC_Bench/Cell/Cover/innovation/5_4.png,clip,5_4.txt,MAC_Bench/Cell/Cover/innovation/1_2.png,MAC_Bench/Cell/Cover/innovation/1_2.png,ave_2,1_2.txt,MAC_Bench/Cell/Cover/innovation/5_5.png,MAC_Bench/Cell/Cover/innovation/5_5.png,groundtruth,5_5.txt,MAC_Bench/Cell/Cover/innovation/5_1.png,MAC_Bench/Cell/Cover/innovation/5_1.png,vith,5_1.txt,train
Chemical & Biomedical ImagingOpen Access,2024_3,Which of the following options best describe the cover story?,molecular fingerprint,D,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_2.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_2.png,ave_2,2025_2.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,clip,2024_11.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_3.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_3.png,groundtruth,2024_3.txt,train
Nature Sustainability,7_3,Which of the following options best describe the cover story?,"Ancient soil enrichment
Amazonian dark earth, rich soil resulting from ancient human land modification, has the potential to store substantial amounts of carbon, yet the number and size of Amazonian dark earth sites is unknown. Goldberg and colleagues develop a remote-sensing approach leveraging machine-learning classifiers to reveal its present extent.
See Goldberg et al.
Image: Bruno Moraes Puente Institute, (Nederland, CO, USA) and the Amazon Hopes Collective. Cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/Nature Sustainability/6_7.png,MAC_Bench/Nature/Cover/Nature Sustainability/6_7.png,ave_3,6_7.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_12.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_12.png,clip,7_12.txt,MAC_Bench/Nature/Cover/Nature Sustainability/5_8.png,MAC_Bench/Nature/Cover/Nature Sustainability/5_8.png,vitg,5_8.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_3.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_3.png,groundtruth,7_3.txt,train
Trends in Cognitive Sciences,28_12,Which of the following options best describe the cover story?,"Research on human navigation has largely been limited to Western
environments and participants, but anthropological accounts reveal diverse cultural
adaptations to navigation. In this issue of Trends in Cognitive Sciences, Pablo Fernandez-
Velasco and Hugo Spiers connect these anthropological studies with cognitive
science research, emphasizing the diverse, multimodal environmental cues used by
indigenous communities. They further show how environmental cues are integrated with
systematized knowledge, visualization techniques, and cognitive artifacts to produce
a
rich and varied array of navigation systems across different cultures. Cover image
from
Justin Lewis/GettyImages.",B,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_5.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_5.png,vitg,17_5.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_12.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_12.png,groundtruth,28_12.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/23_9.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/23_9.png,ave_1,23_9.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_4.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_4.png,clip,18_4.txt,test
Nature Protocols,19_3,Which of the following options best describe the cover story?,"Unveiling gut architecture using high-dimensional immunofluorescence
To visualize the niche of murine intestinal mononuclear phagocytes and their association with other immune and stromal cells, a ‘Swiss roll’ section of the distal portion of the small intestine was stained for CODEX-PhenoCycler multiplexed imaging. This method, in conjunction with the tissue-rolling technique, allows the gut architecture to be dissected at single-cell resolution. See Monasterio et al.
Image: David A. Bejarano & Andreas Schlitzer, LIMES Institute, University of Bonn. Cover design: S. Whitham.",A,MAC_Bench/Nature/Cover/Nature Protocols/19_3.png,MAC_Bench/Nature/Cover/Nature Protocols/19_3.png,groundtruth,19_3.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_7.png,MAC_Bench/Nature/Cover/Nature Protocols/15_7.png,vitg,15_7.txt,MAC_Bench/Nature/Cover/Nature Protocols/18_6.png,MAC_Bench/Nature/Cover/Nature Protocols/18_6.png,ave_2,18_6.txt,MAC_Bench/Nature/Cover/Nature Protocols/14_12.png,MAC_Bench/Nature/Cover/Nature Protocols/14_12.png,clip,14_12.txt,train
Nature Reviews Electrical Engineering,1_12,Which of the following options best describe the cover story?,"Welcome to the first issue of Nature Reviews Electrical Engineering, a new Nature Reviews journal covering all areas of electrical engineering from electronics and photonics to robotics, telecommunications, energy and signal processing, with a particular focus on applied and industrial research.
Cover design: Sam Whitham",A,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_12.png,groundtruth,1_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,ave_2,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,ave_3,1_5.txt,train
Nature Reviews Physics,7_1,Which of the following options best describe the cover story?,"The cover of this issue illustrates the nuclear landscape with exotic nuclei. See Ye.
Image: Yanlin Ye. Cover design: Susanne Harris.",B,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/7_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/7_1.png,groundtruth,7_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_1.png,clip,5_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,vith,4_11.txt,test
Cell Metabolism,36_6,Which of the following options best describe the cover story?,"On the cover: This month we are celebrating Cell’s 50th anniversary by focusing on the exciting metabolic research that Cell Press
publishes across its titles. This month’s covers of Cell Metabolism, Cell, and Trends in Endocrinology & Metabolism, when put side-by-side, form a single image, reflective of the variety of topics
on metabolic research that you will find across the three journals and the connections
between them. Our cover reflects some of the contents of this issue, spanning from
review articles covering human cardiac metabolism (Bornstein et al.) and metabolic reprogramming in liver fibrosis (Horn and Tacke) to clinical studies on using thermal face imaging to predict aging and disease (Yu, Zhou, Mao et al.). Artwork credit: Sonhita Chakraborty.",D,MAC_Bench/Cell/Cover/Cell Metabolism/28_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/28_2.png,vith,28_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/34_11.png,MAC_Bench/Cell/Cover/Cell Metabolism/34_11.png,vitg,34_11.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png,clip,36_10.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_6.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_6.png,groundtruth,36_6.txt,train
Nature Machine Intelligence,6_2,Which of the following options best describe the cover story?,"Accelerating micromagnetic simulation with deep learning
Simulation has a crucial role in micromagnetic research. Traditional numerical methods face high computational demands, primarily due to long-range interactions. By leveraging the learning capabilities of a U-shaped neural network, computational complexity can be reduced from O(Nlog(N)) to O(N), facilitating scalable simulations for large sample sizes. The image depicts the simulated topological structure in a magnetic sample.
See Cai et al.
Image: Dong Wang, Tsinghua University. Cover design: Vanitha Selvarajan",A,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_2.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_2.png,groundtruth,6_2.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_8.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_8.png,vith,6_8.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/7_1.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/7_1.png,clip,7_1.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_1.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_1.png,vitg,2_1.txt,train
Science Translational Medicine,17_780,Which of the following options best describe the cover story?,"ONLINE COVER Against All Odds. The cover image shows an engineered HIV immunogen, 10.17GS (red and orange) in complex with an inferred unmutated common ancestor of the broadly neutralizing anti-HIV antibody, DH270 (gray and white). Glycans are shown in tan. HIV vaccines are designed to elicit broadly neutralizing antibodies. However, development of these antibodies requires accumulation of rare somatic mutations. Here, Swanson et al. engineered 10.17GS to specifically elicit these unlikely, but essential mutations, finding that it did so in three humanized immunoglobulin mouse models. This immunogen, and others like it, may increase the odds of a successful HIV vaccine. Credit: Swanson et alMAC_Bench/Science Translational Medicine",A,MAC_Bench/Science/Cover/Science Translational Medicine/17_780.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_780.png,groundtruth,17_780.txt,MAC_Bench/Science/Cover/Science Translational Medicine/5_194.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_194.png,vitg,5_194.txt,MAC_Bench/Science/Cover/Science Translational Medicine/13_585.png,MAC_Bench/Science/Cover/Science Translational Medicine/13_585.png,vith,13_585.txt,MAC_Bench/Science/Cover/Science Translational Medicine/2_35.png,MAC_Bench/Science/Cover/Science Translational Medicine/2_35.png,clip,2_35.txt,train
Nature Reviews Earth & Environment,6_1,Which of the following options best describe the cover story?,"Understanding of the Sumatran subduction zone and its hazards has increased since the 2004 Indian Ocean earthquake and tsunami. This Review commemorates the 20th anniversary of this event by outlining these insights and how they can inform future strategies to improve tsunami preparedness.
Jon Bower / Alamy Stock Photo. Cover design: Carl Conway.",A,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/6_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/6_1.png,groundtruth,6_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_4.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_4.png,vith,3_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_12.png,clip,2_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_12.png,vitg,4_12.txt,train
ACS Nano,2025_5,Which of the following options best describe the cover story?,"This image depicts ""fuzzy"" silicon-shelled nanocapsules with a heterogeneous size distribution being ""weighed"" by charge detection mass spectrometry (CDMS), a technique capable of individual particle mass measurements. This image was generated using iterative prompts to openart.ai.",D,MAC_Bench/ACS/Cover/ACS Nano/2025_4.png,MAC_Bench/ACS/Cover/ACS Nano/2025_4.png,clip,2025_4.txt,MAC_Bench/ACS/Cover/ACS Nano/2024_36.png,MAC_Bench/ACS/Cover/ACS Nano/2024_36.png,vitg,2024_36.txt,MAC_Bench/ACS/Cover/ACS Nano/2024_41.png,MAC_Bench/ACS/Cover/ACS Nano/2024_41.png,ave_1,2024_41.txt,MAC_Bench/ACS/Cover/ACS Nano/2025_5.png,MAC_Bench/ACS/Cover/ACS Nano/2025_5.png,groundtruth,2025_5.txt,test
Nature Reviews Electrical Engineering,1_9,Which of the following options best describe the cover story?,"Drawing inspiration from diverse energy processes in nature presents the opportunity to achieve efficient energy harvesting from water, sunlight, heat, and their hybrids through interfacial engineering. The cover image illustrates structural design for sunlight harvesting inspired by butterfly wing textures. See Wang et al.
Cover design: Sam Whitham",B,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,groundtruth,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_11.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_11.png,vith,1_11.txt,val
Nature Reviews Physics,6_3,Which of the following options best describe the cover story?,"The cover of this issue is based on the CERN accelerator complex. See the Editorial.
Image: S.Harris/Springer Nature Limited.",B,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_9.png,vith,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_3.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_3.png,groundtruth,6_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_9.png,clip,4_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_8.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_8.png,vitg,5_8.txt,train
One Earth,7_10,Which of the following options best describe the cover story?,"On the cover: Clean water is vital to the health of our planet, yet increasing anthropogenic
pressures threaten this precious resource. Here, the graceful swirls of an algae bloom
reveal a water system imperiled by agricultural runoff, with consequences for biodiversity
and human health. Anton Petrus for Getty Images.",D,MAC_Bench/Cell/Cover/One Earth/2_4.png,MAC_Bench/Cell/Cover/One Earth/2_4.png,vitg,2_4.txt,MAC_Bench/Cell/Cover/One Earth/2_6.png,MAC_Bench/Cell/Cover/One Earth/2_6.png,ave_3,2_6.txt,MAC_Bench/Cell/Cover/One Earth/8_1.png,MAC_Bench/Cell/Cover/One Earth/8_1.png,clip,8_1.txt,MAC_Bench/Cell/Cover/One Earth/7_10.png,MAC_Bench/Cell/Cover/One Earth/7_10.png,groundtruth,7_10.txt,val
Science Signaling,2007_397,Which of the following options best describe the cover story?,COVER This week features a Perspective on the role of molecular scaffolds in mediating crosstalk between different classes of seven-transmembrane receptors. The image depicts β-arrestin (PDB 1jsy).,B,MAC_Bench/Science/Cover/Science Signaling/5_245.png,MAC_Bench/Science/Cover/Science Signaling/5_245.png,vitg,5_245.txt,MAC_Bench/Science/Cover/Science Signaling/2007_397.png,MAC_Bench/Science/Cover/Science Signaling/2007_397.png,groundtruth,2007_397.txt,MAC_Bench/Science/Cover/Science Signaling/2_63.png,MAC_Bench/Science/Cover/Science Signaling/2_63.png,clip,2_63.txt,MAC_Bench/Science/Cover/Science Signaling/2_54.png,MAC_Bench/Science/Cover/Science Signaling/2_54.png,vith,2_54.txt,train
Industrial & Engineering Chemistry Research,2024_1,Which of the following options best describe the cover story?,"The cover depicts an integrated methane dehydroaromatization modular process being transported to natural gas extraction sites across various geographical terrains, ranging from the Rocky Mountains to deserts. The network nodes on the left symbolize the use of computational tools to infer the optimality of the modular process.",D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_35.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_35.png,vith,2018_35.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,clip,2022_11.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_43.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_43.png,vitg,2023_43.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_1.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_1.png,groundtruth,2024_1.txt,train
BDJ In Practice,37_12,Which of the following options best describe the cover story?,"Volume 37 | Issue 1 | January
In this issue we forecast developments in four areas of dentistry, take a closer look at how a life coach is relevant to dentistry and delve into the detail of England's Long Term Workforce Plan
Cover illustration by Tim Marrs",A,MAC_Bench/Nature/Cover/BDJ In Practice/37_12.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_12.png,groundtruth,37_12.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,ave_1,36_1.txt,MAC_Bench/Nature/Cover/BDJ In Practice/33_12.png,MAC_Bench/Nature/Cover/BDJ In Practice/33_12.png,clip,33_12.txt,MAC_Bench/Nature/Cover/BDJ In Practice/32_9.png,MAC_Bench/Nature/Cover/BDJ In Practice/32_9.png,vith,32_9.txt,train
Accounts of Chemical Research,2024_21,Which of the following options best describe the cover story?,"Enzyme-free dynamic DNA reaction networks represent a prospective branch for constructing high-efficiency molecular sensing tools. In this Account, we focus on the multidimensional performance of advanced nucleic acid circuits and discuss how to employ them for achieving precise imaging and cell regulation in bioanalysis.",C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_4.png,clip,2020_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_16.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_16.png,vith,2021_16.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_21.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_21.png,groundtruth,2024_21.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_22.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_22.png,vitg,2021_22.txt,train
NATURE MATERIALS,23_9,Which of the following options best describe the cover story?,"Deep-blue OLEDs shine
Suppressed Dexter transfer is needed to achieve efficient and stable hyperfluorescence, but complex matrices must be involved. A molecular design strategy has been proposed where Dexter transfer can be substantially reduced by an encapsulated terminal emitter, leading to ‘matrix-free’ hyperfluorescence.
See Cho et al.
Image: Pierangelo Pirak, Pomona Pictures. Cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_6.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_6.png,vith,19_6.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_11.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_11.png,vitg,21_11.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_4.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_4.png,clip,20_4.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_9.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_9.png,groundtruth,23_9.txt,train
Nature Photonics,18_3,Which of the following options best describe the cover story?,"Fluorescence-lifetime image scanning microscopy
Integrating a single-photon avalanche detector (SPAD) array into a confocal laser scanning microscope yields a twofold increase in the localization accuracy for single-molecule localization microscopy. The cover shows an artistic impression of the SPAD array detector with microlenses, where the two disks/shaded Gaussians depict the emission of two different fluorescent molecules hitting the detector array.
See Radmacher et al.
Image: Alexey Chizhik. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,vith,18_4.txt,MAC_Bench/Nature/Cover/Nature Photonics/3_6.png,MAC_Bench/Nature/Cover/Nature Photonics/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_3.png,MAC_Bench/Nature/Cover/Nature Photonics/18_3.png,groundtruth,18_3.txt,MAC_Bench/Nature/Cover/Nature Photonics/5_6.png,MAC_Bench/Nature/Cover/Nature Photonics/5_6.png,vitg,5_6.txt,train
Nature Reviews Rheumatology,20_11,Which of the following options best describe the cover story?,"Inspired by the Review on p81.
Cover design: Steven Hall",A,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,groundtruth,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,vith,10_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_6,Which of the following options best describe the cover story?,"‘Somitogenesis and segment determination, from head to tail’, inspired by the Review on p517
Cover design: Vicky Summersby",A,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_6.png,groundtruth,25_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_1.png,clip,24_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/20_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/20_9.png,vitg,20_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_11.png,vith,23_11.txt,train
Nature Reviews Endocrinology,20_7,Which of the following options best describe the cover story?,"Exploring links between obesity and the kidney, inspired by the Review on p321.
Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_7.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_7.png,vitg,18_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/10_3.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/10_3.png,ave_2,10_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_7.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_7.png,groundtruth,20_7.txt,train
Developmental Cell,59_6,Which of the following options best describe the cover story?,"On the cover: This is a confocal image of 5-day-old etiolated hypocotyls of an Arabidopsis thaliana mutant (mus3) with large aggregations of endomembrane components and plant cell wall polysaccharides
(in cyan: labeled with a membrane-associated dye, FM4-64, that is internalized by
endocytosis). Here, the authors demonstrate that sidechain addition to xyloglucan
polysaccharides is required for efficient packaging and secretion of polysaccharides
to the plant cell wall. To learn more about how polysaccharide structure affects transport
to the plant cell wall, see Hoffmann and McFarlane. Image credit: Natalie Hoffmann.",C,MAC_Bench/Cell/Cover/Developmental Cell/29_3.png,MAC_Bench/Cell/Cover/Developmental Cell/29_3.png,vith,29_3.txt,MAC_Bench/Cell/Cover/Developmental Cell/58_18.png,MAC_Bench/Cell/Cover/Developmental Cell/58_18.png,vitg,58_18.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_6.png,MAC_Bench/Cell/Cover/Developmental Cell/59_6.png,groundtruth,59_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/51_2.png,MAC_Bench/Cell/Cover/Developmental Cell/51_2.png,clip,51_2.txt,train
Nature Reviews Materials,9_6,Which of the following options best describe the cover story?,"In this Focus Issue we explore new research directions in the field of moiré materials, including results from global and local probe studies, the use of interlayer hybridization for property tuning, potential commonalities with the physics underlying strongly correlated materials, and the recent discovery of the fractional quantum anomalous Hall effect. See the Editorial
Cover design: David Johnston. Cover image: Nuckolls, K.P., et al. Nature 620, 525–532 (2023).",A,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_6.png,groundtruth,9_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/1_8.png,clip,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_3.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_3.png,vitg,2_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/1_6.png,vith,1_6.txt,train
Nature Nanotechnology,20_1,Which of the following options best describe the cover story?,"Memristors for on-chip intelligence
The image on the cover shows the optoelectronic memristor cells to be fully integrated as a 128 × 8 multi-mode array for in-sensor computing applications.
See Heyi Huang et al.
Image: Heyi Huang, Tsinghua University. Cover design: Vanitha Selvarajan",A,MAC_Bench/Nature/Cover/Nature Nanotechnology/20_1.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/20_1.png,groundtruth,20_1.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/12_3.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/12_3.png,ave_2,12_3.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/7_11.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/7_11.png,vith,7_11.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/15_6.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/15_6.png,clip,15_6.txt,train
Science Signaling,2007_380,Which of the following options best describe the cover story?,"COVER This week features a Teaching Resource on molecular events involved in the activation of apoptosis by the death receptor Fas. The image depicts activation of caspase 8 at the activated death receptor and adaptor protein complex. [Image: Drew Berry, The Walter and Eliza Hall Institute of Medical Research, Victoria, Australia]",A,MAC_Bench/Science/Cover/Science Signaling/2007_380.png,MAC_Bench/Science/Cover/Science Signaling/2007_380.png,groundtruth,2007_380.txt,MAC_Bench/Science/Cover/Science Signaling/5_245.png,MAC_Bench/Science/Cover/Science Signaling/5_245.png,vith,5_245.txt,MAC_Bench/Science/Cover/Science Signaling/3_136.png,MAC_Bench/Science/Cover/Science Signaling/3_136.png,clip,3_136.txt,MAC_Bench/Science/Cover/Science Signaling/5_223.png,MAC_Bench/Science/Cover/Science Signaling/5_223.png,vitg,5_223.txt,train
Cell Host&Microbe,32_6,Which of the following options best describe the cover story?,"On the cover: Cutibacterium acnes (C. acnes) is the most abundant human skin microbiota, contributing to the skin homeostasis.
In this issue of Cell Host & Microbe, Yu et al. demonstrate genetic heterogeneity and functional diversity of C. acnes in normal skin, atopic dermatitis, and acne (represented by the dyeing clothes from
left to right). Sebaceous glands (represented by the plaids in the clothes) that are
expanded in acne while reduced in atopic dermatitis influence the composition and
function of C. acnes. Artwork by Qing Zhang.",C,MAC_Bench/Cell/Cover/Cell Host&Microbe/7_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/7_3.png,clip,7_3.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,vitg,30_3.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_6.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_6.png,groundtruth,32_6.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,vith,31_4.txt,val
Macromolecules,2025_1,Which of the following options best describe the cover story?,"The cover art illustrates the dehydrogenative polymerization of formamides and alcohols to polyurethanes, driven by activated Fe(II) or Ru(II) catalysts. Vibrant hydrogen bubble evolution highlights isocyanate formation via formamide dehydrogenation, with dynamic polymer chains representing the precision and flow of the polycondensation process, emphasizing innovation in catalytic polymer chemistry. Image credit: Dr. Johannes Richers/Dr. Benjamin Large (Jo Richers Studio).",D,MAC_Bench/ACS/Cover/Macromolecules/2013_22.png,MAC_Bench/ACS/Cover/Macromolecules/2013_22.png,clip,2013_22.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_16.png,MAC_Bench/ACS/Cover/Macromolecules/2010_16.png,vith,2010_16.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_13.png,MAC_Bench/ACS/Cover/Macromolecules/2012_13.png,vitg,2012_13.txt,MAC_Bench/ACS/Cover/Macromolecules/2025_1.png,MAC_Bench/ACS/Cover/Macromolecules/2025_1.png,groundtruth,2025_1.txt,train
ACS Applied Polymer Materials,2024_19,Which of the following options best describe the cover story?,"Amorphous e-TiO2 nanoparticles, designed for large-scale production, with strong UV absorption but low photocatalytic activity, demonstrate superior UV resistance enhancement in a nanocomposite with an unsaturated polyester resin. This UPR/e-TiO2 material stands out as a valuable resin, particularly suitable for crafting a long-lasting outdoor usable artificial quartz stone with minimal color alteration.",D,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_7.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_7.png,vith,2023_7.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_4.png,vitg,2023_4.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_19.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_19.png,groundtruth,2024_19.txt,train
Chemistry of Materials,2025_1,Which of the following options best describe the cover story?,"A new cluster compound of RuSn6In6O16 crystallizes as orange crystals with Ru2+ and Sn2+ in the RuSn6 cluster, while the oxide layer is occupied by In3+. Despite the orange color of the crystals, the compound exhibits blue emission with a significant blue shift from its expected orange fluorescence.",D,MAC_Bench/ACS/Cover/Chemistry of Materials/2013_22.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2013_22.png,ave_1,2013_22.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2012_15.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2012_15.png,clip,2012_15.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2017_20.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2017_20.png,vitg,2017_20.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2025_1.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2025_1.png,groundtruth,2025_1.txt,train
Nature Electronics,7_9,Which of the following options best describe the cover story?,"Two in one with three terminals
A three-terminal gallium nitride (GaN)-based p‒n diode can operate as a light emitter or a detector. The scanning electron microscopy image on the cover highlights the structure of the three-terminal diode, which functions as a tunable light-emitting diode with a built-in bias tee circuit and a detector with a reconfigurable optoelectronic logic function.
See Memon et al.
Image: Haiding Sun & Muhammad Hunain Memon, University of Science and Technology of China. Cover design: Lauren Heslop.",C,MAC_Bench/Nature/Cover/Nature Electronics/1_7.png,MAC_Bench/Nature/Cover/Nature Electronics/1_7.png,ave_1,1_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/4_7.png,MAC_Bench/Nature/Cover/Nature Electronics/4_7.png,vitg,4_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_9.png,MAC_Bench/Nature/Cover/Nature Electronics/7_9.png,groundtruth,7_9.txt,MAC_Bench/Nature/Cover/Nature Electronics/2_6.png,MAC_Bench/Nature/Cover/Nature Electronics/2_6.png,clip,2_6.txt,train
Industrial & Engineering Chemistry Research,2024_39,Which of the following options best describe the cover story?,"I&ECR celebrates the illustrious career of Prof. Muthanna H. Al-Dahhan! In honor of his groundbreaking research and dedication to engineering education, we present this virtual special issue dedicated to his achievements. From pioneering multiphase reaction engineering to advancing clean energy production and sustainability, Prof. Al-Dahhan's contributions have shaped the field.",A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_39.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_39.png,groundtruth,2024_39.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_41.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_41.png,vitg,2024_41.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_4.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_4.png,vith,2021_4.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_22.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_22.png,clip,2020_22.txt,val
Nature Machine Intelligence,6_10,Which of the following options best describe the cover story?,"Learning phenotypes from cardiac geometry
Understanding the genetic factors that underlie the normal variation in cardiac shape is of great interest. In this work, Bonazzola et al. apply unsupervised geometric deep learning to phenotype the left ventricle by using an MRI-derived three-dimensional mesh representation (as depicted on the cover). The authors show that this approach boosts genetic discovery and provides deeper insights into the genetic underpinnings of cardiac morphology.
See Bonazzola et al.
Image: Rodrigo Bonazzola, University of Leeds. Cover design: Amie Fernandez",A,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_10.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_10.png,groundtruth,6_10.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/1_7.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_6.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_6.png,ave_3,2_6.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_1.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_1.png,clip,3_1.txt,train
Journal of the American Chemical Society,2024_30,Which of the following options best describe the cover story?,"Manipulating the cation composition of layered, P2-type Na2/3Ni1/3Mn2/3O2 with Li or Mn alters the interlayer cation ordering. The distinct interlayer arrangements of honeycomb-ordered transition metal layers significantly impact the Na+/vacancy ordering and diffusion. These insights provide design strategies for high-power, sustainable electrode materials to support renewable energy storage.  View the article.",A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_30.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_30.png,groundtruth,2024_30.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_48.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_48.png,clip,2017_48.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_25.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_25.png,ave_2,2019_25.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_47.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_47.png,vith,2011_47.txt,train
Nature Cities,1_8,Which of the following options best describe the cover story?,"Assessing building damage from war
Quantifying building damage during war is difficult but key for understanding its extent and for determining the rebuilding efforts required. This study uses a satellite imaging technique to focus on building damage in Syrian and Ukrainian cities.
See Hou et al.
Image: Naeblys / Alamy Stock Photo. Cover design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Cities/1_8.png,MAC_Bench/Nature/Cover/Nature Cities/1_8.png,groundtruth,1_8.txt,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,ave_2,1_7.txt,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,ave_3,1_2.txt,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,clip,1_3.txt,train
Cell Reports Physical Science,5_3,Which of the following options best describe the cover story?,"On the cover: Gu et al. report their observation of a sandwich-like ternary electron donor-acceptor complex
between electron-deficient aryl halides, a guanidine base, and tetrahydrofuran. The
cover image highlights the visible light absorption characteristics of this intriguing
donor-acceptor complex and its structural resemblance to a mouth-watering sandwich.
The strategy reported provides facile conditions for access to various alkyl aryl
ethers toward applications in fine chemical synthesis. The cover design was created
by Jiayi Gu.",B,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_10.png,vith,2_10.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,groundtruth,5_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,vitg,2_9.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_1.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_1.png,clip,3_1.txt,train
Nature Water,2_9,Which of the following options best describe the cover story?,"Agricultural trade and its impacts across population groups
The nexus of water, agriculture, and trade has global implications on multiple Sustainable Development Goals (SDGs), especially for the most vulnerable populations. The study by Weiyi Gu and colleagues finds striking trade-induced asymmetric water impacts across population groups. It thereby underscores that international agricultural trade eases water scarcity yet exacerbates inequity, disproportionately favouring more affluent populations. The authors urge future water and trade policies to strive for a better balance across multiple critical SDGs to achieve sustainable development for all.
See Gu et al.
Image: Weiyi Gu, Peking University. Cover design: Valentina Monaco.",D,MAC_Bench/Nature/Cover/Nature Water/2_2.png,MAC_Bench/Nature/Cover/Nature Water/2_2.png,ave_1,2_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Water/1_11.png,MAC_Bench/Nature/Cover/Nature Water/1_11.png,vitg,1_11.txt,MAC_Bench/Nature/Cover/Nature Water/2_9.png,MAC_Bench/Nature/Cover/Nature Water/2_9.png,groundtruth,2_9.txt,train
Industrial & Engineering Chemistry Research,2024_50,Which of the following options best describe the cover story?,electrochemical disc reactor,A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_50.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_50.png,groundtruth,2024_50.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_32.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_32.png,vith,2020_32.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_25.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_25.png,clip,2022_25.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_11.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_11.png,vitg,2023_11.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_9,Which of the following options best describe the cover story?,"The bispecific antibody landscape, inspired by the Review on p301.
Cover design: S. Harris",C,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_3.png,vith,19_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_12.png,vitg,22_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_9.png,groundtruth,23_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_10.png,clip,22_10.txt,train
ACS Chemical Neuroscience,2024_20,Which of the following options best describe the cover story?,"The artwork depicts how gut bacteria-derived SCFAs establish crosstalk with the brain and influence proteins and key neurotransmitters associated with treatment-resistant depression. SCFAs also positively modulate neuroplasticity, tryptophan metabolism, and inflammatory cascades in the brain that are involved in the management of anxiety and depression.",B,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_13.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_13.png,clip,2021_13.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_20.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_20.png,groundtruth,2024_20.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,vith,2023_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,vitg,2020_6.txt,train
Nature Reviews Clinical Oncology,21_5,Which of the following options best describe the cover story?,"Towards diversity in AI oncology applications, inspired by the Perspective on p628.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_5.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_5.png,vitg,20_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,vith,19_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_11.png,clip,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_5.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_5.png,groundtruth,21_5.txt,train
Journal of Medicinal Chemistry,2024_22,Which of the following options best describe the cover story?,"In our cover art, we incorporated elements from Chinese classical culture and symbolized the equipment for drug preparation with an alchemy furnace. The compound (S)-XY-05, which we have developed, effectively enters tumor cells and specifically inhibits PARP7. As a result, T cells are recruited and activated, leading to the destruction of tumor cells. To depict this process, we have represented T cells using arrows.",C,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_9.png,clip,2021_9.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2023_13.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2023_13.png,vitg,2023_13.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_22.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_18.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_18.png,vith,2024_18.txt,train
Nature Cities,1_10,Which of the following options best describe the cover story?,"Segregation shaping cities
Trends in segregation continue to shape cities worldwide. Examining different aspects, Elbers writes about demographic changes across US metro regions and Maloutas examines how vertical segregation within buildings affects inequality.
See Elbers & Maloutas
Image: C_Fernandes/iStock/Getty. Cover Design: Lauren Heslop.",A,MAC_Bench/Nature/Cover/Nature Cities/1_10.png,MAC_Bench/Nature/Cover/Nature Cities/1_10.png,groundtruth,1_10.txt,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,clip,1_3.txt,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,vith,1_11.txt,val
Science Signaling,2007_416,Which of the following options best describe the cover story?,"COVER This week features a Perspective about signals that specify axons and dendrites. The image shows that active Rit (a GTPase) is more abundant in the axon, where it contributes to the growth of this neuronal process. [Image: Christopher Bickel, AAAS]",B,MAC_Bench/Science/Cover/Science Signaling/2_59.png,MAC_Bench/Science/Cover/Science Signaling/2_59.png,vitg,2_59.txt,MAC_Bench/Science/Cover/Science Signaling/2007_416.png,MAC_Bench/Science/Cover/Science Signaling/2007_416.png,groundtruth,2007_416.txt,MAC_Bench/Science/Cover/Science Signaling/8_382.png,MAC_Bench/Science/Cover/Science Signaling/8_382.png,vith,8_382.txt,MAC_Bench/Science/Cover/Science Signaling/15_734.png,MAC_Bench/Science/Cover/Science Signaling/15_734.png,clip,15_734.txt,train
Cell Metabolism,36_3,Which of the following options best describe the cover story?,"On the cover: The conditionally essential amino acid serine is highly beneficial for
retinal and peripheral nerve health. Lim et al. find that circulating serine is the primary source of retinal serine levels, and
altering systemic serine influences visual function and retinal health. Here systemic
serine (glowing droplets) infuses retinal and peripheral nervous tissue to rescue
function as represented by the glowing flowers and root system. Illustration by Christina
Corbaci and Lars Hangartner.",D,MAC_Bench/Cell/Cover/Cell Metabolism/14_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/14_3.png,vith,14_3.txt,MAC_Bench/Cell/Cover/Cell Metabolism/17_6.png,MAC_Bench/Cell/Cover/Cell Metabolism/17_6.png,clip,17_6.txt,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,vitg,37_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_3.png,groundtruth,36_3.txt,train
Precision Chemistry,2024_6,Which of the following options best describe the cover story?,"The cover for the Special Issues ""Precision Chemistry for Two-Dimensional Materials (Part I)"" illustrates the precise growth of non-centrosymmetric two-dimensional single crystals. Humanoid models represent atoms A and B in the lattice, which are guided by the parallel steps. Cover art concept by Guoliang Cui and Xiaozhi Xu.",C,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,clip,2024_5.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_12.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_12.png,ave_3,2024_12.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_1.png,vitg,2024_1.txt,train
ACS Applied Engineering Materials,2024_9,Which of the following options best describe the cover story?,"elevated radiodensity, enabling real-time tracking of material development in living organisms through radioimaging. These hydrogels stand as a versatile and adjustable platform, allowing for the tunability of mechanical properties, swelling, and rates of biodegradation. Noteworthy for their cell-interactivity, biocompatibility, and biodegradability, these materials signify a leap forward in bioengineering innovation, specifically within the field of tissue engineering. View the article.",B,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,ave_3,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,ave_2,2024_3.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,clip,2024_12.txt,train
NATURE IMMUNOLOGY,25_4,Which of the following options best describe the cover story?,"Thymic involution and immune aging
Dudakov and colleagues identify changes in the mouse thymic stromal compartment associated with age and injury and find age-related thymic epithelial cells that form a non-functional microenvironment in the involuted thymus.
See Kousa et al.
Image: DrawImpacts. Cover design: Emily Paul",A,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_4.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_4.png,groundtruth,25_4.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/6_11.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/6_11.png,vith,6_11.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,clip,11_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/18_4.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/18_4.png,vitg,18_4.txt,train
NATURE REVIEWS CANCER,24_12,Which of the following options best describe the cover story?,"Chemotactic sirens, inspired by the Review on p28.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_12.png,clip,23_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_12.png,groundtruth,24_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/19_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/19_4.png,vith,19_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/18_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/18_1.png,vitg,18_1.txt,train
Trends in Biochemical Sciences,49_2,Which of the following options best describe the cover story?,"Enzymatic addition of phosphates at different positions on the inositol
ring, symbolized by a factory conveyor belt with robotic arms, generates a diverse
pool
of inositol phosphates (InsPs) in eukaryotic cells. InsPs can regulate protein function
by
several modes of action, represented by branches emerging from the central belt. On
pages 969–985, Kim et al explore the biochemical principles underlying the metabolism
of InsPs and their biological functions in mammals. Cover art by Jayraj Sen.",C,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_3.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_3.png,vith,49_3.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,vitg,47_14.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_2.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_2.png,groundtruth,49_2.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_7.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_7.png,clip,46_7.txt,train
innovation,6_2,Which of the following options best describe the cover story?,"On the cover: Wind, the movement of air, plays a vital role in influencing the Earth’s climate.
Moreover, wind energy is a form of renewable energy that harnesses the power of the
wind to generate electricity, serving as a cornerstone of the global energy transition.
As humanity increasingly turns to wind energy for a sustainable future, understanding
the factors shaping wind patterns has become more urgent than ever. While volcanic
eruptions are well known for their cooling effects and impacts on rainfall, their
influence on wind has largely gone unnoticed—until now. A study by Shen et al. reveals how the largest eruptions of the past millennium caused a significant, albeit
temporary, slowdown in global near-surface winds, particularly in subtropical regions.
Volcanic aerosols can disrupt wind energy systems, posing challenges to the resilience
of renewable energy. As the world races toward a carbon-neutral future, these findings
highlight an overlooked climate risk, urging us to consider the delicate effect from
natural forces on renewable energy systems.",C,MAC_Bench/Cell/Cover/innovation/3_1.png,MAC_Bench/Cell/Cover/innovation/3_1.png,ave_2,3_1.txt,MAC_Bench/Cell/Cover/innovation/4_1.png,MAC_Bench/Cell/Cover/innovation/4_1.png,ave_3,4_1.txt,MAC_Bench/Cell/Cover/innovation/6_2.png,MAC_Bench/Cell/Cover/innovation/6_2.png,groundtruth,6_2.txt,MAC_Bench/Cell/Cover/innovation/6_1.png,MAC_Bench/Cell/Cover/innovation/6_1.png,clip,6_1.txt,val
Cell Metabolism,36_11,Which of the following options best describe the cover story?,"On the cover: In this special issue, Ashcroft et al. review evidence detailing how exercise induces cardiometabolic health benefits across
multiple tissues. The cover centers around a running silhouette, which serves to highlight
the central importance of acute and chronic exercise interventions in the prevention
of metabolic disease. The exercising silhouette is set upon a background of symbols
and colors, which represent the adaptations that occur at a cellular level across
multiple tissues. Image by Mattias Karlén.",C,MAC_Bench/Cell/Cover/Cell Metabolism/22_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/22_3.png,vitg,22_3.txt,MAC_Bench/Cell/Cover/Cell Metabolism/24_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/24_5.png,vith,24_5.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_11.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_11.png,groundtruth,36_11.txt,MAC_Bench/Cell/Cover/Cell Metabolism/19_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/19_5.png,clip,19_5.txt,train
Immunity,57_1,Which of the following options best describe the cover story?,"On the cover: MacDonald et al. investigate the role of synovial tissue (ST) myeloid dendritic cells (DCs) in health,
active, and remission stages of rheumatoid arthritis (RA), identifying functional
features of distinct ST-DCs that provide insight into the roles of these cells in
immune tolerance and disease. The discovery process is illustrated as a team of archaeologists
uncovering the intricate patterns of a mosaic floor in an ancient Roman house (domus
romana). Diverse DC and T cell populations are depicted as colorful tiles forming
patterns in the ST (mosaic floor) atop the bloodstream (central heating system, hypocaustum)
from which DCs infiltrate the ST, determining the three conditions: health, disease,
and remission. Illustration by Art&Science: Dorotea Fracchiolla.",A,MAC_Bench/Cell/Cover/Immunity/57_1.png,MAC_Bench/Cell/Cover/Immunity/57_1.png,groundtruth,57_1.txt,MAC_Bench/Cell/Cover/Immunity/36_1.png,MAC_Bench/Cell/Cover/Immunity/36_1.png,vitg,36_1.txt,MAC_Bench/Cell/Cover/Immunity/33_4.png,MAC_Bench/Cell/Cover/Immunity/33_4.png,clip,33_4.txt,MAC_Bench/Cell/Cover/Immunity/32_5.png,MAC_Bench/Cell/Cover/Immunity/32_5.png,ave_1,32_5.txt,train
NATURE BIOTECHNOLOGY,42_6,Which of the following options best describe the cover story?,"Measuring organellar sodium ions
A DNA nanodevice measuring organellar sodium ion levels in lysosomes of living cells. Zou et al. developed RatiNa for imaging intracellular Na+ at single-organelle resolution.
See Zou et al.
Image: Junyi Zou and Bruna Di Giacomo. Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_5.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_5.png,vitg,41_5.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_6.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_6.png,groundtruth,42_6.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/33_5.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/33_5.png,vith,33_5.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/23_11.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/23_11.png,clip,23_11.txt,train
Molecular Cell,85_4,Which of the following options best describe the cover story?,"On the cover: RNA modifications decorate RNA molecules, changing their physico-chemical
properties. Ribosomal RNAs (rRNAs) are heavily modified, with more than 200 modified
sites annotated in human rRNAs. In this issue of Molecular Cell, Milenkovic et al. systematically survey the rRNA modification patterns in development, differentiation,
and disease, finding that they represent epitranscriptomic fingerprints of their cells
and tissues of origin. These fingerprints can be used to predict developmental stages,
tissues, cell types, and cancer from as few as 250 reads. Cover artwork by Queralt
Tolosa (https://www.queralttolosa.com).",C,MAC_Bench/Cell/Cover/Molecular Cell/54_4.png,MAC_Bench/Cell/Cover/Molecular Cell/54_4.png,vith,54_4.txt,MAC_Bench/Cell/Cover/Molecular Cell/43_1.png,MAC_Bench/Cell/Cover/Molecular Cell/43_1.png,clip,43_1.txt,MAC_Bench/Cell/Cover/Molecular Cell/85_4.png,MAC_Bench/Cell/Cover/Molecular Cell/85_4.png,groundtruth,85_4.txt,MAC_Bench/Cell/Cover/Molecular Cell/51_2.png,MAC_Bench/Cell/Cover/Molecular Cell/51_2.png,vitg,51_2.txt,train
ACS Omega,2025_2,Which of the following options best describe the cover story?,"Flavin-dependent tryptophan halogenases like AbeH show great potential as synthetic tools for regioselective green aryl halide production, despite suboptimal catalytic efficiency. Crystallography and ITC have determined that negative coupling between flavin and substrate binding limits turnover by preventing tryptophan from binding to AbeH as long as flavin remains bound.",C,MAC_Bench/ACS/Cover/ACS Omega/2024_29.png,MAC_Bench/ACS/Cover/ACS Omega/2024_29.png,vitg,2024_29.txt,MAC_Bench/ACS/Cover/ACS Omega/2019_18.png,MAC_Bench/ACS/Cover/ACS Omega/2019_18.png,vith,2019_18.txt,MAC_Bench/ACS/Cover/ACS Omega/2025_2.png,MAC_Bench/ACS/Cover/ACS Omega/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Omega/2021_17.png,MAC_Bench/ACS/Cover/ACS Omega/2021_17.png,clip,2021_17.txt,val
ACS Photonics,2024_10,Which of the following options best describe the cover story?,"The roadmap for optical metasurfaces highlights unique opportunities for the field when strong scientific achievements coincide with substantial industrial demand, driving metasurface research and technology development toward its future impact.",C,MAC_Bench/ACS/Cover/ACS Photonics/2024_5.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_5.png,vitg,2024_5.txt,MAC_Bench/ACS/Cover/ACS Photonics/2021_12.png,MAC_Bench/ACS/Cover/ACS Photonics/2021_12.png,vith,2021_12.txt,MAC_Bench/ACS/Cover/ACS Photonics/2024_10.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Photonics/2018_8.png,MAC_Bench/ACS/Cover/ACS Photonics/2018_8.png,clip,2018_8.txt,train
Evidence-Based Dentistry,25_4,Which of the following options best describe the cover story?,"In this issue:
This issue of Evidence Based Dentistry seeks to present readers and clinicians with widest possible spectrum of information about dentistry and oral health. It describes evidence from social and public health, oral medicine, and surgical and restorative research. The focus is , however, on the external influences on oral health
Cover illustration by Gary Neill",B,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_3.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_3.png,clip,24_3.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,groundtruth,25_4.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,vitg,24_4.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_1.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_1.png,ave_3,25_1.txt,train
Science Immunology,9_102,Which of the following options best describe the cover story?,"ONLINE COVER How Helminths Evade the Immune System. Approximately one-third of humans are infected by worm-like parasites called helminths, which have developed multiple strategies to evade immune-mediated destruction. Bohnacker et al. studied mice infected with the murine intestinal helminth Heligmosomoides polygyrus bakeri (Hpb) to define parasite-mediated mechanisms of immune evasion. They report that helminthic glutamate dehydrogenase (heGDH) targets macrophages by inducing production of prostaglandin E2 (PGE2) and other immunomodulatory molecules. heGDH also suppresses leukotriene synthesis, which prevents alternative macrophage and T helper 2 (TH2) cell activation. This is yet another strategy devised by helminths to suppress antiparasite immune responses and thereby facilitate the establishment of chronic infections. This month’s cover features an adult female Hpb in the center, flanked by adult Hpb males with their characteristic caudal bursae on the left and right sides, crescent-shaped Hpb larvae from various stages surrounding the adults, and Hpb eggs in the four corners of the image. Credit: A. Mastin/Science Immunology",B,MAC_Bench/Science/Cover/Science Immunology/8_79.png,MAC_Bench/Science/Cover/Science Immunology/8_79.png,clip,8_79.txt,MAC_Bench/Science/Cover/Science Immunology/9_102.png,MAC_Bench/Science/Cover/Science Immunology/9_102.png,groundtruth,9_102.txt,MAC_Bench/Science/Cover/Science Immunology/5_48.png,MAC_Bench/Science/Cover/Science Immunology/5_48.png,vitg,5_48.txt,MAC_Bench/Science/Cover/Science Immunology/5_46.png,MAC_Bench/Science/Cover/Science Immunology/5_46.png,vith,5_46.txt,train
Nature Reviews Materials,9_5,Which of the following options best describe the cover story?,"CO2 electroreduction aims to decarbonize by converting CO2 and clean energy into chemicals. To have an impact, this technology should be scaled up into the gigatonne conversion range, which involves challenges related to resource and material scalability bottlenecks. The cover shows an artistic representation of the implementation of CO2 electrolysis to scale and its materials needs. See Belsa B. et al.
Cover image: Francisco Pelayo García de Arquer. Cover design: David Johnston.",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,vitg,9_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_4.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_4.png,clip,8_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_11.png,ave_3,8_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_5.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_5.png,groundtruth,9_5.txt,train
Organic Letters,2025_7,Which of the following options best describe the cover story?,This cover art illustrates that when,A,MAC_Bench/ACS/Cover/Organic Letters/2025_7.png,MAC_Bench/ACS/Cover/Organic Letters/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/Organic Letters/2024_13.png,MAC_Bench/ACS/Cover/Organic Letters/2024_13.png,vitg,2024_13.txt,MAC_Bench/ACS/Cover/Organic Letters/2022_46.png,MAC_Bench/ACS/Cover/Organic Letters/2022_46.png,clip,2022_46.txt,MAC_Bench/ACS/Cover/Organic Letters/2024_2.png,MAC_Bench/ACS/Cover/Organic Letters/2024_2.png,vith,2024_2.txt,train
CHEMICAL REVIEWS,2025_3,Which of the following options best describe the cover story?,"Electronic nanochips offer electric fields that are able to precisely modulate molecular activities from molecular movements and physical properties to chemical reactions and optoelectronic functions. The utilization of electric fields to manipulate molecular behaviors on the nanoscale is a new research field that can inspire curiosity and lead to innovative discoveries of new quantum effects and new chemistry, improving our understanding of the molecular world.",D,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_3.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_3.png,ave_1,2019_3.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_4.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_4.png,ave_2,2016_4.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_10.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_10.png,clip,2019_10.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_3.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_3.png,groundtruth,2025_3.txt,train
NATURE REVIEWS CANCER,24_8,Which of the following options best describe the cover story?,"Fungi in focus, inspired by the Viewpoint on p295.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_11.png,vitg,23_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_8.png,groundtruth,24_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_2.png,clip,23_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_4.png,vith,13_4.txt,val
ACS Energy Letters,2024_11,Which of the following options best describe the cover story?,concomitantly formed back-surface electrical-field and reduced surface potential fluctuations reinforce the built-in electric-field and minimize the electron extraction barrier. This work represents a promising strategy to energy-level optimization at the heterojunction interface.,A,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_11.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2025_2.png,ave_1,2025_2.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2018_6.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2018_6.png,vitg,2018_6.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2023_11.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2023_11.png,clip,2023_11.txt,train
Journal of Proteome Research,2024_3,Which of the following options best describe the cover story?,A proteomic analysis of plasma samples using data-independent acquisition (DIA) methodology was conducted to shed light on the pathogenesis of infantile epileptic spasm syndrome (IESS).,A,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_3.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2021_2.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2021_2.png,ave_2,2021_2.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_4.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_4.png,vitg,2016_4.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2018_6.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2018_6.png,clip,2018_6.txt,train
ACS Applied Polymer Materials,2025_2,Which of the following options best describe the cover story?,This cover art illustrates the antibacterial schematic diagram of the versatile gelatin-PAAm-Ag NPs double network hydrogel coating on both the outer and lumen (inner) surfaces of disposable silicified latex urinary catheters (UCs). This study provides valuable insights and strategies for the development of novel antibacterial hydrogel coatings for UCs and other biomedical devices aimed at reducing catheter-associated urinary tract infections.,B,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_9.png,vith,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_4.png,clip,2023_4.txt,train
ACS Materials Au,2024_5,Which of the following options best describe the cover story?,This front cover represents the idea that science should be inclusive. We created a collage in which a face is composed and enriched by incorporating features of various women's faces worldwide. This work is part of the ACS-wide DEIR Cover Art program.,B,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,ave_3,2023_2.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2024_5.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_6.png,vith,2023_6.txt,train
ACS Materials Letters,2025_1,Which of the following options best describe the cover story?,A host–guest approach is developed for the induction of chiral luminescence in a series of achiral porphyrin nanostructures through their co-assembly with chiral gelators. Modulating specific interactions between the host and guest helped achieve intense chiral emission with desired handedness.,B,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_1.png,clip,2022_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2025_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_3.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_3.png,vith,2024_3.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_5.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_5.png,vitg,2023_5.txt,train
ACS Energy Letters,2024_9,Which of the following options best describe the cover story?,"In-detail experimental and theoretical analysis derived that crown ethers are impressive for surface passivation and a guardian layer against moisture owing to their unique acid-base passivation and hydrophobicity, and crown ethers with appropriate molecular design at the perovskite/electron transfer layer interface inhibit the nonradiative recombination and voltage losses in p-i-n perovskite solar cells.",A,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_9.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_6.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_6.png,clip,2021_6.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2017_2.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2017_2.png,vith,2017_2.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_8.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_8.png,ave_1,2021_8.txt,test
Cell Genomics,5_2,Which of the following options best describe the cover story?,"On the cover: The cover illustrates the dynamic process of bacterial immune adaptation
against bacterial viruses (phages) in different environments via a key mechanism of
acquiring CRISPR-Cas spacers, a study conducted by An-Ni Zhang et al. in this issue of Cell Genomics. The green section shows the rapid immunity update observed in controlled experimental
conditions, occurring on a timescale of hours. In contrast, the red section demonstrates
a much slower rate of CRISPR-Cas spacer acquisition in natural environments, such
as the human gut microbiome, where updates occur over several years. The findings
of this study further unravel the underlying mechanisms driving the continual arms
race between hosts and parasites in various organisms. Artist credit: An-Ni Zhang.",B,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,ave_2,4_12.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,groundtruth,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,ave_3,4_7.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_1.png,MAC_Bench/Cell/Cover/Cell Genomics/5_1.png,clip,5_1.txt,train
Cell Chemical Biology,32_1,Which of the following options best describe the cover story?,"On the cover: Sharma et al. describe the chemical interplay between the gut microbiota and host circadian physiology
via the epigenetic circuit. Members of the gut microbiota fine-tune host functions
(yellow bacterium and pink intestinal epithelial cells), synthesize host-sensed metabolites
(orange bacterium and orange-yellow receptor), interact with intestinal epithelium
and immune cells (blue, dark green, and light green bacterium and light-orange immune
cell), and can harm the host (purple bacterium). Cover art by Samskrathi Aravinda
Sharma.",A,MAC_Bench/Cell/Cover/Cell Chemical Biology/32_1.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/32_1.png,groundtruth,32_1.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/16_8.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/16_8.png,clip,16_8.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/17_6.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/17_6.png,vitg,17_6.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/23_6.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/23_6.png,vith,23_6.txt,train
Nature Electronics,7_11,Which of the following options best describe the cover story?,"3D resonators for spectral processors
Spectral processors for wireless communication can be created using acoustic resonators made from 3D silicon nano-fins with hafnia–zirconia ferroelectric gates wrapped around them. The scanning electron microscopy image on the cover shows an array of filters created by electrically coupling 3D resonators with different frequencies, with the different devices highlighted by different false colours.
See Hakim et al.
Image: Faysal Hakim, University of Florida. Cover design: Lauren Heslop.",A,MAC_Bench/Nature/Cover/Nature Electronics/7_11.png,MAC_Bench/Nature/Cover/Nature Electronics/7_11.png,groundtruth,7_11.txt,MAC_Bench/Nature/Cover/Nature Electronics/3_4.png,MAC_Bench/Nature/Cover/Nature Electronics/3_4.png,clip,3_4.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_8.png,MAC_Bench/Nature/Cover/Nature Electronics/7_8.png,vith,7_8.txt,MAC_Bench/Nature/Cover/Nature Electronics/2_12.png,MAC_Bench/Nature/Cover/Nature Electronics/2_12.png,vitg,2_12.txt,test
NATURE BIOTECHNOLOGY,42_2,Which of the following options best describe the cover story?,"CAR T cells eradicate solid tumors
An illustration of intact mitochondria (yellow) in IL-10-expressing CAR T cells. Zhao et al. show that expressing IL-10 in CAR T cells improves their mitochondrial function and therapeutic efficacy in multiple solid-tumor models.
See Zhao et al.
Image: Yiling Li, Li Tang, Yugang Guo. Cover design: Erin Dewalt",D,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_12.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_12.png,vitg,39_12.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_9.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_9.png,vith,41_9.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/21_6.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/21_6.png,clip,21_6.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_2.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_2.png,groundtruth,42_2.txt,train
Biomacromolecules,2024_3,Which of the following options best describe the cover story?,"Growth of HBV capsids from homodimers generates new contacts among charged headgroups in the dimer–dimer interface, yielding protein charge transfer spectra measurable in real-time. Photoinduced electron transfer is shown to occur from the HOMO of COO− in one glutamate (donor) to the LUMO of NH3+ in lysine or the polypeptide backbone (acceptor).",A,MAC_Bench/ACS/Cover/Biomacromolecules/2024_3.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_6.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_6.png,vith,2021_6.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2023_4.png,MAC_Bench/ACS/Cover/Biomacromolecules/2023_4.png,clip,2023_4.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2017_3.png,MAC_Bench/ACS/Cover/Biomacromolecules/2017_3.png,vitg,2017_3.txt,train
Science Signaling,2007_401,Which of the following options best describe the cover story?,COVER This week features a Review on PB1 domains. The image depicts the structures making up the p40phox and p67phox PB1 complex. [Image: PDB entry 1OEY],A,MAC_Bench/Science/Cover/Science Signaling/2007_401.png,MAC_Bench/Science/Cover/Science Signaling/2007_401.png,groundtruth,2007_401.txt,MAC_Bench/Science/Cover/Science Signaling/2007_414.png,MAC_Bench/Science/Cover/Science Signaling/2007_414.png,clip,2007_414.txt,MAC_Bench/Science/Cover/Science Signaling/5_250.png,MAC_Bench/Science/Cover/Science Signaling/5_250.png,vitg,5_250.txt,MAC_Bench/Science/Cover/Science Signaling/5_245.png,MAC_Bench/Science/Cover/Science Signaling/5_245.png,vith,5_245.txt,train
Nature Reviews Earth & Environment,5_4,Which of the following options best describe the cover story?,"Mine tailings are voluminous and often-toxic wastes, whose management is a global safety and sustainability challenge. This Review summarizes major tailings storage facility disasters and impacts, emphasizing the need for risk reduction approaches for management and policy.
Image credit: Agencia Brasil/Alamy Stock Photo. Cover design: Carl Conway.",A,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_4.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_4.png,groundtruth,5_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_12.png,ave_3,2_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_3.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_3.png,vith,2_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_12.png,clip,4_12.txt,train
Science Signaling,2007_383,Which of the following options best describe the cover story?,"COVER This week's Focus Issue, published to complement the Science Special Issue on Germ Cells, contains an Editorial Guide as well as one Perspective on the migration of primordial germ cells and elimination of those that fail to migrate and one on poppy rejection of self-incompatible pollen. The image depicts a pollen tube. [Image: Christopher Bickel, AAAS]",A,MAC_Bench/Science/Cover/Science Signaling/2007_383.png,MAC_Bench/Science/Cover/Science Signaling/2007_383.png,groundtruth,2007_383.txt,MAC_Bench/Science/Cover/Science Signaling/17_829.png,MAC_Bench/Science/Cover/Science Signaling/17_829.png,vitg,17_829.txt,MAC_Bench/Science/Cover/Science Signaling/16_797.png,MAC_Bench/Science/Cover/Science Signaling/16_797.png,clip,16_797.txt,MAC_Bench/Science/Cover/Science Signaling/8_366.png,MAC_Bench/Science/Cover/Science Signaling/8_366.png,vith,8_366.txt,train
Nature Reviews Clinical Oncology,21_6,Which of the following options best describe the cover story?,"Leveraging multispecific antibodies to treat patients with cancer, inspired by the Review on p539.
Cover design: Lara Crow",C,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_7.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_7.png,vith,18_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_6.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_6.png,groundtruth,21_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_7.png,vitg,19_7.txt,train
Nature Aging,4_8,Which of the following options best describe the cover story?,"The aging lipidome
In this issue, two studies comprehensively describe the lipidome during aging in mice. Janssens et al. report that bis(monoacylglycero)phosphate (BMP) accumulates during mouse aging, and that this lipid also accumulates in muscle in older humans and reduces upon a short bout of exercise. Tsugawa et al. profile the lipidome in 13 tissues and 4 ages of mice, taking into account sex and microbiome dependencies. Among many findings, they report that polyunsaturated fatty acid-containing BMP increases in various organs during aging. The cover shows a pocket watch being pushed by two older people. The numbers on the face of the clock are BMP molecules, which become larger in size to reflect their increased abundance with age. Pushing the clock denotes that BMP levels can be modified by exercise.
See Janssens et al. & Tsugawa et al.
Image: Joana C. Carvalho. Cover design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,groundtruth,4_8.txt,MAC_Bench/Nature/Cover/Nature Aging/1_11.png,MAC_Bench/Nature/Cover/Nature Aging/1_11.png,vith,1_11.txt,MAC_Bench/Nature/Cover/Nature Aging/4_4.png,MAC_Bench/Nature/Cover/Nature Aging/4_4.png,clip,4_4.txt,MAC_Bench/Nature/Cover/Nature Aging/2_12.png,MAC_Bench/Nature/Cover/Nature Aging/2_12.png,vitg,2_12.txt,train
Organic Letters,2025_6,Which of the following options best describe the cover story?,This cover art illustrates that when,D,MAC_Bench/ACS/Cover/Organic Letters/2024_2.png,MAC_Bench/ACS/Cover/Organic Letters/2024_2.png,vith,2024_2.txt,MAC_Bench/ACS/Cover/Organic Letters/2024_13.png,MAC_Bench/ACS/Cover/Organic Letters/2024_13.png,vitg,2024_13.txt,MAC_Bench/ACS/Cover/Organic Letters/2022_46.png,MAC_Bench/ACS/Cover/Organic Letters/2022_46.png,clip,2022_46.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_6.png,MAC_Bench/ACS/Cover/Organic Letters/2025_6.png,groundtruth,2025_6.txt,train
Accounts of Materials Research,2024_12,Which of the following options best describe the cover story?,"Integrating domain knowledge into artificial intelligence, this Account signifies a transformative shift in catalytic materials discovery toward a sustainable future. Cover designed by Tianyou Mou with help from Xue Han.",C,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_6.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_6.png,clip,2021_6.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_1.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_1.png,vitg,2021_1.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_12.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_9.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_9.png,vith,2021_9.txt,train
Biomacromolecules,2024_9,Which of the following options best describe the cover story?,"The combination of experimental techniques and computational simulations presents a powerful approach to study polymer vesicles at multiple scales, which enables us to explore the interplay between phenomena and mechanisms in the emerging field of polymersome-based drug delivery systems.",B,MAC_Bench/ACS/Cover/Biomacromolecules/2022_5.png,MAC_Bench/ACS/Cover/Biomacromolecules/2022_5.png,vith,2022_5.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_9.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2019_6.png,MAC_Bench/ACS/Cover/Biomacromolecules/2019_6.png,vitg,2019_6.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2019_4.png,MAC_Bench/ACS/Cover/Biomacromolecules/2019_4.png,clip,2019_4.txt,train
Nature Reviews Rheumatology,20_3,Which of the following options best describe the cover story?,"Inspired by the Review on p601.
Cover design: Steven Hall",B,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/17_1.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/17_1.png,vitg,17_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_3.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_3.png,groundtruth,20_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,vith,10_11.txt,train
Nature Reviews Rheumatology,20_5,Which of the following options best describe the cover story?,"Inspired by the Review on p459.
Cover design: Steven Hall",B,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_5.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_5.png,groundtruth,20_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,train
ACS Chemical Neuroscience,2024_3,Which of the following options best describe the cover story?,"The cover art features four pseudo-colored composite images of pERK-stained zebrafish larval brains, showcasing the effects of a vehicle and three behavior-modifying neuroactive isoflavones. Below, a mosaic time series depicts the animals' behavioral responses to a light stimulus in a multi-well plate under the same neuroactive treatments as the pERK-labeled images. This juxtaposition highlights the relationship between changes in neural activity and behavior. All images were captured, processed, and conceptualized by the lead author, Dr. Matthew McCarroll.",C,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_17.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_17.png,vitg,2024_17.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_22.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_22.png,clip,2021_22.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_3.png,vith,2021_3.txt,test
ACS Synthetic Biology,2024_8,Which of the following options best describe the cover story?,Yeast engineered to produce bromoform could be used to lessen the,D,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,vitg,2015_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_11.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_11.png,clip,2024_11.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_8.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_8.png,groundtruth,2024_8.txt,train
Crystal Growth & Design,2025_2,Which of the following options best describe the cover story?,"A schematic of stepwise GaN growth, featuring terrace-like structures with atomic-level details: white spheres represent nitrogen atoms, blue for gallium, black for carbon, and yellow for sodium. The illustration highlights GaN",D,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_2.png,vitg,2019_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_3.png,vith,2016_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2020_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2020_8.png,clip,2020_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_2.png,groundtruth,2025_2.txt,train
Developmental Cell,59_7,Which of the following options best describe the cover story?,"On the cover: The image is a graphical representation of the Drosophila Protein Interaction Network 2 that was generated by expressing thousands of individual
tagged proteins and assessing their interacting partners by affinity purification
and mass spectrometry, covering more than half of the proteome. Functionally related
proteins often physically interact with each other and organize into clusters, shown
by the distinct colors. To learn more about how such network maps are a valuable resource
for predicting protein associations and assigning function for poorly studied proteins,
see Bhat et al. Image credit: Guruharsha Bhat.",D,MAC_Bench/Cell/Cover/Developmental Cell/38_2.png,MAC_Bench/Cell/Cover/Developmental Cell/38_2.png,vith,38_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/29_4.png,MAC_Bench/Cell/Cover/Developmental Cell/29_4.png,clip,29_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/45_3.png,MAC_Bench/Cell/Cover/Developmental Cell/45_3.png,ave_2,45_3.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_7.png,MAC_Bench/Cell/Cover/Developmental Cell/59_7.png,groundtruth,59_7.txt,train
Molecular Cell,85_1,Which of the following options best describe the cover story?,"On the cover: RNA modifications decorate RNA molecules, changing their physico-chemical
properties. Ribosomal RNAs (rRNAs) are heavily modified, with more than 200 modified
sites annotated in human rRNAs. In this issue of Molecular Cell, Milenkovic et al. systematically survey the rRNA modification patterns in development, differentiation,
and disease, finding that they represent epitranscriptomic fingerprints of their cells
and tissues of origin. These fingerprints can be used to predict developmental stages,
tissues, cell types, and cancer from as few as 250 reads. Cover artwork by Queralt
Tolosa (https://www.queralttolosa.com).",D,MAC_Bench/Cell/Cover/Molecular Cell/54_4.png,MAC_Bench/Cell/Cover/Molecular Cell/54_4.png,vith,54_4.txt,MAC_Bench/Cell/Cover/Molecular Cell/51_2.png,MAC_Bench/Cell/Cover/Molecular Cell/51_2.png,vitg,51_2.txt,MAC_Bench/Cell/Cover/Molecular Cell/43_1.png,MAC_Bench/Cell/Cover/Molecular Cell/43_1.png,clip,43_1.txt,MAC_Bench/Cell/Cover/Molecular Cell/85_1.png,MAC_Bench/Cell/Cover/Molecular Cell/85_1.png,groundtruth,85_1.txt,train
Bioconjugate Chemistry,2024_11,Which of the following options best describe the cover story?,N-Terminal site-specific biotin and digoxigenin (DIG) conjugated reagents are applied to the clinical anti-drug antibody (ADA) assay development for a VHH antibody using the bridging ELISA format. The site-specific conjugates demonstrated superior purity and homogeneity compared to conventional conjugates and can potentially reduce the possibility of missing detection of ADAs.,D,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_6.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_6.png,ave_1,2013_6.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2014_10.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2014_10.png,clip,2014_10.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,vitg,2013_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_11.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_11.png,groundtruth,2024_11.txt,train
ACS Applied Engineering Materials,2024_5,Which of the following options best describe the cover story?,A mesoporous Ag2ZrO3/GO nanocomposite with a high surface area and abundant available active sides was used for photocatalytic environmental remediation. Molecular dynamics endorses the formation of an interphase between Ag2ZrO3 and GO. This dynamic and visually striking cover art captures (Ag2ZrO3/GO nanocomposite) the essence of light as a multifaceted tool for sustainability and scientific progress.,D,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,clip,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_5.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_4.png,ave_3,2023_4.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_5.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_5.png,groundtruth,2024_5.txt,train
Molecular Pharmaceutics,2024_10,Which of the following options best describe the cover story?,This image represents a painting of a monolayer of lymphatic endothelial cells stained with VE-cadherin and DAPI containing fluorescent nanoparticles. The original painting was created by Shae Shortt. View the article.,D,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_1.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_1.png,clip,2021_1.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_7.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_7.png,ave_1,2024_7.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_10.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_10.png,vitg,2022_10.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_10.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_10.png,groundtruth,2024_10.txt,train
Nature Reviews Endocrinology,20_11,Which of the following options best describe the cover story?,"A discussion of pituitary stem cells, inspired by the Review on p77.
Cover design: Jennie Vallis",B,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_10.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_10.png,vith,17_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_11.png,groundtruth,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_2.png,vitg,17_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,clip,20_1.txt,train
NATURE REVIEWS MICROBIOLOGY,22_1,Which of the following options best describe the cover story?,"The indoor microbiome, inspired by the Review on p742.
Cover design: Amie Fernandez",A,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_1.png,groundtruth,22_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/11_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/11_11.png,vith,11_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_11.png,ave_0,19_11.txt,val
ACS Applied Nano Materials,2025_5,Which of the following options best describe the cover story?,hybrid quantum dot material made of boron nitride (BN) and nitrogen-doped graphene (Hyb-BNQD-NGQD) from bulk BN and polyaniline (PANI) exhibits specific sensing of Pb(II) ions. This material exhibited exceptional selectivity and sensitivity toward Pb(II) ions with a remarkable detection limit of 1 pM.,C,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_2.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_2.png,vitg,2020_2.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_12.png,vith,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_5.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_4.png,clip,2023_4.txt,test
Crystal Growth & Design,2024_21,Which of the following options best describe the cover story?,-wavelength deep ultraviolet emission from AlGaN quantum wires at macrostep edges and AlGaN quantum wells at macrostep terraces. The low dislocation density of AlN templates and dominant luminescence of the high-density quantum wires lead to a high internal quantum efficiency of 70%.,C,MAC_Bench/ACS/Cover/Crystal Growth & Design/2010_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2010_8.png,clip,2010_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_5.png,vith,2016_5.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_21.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_21.png,groundtruth,2024_21.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_7.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_7.png,vitg,2024_7.txt,train
Crystal Growth & Design,2024_9,Which of the following options best describe the cover story?,"A holistic model for accelerated and affordable drug discovery of high bioavailability and improved medicines through the seamless integration of organic synthesis, chemical biology, structural databases, and drug–receptor complexes and assisted by artificial neural networks is presented by Nangia (art by the team of INMYWORK Studio).",D,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_7.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_7.png,vitg,2016_7.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_2.png,clip,2019_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_3.png,vith,2025_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_9.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_9.png,groundtruth,2024_9.txt,train
Trends in Biotechnology,42_3,Which of the following options best describe the cover story?,"Incorporating AI with protein corona studies in lipid nanoparticle research
could help to forecast novel or unexplored formulations that yield targeted coronas.
In
pages 1215–1217 of this issue, Behzadi and Mahmoudi discuss how these approaches
can create desired biological responses and pharmacokinetic profiles. Cover image
from Tina Hofmann.",D,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_9.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_9.png,vitg,42_9.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_1.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_1.png,vith,36_1.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/35_3.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/35_3.png,clip,35_3.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_3.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_3.png,groundtruth,42_3.txt,val
Nature Human Behaviour,8_9,Which of the following options best describe the cover story?,"Unconditional child allowance and families’ spending behaviour
In 2021, the USA provided an unconditional child allowance to most families with children. Using anonymized mobile-location as well as debit and credit card data, Parolin et al. find that the allowance increased spending at childcare centres, health- and personal-care establishments, and grocery stores. On the other hand, there was no evidence that the allowance increased tobacco or alcohol purchases.
See Parolin et al.
Image: designer491/Alamy Stock Photo. Cover design: Bethany Vukomanovic.",A,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_9.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_9.png,groundtruth,8_9.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_5.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_5.png,ave_3,4_5.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,ave_2,4_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_1.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_1.png,clip,4_1.txt,train
Immunity,57_10,Which of the following options best describe the cover story?,"On the cover: Cancer patients often receive a combination of antibodies targeting
PD-L1 and CTLA4, but there is little mechanistic insight into whether and how these
therapeutic approaches synergize in specific disease settings. Franken et al. examine the contribution of anti-CTLA4 to anti-PD-L1 therapy in head and neck squamous
cell carcinoma (HNSCC) and identify CD4+ T cell activation and recruitment from tdLNs are hallmarks of early response to anti-PD-L1
plus anti-CTLA4 in HNSCC. The potential of combination approaches in cancer immunotherapy
is illustrated as a puzzle cube with each facet of the cube containing immune cells
or mechanisms that, when aligned, have the potential of contributing to anti-tumor
immunity. Image created by Amelie Franken.",A,MAC_Bench/Cell/Cover/Immunity/57_10.png,MAC_Bench/Cell/Cover/Immunity/57_10.png,groundtruth,57_10.txt,MAC_Bench/Cell/Cover/Immunity/55_4.png,MAC_Bench/Cell/Cover/Immunity/55_4.png,clip,55_4.txt,MAC_Bench/Cell/Cover/Immunity/35_5.png,MAC_Bench/Cell/Cover/Immunity/35_5.png,vitg,35_5.txt,MAC_Bench/Cell/Cover/Immunity/37_5.png,MAC_Bench/Cell/Cover/Immunity/37_5.png,vith,37_5.txt,train
Journal of Chemical Education,2021_10,Which of the following options best describe the cover story?,"With resurgent lunar exploration and expansion of the commercial space sector, serious scholarship, planning, and resources have focused on extracting and using lunar materials to sustain activity in space. In ""Lunar Resource Harvesting and Manufacturing: Rich Content for the Chemistry Classroom"" (DOI: 10.1021/acs.jchemed.0c01381), Joshua D. Kittle, Michael W. Duff, and John M. Engesser use this engaging, interdisciplinary, space-oriented topic to excite and inspire chemistry students, while reinforcing general chemistry concepts. (Image of moon courtesy of NASA. Image from NASA Moon Mineralogy Mapper showing water detected at high latitudes courtesy of ISRO/NASA/JPL-Caltech/Brown Univ./USGS.)",C,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_9.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_9.png,clip,2016_9.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2019_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2019_11.png,ave_2,2019_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_10.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_10.png,groundtruth,2021_10.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2018_8.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2018_8.png,ave_3,2018_8.txt,test
ACS Infectious Diseases,2024_6,Which of the following options best describe the cover story?,"ELQ-596, a new 3-biaryl endochin-like quinolone, has enhanced potency in vitro against multidrug-resistant Plasmodium falciparum parasites.  ELQ-598, a prodrug of ELQ-596, is more effective vs murine malaria than its progenitor ELQ-331 by 4- to 10-fold, suggesting that lower doses could be used to protect humans against malaria",C,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_8.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_8.png,vitg,2020_8.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_3.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_3.png,clip,2018_3.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_6.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_6.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_6.png,vith,2020_6.txt,train
ACS Energy Letters,2024_6,Which of the following options best describe the cover story?,the most recent approaches to avoid pretreatment with particular emphasis on innovative configurations of well-established industrial electrolyzers and new original approaches.,B,MAC_Bench/ACS/Cover/ACS Energy Letters/2019_3.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2019_3.png,vitg,2019_3.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_6.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2017_10.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2017_10.png,vith,2017_10.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2023_12.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2023_12.png,clip,2023_12.txt,train
Nature Machine Intelligence,6_12,Which of the following options best describe the cover story?,"A detour for neural representations
Training a neural network, which involves optimizing its parameters to reduce a loss function, can be thought of as moving through a landscape with hills of high error and valleys of low error. In the cover image, the red line shows such a trajectory, moving along the gradient towards lower loss. In this issue, Ciceri et al. describe that in successfully learning classification tasks, this training trajectory does not follow a direct route. Instead, the path takes a detour, shown here in brighter red, in which the representation of the data separates in training before later rejoining.
See Ciceri et al.
Image: Marco Gherardi, Università degli Studi di Milano. Cover design: Amie Fernandez",D,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_8.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_8.png,vitg,6_8.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_9.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_9.png,vith,5_9.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_4.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_4.png,clip,2_4.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_12.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_12.png,groundtruth,6_12.txt,train
Nature Neuroscience,27_11,Which of the following options best describe the cover story?,"Mothers’ neuroplasticity at peripartum and childbirth.
During gestation, childbirth, and the postpartum period, dynamic cortical plasticity occurs in mothers’ brains. Paternina-Die, Martínez-García et al. show decreased cortical thickness during pregnancy, which attenuates after birth. In the cover image, the mantle enveloping the mother with child symbolizes the cortical mantle, and the shape of the woman’s brain resembles a baby, serving as a metaphor for the maternal brain. The pixelation overlaying the baby and the background recreates the MRI voxels. The central figure in the image portrays Dr Paternina-Die, who herself became a first-time mother during the completion of this study.
See Paternina-Die, Martínez-García, et al.
Image and cover design: Susana Carmona. Cover Design: Marina Corral Spence.",D,MAC_Bench/Nature/Cover/Nature Neuroscience/27_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_2.png,vitg,27_2.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/6_1.png,MAC_Bench/Nature/Cover/Nature Neuroscience/6_1.png,ave_3,6_1.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/6_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/6_9.png,clip,6_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_11.png,groundtruth,27_11.txt,train
Science Immunology,10_103,Which of the following options best describe the cover story?,"ONLINE COVER Reversing the Hands of Time. Inflammaging is the age-associated increase in systemic inflammation, which can have negative effects on blood cell production and the immune system. Using a mouse model of premature hematopoietic aging, Ramalingam et al. identified thrombospondin-1 (Thbs1) as a driver of age-associated changes to hematopoietic stem cells (HSCs). Deletion of Thbs1 prevented HSC myeloid bias, loss of HSC self-renewal, and systemic signs of inflammaging in aged mice. This month’s cover illustration depicts the process of HSC inflammaging as a pocket watch. Thbs1 gene deletion causes the watch hands to move backwards, which reverses aging-associated HSC defects and turns back the clock on inflammaging. Credit: Rioka Hayama",C,MAC_Bench/Science/Cover/Science Immunology/4_40.png,MAC_Bench/Science/Cover/Science Immunology/4_40.png,vith,4_40.txt,MAC_Bench/Science/Cover/Science Immunology/2_15.png,MAC_Bench/Science/Cover/Science Immunology/2_15.png,clip,2_15.txt,MAC_Bench/Science/Cover/Science Immunology/10_103.png,MAC_Bench/Science/Cover/Science Immunology/10_103.png,groundtruth,10_103.txt,MAC_Bench/Science/Cover/Science Immunology/8_89.png,MAC_Bench/Science/Cover/Science Immunology/8_89.png,ave_2,8_89.txt,train
Science Signaling,2007_408,Which of the following options best describe the cover story?,"COVER This week features a  Perspective on glutamate receptor clustering. The image depicts some of the proteins involved in AMPA receptor clustering. [Image: Christopher Bickel, AAAS]",B,MAC_Bench/Science/Cover/Science Signaling/1_33.png,MAC_Bench/Science/Cover/Science Signaling/1_33.png,vitg,1_33.txt,MAC_Bench/Science/Cover/Science Signaling/2007_408.png,MAC_Bench/Science/Cover/Science Signaling/2007_408.png,groundtruth,2007_408.txt,MAC_Bench/Science/Cover/Science Signaling/8_405.png,MAC_Bench/Science/Cover/Science Signaling/8_405.png,vith,8_405.txt,MAC_Bench/Science/Cover/Science Signaling/9_418.png,MAC_Bench/Science/Cover/Science Signaling/9_418.png,clip,9_418.txt,test
NATURE BIOTECHNOLOGY,42_10,Which of the following options best describe the cover story?,"Point-of-care monitoring
A miniaturized ultrasonic system can provide full-body monitoring and diagnosis. Lin et al. engineer a soft, wireless ultrasound device to measure deep body signals in moving subjects, offering a hands-free solution for continuous, comprehensive health tracking at the point of care.
See Lin et al.
Image: Muyang Lin, University of California San Diego. Cover design: Erin Dewalt.",C,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_4.png,clip,42_4.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_11.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_11.png,vitg,39_11.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_10.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_10.png,groundtruth,42_10.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/36_6.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/36_6.png,vith,36_6.txt,train
Nature Reviews Rheumatology,20_12,Which of the following options best describe the cover story?,"Inspired by the Review on p14.
Cover design: Steven Hall",D,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,vitg,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_12.png,groundtruth,20_12.txt,test
The Journal of Physical Chemistry B,2025_2,Which of the following options best describe the cover story?,"The two-photon absorption of the Green Fluorescent Protein is intrinsically enhanced when utilizing quantum light. The classical and entangled two-photon absorption strengths can be differentially modulated by the protein, enabling precise control over the outcome through adjustments in its local electric field induced by a single amino acid substitution. The image is an artistic representation of the protein absorbing entangled light. Part of the image was generated by artificial intelligence using Kandinsky 2.2. View the article.",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_16.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_16.png,vith,2023_16.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_2.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_2.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_2.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_2.png,vitg,2022_2.txt,train
CELL RESEARCH,34_3,Which of the following options best describe the cover story?,"The image depicts a story that happened during the Warring States. A senior general named Lian Po, loyal to King of the Zhao State, was given a chunk of meat and became re-energized. The cover paper reports that the catabolism of the amino acid glutamine can replenish energy when glucose is depleted. See page 683–706 by Mengqi Li et al. for details.",A,MAC_Bench/Nature/Cover/CELL RESEARCH/34_3.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_3.png,groundtruth,34_3.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/31_4.png,MAC_Bench/Nature/Cover/CELL RESEARCH/31_4.png,vith,31_4.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/33_1.png,MAC_Bench/Nature/Cover/CELL RESEARCH/33_1.png,vitg,33_1.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_9.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_9.png,clip,34_9.txt,train
Trends in Cognitive Sciences,28_6,Which of the following options best describe the cover story?,"Over the past decade, research has demonstrated that interoception
is associated with both the quality and intensity of humans’ affective experiences.
However, we lack a comprehensive understanding of how signals from the body
produce affective states. In this issue of Trends in Cognitive Sciences, M. J. Feldman,
E. Bliss-Moreau, and K. A. Lindquist integrate and build on prior theorizing to discuss
how bodily signals are transduced, transmitted, compressed, and integrated to produce
affective experiences. In doing so, they provide insight into the distinct phenomenology
of affective experiences. Cover image from DrAfter123/Getty Images.",A,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_6.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_6.png,groundtruth,28_6.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_12.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_12.png,clip,20_12.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_3.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_3.png,vith,20_3.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/27_8.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/27_8.png,ave_1,27_8.txt,train
Nature Ecology & Evolution,8_9,Which of the following options best describe the cover story?,"Herbivory in warming oceans
A green sea turtle (Chelonia mydas) feeding in a seagrass meadow. As the oceans warm, some large herbivores are migrating poleward, with potential consequences for their primary source of food. When exposed to excessive grazing, seagrasses across the subtropics are less resilient than their more tropical counterparts, which places them at risk for degradation and eventual habitat collapse.
See Campbell et al
Image: Shane Gross. Cover Design: Allen Beattie.",D,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_8.png,ave_3,5_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_2.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_2.png,vitg,8_2.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_6.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_6.png,clip,4_6.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_9.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_9.png,groundtruth,8_9.txt,test
ACS Catalysis,2024_2,Which of the following options best describe the cover story?,"Cation vacancies are beneficial to enhancing the intrinsic OER activity, and oxygen vacancies are in favor of promoting long-term stability. View the article.",C,MAC_Bench/ACS/Cover/ACS Catalysis/2021_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2021_11.png,vith,2021_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2022_20.png,MAC_Bench/ACS/Cover/ACS Catalysis/2022_20.png,vitg,2022_20.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_2.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2021_17.png,MAC_Bench/ACS/Cover/ACS Catalysis/2021_17.png,clip,2021_17.txt,test
Nature Aging,5_1,Which of the following options best describe the cover story?,"Immune clearance of senescent cells
In this issue, Xinliang Ming, Ze Yang, Yuqiao Huang and colleagues develop a bifunctional peptide that links senescent and natural killer cells to induce immunological removal of senescent cells in fibrosis, injury, cancer and naturally aged mouse models. The cover image depicts the peptide as a scale on which senescent cells (left) are balanced with immune cells (right). The beneficial effects of this immunotherapy approach are symbolized by scattering senescent cells and sprouting tree branches.
See Ming et al.
Image: Ben Wang, Zhejiang University. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Aging/2_8.png,MAC_Bench/Nature/Cover/Nature Aging/2_8.png,clip,2_8.txt,MAC_Bench/Nature/Cover/Nature Aging/5_1.png,MAC_Bench/Nature/Cover/Nature Aging/5_1.png,groundtruth,5_1.txt,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,vith,1_4.txt,MAC_Bench/Nature/Cover/Nature Aging/3_7.png,MAC_Bench/Nature/Cover/Nature Aging/3_7.png,vitg,3_7.txt,test
ACS Chemical Neuroscience,2024_6,Which of the following options best describe the cover story?,"A silver-metallized gold nanorods multicolorimetric sensor array, designed to detect and discriminate dopaminergic agents for assessing nervous system disorders, yielded significant results in simultaneous detection and discrimination of benserazide (Benz), levodopa (",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_3.png,vitg,2020_3.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_7.png,clip,2021_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_6.png,ave_1,2021_6.txt,val
ACS Applied Materials & Interfaces,2025_3,Which of the following options best describe the cover story?,"This cover art depicts a conceptual visualization of an advanced imaging system, featuring an array of microbolometers interfaced with a nanostructured graphene material. The graphic represents high-speed data processing and the dynamic interaction between the microbolometer array and terahertz radiation at the nanoscale.",D,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_2.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_2.png,ave_2,2024_2.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_2.png,vitg,2025_2.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2019_12.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2019_12.png,clip,2019_12.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_3.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_3.png,groundtruth,2025_3.txt,train
Trends in Cancer,10_4,Which of the following options best describe the cover story?,"Gastrointestinal (GI) cancers are highly heterogeneous. In this issue,
de Back et al. discuss how advances in transcriptomic subtyping can help inform
on new GI cancer taxonomies and approaches for clinical implementation. The
cover depicts a vibrant abstract representation of the lower gastrointestinal system,
featuring splashes of reds, deep purples, and a variety of colorful hues that symbolize
the complex nature of tumor heterogeneity within this region. The magnifying glass
highlights the intricate details of the cellular composition and emphasizes the
importance of molecular profiling in uncovering complexities through methods of
transcriptomic subtyping. Cover image designed by Ananya Tirumala, VI4 Artist-in-Residence
Program.",B,MAC_Bench/Cell/Cover/Trends in Cancer/8_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/8_4.png,clip,8_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_4.png,groundtruth,10_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/7_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/7_4.png,vith,7_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_3.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_3.png,vitg,10_3.txt,train
Trends in Genetics,40_9,Which of the following options best describe the cover story?,"In this issue: Genomic resources and profound ecological knowledge
make Littorina snails useful models for speciation studies. Ecotypes and closely related
species adapted to different rocky-shore environments form hybrid zones where
reproductive isolation can be investigated. In this issue, Kerstin Johannesson and
co-authors
show that evolution of reproductive isolation can take different paths and is best
analysed using multi-dimensional frameworks. Contrary to expectations they suggest
that ecotype formation rarely leads to new species and that chromosomal inversions
play a greater role in local adaptation than in completion of reproductive isolation.
Illustration by Patrik Larsson.",D,MAC_Bench/Cell/Cover/Trends in Genetics/29_7.png,MAC_Bench/Cell/Cover/Trends in Genetics/29_7.png,ave_2,29_7.txt,MAC_Bench/Cell/Cover/Trends in Genetics/28_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/28_1.png,clip,28_1.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_8.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_8.png,vitg,40_8.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_9.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_9.png,groundtruth,40_9.txt,train
ACS Central Science,2025_1,Which of the following options best describe the cover story?,"Via synergistic photoredox/Brønsted acid catalysis, a novel three-component radical cascade reaction occurred through a radical addition/ring-opening/PCET-promoted radical–radical coupling protocol, affording an array of valuable enantioenriched",D,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,ave_2,2024_2.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,ave_3,2023_6.txt,MAC_Bench/ACS/Cover/ACS Central Science/2025_1.png,MAC_Bench/ACS/Cover/ACS Central Science/2025_1.png,groundtruth,2025_1.txt,train
NATURE METHODS,21_6,Which of the following options best describe the cover story?,"Tissue histology in 3D
c-Fos+ neuronal mapping of whole mouse brains using DELiVR reveals cancer-induced brain activity changes.
See Kaltenecker et al.
Image: Ali Maximilian Ertürk, Luciano Jan Höher, Helmholtz Munich. Cover design: Thomas Phillips",B,MAC_Bench/Nature/Cover/NATURE METHODS/19_8.png,MAC_Bench/Nature/Cover/NATURE METHODS/19_8.png,clip,19_8.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_6.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_6.png,groundtruth,21_6.txt,MAC_Bench/Nature/Cover/NATURE METHODS/12_7.png,MAC_Bench/Nature/Cover/NATURE METHODS/12_7.png,vitg,12_7.txt,MAC_Bench/Nature/Cover/NATURE METHODS/6_11.png,MAC_Bench/Nature/Cover/NATURE METHODS/6_11.png,ave_1,6_11.txt,train
ACS Applied Materials & Interfaces,2025_6,Which of the following options best describe the cover story?,"The cover showcases custom laser-engineered membranes used for generating lidocaine-loaded nanocapsules via membrane emulsification. These nanoemulsions, based on hydrophobic deep eutectic solvents (DES), enhance drug solubility and bioavailability. The study demonstrates controlled drug release through diffusion and highlights the potential of DES-based nanoemulsions in biomedical drug delivery applications.",A,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_6.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2015_7.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2015_7.png,vitg,2015_7.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2015_6.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2015_6.png,ave_0,2015_6.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_18.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_18.png,clip,2024_18.txt,train
ACS Applied Engineering Materials,2025_2,Which of the following options best describe the cover story?,"Two-way shape memory alloy wideband reconfigurable compound antenna using double spiral technology thermally actuating between its flat state and extended (conical) state to optimize its radio-frequency performance between satellite communication signals and telecommunication signals: This is accurately showing the functionality of the antenna, as no other direct moving parts are needed for the antenna to change states. View the article.",D,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,ave_3,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,ave_2,2024_8.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_2.png,groundtruth,2025_2.txt,train
ACS Macro Letters,2025_1,Which of the following options best describe the cover story?,Allying intramolecular transesterification (the backbiting side reaction) with a compositionally distinct star-shaped macroinitiator is proven particularly effective for the synthesis of cyclic alternating copolymers. The substantially enlarged solubility difference between the cyclic and acyclic part of the product significantly facilitates their separation by simple precipitation treatments.,A,MAC_Bench/ACS/Cover/ACS Macro Letters/2025_1.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2021_3.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2021_3.png,vitg,2021_3.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2016_6.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2016_6.png,vith,2016_6.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2017_12.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2017_12.png,clip,2017_12.txt,train
Trends in Biotechnology,43_1,Which of the following options best describe the cover story?,"Innovators aiming to introduce a new medical device to the market
often face significant challenges with regulatory clearance and reimbursement.
In pages 4 –7 of this issue, Buenz and colleagues provides an overview of these
processes, bridging a crucial gap between device development and patient care.
Cover image created by Jihed Yahyaoui.",B,MAC_Bench/Cell/Cover/Trends in Biotechnology/43_2.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/43_2.png,clip,43_2.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/43_1.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/43_1.png,groundtruth,43_1.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_10.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_10.png,ave_3,36_10.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,vitg,38_12.txt,test
Crystal Growth & Design,2024_5,Which of the following options best describe the cover story?,"Detection mechanism diagram of Na3GaF6:Ho3+,Yb3+@SiO2 based on the fluorescence resonance energy transfer principle.",A,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,vith,2018_1.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,vitg,2019_11.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2003_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2003_1.png,clip,2003_1.txt,test
Structure,32_5,Which of the following options best describe the cover story?,"On the cover: The image shows viral particles of SARS-CoV-2 variants with a close-up
of the spike protein (S) bound to its receptor, human ACE2. Li et al. used cryo-EM to determine the apo S structures and their human ACE2-bound structures
of the newly emerged variants BA.2.86, JN.1, EG.5, EG.5.1, and HV.1. The electrostatic
charge changes and an additional N-glycosylation in BA.2.86 influence its binding
to mAbs. The JN.1 RBD L455S mutation maintains optimal receptor binding and enhances
immune evasion. Image credit: Linjie Li.",A,MAC_Bench/Cell/Cover/Structure/32_5.png,MAC_Bench/Cell/Cover/Structure/32_5.png,groundtruth,32_5.txt,MAC_Bench/Cell/Cover/Structure/27_11.png,MAC_Bench/Cell/Cover/Structure/27_11.png,vitg,27_11.txt,MAC_Bench/Cell/Cover/Structure/19_8.png,MAC_Bench/Cell/Cover/Structure/19_8.png,clip,19_8.txt,MAC_Bench/Cell/Cover/Structure/22_7.png,MAC_Bench/Cell/Cover/Structure/22_7.png,vith,22_7.txt,train
Nature Biomedical Engineering,8_1,Which of the following options best describe the cover story?,"Decoupled antigen binding and CD3 signalling in allogeneic T cells
This issue highlights the engineering of T cells and other immunomodulatory therapeutic cells with augmented functionality, for use to treat HIV, cancers, red-blood-cell disorders and injured, inflamed tissue.
The cover illustrates that allogeneic T cells can be engineered with a T cell receptor that decouples antigen-mediated T cell activation from T cell cytotoxicity.
See Kapetanovic et al.
Image: Daniel Pöschl, ETH Zurich. Cover design: Alex Wing.",D,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,vitg,7_4.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_9.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_9.png,ave_2,8_9.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_2.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_2.png,clip,5_2.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_1.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_1.png,groundtruth,8_1.txt,test
Analytical Chemistry,2025_3,Which of the following options best describe the cover story?,"A new platform combines high-resolution ion mobility and low-temperature vibrational ion spectroscopy to accurately identify chemical compounds. Precise identifications of analytes are made by measuring their infrared spectra using a messenger-tagging approach with nitrogen. This enables infrared spectral measurements to be incorporated into analytical workflows on practical time scales (credit: Shutterstock IDs 547871221, 1060615994, and 2248636519).",D,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_10.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_10.png,vitg,2019_10.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_20.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_20.png,vith,2020_20.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_20.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_20.png,clip,2019_20.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_3.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_3.png,groundtruth,2025_3.txt,test
Trends in Ecology & Evolution,39_4,Which of the following options best describe the cover story?,"As CO2 levels increase, plants produce more biomass. However, the
concentration of essential elements is reduced. This means herbivores such as the
pipevine swallowtail caterpillar (Battus philenor) pictured, are feeding on lower quality
plant tissue – a phenomenon referred to as “nutrient dilution”. On pages 809–820,
Michael Kaspari and Ellen Welti argue that nutrient dilution could be a key driver
in global
herbivore declines. Image credit: David Rintoul.",D,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/33_7.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/33_7.png,clip,33_7.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/35_9.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/35_9.png,vitg,35_9.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_4.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_4.png,ave_2,36_4.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_4.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_4.png,groundtruth,39_4.txt,train
Nature Microbiology,10_1,Which of the following options best describe the cover story?,"Shigella invades via host filopodia
: Human enteric defensin 5 (HD5), by interacting with colonic epithelial receptor P2Y11, induces rapid formation of filopodial extensions that capture Shigella, a major human enteroinvasive pathogen that is able to exploit these filopodia for invasion, revealing a mechanism for HD5-facilitated bacterial invasion. GFP-expressing Shigella are cyan, actin filaments are red and nuclei are blue (DAPI).
See Xu et al.
Image: Dan Xu, Xi'an Jiaotong University. Cover design: Laoise Mac Gabhann",C,MAC_Bench/Nature/Cover/Nature Microbiology/2_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/1_10.png,MAC_Bench/Nature/Cover/Nature Microbiology/1_10.png,ave_1,1_10.txt,MAC_Bench/Nature/Cover/Nature Microbiology/10_1.png,MAC_Bench/Nature/Cover/Nature Microbiology/10_1.png,groundtruth,10_1.txt,MAC_Bench/Nature/Cover/Nature Microbiology/3_8.png,MAC_Bench/Nature/Cover/Nature Microbiology/3_8.png,ave_2,3_8.txt,train
Nature Reviews Chemistry,8_4,Which of the following options best describe the cover story?,"The question of how life began has intrigued people for many years. While we may never know the answer, several research avenues exist – each with their own theories and starting conditions. Common grounds between different theories do exist, such as the need for membranes forming compartment used to contain and protect the crucial ingredients of life. How these compartments were formed is also heavily debated. It is possible that simple amphiphiles — synthesised in dense molecular clouds of the interstellar medium — were deposited on early Earth via meteors and comets before eventually self-assembling into membranes and the phospholipid bilayers as we know them today. See Bocková et al.
Image: Carl Conway; Cover design: Carl Conway",D,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_7.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_7.png,vitg,6_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/5_3.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/5_3.png,vith,5_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,clip,7_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_4.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_4.png,groundtruth,8_4.txt,train
Molecular Pharmaceutics,2024_8,Which of the following options best describe the cover story?,"As a showcase of the union of computer simulation and experimental work, this cover art captures the complex interaction of cationic polymers with RNA. It marks the progress from traditional trial and error to intelligent design in developing precise polymeric drug delivery systems, demonstrating a significant advance in drug carrier technology. View the article.",D,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,clip,2020_4.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_6.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_6.png,vith,2020_6.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_7.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_7.png,vitg,2021_7.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_8.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_8.png,groundtruth,2024_8.txt,train
The Journal of Physical Chemistry B,2025_9,Which of the following options best describe the cover story?,"Collage of artwork from recent issues of J. Phys. Chem. B. Background: Polarizing Perspectives: Ion- and Dipole-Induced Dipole Interactions Dictate Bulk Nanobubble Stability (J. Phys. Chem. B 2024, 128 (29), 7263–7270. DOI: 10.1021/acs.jpcb.4c03973). Top row from left: Structural Rearrangements of Pigeon Cryptochrome 4 Undergoing a Complete Redox Cycle (J. Phys. Chem. B 2024, 128 (16), 3844–3855. DOI: 10.1021/acs.jpcb.4c00424); Probing the Molecular Interactions of Electrochemically Reduced Vitamin B2 with CO2 (J. Phys. Chem. B 2024, 128 (44), 10853–10860. DOI: 10.1021/acs.jpcb.4c05952). Bottom row from left: Supramolecular Chirality Achieved by Assembly of Small π-Molecules of Octahydrobinaphtols with Axial Chirality (J. Phys. Chem. B 2024, 128 (18), 4464–4471. DOI: 10.1021/acs.jpcb.3c08464); Atomistic Insight into the Lipid Nanodomains of Synaptic Vesicles (J. Phys. Chem. B 2024, 128 (11), 2707–2716. DOI: 10.1021/acs.jpcb.3c07982); Genetic Algorithm for Automated Parameterization of Network Hamiltonian Models of Amyloid Fibril Formation (J. Phys. Chem. B 2024, 128 (8), 1854–1865. DOI: 10.1021/acs.jpcb.3c07322).",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_29.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_29.png,vitg,2023_29.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_9.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_9.png,groundtruth,2025_9.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_27.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_27.png,ave_2,2022_27.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2024_41.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2024_41.png,clip,2024_41.txt,test
Trends in Genetics,40_11,Which of the following options best describe the cover story?,"By virtue of their ability to scan and target partial DNA binding motifs on
nucleosomes in chromatin, pioneer transcription factors can act as master regulators
of
development. On pp. 134–148, Amandine Barral and Ken Zaret describe how pioneer
factors guide cell fate transitions during development. They discuss the structural
and
functional characteristics of pioneer factors that allow them to bind and initiate
opening
of silent chromatin and the consequences for chromatin dynamics and gene expression.
Illustration by Amandine Barral.",A,MAC_Bench/Cell/Cover/Trends in Genetics/40_11.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_11.png,groundtruth,40_11.txt,MAC_Bench/Cell/Cover/Trends in Genetics/32_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/32_1.png,vitg,32_1.txt,MAC_Bench/Cell/Cover/Trends in Genetics/34_3.png,MAC_Bench/Cell/Cover/Trends in Genetics/34_3.png,clip,34_3.txt,MAC_Bench/Cell/Cover/Trends in Genetics/27_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/27_1.png,vith,27_1.txt,train
iScience,27_6,Which of the following options best describe the cover story?,"On the cover: The main purpose of this study by Zhou et al. is to address IPDA-related issues, which require different probe sequences for different
subtypes of HIV-1. The ultimate goal of this field of research is the accurate measurement
of viral reservoirs, including different subtypes and sequences. The different colors
of the viruses on this cover represent the different subtypes, which are firmly enclosed
in a net, i.e., the meaning of “all in one net.” Image credit: Xinyu Zhang.",A,MAC_Bench/Cell/Cover/iScience/27_6.png,MAC_Bench/Cell/Cover/iScience/27_6.png,groundtruth,27_6.txt,MAC_Bench/Cell/Cover/iScience/23_9.png,MAC_Bench/Cell/Cover/iScience/23_9.png,clip,23_9.txt,MAC_Bench/Cell/Cover/iScience/10_1.png,MAC_Bench/Cell/Cover/iScience/10_1.png,vitg,10_1.txt,MAC_Bench/Cell/Cover/iScience/12_1.png,MAC_Bench/Cell/Cover/iScience/12_1.png,ave_1,12_1.txt,train
Chemical Research in Toxicology,2024_1,Which of the following options best describe the cover story?,Convolutional Neural Network for Sustainable Detection of Arsenic in Environmental Samples and Arsenic Albumin: An Innovative Artificial Intelligence Approach in Toxicology,D,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_3.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_3.png,vitg,2017_3.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_11.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_11.png,vith,2024_11.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2020_5.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2020_5.png,clip,2020_5.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_1.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_1.png,groundtruth,2024_1.txt,train
Nature Mental Health,2_6,Which of the following options best describe the cover story?,"Default-mode network and dementia
Alzheimer’s disease and dementia are associated with changes in the default-mode network (DMN), the distributed set of regions that are active when an individual is not focused on an external task or stimuli. In this issue, Ereira et al. demonstrate that altered DMN connectivity can be used to identify future dementia incidence at the individual level. The cover of the July issue alludes to the possibility of using brain activation patterns in the DMN to predict dementia and its potential for early detection and intervention.
See Ereira et al.
Image and cover design: Marina Spence",A,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,groundtruth,2_6.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,vitg,2_10.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,ave_2,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_12.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_12.png,clip,2_12.txt,train
Cell Chemical Biology,31_7,Which of the following options best describe the cover story?,"On the cover: Dual targeting of proteins (orange and blue) on the same cell surface
via bispecific antibodies (pink beige) holds great therapeutic promise with novel
modes of action that are rapidly advancing towards the clinic. Oslund et al. review the therapeutic impact of cis-targeting bispecific antibodies (pink beige)
in the clinic and their emerging applications and highlight features for enhancing
cis-targeting bispecific therapeutic development. Cover art created by Yi Zheng (yizhengillustration).",C,MAC_Bench/Cell/Cover/Cell Chemical Biology/24_3.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/24_3.png,vitg,24_3.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_9.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_9.png,vith,18_9.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png,groundtruth,31_7.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_12.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_12.png,clip,31_12.txt,test
Nature Climate Change,14_1,Which of the following options best describe the cover story?,"Frogs in a drying world
The risk of drying to animal species remains an understudied element of climate change, which is particularly important for water-sensitive groups such as anurans (frogs and toads). Writing in this issue of Nature Climate Change, Wu and colleagues map the global impacts of warming on anurans, demonstrating how drought will amplify the negative impacts of warming on anurans.
See Wu et al. and Research Briefing
Image: Jasmine Vink. Cover design: Vanitha Selvarajan",C,MAC_Bench/Nature/Cover/Nature Climate Change/12_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/12_10.png,clip,12_10.txt,MAC_Bench/Nature/Cover/Nature Climate Change/11_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/11_10.png,vitg,11_10.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_1.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_1.png,groundtruth,14_1.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_10.png,vith,14_10.txt,test
Molecular Plant,17_3,Which of the following options best describe the cover story?,"On the cover: The different colored shapes depict the SA-induced NPR1, as a dimer, fused to TurboID
with the labeling radius highlighted in green and to GFP that is recognized by the
GFP nanobody-MNase used in greenCUT&RUN. When bound to NPR1-GFP, the GFP nanobody-MNase
cleaves the genomic loci bound by NPR1-GFP through its association with the TGA transcription
factor (TGA). The cover image illustrates, on the one side, the identification of
the nuclear partners of NPR1, while on the other side, the identification of genomic
targets of NPR1. Image by Jordan Powers.",B,MAC_Bench/Cell/Cover/Molecular Plant/9_12.png,MAC_Bench/Cell/Cover/Molecular Plant/9_12.png,vitg,9_12.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_3.png,MAC_Bench/Cell/Cover/Molecular Plant/17_3.png,groundtruth,17_3.txt,MAC_Bench/Cell/Cover/Molecular Plant/9_1.png,MAC_Bench/Cell/Cover/Molecular Plant/9_1.png,vith,9_1.txt,MAC_Bench/Cell/Cover/Molecular Plant/10_5.png,MAC_Bench/Cell/Cover/Molecular Plant/10_5.png,clip,10_5.txt,train
Nature Reviews Nephrology,20_9,Which of the following options best describe the cover story?,"The varied roles of non-haematopoietic cells, inspired by the Review on p206.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,vitg,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_9.png,groundtruth,20_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_10.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_10.png,vith,17_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_3.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_3.png,clip,17_3.txt,train
Industrial & Engineering Chemistry Research,2024_36,Which of the following options best describe the cover story?,high hydrogen permeable ZIF-8 membranes offer great application potential for extracting hydrogen from coke oven gas.,D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,vitg,2021_45.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_6.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_6.png,clip,2023_6.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,ave_2,2022_11.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,groundtruth,2024_36.txt,val
Nature Catalysis,7_12,Which of the following options best describe the cover story?,"Reconstructing copper
In their work, Raffaella Buonsanti and colleagues investigate the mechanism of reconstruction of copper CO2 reduction electrocatalysts. Spectroscopic methods support a dissolution-redeposition mechanism involving solution-based Cu(I) species which are further elucidated as copper carbonyl and oxalate complexes using density functional theory.
See Vavra et al.
Cover design: Alex Whitworth.",C,MAC_Bench/Nature/Cover/Nature Catalysis/5_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/5_3.png,ave_2,5_3.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_3.png,ave_3,2_3.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_12.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_12.png,groundtruth,7_12.txt,MAC_Bench/Nature/Cover/Nature Catalysis/1_1.png,MAC_Bench/Nature/Cover/Nature Catalysis/1_1.png,clip,1_1.txt,val
Bioconjugate Chemistry,2024_3,Which of the following options best describe the cover story?,"for combination cancer therapy. A controlled adjustment of their ligand layer composition allows for several formulations to be obtained with high affinity to integrin αvβ3, a transmembrane receptor that is overexpressed in many types of cancer.",C,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,vitg,2013_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2023_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_3.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,ave_0,2010_3.txt,test
ACS ES&T Water,2024_8,Which of the following options best describe the cover story?,"This work provides a comprehensive overview of pollution in Chinese water environments and exposure risks of pollutants to wetland birds in aquatic ecosystems. Migratory birds can be important biovectors of persistent and bioaccumulative pollutants, which may be an essential geochemical cycling process in addition to atmospheric deposition.",A,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2023_5.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2023_5.png,ave_3,2023_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_11.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_11.png,ave_2,2022_11.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_1.png,clip,2021_1.txt,train
Nature Microbiology,9_2,Which of the following options best describe the cover story?,"Best practices in microbiology
Best practices in microbiology range from learning sterile techniques or streaking your bacterial strain of choice, to defining frameworks to facilitate data sharing. These practices guide us towards more robust, reproducible, ethical and sustainable science and facilitate major advances. This month’s focus issue features a set of Perspectives that discuss best practices for microbiome research, specifically synthetic communities and the design of clinical trials for probiotics and prebiotics. To accompany the issue, we present a Series hosting an evolving collection of articles that will expand over time to highlight tools, frameworks and resources that push us towards better microbiology research.
See Editorial
Image and cover design: Debbie Maizels",C,MAC_Bench/Nature/Cover/Nature Microbiology/2_8.png,MAC_Bench/Nature/Cover/Nature Microbiology/2_8.png,vitg,2_8.txt,MAC_Bench/Nature/Cover/Nature Microbiology/3_10.png,MAC_Bench/Nature/Cover/Nature Microbiology/3_10.png,vith,3_10.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_2.png,groundtruth,9_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/4_12.png,MAC_Bench/Nature/Cover/Nature Microbiology/4_12.png,clip,4_12.txt,test
Industrial & Engineering Chemistry Research,2024_51,Which of the following options best describe the cover story?,Unveiling hydrotransport dynamics: Enhanced bitumen recovery through advanced computational fluid dynamics and population balance modeling. Investigating the influence of slurry velocities and bubble size on bitumen distribution in the pipeline transport of oil sand ores.,D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_43.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_43.png,ave_2,2022_43.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_2.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_2.png,ave_1,2023_2.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,clip,2022_11.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_51.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_51.png,groundtruth,2024_51.txt,train
Developmental Cell,59_22,Which of the following options best describe the cover story?,"On the cover: Confocal microscopy image of a mouse embryonic pancreatic explant showing
pancreatic epithelial branches (green) and acinar progenitor cells (purple). At this
stage, pancreatic duct cells are marked by Prox1 (green) and form secondary branches,
which end with acinar structures positive for Integrin alpha6 (purple). To learn more
about how embryonic pancreatic tissue undergoes branching morphogenesis, see Darrigrand et al. Image credit: Jean-Francois Darrigrand.",D,MAC_Bench/Cell/Cover/Developmental Cell/58_18.png,MAC_Bench/Cell/Cover/Developmental Cell/58_18.png,vitg,58_18.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,clip,59_20.txt,MAC_Bench/Cell/Cover/Developmental Cell/40_4.png,MAC_Bench/Cell/Cover/Developmental Cell/40_4.png,vith,40_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_22.png,MAC_Bench/Cell/Cover/Developmental Cell/59_22.png,groundtruth,59_22.txt,test
Current Biology,34_6,Which of the following options best describe the cover story?,"On the cover: Sea robins are unusual fish that evolved leg-like appendages that they
use to “walk” along the seafloor. In this issue, two papers from the Bellono and Kingsley labs use sea robins to investigate the origins of novel traits. In the first paper,
the researchers discover that sea robins develop legs from fins using genes that are
also involved in human limb formation. In the second paper, the team describes that
sea robins specialize legs as sensory organs that detect chemicals and touch to find
buried prey. Image by Mike Jones (https://mikejonesdive.com/).",B,MAC_Bench/Cell/Cover/Current Biology/32_3.png,MAC_Bench/Cell/Cover/Current Biology/32_3.png,vith,32_3.txt,MAC_Bench/Cell/Cover/Current Biology/34_6.png,MAC_Bench/Cell/Cover/Current Biology/34_6.png,groundtruth,34_6.txt,MAC_Bench/Cell/Cover/Current Biology/27_7.png,MAC_Bench/Cell/Cover/Current Biology/27_7.png,clip,27_7.txt,MAC_Bench/Cell/Cover/Current Biology/22_11.png,MAC_Bench/Cell/Cover/Current Biology/22_11.png,vitg,22_11.txt,train
Journal of the American Chemical Society,2024_49,Which of the following options best describe the cover story?,"An asymmetric olefin–sulfonylimine coupling via paired electrocatalysis is presented. In this protocol, Co-catalyzed hydrogen-atom transfer on the anode and Ni-catalyzed sulfonylimine reduction on the cathode were seamlessly cross-coupled, enabling the formation of chiral amine products with high enantioselectivity (up to 96% ee). View the article.",A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_49.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_49.png,groundtruth,2024_49.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_3.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_3.png,vith,2010_3.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_7.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_7.png,clip,2010_7.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,vitg,2010_30.txt,train
ACS Infectious Diseases,2025_1,Which of the following options best describe the cover story?,"This study models the cyclases/histidine kinases associated with the sensory extracellular (CHASE) domain of the sensor protein DspS in Pseudomonas aeruginosa. It identifies a potential binding site for cis-2-decenoic acid (CDA) and discovers two novel biofilm-dispersing compounds, providing important insights into CDA recognition. The background image, featuring bacterial colonies, was created using Adobe Creative Cloud.",A,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2025_1.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2022_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2022_7.png,vith,2022_7.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_3.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_3.png,clip,2023_3.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_6.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_6.png,vitg,2024_6.txt,val
Immunity,57_7,Which of the following options best describe the cover story?,"On the cover: In this issue, Billipp et al. report the identification of a circuit wherein, upon detection of helminth infection,
tuft cells secrete acetylcholine that acts on neighboring epithelial cells to stimulate
chloride secretion. This then promotes the “weep” response and restricts helminth
infection, independently of other type 2 cells. The sentinel and effector functions
of epithelial tuft cells in host defense in the intestine are illustrated in the form
of Roman soldiers, where the apical “tuft” of microvilli are the plume on the centurion’s
helmet. An accompanying paper by Ndjim, Gasmi, Herbert, et al. reports similar findings.
Cover image by Lauren Hostette.",C,MAC_Bench/Cell/Cover/Immunity/31_6.png,MAC_Bench/Cell/Cover/Immunity/31_6.png,vitg,31_6.txt,MAC_Bench/Cell/Cover/Immunity/32_4.png,MAC_Bench/Cell/Cover/Immunity/32_4.png,vith,32_4.txt,MAC_Bench/Cell/Cover/Immunity/57_7.png,MAC_Bench/Cell/Cover/Immunity/57_7.png,groundtruth,57_7.txt,MAC_Bench/Cell/Cover/Immunity/45_1.png,MAC_Bench/Cell/Cover/Immunity/45_1.png,clip,45_1.txt,train
Molecular Therapy,32_10,Which of the following options best describe the cover story?,"On the cover: Immunofluorescent labeling of nerves marked by tyrosine hydroxylase (blue) wrapping
around an adipocyte (orange, autofluorescence) of a diet-induced obese mouse following
adipocyte-specific Rec2-AAV-mediated overexpression of nerve growth factor (NGF),
which increased the presence of these neuro-adipose nexus (NAN) structures, as captured
on a Leica Stellaris confocal by Jake W. Willows, in collaboration with Blaszkiewicz and Townsend.",B,MAC_Bench/Cell/Cover/Molecular Therapy/25_7.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_7.png,vith,25_7.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_10.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_10.png,groundtruth,32_10.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_16.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_16.png,vitg,32_16.txt,MAC_Bench/Cell/Cover/Molecular Therapy/25_12.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_12.png,clip,25_12.txt,train
ACS Nano,2025_4,Which of the following options best describe the cover story?,"This image depicts ""fuzzy"" silicon-shelled nanocapsules with a heterogeneous size distribution being ""weighed"" by charge detection mass spectrometry (CDMS), a technique capable of individual particle mass measurements. This image was generated using iterative prompts to openart.ai.",C,MAC_Bench/ACS/Cover/ACS Nano/2024_41.png,MAC_Bench/ACS/Cover/ACS Nano/2024_41.png,ave_1,2024_41.txt,MAC_Bench/ACS/Cover/ACS Nano/2024_36.png,MAC_Bench/ACS/Cover/ACS Nano/2024_36.png,vitg,2024_36.txt,MAC_Bench/ACS/Cover/ACS Nano/2025_4.png,MAC_Bench/ACS/Cover/ACS Nano/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/ACS Nano/2024_8.png,MAC_Bench/ACS/Cover/ACS Nano/2024_8.png,clip,2024_8.txt,train
Developmental Cell,59_9,Which of the following options best describe the cover story?,"On the cover: The image depicts “Auto-Pack” (Autophagosome-Packman, in yellow) engulfing
misfolded proteins (in red) from the labyrinth of the endoplasmic reticulum (ER) through
a process known as ER-phagy (autophagy of the endoplasmic reticulum). To learn more
about how ER-phagy is activated in response to protein misfolding, see De Leonibus et al. Image credit: Gennaro Di Bonito, Marianna Maddaluno, and Chiara De Leonibus.",B,MAC_Bench/Cell/Cover/Developmental Cell/46_5.png,MAC_Bench/Cell/Cover/Developmental Cell/46_5.png,vitg,46_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_9.png,MAC_Bench/Cell/Cover/Developmental Cell/59_9.png,groundtruth,59_9.txt,MAC_Bench/Cell/Cover/Developmental Cell/48_6.png,MAC_Bench/Cell/Cover/Developmental Cell/48_6.png,clip,48_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/19_1.png,MAC_Bench/Cell/Cover/Developmental Cell/19_1.png,vith,19_1.txt,train
ACS Synthetic Biology,2024_2,Which of the following options best describe the cover story?,that can directly measure gene transfer in soil using gas chromatography–mass spectrometry.,D,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,vith,2015_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2022_9.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2022_9.png,vitg,2022_9.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_4.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_2.png,groundtruth,2024_2.txt,train
Nature Reviews Cardiology,21_1,Which of the following options best describe the cover story?,"Cardiac health and disease in Latin America and Africa, inspired by the Review on p849.
Cover design: Vicky Summersby",A,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_1.png,groundtruth,21_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_1.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_1.png,clip,19_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_7.png,ave_1,18_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_2.png,vitg,19_2.txt,train
Current Biology,34_22,Which of the following options best describe the cover story?,"On the cover: In this issue, Drury et al. deploy a new modeling approach and show that the availability of open niches influences
the pace of phenotypic evolution across all birds. This image shows a little bee-eater
(Merops pusillus), an African invertivore (one of the groups with a particularly strong response to
changing niche availability). Photo by Jonathan Drury.",B,MAC_Bench/Cell/Cover/Current Biology/21_5.png,MAC_Bench/Cell/Cover/Current Biology/21_5.png,vith,21_5.txt,MAC_Bench/Cell/Cover/Current Biology/34_22.png,MAC_Bench/Cell/Cover/Current Biology/34_22.png,groundtruth,34_22.txt,MAC_Bench/Cell/Cover/Current Biology/18_1.png,MAC_Bench/Cell/Cover/Current Biology/18_1.png,vitg,18_1.txt,MAC_Bench/Cell/Cover/Current Biology/30_18.png,MAC_Bench/Cell/Cover/Current Biology/30_18.png,clip,30_18.txt,test
ACS Applied Polymer Materials,2024_5,Which of the following options best describe the cover story?,"Fluorescent sugar-hydrogel, developed using the functionalization of chitosan and an anthracene derivative, which shows solvent-dependent aggregation-based exciplex emission in gel networks at a normal temperature. The background image was created using DALL·E, an AI-powered image generation tool by OpenAI.",D,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_24.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_24.png,vitg,2024_24.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_4.png,clip,2023_4.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_6.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_5.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_5.png,groundtruth,2024_5.txt,train
Lab Animal,53_11,Which of the following options best describe the cover story?,"3D printing of a murine MRI platform
Positioning and maintaining small animals for imaging over time requires a means to secure the head, maintain the animal's body temperature and facilitate delivery of anesthesia if needed. A new Article describes an open-source, customizable 3D printable cradle design that can be used for brain imaging in awake mice and anesthetized mice and rats.
See Yaghmazadeh et al.
Cover image: Alex Whitworth. Cover design: Alex Whitworth",C,MAC_Bench/Nature/Cover/Lab Animal/49_7.png,MAC_Bench/Nature/Cover/Lab Animal/49_7.png,clip,49_7.txt,MAC_Bench/Nature/Cover/Lab Animal/47_5.png,MAC_Bench/Nature/Cover/Lab Animal/47_5.png,vith,47_5.txt,MAC_Bench/Nature/Cover/Lab Animal/53_11.png,MAC_Bench/Nature/Cover/Lab Animal/53_11.png,groundtruth,53_11.txt,MAC_Bench/Nature/Cover/Lab Animal/47_4.png,MAC_Bench/Nature/Cover/Lab Animal/47_4.png,vitg,47_4.txt,val
Crystal Growth & Design,2024_4,Which of the following options best describe the cover story?,supramolecular polymeric motifs are combined in one crystal to produce the platforms for multimodal thermally tuned blue-to-green and/or NIR photoluminescence. The background of the cover image was generated by artificial intelligence (AI) using Microsoft Copilot.,C,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_3.png,vitg,2025_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,clip,2019_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_4.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_9.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_9.png,vith,2024_9.txt,train
Nature Electronics,7_1,Which of the following options best describe the cover story?,"A new quantum standard of resistance
High-accuracy measurements of Hall resistance quantization in the quantum anomalous Hall effect regime on a device based on a magnetically doped topological insulator show that the system could provide a quantum resistance standard at zero external magnetic field. The optical differential interference contrast microscopy image on the cover shows the quantum anomalous Hall effect device, which is fabricated from the topological insulator vanadium-doped (Bi,Sb)2Te3.
See Patel et al. and News & Views by Callegaro
Image: Kajetan Fijalkowski, University of Würzburg. Cover design: Lauren Heslop.",D,MAC_Bench/Nature/Cover/Nature Electronics/2_8.png,MAC_Bench/Nature/Cover/Nature Electronics/2_8.png,vitg,2_8.txt,MAC_Bench/Nature/Cover/Nature Electronics/4_7.png,MAC_Bench/Nature/Cover/Nature Electronics/4_7.png,ave_0,4_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_3.png,MAC_Bench/Nature/Cover/Nature Electronics/7_3.png,clip,7_3.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_1.png,MAC_Bench/Nature/Cover/Nature Electronics/7_1.png,groundtruth,7_1.txt,train
Macromolecules,2024_23,Which of the following options best describe the cover story?,"The imbibition of star-shaped polyisoprenes within nanoporous alumina are explored using in situ nano-dielectric spectroscopy. Polymer topology strongly affects the adsorption and imbibition kinetics. The adsorption of stars is substantially longer from linear chains. Depending on molar mass and pore size, adsorption times can exceed 12 days.",B,MAC_Bench/ACS/Cover/Macromolecules/2014_11.png,MAC_Bench/ACS/Cover/Macromolecules/2014_11.png,clip,2014_11.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_23.png,MAC_Bench/ACS/Cover/Macromolecules/2024_23.png,groundtruth,2024_23.txt,MAC_Bench/ACS/Cover/Macromolecules/2023_10.png,MAC_Bench/ACS/Cover/Macromolecules/2023_10.png,vitg,2023_10.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_10.png,MAC_Bench/ACS/Cover/Macromolecules/2014_10.png,ave_2,2014_10.txt,train
Nature Reviews Clinical Oncology,22_2,Which of the following options best describe the cover story?,"Off-the-shelf cell therapies for patients with cancer, inspired by the Review on p10.
Cover design: Carl Conway",A,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/22_2.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/22_2.png,groundtruth,22_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_10.png,vith,18_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_7.png,vitg,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/12_3.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/12_3.png,clip,12_3.txt,train
NATURE REVIEWS NEUROSCIENCE,25_6,Which of the following options best describe the cover story?,"‘Decoding speech’, inspired by the Review on p473.
Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,ave_1,15_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_8.png,vitg,25_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_6.png,groundtruth,25_6.txt,val
ACS Infectious Diseases,2024_5,Which of the following options best describe the cover story?,By integrating DNA-functionalized Au nanoparticles in the isothermal DNA amplification of,C,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_3.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_3.png,vith,2018_3.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_5.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_5.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_1.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_1.png,clip,2023_1.txt,train
ACS Applied Engineering Materials,2024_11,Which of the following options best describe the cover story?,"Inspired by the layered microstructure of nacre (mother of pearl), the study shows that graphene–polyethylene nanocomposites confer excellent shock dissipation and spall strength, especially when there is grafting between the filler (graphene) and the matrix (polyethylene), ushering exploration of biomimetic nanocomposites for protection under extreme conditions.",C,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_11.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_11.png,ave_1,2023_11.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_11.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_6.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_6.png,clip,2023_6.txt,train
Trends in Microbiology,32_12,Which of the following options best describe the cover story?,"The design of the cover image is based on Newton's cradle, which
is demonstrative of the conservation of momentum and energy. It is essential to
understand how microbes interact, assemble, and persist within microbial communities.
In the context of abundant and diverse commensal microbes in the host, enterococci,
as depicted as the lifted and released ball, drive the proliferation, pathogenicity
or
persistence of representative pathogens such as S. aureus, C. difficile and E. coli via metabolic cross-feeding, upregulation of virulence and biofilm formation, thus
influencing the progression of bacterial infections and affecting treatment options.
This
driving role of enterococci in polymicrobial infections is the subject of the review
by Xu
and colleagues. Image courtesy: Kui Zhu and Wenjiao Xu",B,MAC_Bench/Cell/Cover/Trends in Microbiology/32_11.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_11.png,vith,32_11.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_12.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_12.png,groundtruth,32_12.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/31_5.png,MAC_Bench/Cell/Cover/Trends in Microbiology/31_5.png,vitg,31_5.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/26_8.png,MAC_Bench/Cell/Cover/Trends in Microbiology/26_8.png,clip,26_8.txt,train
Journal of Chemical Education,2021_6,Which of the following options best describe the cover story?,"Vivid illustrations of phase phenomena can be achieved in the classroom or laboratory using simple mixtures of liquids. In this issue, J. Charles Williamson presents three papers on liquid–liquid demonstrations that reveal different facets of phase transitions and equilibria. ""Phase Equilibria and the Lever Rule"" (DOI: 10.1021/acs.jchemed.0c01517) details preparation of an immiscible hexaphasic liquid mixture (shown on the cover separating after agitation) and discusses the visual verification of the lever rule using a system of partially miscible isobutyric acid and water (IAW) plus dye. ""Critical Opalescence"" (DOI: 10.1021/acs.jchemed.0c01518) describes how a single-phase IAW sample changes from colorless to pale blue to turbid white as it cools down toward the critical temperature, demonstrating a universal critical behavior. Finally, ""Spinodal Decomposition"" (DOI: 10.1021/acs.jchemed.0c01519) explains how slow cooling of that same IAW sample into the two-phase region initiates a rarely observed phase separation process: thermodynamic instability over the entire liquid sample results in transient structural order that can be observed in real time with a laser diffraction technique.",D,MAC_Bench/ACS/Cover/Journal of Chemical Education/2018_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2018_1.png,clip,2018_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2012_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2012_6.png,vitg,2012_6.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2015_9.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2015_9.png,ave_0,2015_9.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_6.png,groundtruth,2021_6.txt,train
ACS Applied Polymer Materials,2024_3,Which of the following options best describe the cover story?,"The cover art depicts a biomimetic 3D-printed armored structure inspired by armadillo shells for durable superhydrophobic surfaces. It showcases hexagonal patterns protecting inner hydrophobic nanoparticles, repelling water droplets. The design illustrates the approach of integrating 3D printing with nanomaterial surface treatments to create wear-resistant, water-repellent coatings for harsh environments.",A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_14.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_14.png,clip,2024_14.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_6.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_6.png,vith,2023_6.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_12,Which of the following options best describe the cover story?,"The art of therapeutic mRNA design, inspired by the Review on p67.
Cover design: S. Harris",B,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,vitg,23_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_12.png,groundtruth,23_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_7.png,vith,21_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,clip,19_12.txt,train
ACS Biomaterials Science & Engineering,2024_11,Which of the following options best describe the cover story?,", first fabricating frameworks of hydrogel models by stereolithography and subsequently modifying the fabricated models with hydroxyapatite.",D,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2015_9.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2015_9.png,vitg,2015_9.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2020_5.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2020_5.png,clip,2020_5.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2016_11.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2016_11.png,vith,2016_11.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2024_11.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2024_11.png,groundtruth,2024_11.txt,test
Cell Stem Cell,31_3,Which of the following options best describe the cover story?,"On the cover: In this issue, Pang et al. report a method for generating human medullary spinal trigeminal nucleus (SpV)-specific
organoids. They further develop an organoid system that mimics the trigeminothalamic
projections between the SpV and the thalamus, a pivotal connection within sensory
circuits. The image depicts an information center that welcomes visitors embarking
on their journey to the hot air balloon scenic spot, symbolizing the essential role
of SpV as the information hub that transmits peripheral sensory information to the
thalamus and, subsequently, to higher brain structures where sensory processing occurs.
Image courtesy of the authors.",C,MAC_Bench/Cell/Cover/Cell Stem Cell/25_5.png,MAC_Bench/Cell/Cover/Cell Stem Cell/25_5.png,clip,25_5.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,vitg,6_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,groundtruth,31_3.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/24_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/24_1.png,vith,24_1.txt,val
JACS Au,2025_1,Which of the following options best describe the cover story?,"This experimental and theoretical study investigates design factors for the preparation of cadmium coordination polymers (CPs) containing fluorene and fluorenone cores as single-crystal optical waveguides. The CPs exhibit exceptional light propagation with one of the lowest optical losses for CPs and organic waveguides, providing insights for future design and optimization. The cover artwork was made by Daniele Mele. Some of the layers were generated by means of Google Gemini and Playground AI tools.",A,MAC_Bench/ACS/Cover/JACS Au/2025_1.png,MAC_Bench/ACS/Cover/JACS Au/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/JACS Au/2024_3.png,MAC_Bench/ACS/Cover/JACS Au/2024_3.png,vitg,2024_3.txt,MAC_Bench/ACS/Cover/JACS Au/2022_5.png,MAC_Bench/ACS/Cover/JACS Au/2022_5.png,clip,2022_5.txt,MAC_Bench/ACS/Cover/JACS Au/2023_4.png,MAC_Bench/ACS/Cover/JACS Au/2023_4.png,ave_3,2023_4.txt,train
ACS Materials Letters,2024_5,Which of the following options best describe the cover story?,-scale WSe2 flakes-based light-gated transistors. Different LGT behaviors at above- and below-threshold light-gating with pulse modulations demonstrate a great deal of potential use in the fields of neuromorphic computing and logic operations. View the article.,D,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_1.png,vith,2022_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_12.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_12.png,ave_2,2022_12.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2025_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_5.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_5.png,groundtruth,2024_5.txt,train
Acta Pharmacologica Sinica,45_5,Which of the following options best describe the cover story?,"Cover Credit: Reduction-activatable PROTAC prodrug nanoparticles for tumor-targeted protein degradation and anticancer therapy. The reduction-activatable PROTAC prodrug nanoparticles (NPs) were engineered by self-assembly of the PROTAC-conjugated amphiphilic diblock copolymer and further functionalized with a CRGDK ligand. The resulting PROTAC prodrug NPs can specifically target tumor cells and be efficiently internalized by recognizing neuropilin-1 (NRP-1), which is overexpressed on the surface of tumor cells. Remarkably, the PROTAC prodrug NPs efficiently degraded the protein targets BRD4 and CDK9 for inhibiting tumor growth in an mouse model of MDA-MB-231 triple-negative breast cancer. More importantly, the PROTAC prodrug NP can serve as a platform for co-delivering chemotherapeutic agents (e.g., doxorubicin, DOX) to perform combinatory cancer therapy. (Doi: 10.1038/s41401-024-01266-z). See the article in pages 1740–1751.",B,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_9.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_9.png,clip,43_9.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_5.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_5.png,groundtruth,45_5.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_6.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_6.png,vith,41_6.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_3.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_3.png,vitg,43_3.txt,train
Nature Sustainability,7_5,Which of the following options best describe the cover story?,"Sustainable sea urchin aquaculture
The process of obtaining sea urchin gonads, a high-demand culinary delicacy, involves the killing of the organism. Rakaj and colleagues present a sustainable no-kill sea urchin aquaculture method to produce an alternative market product of ‘caviar’ made of eggs produced by female batches.
See Rakaj et al.
Image and cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/Nature Sustainability/5_6.png,MAC_Bench/Nature/Cover/Nature Sustainability/5_6.png,vith,5_6.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_4.png,clip,7_4.txt,MAC_Bench/Nature/Cover/Nature Sustainability/3_10.png,MAC_Bench/Nature/Cover/Nature Sustainability/3_10.png,vitg,3_10.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_5.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_5.png,groundtruth,7_5.txt,train
Journal of Medicinal Chemistry,2024_3,Which of the following options best describe the cover story?,"RuBTB complex inhibits GSH metabolism, leading to immunogenic ferroptosis through GSH depletion, GPX4 inactivation, and so on. This subsequently reverses drug resistance by inhibiting GST activity. This is the first metal–arene anticancer complex that achieves efficient immunogenicity and satisfactory ferroptosis therapeutic effect for overcoming drug resistance in metal-based immunochemotherapy.  View the article.",D,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_19.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_19.png,vitg,2021_19.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_6.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_6.png,clip,2018_6.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_9.png,ave_0,2022_9.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_3.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_3.png,groundtruth,2024_3.txt,test
Journal of Medicinal Chemistry,2024_12,Which of the following options best describe the cover story?,"The front cover depicts original artwork by Carolyn Straub entitled “Reaching Out & Moving Forward"". The artwork represents the author's commitment to supporting her peers through the challenging journey of addiction recovery. The cover and accompanying Editorial are part of ACS Publications' Diversity and Inclusion Cover Art Series. View the article.",C,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_14.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_14.png,ave_2,2022_14.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_18.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_18.png,vitg,2024_18.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_12.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_16.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_16.png,clip,2021_16.txt,train
Nature Computational Science,4_12,Which of the following options best describe the cover story?,"Prediction of life outcomes
While the socio-demographic factors that play an important role in human lives are well understood, accurately predicting life outcomes has not been possible. In this issue, Sune Lehmann et al. introduce a machine learning approach, based on language processing techniques, that can predict different aspects of human lives. The proposed model — called ‘life2vec’ — establishes relationships between concepts, captured by an embedding space, that form the foundation for the predictions of life outcomes. The image depicts such an embedding space as it converges, where the white dots represent individuals and white lines represent how they move as the model is optimized. The shades of blue represent the density of points: the brighter the blue, the higher the density.
See Sune Lehmann et al.
Image: Germans Savcisens, Technical University of Copenhagen. Cover design: Alex Wing.",C,MAC_Bench/Nature/Cover/Nature Computational Science/4_4.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_4.png,vitg,4_4.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_7.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_7.png,vith,3_7.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_12.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_12.png,groundtruth,4_12.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_4.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_4.png,clip,3_4.txt,train
Nature Computational Science,4_7,Which of the following options best describe the cover story?,"Machine learning with nonlinear optical neural networks
Photonic computing offers many advantages over traditional digital computing, such as high parallelism and low energy consumption, yet current development has been mostly limited to linear operations. In this issue, Hao Wang et al. introduce a large-scale nonlinear photonic neural system based on disordered polycrystalline materials. The system generates both linear and nonlinear optical speckle features, forming a complex neural network that can be used for computing tasks. The authors demonstrate that this nonlinear system provides advantages over linear optical systems for various machine learning tasks, including image classification, regression, and graph classification. The cover image depicts the neural network formed by light scattering through a disordered medium.
See Hao Wang et al. and Tianyu Wang
Image: Hao Wang, Ecole Normale Supérieure and Tsinghua University. Cover design: Alex Wing",B,MAC_Bench/Nature/Cover/Nature Computational Science/3_9.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_7.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_7.png,groundtruth,4_7.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,ave_0,4_8.txt,MAC_Bench/Nature/Cover/Nature Computational Science/1_7.png,MAC_Bench/Nature/Cover/Nature Computational Science/1_7.png,clip,1_7.txt,train
Med,5_10,Which of the following options best describe the cover story?,"On the cover: While psilocybin-assisted psychotherapy (PAP) has shown promise in treating
depression, previous studies often excluded people with complex presentations. In
this issue of Med, Rosenblat et al. aimed to determine whether PAP could be feasible and beneficial in complex cases
of treatment-resistant depression as part of major depressive or bipolar II disorder
without psychosis or a substance use disorder, and those with baseline suicidality
and significant comorbidity. The authors found PAP to be safe and effective, and repeated
doses showed stronger benefits, suggesting further research is warranted to explore
this treatment option for harder-to-treat populations. Cover art from PM Images/Stone
via Getty Images.",B,MAC_Bench/Cell/Cover/Med/5_1.png,MAC_Bench/Cell/Cover/Med/5_1.png,vith,5_1.txt,MAC_Bench/Cell/Cover/Med/5_10.png,MAC_Bench/Cell/Cover/Med/5_10.png,groundtruth,5_10.txt,MAC_Bench/Cell/Cover/Med/4_2.png,MAC_Bench/Cell/Cover/Med/4_2.png,vitg,4_2.txt,MAC_Bench/Cell/Cover/Med/3_6.png,MAC_Bench/Cell/Cover/Med/3_6.png,clip,3_6.txt,train
NATURE REVIEWS CANCER,24_4,Which of the following options best describe the cover story?,"One circular RNA to rule them all, inspired by the Review on p597
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,vith,17_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/22_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/22_8.png,vitg,22_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/15_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/15_1.png,clip,15_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_4.png,groundtruth,24_4.txt,train
Journal of Chemical Education,2021_12,Which of the following options best describe the cover story?,"Modern chemistry programs must include the skills and techniques that enable their graduates to perform experiments safely. In response to a call for papers, scientists and educators from around the world have contributed articles to the Journal of Chemical Education's Special Issue on Chemical Safety Education: Methods, Culture, and Green Chemistry. The articles in the issue are broadly distributed among topics covering resources, green chemistry, safety culture, and pedagogy. This issue is a resource for ideas and discussion to encourage ""a new way to look at safety"", with a focus on assessing hazards, minimizing risk, and valuing a strong chemical safety culture. (Cover image courtesy of Jane E. Wissinger.)",C,MAC_Bench/ACS/Cover/Journal of Chemical Education/2012_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2012_2.png,clip,2012_2.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_10.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_10.png,ave_2,2016_10.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_12.png,groundtruth,2021_12.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2019_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2019_6.png,vitg,2019_6.txt,train
ACS Synthetic Biology,2024_12,Which of the following options best describe the cover story?,Shining the spotlight on gene editors: optically controlled Cas9 and Cre provide precise spatiotemporal control over gene editing. The review discusses the methods for engineering the optical control of these enzymes. Why light? Clinical benefits? Any limitations? The future? Read more to find out!,B,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_10.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_10.png,ave_2,2024_10.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_12.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,vitg,2015_2.txt,train
NATURE MATERIALS,23_7,Which of the following options best describe the cover story?,"Laser patterning of liquid-crystal elastomers
Lack of local phase patterning in liquid-crystal elastomers has hindered their broad implementation. The authors report a laser-induced dynamic crosslinking approach with allyl sulfide groups to achieve reconfigurable high-resolution patterning of multiple liquid crystalline phases in a single film.
See Choi et al.
Image: Seok Hwan Choi, Seoul National University. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_7.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_7.png,groundtruth,23_7.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/1_1.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/1_1.png,vitg,1_1.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/6_3.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/6_3.png,clip,6_3.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/6_4.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/6_4.png,vith,6_4.txt,test
Nature Reviews Electrical Engineering,1_4,Which of the following options best describe the cover story?,"Neuromorphic computers require both volatile and non-volatile memristors, along with a distinct property known as the ‘edge of chaos’. The cover shows the inventor of memristors, Leon O. Chua, and his nonlinear circuit theory. See Chua.
Cover design: Sam Whitham.",C,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,ave_3,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_4.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_4.png,groundtruth,1_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,clip,1_8.txt,train
Nature Aging,4_6,Which of the following options best describe the cover story?,"A cell atlas of worm longevity
In this issue, Shihong Max Gao et al. use a model organism that has been fundamental to our understanding of aging biology — Caenorhabditis elegans — and generate a comprehensive single-cell transcriptome atlas, profiling the cell-type-specific effects of aging and pro-longevity strategies. The cover image portrays two intertwined worms transitioning into swirling particles that stretch through time, assembling into a radial graph.
See Gao et al.
Image: Alps Xia. Cover design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Aging/4_6.png,MAC_Bench/Nature/Cover/Nature Aging/4_6.png,groundtruth,4_6.txt,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,clip,4_8.txt,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,vith,1_1.txt,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,vitg,1_4.txt,train
Nature Reviews Chemistry,8_7,Which of the following options best describe the cover story?,"Inserting atoms, ions or molecules between the pristine molecular layers of a 2D material can have a remarkable effect on its properties. Such fine tuning can be exploited to optimize the properties of these materials for applications in thermoelectrics, catalysis, and energy storage. The intercalation process can be studied in real-time by in situ imaging and vibrational spectroscopy techniques. The cover image illustrates a typical intercalation process of foreign species moving into the gaps between a layered material. See Yang et al.
Cover Image: Ruijie Yang, Zhiyuan Zeng. Cover design: Carl Conway",C,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,ave_1,7_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_10.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_10.png,clip,8_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_7.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_7.png,groundtruth,8_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/3_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/3_2.png,vitg,3_2.txt,train
ACS Nano,2025_1,Which of the following options best describe the cover story?,"Perovskite nanocrystals are assembled into superlattice structures inside lithographically fabricated hollow, three-dimensional transparent templates, enabling position and size control. When excited, the ordered quantum dots “cooperate” and collectively emit superfluorescent bursts of light.",B,MAC_Bench/ACS/Cover/ACS Nano/2022_1.png,MAC_Bench/ACS/Cover/ACS Nano/2022_1.png,clip,2022_1.txt,MAC_Bench/ACS/Cover/ACS Nano/2025_1.png,MAC_Bench/ACS/Cover/ACS Nano/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Nano/2022_7.png,MAC_Bench/ACS/Cover/ACS Nano/2022_7.png,vitg,2022_7.txt,MAC_Bench/ACS/Cover/ACS Nano/2022_4.png,MAC_Bench/ACS/Cover/ACS Nano/2022_4.png,vith,2022_4.txt,val
Joule,9_2,Which of the following options best describe the cover story?,"On the cover: In this cover image, Chen et al. present the conceptual design of a new electro-biodiesel platform that converts CO2 into biodiesel by integrating electrocatalysis and microbial bioconversion. The image
illustrates the integrated electro-biodiesel conversion process, where electrocatalytic
reactors convert CO2 into biocompatible C2 intermediates, which are then upgraded into biodiesel precursors
through efficient microbial fermentation. The process flow is shown by the bright
pathway. The transparent container at the center symbolizes the final diesel product.
The image highlights the advancement of an efficient and economic electro-biodiesel
route through the co-design of microbes and catalysts, opening new avenues for sustainable
CO2 conversion. Artist: Yu Zhang (@CYANTIFICA).",A,MAC_Bench/Cell/Cover/Joule/9_2.png,MAC_Bench/Cell/Cover/Joule/9_2.png,groundtruth,9_2.txt,MAC_Bench/Cell/Cover/Joule/4_2.png,MAC_Bench/Cell/Cover/Joule/4_2.png,clip,4_2.txt,MAC_Bench/Cell/Cover/Joule/6_11.png,MAC_Bench/Cell/Cover/Joule/6_11.png,vitg,6_11.txt,MAC_Bench/Cell/Cover/Joule/8_7.png,MAC_Bench/Cell/Cover/Joule/8_7.png,vith,8_7.txt,train
Trends in Pharmacological Sciences,45_12,Which of the following options best describe the cover story?,"Abnormal iron metabolism has long been regarded as a key metabolic
hallmark of cancer. Although the role of iron in tumor cells has been widely studied,
recent studies have uncovered the interplay of iron metabolism between tumor cells
and immune cells which may affect both innate and adaptive immune responses.
In a Review article of this issue, Zhang and colleagues present an overview of iron
homeostasis in cancer cells, discuss the current understanding of the regulatory
networks involved in iron metabolism within cancer cells, and explore how tumor iron
homeostasis affects or results from immunoregulatory therapy. Several key challenges
and potential therapeutic approaches for future investigations are also outlined.
The
cover image illustrates a transferrin-containing form of iron, which is the predominant
form under physiological conditions. Cover designed by Huai-Qiang Ju and Yan-Yu
Zhang via Cinema 4d and Photoshop.",B,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,clip,34_8.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_12.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_12.png,groundtruth,45_12.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_3.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_3.png,ave_2,40_3.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/39_1.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/39_1.png,vitg,39_1.txt,train
Immunity,57_6,Which of the following options best describe the cover story?,"On the cover: Cerebral interferonopathies such as Aicardi-Goutières’ Syndrome stem
from chronic activation of the type I interferon response within the central nervous
system, but the mediators of neurotoxicity are poorly defined. Viengkhou et al. identify the cerebral microvasculature as a critical transducer of interferon toxicity
within the brain. Deletion of the type I interferon receptor, IFNAR1, on endothelial
cells not only rescued cerebral vascular disease and restored blood-brain barrier
integrity but also prevented the development of diffuse brain disease, including neurodegeneration.
The devastating neurological changes mediated through cytokine-driven microvascular
disease are depicted as a leaf, full of tiny, delicate microvasculature networks reminiscent
of the human brain, changing from green to autumnal brown. Image by Ben Gartland,
Grant Foster, and Holly Philip.",B,MAC_Bench/Cell/Cover/Immunity/31_6.png,MAC_Bench/Cell/Cover/Immunity/31_6.png,vitg,31_6.txt,MAC_Bench/Cell/Cover/Immunity/57_6.png,MAC_Bench/Cell/Cover/Immunity/57_6.png,groundtruth,57_6.txt,MAC_Bench/Cell/Cover/Immunity/48_4.png,MAC_Bench/Cell/Cover/Immunity/48_4.png,vith,48_4.txt,MAC_Bench/Cell/Cover/Immunity/58_2.png,MAC_Bench/Cell/Cover/Immunity/58_2.png,clip,58_2.txt,train
Cell Genomics,4_7,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Huang et al. explore characteristic gut microbiota associated with phenotypes of the Chinese population
from 17 ethnic groups in China by metagenomics sequencing of 3,234 fecal samples.
The complexity and diversity of gut microbiota, akin to a veil of fog, were revealed.
The patterns within the 17 circles are symbolic patterns from 17 ethnic groups distributed
across various regions of China. The microbiota and genes at the center of the circles
reveal the species and genetic diversity of gut microbiota in the Chinese population.
Image credit: Qixiao Zhai.",D,MAC_Bench/Cell/Cover/Cell Genomics/5_1.png,MAC_Bench/Cell/Cover/Cell Genomics/5_1.png,ave_1,5_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,vitg,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_3.png,MAC_Bench/Cell/Cover/Cell Genomics/2_3.png,clip,2_3.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,groundtruth,4_7.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_6,Which of the following options best describe the cover story?,"The expanding repertoire of bile acids, inspired by the Perspective on p493
Cover design: Laura Marshall",A,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_6.png,groundtruth,21_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_8.png,clip,19_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_9.png,vith,19_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,vitg,20_4.txt,train
ACS Catalysis,2025_1,Which of the following options best describe the cover story?,Methane chlorination and the subsequent reduction by liquid reactive metal or solvated electrons are combined synergistically to convert methane into value-added chemicals during molten salt electrolysis.,B,MAC_Bench/ACS/Cover/ACS Catalysis/2023_5.png,MAC_Bench/ACS/Cover/ACS Catalysis/2023_5.png,vith,2023_5.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2025_1.png,MAC_Bench/ACS/Cover/ACS Catalysis/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2021_24.png,MAC_Bench/ACS/Cover/ACS Catalysis/2021_24.png,clip,2021_24.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2011_7.png,MAC_Bench/ACS/Cover/ACS Catalysis/2011_7.png,vitg,2011_7.txt,train
Nature Reviews Chemistry,8_6,Which of the following options best describe the cover story?,"Aromaticity is a controversial topic. Although widely used for the prediction and interpretation of chemical stability of both ground and excited states of molecules, no single index is known that unambiguously describes it. There has been a recent surge in reports using aromaticity to justify the stability of heavy elements’ clusters including actinides. The image shows a relief map of the induced current density — one of several state-of-the-art methods for examining aromaticity — applied to a tri-thorium cluster. The height of plots are proportional to the current intensity at each point. Recent developments in this field can transform our understanding of aromaticity, more than one and a half-century since this concept was introduced. For a review of state-of-the-art probes that have been used for assessing the aromaticity of heavy element clusters see Badri et al.
Image: Cina Foroutan-Nejad; Cover design: Carl Conway",B,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/2_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_6.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_6.png,groundtruth,8_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_12.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_12.png,vith,1_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,vitg,7_2.txt,train
Science,387_6732,Which of the following options best describe the cover story?,"COVER A breeding ruff male (Calidris pugnax) in alert posture scans the breeding area for mating opportunities at Liminka Bay, Finland. Ruff males deploy one of three mating tactics that differ in aggressive and courtship behaviors. Differences in aggression between tactics are tied to concentrations of circulating androgens, which are modulated by the actions of a single gene. See pages 358 and 406.
Photo: Jari Peltomäki/Finnature",A,MAC_Bench/Science/Cover/Science/387_6732.png,MAC_Bench/Science/Cover/Science/387_6732.png,groundtruth,387_6732.txt,MAC_Bench/Science/Cover/Science/363_6428.png,MAC_Bench/Science/Cover/Science/363_6428.png,ave_3,363_6428.txt,MAC_Bench/Science/Cover/Science/352_6287.png,MAC_Bench/Science/Cover/Science/352_6287.png,clip,352_6287.txt,MAC_Bench/Science/Cover/Science/362_6415.png,MAC_Bench/Science/Cover/Science/362_6415.png,vith,362_6415.txt,train
Immunity,57_9,Which of the following options best describe the cover story?,"On the cover: 2024 marks the 30th anniversary of Immunity! To celebrate this milestone with the immunology community, we hosted an open call
for cover submissions for our special anniversary issue and are grateful to have received
beautiful and creative submissions from across the globe! The winning design featured
on the cover of this anniversary issue was designed by Yun Hsuan Elena Lin, a PhD
candidate in the laboratory of Dr. John Chang at the University of Californa, San
Diego. In her illustration, immune cells are depicted as flowers flourishing from
vases in the shape of the number 30. The stalks of the flowers are comprised of DNA,
RNA, mitochondria, antibodies, blood vessels, lymphatics, neuronal and glial cells,
microbes, and more, highlighting advances in immunology research over the past decades.
Model organisms populate the image as well, recognizing their key contributions in
driving substantial advances in human immunology. The bouquet captures the diversity
of immunological research published by Immunity, painted over a backdrop of dawn that symbolizes the exciting discoveries to come. In this issue, we present a collection of review and perspective articles on innate
immunity with a focus on pattern recognition. Rather than recognizing unique aspects
of a pathogen, the innate immune system uses families of receptors that recognize
shared features of potential threats to the host. Likewise, sensing of endogenous
molecular patterns enables maintenance of health. Throughout this collection of articles,
we explore the latest understanding of how the innate immune system evolved to ensure
that the body responds appropriately to the myriad of microbes in the environment
while maintaining regulation of homeostatic functions, how these mechanisms can go
awry in disease, and the prospects for harnessing these insights into the development
of new therapies.",A,MAC_Bench/Cell/Cover/Immunity/57_9.png,MAC_Bench/Cell/Cover/Immunity/57_9.png,groundtruth,57_9.txt,MAC_Bench/Cell/Cover/Immunity/41_1.png,MAC_Bench/Cell/Cover/Immunity/41_1.png,vitg,41_1.txt,MAC_Bench/Cell/Cover/Immunity/41_3.png,MAC_Bench/Cell/Cover/Immunity/41_3.png,vith,41_3.txt,MAC_Bench/Cell/Cover/Immunity/51_5.png,MAC_Bench/Cell/Cover/Immunity/51_5.png,clip,51_5.txt,train
Cell Host&Microbe,32_8,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Host & Microbe, He et al. reveal the opposing functions between the condensed and non-condensed states of TaHRC-complexes
in wheat defense against Fusarium Head Blight (FHB). The dragon depicted on the cover
embodies this concept, signifying dual roles: it can either breathe rainwater (in
a non-phase separated state) to extinguish flames (representing FHB) on wheat spikes
for resistance or breathe fuel oil (in a phase-separated state) to exacerbate symptoms
for disease susceptibility. This study highlights the importance of biomolecular condensates
in host defense to crop/plant diseases.",A,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_8.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_8.png,groundtruth,32_8.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_12.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_12.png,vitg,31_12.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/5_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/5_3.png,clip,5_3.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/26_5.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/26_5.png,vith,26_5.txt,train
Nature Catalysis,8_1,Which of the following options best describe the cover story?,"Urea solidified
In their work, Xiaolin Zheng and colleagues couple hydrogen peroxide-selective oxygen electroreduction with precipitation of urea from urine resulting in wastewater purification and co-production of the solid nitrogen source percarbamide.
See Shi et al.
Image: Xinjian Shi, Henan University. Cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Catalysis/3_5.png,MAC_Bench/Nature/Cover/Nature Catalysis/3_5.png,clip,3_5.txt,MAC_Bench/Nature/Cover/Nature Catalysis/8_1.png,MAC_Bench/Nature/Cover/Nature Catalysis/8_1.png,groundtruth,8_1.txt,MAC_Bench/Nature/Cover/Nature Catalysis/4_5.png,MAC_Bench/Nature/Cover/Nature Catalysis/4_5.png,vith,4_5.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_3.png,vitg,7_3.txt,train
NATURE METHODS,21_12,Which of the following options best describe the cover story?,"Integrated protein structure modeling for cryo-EM
DeepMainmast builds structures of protein complexes from cryo-electron microscopy maps. It uses deep learning to identify key atom positions in the density, which are then connected to build fragment structures. Fragments are combined into a full structure, which is refined to atomic detail.
See Terashi et al.
Image: Pranav Deep Punuru, Purdue University. Cover Design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/NATURE METHODS/21_12.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_12.png,groundtruth,21_12.txt,MAC_Bench/Nature/Cover/NATURE METHODS/5_5.png,MAC_Bench/Nature/Cover/NATURE METHODS/5_5.png,vith,5_5.txt,MAC_Bench/Nature/Cover/NATURE METHODS/19_11.png,MAC_Bench/Nature/Cover/NATURE METHODS/19_11.png,vitg,19_11.txt,MAC_Bench/Nature/Cover/NATURE METHODS/17_11.png,MAC_Bench/Nature/Cover/NATURE METHODS/17_11.png,clip,17_11.txt,test
Trends in Biochemical Sciences,49_10,Which of the following options best describe the cover story?,"In this issue of Trends in Biochemical Sciences, two articles explore
related ideas of proteins being in the ‘neighborhood’ of their interaction partners
and
substrates. In their Review, Dr. Ciaran Seath and colleagues describe how proximity
labeling approaches can be used to explore protein-RNA and protein-ligand interactions,
as well as subcellular protein trafficking, and in their Opinion, Dr. Hyun-Woo Rhee
and co-authors describe spray-type post-translational modifications, a concept that
resembles proximity labeling methods. Cover image from GettyImages/soberve.",A,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_10.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_10.png,groundtruth,49_10.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_9.png,vith,45_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_7.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_7.png,clip,44_7.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/38_12.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/38_12.png,ave_1,38_12.txt,train
Biophysical Reports,4_4,Which of the following options best describe the cover story?,"On the cover: SpinFlux uses a spinning disk with pinholes in its illumination and
emission paths to sequentially illuminate regions in the sample during each measurement.
The resulting intensity-modulated emission signal is analyzed for each individual
pattern to localize emitters with up to 3.5-fold improved precision. The precision
improvement of SpinFlux is derived from retrieving the position of an emitter relative
to individual illumination patterns, which adds to existing point spread function
information from single-molecule localization microscopy. Kalisvaart et al. DOI: https://doi.org/10.1016/j.bpr.2024.100143",D,MAC_Bench/Cell/Cover/Biophysical Reports/1_1.png,MAC_Bench/Cell/Cover/Biophysical Reports/1_1.png,ave_3,1_1.txt,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,clip,4_3.txt,MAC_Bench/Cell/Cover/Biophysical Reports/4_2.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_2.png,ave_1,4_2.txt,MAC_Bench/Cell/Cover/Biophysical Reports/4_4.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_4.png,groundtruth,4_4.txt,train
Nature Reviews Chemistry,8_9,Which of the following options best describe the cover story?,"Upconversion enables the energy of two long wavelength photons to be combined, resulting in photoexcitation that would otherwise require a single short wavelength photon. Longer wavelength photons penetrate more deeply and so upconversion is especially useful for phototherapy and applications of photochemical reactions on a large scale. This process is shown on the cover where a green target absorbs two red incident rays and emits a single blue ray. See Huang et al.
Cover design: Carl Conway",C,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,clip,7_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_3.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_3.png,vith,6_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_9.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_9.png,groundtruth,8_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_4.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_4.png,vitg,7_4.txt,val
Nature Chemical Engineering,1_9,Which of the following options best describe the cover story?,"Electrifying separation processes
The recovery of valuable metals from waste sources remains challenging. Now, Xiao Su and colleagues demonstrate an electrochemical liquid–liquid extraction process that utilizes selective single-site binding of metal ions to a redox-active ferrocene in a continuously operating platform. This process achieved substantial up-concentration for gold and platinum group metals from several practical waste feedstocks.
See Cotty et al. and Schuur
Image: Stephen Cotty, University of Illinois Urbana-Champaign. Cover design: Thomas Phillips.",B,MAC_Bench/Nature/Cover/Nature Chemical Engineering/2_1.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/2_1.png,vitg,2_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,groundtruth,1_9.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,vith,1_12.txt,train
Precision Chemistry,2024_7,Which of the following options best describe the cover story?,"The integration of green hydrogen production and storage through electrocatalysis, enabling the direct conversion of CO2 and H2O into methanol or formic acid, and N2 or NOx with H2O into ammonia, holds great promise for streamlining the hydrogen economy.",D,MAC_Bench/ACS/Cover/Precision Chemistry/2023_9.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_9.png,vith,2023_9.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_8.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,vitg,2024_4.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_7.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_7.png,groundtruth,2024_7.txt,train
Nature Cancer,5_3,Which of the following options best describe the cover story?,"Mapping the microenvironment architecture of hepatocellular carcinoma
Spatial single-cell profiling of clinical hepatocellular carcinoma samples maps microenvironment architecture and heterogeneity, identifying functionally important immune cell populations.
See Qiu et al.
Image: Lei Chen, National Center for Liver Cancer and Eastern Hepatobiliary Surgery Hospital. Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Cancer/2_4.png,MAC_Bench/Nature/Cover/Nature Cancer/2_4.png,vitg,2_4.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_3.png,MAC_Bench/Nature/Cover/Nature Cancer/5_3.png,groundtruth,5_3.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_7.png,MAC_Bench/Nature/Cover/Nature Cancer/4_7.png,clip,4_7.txt,MAC_Bench/Nature/Cover/Nature Cancer/1_11.png,MAC_Bench/Nature/Cover/Nature Cancer/1_11.png,vith,1_11.txt,train
NATURE REVIEWS IMMUNOLOGY,25_1,Which of the following options best describe the cover story?,"Antibody-dependent Enhancement, inspired by the Review on p6.
Cover design: Simon Bradbrook",B,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/25_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/25_1.png,groundtruth,25_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,vitg,18_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_7.png,vith,19_7.txt,train
Molecular Therapy,33_1,Which of the following options best describe the cover story?,"On the cover: Chen et al. demonstrated that C-reactive protein (CRP) exacerbates renal inflammation in diabetic
kidney disease via a Smad3-NLRP3 inflammasome-dependent pathway. The image depicts
CRP binding to its receptor and triggering signaling to activate Smad3 in the cytoplasm.
Phosphorylated Smad3 translocates into the nucleus with other Smads. Following this,
Smad3 interacts with the promoter region of NLRP3, initiating NLRP3 expression. Image
credit: Haiyong Chen and Yifan Wang.",A,MAC_Bench/Cell/Cover/Molecular Therapy/33_1.png,MAC_Bench/Cell/Cover/Molecular Therapy/33_1.png,groundtruth,33_1.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_17.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_17.png,clip,31_17.txt,MAC_Bench/Cell/Cover/Molecular Therapy/26_5.png,MAC_Bench/Cell/Cover/Molecular Therapy/26_5.png,vith,26_5.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_15.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_15.png,vitg,31_15.txt,val
Nature Microbiology,10_2,Which of the following options best describe the cover story?,"Microbiome predicts potato growth potential
Pictured is an aerial image from a drone-mounted camera of a potato trial field. In this issue, Song et al. show that time-resolved drone imaging of potato crop development and seed tuber microbiome data can be used to predict potato vigour, or growth potential.
See Song et al.
Image: Elisa Atza, Technical University Delft. Cover design: Laoise Mac Gabhann",C,MAC_Bench/Nature/Cover/Nature Microbiology/3_4.png,MAC_Bench/Nature/Cover/Nature Microbiology/3_4.png,clip,3_4.txt,MAC_Bench/Nature/Cover/Nature Microbiology/6_4.png,MAC_Bench/Nature/Cover/Nature Microbiology/6_4.png,vitg,6_4.txt,MAC_Bench/Nature/Cover/Nature Microbiology/10_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/10_2.png,groundtruth,10_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_3.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_3.png,vith,9_3.txt,train
NATURE METHODS,21_1,Which of the following options best describe the cover story?,"Method of the Year 2024: spatial proteomics
Spatial proteomics is our pick for Method of the Year 2024. The cover illustrates cellular neighborhoods within tumors, revealing the diverse and complex microenvironments that shape tumor biology.
See Editorial
Image: Elham Karimi and Simon Milette, Walsh and Quail Labs, Rosalind and Morris Goodman Cancer Institute. Cover design: Thomas Phillips",A,MAC_Bench/Nature/Cover/NATURE METHODS/21_1.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_1.png,groundtruth,21_1.txt,MAC_Bench/Nature/Cover/NATURE METHODS/18_12.png,MAC_Bench/Nature/Cover/NATURE METHODS/18_12.png,clip,18_12.txt,MAC_Bench/Nature/Cover/NATURE METHODS/18_8.png,MAC_Bench/Nature/Cover/NATURE METHODS/18_8.png,ave_2,18_8.txt,MAC_Bench/Nature/Cover/NATURE METHODS/17_12.png,MAC_Bench/Nature/Cover/NATURE METHODS/17_12.png,ave_1,17_12.txt,train
NATURE REVIEWS GENETICS,25_12,Which of the following options best describe the cover story?,"Inspired by the Reviews on p8 and p61
Cover design: Patrick Morgan",A,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_12.png,groundtruth,25_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/16_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/16_8.png,vitg,16_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_9.png,clip,15_9.txt,train
innovation,5_6,Which of the following options best describe the cover story?,"On the cover: MXenes, regarded as the “wonder” of two-dimensional materials, exhibit
extraordinary physicochemical properties and show great promise for a wide range of
applications, including energy storage, electromagnetic interference shielding, biomedicine,
printing circuits, and more. A transformative gas synthesis route eliminates the expensive
precursors and enables direct fabrication of pure-phase and low-defect MXene, tackling
the longstanding challenge of synthesis of high-quality MXenes by the conventional
liquid phase etching route. Compared to the costly and winding liquid-phase etching
route, the gas-phase synthesis pathway is more economical and efficient, accelerating
the transition of MXenes from laboratory to industrial applications.",B,MAC_Bench/Cell/Cover/innovation/2_4.png,MAC_Bench/Cell/Cover/innovation/2_4.png,clip,2_4.txt,MAC_Bench/Cell/Cover/innovation/5_6.png,MAC_Bench/Cell/Cover/innovation/5_6.png,groundtruth,5_6.txt,MAC_Bench/Cell/Cover/innovation/3_5.png,MAC_Bench/Cell/Cover/innovation/3_5.png,ave_1,3_5.txt,MAC_Bench/Cell/Cover/innovation/3_1.png,MAC_Bench/Cell/Cover/innovation/3_1.png,ave_2,3_1.txt,train
Molecular Pharmaceutics,2025_2,Which of the following options best describe the cover story?,"This figure shows an amorphous solid dispersion of indometacin (glowing blue) within a matrix of polyvinylpyrrolidone (PVP). The perspective highlights the drug’s chemical environment, with the polymer structure intricately rendered, offering insight into the interactions within the dispersion. No molecules were removed from this real-world simulation data. View the article.",D,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_1.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_1.png,ave_1,2021_1.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,vitg,2022_8.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_5.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_5.png,clip,2022_5.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2025_2.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2025_2.png,groundtruth,2025_2.txt,test
ACS Nanoscience Au,2024_5,Which of the following options best describe the cover story?,"The cover is a depiction of a newer variant of SARS-CoV-2 virus engaging with a mammalian cell via the ACE-2 receptor, while antibodies neutralize previous variants in the background to differing extents. In the ongoing battle against COVID-19, the intricate dance between virus mutation and host defenses continues, with immunity yet to be guaranteed.",C,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_3.png,ave_1,2024_3.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_5.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_6.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_6.png,clip,2022_6.txt,train
Trends in Parasitology,40_10,Which of the following options best describe the cover story?,"The cover illustrates a famous self portrait of Frida Kahlo that depicts
the close relation between humans and animals (domestics and wildlife) in a tropical
environment, typical of many zoonotic dirofilariasis infections. The parasite and
its vector
(Dirofilaria and the mosquito) are also part of this intricate interface. In this issue of Trends in
   Parasitology, Perles et al. review data concerning dirofilariasis in humans, especially wildlife
associated Dirofilaria species that are less often reported as causative agents of human
dirofilariasis, including D. striata, D. tenuis, D. ursi, D. spectans and D. magnilarvata. The authors advocate the importance of combined morphological and genomic approaches
to
providing unequivocal evidence for their zoonotic potential and pathogenicity. Image
credit: Sofia Otranto and Jairo Mendoza-Roldan.",C,MAC_Bench/Cell/Cover/Trends in Parasitology/28_1.png,MAC_Bench/Cell/Cover/Trends in Parasitology/28_1.png,clip,28_1.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/32_7.png,MAC_Bench/Cell/Cover/Trends in Parasitology/32_7.png,ave_1,32_7.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_10.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_10.png,groundtruth,40_10.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/37_5.png,MAC_Bench/Cell/Cover/Trends in Parasitology/37_5.png,vitg,37_5.txt,train
Nature Reviews Materials,9_1,Which of the following options best describe the cover story?,"High-entropy materials are primarily known for their mechanical strength and high toughness. However, they can also be used as a platform for multifunctional material design, in which several, even conflicting, properties can be reconciled because of the compositional tolerance inherent in the high-entropy concept: these include electronic, magnetic, mechanical, catalytic, thermal expansion and hydrogen storage properties. The cover shows 3D atom probe tomography data from a chemically complex Ti Mo based alloy. See Han L.et al.
Cover image: Dierk Raabe. Cover design: David Johnston",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/6_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/6_2.png,vitg,6_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_8.png,vith,4_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_11.png,clip,5_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_1.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_1.png,groundtruth,9_1.txt,train
Science Immunology,9_94,Which of the following options best describe the cover story?,"ONLINE COVER Cultivating Memory B Cell Responses to a Plant-Based Vaccine. CoVLP (coronavirus virus-like particle) is a promising COVID-19 vaccine produced in the weed Nicotiana benthamiana. A squalene-based adjuvant, AS03, can enhance immune responses to CoVLP vaccination, but how AS03 affects memory B cell responses to CoVLP is unknown. Grigoryan et al. studied immune responses in healthy individuals who received two doses of CoVLP with or without AS03. They found that AS03 promoted the progressive maturation of memory B cell responses over time, leading to enhanced neutralization of SARS-CoV-2 and increased memory B cell breadth. This month’s cover illustration depicts a syringe containing a plant-based SARS-CoV-2 vaccine. Credit: N. Jessup/Science Immunology (syringe: C. Horz/Alamy Stock Vector)",B,MAC_Bench/Science/Cover/Science Immunology/8_86.png,MAC_Bench/Science/Cover/Science Immunology/8_86.png,vith,8_86.txt,MAC_Bench/Science/Cover/Science Immunology/9_94.png,MAC_Bench/Science/Cover/Science Immunology/9_94.png,groundtruth,9_94.txt,MAC_Bench/Science/Cover/Science Immunology/3_23.png,MAC_Bench/Science/Cover/Science Immunology/3_23.png,clip,3_23.txt,MAC_Bench/Science/Cover/Science Immunology/5_47.png,MAC_Bench/Science/Cover/Science Immunology/5_47.png,vitg,5_47.txt,train
Chemical Research in Toxicology,2025_2,Which of the following options best describe the cover story?,"Environmental stability determines the degradation of metal–organic frameworks. The unstable Zn-BDC released Zn2+ and induced cytotoxicity to nitrogen-fixing bacteria Azotobacter vinelandii. Zn-BDC directly disturbed the ribosome pathway, and lowered the expression level of nitrogen fixation nif cluster genes.",C,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_1.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_8.png,clip,2012_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2025_2.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_3.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_3.png,vitg,2023_3.txt,train
ACS Applied Materials & Interfaces,2025_9,Which of the following options best describe the cover story?,"Using two-photon phosphorescence lifetime imaging microscopy, the ReI-probe non-invasively tracks wound healing by monitoring collagen regeneration and tissue oxygenation. Bound to collagen, it serves as a density sensor, while unbound probes measure oxygen levels through phosphorescence lifetime changes, enabling simultaneous assessment of the oxygen concentration and collagen content. View the article.",A,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_9.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_9.png,groundtruth,2025_9.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_7.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_7.png,clip,2025_7.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_37.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_37.png,ave_1,2024_37.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_40.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_40.png,vitg,2024_40.txt,train
Cell Genomics,4_2,Which of the following options best describe the cover story?,"On the cover: The cover represents a visual metaphor for the pipeline developed by
Saez Atienzar et al. in this issue of Cell Genomics, which uses large-scale genomics and transcriptomics to identify promising drugs
for C9orf72-related diseases, such as amyotrophic lateral sclerosis and frontotemporal dementia.
The front of the image features a selected drug, symbolizing the successful repurposing
of a therapeutic candidate (acamprosate). In contrast, other drugs are depicted as
being rejected or left behind, representing those deemed ineffective by our screening
process. This captures the essence of our proposed repurposing strategy: a rigorous,
data-driven approach to narrow down effective treatments from a broad pool of candidates.",C,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,clip,3_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_8.png,MAC_Bench/Cell/Cover/Cell Genomics/4_8.png,ave_0,4_8.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_2.png,MAC_Bench/Cell/Cover/Cell Genomics/4_2.png,groundtruth,4_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,vitg,5_2.txt,train
Cell Systems,15_6,Which of the following options best describe the cover story?,"On the cover: An array of human kidney organoids patterned with precise control over
starting nephron progenitor number. Staining for podocytes (NPHS1, yellow), proximal
tubules (LTL, cyan), and distal tubules (ECAD, bright pink) demonstrates the capability
for more targeted self-organization of organoid tissues and structures. In this issue
of Cell Systems, Porter et al. use a DNA-based cell patterning technology to demonstrate that precise control over
the initial numbers and ratios of epithelial progenitors modulates tissue composition
and morphology in a human kidney organoid model. Image credit: the authors.",D,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,ave_1,1_2.txt,MAC_Bench/Cell/Cover/Cell Systems/2_5.png,MAC_Bench/Cell/Cover/Cell Systems/2_5.png,ave_2,2_5.txt,MAC_Bench/Cell/Cover/Cell Systems/6_4.png,MAC_Bench/Cell/Cover/Cell Systems/6_4.png,clip,6_4.txt,MAC_Bench/Cell/Cover/Cell Systems/15_6.png,MAC_Bench/Cell/Cover/Cell Systems/15_6.png,groundtruth,15_6.txt,train
ACS Chemical Biology,2024_4,Which of the following options best describe the cover story?,"Protein abnormal S-palmitoylation is associated with a variety of diseases, but rare effective S-palmitoylation inhibitors have been reported. Targeting the PATs and",D,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_2.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_2.png,clip,2019_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2018_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2018_9.png,vitg,2018_9.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2016_5.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2016_5.png,ave_1,2016_5.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_4.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_4.png,groundtruth,2024_4.txt,train
NATURE REVIEWS NEUROSCIENCE,25_4,Which of the following options best describe the cover story?,"‘Learning across timescales’, inspired by the Review on p597.
Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_8.png,vitg,24_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_10.png,clip,24_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/19_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/19_10.png,vith,19_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_4.png,groundtruth,25_4.txt,train
Trends in Pharmacological Sciences,45_5,Which of the following options best describe the cover story?,"Bruton’s tyrosine kinase (BTK) inhibitors play a pivotal role in the
treatment of many B cell lymphomas. In this issue, Cool et al. provide a comprehensive
review presenting the past, present, and future of BTK inhibitors transforming the
treatment landscape of these diseases, such as chronic lymphocytic leukemia. The
cover illustrates this relentless innovation, with both translational laboratory and
clinical
research that led to the development of several novel BTK inhibitors, with subsequent
agents addressing the safety and resistance mechanisms of previous therapies. The
cover image was designed by Aila Jiang, and hand-drawn using Paint Tool Sai.",A,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_5.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_5.png,groundtruth,45_5.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_2.png,vitg,42_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,vith,34_8.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/44_7.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/44_7.png,clip,44_7.txt,train
Molecular Plant,18_3,Which of the following options best describe the cover story?,"On the cover: In this issue, Lei et al. explore the regulatory role of the long non-coding RNA
ALEX1 in enhancing the resistance of rice to bacterial infections through its interaction
with ARF3. Under normal conditions, ALEX1 is expressed at low levels, allowing ARF3 to aggregate into solid-like condensates,
representing an inactive or “non-functional” phase state. However, upon pathogen infection,
ALEX1 expression is upregulated, and it binds directly to the MR domain of ARF3, facilitating
its dimerization and preventing condensate formation. This transition maintains an
active ARF3 pool, which represses the transcription of JAZ13 and activates the jasmonic acid (JA) pathway, thereby enhancing plant defense. The
cover image depicts the dynamic interplay between ALEX1 and ARF3 in modulating rice immunity. ALEX1 is portrayed as a bow, symbolizing its role in activating ARF3, represented by arrows.
The quiver on the angel's back, filled with blue arrows, signifies ARF3 in its non-functional
condensate state. This visual metaphor highlights how ALEX1 enables ARF3 transition to a functional state, orchestrating plant defense responses
against bacterial pathogens. Image by Meng-Qi Lei, Yang Yu and Yue-Qin Chen.",C,MAC_Bench/Cell/Cover/Molecular Plant/15_9.png,MAC_Bench/Cell/Cover/Molecular Plant/15_9.png,vith,15_9.txt,MAC_Bench/Cell/Cover/Molecular Plant/16_5.png,MAC_Bench/Cell/Cover/Molecular Plant/16_5.png,clip,16_5.txt,MAC_Bench/Cell/Cover/Molecular Plant/18_3.png,MAC_Bench/Cell/Cover/Molecular Plant/18_3.png,groundtruth,18_3.txt,MAC_Bench/Cell/Cover/Molecular Plant/14_3.png,MAC_Bench/Cell/Cover/Molecular Plant/14_3.png,vitg,14_3.txt,val
Nature Biomedical Engineering,8_8,Which of the following options best describe the cover story?,"Supramolecular bispecific T cell engagers with controllable disassembly
This issue highlights advances in the design of bispecific T cell engagers, chimeric antigen receptor T cells, mineralized bacteria and other cellular as well as molecular immunotherapies for the modulation of the activity of the immune system against cancers and other inflammatory conditions.
The cover illustrates the small-molecule-mediated control of the antitumour activity of a supramolecular bispecific T cell engager through its disassembly.
See Gong et al.
Image: Ningqiang Gong. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_9.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_9.png,vith,8_9.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_8.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_8.png,groundtruth,8_8.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_12.png,vitg,7_12.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_2.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_2.png,clip,5_2.txt,val
Nature Reviews Neurology,20_1,Which of the following options best describe the cover story?,"The digital clinic, inspired by the Perspective on p738
Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_5.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_5.png,vitg,19_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_1.png,groundtruth,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_5.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_5.png,ave_3,20_5.txt,train
Trends in Genetics,40_8,Which of the following options best describe the cover story?,"Bdelloid rotifers are microscopic filter-feeding animals that live in
freshwater habitats worldwide. In this issue, Wilson et al. discuss how recombination
interlinks with three strange features of bdelloids: high levels of horizontal gene
acquisition, stress-tolerance, and an apparent lack of males. This individual of the
species Rotaria macrura is about 500 μm long, is attached to floating debris from a
pond in Hattingen, Germany, and was collected and photographed by Michael Plewka.
It is feeding using the ciliated discs (corona) on either side of its red eye-spots.",B,MAC_Bench/Cell/Cover/Trends in Genetics/28_5.png,MAC_Bench/Cell/Cover/Trends in Genetics/28_5.png,clip,28_5.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_8.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_8.png,groundtruth,40_8.txt,MAC_Bench/Cell/Cover/Trends in Genetics/32_4.png,MAC_Bench/Cell/Cover/Trends in Genetics/32_4.png,ave_2,32_4.txt,MAC_Bench/Cell/Cover/Trends in Genetics/34_12.png,MAC_Bench/Cell/Cover/Trends in Genetics/34_12.png,vith,34_12.txt,test
One Earth,7_6,Which of the following options best describe the cover story?,"On the cover: Land is a finite resource, yet as the human population grows our demands
on land are ever increasing. Parcels of land have undergone multiple transformations,
and unsustainable land management practices have negatively impacted both people and
planet. Cover: Development plans on rural valley. Rupert King, Getty.",B,MAC_Bench/Cell/Cover/One Earth/2_2.png,MAC_Bench/Cell/Cover/One Earth/2_2.png,clip,2_2.txt,MAC_Bench/Cell/Cover/One Earth/7_6.png,MAC_Bench/Cell/Cover/One Earth/7_6.png,groundtruth,7_6.txt,MAC_Bench/Cell/Cover/One Earth/2_4.png,MAC_Bench/Cell/Cover/One Earth/2_4.png,ave_3,2_4.txt,MAC_Bench/Cell/Cover/One Earth/5_8.png,MAC_Bench/Cell/Cover/One Earth/5_8.png,vitg,5_8.txt,val
NATURE REVIEWS CANCER,24_7,Which of the following options best describe the cover story?,"Antibody libraries, inspired by the Review on p399.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_9.png,vitg,23_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,vith,17_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_2.png,clip,13_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_7.png,groundtruth,24_7.txt,train
Nature Reviews Bioengineering,3_1,Which of the following options best describe the cover story?,"Stem cell-based embryo models can recapitulate symmetry breaking, pattern formation and tissue morphogenesis during early development. To control and guide their in vivo-like cellular organization and architecture, bioengineering approaches can be applied, including biomaterials, additive manufacturing, microphysiological models and synthetic biology. See Xufeng Xue et al.
Cover image: Simon Bradbrook",D,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_2.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_7.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_7.png,vith,2_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,groundtruth,3_1.txt,train
Molecular Therapy,32_1,Which of the following options best describe the cover story?,"On the cover: Damodar et al. demonstrated that RLBP1 encodes two CRALBP isoforms that are differentially expressed in human and murine
retinal tissues: two isoforms in retinal pigment epithelium and one isoform in Müller
glial cells. The image shows 3D isosurface rendering (Imaris) of a 250-day-old retinal
organoid labeled for CRALBP (multicolor object ID) in Müller glial cells. The Müller
cells span the outer nuclear layer (in blue), with their end feet forming the outer
limiting membrane that surrounds the organoid. Image credit: Hassan Boukhaddaoui and
Nejla Erkilic.",A,MAC_Bench/Cell/Cover/Molecular Therapy/32_1.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_1.png,groundtruth,32_1.txt,MAC_Bench/Cell/Cover/Molecular Therapy/28_3.png,MAC_Bench/Cell/Cover/Molecular Therapy/28_3.png,clip,28_3.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_7.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_7.png,vitg,32_7.txt,MAC_Bench/Cell/Cover/Molecular Therapy/26_5.png,MAC_Bench/Cell/Cover/Molecular Therapy/26_5.png,vith,26_5.txt,train
Nature Chemistry,16_10,Which of the following options best describe the cover story?,"Caught in a trap
Sulfate-binding proteins — which capture sulfate from water using hydrogen bonds from charge-neutral motifs — serve as key inspiration in anion receptor chemistry, but synthetic systems showing similar selectivity have so far been elusive. Xin Wu, Evelyne Deplazes and colleagues have now made a neutral molecular cage that binds sulfate in water using 12 hydrogen atoms, as depicted artistically on the cover. The background shows an empty cage and an unbound sulfate.
See Jing et al.
Image: Bolun Chen, Senling Culture Co., Ltd. Cover Design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/Nature Chemistry/16_10.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_10.png,groundtruth,16_10.txt,MAC_Bench/Nature/Cover/Nature Chemistry/13_4.png,MAC_Bench/Nature/Cover/Nature Chemistry/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/Nature Chemistry/12_4.png,MAC_Bench/Nature/Cover/Nature Chemistry/12_4.png,vith,12_4.txt,MAC_Bench/Nature/Cover/Nature Chemistry/5_10.png,MAC_Bench/Nature/Cover/Nature Chemistry/5_10.png,vitg,5_10.txt,train
Industrial & Engineering Chemistry Research,2024_41,Which of the following options best describe the cover story?,"This compilation from renowned scientists endeavors to pay tribute to the distinguished career of Professor Dmitri Murzin, acknowledging his profound impact on the area of catalysis and chemical technology through both his scholarly endeavors and educational initiatives. Professor Murzin's legacy is celebrated for its significant contributions to advancing scientific knowledge and fostering the growth of future generations of researchers in these pivotal fields.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_47.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_47.png,ave_2,2021_47.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_41.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_41.png,groundtruth,2024_41.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_4.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_4.png,ave_3,2021_4.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_39.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_39.png,clip,2024_39.txt,test
Trends in Chemistry,6_7,Which of the following options best describe the cover story?,"Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for part 1 showcases the 'great career race' for early-career
scientists today, with key milestones towards promotion and the many paths that can
be taken on the road to success. Each running at their own pace, the authors in this
issue are all aiming to innovate with an impact, solve real-world problems and become
inspiring leaders themselves. Artwork credit: Phillip Krzeminski",C,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,ave_3,6_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,clip,6_8.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,groundtruth,6_7.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,vith,6_6.txt,val
NATURE ENERGY,9_3,Which of the following options best describe the cover story?,"Support for renewable energy infrastructure
Political will is needed for large-scale renewable energy infrastructure projects, which must also reflect constituents’ preferences. Caggiano et al. identify limited differences in partisan support for such projects in Pennsylvania, however elected officials underestimate support for renewables and the importance of job creation for constituents.
See Caggiano et al. and Policy Brief
Image: Michael Galinsky. Cover design: Thomas Phillips.",C,MAC_Bench/Nature/Cover/NATURE ENERGY/1_7.png,MAC_Bench/Nature/Cover/NATURE ENERGY/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/3_3.png,MAC_Bench/Nature/Cover/NATURE ENERGY/3_3.png,ave_1,3_3.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_3.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_3.png,groundtruth,9_3.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/1_3.png,MAC_Bench/Nature/Cover/NATURE ENERGY/1_3.png,vitg,1_3.txt,train
Nature Microbiology,9_4,Which of the following options best describe the cover story?,"Fusarium goes bananas
This image shows leaf yellowing on a Cavendish banana plant in northern Mozambique. The plant was infected by Fusarium oxysporum f. sp. cubense tropical race 4 (TR4), a soil-borne fungus, that affects a range of banana varieties. Once present in a banana field, the fungus cannot be eradicated, making future production of Cavendish bananas almost impossible. In this issue, Zhang et al. show that all Cavendish banana-infecting race 4 strains share a single origin, and that TR4 accessory genes are enriched for virulence and mitochondrion-related functions. The authors also discovered that the fungal nitric oxide biosynthesis pathway is induced upon banana plant infection, suggesting that nitric oxide could be used as a target for disease management.
See Zhang et al.
Image: Altus Viljoen. Cover design: Debbie Maizels",A,MAC_Bench/Nature/Cover/Nature Microbiology/9_4.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_4.png,groundtruth,9_4.txt,MAC_Bench/Nature/Cover/Nature Microbiology/7_7.png,MAC_Bench/Nature/Cover/Nature Microbiology/7_7.png,ave_3,7_7.txt,MAC_Bench/Nature/Cover/Nature Microbiology/8_5.png,MAC_Bench/Nature/Cover/Nature Microbiology/8_5.png,clip,8_5.txt,MAC_Bench/Nature/Cover/Nature Microbiology/10_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/10_2.png,vith,10_2.txt,val
Nature Photonics,19_1,Which of the following options best describe the cover story?,"Magneto-optic exceptional points
An artistic illustration of a highly sensitive magnetic field sensor that makes use of magneto-optic exceptional points. The apparatus consists of a Fabry–Perot cavity containing a magneto-optic crystal of terbium gallium garnet and a liquid-crystal cell. Frequency splitting of the modes at the exceptional point in the cavity provides a highly sensitive measurement of magnetic field strength.
See Ruan et al.
Image: Yanan Zhang, Senling (Shandong) Culture Transmission Co., LTD. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Photonics/19_2.png,MAC_Bench/Nature/Cover/Nature Photonics/19_2.png,vitg,19_2.txt,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,ave_2,16_12.txt,MAC_Bench/Nature/Cover/Nature Photonics/1_2.png,MAC_Bench/Nature/Cover/Nature Photonics/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Photonics/19_1.png,MAC_Bench/Nature/Cover/Nature Photonics/19_1.png,groundtruth,19_1.txt,train
NATURE REVIEWS NEUROSCIENCE,26_1,Which of the following options best describe the cover story?,"‘Structural similarity networks’, inspired by the Review on p42
Cover design: Jennie Vallis",A,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/26_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/26_1.png,groundtruth,26_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/23_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/23_5.png,vith,23_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,clip,15_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,vitg,25_3.txt,train
Trends in Plant Science,30_1,Which of the following options best describe the cover story?,"To resist biotic attacks, plants have evolved a sophisticated immune
system with cell-surface immune receptors acting as the first line of the defense
machinery. These receptors are either receptor-like kinases (RLKs) or receptor-like
proteins (RLPs). RLPs lack a cytoplasmic kinase domain for downstream immune
signalling, and leucine-rich repeat (LRR)-containing RLPs constitutively associate
with
the RLK SOBIR1. The RLP/SOBIR1 complex was proposed to be the bimolecular
equivalent of genuine RLK receptors, but it appears that their molecular mechanisms
of
immunity show some striking differences. Wen R.H. Huang and Matthieu H.A.J. Joosten
summarize these differences, focussing on how these receptors recruit the BAK1 co-receptor
and elaborating on the negative crosstalk occurring between the two signalling
networks. The mirror symbolizes the complex relationship between RLPs and RLKs,
illustrating their structural similarities yet functional differences in immune responses.
Image credit: Alison Zou.",C,MAC_Bench/Cell/Cover/Trends in Plant Science/24_6.png,MAC_Bench/Cell/Cover/Trends in Plant Science/24_6.png,clip,24_6.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/30_2.png,MAC_Bench/Cell/Cover/Trends in Plant Science/30_2.png,vith,30_2.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/30_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/30_1.png,groundtruth,30_1.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/27_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/27_1.png,vitg,27_1.txt,train
JACS Au,2024_10,Which of the following options best describe the cover story?,"The membrane-bound phospholipase A1 from Pseudomonas aeruginosa is a potential drug target. PlaF remodels membrane glycerophospholipids, influencing virulence-associated signaling. Medium-chain free fatty acids, products of PlaF action, inhibit its activity. Molecular simulations and free energy computations uncover how fatty acids control PlaF. For this image, an author-made hand drawing was refined with GPT-4.",A,MAC_Bench/ACS/Cover/JACS Au/2024_10.png,MAC_Bench/ACS/Cover/JACS Au/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/JACS Au/2022_12.png,MAC_Bench/ACS/Cover/JACS Au/2022_12.png,vith,2022_12.txt,MAC_Bench/ACS/Cover/JACS Au/2023_5.png,MAC_Bench/ACS/Cover/JACS Au/2023_5.png,clip,2023_5.txt,MAC_Bench/ACS/Cover/JACS Au/2022_3.png,MAC_Bench/ACS/Cover/JACS Au/2022_3.png,ave_3,2022_3.txt,val
ACS ES&T Engineering,2024_1,Which of the following options best describe the cover story?,An indispensable synergy was found between C=C and C=O sites in biochar for peroxomonosulfate activation and sulfamethoxazole degradation. The,A,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_1.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_3.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_3.png,clip,2023_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_7.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_7.png,vith,2022_7.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_7.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_7.png,vitg,2024_7.txt,train
Nature Cardiovascular Research,3_1,Which of the following options best describe the cover story?,"How the glutamine-to-glutamate ratio influences atherosclerosis
Murcy et al. show that increasing the plasma ratio of glutamine to glutamate in a mouse model of atherosclerosis can distally reprogram transcriptional and post-transcriptional remodeling of the aorta by GLS2-dependent hepatic glutaminolysis.
See Murcy et al.
Image: Aude Laurent (Ododo) - Motion design / Art direction / Video editing / illustration *FREELANCE*. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/4_1.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/4_1.png,vitg,4_1.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_1.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_1.png,groundtruth,3_1.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png,clip,3_8.txt,val
ACS Applied Materials & Interfaces,2025_7,Which of the following options best describe the cover story?,"Using two-photon phosphorescence lifetime imaging microscopy, the ReI-probe non-invasively tracks wound healing by monitoring collagen regeneration and tissue oxygenation. Bound to collagen, it serves as a density sensor, while unbound probes measure oxygen levels through phosphorescence lifetime changes, enabling simultaneous assessment of the oxygen concentration and collagen content.",D,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_37.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_37.png,ave_1,2024_37.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_8.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_8.png,clip,2025_8.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_40.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_40.png,vitg,2024_40.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_7.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_7.png,groundtruth,2025_7.txt,train
Nature Chemistry,16_4,Which of the following options best describe the cover story?,"Topological transformations of DNA origami
Biological systems often use topological transformations to control the flow of molecular information, but constructing artificial structures capable of such controlled structural changes is challenging. Now, Chunhai Fan, Hao Pei and co-workers have developed DNA origami systems that undergo global conformational changes upon topological operations involving ‘glue–cut’ processes. The cover depicts three differently shaped DNA nanostructures — showcasing variations in size, shape and topological properties — with a mechanical operating arm representing the topological operations.
See Ji et al.
Image: Xiewei Xiong, East China Normal University. Cover design: Laoise Mac Gabhann",B,MAC_Bench/Nature/Cover/Nature Chemistry/5_9.png,MAC_Bench/Nature/Cover/Nature Chemistry/5_9.png,vitg,5_9.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_4.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_4.png,groundtruth,16_4.txt,MAC_Bench/Nature/Cover/Nature Chemistry/7_1.png,MAC_Bench/Nature/Cover/Nature Chemistry/7_1.png,ave_1,7_1.txt,MAC_Bench/Nature/Cover/Nature Chemistry/11_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/11_6.png,clip,11_6.txt,test
ACS Earth and Space Chemistry,2024_11,Which of the following options best describe the cover story?,SEM image of the ferrihydrite added to the radioiodine-contaminated sediment samples in the column sorption and transport experiments. The SEM image was taken by Odeta Qafoku (PNNL).,D,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_9.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_9.png,ave_2,2024_9.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_4.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,ave_3,2024_10.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_11.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_11.png,groundtruth,2024_11.txt,test
Current Biology,34_3,Which of the following options best describe the cover story?,"On the cover: In this issue, Dagenais et al. demonstrate that the characteristic polygonal pattern of grooves on the noses of
dogs, ferrets, and cows develops in the embryo via the mechanical coupling between
epidermal folding and stiff blood vessels. Homogeneous growth of the epidermis makes
it buckle into sharp creases exactly facing an underlying network of blood vessels
because the latter form rigid base points—akin to stiff pillars supporting rising
arches. These results suggest a new concept of “mechanical positional information”
by which material properties of anatomical elements impose local constraints on an
otherwise globally self-organized mechanical process. The resulting skin grooves retain
physiological fluid, thereby keeping the nose wet and, among other effects, facilitating
the collection of chemosensory molecules. Image by Paule Dagenais, Fabrice Berger,
and Michel C. Milinkovitch.",A,MAC_Bench/Cell/Cover/Current Biology/34_3.png,MAC_Bench/Cell/Cover/Current Biology/34_3.png,groundtruth,34_3.txt,MAC_Bench/Cell/Cover/Current Biology/20_17.png,MAC_Bench/Cell/Cover/Current Biology/20_17.png,vith,20_17.txt,MAC_Bench/Cell/Cover/Current Biology/31_11.png,MAC_Bench/Cell/Cover/Current Biology/31_11.png,clip,31_11.txt,MAC_Bench/Cell/Cover/Current Biology/19_4.png,MAC_Bench/Cell/Cover/Current Biology/19_4.png,vitg,19_4.txt,val
Nature Reviews Rheumatology,20_10,Which of the following options best describe the cover story?,"Inspired by the Review on p143.
Cover design: Steven Hall",C,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_10.png,groundtruth,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,train
Nature Reviews Chemistry,8_12,Which of the following options best describe the cover story?,"The use of ratchet mechanisms to directionally bias molecular level dynamics is increasingly well understood but their potential for enabling thermodynamically unfavourable chemical transformations is less well recognised. Mechanisms of light-driven endergonic synthesis parallel the ratchet mechanisms that underpin the operation of artificial molecular motors. Advances in molecular biology, heterogeneous catalysis and artificial photosynthesis also reveal fundamentally related phenomena. The cover image highlights how ratchet mechanisms enable energetically uphill processes by providing an alternative pathway (analogous to Maxwell’s demon) for otherwise-forbidden endergonic chemical reactions (illustrated by the apparently unachievable task given to Sisyphus), powered by an orthogonal exergonic procedure, often through catalysis. Mastery of molecular ratchets could be transformative for expanding the chemist’s toolbox, offering new paradigms in reactivity, complexity and control. See Borsley et al.
Image: Anna Tanczos Cover design: Carl Conway",B,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_1.png,vith,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_12.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_12.png,groundtruth,8_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/2_1.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/2_1.png,vitg,2_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_2.png,clip,1_2.txt,train
Nature Protocols,19_10,Which of the following options best describe the cover story?,"Studying human brain vascular cells with single-cell transcriptomics and organoids
Human brain vascular cells, including endothelial and mural cells, can be purified with FACS and used in many downstream applications, including cell culture, transcriptomics and organoid transplants. This image shows vascular cells labeled with GFP and transplanted on top of induced pluripotent stem cell (iPSC)-derived cortical organoids. See Crouch et al. p603
Image : Elizabeth Crouch, University of California San Francisco. Cover design: S. Whitham",A,MAC_Bench/Nature/Cover/Nature Protocols/19_10.png,MAC_Bench/Nature/Cover/Nature Protocols/19_10.png,groundtruth,19_10.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_1.png,MAC_Bench/Nature/Cover/Nature Protocols/15_1.png,vith,15_1.txt,MAC_Bench/Nature/Cover/Nature Protocols/16_11.png,MAC_Bench/Nature/Cover/Nature Protocols/16_11.png,clip,16_11.txt,MAC_Bench/Nature/Cover/Nature Protocols/13_3.png,MAC_Bench/Nature/Cover/Nature Protocols/13_3.png,vitg,13_3.txt,train
ACS ES&T Water,2025_2,Which of the following options best describe the cover story?,"This Special Issue entitled “3D Printing Technologies for Environmental and Water Applications” highlights the diverse applications of 3D printing technologies in environmental sectors. Owing to their exceptional efficiency, flexible structures, and ease of recovery, 3D-printed catalysts hold significant potential for addressing practical challenges in real-world water environments. The cover artwork was created using OpenAI.com.",C,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png,vith,2024_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_4.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_4.png,vitg,2021_4.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_8.png,clip,2024_8.txt,train
ACS Medicinal Chemistry Letters,2017_9,Which of the following options best describe the cover story?,"X-ray crystal structure of the carboplatin-loaded ferritin nanocage (PDB code 5MIJ). Pt centers coordinate to His49 and His132, on the inner surface of the Ft nanocage. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00025.  View the article.",D,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_4.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_4.png,ave_2,2017_4.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_1.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_1.png,vitg,2025_1.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_9.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_9.png,groundtruth,2017_9.txt,test
Lab Animal,53_3,Which of the following options best describe the cover story?,"New method to extend the survival of SCID pigs
Severe combined immunodeficiency (SCID) pigs do not live long enough to reproduce naturally. Monarch et al. show that reconstituting the immune system of SCID piglets with fetal bone allografts extends their lifespan, allowing them to reach puberty. This new method may improve the availability and use of SCID pigs as a biomedical animal model.
See Monarch et al
Cover image: Illustration by Marina Spence based on photo from Kaylynn Monarch. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Lab Animal/52_4.png,MAC_Bench/Nature/Cover/Lab Animal/52_4.png,clip,52_4.txt,MAC_Bench/Nature/Cover/Lab Animal/50_1.png,MAC_Bench/Nature/Cover/Lab Animal/50_1.png,vith,50_1.txt,MAC_Bench/Nature/Cover/Lab Animal/48_9.png,MAC_Bench/Nature/Cover/Lab Animal/48_9.png,vitg,48_9.txt,MAC_Bench/Nature/Cover/Lab Animal/53_3.png,MAC_Bench/Nature/Cover/Lab Animal/53_3.png,groundtruth,53_3.txt,train
Nature Mental Health,2_2,Which of the following options best describe the cover story?,"Refugee mental health
The number of people displaced by climate-related natural disasters, political conflict and violence continues to grow. Refugees who have often been exposed to horrific conditions at home may also face further trauma in transit. In our November issue, we reflect on refugee mental health, which has often been considered less of a priority than basic needs such as food and shelter or where infrastructure is lacking. The cover symbolizes the potential for the mental health community to better reach and support refugees.
Read more about opportunities for improving refugee mental health in our Editorial, and see Nickerson et al. to learn more about promotive and protective factors for refugee mental health.
Image: Westend61 / Getty Images Plus. Cover design: Marina Spence",A,MAC_Bench/Nature/Cover/Nature Mental Health/2_2.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_2.png,groundtruth,2_2.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Mental Health/1_1.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_1.png,vith,1_1.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,clip,2_3.txt,train
ACS ES&T Air,2024_6,Which of the following options best describe the cover story?,"With positive matrix factorization techniques, sea spray aerosol can be distinguished from secondary marine aerosol. The cover photo, courtesy of Chaosheng Zhang, shows breaking waves over the west coast of Ireland.",B,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,ave_3,2025_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_6.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,ave_2,2024_9.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,clip,2024_3.txt,val
Trends in Cancer,10_5,Which of the following options best describe the cover story?,"Traditional approaches to understand mental health in cancer survivors
often involve the classification of psychopathology into discrete disorders. However,
this approach has faced mounting criticism. In this issue, Haywood et al. propose that
the hierarchical dimensional approach (HiTOP model) diminishes stigma, considers
the individual holistically, and offers a more reliable clinical assessment. The cover
depicts the artist’s mother, a cancer survivor who struggled with mental health post-treatment.
The setting is dark, but in white, an outline of her brain emerges, and from
there, an array of neurons which symbolizes the mind. The image of the neurons
slowly unravels to demonstrate the complexity of the mind as well as the unique
confusion and pain that cancer survivors struggle with. Cover design by Caroline Cha,
VI4 Artist-in-Residence Program.",B,MAC_Bench/Cell/Cover/Trends in Cancer/4_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_6.png,vitg,4_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_5.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_5.png,groundtruth,10_5.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_1.png,ave_0,10_1.txt,MAC_Bench/Cell/Cover/Trends in Cancer/9_12.png,MAC_Bench/Cell/Cover/Trends in Cancer/9_12.png,clip,9_12.txt,test
NATURE MATERIALS,23_8,Which of the following options best describe the cover story?,"Strain-induced electrocaloric
Electrocaloric effects are large in a limited set of materials that display hysteretic first-order phase transitions. Here epitaxial SrTiO3 thin films are strain engineered to achieve anhysteretic second-order phase transitions, with electrocaloric effects enhanced by one order of magnitude over bulk.
See Zhang et al.
Image: BOTUHUI. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_8.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_8.png,groundtruth,23_8.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_8.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_8.png,vith,20_8.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/7_11.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/7_11.png,clip,7_11.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_4.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_4.png,vitg,23_4.txt,train
ACS ES&T Air,2025_1,Which of the following options best describe the cover story?,"An overview of micro air sensor AirGradient OpenAir PM monitor performance evaluation and potentials for PM2.5 source identification in an urban setting (University of Ghana, Accra, Afri-SET reference site) using the reported data.",C,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,ave_1,2025_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_1.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,ave_2,2024_8.txt,val
Nature Neuroscience,27_6,Which of the following options best describe the cover story?,"AAV-based intersectional targeting
Our growing understanding of cell diversity generates an increasing need for molecular tools that selectively target cells on the basis of multiple features. Hughes et al. present an AAV-based toolkit that uses hammerhead ribozymes to achieve intersectional transgene expression. In the cover image, overlapping vinyl records form an abstract representation of Venn diagrams that highlight the intersectionality of complex features.
See Hughes et al.
Image: Kandi Cook, Brandi Rinks, Lindsay Schwarz, and Jenn Sweeney, Memphis, TN. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/Nature Neuroscience/13_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/13_9.png,vitg,13_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_6.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_6.png,groundtruth,27_6.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/18_6.png,MAC_Bench/Nature/Cover/Nature Neuroscience/18_6.png,clip,18_6.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/28_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/28_2.png,vith,28_2.txt,train
Journal of Chemical Theory and Computation,2024_11,Which of the following options best describe the cover story?,"In ionic conductors, a temperature gradient can induce a charge flow. This effect is of paramount importance in energy storage and conversion. We propose a new numerical method for the evaluation of the thermo-electric transport coefficient via Bayesian regression. The image was generated using the",C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2020_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2020_5.png,ave_2,2020_5.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_15.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_15.png,vith,2023_15.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_2.png,clip,2023_2.txt,train
Environmental Science & Technology,2025_3,Which of the following options best describe the cover story?,"This study reveals that allergen-harboring extracellular vesicles (EVs) derived from allergenic species are widespread in the environment. EVs enhance allergen stability and translocation. It suggests a novel vesicle-mediated pathway for allergen dissemination and implications for human health. Background elements of the city, greenery, and houses in the cover art were generated by the image generation function of ChatGPT 4.0.",C,MAC_Bench/ACS/Cover/Environmental Science & Technology/2024_49.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2024_49.png,ave_2,2024_49.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_4.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_4.png,clip,2025_4.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_3.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2015_24.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2015_24.png,ave_1,2015_24.txt,train
Trends in Ecology & Evolution,40_1,Which of the following options best describe the cover story?,"Ethanol is present in many wild fruits, saps, and nectars. Moderate
ethanol intake is associated with nutritional, medicinal, and cognitive benefits,
but many
of these remain understudied for non-human species in natural contexts. On pages
67–79 Anna Bowland and colleagues discuss explanations for ethanol consumption
that span both nutritional and non-nutritional reasons and explore potential medicinal
value or cognitive effects. The cover image shows an adult female chimpanzee Pan
   troglodytes verus selecting and feeding on the ripe fruits of Ficus umbellata at Bossou,
Republic of Guinea. Photo credit: Cyril Ruoso.",B,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_5.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_5.png,vith,34_5.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/40_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/40_1.png,groundtruth,40_1.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/40_2.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/40_2.png,clip,40_2.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/33_6.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/33_6.png,vitg,33_6.txt,test
The Journal of Physical Chemistry C,2025_6,Which of the following options best describe the cover story?,"In this perspective, we discuss how one can correlate computational catalysis results with experimental techniques, such as calorimetry, temperature-programmed desorption, infrared spectroscopy, and XPS measurements. For example, configuration space mapping for the alloying of Ru into Fe(100) through a lattice gas model enables the construction of coverage-dependent microkinetic models involving oxygenated aromatics and identifies a catalytically relevant ground state structure. This structure features Fe (gold spheres) alloyed with Ru at the surface (pink spheres) and Ru at subsurface sites (large red spheres). The lattice gas model accounts for 2-body and 3-body interactions (examples shown), as well as higher-order interactions, which are quantified using first-principles calculations. The lateral interactions between oxygenated aromatics can also be quantified within a mean-field model, allowing for the correlation with core-level binding energy shifts observed in XPS measurements. View the article.",A,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_6.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2019_20.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2019_20.png,vith,2019_20.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2018_21.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2018_21.png,vitg,2018_21.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2019_16.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2019_16.png,clip,2019_16.txt,val
Nature Chemical Engineering,1_10,Which of the following options best describe the cover story?,"Microbial fragrance production
Benzyl acetate, a compound with a jasmine-like scent used in various products, is traditionally made through inefficient plant extraction or chemical methods. Now, Choi, Lee and colleagues have developed a more sustainable method using a metabolically engineered bacterium to produce benzyl acetate, achieving significant production levels in a fermentation process. The cover shows a 300-liter pilot-scale fermentor at KAIST, Korea.
See Choi et al. and Sokolova & Haslinger
Image: Kyeong Rok Choi and Sang Yup Lee, Korea Advanced Institute of Science & Technology. Cover Design: Thomas Phillips.",C,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_11.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_11.png,clip,1_11.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,vitg,1_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_10.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_10.png,groundtruth,1_10.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,ave_3,1_4.txt,val
Trends in Cell Biology,34_4,Which of the following options best describe the cover story?,"Alternative mRNA splicing allows for the expansion and diversification
of the proteome, and this process can be activated by specific stimuli, such as
small molecule metabolites. In this issue, Cui et al. reviewed recent findings on the
metabolic regulation of mRNA splicing, with a focus on the biochemistry of mRNA
splicing and the impact of metabolic cues on alternative mRNA splicing. A creative
approach to combining mRNA splicing and metabolites is shown on the cover, with
sushi representing splicing-regulating metabolites and an orange cat choosing and
emptying plates to represent RNA splicing. Cover design by Qingyu Shi and Colette
Maya Macarios.",C,MAC_Bench/Cell/Cover/Trends in Cell Biology/30_8.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/30_8.png,vith,30_8.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_14.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_14.png,vitg,27_14.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_4.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_4.png,groundtruth,34_4.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/24_5.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/24_5.png,clip,24_5.txt,train
Nature Ecology & Evolution,8_4,Which of the following options best describe the cover story?,"Iron constitution
Photograph of Ganas the Komodo dragon, once housed at London Zoo. Analysis of Ganas’ teeth, along with those of other Komodo dragons in museum collections around the world, has revealed that these lizards have evolved protective iron coatings on the cutting edges and tips of their serrated teeth.
See LeBlanc et al.
Image: Image courtesy of Charlotte Ellis, Zoological Society of London. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_10.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_10.png,ave_3,8_10.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_10.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_10.png,vitg,4_10.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_4.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_4.png,groundtruth,8_4.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_1.png,clip,5_1.txt,train
Macromolecules,2024_19,Which of the following options best describe the cover story?,"UV degradable plastics are synthesized by incorporating phenacyl ester derivatives as either monomers or cross-linkers. These materials undergo complete degradation upon UV exposure, producing acidic byproducts that can be harnessed for other beneficial reactions. The depiction of a plastic bottle decomposing was generated by Dall-E 2.",C,MAC_Bench/ACS/Cover/Macromolecules/2022_18.png,MAC_Bench/ACS/Cover/Macromolecules/2022_18.png,vith,2022_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_11.png,MAC_Bench/ACS/Cover/Macromolecules/2012_11.png,clip,2012_11.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_19.png,MAC_Bench/ACS/Cover/Macromolecules/2024_19.png,groundtruth,2024_19.txt,MAC_Bench/ACS/Cover/Macromolecules/2023_21.png,MAC_Bench/ACS/Cover/Macromolecules/2023_21.png,vitg,2023_21.txt,train
Macromolecules,2024_21,Which of the following options best describe the cover story?,Giant carbosilane dendrimers form a stable and perfect cubic lattice when exposed to solvent vapors. View the article.,B,MAC_Bench/ACS/Cover/Macromolecules/2013_11.png,MAC_Bench/ACS/Cover/Macromolecules/2013_11.png,clip,2013_11.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_21.png,MAC_Bench/ACS/Cover/Macromolecules/2024_21.png,groundtruth,2024_21.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_11.png,MAC_Bench/ACS/Cover/Macromolecules/2012_11.png,vitg,2012_11.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_24.png,MAC_Bench/ACS/Cover/Macromolecules/2022_24.png,vith,2022_24.txt,train
ACS Catalysis,2024_4,Which of the following options best describe the cover story?,"Ru doping in a Ni-MOF rod array regulates the d-band center of Ni-MOF. The Ru dopant activates the adjacent Ni atom in electrochemical NO3RR. As such, the Ni-MOF-Ru rod array delivers enhanced NO3RR activity and Zn-nitrate battery performance.",D,MAC_Bench/ACS/Cover/ACS Catalysis/2019_9.png,MAC_Bench/ACS/Cover/ACS Catalysis/2019_9.png,vitg,2019_9.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_11.png,clip,2024_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_2.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_2.png,vith,2024_2.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_4.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_4.png,groundtruth,2024_4.txt,train
Nano Letters,2025_1,Which of the following options best describe the cover story?,"A kind of chainmail catalyst has been synthesized by the confined flash Joule heating technique, where the isolated platinum atoms are anchored in tungsten carbide nanocrystals and well-encapsulated inside carbon nanotubes, exhibiting excellent catalytic activity and durability toward the acid hydrogen evolution reaction.",B,MAC_Bench/ACS/Cover/Nano Letters/2024_25.png,MAC_Bench/ACS/Cover/Nano Letters/2024_25.png,clip,2024_25.txt,MAC_Bench/ACS/Cover/Nano Letters/2025_1.png,MAC_Bench/ACS/Cover/Nano Letters/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Nano Letters/2018_9.png,MAC_Bench/ACS/Cover/Nano Letters/2018_9.png,vitg,2018_9.txt,MAC_Bench/ACS/Cover/Nano Letters/2024_30.png,MAC_Bench/ACS/Cover/Nano Letters/2024_30.png,ave_1,2024_30.txt,train
Nature Structural & Molecular Biology,31_3,Which of the following options best describe the cover story?,"Protecting pluripotency during embryonic dormancy
A study by Stötzel et al. shows how active DNA demethylation and transcription factor occupancy regulate pluripotency maintenance in dormancy conditions such as diapause.
See Stötzel et al.
Image credit: Kevin Sawford / imageBROKER / Getty images. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_3.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_3.png,groundtruth,31_3.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_9.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_9.png,vitg,31_9.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/29_10.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/29_10.png,clip,29_10.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,ave_1,28_8.txt,train
Trendsin Neurosciences,48_1,Which of the following options best describe the cover story?,"The amygdala is a multi-nuclear limbic system structure that functions
as a primary processing center for social and emotional behaviors in the vertebrate
brain. The term ‘amygdala’ comes from the Greek word for ‘almond’ due to its
characteristic ovoid shape. In this issue of Trends in Neurosciences, Joshua Corbin
and colleagues review how one of the key nuclei of the amygdala, the medial
amygdala, is formed from embryonic development and how these developmental
programs may drive the emergences of innate social behaviors. The cover image
shows an almond tree at two stages of its lifecycle; during springtime when flowers
are blooming and during summer when it has reached its mature state. The arrows
in the young tree invoke the formation of different lineages of amygdala neurons
that form different branches of the tree, which then differentiate into populations
of neurons that control different aspects of medial amygdala regulated behaviors.
Cover image credits: Benjamin Toth/Getty Images; cover design by Joshua Corbin.",B,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_9.png,vith,38_9.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/48_1.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/48_1.png,groundtruth,48_1.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/48_2.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/48_2.png,vitg,48_2.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,clip,47_3.txt,test
ACS Synthetic Biology,2024_11,Which of the following options best describe the cover story?,growing in a solution containing the CNTs.,B,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2016_12.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2016_12.png,ave_2,2016_12.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_11.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_1.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_1.png,clip,2015_1.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_2.png,vitg,2024_2.txt,train
The Journal of Physical Chemistry B,2025_3,Which of the following options best describe the cover story?,"In the chaos of solvation, macromolecules lose their rigidity. An increase in solvent polarity decreases the persistence length of anthranilamide molecular electrets.",D,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_26.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_26.png,clip,2021_26.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_27.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_27.png,vitg,2023_27.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_39.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_39.png,vith,2021_39.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_3.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_3.png,groundtruth,2025_3.txt,train
Industrial & Engineering Chemistry Research,2024_5,Which of the following options best describe the cover story?,"This cover art reveals the intricate reaction network uncovered in batch bis(2-hydroxyethyl) terephthalate (BHET) hydrolysis, showcasing a surprisingly complex reaction pathway. Mastering the chemical intricacies of BHET hydrolysis is essential for optimizing the subsequent polycondensation process, paving the way for more efficient and sustainable polyethylene terephthalate (PET) recycling.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_15.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_15.png,vitg,2023_15.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_5.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_12.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_12.png,vith,2021_12.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_44.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_44.png,clip,2022_44.txt,train
Cell Reports Methods,5_1,Which of the following options best describe the cover story?,"On the cover: The cover image illustrates MMoCHi, a supervised machine learning framework
for cell-type classification of multimodal, single-cell genomics and spatial profiling
data developed by Caron et al. The colored layers and corresponding cell drawings represent different modalities
(e.g., morphology, protein, mRNA), with the bottom row showing the final, classified
form. The images at the bottom are micrographs of lymph nodes, with the colored annotations
from MMoCHi on the right. Credit: Daniel P. Caron.",D,MAC_Bench/Cell/Cover/Cell Reports Methods/2_5.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_5.png,vith,2_5.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_2.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_2.png,vitg,2_2.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_12.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_12.png,clip,3_12.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/5_1.png,MAC_Bench/Cell/Cover/Cell Reports Methods/5_1.png,groundtruth,5_1.txt,val
ACS Applied Bio Materials,2024_5,Which of the following options best describe the cover story?,"In this special issue, guest editors Dr. Md Nurunnabi and Dr. Ryan M. Pearson highlight 15 papers on the latest developments in the field of biomaterials research for immune and gene delivery applications. Front cover art by the team of INMYWORK Studio.",C,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_7.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_7.png,vith,2024_7.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2018_5.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2018_5.png,clip,2018_5.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_5.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_2.png,vitg,2024_2.txt,test
Molecular Plant,17_10,Which of the following options best describe the cover story?,"On the cover: The cover image illustrates a paradox of callus proliferation during in vitro plant regeneration. Hypoxic microenvironments resulted from active callus proliferation
during the in vitro plant regeneration process intrinsically inhibit callus regeneration competence.
Low oxygen levels in callus (shown in red) activate the RAP2.12 protein, which promotes
salicylic acid biosynthesis to inhibit callus cell pluripotency. Given that continuous
cell proliferation is essential for pluripotency maintenance, cell proliferation-induced
hypoxia would be an unavoidable intrinsic limitation for tissue culture. This bottleneck
can be overcome by hyperoxia treatment (i.e., excess supply of oxygen), providing
an opportunity to increase plant tissue culture efficiency. Image by Pil Joon Seo.",D,MAC_Bench/Cell/Cover/Molecular Plant/10_9.png,MAC_Bench/Cell/Cover/Molecular Plant/10_9.png,vitg,10_9.txt,MAC_Bench/Cell/Cover/Molecular Plant/11_12.png,MAC_Bench/Cell/Cover/Molecular Plant/11_12.png,vith,11_12.txt,MAC_Bench/Cell/Cover/Molecular Plant/10_12.png,MAC_Bench/Cell/Cover/Molecular Plant/10_12.png,clip,10_12.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_10.png,MAC_Bench/Cell/Cover/Molecular Plant/17_10.png,groundtruth,17_10.txt,train
JACS Au,2024_1,Which of the following options best describe the cover story?,"Enzymes are thought to possess thermal tolerance and promiscuous activities that are useful for modern biocatalysis. Through ancestral sequence reconstruction (ASR), researchers can revive ancient enzymes to catalyze diverse reactions with a robust scaffold. This perspective summarizes the ASR’s workflow and highlights its implications for enzyme design and exploration of catalytic mechanisms.",B,MAC_Bench/ACS/Cover/JACS Au/2022_7.png,MAC_Bench/ACS/Cover/JACS Au/2022_7.png,vitg,2022_7.txt,MAC_Bench/ACS/Cover/JACS Au/2024_1.png,MAC_Bench/ACS/Cover/JACS Au/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/JACS Au/2023_8.png,MAC_Bench/ACS/Cover/JACS Au/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/JACS Au/2024_10.png,MAC_Bench/ACS/Cover/JACS Au/2024_10.png,vith,2024_10.txt,train
Cell Metabolism,37_1,Which of the following options best describe the cover story?,"On the cover: In this issue, Li et al. develop a high-performance biosensor for arginine, named STAR, which lights up arginine's
functional diversity in physiology and pathology. The cover image is an original artwork
depicting a night sky, resembling the unexplored mystery of arginine metabolism. The
bright stars, arranged in the pattern of the arginine molecular formula, light up
the night sky, which stands for the excellent ability of the STAR sensor in illuminating
arginine metabolism. Artwork by Qing Zhang and Yaqiong Chen.",D,MAC_Bench/Cell/Cover/Cell Metabolism/36_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_3.png,ave_3,36_3.txt,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,clip,37_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/17_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/17_5.png,ave_2,17_5.txt,MAC_Bench/Cell/Cover/Cell Metabolism/37_1.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_1.png,groundtruth,37_1.txt,train
Trends in Plant Science,29_9,Which of the following options best describe the cover story?,"This special issue covers a range of topics on the greatest power plants
have to offer, their specialised metabolism. Plants produce a vast number of structurally
diverse class of metabolites (estimates range from 200 000 to 1 000 000) not for the
benefit of vegetative growth or reproductions but to contribute to vital biological
roles
such as signalling or protection. To date many of these roles as well as the underlying
mechanisms remain unexplored and here we shine the spotlight on new advances, such
as the role of phytosterols. Precise communication between the plant and the diverse
microorganisms (from pathogen to mutualist) is essential to induce the corresponding
adaptive response. Christophe Der and colleagues discuss the complicated interaction
between these partners, and the possible involvement of phytosterols. The cover image
represents a plant cell and two microorganisms (a bad and a good guy) playing the
“happy families sterol card game” to define their interactions. Image credit: Christophe
Der and Jerôme Fromentin, UMR Agroecology.",A,MAC_Bench/Cell/Cover/Trends in Plant Science/29_9.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_9.png,groundtruth,29_9.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/21_2.png,MAC_Bench/Cell/Cover/Trends in Plant Science/21_2.png,ave_2,21_2.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_8.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_8.png,clip,29_8.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/25_11.png,MAC_Bench/Cell/Cover/Trends in Plant Science/25_11.png,vitg,25_11.txt,val
Nature Structural & Molecular Biology,31_5,Which of the following options best describe the cover story?,"Wanderlust kinetics in proteins
In a study by Jiang et al., the authors develop a method to analyze isolated molecules of amino acid transporter GltPh using high-speed atomic force microscopy. The work provides insights into the transporter’s activity mode switching, termed wanderlust kinetics.
See Jiang et al.
Image credit: Moritz Wolf / imageBROKER GmbH & Co. KG / Alamy Stock Photo. Cover design: Allen Beattie",D,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_1.png,vitg,25_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/29_4.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/29_4.png,vith,29_4.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/27_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/27_1.png,clip,27_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_5.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_5.png,groundtruth,31_5.txt,val
ACS Applied Polymer Materials,2024_23,Which of the following options best describe the cover story?,"Nanoindentation and magnetic force microscopy offer a complementary approach to comprehensively characterize the mechanical and magnetic properties of magnetic hydrogels. These techniques play a crucial role in advancing our understanding of the intricate interplay between the structure, mechanical properties, and magnetic behavior, paving the way for tailored applications in various fields, including drug delivery, tissue engineering, and responsive materials design.",D,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_3.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_3.png,vith,2023_3.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_14.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_14.png,vitg,2024_14.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_6.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_6.png,clip,2023_6.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_23.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_23.png,groundtruth,2024_23.txt,train
Nature Reviews Rheumatology,21_2,Which of the following options best describe the cover story?,"Inspired by the Review on p9.
Cover design: Steven Hall",D,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_5.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_5.png,clip,19_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,vith,10_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/17_1.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/17_1.png,vitg,17_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/21_2.png,groundtruth,21_2.txt,train
Journal of Proteome Research,2024_8,Which of the following options best describe the cover story?,https://deepai.org/machine-learning-model/psychedelic-poster-generator,B,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_11.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_11.png,vitg,2016_11.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_8.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2011_11.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2011_11.png,vith,2011_11.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2021_9.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2021_9.png,clip,2021_9.txt,train
ACS Catalysis,2024_23,Which of the following options best describe the cover story?,"Diverse single-atom metal catalysts emerge and stimulate a new pulse in the coal-based PVC industry, which is heavily relying on the prohibited mercury chloride analogues. The synthetic strategies, structure–performance relationships, and reaction mechanisms of these frontiers are reviewed.",A,MAC_Bench/ACS/Cover/ACS Catalysis/2024_23.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_23.png,groundtruth,2024_23.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2018_12.png,MAC_Bench/ACS/Cover/ACS Catalysis/2018_12.png,clip,2018_12.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2022_4.png,MAC_Bench/ACS/Cover/ACS Catalysis/2022_4.png,vith,2022_4.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2022_21.png,MAC_Bench/ACS/Cover/ACS Catalysis/2022_21.png,vitg,2022_21.txt,test
ACS Energy Letters,2024_2,Which of the following options best describe the cover story?,Network analysis reveals the trends of interfacial reactivity of all-solid-state batteries and offers the guiding principles of interface design.,B,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_7.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_7.png,ave_2,2021_7.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_2.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_3.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_3.png,clip,2021_3.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_11.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_11.png,ave_3,2021_11.txt,train
ACS Applied Bio Materials,2024_9,Which of the following options best describe the cover story?,Discarded human eye lens proteins post cataract surgery developed as thin films capable of ion conduction: potential applications as eco-friendly flexible solid polymer electrolytes.,D,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_2.png,vitg,2020_2.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2021_9.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2021_9.png,vith,2021_9.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_9.png,groundtruth,2024_9.txt,train
Trendsin Neurosciences,47_5,Which of the following options best describe the cover story?,"Childhood and adolescence represent periods of particular vulnerability
for air pollution neurotoxicity. In this issue of Trends in Neurosciences, Megan Herting,
Katherine Bottenhorn, and Devyn Cotter discuss the routes whereby air pollution may
reach the brain, and review neurodevelopmental processes impacted by exposure.
They highlight the need for further mechanistic studies, as well as longitudinal analyses
in large and diverse participant samples, including individuals from groups that face
disproportionate exposures and have been historically underrepresented in biomedical
research. Image credits: Chris Madden / Getty Images.",D,MAC_Bench/Cell/Cover/Trendsin Neurosciences/40_4.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/40_4.png,clip,40_4.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/42_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/42_5.png,vith,42_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/40_1.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/40_1.png,vitg,40_1.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_5.png,groundtruth,47_5.txt,train
Nature Reviews Psychology,3_8,Which of the following options best describe the cover story?,"Personality is relatively stable over long timescales but malleable to some degree. In this Review, Jackson and Wright examine the mechanisms responsible for intentional and naturally occurring change as well as mechanisms that promote stability, thereby limiting potential change.
Cover design: David Johnston",D,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,vith,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_3.png,vitg,1_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_2.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_8.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_8.png,groundtruth,3_8.txt,train
Industrial & Engineering Chemistry Research,2024_42,Which of the following options best describe the cover story?,"Lemon juice, a readily available and biodegradable natural substance, was used to prepare carbon dots (CDs) in one step by a microflow approach. The derived CDs",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_43.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_43.png,clip,2021_43.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_42.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_42.png,groundtruth,2024_42.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_38.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_38.png,vith,2020_38.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_27.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_27.png,vitg,2024_27.txt,train
Matter,7_10,Which of the following options best describe the cover story?,"On the cover: To encapsulate the theme of our first annual Special Double Issue, we
invited two covers and split them across the middle (see this issue’s Editorial for the original, unaltered versions). Top: Conceptual design highlighting the critical
role of liquid metal in modulating the wetting behavior of lithium metal on solid-state
electrolyte (see Fu and colleagues). Inspiration was drawn from the technique of blending ink on xuan paper, which is
an essential step in the creation of traditional Chinese painting. The surface of
the solid-state electrolyte resembles the texture of xuan paper, exhibiting an intrinsic
lithiophobic character that impedes effective interface contact and promotes the growth
of dendrites. Bottom: One small step, one giant leap for biohybrid robots. We present
a biohybrid bipedal robot equipped with two legs and cultured skeletal muscle tissues
(see Takeuchi and colleagues). This integration of mechanical components with biological materials enables controlled
walking motions, including forward and stop motion, ultimately evolving towards the
subtle movements characteristic of human bipedal locomotion.",D,MAC_Bench/Cell/Cover/Matter/1_5.png,MAC_Bench/Cell/Cover/Matter/1_5.png,clip,1_5.txt,MAC_Bench/Cell/Cover/Matter/6_10.png,MAC_Bench/Cell/Cover/Matter/6_10.png,vith,6_10.txt,MAC_Bench/Cell/Cover/Matter/1_3.png,MAC_Bench/Cell/Cover/Matter/1_3.png,vitg,1_3.txt,MAC_Bench/Cell/Cover/Matter/7_10.png,MAC_Bench/Cell/Cover/Matter/7_10.png,groundtruth,7_10.txt,train
Nature Physics,20_3,Which of the following options best describe the cover story?,"Electronic motion up close
Charge density waves are wave-like patterns in a material’s electron density that can behave collectively. Shaoxiang Sheng et al. show a direct real-space observation of these collective dynamics at the atomic scale in the transition metal dichalcogenide 2H-NbSe2. Their technique utilizes a terahertz pulse that is enhanced at the tip of a scanning tunnelling microscope to excite oscillations of the charge density wave that vary in magnitude and frequency on the scale of individual atomic impurities. Measuring the current through the tip reveals overlapping phase excitations originating from randomly distributed atomic defects in the surface and creates a spatially structured response of the charge density wave.
See Shaoxiang Sheng et al.
Image: Kurt Lichtenberg, University of Stuttgart. Cover design: Laoise Mac Gabhann",D,MAC_Bench/Nature/Cover/Nature Physics/19_9.png,MAC_Bench/Nature/Cover/Nature Physics/19_9.png,vith,19_9.txt,MAC_Bench/Nature/Cover/Nature Physics/17_6.png,MAC_Bench/Nature/Cover/Nature Physics/17_6.png,ave_3,17_6.txt,MAC_Bench/Nature/Cover/Nature Physics/15_4.png,MAC_Bench/Nature/Cover/Nature Physics/15_4.png,clip,15_4.txt,MAC_Bench/Nature/Cover/Nature Physics/20_3.png,MAC_Bench/Nature/Cover/Nature Physics/20_3.png,groundtruth,20_3.txt,train
Molecular Plant,17_4,Which of the following options best describe the cover story?,"On the cover: The cover image illustrates that Artificial Intelligence (AI) technology such as
the recently developed protein structure prediction tool AlphaFold2 can be used not
only for understanding the complex interactions between plants and microorganisms
but also for designing crop varieties that can adapt to future environments. Plant
pectin methylesterase inhibitors (PMEIs) influence pathogen susceptibility and plant
growth by regulating pectin methyl esterification. However, constitutive expression
of PMEIs can disrupt cell-wall composition, leading to significant tradeoffs between
growth and defense. In this issue, Xia et al. employed AlphaFold tools to redesign
a modified soybean pectin methylesterase inhibitor protein that specifically targets
and inhibits pectin methylesterases (PMEs) of Phytophthora sojae, without affecting the developmental functions of plant PMEs, thereby conferring
enhanced disease resistance in soybean. The Image by Yeqiang Xia with the assistance
of AI: Bing images, chatgpt4/DALL. E and Photoshop software.",A,MAC_Bench/Cell/Cover/Molecular Plant/17_4.png,MAC_Bench/Cell/Cover/Molecular Plant/17_4.png,groundtruth,17_4.txt,MAC_Bench/Cell/Cover/Molecular Plant/16_2.png,MAC_Bench/Cell/Cover/Molecular Plant/16_2.png,vith,16_2.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_6.png,MAC_Bench/Cell/Cover/Molecular Plant/17_6.png,ave_0,17_6.txt,MAC_Bench/Cell/Cover/Molecular Plant/16_1.png,MAC_Bench/Cell/Cover/Molecular Plant/16_1.png,clip,16_1.txt,val
Cell Genomics,4_3,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Jin et al. present a series of articles based on sequencing data from non-invasive
prenatal testing (NIPT) in pregnant women, focusing on multiple phenotypes and diseases.
The cover image represents these articles. On the left is the silhouette of a pregnant
woman; surrounding the fetus in her womb are the radial rings of Manhattan plots,
representing the main content of this series as genome-wide association studies based
on the pregnant woman's genome. The right side of the image contains a blood tube
with a DNA molecule leaping out of it, representing that the samples used in these
studies are from the cell-free DNA in the blood drawn from the pregnant woman's NIPT
examination. Artist credit: Huanhuan Zhu and Linxuan Li, authors from this series
of articles, jointly completed the conceptual design of this cover, with Linxuan Li
completing the graphic illustration.",C,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,vitg,4_12.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,vith,3_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_3.png,MAC_Bench/Cell/Cover/Cell Genomics/4_3.png,groundtruth,4_3.txt,MAC_Bench/Cell/Cover/Cell Genomics/1_3.png,MAC_Bench/Cell/Cover/Cell Genomics/1_3.png,clip,1_3.txt,train
Neuron,113_3,Which of the following options best describe the cover story?,"On the cover: In this issue of Neuron, Wu et al. show an immune-neural circuit at the meningeal-brain interface, where neutrophils
act as sensors of social threats, attenuating threat-related neuronal and behavioral
reactivity by orchestrating T cell-derived interferon signaling. The cover depicts
a lively outer space of the brain. A beige background symbolizes the meninges, while
immune cells are depicted in a variety of colors, such as vibrant yellow polymorphonuclear
neutrophils. These heterogeneous “cells” are interconnected, constituting an immune
network. The homeostatic brain exists beneath this immunologically active environment,
with its originally grayish-white regions being infused with a calming blue, symbolizing
an immune signal that mediates neuronal inhibition and behavioral adaptation. Artwork
Bin Wu and Ling Meng.",B,MAC_Bench/Cell/Cover/Neuron/97_2.png,MAC_Bench/Cell/Cover/Neuron/97_2.png,clip,97_2.txt,MAC_Bench/Cell/Cover/Neuron/113_3.png,MAC_Bench/Cell/Cover/Neuron/113_3.png,groundtruth,113_3.txt,MAC_Bench/Cell/Cover/Neuron/63_1.png,MAC_Bench/Cell/Cover/Neuron/63_1.png,vitg,63_1.txt,MAC_Bench/Cell/Cover/Neuron/67_6.png,MAC_Bench/Cell/Cover/Neuron/67_6.png,vith,67_6.txt,test
Trends in Immunology,45_4,Which of the following options best describe the cover story?,"Our special issue on ‘Neuroimmunology – II’ presents current research
in this discipline, highlighting the crosstalk between the immune and nervous systems
(central or peripheral). The micrograph on the cover shows an optical section through
a
dorsal root ganglion (green) taken from an MHC-II I–Abβ-eGFP reporter mouse at steady
state. The neurons (red) are stained with anti-β3-tubulin antibody (AF568) and the
nuclei
(blue) with DAPI. The image was acquired using a laser-scanning confocal microscope
at 20x magnification, and digitally upscaled using Topaz Gigapixel AI software. Image
credit: Pavel Hanc and Ulrich von Andrian.",A,MAC_Bench/Cell/Cover/Trends in Immunology/45_4.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_4.png,groundtruth,45_4.txt,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,vitg,39_14.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,clip,36_3.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,ave_1,36_4.txt,test
ACS Earth and Space Chemistry,2024_9,Which of the following options best describe the cover story?,"Elemental iron is effective in simultaneous removal of co-existing TcVII and CrVI from contaminated streams when the Fe0/(CrVII + TcVI) molar ratio exceeds 106. Elevated concentrations of Cr(VI) inhibit Fe0 oxidation and removal of contaminants. This cover features work from Drs. Yelena Katsenovich, Florida International University, and Tatiana Levitskaia and Hilary Emerson, Pacific Northwest National Laboratory (PNNL). The original artwork was created by Nathan Johnson, an illustrator at PNNL.",A,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_9.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_12.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_12.png,vith,2023_12.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_6.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_6.png,clip,2024_6.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_1.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_1.png,vitg,2023_1.txt,train
Cancer Cell,42_8,Which of the following options best describe the cover story?,"On the cover: Dyikanov et al. develop a machine learning platform that classifies a patient’s immune system into
five immunotypes using a blood test. On the cover, the railway map represents these
immunotypes as train stations with distinct characteristics. G1-naive and G2-primed,
characteristic of immune systems with the greatest potential to respond to immunogenic
stimuli, are represented by a fertile, green landscape. G3-progressive is a transitional
immunotype represented by a central hub. The G4-chronic station is a heavily developed
urban landscape, symbolizing an immune system shaped by persistent activation and
chronic antigen exposure. G5-suppressive is a desert that represents a depleted immune
system. The trains ferry passengers among different stations along the railway lines,
symbolizing the dynamic nature of one’s immunotype depending on their health or disease
status. (Image credit: Alfiia Mustafina).",A,MAC_Bench/Cell/Cover/Cancer Cell/42_8.png,MAC_Bench/Cell/Cover/Cancer Cell/42_8.png,groundtruth,42_8.txt,MAC_Bench/Cell/Cover/Cancer Cell/39_7.png,MAC_Bench/Cell/Cover/Cancer Cell/39_7.png,vitg,39_7.txt,MAC_Bench/Cell/Cover/Cancer Cell/16_6.png,MAC_Bench/Cell/Cover/Cancer Cell/16_6.png,vith,16_6.txt,MAC_Bench/Cell/Cover/Cancer Cell/28_2.png,MAC_Bench/Cell/Cover/Cancer Cell/28_2.png,clip,28_2.txt,test
ACS Macro Letters,2024_7,Which of the following options best describe the cover story?,"The cover art demonstrates the helix-forming thin films, which have the ability to emit strong circularly polarized luminescence (indicating iCPL behavior) and to absorb specific circularly polarized light (also indicating iCPL behavior).",A,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_7.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2021_1.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2021_1.png,vitg,2021_1.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_3.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_3.png,clip,2020_3.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2022_12.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2022_12.png,vith,2022_12.txt,train
Nature Reviews Earth & Environment,5_11,Which of the following options best describe the cover story?,"Regions with low electricity generation and minor reliance on fossil fuels have potential to avoid fossil fuel dependence and directly transition to renewable energy systems. This Perspective explores the capacity of African countries to transition in such a way while meeting growing electricity demands.
Image credit: Anton Petrus / Getty Images. Cover design: Carl Conway.",C,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_1.png,vith,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_1.png,ave_1,4_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_11.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_11.png,groundtruth,5_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_11.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_11.png,clip,4_11.txt,train
Cell Systems,15_5,Which of the following options best describe the cover story?,"On the cover: Node distance distribution (NDD) ranking of areas in the human brain
surface indicated by colormap. In this issue of Cell Systems, Varga et al. consider time-lags when constructing functional brain networks and employ the statistical
distribution of network properties instead of analyzing a single averaged network.
They unveil a stable functional architecture that is characterized by a strong 0-lag
backbone and weaker, but informative links at different time delays. Image credit:
the authors.",B,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,vitg,7_2.txt,MAC_Bench/Cell/Cover/Cell Systems/15_5.png,MAC_Bench/Cell/Cover/Cell Systems/15_5.png,groundtruth,15_5.txt,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,vith,4_4.txt,MAC_Bench/Cell/Cover/Cell Systems/14_8.png,MAC_Bench/Cell/Cover/Cell Systems/14_8.png,clip,14_8.txt,val
Molecular Therapy,32_7,Which of the following options best describe the cover story?,"On the cover: Bradbury et al. aimed to achieve astrocytic targeting of an adeno-associated virus (AAV) vector for
the treatment of vanishing white matter disease. The image displays a sagittal brain
section from a wild-type mouse after intracerebroventricular delivery of AAV9-GFAP-eGFP.
Neurons (NeuN; red), astrocytes (GFAP; magenta), and the reporter protein (eGFP; green)
are immunofluorescently labeled, demonstrating widespread distribution and astrocytic
targeting through colocalization of eGFP with GFAP (white). Image credit: Sergiy Chornyy,
PhD.",A,MAC_Bench/Cell/Cover/Molecular Therapy/32_7.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_7.png,groundtruth,32_7.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_1.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_1.png,vitg,32_1.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_16.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_16.png,ave_1,32_16.txt,MAC_Bench/Cell/Cover/Molecular Therapy/29_4.png,MAC_Bench/Cell/Cover/Molecular Therapy/29_4.png,clip,29_4.txt,train
NATURE GENETICS,56_7,Which of the following options best describe the cover story?,"Engineering crop polyploid genomes
Generation of clonal gametes in tomato enables polyploid genome design through controlled combination of pre-defined genome haplotypes.
See Wang et al.
Image: Rainer Franzen, Yazhong Wang and Rob Kesseler. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/NATURE GENETICS/49_6.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_6.png,ave_2,49_6.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/55_7.png,MAC_Bench/Nature/Cover/NATURE GENETICS/55_7.png,clip,55_7.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/51_4.png,MAC_Bench/Nature/Cover/NATURE GENETICS/51_4.png,ave_1,51_4.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_7.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_7.png,groundtruth,56_7.txt,val
Science Signaling,2007_388,Which of the following options best describe the cover story?,"COVER This week's Focus Issue, published to complement the Science Special Issue on Single Molecules contains an Editorial Guide as well as three Perspectives that discuss technical advances that allow cell signaling researchers to zoom in on individual molecules. [Image: Christopher Bickel, AAAS]",B,MAC_Bench/Science/Cover/Science Signaling/10_507.png,MAC_Bench/Science/Cover/Science Signaling/10_507.png,clip,10_507.txt,MAC_Bench/Science/Cover/Science Signaling/2007_388.png,MAC_Bench/Science/Cover/Science Signaling/2007_388.png,groundtruth,2007_388.txt,MAC_Bench/Science/Cover/Science Signaling/7_329.png,MAC_Bench/Science/Cover/Science Signaling/7_329.png,vith,7_329.txt,MAC_Bench/Science/Cover/Science Signaling/1_46.png,MAC_Bench/Science/Cover/Science Signaling/1_46.png,vitg,1_46.txt,train
ACS Sustainable Chemistry & Engineering,2025_1,Which of the following options best describe the cover story?,"The cover feature shows a metal-free, phosphorous-doped (P-doped) graphene-based electrocatalyst for the enhanced oxygen evolution reaction (OER). The 3D graphene sheet represents the P-doped graphene surface of the electrode that participates as an electrocatalyst in the OER converting water into dioxygen.",D,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2024_5.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2024_5.png,clip,2024_5.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_47.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_47.png,vitg,2020_47.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2024_1.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2024_1.png,vith,2024_1.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_1.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_1.png,groundtruth,2025_1.txt,train
Accounts of Materials Research,2024_5,Which of the following options best describe the cover story?,"The graphene assembled films demonstrate exceptional electrical, mechanical, and thermal properties. The artwork emphasizes our research on utilizing graphene assembled film-based electronics for RF and microwave technology in the Internet of Everything (IoE), encompassing antenna and antenna array, flexible electronics, RFID, and metasurfaces.",A,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_5.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_3.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_3.png,vith,2022_3.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_10.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_10.png,vitg,2023_10.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_12.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_12.png,clip,2023_12.txt,val
ACS Applied Polymer Materials,2025_1,Which of the following options best describe the cover story?,"A new method for synthesizing urea-based polymers with tetracyanobutadiene chromophores is presented. These polymers show selective  turn-on fluorescence when exposed to fluoride ions in a wide range from 30 μM to 7.2 mM. Fluoride disrupts supramolecular aggregates of the polymer, enhancing emission intensity. The background image was generated using the free NinjaTech AI tool.",B,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,ave_1,2020_12.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_24.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_24.png,clip,2024_24.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_5.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_5.png,ave_2,2022_5.txt,test
NATURE IMMUNOLOGY,25_1,Which of the following options best describe the cover story?,"Sentinel macrophage–nociceptor crosstalk
Why joints are highly responsive to systemic inflammation is unknown. Hasegawa et al. sought to address this question, developing a whole-mount imaging system of the entire synovium to profile the vascular, neuronal and immune components.
See Hasegawa et al.
Image credit: Tetsuo Hasegawa, University of Cambridge. Cover design: Vanitha Selvarajan",A,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_1.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_1.png,groundtruth,25_1.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/15_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/15_5.png,vith,15_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/15_8.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/15_8.png,vitg,15_8.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_3.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_3.png,clip,22_3.txt,train
Science Signaling,2007_405,Which of the following options best describe the cover story?,COVER This week features a  Perspective on variant IFN-α proteins with distinct activities. The image depicts human IFN-α. [Image based on PDB 1rh2.],B,MAC_Bench/Science/Cover/Science Signaling/2007_414.png,MAC_Bench/Science/Cover/Science Signaling/2007_414.png,clip,2007_414.txt,MAC_Bench/Science/Cover/Science Signaling/2007_405.png,MAC_Bench/Science/Cover/Science Signaling/2007_405.png,groundtruth,2007_405.txt,MAC_Bench/Science/Cover/Science Signaling/5_250.png,MAC_Bench/Science/Cover/Science Signaling/5_250.png,vitg,5_250.txt,MAC_Bench/Science/Cover/Science Signaling/1_37.png,MAC_Bench/Science/Cover/Science Signaling/1_37.png,vith,1_37.txt,train
NATURE REVIEWS NEUROSCIENCE,25_3,Which of the following options best describe the cover story?,"‘Synaptic labels’, inspired by the Review on p668.
Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_11.png,vith,22_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_7.png,vitg,22_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,groundtruth,25_3.txt,train
NATURE REVIEWS MICROBIOLOGY,22_2,Which of the following options best describe the cover story?,"Feeding the microbiome, inspired by the Review on p671.
Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_2.png,groundtruth,22_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/12_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/12_2.png,ave_0,12_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/18_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/18_12.png,vith,18_12.txt,train
ACS Energy Letters,2024_3,Which of the following options best describe the cover story?,Lithium tetrafluoroborate as a supplemental salt is systematically investigated in low-ethylene carbonate-content electrolytes. Electrolytes with a trace amount of lithium tetrafluoroborate (0.05 M),B,MAC_Bench/ACS/Cover/ACS Energy Letters/2020_10.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2020_10.png,vitg,2020_10.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_3.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_8.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_8.png,vith,2024_8.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_10.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_10.png,clip,2021_10.txt,train
Cancer Cell,42_10,Which of the following options best describe the cover story?,"On the cover: Du et al. propose a staging model for EBV-related nasopharyngeal carcinoma (NPC) based on a
large multicenter cohort in China, demonstrating its superiority over the currently
used AJCC staging system. The cover image features traditional Chinese embroidery
art. The embroidered Great Wall symbolizes the resolve to conquer NPC, while the nine
beacon towers, arranged from afar to close by, represent the continuous evolution
and improvement of each edition of the staging system, from the first to the ninth
edition of AJCC Stage. The presence of pines and cranes symbolizes the safeguarding
of health. Bathed in sunlight, the emblematic representation encapsulates the journey
toward precision medicine and radiates a message of optimism for the future of NPC
treatment. Image credit: Jun Ma.",A,MAC_Bench/Cell/Cover/Cancer Cell/42_10.png,MAC_Bench/Cell/Cover/Cancer Cell/42_10.png,groundtruth,42_10.txt,MAC_Bench/Cell/Cover/Cancer Cell/29_1.png,MAC_Bench/Cell/Cover/Cancer Cell/29_1.png,vitg,29_1.txt,MAC_Bench/Cell/Cover/Cancer Cell/35_5.png,MAC_Bench/Cell/Cover/Cancer Cell/35_5.png,clip,35_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/22_1.png,MAC_Bench/Cell/Cover/Cancer Cell/22_1.png,ave_2,22_1.txt,test
Chemical & Biomedical ImagingOpen Access,2024_5,Which of the following options best describe the cover story?,"A targeted MRI contrast agent (MT218) that binds to an oncoprotein in the tumor extracellular matrix (extradomain-B fibronectin) enables noninvasive characterization of the aggressiveness, progression, and therapy resistance of prostate cancer with MRI.",D,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_7.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_7.png,vitg,2023_7.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,ave_2,2023_5.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_5.png,groundtruth,2024_5.txt,train
NATURE REVIEWS GENETICS,25_2,Which of the following options best describe the cover story?,"Inspired by the Review on p750.
Cover design: Patrick Morgan",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_2.png,groundtruth,25_2.txt,train
Accounts of Chemical Research,2024_15,Which of the following options best describe the cover story?,"–ligand binding conformations and affinities, is a pivotal element of structure-based virtual screening. We delineate the current status of employing deep learning to enhance molecular docking within the virtual screening paradigm, highlighting our contributions (KarmaDock and RTMScore) in this realm. Furthermore, we pinpoint the extant challenges and envision future prospects, drawing profound insights from our scholarly endeavors.",D,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_22.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_22.png,vith,2021_22.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_4.png,clip,2020_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_4.png,vitg,2019_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_15.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_15.png,groundtruth,2024_15.txt,val
Nature Human Behaviour,8_6,Which of the following options best describe the cover story?,"Making sense of goal persistence
To attain goals, we frequently need to persevere. However, people sometimes show too much commitment to a goal, despite better alternatives — especially if they have invested a lot of time or money. Holton et al. use fMRI, lesion data and computational modelling to show that over-persistence with a chosen goal is driven by selective attention (mediated by the ventromedial prefrontal cortex ), which prioritizes information related to the current goal and reduces sensitivity to attractive alternatives.
See Holton et al.
Image: Magdalena Adomeit. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_3.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_3.png,vitg,8_3.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_9.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_9.png,clip,5_9.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,ave_2,4_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_6.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_6.png,groundtruth,8_6.txt,train
ACS Applied Polymer Materials,2024_2,Which of the following options best describe the cover story?,"The ACS AMI Family “2024 Early Career Forum” highlights groundbreaking research and innovative ideas from the emerging authors in the scientific community on a broad range of topics. This edition of the Forum showcases 135 exceptional contributions from early-career scientists worldwide, published across ACS Applied Materials & Interfaces, ACS Applied Bio Materials, ACS Applied Electronic Materials, ACS Applied Engineering Materials, ACS Applied Energy Materials, ACS Applied Nano Materials, ACS Applied Optical Materials, and ACS Applied Polymer Materials.",D,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_11.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_11.png,ave_2,2023_11.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_6.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_6.png,vitg,2023_6.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_21.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_21.png,clip,2024_21.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_2.png,groundtruth,2024_2.txt,train
Trends in Cell Biology,35_1,Which of the following options best describe the cover story?,"Organelle communication is a growing research field, and its
impairment is increasingly associated with mechanisms of cellular dysfunction. Recent
studies have shed light on the pivotal role of lipids in inter-organelle communication,
revealing their influence on processes such as organelle membrane fission and
remodeling. In this issue, Domingues et al. explore how lipids mediate inter-organelle
communication. The authors highlight emerging techniques that improve lipid
detection and quantification, paving the way for a systematic understanding of lipid-mediated
intracellular communication. Cover design by Neuza Domingues.",D,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_9.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_9.png,vith,26_9.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_3.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_3.png,vitg,27_3.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_10.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_10.png,clip,34_10.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/35_1.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/35_1.png,groundtruth,35_1.txt,train
Trends in Endocrinology & Metabolism,35_10,Which of the following options best describe the cover story?,"A tug-of-war between bacteria and immune cells for certain metabolites
gives the winning side the chance to survive. In recent years, it has become apparent
that metabolism is crucial for immune cell function; it is now also clear that pathogens
have adapted to utilise cellular metabolism for their own survival. This month, Almeida
et al. (pp. 235—248) detail how macrophage metabolism can accumulate intermediate
metabolites to interfere with bacterial metabolism. In retaliation, certain bacteria
have
adapted macrophage metabolism to confer fitness advantages. The cover represents
this constant battle between macrophages (in blue) and bacteria (in purple) over
metabolites for survival. Cover credit: concept design from Ayesha Dhillon-LaBrooy
and Luís Almeida; illustration/colourisation from Ying Pung.",D,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_9.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_9.png,clip,33_9.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_4.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_4.png,vitg,26_4.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,vith,27_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_10.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_10.png,groundtruth,35_10.txt,train
Structure,32_2,Which of the following options best describe the cover story?,"On the cover: The β-carotene-binding protein (BBP) is a water-soluble pigment-protein
complex responsible for the bright yellow coloration in the integuments of gregarious
phase nymphs and adult males of the desert locust Schistocerca gregaria. The image symbolically depicts a swarm of desert locusts with one yellow individual
illuminated by sunlight, thus creating an illusion of the BBP crystal structure. The
structure determined by Egorkin et al. reveals the β-carotene embedment mechanism utilized by BBP and shows a strong structural
complementarity between ligand and protein. Image credit: Lavrova Anastasia.",C,MAC_Bench/Cell/Cover/Structure/22_7.png,MAC_Bench/Cell/Cover/Structure/22_7.png,vith,22_7.txt,MAC_Bench/Cell/Cover/Structure/24_6.png,MAC_Bench/Cell/Cover/Structure/24_6.png,vitg,24_6.txt,MAC_Bench/Cell/Cover/Structure/32_2.png,MAC_Bench/Cell/Cover/Structure/32_2.png,groundtruth,32_2.txt,MAC_Bench/Cell/Cover/Structure/29_6.png,MAC_Bench/Cell/Cover/Structure/29_6.png,clip,29_6.txt,val
NATURE BIOTECHNOLOGY,43_1,Which of the following options best describe the cover story?,"Citizen science improves microbial phylogeny
To crowdsource the alignment of 1 million RNA sequences from the human microbiome, Sarrazin-Gendron et al. created a minigame integrated within a popular commercial video game. More than 4 million participants contributed to improving a multiple sequence alignment for microbial phylogeny estimations and association.
See Sarrazin-Gendron et al.
Image: The Gearbox Entertainment Company. Cover design: Erin Dewalt",C,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/36_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/36_4.png,clip,36_4.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/37_11.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/37_11.png,ave_3,37_11.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/43_1.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/43_1.png,groundtruth,43_1.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/30_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/30_4.png,vitg,30_4.txt,train
BDJ,237_5,Which of the following options best describe the cover story?,"In this issue
This issue features articles on MRONJ, virtual clinics, and polishing systems.

Cover image: From 2019. The BDA Museum series which inspired the cover on this current issue was a direct lookback and comparison with modern practice and was published in the second half of 2019. One item was an operating face mask from the 1920s, complete with its stylish box (from Vol 227 Issue 8, 25 October 2019). As the series drew to a close at the end of that year, no one had any notion whatsoever of the pandemic that was about to engulf us in 2020 when the use of personal protective equipment became such a crucial element of enabling continuing health care.
©Tim Marrs",D,MAC_Bench/Nature/Cover/BDJ/230_4.png,MAC_Bench/Nature/Cover/BDJ/230_4.png,ave_1,230_4.txt,MAC_Bench/Nature/Cover/BDJ/227_5.png,MAC_Bench/Nature/Cover/BDJ/227_5.png,clip,227_5.txt,MAC_Bench/Nature/Cover/BDJ/229_7.png,MAC_Bench/Nature/Cover/BDJ/229_7.png,ave_2,229_7.txt,MAC_Bench/Nature/Cover/BDJ/237_5.png,MAC_Bench/Nature/Cover/BDJ/237_5.png,groundtruth,237_5.txt,val
Chemical Research in Toxicology,2024_7,Which of the following options best describe the cover story?,"Nitrosamines are potent human carcinogens that require metabolic activation to a diazonium reactive intermediate, which subsequently reacts with DNA. However, not all nitrosamines are equally potent and/or carcinogenic, and quantum mechanical assessment of the pathways involved with activation can help elucidate and predict reactivity and nitrosamine potency.",C,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_7.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_7.png,vitg,2017_7.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_8.png,clip,2012_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_7.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2020_5.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2020_5.png,vith,2020_5.txt,train
Nature Reviews Rheumatology,20_8,Which of the following options best describe the cover story?,"Inspired by the Review on p258
Cover design: Steven Hall",C,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_9.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_9.png,ave_1,10_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_8.png,groundtruth,20_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_9.png,vith,20_9.txt,train
Trends in Chemistry,6_9,Which of the following options best describe the cover story?,"The ability to image the dynamic processes, bonding forces and
conformational changes of biomacromolecules in a liquid environment in real time
would be vital to provide a deeper understanding of fundamental biological principles.
As an emerging method to reach this goal, liquid-phase electron microscopy (LP-EM)
can provide unique insights into complex structures such as proteins, lipids, and
nucleic
acids. In their Forum article, Huan Wang and colleagues highlight the progress made
in single-molecule LP-EM research so far, including use of deep learning methods,
and discuss future prospects for this technique to address unanswered questions in
biochemistry and biophysics. Image credit: GettyImages/Westend61",A,MAC_Bench/Cell/Cover/Trends in Chemistry/6_9.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_9.png,groundtruth,6_9.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/3_13.png,MAC_Bench/Cell/Cover/Trends in Chemistry/3_13.png,clip,3_13.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/3_3.png,MAC_Bench/Cell/Cover/Trends in Chemistry/3_3.png,ave_1,3_3.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/4_3.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_3.png,vitg,4_3.txt,train
Molecular Therapy,32_3,Which of the following options best describe the cover story?,"On the cover:Pitner et al. demonstrated that non-differentiating B cells act as “decoys” that blunt the generation
of factor VIII inhibitors in a murine model of hemophilia A. The image displays a
coronal spleen section from a CD45.1 mouse after intravenous delivery of Blimp1-knockout
decoy MD4 B cells and intraperitoneal immunization with HEL-OVA. Decoy B cells (CD45.2,
magenta) dominate the light zones of germinal centers (GL7, green) within B cell follicles
(IgD, blue). CD4 T cells (CD4, red) and marginal zone macrophages (CD169, gray) are
also pictured. Image credit: Jaime L. Chao.",A,MAC_Bench/Cell/Cover/Molecular Therapy/32_3.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_3.png,groundtruth,32_3.txt,MAC_Bench/Cell/Cover/Molecular Therapy/25_2.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_2.png,clip,25_2.txt,MAC_Bench/Cell/Cover/Molecular Therapy/28_11.png,MAC_Bench/Cell/Cover/Molecular Therapy/28_11.png,vith,28_11.txt,MAC_Bench/Cell/Cover/Molecular Therapy/30_16.png,MAC_Bench/Cell/Cover/Molecular Therapy/30_16.png,vitg,30_16.txt,train
Nature Water,2_6,Which of the following options best describe the cover story?,"Solid water
Water in solid form, including glaciers, snow, ice caps and permafrost, plays a crucial role in both the water and climate systems. The cover shows a stream flowing through the ice landscape on top of the Greenland ice sheet not far from the town of Kangerlussuaq, southwest Greenland. Each summer, a huge number of surface streams form on the Greenland ice sheet, transporting meltwater that influences the ice sheet's movement and eventually reaches the ocean, where it contributes to global sea level rise.
Credit: Image courtesy of Åsa Rennermalm. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Water/2_7.png,MAC_Bench/Nature/Cover/Nature Water/2_7.png,ave_2,2_7.txt,MAC_Bench/Nature/Cover/Nature Water/2_6.png,MAC_Bench/Nature/Cover/Nature Water/2_6.png,groundtruth,2_6.txt,MAC_Bench/Nature/Cover/Nature Water/1_7.png,MAC_Bench/Nature/Cover/Nature Water/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Water/1_2.png,MAC_Bench/Nature/Cover/Nature Water/1_2.png,vitg,1_2.txt,test
The Journal of Physical Chemistry Letters,2025_3,Which of the following options best describe the cover story?,"Designing self-illuminating photocatalysts for next-generation lithium-oxygen batteries: Enhancing photo-assisted energy storage with persistent overpotential reduction, stable performance under intermittent illumination, and promising applications in space exploration and energy systems for low-light environments.",C,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2024_31.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2024_31.png,vith,2024_31.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2024_47.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2024_47.png,ave_1,2024_47.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_3.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_50.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_50.png,clip,2021_50.txt,train
Nature Catalysis,7_3,Which of the following options best describe the cover story?,"Engineering nitrogen fixation
The generation of metallocentre-containing nitrogenase for N2 fixation in a non-diazotrophic host has proven to be an intricate task. Now, Markus W. Ribbe, Yilin Hu and colleagues successfully expressed and isolated active Mo-nitrogenase with complete metallocentres in Escherichia coli by integrating genes from Azotobacter vinelandii and Methanosarcina acetivorans. The engineered E. coli strain can fix nitrogen during growth and produces ammonia.
See Solomon et al.
Image: Alex Whitworth. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/Nature Catalysis/7_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_3.png,groundtruth,7_3.txt,MAC_Bench/Nature/Cover/Nature Catalysis/5_9.png,MAC_Bench/Nature/Cover/Nature Catalysis/5_9.png,clip,5_9.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_7.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_7.png,vitg,2_7.txt,MAC_Bench/Nature/Cover/Nature Catalysis/4_8.png,MAC_Bench/Nature/Cover/Nature Catalysis/4_8.png,vith,4_8.txt,train
Precision Chemistry,2024_4,Which of the following options best describe the cover story?,"Constructing charge-transfer channels in ZnIn2S4 by doping Ru single atoms (SAs), where the photogenerated electrons migrate from Ru SAs to S sites, as a result of enhanced separation of electron-hole pairs, leading to the ultrahigh H2 productivity under visible light irradiation in the absence of sacrificial agents.",C,MAC_Bench/ACS/Cover/Precision Chemistry/2023_6.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_6.png,ave_2,2023_6.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_12.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_12.png,ave_3,2024_12.txt,train
Industrial & Engineering Chemistry Research,2024_24,Which of the following options best describe the cover story?,This picture represents a hybridized membrane featuring lotus leaf mimetic hierarchies composed of wrinkled reduced graphene oxide microspheres and polytetrafluoroethylene nanorods for high-efficiency desalination via vacuum membrane distillation.,D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,clip,2021_45.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_34.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_34.png,ave_2,2020_34.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_6.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_6.png,vitg,2023_6.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_24.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_24.png,groundtruth,2024_24.txt,val
NATURE METHODS,21_5,Which of the following options best describe the cover story?,"Focus on advanced AI in biology
Advanced artificial intelligence (AI)-based methods are having a transformative impact on biological research, as explored in this special issue.
See Editorial
Image: Weiquan Lin / Getty Images. Cover design: Thomas Phillips",A,MAC_Bench/Nature/Cover/NATURE METHODS/21_5.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_5.png,groundtruth,21_5.txt,MAC_Bench/Nature/Cover/NATURE METHODS/20_6.png,MAC_Bench/Nature/Cover/NATURE METHODS/20_6.png,ave_3,20_6.txt,MAC_Bench/Nature/Cover/NATURE METHODS/15_9.png,MAC_Bench/Nature/Cover/NATURE METHODS/15_9.png,vitg,15_9.txt,MAC_Bench/Nature/Cover/NATURE METHODS/19_7.png,MAC_Bench/Nature/Cover/NATURE METHODS/19_7.png,clip,19_7.txt,test
NATURE REVIEWS IMMUNOLOGY,24_8,Which of the following options best describe the cover story?,"Regulatory T cells in the Brain, inspired by the Review on p326.
Cover design: Simon Bradbrook",A,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_8.png,groundtruth,24_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_12.png,vitg,14_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/22_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/22_6.png,vith,22_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/15_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/15_9.png,clip,15_9.txt,train
Matter,7_5,Which of the following options best describe the cover story?,"On the cover: This month is our fourth annual researcher's choice issue—an issue that
contains zero original research articles! Our intent is to highlight articles across
materials science that authors find interesting—i.e., researcher's choice—via preview
articles only. This month's cover reflects this variety across materials science,
with a humorous take on an academic setting and lively discussions among peers. Like
the cover illustration, we hope you will find a preview or two enjoyable in this year's
collection!",C,MAC_Bench/Cell/Cover/Matter/6_2.png,MAC_Bench/Cell/Cover/Matter/6_2.png,ave_1,6_2.txt,MAC_Bench/Cell/Cover/Matter/4_5.png,MAC_Bench/Cell/Cover/Matter/4_5.png,clip,4_5.txt,MAC_Bench/Cell/Cover/Matter/7_5.png,MAC_Bench/Cell/Cover/Matter/7_5.png,groundtruth,7_5.txt,MAC_Bench/Cell/Cover/Matter/5_5.png,MAC_Bench/Cell/Cover/Matter/5_5.png,vith,5_5.txt,train
NATURE ENERGY,10_1,Which of the following options best describe the cover story?,"Electrifying carbon capture
One approach to carbon capture is to react CO2 with an alkaline absorbent. To release the CO2 and regenerate the absorbent, substantial amounts of heat and multiple steps may be needed. Zhang et al. report one-step electrochemical regeneration of CO2 and absorbent at ambient conditions using a porous solid electrolyte reactor.
See Zhang et al.
Image: Xiao Zhang, Haotian Wang, Rice University. Cover design: Thomas Phillips",B,MAC_Bench/Nature/Cover/NATURE ENERGY/2_9.png,MAC_Bench/Nature/Cover/NATURE ENERGY/2_9.png,clip,2_9.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/10_1.png,MAC_Bench/Nature/Cover/NATURE ENERGY/10_1.png,groundtruth,10_1.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/5_6.png,MAC_Bench/Nature/Cover/NATURE ENERGY/5_6.png,vitg,5_6.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/2_4.png,MAC_Bench/Nature/Cover/NATURE ENERGY/2_4.png,vith,2_4.txt,train
Trends in Plant Science,29_12,Which of the following options best describe the cover story?,"The Nobel Prize in Chemistry for 2022 was awarded to the pioneers of
Lego-like ‘click chemistry’ – combinatorial chemistry with remarkable modularity and
diversity. It has been applied to a wide variety of biological systems, from microorganisms
to plants and animals, including humans. Ming-Ming Chen, Peng Wang and colleagues
review click chemistry reactions and their applications in plant systems to visualize
plant
biological processes. Click chemistry is one of an array of modern tools highlighted
in
this special issue that offer new opportunities to explore and understand the underlying
molecular mechanisms of many biological processes in plants, as well as finding
applications in agriculture for delivering smart crops fit for the 21st century. Image
credit:
Ming-Ming Chen.",B,MAC_Bench/Cell/Cover/Trends in Plant Science/17_6.png,MAC_Bench/Cell/Cover/Trends in Plant Science/17_6.png,clip,17_6.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_12.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_12.png,groundtruth,29_12.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_13.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_13.png,vith,29_13.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/15_12.png,MAC_Bench/Cell/Cover/Trends in Plant Science/15_12.png,vitg,15_12.txt,train
Journal of the American Chemical Society,2024_14,Which of the following options best describe the cover story?,"The Pd/Cu bimetallic catalytic system demonstrates precise synergistic interaction, akin to interlocking gears, enabling enantio- and diastereodivergent Wacker-type dicarbofunctionalization of alkene-tethered aryl triflates with imino esters. A series of 2-indanyl motifs bearing adjacent carbon stereocenters could be easily synthesized.",C,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_3.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_3.png,clip,2010_3.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_17.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_17.png,vith,2009_17.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_14.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_6.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_6.png,vitg,2010_6.txt,val
Accounts of Chemical Research,2024_4,Which of the following options best describe the cover story?,"Late-stage halogenation has gained prominence for its role in diversifying and functionalizing complex molecules, including natural products and pharmaceutical intermediates. Recent strategies, characterized by mild conditions, accessible and stable catalysts, and broad functional group tolerance, provide streamlined approaches for the synthesis of halogenated drugs, natural products, and peptides.",A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_7.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_7.png,clip,2012_7.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_9.png,ave_1,2022_9.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_6.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_6.png,vitg,2022_6.txt,train
Nature Physics,20_7,Which of the following options best describe the cover story?,"Neutrinos probe quantum gravity
The existence of fluctuations in the metric of spacetime induced by quantum gravity would have an impact on neutrinos produced in cosmic-ray air showers. They would lose their quantum coherence, causing their flavour oscillations to change. The IceCube collaboration reports a search for this effect but finds no evidence for it, thus constraining the magnitude of anomalous decoherence from quantum gravity.
See IceCube Collaboration
Image: Alexa Nelson / IceCube. Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/Nature Physics/18_5.png,MAC_Bench/Nature/Cover/Nature Physics/18_5.png,ave_1,18_5.txt,MAC_Bench/Nature/Cover/Nature Physics/17_2.png,MAC_Bench/Nature/Cover/Nature Physics/17_2.png,vitg,17_2.txt,MAC_Bench/Nature/Cover/Nature Physics/20_7.png,MAC_Bench/Nature/Cover/Nature Physics/20_7.png,groundtruth,20_7.txt,MAC_Bench/Nature/Cover/Nature Physics/16_10.png,MAC_Bench/Nature/Cover/Nature Physics/16_10.png,clip,16_10.txt,train
Trendsin Neurosciences,47_10,Which of the following options best describe the cover story?,"Microglia are the primary immune cells of the central nervous system
(CNS). Emerging evidence highlights the roles of homeostatic microglia in regulating
neuronal activity, interacting with synapses, tuning neural circuits, and modulating
behavior. In this issue of Trends in Neurosciences, Shunyi Zhao, Anthony Umpierre,
and Long-Jun Wu review how microglia sense and regulate neuronal activity through
synaptic interactions, thereby directly engaging with neural networks and influencing
behavior in adult mice. The cover features a 3D reconstructed two-photon image of
microglia (blue) interacting with cortical excitatory neurons and apical dendrites
(red).
The cover image was acquired and processed by Shunyi Zhao.",C,MAC_Bench/Cell/Cover/Trendsin Neurosciences/36_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/36_9.png,clip,36_9.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/44_6.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/44_6.png,ave_1,44_6.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_10.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_10.png,groundtruth,47_10.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/36_7.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/36_7.png,vith,36_7.txt,train
Nature Human Behaviour,8_4,Which of the following options best describe the cover story?,"Mindfulness for stress
Do self-administered mindfulness interventions actually work for reducing stress? Sparacio et al. examined the efficacy of four different mindfulness exercises (body scan, mindful breathing, mindful walking and loving kindness). They found that all four interventions reduced participants’ self-reported stress compared to listening to a story excerpt. Body scan was the exercise with the largest stress reduction effect.
See Sparacio et al.
Image: Stellalevi/DigitalVision Vectors/Getty. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Human Behaviour/3_12.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/3_12.png,vitg,3_12.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_4.png,groundtruth,8_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_3.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_3.png,clip,7_3.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,vith,8_2.txt,val
Trends in Plant Science,29_11,Which of the following options best describe the cover story?,"Precise communication between the pollen tube and the synergid
cells within the ovule is essential to coordinate pollen tube rupture, followed by
delivery and reception of the sperm cells. Alice Baillie and colleagues provide insight
into the complicated interaction between the receptor-like kinases involved, and their
co-receptors and ligands. The cover image represents the detail of an arabidopsis
flower,
with male pollen tubes travelling down the transmitting tract towards the ovule micropyles
where the tubes interact with the female synergid cells. Image credit: Jen Sloan.",C,MAC_Bench/Cell/Cover/Trends in Plant Science/23_7.png,MAC_Bench/Cell/Cover/Trends in Plant Science/23_7.png,vitg,23_7.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/30_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/30_1.png,vith,30_1.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_11.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_11.png,groundtruth,29_11.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/21_13.png,MAC_Bench/Cell/Cover/Trends in Plant Science/21_13.png,clip,21_13.txt,train
Nature Photonics,18_11,Which of the following options best describe the cover story?,"Ultrafast dual-comb spectroscopy
An artistic image of a dual-frequency comb that is generated by using an optical parametric oscillator to convert a pair of near-infrared combs into the mid-infrared. The generated combs enable nanosecond-timescale spectroscopy for probing the ultrafast dynamics found in supersonic gas jets, explosions and chemical kinetics.
See Long et al.
Image: Brad Baxley, Part to Whole, LLC. Cover Design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,vitg,16_12.txt,MAC_Bench/Nature/Cover/Nature Photonics/1_5.png,MAC_Bench/Nature/Cover/Nature Photonics/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Photonics/8_7.png,MAC_Bench/Nature/Cover/Nature Photonics/8_7.png,vith,8_7.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_11.png,MAC_Bench/Nature/Cover/Nature Photonics/18_11.png,groundtruth,18_11.txt,train
Crystal Growth & Design,2025_4,Which of the following options best describe the cover story?,"With the exploration of tyramine's role as a prolific coformer, this study delves into its extensive co-crystallization capabilities with diverse acids, analyzing crystal structures and electron density to uncover the key factors driving its versatility in multicomponent crystal formation.",C,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_4.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_4.png,ave_1,2024_4.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_4.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,vitg,2018_1.txt,test
ACS Food Science & Technology,2024_4,Which of the following options best describe the cover story?,"The functional exploitation of wild medicinal plants by local stakeholders requires an in-depth quali–quantitative knowledge of their specialized metabolites. This is mandatory for pursuing sustainable and innovative value chains. In this context, field marigold from five neighboring Cilento coast locations represents our study case.",A,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_4.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_7.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_7.png,ave_2,2023_7.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_5.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_5.png,clip,2022_5.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,vitg,2024_10.txt,train
Science Signaling,2007_395,Which of the following options best describe the cover story?,"COVER This week features a Perspective on erythropoietin (Epo) signaling and the possibility that Epo may promote the growth of cancer cells. The image depicts two possible forms of the Epo receptor (a homodimer and a heterodimer) that may mediate Epo signaling in cancer cells. [Image: Preston Huey, AAAS]",D,MAC_Bench/Science/Cover/Science Signaling/1_46.png,MAC_Bench/Science/Cover/Science Signaling/1_46.png,vitg,1_46.txt,MAC_Bench/Science/Cover/Science Signaling/5_245.png,MAC_Bench/Science/Cover/Science Signaling/5_245.png,vith,5_245.txt,MAC_Bench/Science/Cover/Science Signaling/5_250.png,MAC_Bench/Science/Cover/Science Signaling/5_250.png,clip,5_250.txt,MAC_Bench/Science/Cover/Science Signaling/2007_395.png,MAC_Bench/Science/Cover/Science Signaling/2007_395.png,groundtruth,2007_395.txt,train
Cell Reports Physical Science,5_8,Which of the following options best describe the cover story?,"On the cover: Li et al. explore a soft and watery artificial muscle inspired by jellyfish, enhancing the
design of versatile and untethered underwater robots. The image features three applications:
a jellyfish-type robot at the center, a flapping robot at the bottom left, and a soft
robotic gripper at the top left. These examples underscore the muscle's potential
to enable complex and biomimetic movements in underwater robotics. The cover was made
by Xinge Li, Dingnan Rao, and Xuxu Yang.",C,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_6.png,vith,3_6.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_6.png,ave_2,1_6.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_8.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_8.png,groundtruth,5_8.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_6.png,clip,2_6.txt,train
ACS Central Science,2024_3,Which of the following options best describe the cover story?,"The signature of spin liquid is its diffraction pattern containing structured diffuse scattering. The diffraction patterns of the seven highest symmetry frustrated magnetic topologies are shown here, tiled into a pattern evoking traditional weaving.",A,MAC_Bench/ACS/Cover/ACS Central Science/2024_3.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_12.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_12.png,vith,2023_12.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_9.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_9.png,vitg,2024_9.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_7.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_7.png,clip,2023_7.txt,train
Nature Chemical Engineering,1_8,Which of the following options best describe the cover story?,"Digitizing CO2 electrolyzers
The design of electrochemical reactors that convert CO2 into valuable chemicals and fuels is made challenging by the lack of computational models that capture the complex physics and chemistry of these systems. Now, Adam Weber and colleagues have developed a comprehensive continuum model that links ion, water and gas transport with coupled ion–electron transfer kinetics to quantify rate-limiting phenomena and trade-offs in reactor design. The cover shows how this digital model complements CO2 reduction experiments to accelerate the development of improved reactors.
See Lees et al. and Elgazzar & Wang
Image: Justin Bui, Francisco Galang and Samantha Trieu, Lawrence Berkeley National Laboratory. Cover design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_8.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_8.png,groundtruth,1_8.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_2.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_2.png,ave_3,1_2.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,ave_2,1_5.txt,train
Nature Reviews Clinical Oncology,21_3,Which of the following options best describe the cover story?,"Understanding tumour mutational burden, inspired by the Review on p725.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_12.png,vitg,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,vith,19_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_6.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_6.png,clip,19_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_3.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_3.png,groundtruth,21_3.txt,train
Science Signaling,2007_379,Which of the following options best describe the cover story?,"COVER This week features a Perspective on nonconventional functions of the phagocytic NADPH oxidase (NOX2). The image depicts a neutrophil extracellular trap (NET), formation of which depends on reactive oxygen species generated through NOX2 activity. [Image: Volker Brinkmann, Max-Planck Institute for Infection Biology, 10117 Berlin, Germany]",B,MAC_Bench/Science/Cover/Science Signaling/5_246.png,MAC_Bench/Science/Cover/Science Signaling/5_246.png,clip,5_246.txt,MAC_Bench/Science/Cover/Science Signaling/2007_379.png,MAC_Bench/Science/Cover/Science Signaling/2007_379.png,groundtruth,2007_379.txt,MAC_Bench/Science/Cover/Science Signaling/5_233.png,MAC_Bench/Science/Cover/Science Signaling/5_233.png,vith,5_233.txt,MAC_Bench/Science/Cover/Science Signaling/8_366.png,MAC_Bench/Science/Cover/Science Signaling/8_366.png,vitg,8_366.txt,train
Structure,32_10,Which of the following options best describe the cover story?,"On the cover: Pestiviruses bear substantial economic importance within the domain
of viruses affecting livestock. Among them, atypical porcine pestivirus (APPV) and
Norway rat pestivirus (NRPV) exhibit relatively low sequence conservation in their
surface glycoprotein E2. Aitkenhead et al.'s work delves into describing the structures of these proteins. These glycoproteins
serve as the primary target for neutralizing antibodies, and they play crucial roles
in cell attachment and the process of viral fusion. Image courtesy of Kamel El Omari.",B,MAC_Bench/Cell/Cover/Structure/27_11.png,MAC_Bench/Cell/Cover/Structure/27_11.png,vitg,27_11.txt,MAC_Bench/Cell/Cover/Structure/32_10.png,MAC_Bench/Cell/Cover/Structure/32_10.png,groundtruth,32_10.txt,MAC_Bench/Cell/Cover/Structure/22_7.png,MAC_Bench/Cell/Cover/Structure/22_7.png,vith,22_7.txt,MAC_Bench/Cell/Cover/Structure/25_3.png,MAC_Bench/Cell/Cover/Structure/25_3.png,clip,25_3.txt,val
Nature Reviews Neurology,20_4,Which of the following options best describe the cover story?,"Immune-related adverse effects of checkpoint inhibition, inspired by the Review on p509.
Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_9.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_9.png,vith,19_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_4.png,groundtruth,20_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_3.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_3.png,clip,20_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_1.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_1.png,vitg,19_1.txt,test
Nature Food,5_9,Which of the following options best describe the cover story?,"Smart food labelling
Food labels carry information about a product’s identity, ingredients, and allergenic and nutritional properties, as well as how it should be handled, stored and consumed safely. Front-of-package labels are therefore important for consumer protection and should be clear and trustworthy. Technologies such as 3D printing and smart labelling are revolutionizing food labels and packaging to meet evolving demands from consumers and the industry. A newly developed food label based on a water-soluble nanocomposite ink with a high refractive index meets quality standards and protects against counterfeiting, while also reducing waste.
See Kim et al.
Image: Younghee Lee, CUBE3D Graphic. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/Nature Food/2_1.png,MAC_Bench/Nature/Cover/Nature Food/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Food/5_9.png,MAC_Bench/Nature/Cover/Nature Food/5_9.png,groundtruth,5_9.txt,MAC_Bench/Nature/Cover/Nature Food/1_7.png,MAC_Bench/Nature/Cover/Nature Food/1_7.png,ave_2,1_7.txt,MAC_Bench/Nature/Cover/Nature Food/2_10.png,MAC_Bench/Nature/Cover/Nature Food/2_10.png,ave_3,2_10.txt,val
Nature Reviews Psychology,3_3,Which of the following options best describe the cover story?,"In this Review, Fawcett et al. describe intentional and unintentional forgetting in laboratory and real-world settings.
Cover design: David Johnston",C,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,vith,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_5.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_3.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_3.png,groundtruth,3_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,vitg,1_8.txt,train
Trends in Cell Biology,34_2,Which of the following options best describe the cover story?,"Splicing kinetics are an important aspect of splicing and have a vital
role in shaping the resulting splice isoforms present in mature RNA. Merens and
colleagues review recent advancements in analyzing pre-mRNA splicing kinetics
and methodologies for measuring intron excision rates in vivo. Understanding these
kinetics is essential for elucidating intron removal mechanisms and splicing's role
in
gene regulation. Over the past decade, various approaches have generated differing
results, leading to some controversy. This review summarizes the advantages and
limitations of these methods and explores ways to reconcile these discrepancies.
Cover design by BSIP",C,MAC_Bench/Cell/Cover/Trends in Cell Biology/21_9.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/21_9.png,vitg,21_9.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_4.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_4.png,clip,34_4.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_2.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_2.png,groundtruth,34_2.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_11.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_11.png,ave_1,23_11.txt,train
Biomacromolecules,2024_8,Which of the following options best describe the cover story?,"An investigation of methods to engineer the porosity of smart poly(N-isopropylacrylamide) (PNIPAAm) hydrogels for use as VOC-sensing elements in gaseous environments: The use of a porogen (polyethylene glycol) and freeze-drying procedures is crucial for achieving stable porous structures. The approach can be applied to other hydrogel materials and, therefore, can contribute to the expansion of use cases toward gaseous environments.",D,MAC_Bench/ACS/Cover/Biomacromolecules/2019_4.png,MAC_Bench/ACS/Cover/Biomacromolecules/2019_4.png,clip,2019_4.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2019_6.png,MAC_Bench/ACS/Cover/Biomacromolecules/2019_6.png,vitg,2019_6.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2023_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2023_10.png,vith,2023_10.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_8.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_8.png,groundtruth,2024_8.txt,test
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_4,Which of the following options best describe the cover story?,"‘Optical resolution’, inspired by the Viewpoint on super-resolution microscopy on p677
Cover design: Vicky Summersby",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/16_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/16_1.png,vith,16_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_9.png,vitg,25_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_8.png,clip,15_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_4.png,groundtruth,25_4.txt,test
Molecular Pharmaceutics,2024_1,Which of the following options best describe the cover story?,"Highlighting the broad range of high-quality work led by early career scientists (≤ 10 years from PhD) in pharmaceutical sciences and drug delivery publishing in the journal, Molecular Pharmaceutics is pleased to present a Virtual Special Issue titled “Pharmaceutical Sciences and Drug Delivery Research from Early Career Scientists”. Within this VSI, the Guest Editors have collected a wide range of articles that spotlight the breadth of research by young researchers.  An accompanying editorial by the Guest Editors provides context and commentary to accompany the VSI.",A,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_1.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_5.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_5.png,vitg,2022_5.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2023_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2023_4.png,ave_2,2023_4.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,clip,2020_4.txt,train
ACS Energy Letters,2024_4,Which of the following options best describe the cover story?,"CO2 electrolysis offers a sustainable path to generate chemicals and fuels from contaminant greenhouse gas and clean energy, and thus, to displace fossil fuels and to reduce the global carbon footprint. Several initiatives are scaling up CO2 electroreduction technology into large implementations targeting different end-products, from chemical precursors for manufacturing to jet fuels.",A,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_4.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2020_7.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2020_7.png,ave_2,2020_7.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2018_11.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2018_11.png,clip,2018_11.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2019_12.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2019_12.png,ave_1,2019_12.txt,train
ACS Applied Engineering Materials,2025_1,Which of the following options best describe the cover story?,"Two-way shape memory alloy wideband reconfigurable compound antenna using double spiral technology thermally actuating between its flat state and extended (conical) state to optimize its radio-frequency performance between satellite communication signals and telecommunication signals: This is accurately showing the functionality of the antenna, as no other direct moving parts are needed for the antenna to change states.",D,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,ave_2,2024_8.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,ave_3,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_1.png,groundtruth,2025_1.txt,train
Trends in Parasitology,40_1,Which of the following options best describe the cover story?,"The cover shows the circumsporozoite protein (CSP, cyan) and nuclei
(magenta) during the final stage of Plasmodium sporozoite formation within oocysts at the
Anopheles mosquito midgut. The image is a projection over five layers acquired from
a
4x expanded midgut with a Zeiss Airyscan 2 LSM900 microscope. In this issue of Trends
   in Parasitology, Singer et al. discuss the many roles of CSP, from sporozoite formation
within the mosquito to infection of the mammalian host. Image credit: Maren Gehringer
and Kevin Walz, Heidelberg University Medical Faculty.",B,MAC_Bench/Cell/Cover/Trends in Parasitology/34_5.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_5.png,clip,34_5.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_1.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_1.png,groundtruth,40_1.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/36_7.png,MAC_Bench/Cell/Cover/Trends in Parasitology/36_7.png,vith,36_7.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_2.png,vitg,40_2.txt,train
Current Biology,35_1,Which of the following options best describe the cover story?,"On the cover: A little devil frog (Oophaga sylvatica) rests on a leaf on the Ecuadorian rainforest floor. These frogs, like other poison
frogs, sequester alkaloids from their diet of arthropods onto their skin as a defense
against predation. In this issue, Caty et al. demonstrate that these alkaloids also shape the resident skin microbial community
of these frogs. The presence of alkaloids results in a more diverse microbial community,
both taxonomically and metabolically. Photograph © Stephanie Caty; used with permission.",C,MAC_Bench/Cell/Cover/Current Biology/35_3.png,MAC_Bench/Cell/Cover/Current Biology/35_3.png,vith,35_3.txt,MAC_Bench/Cell/Cover/Current Biology/29_2.png,MAC_Bench/Cell/Cover/Current Biology/29_2.png,clip,29_2.txt,MAC_Bench/Cell/Cover/Current Biology/35_1.png,MAC_Bench/Cell/Cover/Current Biology/35_1.png,groundtruth,35_1.txt,MAC_Bench/Cell/Cover/Current Biology/20_23.png,MAC_Bench/Cell/Cover/Current Biology/20_23.png,ave_3,20_23.txt,train
Crystal Growth & Design,2024_20,Which of the following options best describe the cover story?,"The patterns on the conveyor belt on the cover represent the four ALD growth schemes mentioned in the text, namely, ""The one step ALD method for growing TMD films"", ""PE-ALD growth of TMD films"", ""ALD selective growth patterns"", and ""The two-step ALD method for growing TMD films"".",D,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_8.png,clip,2017_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_7.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_7.png,vith,2024_7.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_2.png,vitg,2016_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_20.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_20.png,groundtruth,2024_20.txt,val
Acta Pharmacologica Sinica,45_2,Which of the following options best describe the cover story?,"Cover Credit: Urolithin A, as a fruit-derived natural product, protects against atherosclerotic plaque vulnerability by pleiotropic mechanisms, including promoting NO production, inhibiting YAP/TAZ-dependent endothelial inflammation as well as lowering lipid levels. Doi:10.1038/s41401-024-01317-5. See the article in pages 2277–2289",D,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_10.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_10.png,clip,43_10.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_3.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_3.png,vith,45_3.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_9.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_9.png,vitg,42_9.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_2.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_2.png,groundtruth,45_2.txt,train
ACS Applied Engineering Materials,2024_3,Which of the following options best describe the cover story?,View the article.,C,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_3.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_3.png,vitg,2023_3.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_1.png,clip,2025_1.txt,train
Cell Chemical Biology,31_13,Which of the following options best describe the cover story?,"On the cover: Proximity-induced chemistry is a relatively new technique for developing
protein therapeutics. Cheng et al. provide an overview of the chemical mechanisms and approaches associated with proximity-induced
chemistry. They also present innovative protein drugs developed using this technique
and discuss their therapeutic effectiveness based on pre-clinical and clinical investigations.
The cover symbolizes two proteins (blue and green surface representation) that react
to form a covalent bond in close proximity and ultimately serve as a powerful drug.
Image courtesy of the authors.",D,MAC_Bench/Cell/Cover/Cell Chemical Biology/22_10.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/22_10.png,vitg,22_10.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/21_7.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/21_7.png,clip,21_7.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_6.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_6.png,vith,18_6.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_13.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_13.png,groundtruth,31_13.txt,train
Trends in Cell Biology,34_10,Which of the following options best describe the cover story?,"Lysosomes degrade macromolecules through about 70 soluble
hydrolytic enzymes that are transported from the Golgi to lysosomes in a mannose
6-phosphate-dependent process. On pages 198–210 in this issue, Braulke et al. review
lysosomal enzyme trafficking pathways and their significance for human diseases.
The cover image shows a 3D reconstruction of electron microscopy sections from
LYSET-deficient cells, which lack the mannose 6-phosphate pathway and accumulate
undigested storage material in lysosomes (digitally colored). Cover image from
Michaela Schweizer and Rudolph Reimer.",A,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_10.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_10.png,groundtruth,34_10.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/19_4.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/19_4.png,vitg,19_4.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/21_11.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/21_11.png,clip,21_11.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_9.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_9.png,vith,29_9.txt,train
Nature Structural & Molecular Biology,31_7,Which of the following options best describe the cover story?,"A proteomics atlas of citrullination
Rebak et al. use proteomics to establish an expansive atlas of protein citrullination and implicate certain citrullinated sites as potentially clinically relevant in rheumatoid arthritis. Citrulline was initially discovered in watermelons.
See Rebak et al.
Image: THEPALMER / E+ / Getty images. Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_12.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_12.png,clip,28_12.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_7.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_7.png,groundtruth,31_7.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_9.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_9.png,vith,30_9.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_4.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_4.png,vitg,30_4.txt,train
ACS Applied Electronic Materials,2025_4,Which of the following options best describe the cover story?,"This illustration depicts a thermoelectric device designed to convert thermal energy gradients into electricity. Highlighted is the nanocomposition nature of the material, that employs CuFeS2, FeS2, and Cu2S sulfide-based materials. The images were enhanced using AI assistance from ChatGPT.",D,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2020_8.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2020_8.png,vith,2020_8.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2019_10.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2019_10.png,clip,2019_10.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2021_6.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2021_6.png,ave_2,2021_6.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_4.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_4.png,groundtruth,2025_4.txt,train
Nature Electronics,7_10,Which of the following options best describe the cover story?,"An elemental nonlinear Hall effect
Thin films of the element bismuth — an environmentally friendly and scalable material — can exhibit a tunable room-temperature nonlinear Hall effect, which could be of use in the development of optoelectronic devices. The scanning electron microscopy image on the cover shows a bismuth Hall cross device, which is used to explore magnetotransport and the nonlinear Hall effect in the polycrystalline thin films.
See Makushko et al. and News & Views by Belosevich et al.
Image: © HZDR. Cover design: Lauren Heslop.",C,MAC_Bench/Nature/Cover/Nature Electronics/4_7.png,MAC_Bench/Nature/Cover/Nature Electronics/4_7.png,vitg,4_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/1_7.png,MAC_Bench/Nature/Cover/Nature Electronics/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_10.png,MAC_Bench/Nature/Cover/Nature Electronics/7_10.png,groundtruth,7_10.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_3.png,MAC_Bench/Nature/Cover/Nature Electronics/7_3.png,vith,7_3.txt,train
Nature Synthesis,3_11,Which of the following options best describe the cover story?,"A retrosynthetic approach for nanoparticles
Retrosynthetic analysis is used for the synthesis of high-entropy alloy nanoparticles. The strategy involves the design and synthesis of core–shell nanoparticle precursors which are annealed, giving the desired alloy.
See Kar et al.
Image: Ella Maru Studio. Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/Nature Synthesis/1_5.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_5.png,vitg,1_5.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_11.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_11.png,groundtruth,3_11.txt,MAC_Bench/Nature/Cover/Nature Synthesis/4_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/4_1.png,clip,4_1.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,vith,3_9.txt,test
Inorganic Chemistry,2025_6,Which of the following options best describe the cover story?,"Co-encapsulating ligands can facilitate tunable chemistry by bringing metals together. This cover, depicting a racing circuit, conveys the excitement of clocking both ligand and metal performance. As the associated paper shows, in this chemical race, acyclic ligands and trivalent cations are high performers. The cover was prepared with Adobe Illustrator and MidJourney.",B,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_27.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_27.png,clip,2023_27.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_6.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_40.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_40.png,ave_2,2024_40.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_7.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_7.png,vitg,2025_7.txt,val
Lab Animal,53_6,Which of the following options best describe the cover story?,"3Rs around the world
The past decades have seen an increase in the interest for the 3Rs – the principles of replacement, reduction and refinement in preclinical research. Several 3R centers and platforms have been established worldwide to promote the 3Rs by sharing scientific evidence, resources and training. However, many challenges remain.
See Harrison
Cover image: PCH-Vector/Getty, Marina Spence. Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Lab Animal/51_6.png,MAC_Bench/Nature/Cover/Lab Animal/51_6.png,vitg,51_6.txt,MAC_Bench/Nature/Cover/Lab Animal/52_11.png,MAC_Bench/Nature/Cover/Lab Animal/52_11.png,clip,52_11.txt,MAC_Bench/Nature/Cover/Lab Animal/53_6.png,MAC_Bench/Nature/Cover/Lab Animal/53_6.png,groundtruth,53_6.txt,MAC_Bench/Nature/Cover/Lab Animal/51_11.png,MAC_Bench/Nature/Cover/Lab Animal/51_11.png,vith,51_11.txt,train
Trends in Biochemical Sciences,49_9,Which of the following options best describe the cover story?,"The ancient oxytocin/vasopressin (OT/VP) signaling system has garnered
significant attention for its broad implications to health and disease. Particularly
within the central nervous system, its role in modulating social behavior presents
a
compelling avenue for exploration. On pages 361–377 in this issue, Perisic et al. offer a
comprehensive review of OT-VP signaling system encompassing recent advancements
and enduring obstacles. Their analysis sheds a light on the evolving landscape of
this
protein family, offering valuable insights into future directions for research. Cover
image
by Monika Perisic.",D,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_9.png,vith,45_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/39_10.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/39_10.png,clip,39_10.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,vitg,47_14.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_9.png,groundtruth,49_9.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_2,Which of the following options best describe the cover story?,"mRNA vaccines for infectious diseases, inspired by the Review on p838.
Cover design: S. Harris",A,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_2.png,groundtruth,23_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_2.png,ave_1,20_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_2.png,vith,22_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_7.png,clip,22_7.txt,test
One Earth,7_7,Which of the following options best describe the cover story?,"On the cover: This month's cover features Suze Woolf’s artwork Larger Than Life from her series of “burned tree portraits.” By realizing that a paper substrate can
be any shape, including the contour of a burned tree, Suze works on torn paper to
represent the state of the forests. The paintings are both a metaphor for and an example
of our human impact on nature: our prediliction for cooking the planet. The artwork
featured on this month's cover illustrates the topography of fire-carved layers of
lignin, from the Tripod burn on Tiffany Mountain in Washington State's Pasayten Wilderness.
The patterns reminded Suze of the swoops and swirls of '60s acid rock music posters.
Cover by Suze Woolf https://www.suzewoolf-fineart.com/, courtesy of the artist.",D,MAC_Bench/Cell/Cover/One Earth/3_6.png,MAC_Bench/Cell/Cover/One Earth/3_6.png,ave_2,3_6.txt,MAC_Bench/Cell/Cover/One Earth/2_1.png,MAC_Bench/Cell/Cover/One Earth/2_1.png,vith,2_1.txt,MAC_Bench/Cell/Cover/One Earth/4_2.png,MAC_Bench/Cell/Cover/One Earth/4_2.png,clip,4_2.txt,MAC_Bench/Cell/Cover/One Earth/7_7.png,MAC_Bench/Cell/Cover/One Earth/7_7.png,groundtruth,7_7.txt,train
Nature Plants,10_2,Which of the following options best describe the cover story?,"Genomic history of the modern rose
For more than five thousand years, roses have delighted us as ornamental and medicinal plants and as a source of natural scent. The genome assembly of a modern tetraploid rose and a genome variation map of more than two hundred accessions helps to untangle their genetic origin and domestication.
See Zhang, Z. et al.
Image: Ruihong Zeng, China Agricultural University. Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/Nature Plants/5_7.png,MAC_Bench/Nature/Cover/Nature Plants/5_7.png,vith,5_7.txt,MAC_Bench/Nature/Cover/Nature Plants/10_2.png,MAC_Bench/Nature/Cover/Nature Plants/10_2.png,groundtruth,10_2.txt,MAC_Bench/Nature/Cover/Nature Plants/8_13.png,MAC_Bench/Nature/Cover/Nature Plants/8_13.png,clip,8_13.txt,MAC_Bench/Nature/Cover/Nature Plants/10_4.png,MAC_Bench/Nature/Cover/Nature Plants/10_4.png,vitg,10_4.txt,train
Nature Chemical Biology,21_2,Which of the following options best describe the cover story?,"20 years of Nature Chemical Biology
This month, Nature Chemical Biology celebrates 20 years with a selection of pieces that highlight some landmarks in chemical biology, examine current challenges and outline future directions. The cover image depicts a gel as a representation of the foundational techniques that underpin many advances in chemical biology.
See Editorial
Image: filo / DigitalVision Vectors / Getty Images. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/16_12.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/16_12.png,vith,16_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_11.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_11.png,vitg,15_11.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_11.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_11.png,clip,13_11.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/21_2.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/21_2.png,groundtruth,21_2.txt,train
Crystal Growth & Design,2024_19,Which of the following options best describe the cover story?,Multi-stimuli-responsive polymorphic elastic organic fluorophore.,B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_5.png,clip,2018_5.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_19.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_19.png,groundtruth,2024_19.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_2.png,vith,2022_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,vitg,2019_11.txt,val
ACS Infectious Diseases,2024_12,Which of the following options best describe the cover story?,"This front cover depicts original artwork created by Tatiana Román Valenzuela and is part of the ACS-wide DEIR Cover Art program. The piece illustrates the contributions of Alice Ball, an African American chemist who developed one of the first effective treatments for Hansen’s disease, or more widely known as leprosy. Read more about what inspired Tatiana to create this artwork in the accompanying Editorial.  View the article.",A,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_12.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_3.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_3.png,vith,2018_3.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_7.png,vitg,2018_7.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_12.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_12.png,clip,2023_12.txt,train
Trends in Parasitology,40_11,Which of the following options best describe the cover story?,"The cover illustrates a child donating a finger prick blood sample containing
malaria parasites. The blood samples are processed to purify DNA that contains both
human
and parasite materials. Targeted amplification of parasite molecular markers enables
further
analysis. Molecular markers are illustrated as coloured segments distributed throughout
the DNA strand. Genotypes comprised of these markers are used to conduct population
genetic analyses to describe malaria transmission patterns. In this issue of Trends in
   Parasitology, Ruybal- Pesántez et al. review the landscape of molecular markers available
for malaria genomic surveillance and their utility according to defi ned use cases
for malaria
control. Image credit: Thorey Jonsdottir.",A,MAC_Bench/Cell/Cover/Trends in Parasitology/40_11.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_11.png,groundtruth,40_11.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/36_8.png,MAC_Bench/Cell/Cover/Trends in Parasitology/36_8.png,clip,36_8.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,vitg,34_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_5.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_5.png,vith,40_5.txt,train
Journal of Chemical Information and Modeling,2025_4,Which of the following options best describe the cover story?,"Extracting relevant structures from free energy molecular simulations can be a daunting task. The newly developed FESTA script simplifies this process, offering ease, robustness, and broad compatibility, making ""fishing"" in the free energy pond both efficient and enjoyable.",C,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_3.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_3.png,ave_1,2015_3.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2017_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2017_6.png,clip,2017_6.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_4.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2012_7.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2012_7.png,ave_2,2012_7.txt,test
Immunity,57_4,Which of the following options best describe the cover story?,"On the cover: Stroke leads to persistently high risk for recurrent vascular events
caused by systemic atheroprogression driven by endothelial cell activation. In this
issue, Liu et al. report that stroke causes persistent activation of endothelial Notch1 signaling in
the periphery. Brain-derived exosomal Notch1 ligands induce a senescent, pro-inflammatory
endothelium that drives post-stroke atheroprogression. Brain-derived exosomal Notch1
ligands are illustrated in the form of falling rocks from the top of a mountain (brain)
and atheroprogression, and the associated blood traffic congestion is depicted as
vehicles accumulating behind the block in the road. Cover image by Mingming Liu and
Qiang Liu.",D,MAC_Bench/Cell/Cover/Immunity/31_6.png,MAC_Bench/Cell/Cover/Immunity/31_6.png,clip,31_6.txt,MAC_Bench/Cell/Cover/Immunity/55_7.png,MAC_Bench/Cell/Cover/Immunity/55_7.png,vitg,55_7.txt,MAC_Bench/Cell/Cover/Immunity/48_2.png,MAC_Bench/Cell/Cover/Immunity/48_2.png,ave_1,48_2.txt,MAC_Bench/Cell/Cover/Immunity/57_4.png,MAC_Bench/Cell/Cover/Immunity/57_4.png,groundtruth,57_4.txt,train
Science Robotics,9_88,Which of the following options best describe the cover story?,"ONLINE COVER Snake-Like Robot—A Robot for Autonomous Navigation and Exploration of Icy Terrain. Vaquero et al. report on a snake-like robot, Exobiology Extant Life Surveyor (EELS), that was developed to autonomously explore icy moons such as Enceladus. EELS has a perception head containing sensors and cameras for detection of its surroundings, as well as screw-like segments that generate forward and backward motion horizontally on icy surfaces and vertically within ice vents. The robot was capable of autonomous motion planning and risk awareness. This month’s cover is an image of EELS being tested on Athabasca Glacier in Alberta, Canada. Credit: Courtesy of NASA/JPL-Caltech",B,MAC_Bench/Science/Cover/Science Robotics/2_8.png,MAC_Bench/Science/Cover/Science Robotics/2_8.png,clip,2_8.txt,MAC_Bench/Science/Cover/Science Robotics/9_88.png,MAC_Bench/Science/Cover/Science Robotics/9_88.png,groundtruth,9_88.txt,MAC_Bench/Science/Cover/Science Robotics/6_55.png,MAC_Bench/Science/Cover/Science Robotics/6_55.png,vitg,6_55.txt,MAC_Bench/Science/Cover/Science Robotics/8_85.png,MAC_Bench/Science/Cover/Science Robotics/8_85.png,vith,8_85.txt,train
ACS Chemical Neuroscience,2025_4,Which of the following options best describe the cover story?,"This cover image offers a peek at the cytosolic environment of a central nervous system (CNS) cell. It highlights the dual-action mechanism of a small molecule, which is shown to interact with both carbonic anhydrase and the mitochondrial outer membrane protein TSPO. These interactions suggest a potential therapeutic strategy targeting these proteins, which play crucial roles in CNS function. The DALL-E AI platform from OpenAI generated the background. Muhammad Waqas and Benito Natale crafted the cover.",D,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_16.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_16.png,vitg,2021_16.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_20.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_20.png,vith,2024_20.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,clip,2024_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2025_4.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2025_4.png,groundtruth,2025_4.txt,train
Cell Systems,15_1,Which of the following options best describe the cover story?,"On the cover: Illustration of immunity and vaccination. This issue of Cell Systems focuses on systems immunology and includes a variety of primary research articles,
reviews, perspectives, and short pieces on the topic. Image credit: Getty.",B,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,vith,11_2.txt,MAC_Bench/Cell/Cover/Cell Systems/15_1.png,MAC_Bench/Cell/Cover/Cell Systems/15_1.png,groundtruth,15_1.txt,MAC_Bench/Cell/Cover/Cell Systems/4_5.png,MAC_Bench/Cell/Cover/Cell Systems/4_5.png,ave_1,4_5.txt,MAC_Bench/Cell/Cover/Cell Systems/15_12.png,MAC_Bench/Cell/Cover/Cell Systems/15_12.png,clip,15_12.txt,train
Nature Reviews Nephrology,21_2,Which of the following options best describe the cover story?,"Targeting IgA nephropathy, inspired by the Review on p9
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,clip,17_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/21_2.png,groundtruth,21_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_4.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_4.png,vitg,18_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_2.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_2.png,ave_1,17_2.txt,train
ACS Catalysis,2024_3,Which of the following options best describe the cover story?,This cover art depicts the hydrolysis of polysaccharides of the cell wall or red macroalgae by enzymes of marine or gut bacteria. The mechanistic study on a neoagarosidase from Phocaeicola plebeius shows an unusual pair of amino acids that operates catalysis.,B,MAC_Bench/ACS/Cover/ACS Catalysis/2020_5.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_5.png,ave_3,2020_5.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_3.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2020_13.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_13.png,ave_2,2020_13.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2023_6.png,MAC_Bench/ACS/Cover/ACS Catalysis/2023_6.png,clip,2023_6.txt,val
ACS Sensors,2025_1,Which of the following options best describe the cover story?,This cover and Collection celebrate 10 years of ACS Sensors. View the Editorial.,D,MAC_Bench/ACS/Cover/ACS Sensors/2020_7.png,MAC_Bench/ACS/Cover/ACS Sensors/2020_7.png,vith,2020_7.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_3.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_3.png,vitg,2024_3.txt,MAC_Bench/ACS/Cover/ACS Sensors/2020_5.png,MAC_Bench/ACS/Cover/ACS Sensors/2020_5.png,clip,2020_5.txt,MAC_Bench/ACS/Cover/ACS Sensors/2025_1.png,MAC_Bench/ACS/Cover/ACS Sensors/2025_1.png,groundtruth,2025_1.txt,test
ACS Central Science,2025_2,Which of the following options best describe the cover story?,"Via synergistic photoredox/Brønsted acid catalysis, a novel three-component radical cascade reaction occurred through a radical addition/ring-opening/PCET-promoted radical–radical coupling protocol, affording an array of valuable enantioenriched",D,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,ave_2,2024_2.txt,MAC_Bench/ACS/Cover/ACS Central Science/2025_1.png,MAC_Bench/ACS/Cover/ACS Central Science/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,ave_3,2023_6.txt,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,groundtruth,2025_2.txt,train
ACS Materials Au,2024_6,Which of the following options best describe the cover story?,"High-precision printing using gold nanoparticle ink, characterized by its low-temperature sintering capacity, presents a promising frontier for advancing flexible printed and wearable electronic technologies. The cover features the investigation and optimization of a water-based gold nanoparticle ink formulation tailored for utilization in aerosol jet and inkjet printers, specifically for applications within printed electronics.",B,MAC_Bench/ACS/Cover/ACS Materials Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_4.png,clip,2022_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2024_6.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,ave_2,2024_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Materials Au/2025_1.png,ave_1,2025_1.txt,val
Nature Chemistry,17_1,Which of the following options best describe the cover story?,"Chiroptical ionic co-crystals
The co-crystallization of nanoclusters with functional organic molecules can provide access to superlattices with unique properties; however, this process remains synthetically challenging. Now, a team led by Jarad A. Mason has shown that silver nanoclusters and organic macrocycles can be assembled through a supramolecular approach into ionic co-crystals with tunable structures that exhibit large chiroptical effects. The cover shows the structure of enantiopure chiral co-crystals featuring atomically precise silver nanoclusters and organic macrocycles.
See Mason et al.
Image: Dr. Yingwei Li, Harvard University. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Chemistry/13_5.png,MAC_Bench/Nature/Cover/Nature Chemistry/13_5.png,vitg,13_5.txt,MAC_Bench/Nature/Cover/Nature Chemistry/12_1.png,MAC_Bench/Nature/Cover/Nature Chemistry/12_1.png,ave_2,12_1.txt,MAC_Bench/Nature/Cover/Nature Chemistry/15_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/15_6.png,clip,15_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/17_1.png,MAC_Bench/Nature/Cover/Nature Chemistry/17_1.png,groundtruth,17_1.txt,train
Nature Cardiovascular Research,3_4,Which of the following options best describe the cover story?,"Understanding fibromuscular dysplasia
By integrating DNA genotype and RNA-sequencing data from human samples, d’Escamard et al. identified a gene regulatory co-expression supernetwork that has an important role in fibromuscular dysplasia, a poorly understood disease affecting 3–5% of adult women, and generated a mouse model of the disease.
See d’Escamard et al.
Image: Bethany Vukomanovic. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_7.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_4.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_4.png,groundtruth,3_4.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/4_1.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/4_1.png,vitg,4_1.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_9.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_9.png,vith,2_9.txt,train
Nature Reviews Cardiology,22_2,Which of the following options best describe the cover story?,"Cardiac sarcomeric proteins, inspired by the Review on p9
Cover design: Vicky Summersby",C,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_12.png,ave_2,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_9.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_9.png,clip,19_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/22_2.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/22_2.png,groundtruth,22_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_7.png,vitg,19_7.txt,train
Nature Reviews Bioengineering,2_1,Which of the following options best describe the cover story?,"Deep generative models can generate synthetic data to tackle challenges inherent in real-world data within bioengineering and medicine. These challenges include concerns around privacy, biases in data, distributional shifts, underrepresentation of specific populations, and the scarcity of high-quality data. See Boris van Breugel et al
Cover image: Simon Bradbrook",C,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,clip,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,vith,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_1.png,groundtruth,2_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_4.png,vitg,2_4.txt,val
NATURE MATERIALS,23_11,Which of the following options best describe the cover story?,"Precise control of gas transport in metal–organic framework glasses
Porosity of zeolitic imidazolate frameworks can be preserved beyond the glass transition and melt processing. Here centimetre-scale porous glasses are demonstrated, while liquid processing enables fine-tuning of the size of the gas-transporting channels for molecular sieving.
See Smirnova et al.
Image: Oksana Smirnova, Friedrich Schiller University Jena. Cover design: Alex Whitworth",C,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_11.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_11.png,vith,19_11.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/17_8.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/17_8.png,vitg,17_8.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_11.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_11.png,groundtruth,23_11.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/3_12.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/3_12.png,clip,3_12.txt,val
Nature Chemical Biology,20_8,Which of the following options best describe the cover story?,"A checkpoint for insulin secretion
A chemical screen reveals that inhibitors of CHEK2, a checkpoint kinase, can enhance glucose-stimulated insulin secretion in human primary islets and animal models. The cover shows a confocal microscopy image of a human islet immunostained with antibodies against insulin (green), Ki67 (red) and DAPI (blue).
See Chong et al.
Image: Angie Chi Nok Chong, Weill Cornell Medicine. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_7.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_7.png,clip,17_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_12.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_12.png,vith,14_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_5.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_5.png,vitg,17_5.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_8.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_8.png,groundtruth,20_8.txt,train
Nature Catalysis,7_11,Which of the following options best describe the cover story?,"Oscillating through oxygen phases
In their work, Thomas Lunkenbein, Luis Sandoval-Diaz and colleagues study the dry reforming of methane on a nickel catalyst with in situ techniques, which reveal oscillatory kinetics through atomic surface oxygen, subsurface oxygen and bulk nickel oxide phases, with markedly different catalytic properties.
See Sandoval-Diaz et al.
Image: MPG-FHI/Luis Sandoval-Diaz. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/Nature Catalysis/7_11.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_11.png,groundtruth,7_11.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_10.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_10.png,clip,7_10.txt,MAC_Bench/Nature/Cover/Nature Catalysis/3_2.png,MAC_Bench/Nature/Cover/Nature Catalysis/3_2.png,vith,3_2.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_3.png,vitg,7_3.txt,test
ACS Medicinal Chemistry Letters,2025_1,Which of the following options best describe the cover story?,"PROTACs: a matter of vector. Two PROTACs based on the same BAZ2A/BAZ2B bromodomain ligand and linker differ only by attachment point to the VHL ligand. Albeit subtle, this difference is crucial: dBAZ2 (blue) degrades both BAZ2A and BAZ2B, while dBAZ2B (orange) is a BAZ2B-selective degrader.",C,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_9.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_9.png,ave_3,2017_9.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_1.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_4.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_4.png,ave_2,2017_4.txt,train
Bioconjugate Chemistry,2024_9,Which of the following options best describe the cover story?,Utilization of metal-free click chemistry provides a green approach to fabricate functional hydrogels for biomedical applications.,B,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_5.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_5.png,vith,2016_5.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_9.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_5.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,vitg,2013_2.txt,train
Nature Reviews Bioengineering,2_5,Which of the following options best describe the cover story?,"Brain-machine interfaces can be connected to the nervous system to decode neural signals and translate them into commands for the control of external devices, for example, to enable individuals with paralysis to restore movements. However, long-term stability and wireless transmission of neural data remain challenging. In addition, issues of hype, patient access, user-centred design and long-term support will need to be addressed. See reality check of brain-machine interfaces
Cover image: Simon Bradbrook",B,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_4.png,clip,2_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_5.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_5.png,groundtruth,2_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_1.png,ave_2,2_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_3.png,ave_3,1_3.txt,train
Chem & Bio Engineering,2024_11,Which of the following options best describe the cover story?,"Remarkable antimalarial activity of the extract of Artemisia annua L. obtained with salicylate salts and ionic liquids: The extract contains artemisinin but also artemitin, chrysosplenol D, arteannuin B, and arteannuin J, which synergistically enhance the antimalarial activity.",A,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_11.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,ave_2,2024_6.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,vith,2024_7.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,clip,2024_4.txt,train
Nano Letters,2025_8,Which of the following options best describe the cover story?,"The cover art depicts a microtubule structure with intact and open segments exposing the inner surface. Atomic force microscopy reveals a high-resolution view, showing an undulating arrangement of protofilaments (PFs) with alternating height variations, caused by different structural orientations and conformations of αβ-tubulin dimers in adjacent PFs.",A,MAC_Bench/ACS/Cover/Nano Letters/2025_8.png,MAC_Bench/ACS/Cover/Nano Letters/2025_8.png,groundtruth,2025_8.txt,MAC_Bench/ACS/Cover/Nano Letters/2015_5.png,MAC_Bench/ACS/Cover/Nano Letters/2015_5.png,ave_0,2015_5.txt,MAC_Bench/ACS/Cover/Nano Letters/2023_3.png,MAC_Bench/ACS/Cover/Nano Letters/2023_3.png,clip,2023_3.txt,MAC_Bench/ACS/Cover/Nano Letters/2015_2.png,MAC_Bench/ACS/Cover/Nano Letters/2015_2.png,vith,2015_2.txt,train
Acta Pharmacologica Sinica,45_1,Which of the following options best describe the cover story?,"Cover Credit: Diagram of the proposed mechanisms by which CEMIP reduces the chemotherapy sensitivity of SCLC cells. CEMIP, an adaptor protein, interacts with SRC and YAP. CEMIP binds to SRC, allowing autophosphorylation of Y416 and activation of SRC, which facilitates the interaction between YAP and activated SRC, resulting in increased phosphorylation of Y357, protein stability, nuclear accumulation and transcriptional activation of YAP,thus reducing the chemotherapeutic sensitivity of SCLC cells. The SRC inhibitor dasatinib and the YAP inhibitor verteporfin display synergistic antitumor effects on SCLC both in vitro and in vivo. (DOI 10.1038/s41401-024-01342-4). See the article in pages 2657–2671",A,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_1.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_1.png,groundtruth,45_1.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_2.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_2.png,clip,41_2.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_6.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_6.png,vith,45_6.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_10.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_10.png,vitg,44_10.txt,train
Science Signaling,2007_412,Which of the following options best describe the cover story?,"COVER This week features a  Review on the mechanisms by which the PAR1 and SIP1 receptors regulate endothelial adherens junction integrity. The image depicts an adherens junction. [Image: Preston Huey, AAAS]",C,MAC_Bench/Science/Cover/Science Signaling/14_671.png,MAC_Bench/Science/Cover/Science Signaling/14_671.png,clip,14_671.txt,MAC_Bench/Science/Cover/Science Signaling/2_65.png,MAC_Bench/Science/Cover/Science Signaling/2_65.png,vitg,2_65.txt,MAC_Bench/Science/Cover/Science Signaling/2007_412.png,MAC_Bench/Science/Cover/Science Signaling/2007_412.png,groundtruth,2007_412.txt,MAC_Bench/Science/Cover/Science Signaling/5_233.png,MAC_Bench/Science/Cover/Science Signaling/5_233.png,vith,5_233.txt,train
Nature Physics,20_1,Which of the following options best describe the cover story?,"No heat flow in ground-state graphene
The ground state of electrons in undoped graphene at high magnetic field is still not fully known. Measurements of thermal conductance could help to differentiate between the various theoretically proposed candidates. Delagrange et al. report such measurements and find that the thermal conductivity is vanishingly small, in contradiction to many of the predictions.
See Delagrange et al.
Image: Francois Parmentier, SPEC – CNRS UMR3680. Cover design: Laoise Mac Gabhann",C,MAC_Bench/Nature/Cover/Nature Physics/15_4.png,MAC_Bench/Nature/Cover/Nature Physics/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/Nature Physics/20_8.png,MAC_Bench/Nature/Cover/Nature Physics/20_8.png,vith,20_8.txt,MAC_Bench/Nature/Cover/Nature Physics/20_1.png,MAC_Bench/Nature/Cover/Nature Physics/20_1.png,groundtruth,20_1.txt,MAC_Bench/Nature/Cover/Nature Physics/16_12.png,MAC_Bench/Nature/Cover/Nature Physics/16_12.png,clip,16_12.txt,train
ACS Catalysis,2024_7,Which of the following options best describe the cover story?,"CO2 is catalytically hydrogenated to methanol at the active interface sites between the highly dispersed gallium clusters and the In2O3 support, while Ga2O3 nanoparticles inhibit the adsorption and dissociation of H2, resulting in increased CO by-product.",D,MAC_Bench/ACS/Cover/ACS Catalysis/2015_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2015_11.png,vitg,2015_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2022_21.png,MAC_Bench/ACS/Cover/ACS Catalysis/2022_21.png,clip,2022_21.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2021_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2021_11.png,vith,2021_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_7.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_7.png,groundtruth,2024_7.txt,val
ACS ES&T Engineering,2024_3,Which of the following options best describe the cover story?,Deciphering biological aerosol particles in the atmosphere is a challenging task. Single particle analysis of morphology and chemical composition of particles combined with advanced supervised machine learning techniques can improve detection of primary biological aerosol particles in the atmosphere.,D,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_12.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_12.png,vith,2024_12.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_6.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_6.png,clip,2022_6.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_3.png,groundtruth,2024_3.txt,test
Nature Reviews Psychology,3_9,Which of the following options best describe the cover story?,"Sounds are generated by interactions between objects in the world. In this Review, Winkler & Denham describe how representations of sources and actions enable humans to segment complex auditory experience into meaningful units.
Cover design: David Johnston",A,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_9.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_9.png,groundtruth,3_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,ave_2,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_11.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_11.png,clip,1_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_6.png,ave_3,1_6.txt,train
Joule,8_11,Which of the following options best describe the cover story?,"On the cover: Zhang et al. develop a universal encapsulation method for commercialized perovskite solar cell
(PSC). The encapsulated PSC modules passed outdoor stability, UV preconditioning,
and hail tests according to the International Electrotechnical Commission 61215 standard.
Image credit: Guodong Zhang, Yifan Zheng, and Yuchuan Shao.",B,MAC_Bench/Cell/Cover/Joule/8_7.png,MAC_Bench/Cell/Cover/Joule/8_7.png,vith,8_7.txt,MAC_Bench/Cell/Cover/Joule/8_11.png,MAC_Bench/Cell/Cover/Joule/8_11.png,groundtruth,8_11.txt,MAC_Bench/Cell/Cover/Joule/6_12.png,MAC_Bench/Cell/Cover/Joule/6_12.png,clip,6_12.txt,MAC_Bench/Cell/Cover/Joule/8_9.png,MAC_Bench/Cell/Cover/Joule/8_9.png,vitg,8_9.txt,val
Nature Nanotechnology,19_9,Which of the following options best describe the cover story?,"Nanobots for radionuclide bladder cancer therapy
The cover image shows a three-dimensional reconstruction of a mouse bladder affected by a prominent tumour, with urease-powered nanobots targeting the tumour.
See Simó et al.
Image: Julien Colombelli, Institute for Research in Biomedicine (IRB Barcelona). Cover design: Valentina Monaco",C,MAC_Bench/Nature/Cover/Nature Nanotechnology/14_9.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/14_9.png,vith,14_9.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/9_4.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/9_4.png,vitg,9_4.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_9.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_9.png,groundtruth,19_9.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,val
Nature Chemical Biology,20_2,Which of the following options best describe the cover story?,"Phasing in physicochemical features
Phase transitions give rise to macromolecular assemblies at a distinct physical scale, encoding functions that surpass those of their individual molecular constituents. This image illustrates the emerging electrochemistry of biomolecular condensates.
See Wang et al.
Image: Hualin Ou and Yifan Dai, Washington University in St. Louis. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/16_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/16_4.png,vitg,16_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_3.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_3.png,clip,20_3.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,vith,17_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_2.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_2.png,groundtruth,20_2.txt,train
Trends in Biotechnology,42_2,Which of the following options best describe the cover story?,"In pages 1523–1532 of this issue, Yuan and colleagues present a 3D,
spatially resolved model of breast cancer that highlights locally differentiated responses
to chemotherapy. The cover image blends traditional Chinese elements with modern
3D printing technology. The red and green nozzles are used to print the cancer cell-rich
region and the stroma region. In the summer pond, which represents the bioprinted
tumor microenvironment model, two green lotus flowers of different sizes are set within,
symbolizing varying-sized dense regions of cancer cells. The surrounding red branching
structures and purple polygons resemble koi fish swimming in the water, representing
the microvessel-rich stroma. The lotus petals spreading outward symbolize the tumor
cells migrating into the stroma. Cover image from Shanghai Mu Mu Chuang Cultural
Communication Co., Ltd.",B,MAC_Bench/Cell/Cover/Trends in Biotechnology/33_4.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/33_4.png,vith,33_4.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_2.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_2.png,groundtruth,42_2.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_6.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_6.png,clip,42_6.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_8.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_8.png,vitg,42_8.txt,train
ACS Chemical Neuroscience,2024_14,Which of the following options best describe the cover story?,"Ketone bodies are mainly synthesized in the mitochondria of hepatocytes in the liver. Remote ischemic post-conditioning stimulates the liver to produce large quantities of ketone bodies, primarily acetoacetate and",C,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2016_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2016_10.png,clip,2016_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_5.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_5.png,vitg,2021_5.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2014_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2014_6.png,vith,2014_6.txt,train
ACS Central Science,2024_11,Which of the following options best describe the cover story?,"Unlocking the potential of broccoli in thrombolysis treatment: Our research shows that sulforaphane, a naturally occurring isothiocyanate in broccoli, significantly enhances the efficacy of clot-busting therapies in treating carotid artery occlusions. This finding paves a new way for incorporating nutritional elements into thrombolysis treatments, potentially revolutionizing stroke care and management.",A,MAC_Bench/ACS/Cover/ACS Central Science/2024_11.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_9.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_9.png,vitg,2023_9.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_12.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_12.png,clip,2024_12.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_8.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_8.png,ave_2,2023_8.txt,train
Journal of the American Chemical Society,2024_18,Which of the following options best describe the cover story?,This work reveals an epitaxy-like conversion reaction mechanism through electrochemical intercalation chemistry. This illustration depicts the self-evolved robust layer-interlaced nanostructure of an R3m-type bismuth electrode for hosting chlorine.  View the article.,D,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_16.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_16.png,ave_1,2017_16.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_47.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_47.png,clip,2011_47.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_42.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_42.png,vitg,2016_42.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_18.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_18.png,groundtruth,2024_18.txt,train
Biomacromolecules,2024_6,Which of the following options best describe the cover story?,Exploring novel natural cryoprotectant and its antifreeze mechanism allows the rational design of future sustainable antifreeze analogs. The current study isolated different antifreeze polysacchar,C,MAC_Bench/ACS/Cover/Biomacromolecules/2024_3.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_3.png,ave_2,2024_3.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2020_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2020_10.png,vith,2020_10.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_6.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2023_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2023_10.png,clip,2023_10.txt,train
Nature Climate Change,14_9,Which of the following options best describe the cover story?,"Losing meteorites
Most of the meteorites in today's collections have been found in Antarctica, making it a key region for planetary science. Writing in this issue, Tollenaar, Zekollari and colleagues show that surface melt due to climate change can lead to substantial portions of current meteorites sinking into the ice, leaving bare blue ice areas void of any of these precious space rocks, making them unavailable for science.
See Tollenaar  et al. and News & Views by Righter
Image: Veronica Tollenaar, Université libre de Bruxelles. Cover design: Valentina Monaco",B,MAC_Bench/Nature/Cover/Nature Climate Change/8_1.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_1.png,ave_2,8_1.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_9.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_9.png,groundtruth,14_9.txt,MAC_Bench/Nature/Cover/Nature Climate Change/9_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/9_10.png,clip,9_10.txt,MAC_Bench/Nature/Cover/Nature Climate Change/8_5.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_5.png,vitg,8_5.txt,train
Journal of Agricultural and Food Chemistry,2025_5,Which of the following options best describe the cover story?,Schiff-base-mediated egg white peptide supramolecular self-assembly could serve as robust curcumin carriers for significantly enhancing its transport in intestinal epithelial cells via endocytosis while inhibiting P-glycoprotein-mediated cellular efflux.,C,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2023_20.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2023_20.png,vitg,2023_20.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2022_48.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2022_48.png,clip,2022_48.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_5.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_4.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_4.png,vith,2025_4.txt,train
Trends in Cell Biology,34_7,Which of the following options best describe the cover story?,"Noncoding variants are thought to be responsible for the vast majority
of our genetic predisposition to disease. Unlike coding variants, which disrupt amino
acid sequences, noncoding variants often disrupt transcription factor binding motifs
and alter gene regulation and gene expression. On pages 465-483 in this issue, Chin
&
Gardell et al. review the current state of noncoding variant prioritization and validation.
They highlight the challenges associated with obtaining definitive proof of noncoding
variant effects and suggest a workflow that provides the groundwork to move beyond
association and towards genetically informed studies on the molecular and cellular
mechanisms of polygenic diseases. Cover design by Cathrine Petersen.",A,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_7.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_7.png,groundtruth,34_7.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_1.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_1.png,vitg,34_1.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_1.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_1.png,vith,29_1.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_4.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_4.png,clip,34_4.txt,train
Accounts of Materials Research,2025_1,Which of the following options best describe the cover story?,"Metal–organic frameworks featuring well-defined active sites enable efficient activation and conversion of methane, promoting sustainable production of value-added chemicals.",C,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_5.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_5.png,clip,2023_5.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_6.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2025_1.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_1.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_1.png,vitg,2021_1.txt,train
Science Signaling,2007_400,Which of the following options best describe the cover story?,"COVER This week's Focus Issue on cell migration features an Editorial Guide, as well as a Perspective, a Review, and a Protocol. The image depicts a cell extending a pseudopod toward a chemoattractant. [Image: Preston Huey, AAAS]",D,MAC_Bench/Science/Cover/Science Signaling/1_30.png,MAC_Bench/Science/Cover/Science Signaling/1_30.png,vitg,1_30.txt,MAC_Bench/Science/Cover/Science Signaling/8_366.png,MAC_Bench/Science/Cover/Science Signaling/8_366.png,vith,8_366.txt,MAC_Bench/Science/Cover/Science Signaling/16_797.png,MAC_Bench/Science/Cover/Science Signaling/16_797.png,clip,16_797.txt,MAC_Bench/Science/Cover/Science Signaling/2007_400.png,MAC_Bench/Science/Cover/Science Signaling/2007_400.png,groundtruth,2007_400.txt,test
Science Signaling,2007_404,Which of the following options best describe the cover story?,COVER This week features a  Perspective on regulation of nitric oxide synthase by β-actin. The image depicts a single monomer of β-actin. [Image based on PDB 2oan],B,MAC_Bench/Science/Cover/Science Signaling/2_63.png,MAC_Bench/Science/Cover/Science Signaling/2_63.png,vith,2_63.txt,MAC_Bench/Science/Cover/Science Signaling/2007_404.png,MAC_Bench/Science/Cover/Science Signaling/2007_404.png,groundtruth,2007_404.txt,MAC_Bench/Science/Cover/Science Signaling/5_250.png,MAC_Bench/Science/Cover/Science Signaling/5_250.png,vitg,5_250.txt,MAC_Bench/Science/Cover/Science Signaling/2007_414.png,MAC_Bench/Science/Cover/Science Signaling/2007_414.png,clip,2007_414.txt,train
Nature Reviews Neurology,20_12,Which of the following options best describe the cover story?,"Overlapping phenotypes, inspired by the Review on p7.
Cover design: Philip Patenall",A,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_12.png,groundtruth,20_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_2.png,vitg,18_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_11.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_11.png,vith,18_11.txt,train
BDJ In Practice,37_4,Which of the following options best describe the cover story?,"In this issue...
September's cover feature asks whether paediatric patients are harder to reach than ever before
Cover illustration by Tim Marrs",B,MAC_Bench/Nature/Cover/BDJ In Practice/36_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_2.png,ave_1,36_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_4.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_4.png,groundtruth,37_4.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,ave_2,37_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/34_12.png,MAC_Bench/Nature/Cover/BDJ In Practice/34_12.png,clip,34_12.txt,train
Nature Biomedical Engineering,8_3,Which of the following options best describe the cover story?,"An immunosuppressive subcutaneous niche for treating ulcerative colitis
This issue highlights an injectable zwitterionic gel that can be applied to the tip of insulin-infusion catheters, week-long normoglycaemia in diabetic mice and minipigs via glucose-responsive insulin, subcutaneous biodegradable scaffolds for restimulating the antitumour activity of pre-administered CAR T cells, an injectable subcutaneous colon-specific immune niche for the treatment of ulcerative colitis, subcutaneous neovascularization for the long-term survival of encapsulated islets without immunosuppression, prevention of peri-implant fibrosis by functionally inhibiting skeletal cells expressing the leptin receptor, and the discovery of immunometabolic cues reprogramming the microenvironment around implanted biomaterials.
The cover illustrates an injectable subcutaneous colon-specific niche consisting of colon epithelial cells, decellularized colon extracellular matrix and immunosuppressive nanofibres.
See Au et al.
Image: Ella Maru Studio. Cover design: Alex Wing.",A,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_3.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_3.png,groundtruth,8_3.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_8.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_8.png,clip,4_8.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/2_2.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/2_2.png,vith,2_2.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/1_5.png,ave_2,1_5.txt,train
Cell Reports,43_11,Which of the following options best describe the cover story?,"On the cover: In this issue, Jiang et al. show high plasticity of ribosomal DNA organization using a synthetic rDNA array in
budding yeast. The cover image depicts a yeast cell, with tandemly repeated rDNA sequences
forming a nucleolar organizing region (shown in blue). The magnified rDNA sequences
contain recognition sites for the Cre enzyme (in red) that upon recognition are cleaved,
leading to simplification of the rDNA region. Image credit to Shuangying Jiang and
Zelin Cai, with input from Cheng Zeng and Yun Wang.",B,MAC_Bench/Cell/Cover/Cell Reports/24_5.png,MAC_Bench/Cell/Cover/Cell Reports/24_5.png,vitg,24_5.txt,MAC_Bench/Cell/Cover/Cell Reports/43_11.png,MAC_Bench/Cell/Cover/Cell Reports/43_11.png,groundtruth,43_11.txt,MAC_Bench/Cell/Cover/Cell Reports/1_2.png,MAC_Bench/Cell/Cover/Cell Reports/1_2.png,clip,1_2.txt,MAC_Bench/Cell/Cover/Cell Reports/28_4.png,MAC_Bench/Cell/Cover/Cell Reports/28_4.png,vith,28_4.txt,train
Industrial & Engineering Chemistry Research,2024_7,Which of the following options best describe the cover story?,"An overview of chemical reactions activated by plasma, including oxidation, reduction, copolymerization and polymerization, elimination, addition, isomerization, and rearrangement reactions.",A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_7.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_13.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_13.png,clip,2022_13.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_45.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_45.png,ave_2,2018_45.txt,val
Nature Reviews Neurology,20_6,Which of the following options best describe the cover story?,"Brain asymmetries, inspired by the Review on p383.
Cover design: S. Whitham",A,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,groundtruth,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_11.png,ave_3,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_10.png,vitg,19_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,clip,19_2.txt,val
Cell Reports Methods,4_10,Which of the following options best describe the cover story?,"On the cover: In this issue, Shinde et al. present CMI-PB, a data resource and challenge contest to develop computational models
predicting vaccine responses. The cover image draws inspiration from the “blind man
and elephant” parable, showing blindfolded scientists each bringing their own expertise
to solve a multifaceted systems biology problem represented by the elephant and involving
the multi-omics datatypes represented at the top. Courtesy: Unsplash (Wolfgang Hasselmann)
and BioRender.",B,MAC_Bench/Cell/Cover/Cell Reports Methods/1_1.png,MAC_Bench/Cell/Cover/Cell Reports Methods/1_1.png,vitg,1_1.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_10.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_10.png,groundtruth,4_10.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_8.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_8.png,vith,2_8.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_3.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_3.png,clip,3_3.txt,train
The Journal of Organic Chemistry,2025_1,Which of the following options best describe the cover story?,Ruthenium-catalyzed novel (Z)-3-ferrocenylideneisobenzofuran-1(3H)-one compounds were synthesized by the ortho-CH activation of benzoic acid and ferrocenyl styrene in the presence of green solvent water. Exploring the transformation of benzoic acid and styrene into crude products leads to transformation into bioactive compounds 1,B,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2022_9.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2022_9.png,clip,2022_9.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_1.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2016_21.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2016_21.png,vith,2016_21.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2022_20.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2022_20.png,vitg,2022_20.txt,train
Nature Reviews Endocrinology,20_10,Which of the following options best describe the cover story?,"Health equity in endocrinology, inspired by the Viewpoint on p130.
Cover design: Jennie Vallis",C,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,vith,18_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/14_11.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/14_11.png,vitg,14_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_10.png,groundtruth,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_3.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_3.png,clip,17_3.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_11,Which of the following options best describe the cover story?,"Looking back on 2023, inspired by the Year in Reviews starting on p72.
Cover design: Laura Marshall.",B,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_9.png,vith,20_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_11.png,groundtruth,21_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_12.png,vitg,20_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_7.png,clip,21_7.txt,test
Nature Reviews Cardiology,21_11,Which of the following options best describe the cover story?,"High altitude physiology, inspired by the Review on p75.
Cover design: Vicky Summersby",D,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_4.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_4.png,vitg,18_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_2.png,clip,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_9.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_9.png,vith,18_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_11.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_11.png,groundtruth,21_11.txt,train
Trends in Pharmacological Sciences,45_3,Which of the following options best describe the cover story?,"Recent studies have shed more light on the pivotal role of transient
receptor potential melastatin (TRPM) channels in the pathophysiology of cerebral
ischemia-reperfusion (I/R) injury. In this issue, Liu et al. summarize the recent
understanding of the role of TRPM channels in cerebral I/R injury, focusing on their
contribution to oxidative stress, mitochondrial dysfunction, inflammatory responses,
and calcium overload. They also discuss challenges and future directions in
therapeutically targeting TRPM channels in cerebral I/R injury. The cover is an
illustration of TRPM 2, 4, 7 and 8 (yellow, green, pink and blue). Cells impacted
such
as neuron (blue), microglia and astrocyte (yellow) are also depicted. Other elements
depicted are activated inflammasome, degenerating myelin sheat, and misfolded
proteins (brown), features in some cerebral I/R injury. Cover designed by Hong Xi
using BioRender.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/36_6.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/36_6.png,clip,36_6.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_4.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_4.png,ave_2,40_4.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_3.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_3.png,groundtruth,45_3.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/38_6.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/38_6.png,ave_3,38_6.txt,test
Nature Aging,4_12,Which of the following options best describe the cover story?,"Inferring health trajectories
In this issue, Netta Mendelson Cohen et al. investigate individuals’ trajectories of healthy aging and age-related diseases. The researchers stitch together electronic health records with partial longitudinal coverage, using machine learning to untangle future healthy aging from chronic disease, and identify early indicators for healthy longevity. The cover image shows the study’s longevity-model features superimposed with representations of electronic health record information, which are connected via multiple solid or dotted lines that indicate differing propensities to drive the outputs of the models.
See Cohen et al.
Image: adapted from Nat. Aging  https://doi.org/10.1038/s43587-023-00536-5 (2024), Springer Nature America (background and central graph), elenabs/iStock/Getty Images Plus (remaining elements). Cover Design: Lauren Heslop",D,MAC_Bench/Nature/Cover/Nature Aging/1_2.png,MAC_Bench/Nature/Cover/Nature Aging/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,vitg,4_11.txt,MAC_Bench/Nature/Cover/Nature Aging/1_12.png,MAC_Bench/Nature/Cover/Nature Aging/1_12.png,ave_3,1_12.txt,MAC_Bench/Nature/Cover/Nature Aging/4_12.png,MAC_Bench/Nature/Cover/Nature Aging/4_12.png,groundtruth,4_12.txt,train
NATURE MEDICINE,30_9,Which of the following options best describe the cover story?,"Functional precision medicine
In this issue, Azzam and colleagues show that functional precision medicine — a combination of genomic profiling and drug-sensitivity testing of patient-derived tumor cells — can be used to provide personalized treatment recommendations for children and adolescents with relapsed or treatment-refractory cancers. The maze on the cover depicts the challenge of determining the most effective treatment option for pediatric cancers once standard-of-care therapies are no longer an option, and the brain represents functional precision medicine, which could indicate an effective path forward for doctors and their patients.
See De La Rocha et al.
Image: Oscar Negret, Florida International University. Cover design: Debbie Maizels",D,MAC_Bench/Nature/Cover/NATURE MEDICINE/24_7.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/24_7.png,vitg,24_7.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/28_5.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/28_5.png,vith,28_5.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/19_2.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_9.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_9.png,groundtruth,30_9.txt,train
NATURE METHODS,21_11,Which of the following options best describe the cover story?,"Smart lattice light-sheet microscopy
Smart lattice light-sheet microscopy captures rare cellular events. The image shows immune synapses formed between cytotoxic T lymphocytes (cyan) and tumor cells (magenta) within a population of cultured cells. Cytotoxic granules are shown in yellow.
See Shi et al.
Image: Yu Shi and Wesley Legant, University of North Carolina - Chapel Hill. Cover Design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/NATURE METHODS/21_11.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_11.png,groundtruth,21_11.txt,MAC_Bench/Nature/Cover/NATURE METHODS/18_4.png,MAC_Bench/Nature/Cover/NATURE METHODS/18_4.png,vith,18_4.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_8.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_8.png,vitg,21_8.txt,MAC_Bench/Nature/Cover/NATURE METHODS/19_10.png,MAC_Bench/Nature/Cover/NATURE METHODS/19_10.png,clip,19_10.txt,train
ACS Bio & Med Chem Au,2025_1,Which of the following options best describe the cover story?,"Mycophenolic acid (MPA), the first antibiotic from Penicillium species, inspires a researcher to explore its potential. By incorporating silicon into MPA,",C,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2023_5.png,clip,2023_5.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_5.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_5.png,vith,2024_5.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_3.png,vitg,2024_3.txt,val
Nature Reviews Neurology,20_2,Which of the following options best describe the cover story?,"Systemic support for the brain, inspired by the Review on p647.
Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/17_7.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/17_7.png,ave_2,17_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_2.png,groundtruth,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,vitg,20_6.txt,train
Nature Reviews Physics,6_4,Which of the following options best describe the cover story?,"The cover of this issue is a celebration of 100 years since Ernst Ising solved the 1D version of the Ising model. See our In Retrospect.
Image: Susanne Harris, Springer Nature Limited. Cover design: Susanne Harris.",B,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_1.png,clip,5_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_4.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_4.png,groundtruth,6_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_12.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_12.png,ave_1,3_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_8.png,vitg,1_8.txt,val
ACS Photonics,2024_12,Which of the following options best describe the cover story?,"A pump pulse is used to drive lattice vibration, and a probe pulse accompanied by a reference pulse is used to probe the vibration.",B,MAC_Bench/ACS/Cover/ACS Photonics/2016_5.png,MAC_Bench/ACS/Cover/ACS Photonics/2016_5.png,vith,2016_5.txt,MAC_Bench/ACS/Cover/ACS Photonics/2024_12.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Photonics/2015_4.png,MAC_Bench/ACS/Cover/ACS Photonics/2015_4.png,vitg,2015_4.txt,MAC_Bench/ACS/Cover/ACS Photonics/2022_4.png,MAC_Bench/ACS/Cover/ACS Photonics/2022_4.png,clip,2022_4.txt,train
ACS Applied Bio Materials,2024_2,Which of the following options best describe the cover story?,"The cover image depicts the hypothetical schematic of cubosomes (lyotropic liquid crystal nanoparticles) entering the epithelia and subsequent tissues of a lower limb (leg) with varicose veins. Although they differ in internal structure and function, cubosomes are classified as a subtype of liposomes. Our research shows that liquid crystal nanoparticles can be efficiently used for the management and therapy of varicose veins. The cover image was created using Canva as a tool. View the article.",B,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_1.png,clip,2020_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2021_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2021_1.png,vitg,2021_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_12.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_12.png,vith,2020_12.txt,val
NATURE REVIEWS GENETICS,25_10,Which of the following options best describe the cover story?,"Inspired by the Review on 165.
Cover design: Patrick Morgan.",B,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_10.png,groundtruth,25_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,clip,14_5.txt,train
Nature Ecology & Evolution,8_3,Which of the following options best describe the cover story?,"Nesting havens
Atolls are tiny specks of land scattered across the vast tropical Indo-Pacific. Because of their smallness and remoteness, these islands are often overlooked in research and conservation. This study reveals the global importance of atolls as nesting havens for about 25% of the world’s tropical seabirds, and demonstrates that the large nesting colonies power the atoll ecosystem.
See Steibl et al.
Image: James C. Russell, University of Auckland. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_3.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_3.png,groundtruth,8_3.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_6.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_6.png,clip,4_6.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_7.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_7.png,vitg,4_7.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/3_11.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/3_11.png,ave_3,3_11.txt,val
Accounts of Materials Research,2024_1,Which of the following options best describe the cover story?,Real polarized optical microscopy of a mixture of reactive thermotropic liquid crystal mesogens phase separating from a mixture of reactive monomers of a hydrogel.,B,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_3.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_3.png,vitg,2024_3.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_1.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_3.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_3.png,clip,2023_3.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_11.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_11.png,vith,2021_11.txt,train
Nature Reviews Earth & Environment,5_10,Which of the following options best describe the cover story?,"With continued anthropogenic warming, an ice-free Arctic (sea ice area <1 million km2) is inevitable. This Review outlines the various characteristics of an ice-free Arctic, highlighting that future emission trajectories will determine where, how frequently, and for how long the Arctic will be ice-free each year.
Image credit: Vicki Beaver / Alamy Stock Photo. Cover design: Carl Conway.",C,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_5.png,ave_2,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_11.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_11.png,clip,3_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_10.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_10.png,groundtruth,5_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_5.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_5.png,ave_3,3_5.txt,test
Nature Reviews Electrical Engineering,1_5,Which of the following options best describe the cover story?,"Graph neural networks (GNNs) hold potential for harnessing data power to tackle application challenges in electrical engineering, physics, material science and biology. The cover image shows the analogy between GNNs and mazes. See Li et al.
Cover design: Sam Whitham",D,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,ave_3,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,clip,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,groundtruth,1_5.txt,train
Nature Catalysis,7_10,Which of the following options best describe the cover story?,"Durable manganese oxides
In their work, Ryuhei Nakamura, Jianping Xiao, Ailong Li and colleagues report a strategy to achieve high stability of MnO2 in acidic water oxidation under relevant proton exchange membrane electrolyser conditions by tuning the oxide structure and increasing the strength of Mn–O bonds, which suppresses Mn dissolution.
See Kong et al.
Image: Tomoyuki Wakashima, RIKEN. Cover design: Alex Whitworth",C,MAC_Bench/Nature/Cover/Nature Catalysis/5_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/5_3.png,ave_0,5_3.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_8.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_8.png,clip,7_8.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_10.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_10.png,groundtruth,7_10.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_9.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_9.png,vitg,2_9.txt,train
Trends in Chemistry,6_12,Which of the following options best describe the cover story?,"Plastic upcycling is a strategy for treating plastic waste, not only to
remedy environmental pollution but also to provide tremendous resources for novel
advanced materials. In this issue, Lim and Nguyen discuss sustainable approaches
to upcycle plastics, converting them into useful chemicals and materials. The review
highlights green chemical catalysis and hybrid methods that integrate biocatalysis,
offering immense potential for valorizing waste plastics. Cover image credit: the
authors, who found joy in art design, in addition to their passion for valorizing
plastics.",C,MAC_Bench/Cell/Cover/Trends in Chemistry/6_3.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_3.png,ave_3,6_3.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_10.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_10.png,clip,6_10.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_12.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_12.png,groundtruth,6_12.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/5_11.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_11.png,vith,5_11.txt,train
Biomacromolecules,2024_4,Which of the following options best describe the cover story?,Photodynamic therapy of a tumor using NIR excitation of nanoparticles with a conjugated photosensitizer generates cell-killing reactive oxygen species. Prepared with AI assistance from Leonardo Interactive Pty Ltd.,A,MAC_Bench/ACS/Cover/Biomacromolecules/2024_4.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_9.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_9.png,vith,2021_9.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_5.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_5.png,vitg,2021_5.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2017_3.png,MAC_Bench/ACS/Cover/Biomacromolecules/2017_3.png,clip,2017_3.txt,train
Industrial & Engineering Chemistry Research,2024_10,Which of the following options best describe the cover story?,This study presents a novel,B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_19.png,vith,2022_19.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_10.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_27.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_27.png,vitg,2021_27.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_49.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_49.png,clip,2021_49.txt,train
ACS Applied Optical Materials,2024_2,Which of the following options best describe the cover story?,"Three simple Schiff bases were designed to investigate their structure–function correlations. Detailed optical studies and interesting emission switching and tuning was observed through base fume exposures, leading to discovery of a wearable fluorochromic ammonia sensor with potential for development of ammonia protective masks.",B,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_2.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_9.png,ave_1,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_9.png,vitg,2023_9.txt,train
ACS Applied Engineering Materials,2024_10,Which of the following options best describe the cover story?,"Deep eutectic solvent/surfactant functionalized titanium dioxide (TiO2) coated graphene oxide (GO) can be a sensitive, ultrafast (within 3 min), and sustainable adsorbent for the complete removal of hazardous textile dye from industrial effluent.",A,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_7.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_7.png,ave_3,2023_7.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_5.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_5.png,vith,2024_5.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_4.png,clip,2023_4.txt,train
ACS Materials Letters,2024_4,Which of the following options best describe the cover story?,"A novel synthetic strategy to epitaxially grow unconventional-phase Pt with well-defined 2H facets via B doping of a nanoseed is illustrated, enabling the study of the crystal phase dependent catalytic property of a Pt nanocatalyst.",D,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_5.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_5.png,vitg,2019_5.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2020_8.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2020_8.png,clip,2020_8.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_1.png,vith,2024_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_4.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_4.png,groundtruth,2024_4.txt,val
NATURE GENETICS,56_2,Which of the following options best describe the cover story?,"Genomic analysis of brain volumes
A genome-wide association analysis of intracranial and subcortical brain volumes identifies 254 loci and yields polygenic scores accounting for brain variation across ancestries.
See García-Marín et al.
Image: Mauricio Guzman Araiza, Altamira Studio. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/NATURE GENETICS/50_6.png,MAC_Bench/Nature/Cover/NATURE GENETICS/50_6.png,ave_2,50_6.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_2.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_2.png,groundtruth,56_2.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/55_11.png,MAC_Bench/Nature/Cover/NATURE GENETICS/55_11.png,ave_1,55_11.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/51_2.png,MAC_Bench/Nature/Cover/NATURE GENETICS/51_2.png,clip,51_2.txt,train
Nature Metabolism,6_9,Which of the following options best describe the cover story?,"Fasting proteome
Seven days of complete caloric restriction in humans leads to profound adaptations of the plasma proteome. The illustration is an artistic representation of changes in the proteome after prolonged fasting in humans.
See Pietzner et al.
Image: Saskia Beuchel. Cover Design: Thomas Phillips.",D,MAC_Bench/Nature/Cover/Nature Metabolism/6_5.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_5.png,clip,6_5.txt,MAC_Bench/Nature/Cover/Nature Metabolism/2_10.png,MAC_Bench/Nature/Cover/Nature Metabolism/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_2.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_2.png,vitg,6_2.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_9.png,groundtruth,6_9.txt,test
Science Signaling,2007_407,Which of the following options best describe the cover story?,"COVER This week's Focus Issue, published in conjunction with the Science Special Collection on Cell Signaling, features 7 new or updated pathways in the Database of Cell Signaling, which are also briefly highlighted in the associated Editorial Guide. The image depicts an ""insider's view"" of cell signaling. [Image: Christopher Bickel, AAAS]",A,MAC_Bench/Science/Cover/Science Signaling/2007_407.png,MAC_Bench/Science/Cover/Science Signaling/2007_407.png,groundtruth,2007_407.txt,MAC_Bench/Science/Cover/Science Signaling/3_136.png,MAC_Bench/Science/Cover/Science Signaling/3_136.png,ave_1,3_136.txt,MAC_Bench/Science/Cover/Science Signaling/5_233.png,MAC_Bench/Science/Cover/Science Signaling/5_233.png,clip,5_233.txt,MAC_Bench/Science/Cover/Science Signaling/2_61.png,MAC_Bench/Science/Cover/Science Signaling/2_61.png,vith,2_61.txt,train
Science Robotics,10_98,Which of the following options best describe the cover story?,"ONLINE COVER Exoskeletons—Overcoming the Ceiling Effect in Motor Skills. Learning a motor skill often plateaus, resulting in the ceiling effect whereby no further training can improve the skill level. Furuya et al. have developed a hand exoskeleton for pianists to surmount the ceiling effect in their skill level through exposure to complex finger movements that would not be possible voluntarily. They demonstrated that, after the exoskeleton was no longer used, the pianists could play faster with both their trained hand and their contralateral untrained hand with evidence of neuroplastic adaptation. This month’s cover is an image of a pianist training with the exoskeleton. Credit: Y. Ogasawara",D,MAC_Bench/Science/Cover/Science Robotics/7_64.png,MAC_Bench/Science/Cover/Science Robotics/7_64.png,vitg,7_64.txt,MAC_Bench/Science/Cover/Science Robotics/3_25.png,MAC_Bench/Science/Cover/Science Robotics/3_25.png,clip,3_25.txt,MAC_Bench/Science/Cover/Science Robotics/9_91.png,MAC_Bench/Science/Cover/Science Robotics/9_91.png,ave_2,9_91.txt,MAC_Bench/Science/Cover/Science Robotics/10_98.png,MAC_Bench/Science/Cover/Science Robotics/10_98.png,groundtruth,10_98.txt,train
NATURE MATERIALS,23_1,Which of the following options best describe the cover story?,"Sustainable aviation fuels
Lignin is an abundant source of renewable aromatic carbon and is of interest as a feedstock for sustainable fuels. This Review provides an overview of production technologies, jet fuel requirements, effects of lignin chemistry, depolymerization techniques, upgrading of bio-oils and challenges for catalysis using real biomass feedstocks.
See Webber et al.
Image and cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_1.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_1.png,groundtruth,23_1.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_2.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_2.png,vith,23_2.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/11_6.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/11_6.png,vitg,11_6.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_6.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_6.png,clip,21_6.txt,val
Cell Host&Microbe,32_10,Which of the following options best describe the cover story?,"On the cover: The cover illustrates bacteriophage modulatation of bacterial functions.
In this issue of Cell Host & Microbe, Carasso and colleagues examine metagenomic samples from IBD patients, which demonstrated that invertible
regions associate with disease severity and are modulated by bacteriophages. The bacteriophages
are more prominent during gut inflammation, and when encountering their associated
bacteria, they alter their functions by modulating inversion states, represented by
change in the bacterial color from yellow to green. Artwork by Tomm Blum.",D,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,clip,27_5.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,vitg,30_3.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,vith,31_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_10.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_10.png,groundtruth,32_10.txt,train
Biomacromolecules,2024_1,Which of the following options best describe the cover story?,"Stem cell-embedded hydrogel nanocomposites, tailored with varying stiffness, growth factors, and nanoparticles, effectively guide stem cell differentiation into chondrocytes or osteocytes, facilitating cartilage or bone regeneration.",C,MAC_Bench/ACS/Cover/Biomacromolecules/2019_9.png,MAC_Bench/ACS/Cover/Biomacromolecules/2019_9.png,vith,2019_9.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2020_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2020_10.png,clip,2020_10.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_1.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_2.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_2.png,vitg,2024_2.txt,test
Journal of Chemical Information and Modeling,2025_3,Which of the following options best describe the cover story?,"Adsorption of a molecule on a metal surface, a key initial step in surface chemical reactions: Quantum computers, faintly visible in the background, enable the modeling of strong correlation effects and complex molecule–surface interactions, surpassing the limitations of classical methods. Advanced quantum algorithms promise to revolutionize the understanding of catalytic processes, paving the way for sustainable innovations in chemistry and materials science. This image was generated using the AI platform Gemini.",B,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2016_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2016_11.png,vith,2016_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_3.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_5.png,vitg,2015_5.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_1.png,clip,2025_1.txt,train
Analytical Chemistry,2025_1,Which of the following options best describe the cover story?,"This cover illustrates a protein labeling and analysis strategy that combines a highly selective, high-affinity multicyclic peptide with a bright fluorescent probe for the specific and sensitive detection and visualization of protein expression on human T cells.",A,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_31.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_31.png,vith,2022_31.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2024_34.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2024_34.png,vitg,2024_34.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,clip,2022_33.txt,train
NATURE REVIEWS IMMUNOLOGY,24_3,Which of the following options best describe the cover story?,"Flu vaccines, inspired by the Review on p736.
Cover design: Simon Bradbrook",B,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/21_11.png,vith,21_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_3.png,groundtruth,24_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,vitg,18_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,clip,13_4.txt,val
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_1,Which of the following options best describe the cover story?,"Future of the gut microbiome, inspired by the Viewpoint on p830
Cover design: Laura Marshall",B,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_6.png,ave_2,20_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_1.png,groundtruth,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,clip,20_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,ave_1,21_2.txt,val
Cell Reports,43_9,Which of the following options best describe the cover story?,"On the cover: A red sea urchin can attain a lifespan of more than 100 years without
showing signs of aging. In this issue, Polinski et al. report a genome assembly for the long-lived red sea urchin and find chromosome rearrangements
and expansion of gene families associated with long-term maintenance of tissue homeostasis,
disease resistance, longevity, and negligible aging that are distinct from short-lived
sea urchin species. Concept and artwork: Andrea G. Bodnar and Jennifer M. Polinski.",C,MAC_Bench/Cell/Cover/Cell Reports/4_3.png,MAC_Bench/Cell/Cover/Cell Reports/4_3.png,vitg,4_3.txt,MAC_Bench/Cell/Cover/Cell Reports/21_4.png,MAC_Bench/Cell/Cover/Cell Reports/21_4.png,clip,21_4.txt,MAC_Bench/Cell/Cover/Cell Reports/43_9.png,MAC_Bench/Cell/Cover/Cell Reports/43_9.png,groundtruth,43_9.txt,MAC_Bench/Cell/Cover/Cell Reports/2_5.png,MAC_Bench/Cell/Cover/Cell Reports/2_5.png,vith,2_5.txt,train
Accounts of Chemical Research,2024_7,Which of the following options best describe the cover story?,The use of traditional chemical tools together with the molecules and machinery of the cell have opened a new frontier in our ability to synthesize complex molecules and molecular systems with new properties.,C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_3.png,clip,2020_3.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_12.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_12.png,vitg,2014_12.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_7.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2013_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2013_4.png,vith,2013_4.txt,val
Trends in Genetics,40_12,Which of the following options best describe the cover story?,"With distinct surface and cave ecotypes, the fish Astyanax mexicanus is a powerful model to study the genetic basis of adaptation to new environments.
In this issue, Nicolas Rohner and colleagues summarize recent advances in A. mexicanus genetics and discuss how this model is yielding broader insights into the genetic
basis of adaptation and evolution. Image credit: Jennifer Idol/Stocktrek Images (Getty
Images).",B,MAC_Bench/Cell/Cover/Trends in Genetics/32_4.png,MAC_Bench/Cell/Cover/Trends in Genetics/32_4.png,clip,32_4.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_12.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_12.png,groundtruth,40_12.txt,MAC_Bench/Cell/Cover/Trends in Genetics/37_6.png,MAC_Bench/Cell/Cover/Trends in Genetics/37_6.png,ave_1,37_6.txt,MAC_Bench/Cell/Cover/Trends in Genetics/30_12.png,MAC_Bench/Cell/Cover/Trends in Genetics/30_12.png,vitg,30_12.txt,train
Cell Reports Physical Science,5_9,Which of the following options best describe the cover story?,"On the cover: Manufacturing fine three-dimensional structures from mesoscale down
to nanoscale is of considerable importance in multiple application backgrounds. Jiang et al. find that the top plateau of a freezing “triangle” nanofluid drop can transit from
an initial triangle, through a hexagon and a counter triangle, to a final hexagon
with increasing drop height. By choosing proper 2D patterns, their study allows versatile
out-of-plane shape control. The cover graphic was designed by Peng Yu.",C,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_3.png,vith,1_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,vitg,2_9.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_9.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_9.png,groundtruth,5_9.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_4.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_4.png,clip,4_4.txt,val
ACS Chemical Biology,2024_8,Which of the following options best describe the cover story?,"screening of 41716 compounds in the nematode Caenorhabditis elegans identifies pre-clinical anticancer mycotoxins chaetocin and chetomin as potent inducers of novel nuclear metal homeostasis protein NUMR-1/2 in the alimentary canal.  Chaetomiaceae fungi and C. elegans inhabit similar environments, raising the possibility that NUMR-1/2 functions as a resistance mechanism.",A,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_8.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2018_4.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2018_4.png,clip,2018_4.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_2.png,vitg,2025_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2018_12.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2018_12.png,ave_2,2018_12.txt,test
Nature Cell Biology,26_9,Which of the following options best describe the cover story?,"Hydrostatic pressure in development
Hydrostatic pressure regulates embryonic competence in the developing neural crest.
See Alasaadi et al.
Image: Julien Marcetteau. Cover design: Lauren Heslop",D,MAC_Bench/Nature/Cover/Nature Cell Biology/15_11.png,MAC_Bench/Nature/Cover/Nature Cell Biology/15_11.png,vitg,15_11.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/14_8.png,MAC_Bench/Nature/Cover/Nature Cell Biology/14_8.png,ave_1,14_8.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/10_9.png,MAC_Bench/Nature/Cover/Nature Cell Biology/10_9.png,clip,10_9.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_9.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_9.png,groundtruth,26_9.txt,val
Nature Cell Biology,26_4,Which of the following options best describe the cover story?,"Focus on cell death
The cover shows 3-colour live imaging in vivo demonstrating a role for ferroptosis-like cell death in triggering macrophage recruitment but delaying the resolution of inflammation during wounding in Drosophila. See Focus for more content. Focus
See Davidson et al.
Image: Andrew J. Davidson, University of Glasgow. Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Cell Biology/12_4.png,MAC_Bench/Nature/Cover/Nature Cell Biology/12_4.png,clip,12_4.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/19_4.png,MAC_Bench/Nature/Cover/Nature Cell Biology/19_4.png,vitg,19_4.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_4.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_4.png,groundtruth,26_4.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/19_12.png,MAC_Bench/Nature/Cover/Nature Cell Biology/19_12.png,vith,19_12.txt,train
ACS Applied Bio Materials,2025_2,Which of the following options best describe the cover story?,This cover art describes an antibacterial hydrogel material covering wounds on the skin. The hydrogel hosts extracellular vesicles derived from mint leaves. These extracellular vesicles kill the bacteria in the wound site and promote wound healing. The cover art is made with Adobe Firefly.,B,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_2.png,ave_3,2024_2.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2018_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2018_1.png,clip,2018_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_12.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_12.png,vith,2019_12.txt,train
Nature Reviews Neurology,20_9,Which of the following options best describe the cover story?,"Diversity, equity and inclusion in reaching global brain health, inspired by the Editorial on p199.
Cover design: Philip Patenall",A,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_9.png,groundtruth,20_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_12.png,vith,20_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_10.png,vitg,19_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_8.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_8.png,clip,18_8.txt,train
ACS Chemical Biology,2024_9,Which of the following options best describe the cover story?,"Cancer cells showed an incredible adaptive tumor response to the inhibition of the sequentially mutated EGFR, triggering the need of designing novel mutant-selective TKIs.",C,MAC_Bench/ACS/Cover/ACS Chemical Biology/2016_6.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2016_6.png,vith,2016_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2017_5.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2017_5.png,clip,2017_5.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_3.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_3.png,vitg,2024_3.txt,train
Chemical & Biomedical ImagingOpen Access,2025_1,Which of the following options best describe the cover story?,"This cover art represents the development of hyperspectral 3D stimulated Raman scattering microscopy (hyper-3D SRS) for studying lipid droplet (LD) dynamics during early embryogenesis. The illustration also highlights the spatial and chemical diversity of LDs within individual embryonic cells, revealing dynamic relationships between LD size and unsaturation levels as embryos develop. Sub-micrometer resolution and 3D optical sectioning capabilities of the hyper-3D SRS method uncover metabolic heterogeneity, showing its potential for clinical applications in the future.",A,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_2.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_3.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_3.png,ave_2,2023_3.txt,train
NATURE IMMUNOLOGY,25_2,Which of the following options best describe the cover story?,"Therapeutic single-cell atlas in inflammatory bowel disease
Buckley and colleagues profile individuals with Crohn’s disease and ulcerative colitis before and after adalimumab therapy. Specific pre-treatment differences in the epithelial and myeloid compartments were associated with remission outcomes in both diseases. The authors also describe the cellular circuitry in patients from the non-remission group after treatment.
See Thomas et al.
Image: Calliope Dendrou, University of Oxford. Cover design: Emily Paul",A,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_2.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_2.png,groundtruth,25_2.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/7_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/7_5.png,vith,7_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/16_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/16_5.png,vitg,16_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/19_6.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/19_6.png,clip,19_6.txt,val
Nature Reviews Materials,10_1,Which of the following options best describe the cover story?,"Tissue biomechanics provides essential biological information that is important for various biomedical applications, and conformable electronic devices are instrumental for decoding this information. The cover shows an artist’s impression of island-bridge structures, consisting of rigid functional ""islands"" connected by flexible ""bridges"", which allow devices to be stretched or bent without losing functionality. See Yoon H. et al.
Cover: David Johnston",A,MAC_Bench/Nature/Cover/Nature Reviews Materials/10_1.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/10_1.png,groundtruth,10_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,vitg,9_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_7.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_7.png,vith,2_7.txt,train
BDJ In Practice,37_10,Which of the following options best describe the cover story?,"Volume 37 | Issue 3 | March
When PHE was abolished, Dental Public Health found itself in a tricky position. This month's cover feature asks where the Parvus sed potens specialty is today",A,MAC_Bench/Nature/Cover/BDJ In Practice/37_10.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_10.png,groundtruth,37_10.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_9.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_9.png,vitg,35_9.txt,MAC_Bench/Nature/Cover/BDJ In Practice/33_12.png,MAC_Bench/Nature/Cover/BDJ In Practice/33_12.png,ave_3,33_12.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,clip,36_1.txt,train
The Journal of Physical Chemistry C,2025_7,Which of the following options best describe the cover story?,"Collage of artwork from recent issues of J. Phys. Chem. C. Background: Light-Induced Increase of the Local Molecular Coverage on a Surface (J. Phys. Chem. C 2024, 128 (14), 5919–5926. DOI:",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2024_4.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2024_4.png,vitg,2024_4.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_7.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2018_38.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2018_38.png,clip,2018_38.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2022_29.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2022_29.png,vith,2022_29.txt,val
ACS Catalysis,2024_15,Which of the following options best describe the cover story?,"The cover art illustrates a convenient and efficient strategy for selective arylation at the C4 site of 2-pyridones by palladium and norbornene competitive catalysis, which provides efficient synthesis of functional 4-aryl-2-pyridone scaffolds as valuable building blocks in medicinal chemistry.",A,MAC_Bench/ACS/Cover/ACS Catalysis/2024_15.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_15.png,groundtruth,2024_15.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2011_10.png,MAC_Bench/ACS/Cover/ACS Catalysis/2011_10.png,vitg,2011_10.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2015_1.png,MAC_Bench/ACS/Cover/ACS Catalysis/2015_1.png,ave_0,2015_1.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2018_4.png,MAC_Bench/ACS/Cover/ACS Catalysis/2018_4.png,clip,2018_4.txt,test
ACS Physical Chemistry Au,2024_3,Which of the following options best describe the cover story?,"Protein engineering is in large part “a game” to construct a protein from amino acid building blocks. The game can be stochastic, such as directed evolution or, if the rules of the game are known, rational design can be involved. Here, we took advantage of both approaches to develop new archaerhodopsin-3-based fluorescent genetically encoded voltage indicators (GEVIs) with red-shifted absorption bands and potential-dependent bright fluorescence.",B,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2025_1.png,vith,2025_1.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2023_6.png,vitg,2023_6.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_2.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_2.png,clip,2022_2.txt,train
ACS Applied Engineering Materials,2024_12,Which of the following options best describe the cover story?,"Sulfate-free surface cellulose nanocrystals helped to fabricate highly stable, sensitive, and lightweight flexible thermal sensors for continuous monitoring of temperature profiles. Along with high stability, a sensitivity of 0.6%/℃ can be achieved with the CNC-based sensors.",D,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_7.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_7.png,vith,2023_7.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,vitg,2024_8.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,groundtruth,2024_12.txt,val
Chemical Research in Toxicology,2024_4,Which of the following options best describe the cover story?,"Tobacco-specific nitrosamine, NNK, and its main in vivo metabolite, NNAL, are potent human lung carcinogens, and their enhanced clearance through glucuronidation will reduce the human lung cancer risk. Kava was demonstrated to enhance both O- and N-glucuronidation of NNAL among pilot trial participants, with N-glucuronidation predictive from UGT2B10 SNPs.",B,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_1.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_1.png,clip,2017_1.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_4.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,ave_1,2023_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_9.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_9.png,vith,2023_9.txt,train
One Earth,7_8,Which of the following options best describe the cover story?,"On the cover: The chemical sector is a vital pillar of modern society, providing goods
and services that meet the everyday needs of the individual and offer solutions to
society-wide challenges: healthcare, agriculture, manufacturing, energy, and water
treatment, to name a few. Yet there are also trade-offs and externalities: emissions,
pollutants, and wastes are synonymous with today's chemical operations. A responsible
and sustainable future will only be realized if the chemical sector embraces circularity.
Hal Bergman for Getty Images.",B,MAC_Bench/Cell/Cover/One Earth/6_2.png,MAC_Bench/Cell/Cover/One Earth/6_2.png,vitg,6_2.txt,MAC_Bench/Cell/Cover/One Earth/7_8.png,MAC_Bench/Cell/Cover/One Earth/7_8.png,groundtruth,7_8.txt,MAC_Bench/Cell/Cover/One Earth/4_10.png,MAC_Bench/Cell/Cover/One Earth/4_10.png,clip,4_10.txt,MAC_Bench/Cell/Cover/One Earth/4_3.png,MAC_Bench/Cell/Cover/One Earth/4_3.png,vith,4_3.txt,train
NATURE BIOTECHNOLOGY,42_1,Which of the following options best describe the cover story?,"Recording neural activity in organoids
An artistic representation of KiriE, a platform inspired by the Japanese art of kirigami. Yang et al. have developed KiriE, a platform with a flexible design that preserves neural organoid morphology and enables integration with optogenetic and pharmacological manipulation over many months.
See Yang et al.
Image: Mesa Schumacher. Cover design: Erin Dewalt",D,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/34_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/34_4.png,clip,34_4.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_6.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_6.png,vith,39_6.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_12.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_12.png,vitg,42_12.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_1.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_1.png,groundtruth,42_1.txt,train
ACS Applied Polymer Materials,2024_20,Which of the following options best describe the cover story?,The combination of a strong electronegative effect and the hydrophobic feature of –CF3 as well as the increase of free volume contributes to the improved energy capability of the FPI film.,A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_20.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_20.png,groundtruth,2024_20.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_11.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_11.png,ave_0,2024_11.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_1.png,vitg,2024_1.txt,val
Journal of the American Chemical Society,2024_38,Which of the following options best describe the cover story?,"Metal atom encapsulated silicon cage superatoms (M@Si16) optimize electronic properties by satisfying both electronic shell closure and geometric filling. Group 6 metal encapsulation exceeds the 68-electron closed shell by 2 electrons. When deposited on a C60 substrate, these nanoclusters achieve +2 valency,",B,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2022_31.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2022_31.png,vith,2022_31.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_38.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_38.png,groundtruth,2024_38.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_5.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_5.png,clip,2016_5.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_42.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_42.png,vitg,2016_42.txt,val
Cell Host&Microbe,32_11,Which of the following options best describe the cover story?,"On the cover: Microbial metabolites mediate host-microbiome communication. Determining
how host-microbial interactions contribute to inflammatory pathologies requires efforts
to connect disease-associated gut microbes (pink) to alterations in gut and plasma
metabolites (blue). In this issue of Cell Host & Microbe, Schirmer and Stražar et al. establish microbe-metabolite connections across disease severity in the PROTECT cohort
of pediatric ulcerative colitis patients. Paired metagenomics and untargeted metabolomics
revealed disease-associated microbes, microbial genes, and metabolites. The authors
show how subsequent culturomics profiling can be used to connect specific microbial
species with metabolite changes in disease.",C,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,vith,31_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/22_1.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/22_1.png,clip,22_1.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_11.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_11.png,groundtruth,32_11.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,vitg,30_3.txt,train
Immunity,57_5,Which of the following options best describe the cover story?,"On the cover: Memory B cells (MBCs) underlie long-lived humoral immunity and are key
to the efficacy of prime-boost vaccines. In this issue, Wang et al. report that MBCs differ in their recall ability and that expression of the transcription
regulator ZFP318, which regulates expression of mitochondrial genes, defines MBCs
with high recall ability. The role of ZFP318 in preventing mitochondrial wear-and-tear
and reactivation-induced cell death is illustrated in the form of a fueling station,
providing sustenance to a car on a long journey. Cover image by: Xiaonan Wang.",C,MAC_Bench/Cell/Cover/Immunity/33_2.png,MAC_Bench/Cell/Cover/Immunity/33_2.png,vith,33_2.txt,MAC_Bench/Cell/Cover/Immunity/38_4.png,MAC_Bench/Cell/Cover/Immunity/38_4.png,clip,38_4.txt,MAC_Bench/Cell/Cover/Immunity/57_5.png,MAC_Bench/Cell/Cover/Immunity/57_5.png,groundtruth,57_5.txt,MAC_Bench/Cell/Cover/Immunity/46_2.png,MAC_Bench/Cell/Cover/Immunity/46_2.png,vitg,46_2.txt,train
Science Signaling,2007_413,Which of the following options best describe the cover story?,"COVER This week features a  Perspective on the effects of adenylyl cyclase 5 signaling on cardiac hypertrophy and other disorders associated with aging. [Image: David M. Allen, Purdue University]",D,MAC_Bench/Science/Cover/Science Signaling/3_116.png,MAC_Bench/Science/Cover/Science Signaling/3_116.png,vith,3_116.txt,MAC_Bench/Science/Cover/Science Signaling/9_420.png,MAC_Bench/Science/Cover/Science Signaling/9_420.png,clip,9_420.txt,MAC_Bench/Science/Cover/Science Signaling/2_68.png,MAC_Bench/Science/Cover/Science Signaling/2_68.png,vitg,2_68.txt,MAC_Bench/Science/Cover/Science Signaling/2007_413.png,MAC_Bench/Science/Cover/Science Signaling/2007_413.png,groundtruth,2007_413.txt,train
ACS Photonics,2024_4,Which of the following options best describe the cover story?,"The theoretical efficiency limit of a solar cell increases with the mean curvature of the device, due to a higher ratio of emission area to volume and thus a lower non-radiative voltage loss. Image obtained using ChatGPT.",A,MAC_Bench/ACS/Cover/ACS Photonics/2024_4.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Photonics/2022_4.png,MAC_Bench/ACS/Cover/ACS Photonics/2022_4.png,ave_1,2022_4.txt,MAC_Bench/ACS/Cover/ACS Photonics/2015_10.png,MAC_Bench/ACS/Cover/ACS Photonics/2015_10.png,clip,2015_10.txt,MAC_Bench/ACS/Cover/ACS Photonics/2019_11.png,MAC_Bench/ACS/Cover/ACS Photonics/2019_11.png,vith,2019_11.txt,train
Nature Geoscience,17_5,Which of the following options best describe the cover story?,"Mapping Antarctica’s vegetation
Satellite-based mapping of vegetation shows that photosynthetic life occupies a total area of 44.2 km2 across Antarctica. This drone image reveals a striking landscape mosaic of mosses, lichens, and cyanobacteria covering ice-free areas of Robert Island, Antarctica — one of the most densely vegetated regions identified in the continent-wide mapping effort.
See Walshaw et al.
Image: Andrew Gray, Norsk institutt for naturforskning. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/11_5.png,MAC_Bench/Nature/Cover/Nature Geoscience/11_5.png,vith,11_5.txt,MAC_Bench/Nature/Cover/Nature Geoscience/5_6.png,MAC_Bench/Nature/Cover/Nature Geoscience/5_6.png,clip,5_6.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_5.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_5.png,groundtruth,17_5.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_2.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_2.png,vitg,17_2.txt,val
Trends in Cognitive Sciences,28_2,Which of the following options best describe the cover story?,"Is working memory (WM) domain-general or domain-specific? In this
issue of Trends in Cognitive Sciences, Nazbanou Nozari and Randi C. Martin explore the
domain-generality and domain-specificity of WM across three levels: computations,
neural
substrates, and applications. They propose a nuanced taxonomy, revealing the varying
degrees of domain-generality and domain-specificity across these levels, with practical
implications for WM training. The tiles on the cover visually represent the three
levels
explored by the authors. Cover image by Marissa Sirois.",C,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/21_6.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/21_6.png,vitg,21_6.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/23_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/23_1.png,clip,23_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_2.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_2.png,groundtruth,28_2.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/22_3.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/22_3.png,vith,22_3.txt,val
Nature Sustainability,7_9,Which of the following options best describe the cover story?,"Closing the loop of urea production
Urea is an essential nitrogenous fertilizer in modern agriculture. Its production, however, is too carbon and energy intensive. Here Chuanxin He and colleagues green this process through pulsed co-electrolysis of CO2 and nitrate.
See Qi Hu et al.
Image: Hangzhou Sphere Studio. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/Nature Sustainability/7_9.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_9.png,groundtruth,7_9.txt,MAC_Bench/Nature/Cover/Nature Sustainability/4_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/4_4.png,vith,4_4.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_4.png,clip,7_4.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_5.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_5.png,vitg,7_5.txt,train
Environment & Health,2025_2,Which of the following options best describe the cover story?,The use of ibuprofen could mitigate the association of long-term exposure to PM2.5 and its components with all-cause and cause-specific mortality.,C,MAC_Bench/ACS/Cover/Environment & Health/2023_2.png,MAC_Bench/ACS/Cover/Environment & Health/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Environment & Health/2025_2.png,MAC_Bench/ACS/Cover/Environment & Health/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_5.png,MAC_Bench/ACS/Cover/Environment & Health/2024_5.png,ave_1,2024_5.txt,train
Nature Food,5_3,Which of the following options best describe the cover story?,"Rice resistance to insects
Intensive crop production systems are highly susceptible to pests. The brown planthopper (BPH, Nilaparvata lugens) poses a major threat to rice cultivation, damaging plants by feeding on phloem sap, depositing eggs and transmitting viruses. Although rice plants respond to BPH infestations through a complex signalling network, the insect has developed strategies to bypass this natural defence, including the activation of susceptibility genes. One such gene, OsLRR2, encodes a leucine-rich repeat protein that facilitates BPH infestation further, compromising yields. Recent field trials show that knocking out OsLRR2 can substantially reduce BPH infestation and enhance biological control by attracting natural enemies. This mechanism can be leveraged to develop high-yielding, pest-resistant rice varieties through advanced breeding techniques.
See Kuai et al.
Image: Nigel Cattlin / Alamy Stock Photo. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/Nature Food/4_3.png,MAC_Bench/Nature/Cover/Nature Food/4_3.png,clip,4_3.txt,MAC_Bench/Nature/Cover/Nature Food/5_3.png,MAC_Bench/Nature/Cover/Nature Food/5_3.png,groundtruth,5_3.txt,MAC_Bench/Nature/Cover/Nature Food/3_12.png,MAC_Bench/Nature/Cover/Nature Food/3_12.png,vitg,3_12.txt,MAC_Bench/Nature/Cover/Nature Food/4_10.png,MAC_Bench/Nature/Cover/Nature Food/4_10.png,ave_3,4_10.txt,val
Trends in Ecology & Evolution,39_9,Which of the following options best describe the cover story?,"Repeated adaptation occurs when different lineages respond to similar
environmental challenges. If the same genes are involved, the genetic basis of adaptation
might be predictable. On pages 396–407, Magdalena Bohutínská and Catherine Peichel
propose that divergence time among lineages is a key factor driving variability in
gene
reuse during repeated adaptation. They discuss the underlying causes and show that
more recently diverged lineages exhibit higher gene reuse but the relationship becomes
less clear at older divergence time scales. The cover image shows three mostly lowland
lineages of Arabidopsis arenosa (bottom row), which have repeatedly adapted to the
alpine environment (top row). Photos courtesy of Doubravka Požárová.",B,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_1.png,ave_3,34_1.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_9.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_9.png,groundtruth,39_9.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_4.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_4.png,ave_2,36_4.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/35_3.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/35_3.png,clip,35_3.txt,train
Science Immunology,9_97,Which of the following options best describe the cover story?,"ONLINE COVER The Immunology of Human Schistosomiasis. Schistosomiasis is a parasitic disease caused by blood flukes in the genus Schistosoma. Humans are typically infected through agricultural, domestic, and fishing activities that expose them to contaminated water. Houlder et al. studied how the immune features of schistosomiasis change over time by tracking immune responses during acute human Schistosoma mansoni infections in a controlled experimental setting. The early stages of infection were dominated by an inflammatory type 1 T helper (TH1) cell–skewed response regardless of whether participants were infected with male or female cercariae-stage parasites. By 8 weeks, however, type 2 T helper (TH2) and T regulatory (Treg) cells dominated the response, consistent with chronic schistosomiasis. This month’s cover features fishermen on Lake Malawi near Cape Maclear, Malawi, a site endemic for schistosomiasis. Credit: Robert Harding Picture Libr. Ltd/Getty Images",B,MAC_Bench/Science/Cover/Science Immunology/8_83.png,MAC_Bench/Science/Cover/Science Immunology/8_83.png,vitg,8_83.txt,MAC_Bench/Science/Cover/Science Immunology/9_97.png,MAC_Bench/Science/Cover/Science Immunology/9_97.png,groundtruth,9_97.txt,MAC_Bench/Science/Cover/Science Immunology/3_20.png,MAC_Bench/Science/Cover/Science Immunology/3_20.png,vith,3_20.txt,MAC_Bench/Science/Cover/Science Immunology/3_28.png,MAC_Bench/Science/Cover/Science Immunology/3_28.png,clip,3_28.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_3,Which of the following options best describe the cover story?,"Food insecurity, inspired by the Review on p668.
Cover design: Laura Marshall",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_10.png,vith,18_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_12.png,clip,20_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_8.png,vitg,21_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_3.png,groundtruth,21_3.txt,train
Nature Nanotechnology,19_10,Which of the following options best describe the cover story?,"A DNA turbine across a nanopore
The cover image depicts the design of a DNA origami-based nanoturbine with a central axle connected to three blades arranged in a chiral configuration docked into a solid-state nanopore. Imaged by a single-molecule technique, the nanoturbine shows sustained rotation driven by a transmembrane electrochemical potential across the nanopore.
See Shi et al.
Image: Cees Dekker Lab / SciXel. Cover design: Valentina Monaco",B,MAC_Bench/Nature/Cover/Nature Nanotechnology/4_5.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/4_5.png,ave_2,4_5.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_10.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_10.png,groundtruth,19_10.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/14_4.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/14_4.png,clip,14_4.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_4.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_4.png,vith,18_4.txt,train
Trends in Biotechnology,42_5,Which of the following options best describe the cover story?,"Systems and synthetic biology control 'knobs' can design and reprogram
bacterial phenotypes, illustrated as light bulbs. However, inherent genomic redundancies
and the presence of unknown factors make genome manipulation difficult and undermine
the performance of desired functionalities. In pages 1048–1063 of this issue, Kim
and
colleagues discuss integrative top-down and bottom-up genome reduction schemes.
These schemes make it possible to design 'optimal genomes' that are more amenable
to genetic reprogramming and can execute targeted functions in a more effective and
orthogonal fashion. Cover image from Kangsan Kim, Donghui Choe, and Byung-Kwan Cho.",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_5.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_5.png,groundtruth,42_5.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_8.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_8.png,clip,38_8.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/32_11.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/32_11.png,vith,32_11.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,vitg,38_12.txt,val
Nature Cities,2_1,Which of the following options best describe the cover story?,"Not just blowing in the wind
Plants find interesting places in cities, with some planted and some establishing on their own. A study by Kun Song and colleagues considers seed-dispersal modes of this latter group in cities in Yunnan Province, China, and finds that dispersal by self-propulsion and dispersal by animals are more common than by wind, and all are much more common than by water.
See Song et al.
Image: Zhiwen Gao, East China Normal University. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,vith,1_11.txt,MAC_Bench/Nature/Cover/Nature Cities/2_1.png,MAC_Bench/Nature/Cover/Nature Cities/2_1.png,groundtruth,2_1.txt,MAC_Bench/Nature/Cover/Nature Cities/1_6.png,MAC_Bench/Nature/Cover/Nature Cities/1_6.png,clip,1_6.txt,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,vitg,1_2.txt,train
Nature Reviews Bioengineering,2_4,Which of the following options best describe the cover story?,"Human brain organoids can partly mimic the structure and function of the human brain and are being explored for the investigation of human brain development, biology and disease. With their increasing complexity and applications, ethical questions have arisen focused on how to classify, use and regulate these tissues. See Nathan A. Shlobin et al
Cover image: Simon Bradbrook",A,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_4.png,groundtruth,2_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,vitg,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_3.png,ave_2,1_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_5.png,clip,1_5.txt,val
Trends in Cell Biology,34_12,Which of the following options best describe the cover story?,"Microtubules organize various cellular processes through their dynamic
ends, as well as their stable shafts. Plenty of microtubule-binding proteins involved
in
these processes were recently shown to undergo liquid-liquid phase separation (LLPS)
and form liquid- or gel-like condensates (shown here as gooey material wrapping the
microtubules). However, it is unclear whether LLPS is necessary for the functions
of the
proteins involved, or is it a by-product related to protein concentration. On pages
18–30
in this issue, Vladimir Volkov and Anna Akhmanova discuss the evidence in favor and
against the occurrence of LLPS and its functional significance for microtubule-based
processes in cells. Cover design by Nemo Andrea (distributed under CC-BY-4.0).",D,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_12.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_12.png,clip,27_12.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_11.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_11.png,vitg,29_11.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/20_3.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/20_3.png,vith,20_3.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_12.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_12.png,groundtruth,34_12.txt,test
Macromolecules,2024_10,Which of the following options best describe the cover story?,"Upon specific stimuli, breaking and reforming of the chemical bonds in associative covalent adaptable networks (CANs) allow the rearrangement of network topology, offering the potential to address the challenge of recycling thermosets. A kinetic Monte Carlo model involving both cross-linking and exchange reactions is constructed to provide an in-depth understanding of the reaction kinetics for the synthesis of CANs. View the article.",B,MAC_Bench/ACS/Cover/Macromolecules/2012_12.png,MAC_Bench/ACS/Cover/Macromolecules/2012_12.png,ave_2,2012_12.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_10.png,MAC_Bench/ACS/Cover/Macromolecules/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_19.png,MAC_Bench/ACS/Cover/Macromolecules/2010_19.png,clip,2010_19.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_12.png,MAC_Bench/ACS/Cover/Macromolecules/2024_12.png,ave_1,2024_12.txt,train
Matter,7_2,Which of the following options best describe the cover story?,"On the cover: This cover features luminous 3D networks and swirling color trails against
a matrix of elliptical forms, symbolizing the innovative exploration of materials'
properties through computational modeling. In this issue, Prof. Simon Billinge from Columbia University explore the concept of a genome as applied to materials. The image symbolizes how
different ways of thinking about genomic codings of material structure can lead to
new insights in materials discovery. Image courtesy of the author.",B,MAC_Bench/Cell/Cover/Matter/6_3.png,MAC_Bench/Cell/Cover/Matter/6_3.png,clip,6_3.txt,MAC_Bench/Cell/Cover/Matter/7_2.png,MAC_Bench/Cell/Cover/Matter/7_2.png,groundtruth,7_2.txt,MAC_Bench/Cell/Cover/Matter/2_5.png,MAC_Bench/Cell/Cover/Matter/2_5.png,vitg,2_5.txt,MAC_Bench/Cell/Cover/Matter/2_1.png,MAC_Bench/Cell/Cover/Matter/2_1.png,ave_1,2_1.txt,test
ACS Applied Optical Materials,2024_12,Which of the following options best describe the cover story?,A fiber-based optical thermometry using silicon-vacancy color centers in microdiamonds is reported.,C,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,ave_2,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,clip,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_4.png,vith,2023_4.txt,val
Nature Photonics,18_1,Which of the following options best describe the cover story?,"Femtosecond fieldoscopy
An artistic impression of ‘femtosecond fieldoscopy’, whereby a femtosecond near-infrared light pulse interacts with an ethanol molecule in the liquid phase. A signature of the interaction is imparted on the pulse’s light field, allowing one to retrieve valuable information about the molecular excitation dynamics.
See Srivastava et al.
Image: Soledad Cook-Ordonez, Freelance scientific visual communicator. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Photonics/5_7.png,MAC_Bench/Nature/Cover/Nature Photonics/5_7.png,clip,5_7.txt,MAC_Bench/Nature/Cover/Nature Photonics/14_7.png,MAC_Bench/Nature/Cover/Nature Photonics/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_1.png,MAC_Bench/Nature/Cover/Nature Photonics/18_1.png,groundtruth,18_1.txt,MAC_Bench/Nature/Cover/Nature Photonics/17_2.png,MAC_Bench/Nature/Cover/Nature Photonics/17_2.png,vitg,17_2.txt,val
Med,5_8,Which of the following options best describe the cover story?,"On the cover: Traditional risk factors used to estimate the risk of developing coronary
artery disease (CAD) may still miss some individuals. CAD has a strong genetic component,
and a combination of genetic and clinical factors can yield a CAD polygenic risk score
(CAD PRS). In this issue of Med, Truong et al. develop a genome-wide CAD PRS and then explore its impact on the relationship between
clinical risk factors and CAD. In individuals with a high CAD PRS, the effect of some
known risk factors, such as type 2 diabetes, is mitigated, whereas it is enhanced
for other risk factors, such as elevated cholesterol levels. These findings underscore
the complex interplay between genetics and lifestyle factors in CAD risk, highlighting
the need for personalized prevention strategies. Cover credit: Westend61/Westend61
via Getty Images.",D,MAC_Bench/Cell/Cover/Med/4_1.png,MAC_Bench/Cell/Cover/Med/4_1.png,vitg,4_1.txt,MAC_Bench/Cell/Cover/Med/5_12.png,MAC_Bench/Cell/Cover/Med/5_12.png,clip,5_12.txt,MAC_Bench/Cell/Cover/Med/2_2.png,MAC_Bench/Cell/Cover/Med/2_2.png,ave_1,2_2.txt,MAC_Bench/Cell/Cover/Med/5_8.png,MAC_Bench/Cell/Cover/Med/5_8.png,groundtruth,5_8.txt,train
Nature Reviews Chemistry,8_10,Which of the following options best describe the cover story?,"The interface between an electrode and electrolyte is crucial for electrochemical devices. Charged and neutral species interact in this region, which can lead to compositional and structural changes of the electrode, in turn altering the interface itself. Further to this, an electrochemical system’s reaction efficiency and selectivity, and overall physical stability can degrade over time. Understanding how electrochemical interfaces behave before, during, and after operation is therefore critical. This Review discusses a range of complementary techniques to study this interface as shown on the cover where incident irradiation of different wavelengths interrogate a golden surface. See Pastor et al.
Image: Ernest Pastor & F. Pelayo García de Arquer. Cover design: Carl Conway",D,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/4_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/4_2.png,vitg,4_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,ave_2,7_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_7.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_7.png,clip,8_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_10.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_10.png,groundtruth,8_10.txt,val
NATURE ENERGY,9_7,Which of the following options best describe the cover story?,"Solar-powered drones
Demonstration of high performance, upscaling and product integration for perovskite photovoltaics is key to advancing the technology. Through engineering of the photoactive layer and substrate, Hailegnaw et al. show lightweight perovskite solar cells with improved specific power and operational stability, as well as integration into a drone for self-powered flights.
See Hailegnaw et al. and Research Briefing
Image: Stepan Demchyshyn and Christoph Putz, SoMaP, JKU Linz. Cover design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/NATURE ENERGY/9_7.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_7.png,groundtruth,9_7.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/7_6.png,MAC_Bench/Nature/Cover/NATURE ENERGY/7_6.png,clip,7_6.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_6.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_6.png,vith,9_6.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_11.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_11.png,ave_2,9_11.txt,train
Nature Water,2_2,Which of the following options best describe the cover story?,"Sanitation in dense urban areas
A simple extension of conventional sanitation technologies cannot meet the rising needs in the rapidly expanding cities of the global south. The Comment by Abishek Sankara Narayan and colleagues presents a portfolio approach that systematically considers the co-existence of various sanitation systems, including centralized and decentralized sewer-based systems, varied types of on-site blackwater and greywater treatment, and household-level treatment in situ. The approach optimizes the integration of these systems to achieve multiple outcomes, including public health, environmental protection, climate resilience, resource recovery, and equity. The cover image provides an aerial view of a densely populated township in South Africa.
See Narayan et al.
Image: John Wang / Photodisc / Getty. Cover design: Laoise Mac Gabhann",B,MAC_Bench/Nature/Cover/Nature Water/1_9.png,MAC_Bench/Nature/Cover/Nature Water/1_9.png,vitg,1_9.txt,MAC_Bench/Nature/Cover/Nature Water/2_2.png,MAC_Bench/Nature/Cover/Nature Water/2_2.png,groundtruth,2_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,ave_2,2_1.txt,MAC_Bench/Nature/Cover/Nature Water/2_3.png,MAC_Bench/Nature/Cover/Nature Water/2_3.png,clip,2_3.txt,train
Nature Astronomy,8_11,Which of the following options best describe the cover story?,"Gazing at galaxies from the edge of space
SuperBIT is a wide-field, diffraction-limited optical and near-UV imager of the sky that was designed to travel via the seasonal winds at an altitude of 33 km. Suspended from a scientific balloon rather than a crane, its April 2023 mission took in views of merging galaxy clusters, galaxies, and massive star winds from the stratosphere.
See Massey et al.
Image: Barth Netterfield (University of Toronto). Cover design: Bethany Vukomanovic.",C,MAC_Bench/Nature/Cover/Nature Astronomy/8_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_1.png,vitg,8_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_11.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_11.png,groundtruth,8_11.txt,MAC_Bench/Nature/Cover/Nature Astronomy/6_11.png,MAC_Bench/Nature/Cover/Nature Astronomy/6_11.png,ave_2,6_11.txt,train
BDJ,237_1,Which of the following options best describe the cover story?,"Farewell Stephen Hancocks!
This issue features articles on clinical audit, non-healing extraction socket, and the Surgical Dental Anxiety Scale.

Cover image: From 2022. For this issue, the cover celebrated is one of Stephen Hancocks’ favourites, a pop art style cover published in Volume 233 Issue 10 (25 November 2022). It was part of a series of covers celebrating 150 years of the BDJ through visual storytelling. To mark Stephen’s 20 years’ service as Editor-in-Chief, the editorial team and cover artist decided to create a commemorative final cover featuring Stephen himself in pop art style. He smiles from behind a small mountain of journals while humbly accepting applause for his years of leadership.

Thank you Stephen for your 20 years’ service as Editor-in-Chief of the BDJ, and congratulations on your retirement. We will all miss Stephen, as a colleague, editor, advisor and friend – team meetings will never be the same!
©Tim Marrs, incorporating original artwork by Rachel Jackson",A,MAC_Bench/Nature/Cover/BDJ/237_1.png,MAC_Bench/Nature/Cover/BDJ/237_1.png,groundtruth,237_1.txt,MAC_Bench/Nature/Cover/BDJ/233_3.png,MAC_Bench/Nature/Cover/BDJ/233_3.png,ave_2,233_3.txt,MAC_Bench/Nature/Cover/BDJ/229_6.png,MAC_Bench/Nature/Cover/BDJ/229_6.png,clip,229_6.txt,MAC_Bench/Nature/Cover/BDJ/238_2.png,MAC_Bench/Nature/Cover/BDJ/238_2.png,vith,238_2.txt,val
Nature Astronomy,8_6,Which of the following options best describe the cover story?,"A warm Earth-sized planet ready for characterization
SPECULOOS-3 b is an Earth-sized planet around a cool (2,800 K) red dwarf 16.8 parsecs away. Orbiting in only 17 hours and thus highly irradiated, it is one of the most favourable rocky planets for characterization — for example by JWST — also because of the unusual quiet state of its star.
See Gillon et al.
Image: Lionel Garcia, Flatiron Institute. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,ave_2,1_2.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_3.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_3.png,ave_1,2_3.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_6.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_6.png,groundtruth,8_6.txt,MAC_Bench/Nature/Cover/Nature Astronomy/5_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/5_2.png,clip,5_2.txt,train
ACS ES&T Engineering,2024_4,Which of the following options best describe the cover story?,"is proud to announce the winners of the 2023 Excellence in Review Awards, recognizing outstanding peer reviewers for the journal.",A,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_4.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_5.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_5.png,clip,2023_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_2.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_2.png,ave_2,2023_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_4.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_4.png,ave_3,2022_4.txt,test
Structure,32_11,Which of the following options best describe the cover story?,"On the cover: The study by Mukherjee et al. revealed that the PAS domain of the sensor histidine kinase FlrB of Vibrio
cholerae exhibits a unique architecture and forms a functional dimer. Heme binds FlrB
PAS as the sensory ligand to increase the swimming motility of V. cholerae. Cover
conceptualized by Dr. Jhimli Dasgupta and prepared by Baibhab Chakraborty.",D,MAC_Bench/Cell/Cover/Structure/20_1.png,MAC_Bench/Cell/Cover/Structure/20_1.png,clip,20_1.txt,MAC_Bench/Cell/Cover/Structure/33_2.png,MAC_Bench/Cell/Cover/Structure/33_2.png,vitg,33_2.txt,MAC_Bench/Cell/Cover/Structure/24_12.png,MAC_Bench/Cell/Cover/Structure/24_12.png,vith,24_12.txt,MAC_Bench/Cell/Cover/Structure/32_11.png,MAC_Bench/Cell/Cover/Structure/32_11.png,groundtruth,32_11.txt,val
ACS Chemical Neuroscience,2024_17,Which of the following options best describe the cover story?,The picture shows the serotonergic system highlighted by the GFP reporter on a horizontal brain section of the Tph2GFP knockin mouse line,C,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_22.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_22.png,vitg,2021_22.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,clip,2024_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_17.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_19.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_19.png,vith,2024_19.txt,train
Trends in Biotechnology,42_12,Which of the following options best describe the cover story?,"Mechanical cues play a significant role in wound healing.
In pages 31−42 of this issue, Chang and colleagues discuss cutting-edge advances
in hydrogel-based mechanically active dressings that enable stimuli-responsive
contraction to promote wound closure and healing. Additionally, insightful opinions
on
the future development of mechanically active dressings for personalized wound care
are proposed. Cover image from Le Chang, Huicong Du, Feng Xu, Cuixiang Xu, and
Hao Liu.",D,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,vitg,38_12.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_10.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_10.png,clip,36_10.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/41_3.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/41_3.png,ave_3,41_3.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_12.png,groundtruth,42_12.txt,train
ACS Catalysis,2024_9,Which of the following options best describe the cover story?,"Out of two possible activation modes to provide two sulfonyl radicals, mechanistic studies rule out an energy transfer mechanism and support an oxidative quenching photoredox cycle featuring a sulfinate intermediate.",B,MAC_Bench/ACS/Cover/ACS Catalysis/2017_12.png,MAC_Bench/ACS/Cover/ACS Catalysis/2017_12.png,clip,2017_12.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_9.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2020_1.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_1.png,vitg,2020_1.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2020_5.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_5.png,vith,2020_5.txt,train
ACS Chemical Neuroscience,2024_9,Which of the following options best describe the cover story?,"A hippocampus being drawn: This cover art aims to represent the findings of our study on the therapeutic effects of benfotiamine on Alzheimer's-like neurodegeneration, emphasizing cognitive improvements through the brain insulin pathway. The art was created in CorelDraw X8. The tridimensional c",D,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_14.png,ave_3,2024_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,vitg,2020_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_3.png,clip,2021_3.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_9.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_9.png,groundtruth,2024_9.txt,val
CELL RESEARCH,34_5,Which of the following options best describe the cover story?,"The image depicts the legendary Chinese weapon ‘FangTian Ji’, a formidable combination of a spearhead and two crescent blades. This symbolizes the powerful bacterial two-component anti-phage defense system DUF4297–HerA. DUF4297 and HerA cooperatively assemble to activate their respective nuclease and ATPase activities, effectively eliminating invading phages. See page 545–555 by Qiyin An et al. for details.",B,MAC_Bench/Nature/Cover/CELL RESEARCH/34_3.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_3.png,vith,34_3.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_5.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_5.png,groundtruth,34_5.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png,vitg,34_7.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/29_9.png,MAC_Bench/Nature/Cover/CELL RESEARCH/29_9.png,clip,29_9.txt,test
Bioconjugate Chemistry,2024_4,Which of the following options best describe the cover story?,"A novel FAP-targeting PET probe based on quinolinium was designed and prepared. The targeted binding ability of the probe to FAP was investigated at multiple levels. The results showed that quinolinium FAPI had specific affinity for FAP and had potential for clinical transformation. As the first exploration of charged FAP-targeting probes, quinolinium FAPI fills the gap in this area of research and provides new ideas for the design of new FAPI tracers.",C,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,vitg,2013_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_4.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_4.png,vith,2013_4.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_4.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,clip,2010_3.txt,val
Molecular Pharmaceutics,2025_3,Which of the following options best describe the cover story?,"Fluorescence microscopy reveals core/shell microparticle structures formed using a three-fluid nozzle spray-drying process. Alginate-based microparticles exhibit distinct layers of green (FITC) fluorescence in the core and red (rhodamine B) fluorescence in the shell, highlighting effective encapsulation of Polymyxin B and controlled release properties in antimicrobial drug delivery.  View the article.",D,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,vitg,2020_4.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,clip,2022_8.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_11.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_11.png,ave_1,2022_11.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2025_3.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2025_3.png,groundtruth,2025_3.txt,val
Nature Chemical Engineering,1_12,Which of the following options best describe the cover story?,"Lignin refined
Recalcitrant C–C bonds in lignin limit the monomer yield of current depolymerization strategies that target labile C–O bonds. Now, Emiel Hensen and colleagues present a process based on a bifunctional Pt/zeolite catalyst that selectively cleaves common C–C linkages in lignins, resulting in substantially increased fuel yields from common lignin sources.
See Luo et al. and Subbotina & Samec
Image: Hassan Tahini, ScienceBrush Design. Cover Design: Thomas Phillips.",D,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,vith,1_9.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,clip,1_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,groundtruth,1_12.txt,train
JACS Au,2024_8,Which of the following options best describe the cover story?,"Following a cancer-stem-cell phenotype approach, the discovery of the synthetic small molecule UCM-13369, inspired by microbiota metabolites, is disclosed. Targeting NPM1 protein, the new inhibitor triggers apoptosis in cells from acute myeloid leukemia patients and reduces tumor infiltration in mice. UCM-13369 represents a therapeutic opportunity for NPM1-mutated leukemia, a high-mortality disease. The cover image was created using the generative AI program Midjourney.",B,MAC_Bench/ACS/Cover/JACS Au/2021_8.png,MAC_Bench/ACS/Cover/JACS Au/2021_8.png,clip,2021_8.txt,MAC_Bench/ACS/Cover/JACS Au/2024_8.png,MAC_Bench/ACS/Cover/JACS Au/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/JACS Au/2023_5.png,MAC_Bench/ACS/Cover/JACS Au/2023_5.png,ave_1,2023_5.txt,MAC_Bench/ACS/Cover/JACS Au/2024_10.png,MAC_Bench/ACS/Cover/JACS Au/2024_10.png,ave_2,2024_10.txt,train
Cancer Cell,42_3,Which of the following options best describe the cover story?,"On the cover: Fitzsimons et al. present a comprehensive pan-cancer single-cell RNA-seq atlas of intratumoral B cells,
revealing key associations with responses to immune checkpoint inhibitor therapy and
placing these findings in a spatial context. The cover artwork depicts the identification
of B cells within the tumor microenvironment, illustrating the high-resolution phenotyping
of distinct B cell subsets.",C,MAC_Bench/Cell/Cover/Cancer Cell/32_2.png,MAC_Bench/Cell/Cover/Cancer Cell/32_2.png,clip,32_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_8.png,MAC_Bench/Cell/Cover/Cancer Cell/42_8.png,vith,42_8.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_3.png,MAC_Bench/Cell/Cover/Cancer Cell/42_3.png,groundtruth,42_3.txt,MAC_Bench/Cell/Cover/Cancer Cell/23_5.png,MAC_Bench/Cell/Cover/Cancer Cell/23_5.png,vitg,23_5.txt,train
Molecular Therapy,32_4,Which of the following options best describe the cover story?,"On the cover: The cover is an abstract photograph capturing many and various marvels at the Gardens
by the Bay in Singapore. It symbolizes the variety of targets to be discovered in
the field of cell and gene therapy and the hazy complexity of the methodologies aimed
at their identification. Image credit: Pierluigi Di Pietro.",C,MAC_Bench/Cell/Cover/Molecular Therapy/30_14.png,MAC_Bench/Cell/Cover/Molecular Therapy/30_14.png,vith,30_14.txt,MAC_Bench/Cell/Cover/Molecular Therapy/26_13.png,MAC_Bench/Cell/Cover/Molecular Therapy/26_13.png,clip,26_13.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_4.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_4.png,groundtruth,32_4.txt,MAC_Bench/Cell/Cover/Molecular Therapy/26_12.png,MAC_Bench/Cell/Cover/Molecular Therapy/26_12.png,vitg,26_12.txt,val
NATURE MEDICINE,31_1,Which of the following options best describe the cover story?,"30th anniversary issue: the Future of Medicine
As Nature Medicine turns 30 years old, we will, throughout 2025, be looking at the future of medicine. In this first issue, we turn our attention to next-generation drug discovery.
Image and cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_1.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_1.png,clip,25_1.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_4.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_4.png,vitg,26_4.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_7.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_7.png,vith,25_7.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/31_1.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/31_1.png,groundtruth,31_1.txt,test
Trends in Plant Science,29_8,Which of the following options best describe the cover story?,"This special issue covers a range of topics on the greatest power plants
have to offer, their specialised metabolism. Plants produce a vast number of structurally
diverse class of metabolites (estimates range from 200 000 to 1 000 000) not for the
benefit of vegetative growth or reproductions but to contribute to vital biological
roles
such as signalling or protection. To date many of these roles as well as the underlying
mechanisms remain unexplored and here we shine the spotlight on new advances, such
as the role of phytosterols. Precise communication between the plant and the diverse
microorganisms (from pathogen to mutualist) is essential to induce the corresponding
adaptive response. Christophe Der and colleagues discuss the complicated interaction
between these partners, and the possible involvement of phytosterols. The cover image
represents a plant cell and two microorganisms (a bad and a good guy) playing the
“happy families sterol card game” to define their interactions. Image credit: Christophe
Der and Jerôme Fromentin, UMR Agroecology.",A,MAC_Bench/Cell/Cover/Trends in Plant Science/29_8.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_8.png,groundtruth,29_8.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/21_2.png,MAC_Bench/Cell/Cover/Trends in Plant Science/21_2.png,ave_2,21_2.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_9.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_9.png,clip,29_9.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/25_11.png,MAC_Bench/Cell/Cover/Trends in Plant Science/25_11.png,vitg,25_11.txt,train
ACS ES&T Water,2024_9,Which of the following options best describe the cover story?,"Simulating cadmium (Cd) fate process in lake sediments: Our study reveals a substantial rise in Cd concentration at the surface sediment, impacting benthic organisms. Employing diverse risk assessment methods, we illuminate the ecological consequences of heavy metal fate during acute input events.",D,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_11.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_11.png,ave_1,2024_11.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_1.png,clip,2021_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_11.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_11.png,vitg,2022_11.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_9.png,groundtruth,2024_9.txt,train
Nature Reviews Neurology,20_8,Which of the following options best describe the cover story?,"Stimulating brain circuits, inspired by the Review on p259.
Cover design: Philip Patenall",C,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_3.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_3.png,clip,19_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,vitg,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_8.png,groundtruth,20_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_10.png,ave_2,20_10.txt,train
iScience,27_1,Which of the following options best describe the cover story?,"On the cover: Can artificial intelligence (AI), renowned for its powerful learning
abilities, learn the rich emotional meanings embedded in the lines of Shakespeare's
plays through mere exposure to language? This image representing Ming et al.'s exploration shows an exciting prospect: an AI stepping up the linguistic ladder,
from the void of the senses to the theater of human emotional understanding. The ladder
and void represent the fact that the AI can only access language experience, but this
is sufficient to form a representation of emotion knowledge. Relying on language-based
knowledge representations, the AI has taken its own path to developing emotional competence,
and perhaps one day, it will actually walk into a theater to enjoy Shakespeare's plays.",A,MAC_Bench/Cell/Cover/iScience/27_1.png,MAC_Bench/Cell/Cover/iScience/27_1.png,groundtruth,27_1.txt,MAC_Bench/Cell/Cover/iScience/25_4.png,MAC_Bench/Cell/Cover/iScience/25_4.png,vitg,25_4.txt,MAC_Bench/Cell/Cover/iScience/6_1.png,MAC_Bench/Cell/Cover/iScience/6_1.png,clip,6_1.txt,MAC_Bench/Cell/Cover/iScience/25_9.png,MAC_Bench/Cell/Cover/iScience/25_9.png,vith,25_9.txt,val
Lab Animal,53_8,Which of the following options best describe the cover story?,"Monitoring squirrel hibernation with shredded paper
Detecting torpor-bout duration in heterothermic mammals is usually invasive or inaccurate. To solve this problem, Hutchinson et al. developed a cost-effective, non-invasive method using the paper towel shredding behavior of ground squirrels to detect arousals with 100% accuracy over a long hibernation period.
See Hutchinson et al.
Cover image: Marina Spence. Cover design: Marina Spence.",C,MAC_Bench/Nature/Cover/Lab Animal/51_11.png,MAC_Bench/Nature/Cover/Lab Animal/51_11.png,vith,51_11.txt,MAC_Bench/Nature/Cover/Lab Animal/49_2.png,MAC_Bench/Nature/Cover/Lab Animal/49_2.png,ave_3,49_2.txt,MAC_Bench/Nature/Cover/Lab Animal/53_8.png,MAC_Bench/Nature/Cover/Lab Animal/53_8.png,groundtruth,53_8.txt,MAC_Bench/Nature/Cover/Lab Animal/53_1.png,MAC_Bench/Nature/Cover/Lab Animal/53_1.png,clip,53_1.txt,train
Developmental Cell,59_23,Which of the following options best describe the cover story?,"On the cover: From roots of stem cells to mammary majesty: the image is a visual narrative
of the origin of mammary gland from hair-associated apocrine glands. The tree of life
transforms into a portrait of a face, with roots as embryonic stem cells (white) that
differentiate into branched mammary glands, represented by the hair. To learn more
about how to generate the mammary lineage in 3D organoids by directed differentiation
of mouse ES cells, see Sahu et al. Image credit: Sounak Sahu, Joseph Meyer, and Allen Kane.",D,MAC_Bench/Cell/Cover/Developmental Cell/59_10.png,MAC_Bench/Cell/Cover/Developmental Cell/59_10.png,clip,59_10.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_24.png,MAC_Bench/Cell/Cover/Developmental Cell/59_24.png,ave_1,59_24.txt,MAC_Bench/Cell/Cover/Developmental Cell/43_4.png,MAC_Bench/Cell/Cover/Developmental Cell/43_4.png,vitg,43_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_23.png,MAC_Bench/Cell/Cover/Developmental Cell/59_23.png,groundtruth,59_23.txt,train
Nature Reviews Earth & Environment,5_3,Which of the following options best describe the cover story?,"Lake ice has witnessed considerable changes in its phenology, but less is known about ice quality—the ratio of black ice to white ice. This Review assesses the changes in lake ice quality and its ecosystem services, noting diminished ice quality in observations and projections.
Image credit: robertharding / Alamy Stock Photo. Cover design: Carl Conway.",B,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_3.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_3.png,groundtruth,5_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_5.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_5.png,ave_2,3_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_11.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_11.png,ave_1,3_11.txt,train
NATURE REVIEWS MICROBIOLOGY,22_9,Which of the following options best describe the cover story?,"Machine learning for microbiologists, inspired by the Review on p191.
Cover design: Philip Patenall.",A,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_9.png,groundtruth,22_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/11_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/11_4.png,vith,11_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/17_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/17_1.png,clip,17_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_9.png,vitg,19_9.txt,val
Acta Pharmacologica Sinica,46_2,Which of the following options best describe the cover story?,"Cover Credit: Schematic illustration of the potential mechanisms underlying mitophagy against hypoxia-ischemia-induced neuronal ferroptosis. In neonatal rat HIBD, mitophagy is activated as a protective response to maintain mitochondrial homeostasis and energy metabolism. BNIP3-dependent mitophagy mediated by Tat-SPK2 peptide maintains iron and redox homeostasis by facilitating P62-KEAP1-NRF2 pathway, thereby ameliorating lipid peroxidation and neuronal ferroptosis. (DOI 10.1038/s41401-024-01365-x). See the article in pages 33–51",D,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_3.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_3.png,clip,43_3.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_10.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_10.png,vith,43_10.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,vitg,45_9.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/46_2.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/46_2.png,groundtruth,46_2.txt,test
Developmental Cell,59_24,Which of the following options best describe the cover story?,"On the cover: This image shows a developing human forebrain organoid at day 60, which
has a “tree-like” structure. Neural progenitor cells are marked by SOX2 (green), lysosomes
are marked by LAMP1 (white), and nuclei are marked by DAPI (blue). During the development
of embryonic neocortex, there are abundant endolysosomes in the neural progenitor
cells near the ventricle. Using our analogy to a tree, they function like roots, absorbing
nutrients from the cerebrospinal fluid in the ventricle to maintain the proliferative
capacity of the neural progenitor cells. As differentiated intermediate progenitor
cells and neurons migrate upward along the “trunk,” the cortical plate is formed.
To learn more about how lysosomal dynamics regulate neurogenesis, see Zou et al. Image credit: Yuqing Lv and Wenzheng Zou.",D,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,clip,59_20.txt,MAC_Bench/Cell/Cover/Developmental Cell/30_1.png,MAC_Bench/Cell/Cover/Developmental Cell/30_1.png,vith,30_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/37_6.png,MAC_Bench/Cell/Cover/Developmental Cell/37_6.png,vitg,37_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_24.png,MAC_Bench/Cell/Cover/Developmental Cell/59_24.png,groundtruth,59_24.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_11,Which of the following options best describe the cover story?,"‘Hair control’, inspired by the Review on p87
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_9.png,vitg,24_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_11.png,groundtruth,25_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,clip,24_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_8.png,vith,22_8.txt,train
Cell Stem Cell,31_9,Which of the following options best describe the cover story?,"On the cover: Early diagnosis of preterm brain injuries remains a significant challenge.
In this issue, Epstein et al. reveal an injury to the subventricular zone in preterm infants that predicts cerebral
palsy and motor impairment much earlier than is currently feasible in babies. The
injury is visible using cranial ultrasound. The cover art, painted by Cassidy Logan,
shows a fortune teller who is predicting the neurologic outcome of a preterm infant
using a crystal ball. Her vision of the child's likely health outcome is informed
by the ultrasound signals taken at the subventricular zone where the integrity of
the neural stem cell niche leads to production and migration of progenitor cells for
the developing brain.",D,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,vitg,6_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,vith,31_3.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/7_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/7_4.png,clip,7_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_9.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_9.png,groundtruth,31_9.txt,train
Nature Reviews Electrical Engineering,1_3,Which of the following options best describe the cover story?,"Low-Earth orbit (LEO) broadband communications and their integration with 5G and 6G cellular networks are at the forefront of the new space era. The cover shows a representation of a LEO constellation. See Lagunas
Cover design: Sam Whitham",B,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_11.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_11.png,clip,1_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_3.png,groundtruth,1_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_12.png,vitg,1_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,ave_3,1_7.txt,val
Trends in Genetics,41_3,Which of the following options best describe the cover story?,"Sex chromosomes can cause expression imbalances between males
and females that are often corrected through dosage compensation. In this issue,
Kalita and Keller Valsecchi review our current understanding of dosage compensation
across diverse insect species beyond traditional model organisms. They discuss the
evolutionary dynamics of sex chromosomes, the variety of molecular mechanisms that
achieve balanced expression, and propose approaches to uncover regulatory pathways
in non-model insects. Illustration by Agata Kalita.",B,MAC_Bench/Cell/Cover/Trends in Genetics/41_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/41_1.png,vitg,41_1.txt,MAC_Bench/Cell/Cover/Trends in Genetics/41_3.png,MAC_Bench/Cell/Cover/Trends in Genetics/41_3.png,groundtruth,41_3.txt,MAC_Bench/Cell/Cover/Trends in Genetics/35_9.png,MAC_Bench/Cell/Cover/Trends in Genetics/35_9.png,clip,35_9.txt,MAC_Bench/Cell/Cover/Trends in Genetics/39_6.png,MAC_Bench/Cell/Cover/Trends in Genetics/39_6.png,ave_3,39_6.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_8,Which of the following options best describe the cover story?,"RNAi-based drug design, inspired by the Review on p341.
Cover design: S. Harris",C,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_1.png,vith,19_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_8.png,groundtruth,23_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_5.png,vitg,20_5.txt,train
NATURE ENERGY,9_9,Which of the following options best describe the cover story?,"Clean cooking transition experiences
Adapting to cleaner cooking fuels from more polluting options may be experienced differently by different groups across various stages of the energy transition. Kar et al. analyse survey data on household-level energy use in Ghana as the country shifts towards cleaner cooking fuels. Given wide heterogeneity, they propose a stage-based framework to support policy interventions.
See Kar et al.
Image: Kypros / Getty Images. Cover design: Thomas Phillips",D,MAC_Bench/Nature/Cover/NATURE ENERGY/4_4.png,MAC_Bench/Nature/Cover/NATURE ENERGY/4_4.png,ave_2,4_4.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/1_2.png,MAC_Bench/Nature/Cover/NATURE ENERGY/1_2.png,ave_1,1_2.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/5_1.png,MAC_Bench/Nature/Cover/NATURE ENERGY/5_1.png,clip,5_1.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_9.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_9.png,groundtruth,9_9.txt,train
BDJ,237_7,Which of the following options best describe the cover story?,"In this issue
This issue features articles on smoking cessation, MIOC, and cocaine-induced destruction of the palate.

Cover image: From 2016. To celebrate the birth of the Portfolio and mark the first anniversary of the launch of its newest member, the open access online-only journal BDJ Open, we designed a cover series highlighting the letters B, D and J in collaboration with long-time editorial board member, Professor Damien Walmsley. The BDJ element represented in the cover of this issue is, perhaps somewhat controversially, composed of cake crafted in the letters by editorial team member at the time Ruth Doherty. Although appearing as Volume 221 Issue 7 (7 October 2016), it was actually baked and consumed in July of that year at a delicious editorial board meeting!
©Tim Marrs",B,MAC_Bench/Nature/Cover/BDJ/227_9.png,MAC_Bench/Nature/Cover/BDJ/227_9.png,vith,227_9.txt,MAC_Bench/Nature/Cover/BDJ/237_7.png,MAC_Bench/Nature/Cover/BDJ/237_7.png,groundtruth,237_7.txt,MAC_Bench/Nature/Cover/BDJ/229_3.png,MAC_Bench/Nature/Cover/BDJ/229_3.png,vitg,229_3.txt,MAC_Bench/Nature/Cover/BDJ/233_2.png,MAC_Bench/Nature/Cover/BDJ/233_2.png,clip,233_2.txt,test
Current Biology,34_2,Which of the following options best describe the cover story?,"On the cover: A group of yellow-billed long-tailed finches (Poephila acuticauda) perch on a tree branch. In this issue, Hooper et al. demonstrate the role of selection in the evolution of bill coloration, a carotenoid-based
color trait that distinguishes a pair of hybridizing subspecies. Yellow alleles, like
the ones carried by the birds in this image, regulate the oxidative ketolation reaction
required by vertebrates to metabolize red carotenoid pigments from dietary precursors.
Adaptive introgression of these derived and largely recessive yellow alleles is ongoing
and suggests that the frequent evolutionary transitions between carotenoid color states
observed in nature may have a simple genetic basis. Photograph © Col Roberts; used
with permission.",B,MAC_Bench/Cell/Cover/Current Biology/18_1.png,MAC_Bench/Cell/Cover/Current Biology/18_1.png,ave_2,18_1.txt,MAC_Bench/Cell/Cover/Current Biology/34_2.png,MAC_Bench/Cell/Cover/Current Biology/34_2.png,groundtruth,34_2.txt,MAC_Bench/Cell/Cover/Current Biology/21_5.png,MAC_Bench/Cell/Cover/Current Biology/21_5.png,vith,21_5.txt,MAC_Bench/Cell/Cover/Current Biology/32_6.png,MAC_Bench/Cell/Cover/Current Biology/32_6.png,clip,32_6.txt,train
ACS Applied Bio Materials,2024_8,Which of the following options best describe the cover story?,"Hollow, mesoporous CeO2 nanoparticles, crafted via staged-shape templating, and functionalized with polydopamine, chlorine e6, and a cascade enzyme system demonstrate remarkable efficacy in killing human glioblastoma cells through combinatorial photothermal, photodynamic, chemodynamic, and starvation mechanisms. Synergy-driven 90% cell death in vitro suggests the potential as a potent cancer therapy nanoplatform.",A,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_8.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_6.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_12.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_12.png,vitg,2020_12.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_6.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_6.png,clip,2022_6.txt,train
One Earth,7_1,Which of the following options best describe the cover story?,"On the cover: Soil, the earth beneath our feet, provides essential ecological services
for all life on Earth, but it is under immense pressure from anthropogenic activities.
Yet before we can effectively manage, protect, and restore our soils, we must first
develop a comprehensive understanding of soil health. Getty, Kami (Kuo, Jia-Wei).",D,MAC_Bench/Cell/Cover/One Earth/2_4.png,MAC_Bench/Cell/Cover/One Earth/2_4.png,ave_2,2_4.txt,MAC_Bench/Cell/Cover/One Earth/6_1.png,MAC_Bench/Cell/Cover/One Earth/6_1.png,vith,6_1.txt,MAC_Bench/Cell/Cover/One Earth/2_3.png,MAC_Bench/Cell/Cover/One Earth/2_3.png,clip,2_3.txt,MAC_Bench/Cell/Cover/One Earth/7_1.png,MAC_Bench/Cell/Cover/One Earth/7_1.png,groundtruth,7_1.txt,train
Nature Reviews Bioengineering,2_2,Which of the following options best describe the cover story?,"Viruses and virus-like particles can be repurposed as tools and carrier vehicles for intratumoural immunotherapy to elicit anti-tumour immunity and induce systemic anti-tumour responses at distant non-injected sites. See Anthony O. Omole et al
Cover image: Simon Bradbrook",C,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_8.png,ave_3,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,vith,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_2.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_2.png,groundtruth,2_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,clip,1_10.txt,test
BDJ,238_2,Which of the following options best describe the cover story?,"In this issue
This issue features articles on antibiotic prophylaxis, indirect pulp capping, and artificial intelligence.

Cover image: Teamwork. No one-man band here. What’s a practice or procedure without the team behind it?
My venture into illustrations originated as a fun and creative way to relax and learn anatomy and instruments during my commutes to and from my dental foundation year. I was fond of art growing up and had strongly considered going into film-set design and art foundation opposed to the sciences. I wanted to get back into drawing after finishing dental school and I found digital dental illustrations through this.
©Pippasha Khan @DrPippa.K",A,MAC_Bench/Nature/Cover/BDJ/238_2.png,MAC_Bench/Nature/Cover/BDJ/238_2.png,groundtruth,238_2.txt,MAC_Bench/Nature/Cover/BDJ/233_4.png,MAC_Bench/Nature/Cover/BDJ/233_4.png,vitg,233_4.txt,MAC_Bench/Nature/Cover/BDJ/237_5.png,MAC_Bench/Nature/Cover/BDJ/237_5.png,vith,237_5.txt,MAC_Bench/Nature/Cover/BDJ/233_2.png,MAC_Bench/Nature/Cover/BDJ/233_2.png,clip,233_2.txt,train
Accounts of Chemical Research,2024_20,Which of the following options best describe the cover story?,"In this Account, we summarize our contributions to the development of new difluorocarbene reagents and their applications in organic synthesis since 2006. Silanes TMSCF2X (TMS = trimethylsilyl and X = Br, F, and Cl) have stood out as privileged among all known difluorocarbene reagents, owing to their rich activation modes of releasing difluorocarbene under different reaction conditions (such as under basic/acidic/neutral conditions, at a wide range of temperatures, and in different solvents). As shown in the cover picture, the dandelion (TMSCF2X) can easily release its seeds (:CF2) in different environments (under different reaction conditions), and the seeds (:CF2) have strong vitality (suitable for a wide range of reactions).",B,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2010_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2010_2.png,vith,2010_2.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_20.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_20.png,groundtruth,2024_20.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2016_6.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2016_6.png,vitg,2016_6.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_1.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_1.png,clip,2019_1.txt,train
Trends in Ecology & Evolution,39_6,Which of the following options best describe the cover story?,"Migratory animals, such as the blue wildebeest (Connochaetes taurinus)
shown here, transport parasites along their migratory routes. On pages 625–633,
Jason Donaldson and colleagues discuss how the trophic effects of migrants can alter
parasite dynamics for residents. They develop a framework to better determine migrant
trophic and transport effects on resident animal parasite prevalence. Photo credit:
Jason Donaldson.",A,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_6.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_6.png,groundtruth,39_6.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_8.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_8.png,clip,29_8.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/31_3.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/31_3.png,vitg,31_3.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/37_2.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/37_2.png,ave_3,37_2.txt,train
Journal of Medicinal Chemistry,2024_8,Which of the following options best describe the cover story?,–,B,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_2.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_2.png,vitg,2017_2.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_8.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/1998_14.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/1998_14.png,ave_2,1998_14.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/1997_23.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/1997_23.png,clip,1997_23.txt,train
Nature Plants,11_1,Which of the following options best describe the cover story?,"Expanding the diversity of sweet potato
Sweet potato (Ipomoea batatas (L.) Lam.) is a hexaploid crop with an annual production in excess of 80 million tonnes. Detailed sequencing and phenotyping of 294 accessions showed that variations in their principal agronomic traits (expanded tuberous roots and orange colour) result from increased dosage of two genes: the expansin gene IbEXPA4 and the Orange gene.
See Zhang, X. et al.
Image: Zhangjun Fei, Boyce Thompson Institute, Ithaca, NY, USA. Cover design: Erin Dewalt",C,MAC_Bench/Nature/Cover/Nature Plants/8_13.png,MAC_Bench/Nature/Cover/Nature Plants/8_13.png,clip,8_13.txt,MAC_Bench/Nature/Cover/Nature Plants/8_11.png,MAC_Bench/Nature/Cover/Nature Plants/8_11.png,vitg,8_11.txt,MAC_Bench/Nature/Cover/Nature Plants/11_1.png,MAC_Bench/Nature/Cover/Nature Plants/11_1.png,groundtruth,11_1.txt,MAC_Bench/Nature/Cover/Nature Plants/4_9.png,MAC_Bench/Nature/Cover/Nature Plants/4_9.png,vith,4_9.txt,train
Molecular Plant,17_1,Which of the following options best describe the cover story?,"On the cover: In this issue, Liu et al. show that MYB3R-like interacts with the methyltransferase
RID2 to maintain the 5’ cap structure of WUSCHEL (WUS) mRNA and protect it from degradation. As the most important stem cell regulator,
WUSCHEL maintains the accuracy of protein synthesis in stem cells by repressing key
components in protein folding to prevent the reuse of refolded proteins. Upon heat
stress, which results in extensive increases of misfolded proteins in stem cells,
the MYB3R-like/RID2 module is suppressed to decap WUS mRNA and reduce its stability. This releases the inhibition of protein folding capacity
in stem cells to eliminate misfolded proteins and allows stem cell survival at high
temperatures. The cover image is designed by the inspiration from the ancient Chinese
myth “Journey to the West”. After the havoc in heaven, the Monkey King is captured
and sealed in a magic alchemy furnace. The Monkey King needs to break the shackles
by kicking over the alchemy furnace to save himself from fire, just as stem cells
need to reduce WUS transcripts by decapping nascent WUS mRNAs to protect themselves under heat stress. Image by Sumei Liu.",C,MAC_Bench/Cell/Cover/Molecular Plant/16_1.png,MAC_Bench/Cell/Cover/Molecular Plant/16_1.png,vitg,16_1.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_2.png,MAC_Bench/Cell/Cover/Molecular Plant/17_2.png,vith,17_2.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_1.png,MAC_Bench/Cell/Cover/Molecular Plant/17_1.png,groundtruth,17_1.txt,MAC_Bench/Cell/Cover/Molecular Plant/11_7.png,MAC_Bench/Cell/Cover/Molecular Plant/11_7.png,clip,11_7.txt,train
Trends in Cognitive Sciences,28_4,Which of the following options best describe the cover story?,"Exploring the contrast in confidence levels regarding the existence of
invisible scientific phenomena, such as oxygen, and invisible religious phenomena,
like God, raises questions about the role of direct experience versus testimony in
shaping beliefs across different domains. Conventional explanations often attribute
belief formation in scientific phenomena to direct experience and belief formation
in religious phenomena to testimony. In this issue of Trends in Cognitive Sciences,
Ma and colleagues propose that beliefs in both scientific and religious domains are
predominantly shaped by testimony, challenging the traditional view. By highlighting
the influence of testimony over direct experience, they underscore the significance
of
credibility and cultural input in shaping individuals' ontological beliefs across
domains.
Cover image from Fotosearch/Getty Images.",D,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_7.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_7.png,ave_1,18_7.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/24_8.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/24_8.png,ave_2,24_8.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_13.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_13.png,clip,17_13.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_4.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_4.png,groundtruth,28_4.txt,train
ACS Applied Engineering Materials,2024_8,Which of the following options best describe the cover story?,Both direct ink writing and selective laser melting techniques offer the ability to create immiscible metal matrix composites while also allowing for precise shaping of objects. These composites enhance wear resistance and improve thermal conductivity in materials.,C,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_7.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_7.png,vith,2023_7.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,vitg,2024_3.txt,val
Nature Neuroscience,27_9,Which of the following options best describe the cover story?,"GluK2 detects cold
The molecular identity of cold sensors in peripheral somatosensory neurons remains unclear. Cai et al. report that GluK2, a kainate-type glutamate receptor that mediates synaptic transmission in the brain, is co-opted as a cold sensor in the periphery. The cover art depicts snow and ice adhering to the ends of branches, symbolizing the role of peripheral sensory nerve endings, distant from the soma (shown in the background), as the primary detectors of cold.
See Cai et al.
Image and cover design: Rajani Arora. Cover design: Debbie Maizels.",B,MAC_Bench/Nature/Cover/Nature Neuroscience/14_3.png,MAC_Bench/Nature/Cover/Nature Neuroscience/14_3.png,clip,14_3.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_9.png,groundtruth,27_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/23_12.png,MAC_Bench/Nature/Cover/Nature Neuroscience/23_12.png,vitg,23_12.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/20_6.png,MAC_Bench/Nature/Cover/Nature Neuroscience/20_6.png,vith,20_6.txt,val
Nature Synthesis,3_6,Which of the following options best describe the cover story?,"Electroreduction of CO2 for C–X bond formation
Electrochemical cross-coupling is a possible sustainable synthetic route for important chemicals containing carbon–heteroatom bonds. This Review outlines different coupling strategies and discusses how the topic is approached from the perspectives of theoretical modelling, electrolyser construction, and technoeconomic analysis.
See Kornienko et al.
Image: Nikolay Kornienko, University of Bonn. Cover design: Amie Fernandez",A,MAC_Bench/Nature/Cover/Nature Synthesis/3_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_6.png,groundtruth,3_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_4.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_4.png,clip,3_4.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,ave_2,3_9.txt,train
Nature Plants,10_9,Which of the following options best describe the cover story?,"Symbiosis in time and space
The symbiotic interaction of arbuscular mycorrhizal fungi with plant roots enables the mutual exchange of carbon for nutrients such as phosphate. The course of this highly dynamic relationship can be followed by a combination of single-cell and spatial transcriptomics.
See Serrano, K. et al.
Image: Kent Leech, Lawrence Berkeley National Laboratory Creative Services. Cover design: Erin Dewalt",D,MAC_Bench/Nature/Cover/Nature Plants/5_2.png,MAC_Bench/Nature/Cover/Nature Plants/5_2.png,vith,5_2.txt,MAC_Bench/Nature/Cover/Nature Plants/4_9.png,MAC_Bench/Nature/Cover/Nature Plants/4_9.png,clip,4_9.txt,MAC_Bench/Nature/Cover/Nature Plants/9_6.png,MAC_Bench/Nature/Cover/Nature Plants/9_6.png,vitg,9_6.txt,MAC_Bench/Nature/Cover/Nature Plants/10_9.png,MAC_Bench/Nature/Cover/Nature Plants/10_9.png,groundtruth,10_9.txt,train
Journal of Agricultural and Food Chemistry,2025_6,Which of the following options best describe the cover story?,Starch–lipid complexes (type 5 RS) can effectively alleviate experimentally induced colitis in mice by modulating gut microbiota,C,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_18.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_18.png,vitg,2021_18.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2023_1.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_6.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2023_49.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2023_49.png,ave_1,2023_49.txt,train
CELL RESEARCH,34_11,Which of the following options best describe the cover story?,"Neural connectome mapping describes how different types of neurons connect with each other and organs in the body. This cartoon (illustrated by Evelyn Xiaoya Zhao) shows a densely-stacked neuron network linked by dendrites and axons, together with nonneuronal cells including glial cells, endothelium, pericytes and many others. A new tissue clearing pipeline, TESOS, is designed to image a complete projection course of individual sensory neurons from mouse digits to the spinal cord. See page 124–139 by Yating Yi et al. for details.",B,MAC_Bench/Nature/Cover/CELL RESEARCH/32_7.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_7.png,vitg,32_7.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_11.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_11.png,groundtruth,34_11.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_4.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_4.png,vith,34_4.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_8.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_8.png,clip,32_8.txt,train
Med,5_2,Which of the following options best describe the cover story?,"On the cover: Obesity is a known risk factor for some types of cancers. With the global
rise in overweight and obesity rates, it is important to understand the impact on
cancer incidence. In this issue of Med, Liu et al present an analysis of data from a population-based cancer registry in China covering
14.4 million individuals between 2007–2021. Worryingly, they note an increase in obesity-related
cancers, especially among younger adults. These findings highlight the need for public
health interventions and policies to address obesity as a risk factor and lower premature
mortality rates. Cover credit: d3sign via Moments/Getty Images.",B,MAC_Bench/Cell/Cover/Med/4_6.png,MAC_Bench/Cell/Cover/Med/4_6.png,vith,4_6.txt,MAC_Bench/Cell/Cover/Med/5_2.png,MAC_Bench/Cell/Cover/Med/5_2.png,groundtruth,5_2.txt,MAC_Bench/Cell/Cover/Med/3_1.png,MAC_Bench/Cell/Cover/Med/3_1.png,clip,3_1.txt,MAC_Bench/Cell/Cover/Med/5_3.png,MAC_Bench/Cell/Cover/Med/5_3.png,vitg,5_3.txt,val
Nature Human Behaviour,9_1,Which of the following options best describe the cover story?,"Pupil literacy in LMICs
Although school enrolment has expanded rapidly around the world since the 1950s, enrolment does not necessarily translate to meaningful increases in literacy. Crawford et al. report data from over half a million pupils from 48 low- and middle-income countries (LMICs) that show that pupils across the first three instructional years are failing to acquire the most basic skills that underpin reading comprehension. The authors suggest that systematic phonics programmes are needed to reach literacy goals.
See Crawford et al. See also News & Views by Kaffenberger
Image: Malte Mueller/fStop/Getty. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_10.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_10.png,clip,4_10.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/9_1.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_2.png,vitg,5_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_9.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_9.png,vith,7_9.txt,train
Nature Reviews Electrical Engineering,1_6,Which of the following options best describe the cover story?,"Textile displays are promising for next-generation displays owing to their capabilities of weaving electroluminescent units directly into the interwoven points of polymer composite fibres. The cover image shows the textile display. See Wang et al.
Cover design: Sam Whitham",D,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,ave_3,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,clip,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,ave_2,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_6.png,groundtruth,1_6.txt,train
Journal of Agricultural and Food Chemistry,2025_2,Which of the following options best describe the cover story?,"This cover highlights the use of nitrogen-fixing bacteria in crops, emphasizing that, through genetic modification, these bacteria can provide crops with an increased source of nitrogen. It depicts a scene of a green wheat field adjacent to a patch of yellow soil. Within the wheat field, a plant is illustrated with red lines extending from its roots into the soil, symbolizing the process of nutrient absorption. The text ""NH4+"" on the image further underscores the focus on nitrogen, emphasizing the role of nitrogen-fixing bacteria in enhancing crop nutrition through genetic engineering. Additionally, it is worth noting that the partial elements of this cover were created using an Artificial Intelligence-based image generation tool named ""Doubao"".",C,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_38.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_38.png,ave_2,2021_38.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_2.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_35.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_35.png,ave_1,2021_35.txt,test
Biomacromolecules,2024_10,Which of the following options best describe the cover story?,"The hierarchical evolution of the development of one-component multifunctional sequence-defined ionizable amphiphilic Janus dendrimers (IAJDs) co-assembling with mRNA into dendrimersome nanoparticles (DNPs) targeting in vivo delivery to various organs is illustrated. This process started with the discovery of the self-assembly of helical rodlike and spherical helices virus-like supramolecular assemblies self-organizing periodic and quasiperiodic arrays including Frank–Kasper and quasicrystals and biological membrane mimics, and continued with elucidation of mechanisms, to unravel a one-component viral-like programmed synthetic vector for nanomedicine.",C,MAC_Bench/ACS/Cover/Biomacromolecules/2022_5.png,MAC_Bench/ACS/Cover/Biomacromolecules/2022_5.png,vith,2022_5.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_4.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_4.png,clip,2021_4.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_2.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_2.png,vitg,2021_2.txt,train
Nature Synthesis,3_7,Which of the following options best describe the cover story?,"Cyclodextrins through the looking glass
The syntheses of mirror-image versions of three naturally occurring cyclodextrins from simple monosaccharide building blocks are reported. The synthetic strategy involves 1,2-cis-L-glucosylation, one-pot glycosylation, and diastereoselective cyclization, providing the cyclo-oligosaccharides in up to half-gram quantities.
See Wu et al.
Image: Kaili Chien at SHO SHO Design Ltd. Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/Nature Synthesis/1_2.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_2.png,ave_1,1_2.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_7.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_7.png,groundtruth,3_7.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,clip,1_8.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_6.png,vitg,1_6.txt,train
Nature Aging,4_5,Which of the following options best describe the cover story?,"Mitochondrial and nuclear gene co-evolution
In this issue, Mei Tao, Jiani Chen, Chunlai Cui, Yandong Xu et al. analyze the co-evolution of mitochondrial and nuclear genomes in 472 insects and identify a group of non-mitochondria-targeted nuclear genes that potentially co-function with mtOXPHOS genes. Their discovery includes the uncharacterized gene CG11837 — a putative ortholog of human DIMT1 — that regulates insect lifespan. The cover image shows a collection of insect species, illustrating the diversity of animals in this class that contributed to this study.
See Tao et al.
Image: Lauren Heslop. Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Aging/3_2.png,MAC_Bench/Nature/Cover/Nature Aging/3_2.png,vith,3_2.txt,MAC_Bench/Nature/Cover/Nature Aging/3_7.png,MAC_Bench/Nature/Cover/Nature Aging/3_7.png,vitg,3_7.txt,MAC_Bench/Nature/Cover/Nature Aging/4_5.png,MAC_Bench/Nature/Cover/Nature Aging/4_5.png,groundtruth,4_5.txt,MAC_Bench/Nature/Cover/Nature Aging/4_9.png,MAC_Bench/Nature/Cover/Nature Aging/4_9.png,clip,4_9.txt,train
Journal of Chemical Theory and Computation,2024_21,Which of the following options best describe the cover story?,"The PARCH scale is a tool for calculating the hydropathy of amino acid residues as a function of a protein’s nanoscale topography, such as bumps, crevices, cavities, clefts, pockets, and channels. This computationally inexpensive method can compare hydropathies of the different protein surfaces and quantify the effect of point mutations.",D,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2016_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2016_1.png,clip,2016_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,vitg,2021_12.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,vith,2024_17.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_21.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_21.png,groundtruth,2024_21.txt,train
Nature Catalysis,7_5,Which of the following options best describe the cover story?,"Deracemization by electrical energy
Accessing optically pure compounds by deracemization is usually accomplished by chemical, photo- or mechanical energy. In their work, the authors present an electrocatalytic deracemization method for secondary alcohols by immobilizing a Rh catalyst on the cathode, which prioritizes its reduction over the Ir catalyst.
See Zhu et al.
Image: Jianchun Wang, Southern University of Science and Technology. Cover design: Alex Whitworth",C,MAC_Bench/Nature/Cover/Nature Catalysis/2_5.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Catalysis/4_9.png,MAC_Bench/Nature/Cover/Nature Catalysis/4_9.png,ave_2,4_9.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_5.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_5.png,groundtruth,7_5.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_9.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_9.png,clip,2_9.txt,train
Nature Chemical Biology,20_5,Which of the following options best describe the cover story?,"Computational protein design
Development in computational tools enables the prediction of protein structures and de novo design of proteins with new features or desired functions. The cover image depicts the computational design and engineering of all-parallel and antiparallel α-helical barrel proteins with functionalizable channels.
See Albanese et al.
Image: Rokas Petrenas and Katherine Albanese, University of Bristol. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_1.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_1.png,vitg,13_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_9.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_9.png,vith,20_9.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/19_5.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/19_5.png,clip,19_5.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_5.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_5.png,groundtruth,20_5.txt,val
Nature Ecology & Evolution,8_10,Which of the following options best describe the cover story?,"200 years of dinosaurs
2024 marks 200 years since William Buckland presented Megalosaurus, arguably the first dinosaur to have been named by science. Depictions have changed since Mary Morland Buckland’s sketches of the Megalosaurus jaw accompanied her husband’s work, and a wealth of palaeontological and palaeoecological discoveries in the interim two centuries lie behind Mark Witton’s 21st-century take on a megalosaur attacking its sauropod prey in a lush Jurassic forest landscape.
See Editorial
Image: Mark P. Witton. Cover Design: Allen Beattie.",C,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_10.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_10.png,vith,4_10.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_1.png,vitg,5_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_10.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_10.png,groundtruth,8_10.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_12.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_12.png,clip,4_12.txt,train
Crystal Growth & Design,2024_15,Which of the following options best describe the cover story?,"In crystalline solids, especially in rotaxanes, solvates are common as a result of intrinsic topologies. Our goal is to explore solvent roles in rotaxane crystallization using the supramolecular cluster methodology and tetralactam macrocycle-based rotaxanes. Understanding solvate formation is crucial for applying molecular machines in the solid state.",B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_5.png,vith,2018_5.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_15.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_15.png,groundtruth,2024_15.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,vitg,2019_11.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,clip,2024_8.txt,train
ACS ES&T Water,2024_6,Which of the following options best describe the cover story?,Read the recent Collection on Wastewater-Based Epidemiology,C,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_5.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_5.png,ave_2,2022_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_8.png,ave_1,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_6.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_2.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_2.png,clip,2022_2.txt,train
Science Robotics,9_87,Which of the following options best describe the cover story?,ONLINE COVER Special Issue on Magnetic Robots for Medical Applications. Accessing the brain promptly to treat conditions such as acute ischemic stroke is a challenge for clinicians. Dreyfus et al. developed a dexterous continuum robot driven by magnetic fields for endovascular navigation. The continuum robot was developed with a helical outer surface to enable forward motion and an articulated magnetic tip to facilitate steerability in tortuous blood vessels. They demonstrated the potential to reach targets in facial and maxillary arteries in vivo. This month’s cover is an image of the dexterous continuum robot navigating within a phantom vasculature model.  Credit: Marco Rosasco Photography,B,MAC_Bench/Science/Cover/Science Robotics/2_8.png,MAC_Bench/Science/Cover/Science Robotics/2_8.png,vith,2_8.txt,MAC_Bench/Science/Cover/Science Robotics/9_87.png,MAC_Bench/Science/Cover/Science Robotics/9_87.png,groundtruth,9_87.txt,MAC_Bench/Science/Cover/Science Robotics/7_65.png,MAC_Bench/Science/Cover/Science Robotics/7_65.png,vitg,7_65.txt,MAC_Bench/Science/Cover/Science Robotics/3_18.png,MAC_Bench/Science/Cover/Science Robotics/3_18.png,clip,3_18.txt,train
NATURE IMMUNOLOGY,25_8,Which of the following options best describe the cover story?,"Regulating NK cell effector function
Li et al. identify the transcription factor MEF2C as essential for human natural killer (NK) cell function and viral immunity in mice and humans. This control is exerted by regulation of lipid metabolism, and deficiency in MEF2C can be overcome by supplementation with oleic acid.
See Li et al.
Image credit: Adalia Zhou, UCLA. Cover design: Amie Fernandez",D,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/23_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/23_12.png,vitg,23_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/7_6.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/7_6.png,vith,7_6.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_3.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_3.png,clip,10_3.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_8.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_8.png,groundtruth,25_8.txt,val
Organometallics,2025_1,Which of the following options best describe the cover story?,"Phenyl pulling in the transmetalation universe: The elementary step of transmetalation from boron to copper is represented as a fierce battle of the two elements for a phenyl group. This contest is observed, although not in outer space, in the vacuum of a mass spectrometer. The gas-phase approach permits the exclusion of interfering effects present in solution and provides fundamental mechanistic insights into B–",D,MAC_Bench/ACS/Cover/Organometallics/2024_17.png,MAC_Bench/ACS/Cover/Organometallics/2024_17.png,vith,2024_17.txt,MAC_Bench/ACS/Cover/Organometallics/2024_15.png,MAC_Bench/ACS/Cover/Organometallics/2024_15.png,clip,2024_15.txt,MAC_Bench/ACS/Cover/Organometallics/2024_22.png,MAC_Bench/ACS/Cover/Organometallics/2024_22.png,vitg,2024_22.txt,MAC_Bench/ACS/Cover/Organometallics/2025_1.png,MAC_Bench/ACS/Cover/Organometallics/2025_1.png,groundtruth,2025_1.txt,val
Nature Catalysis,7_8,Which of the following options best describe the cover story?,"Bias-free ammonia
In their work, Ji-Wook Jang and colleagues couple an efficient lead halide perovskite photocathode for nitrate reduction to a glycerol oxidation anode for bias-free ammonia production with a photocurrent density greater than 20 mA cm–2.
See Tayyebi et al.
Image: CUBE3D Graphic / Younghee Lee. Cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/Nature Catalysis/3_6.png,MAC_Bench/Nature/Cover/Nature Catalysis/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_6.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_6.png,vitg,7_6.txt,MAC_Bench/Nature/Cover/Nature Catalysis/6_2.png,MAC_Bench/Nature/Cover/Nature Catalysis/6_2.png,vith,6_2.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_8.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_8.png,groundtruth,7_8.txt,train
Science Translational Medicine,17_779,Which of the following options best describe the cover story?,"ONLINE COVER Inflammation Identification. The cover image depicts different subtypes of T-lineage acute lymphoblastic leukemia (ALL) represented by different cells with the tile colors representing either an inflammatory or conventional phenotype. Although some patients with T-lineage ALL respond well to standard chemotherapy, others either do not respond at all or relapse after an initial response. To better stratify patients and understand disease heterogeneity, Gower et al. performed multiomics analysis on T-lineage ALL patient samples. The authors identified an inflammatory subtype of T lineage-ALL that was associated with poorer outcomes and insensitivity to dexamethasone. However, this subtype exhibited unique sensitivity to the clinically-approved BCL-2 inhibitor, venetoclax. The authors used this information to develop an inflammatory gene score that could be used to stratify patients and personalize treatments. Credit: SciStories",C,MAC_Bench/Science/Cover/Science Translational Medicine/13_610.png,MAC_Bench/Science/Cover/Science Translational Medicine/13_610.png,vith,13_610.txt,MAC_Bench/Science/Cover/Science Translational Medicine/3_108.png,MAC_Bench/Science/Cover/Science Translational Medicine/3_108.png,vitg,3_108.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_779.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_779.png,groundtruth,17_779.txt,MAC_Bench/Science/Cover/Science Translational Medicine/2_50.png,MAC_Bench/Science/Cover/Science Translational Medicine/2_50.png,clip,2_50.txt,train
Crystal Growth & Design,2025_3,Which of the following options best describe the cover story?,The pyrene-appended Fe(III) complex detects L-arginine compared to other amino acids via TURN-ON fluorescence through the Fe(III)/Fe(II) redox process. This graphic was created using Freepik’s AI Tool.,B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,ave_2,2019_11.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2003_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2003_1.png,vitg,2003_1.txt,train
Trends in Genetics,40_3,Which of the following options best describe the cover story?,"For decades, the field of evolutionary developmental biology (Evo-Devo)
has connected mechanisms driving variation in embryonic development with the
evolution of biodiversity. In this issue, Leslie Babonis argues that extending the
Evo-Devo
framework to single cells using new technologies makes it possible to understand the
origin and diversification of cells. Image credit: mikroman6/Getty Images.",A,MAC_Bench/Cell/Cover/Trends in Genetics/40_3.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_3.png,groundtruth,40_3.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_1.png,vitg,40_1.txt,MAC_Bench/Cell/Cover/Trends in Genetics/32_6.png,MAC_Bench/Cell/Cover/Trends in Genetics/32_6.png,clip,32_6.txt,MAC_Bench/Cell/Cover/Trends in Genetics/33_7.png,MAC_Bench/Cell/Cover/Trends in Genetics/33_7.png,vith,33_7.txt,test
Nature Reviews Nephrology,20_12,Which of the following options best describe the cover story?,"A spotlight on sex differences, inspired by this Focus issue.
Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_12.png,groundtruth,20_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_9.png,vitg,20_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_7.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_7.png,vith,18_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_4.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_4.png,clip,19_4.txt,train
ACS Synthetic Biology,2025_2,Which of the following options best describe the cover story?,"The key economic indicators, namely, titer, rate, and yield (TRY) that, respectively, reflect the downstream processing, reactor size, and raw material costs, serve as useful ways to benchmark intensified fermentation processes. BioTRY provides a user-friendly interface for querying, browsing, and visualizing TRY records in microbial processes.",C,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2012_5.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2012_5.png,ave_2,2012_5.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_9.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_9.png,clip,2023_9.txt,train
Trends in Cancer,10_3,Which of the following options best describe the cover story?,"Bispecific antibodies (bsAbs) can target two different epitopes or
antigens and can be leveraged for therapeutic targeting in cancer. The bsAb structure
can be engineered to enable diverse mechanisms of action – from dual modulation
of signaling pathways or immune checkpoints, to T cell, NK, or innate immune
cell engagers. In this issue, Herrera et al. provide a comprehensive review of this
rapidly evolving field, detailing advances in preclinical and clinical developments,
as well as challenges ahead. The cover art depicts the complexities of the tumor
microenvironment as a cosmos, and the moment a bispecific T cell engager binds to
and activates tumor-infiltrating T cells to enable cancer cell killing. Design by
Lewis
Au. Illustration by Jessica Johnson.",C,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,vitg,3_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/3_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_1.png,ave_2,3_1.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_3.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_3.png,groundtruth,10_3.txt,MAC_Bench/Cell/Cover/Trends in Cancer/1_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/1_1.png,clip,1_1.txt,train
Nature Reviews Bioengineering,2_7,Which of the following options best describe the cover story?,"High-throughput microfluidic 3D cell culture systems can be designed with different biological complexity, cell sources and cell configurations to model aspects of human tissues and organs. Such microfluidic systems can thereby serve as non-clinical testing tools for drug development. See Jihoon Ko et al.
Cover design: Simon Bradbrook",C,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,clip,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,vitg,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_7.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_7.png,groundtruth,2_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_5.png,vith,1_5.txt,train
Nature Mental Health,2_5,Which of the following options best describe the cover story?,"Countries and culture — mental health in context
Our August issue cover highlights how crucial our connections with countries and culture are and how they can meaningfully shape our mental health. In a sense, they are influences imprinted on brains and minds. From ancient philosophers and theologians to modern mental health researchers, country and culture have long been considered forces that affect our development and self-expression, our interpretations of feelings, and when and how we seek support or treatment for mental health conditions.
Read more in our Editorial about the importance of cultural context of mental health
Image: Jorg Greuel / Getty Images Plus. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,groundtruth,2_5.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,vitg,2_3.txt,val
Trends in Cancer,10_9,Which of the following options best describe the cover story?,"In the evolving era of cancer immunotherapy, combination strategies
are becoming ever more effective in overcoming challenges associated with PD-1
monotherapy. In this issue, Hashimoto et al. discuss the potential of PD-1/IL-2
combination regimen in enhancing anti-cancer therapy efficacy through shaping the
differentiation trajectory of CD8 T cells, thereby impacting their exhaustion program.
The cover depicts an effector CD8 T cell (upper right), generated by PD-1 blockade
and
IL-2 therapy, effectively finding and killing malignant cells (lower left). The cover
image
was created by Mie Yoshimura.",A,MAC_Bench/Cell/Cover/Trends in Cancer/10_9.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_9.png,groundtruth,10_9.txt,MAC_Bench/Cell/Cover/Trends in Cancer/4_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_1.png,ave_0,4_1.txt,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,vitg,3_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/1_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/1_1.png,clip,1_1.txt,test
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,22_2,Which of the following options best describe the cover story?,"Diet and intestinal stem cells, inspired by the Review on p23
Cover design: Neil Smith",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,vitg,20_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_1.png,vith,22_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_10.png,clip,18_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_2.png,groundtruth,22_2.txt,train
Journal of the American Chemical Society,2024_39,Which of the following options best describe the cover story?,Measurement of single-molecule conductance has emerged as a promising tool to unravel complex chemistry at the nanoscale. Single-molecule conductance and Flicker noise analysis can be employed to probe chemical reactions at the single-molecule level,C,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_42.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_42.png,ave_0,2011_42.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_41.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_41.png,vitg,2011_41.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_39.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_39.png,groundtruth,2024_39.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_9.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_9.png,clip,2010_9.txt,train
Journal of Chemical Theory and Computation,2024_13,Which of the following options best describe the cover story?,"Inspired by the movie Interstellar, we illustrate the spatially resolved adsorption loading surface of carbon dioxide in a porous material as the projection of a five-dimensional space (x, y, z, T, p) with infinite cells.",B,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,vitg,2024_17.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_13.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_13.png,groundtruth,2024_13.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_20.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_20.png,vith,2023_20.txt,val
Nature Aging,4_1,Which of the following options best describe the cover story?,"Focus on reproductive aging
Reproductive aging is an important determinant of fertility span and overall health and wellbeing in older age. In this issue, Nature Aging presents a series of reviews and opinion pieces on recent advances and future directions in reproductive aging research. The cover image shows seasonally colored trees — a springtime tree in green, and autumn trees in brilliant yellow and red — that represent different stages of reproductive physiology in aging.
See Editorial
Image: Alex Whitworth. Cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/Nature Aging/1_9.png,MAC_Bench/Nature/Cover/Nature Aging/1_9.png,clip,1_9.txt,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,ave_2,1_4.txt,MAC_Bench/Nature/Cover/Nature Aging/5_1.png,MAC_Bench/Nature/Cover/Nature Aging/5_1.png,ave_3,5_1.txt,MAC_Bench/Nature/Cover/Nature Aging/4_1.png,MAC_Bench/Nature/Cover/Nature Aging/4_1.png,groundtruth,4_1.txt,train
Nature Reviews Nephrology,20_5,Which of the following options best describe the cover story?,"Post-translational modifications, inspired by the Review on p495.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,clip,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_4.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_4.png,vitg,18_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_6.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_6.png,vith,17_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_5.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_5.png,groundtruth,20_5.txt,train
Nature Nanotechnology,19_11,Which of the following options best describe the cover story?,"Electron correlations without a twist
The cover image presents resistance maps of rhombohedral pentalayer graphene as a function of magnetic field and charge density. These maps provide evidence for correlation-driven Chern insulator states in a natural graphitic material. No moiré reconstruction is required.
See Han et al.
Image: Tonghang Han, Massachusetts Institute of Technology. Cover design: Valentina Monaco",D,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/8_12.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/8_12.png,ave_2,8_12.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/6_9.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/6_9.png,vitg,6_9.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_11.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_11.png,groundtruth,19_11.txt,train
ACS Applied Polymer Materials,2024_10,Which of the following options best describe the cover story?,"A carbon-based heterogeneous photoinitiator composed of a graphite nitride carbon (g-C3N4) and borates was reported. By incorporating the electron transferring between the UV-excited g-C3N4 and borates, this system exhibits good photoinduced initiating ability and enables effective photopolymerization of acrylates.",A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_11.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_11.png,vitg,2023_11.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_20.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_20.png,ave_0,2024_20.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_24.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_24.png,clip,2024_24.txt,train
NATURE MEDICINE,30_11,Which of the following options best describe the cover story?,"Preventing HBV transmission
In this issue, Hou, Liu and colleagues present interim results from the SHIELD program, showing that a comprehensive intervention package is feasible and effective in reducing mother-to-child transmission of hepatitis B virus (HBV) in various health settings in China. The cover is inspired by the traditional Chinese art of paper cutting and depicts a mother protecting her baby from infection with HBV.
See Yin et al.
Image: Jinlin Hou, Southern Medical University. Cover design: Marina Spence",A,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_11.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_11.png,groundtruth,30_11.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_1.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_1.png,vitg,25_1.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/29_7.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/29_7.png,vith,29_7.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_10.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_10.png,clip,26_10.txt,train
Trends in Ecology & Evolution,39_7,Which of the following options best describe the cover story?,"Plants are modular organisms built by three key processes: growth,
branching, and duplication of branching systems. Plant architectural traits reflect
key
functional responses to abiotic and biotic conditions. On pages 524–536, Marilyne
Laurans and colleagues argue that plant architecture can offer a dynamic view of the
whole-plant phenotype and a framework for characterizing integrated plant phenotype
and structuring plant trait networks. The cover shows a developing shoot of wild cherry,
Prunus avium. Photo credit: Patrick Heuret.",A,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_7.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_7.png,groundtruth,39_7.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_12.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_12.png,clip,39_12.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/30_5.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/30_5.png,vitg,30_5.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/33_7.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/33_7.png,ave_3,33_7.txt,train
Nature Chemical Biology,20_6,Which of the following options best describe the cover story?,"Tuning Cas kinetics for one-pot testing
Tong et al. found that the cleavage kinetics of Cas effectors need to be precisely tuned to maximize their sensitivity in one-pot nucleic acid detection. The image exemplifies the synchronized interplay between substrate amplification and cleavage by Cas effectors.
See Tong et al.
Image: Xiaohan Tong, Wuhan University. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_3.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_3.png,clip,15_3.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_2.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_2.png,vitg,13_2.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,vith,17_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_6.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_6.png,groundtruth,20_6.txt,train
NATURE MEDICINE,30_8,Which of the following options best describe the cover story?,"Heatwave mortality
In this issue, Xi et al. use data from a cohort of Chinese adults 65 years of age and older to show that variables related to functional aging are more predictive of increased heat-related mortality risk than is age alone. The cover highlights both the rise in global temperatures, via the color transition, and the importance of identifying those populations most vulnerable to climate change in order to inform targeted adaptation strategies.
See Xi et al.
Image: Yan Dong, Lanxi Xiao, Qiong Wu and Xiuge Zhang, Tsinghua University; at-large designers, Xuezhen Jin and Dezun Ji. Cover design: Marina Corral Spence",A,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_8.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_8.png,groundtruth,30_8.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_11.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_11.png,ave_2,26_11.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_12.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_12.png,clip,26_12.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/29_2.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/29_2.png,ave_3,29_2.txt,train
Trends in Biotechnology,42_6,Which of the following options best describe the cover story?,"Miniaturized in vitro bone models, known as ""mini-bones,"" have emerged as
powerful tools for studying physiology, disease mechanisms, and regenerative processes
of
bone, and for designing new bone-related therapies. In pages 910–928 of this issue,
Fois
and colleagues discuss how the mini-bones require small amounts of cells and materials,
are compatible with high-throughput production and screening methods and high-content
imaging, and offer good bone mimicry. This image highlights the concept of mini-bones
that
are made from cellular and matrix-mimicking building blocks in a bottom-up manner.
Cover
image designed by Daniela Velasco Lozano.",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_6.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_6.png,groundtruth,42_6.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_2.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_2.png,vitg,42_2.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/31_13.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/31_13.png,vith,31_13.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/32_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/32_12.png,clip,32_12.txt,train
Trends in Cell Biology,34_3,Which of the following options best describe the cover story?,"The musicians of Bremen, by unifying their forces through teamwork,
were able to accomplish something that none of them could have done alone: they
performed a strange concert to counteract the attack of bandits. In this issue, Costanzo
et al. show that the same is true for CSA and CSB, which, by cooperating with other
proteins in a ubiquitination complex, can accomplish and orchestrate functions
pivotal for various molecular mechanisms, such as DNA repair, gene expression, and
cell division. Cover design by Elena Paccosi & Luca Proietti De Santis.",A,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_3.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_3.png,groundtruth,34_3.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/24_6.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/24_6.png,vith,24_6.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/33_7.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/33_7.png,clip,33_7.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_14.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_14.png,vitg,27_14.txt,train
ACS Sustainable Chemistry & Engineering,2025_3,Which of the following options best describe the cover story?,Self-assembly of cellulose nanocrystals (CNCs) synthesized from rice straw yields transparent films with distinct structural colors. Amine modification of CNCs significantly improves the electron mobility and current–voltage characteristics. The transreflective property and photoresponsivity of,C,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_3.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_3.png,vith,2015_3.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_47.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_47.png,vitg,2021_47.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_3.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_7.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_7.png,clip,2015_7.txt,train
ACS Applied Bio Materials,2024_4,Which of the following options best describe the cover story?,"Green electricity is harvested from split black gram based triboelectric nanogenerators, powering autonomous lighting systems and portable electronics. Split black gram's abundance, cost-effectiveness, and eco-friendly properties make it an optimal choice for sustainable energy production, addressing environmental concerns associated with conventional TENG fabrication using synthetic materials. Cover is generated by an AI drawing tool",C,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_9.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_9.png,clip,2020_9.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_9.png,ave_3,2023_9.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_4.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_10.png,vith,2024_10.txt,train
Trends in Ecology & Evolution,40_2,Which of the following options best describe the cover story?,"Ethanol is present in many wild fruits, saps, and nectars. Moderate
ethanol intake is associated with nutritional, medicinal, and cognitive benefits,
but many
of these remain understudied for non-human species in natural contexts. On pages
67–79 Anna Bowland and colleagues discuss explanations for ethanol consumption
that span both nutritional and non-nutritional reasons and explore potential medicinal
value or cognitive effects. The cover image shows an adult female chimpanzee Pan
   troglodytes verus selecting and feeding on the ripe fruits of Ficus umbellata at Bossou,
Republic of Guinea. Photo credit: Cyril Ruoso.",C,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/40_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/40_1.png,clip,40_1.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_5.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_5.png,vith,34_5.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/40_2.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/40_2.png,groundtruth,40_2.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/33_6.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/33_6.png,vitg,33_6.txt,test
Cell Reports Methods,4_3,Which of the following options best describe the cover story?,"On the cover: In this issue, Quarles et al. present a method for high-throughput cryosectioning of hundreds of C. elegans in a single block, enabling improved access to antigens for immunostaining. As shown
in the cover image, they use this method to establish C. elegans as a multicellular model for studying the function of inorganic polyphosphate (depicted
in green). Image courtesy of Ellen Quarles.",B,MAC_Bench/Cell/Cover/Cell Reports Methods/3_2.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_2.png,ave_1,3_2.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_3.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_3.png,groundtruth,4_3.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_8.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_8.png,vith,2_8.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/1_6.png,MAC_Bench/Cell/Cover/Cell Reports Methods/1_6.png,clip,1_6.txt,val
Trends in Chemistry,7_2,Which of the following options best describe the cover story?,"Polyoxovanadates (POVs) are a versatile class of metal-oxido clusters
with excellent solution, redox and thermal stability, and are particularly noted for
binding
to various peptide and protein targets with various therapeutic outcomes. In their
Forum article in this issue, Merlino and co-workers discuss recent data on the structural
features and binding mechanisms of POVs with proteins, to help better elucidate
structure-property-function correlation. These studies can aid the development of
new
POVs, help to better understand their biological action, suggest new uses for known
structures and break into wider fields like biohybrid materials and energy process
engineering.
Cover image credit: Prof. Antonello Merlino",B,MAC_Bench/Cell/Cover/Trends in Chemistry/2_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/2_7.png,vith,2_7.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/7_2.png,MAC_Bench/Cell/Cover/Trends in Chemistry/7_2.png,groundtruth,7_2.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,vitg,5_9.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/7_1.png,MAC_Bench/Cell/Cover/Trends in Chemistry/7_1.png,clip,7_1.txt,val
Joule,8_2,Which of the following options best describe the cover story?,"On the cover: The rising global population is driving increased demand for food production
while farmers around the world confront unprecedented challenges due to changing climate
conditions. The cover image showcases a prototype electro-agriculture system, which
produces food using CO2 as the raw material. As presented by Crandall et al., this approach combines CO2 electrolysis with biological systems to boost food production efficiency. By utilizing
acetate generated from CO2 through renewable electricity, electro-agriculture enables the heterotrophic growth
of crops, bypassing the efficiency constraints of photosynthesis. Artist/image source:
Feng Jiao (Washington University in St. Louis in the United States).",B,MAC_Bench/Cell/Cover/Joule/4_2.png,MAC_Bench/Cell/Cover/Joule/4_2.png,clip,4_2.txt,MAC_Bench/Cell/Cover/Joule/8_2.png,MAC_Bench/Cell/Cover/Joule/8_2.png,groundtruth,8_2.txt,MAC_Bench/Cell/Cover/Joule/6_11.png,MAC_Bench/Cell/Cover/Joule/6_11.png,vitg,6_11.txt,MAC_Bench/Cell/Cover/Joule/8_6.png,MAC_Bench/Cell/Cover/Joule/8_6.png,vith,8_6.txt,train
Trends in Endocrinology & Metabolism,35_9,Which of the following options best describe the cover story?,"Climate change is causing record-breaking temperatures across
the globe. As the projected death toll caused by heat increases, it is important to
understand its effects on metabolic health and find short- and long-term adaptation
strategies. This month, Pallubinsky and colleagues mark Earth Day (April 22nd)
discussing the double-edged sword of heat on human health, highlighting its impact
on human physiology and discussing how to improve heat resilience. Our cover image
features Record Breaking Heat from the Environmental Graphiti series “The Art of
Climate Change—Why is our climate changing?”. The artwork, based on data from the
World Meteorological Organization, shows the global mean temperature differences
compared to the 1850-1900 average. The peak at the top right shows 2023, the
warmest year in the 174-year observational record. Cover by Alisa Singer (http://www.environmentalgraphiti.org/),
courtesy of the artist.",C,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_4.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_4.png,vith,26_4.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,ave_2,27_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_9.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_9.png,groundtruth,35_9.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_10.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_10.png,clip,25_10.txt,train
Journal of Proteome Research,2024_6,Which of the following options best describe the cover story?,"A California sea lion swimming in the surf at Pacifica, California. Domoic acid toxicosis is a major affliction for sea lions in California. Photo credit: Pádraig Duignan.",B,MAC_Bench/ACS/Cover/Journal of Proteome Research/2018_10.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2018_10.png,vith,2018_10.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_6.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2011_8.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2011_8.png,vitg,2011_8.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2021_9.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2021_9.png,clip,2021_9.txt,train
Nature Metabolism,6_7,Which of the following options best describe the cover story?,"Time to exercise
Exposing mice to physical activity during their early active phase favours bone growth. The image depicts a rodent on a running wheel, which also alludes to the importance of the timing of exercise in achieving metabolic improvements.
See Yu, Tang et al.
Image: Will & Deni McIntyre/Getty Images. Cover design: Thomas Phillips",C,MAC_Bench/Nature/Cover/Nature Metabolism/1_6.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Metabolism/2_4.png,MAC_Bench/Nature/Cover/Nature Metabolism/2_4.png,clip,2_4.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_7.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_7.png,groundtruth,6_7.txt,MAC_Bench/Nature/Cover/Nature Metabolism/1_11.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_11.png,vith,1_11.txt,test
Nature Geoscience,17_1,Which of the following options best describe the cover story?,"The future of deep ocean drilling
The recent decommissioning of the JOIDES Resolution vessel run by the International Ocean Drilling Program presents a challenge for research reliant on deep-ocean drilling. The image shows the ship’s drilling derrick behind pipe racks involved in the collection of deep-sea sediment cores during International Ocean Discovery Program Expedition 403 to the Fram Strait during the summer of 2024.
See Q&A.
Image: Thomas Ronge, IODP JRSO. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Geoscience/6_11.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_11.png,clip,6_11.txt,MAC_Bench/Nature/Cover/Nature Geoscience/9_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/9_1.png,ave_3,9_1.txt,MAC_Bench/Nature/Cover/Nature Geoscience/9_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/9_7.png,vith,9_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_1.png,groundtruth,17_1.txt,train
Crystal Growth & Design,2024_6,Which of the following options best describe the cover story?,Expanding the sparsely populated library of lanthanide MOF crystal structures is building a knowledge treasure trove that will ultimately inform material design and application. This graphic was generated with help from Google Gemini.,A,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_6.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_4.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_4.png,clip,2025_4.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_17.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_17.png,vitg,2024_17.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2015_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2015_2.png,vith,2015_2.txt,train
Nature Reviews Electrical Engineering,1_2,Which of the following options best describe the cover story?,"In alignment with UN Sustainable Development Goal 9, it is crucial to develop advanced spintronic technologies for low-power, beyond-CMOS devices. In this Focus Issue, we discuss the challenges and potential solutions in spintronics for neuromorphic computing, STT-MRAM, and logic applications. We also highlight the importance of integrating spintronic devices with existing silicon platforms and fostering collaboration between academia and industry. Additionally, we encourage the exploration of emerging materials and devices for low-power spintronics, such as two-dimensional magnets. See the Editorial
Image: Zulfidin Khodzhaev, The University of Texas at Austin Cover design: Sam Whitham",D,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,clip,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,ave_3,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_2.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_2.png,groundtruth,1_2.txt,train
BDJ,237_6,Which of the following options best describe the cover story?,"In this issue
This issue features articles on oral syphilis, removable partial dentures, and edentulous patients.

Cover image: From 2013. The image on the front of this edition is a celebration of our Themed Issues. These began in 2013 and to date number 22, with more planned for 2025 and beyond.
©Tim Marrs",C,MAC_Bench/Nature/Cover/BDJ/233_2.png,MAC_Bench/Nature/Cover/BDJ/233_2.png,vitg,233_2.txt,MAC_Bench/Nature/Cover/BDJ/237_1.png,MAC_Bench/Nature/Cover/BDJ/237_1.png,vith,237_1.txt,MAC_Bench/Nature/Cover/BDJ/237_6.png,MAC_Bench/Nature/Cover/BDJ/237_6.png,groundtruth,237_6.txt,MAC_Bench/Nature/Cover/BDJ/228_11.png,MAC_Bench/Nature/Cover/BDJ/228_11.png,clip,228_11.txt,train
NATURE REVIEWS IMMUNOLOGY,24_11,Which of the following options best describe the cover story?,"Thymic selection, inspired by the Review on p103.
Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_5.png,vitg,23_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/17_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/17_8.png,vith,17_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_11.png,groundtruth,24_11.txt,train
Nature Protocols,19_8,Which of the following options best describe the cover story?,"Illuminating digital cells on a microscopic stage.
A detailed digital reconstruction of an animal cell receiving light cast from afar. This represents the transformation of cells from microscopy images into a form suitable for accurate optical modeling of electromagnetic wave propagation.
Image: John Ball, National Eye Institute, National Institutes of Health. Adapted from Lauri Purhonen, Sketchfab, under a Creative Commons license CC BY 4.0. Cover design: S. Whitham.",D,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,clip,19_9.txt,MAC_Bench/Nature/Cover/Nature Protocols/18_4.png,MAC_Bench/Nature/Cover/Nature Protocols/18_4.png,vith,18_4.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_3.png,MAC_Bench/Nature/Cover/Nature Protocols/19_3.png,vitg,19_3.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_8.png,MAC_Bench/Nature/Cover/Nature Protocols/19_8.png,groundtruth,19_8.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_10,Which of the following options best describe the cover story?,"‘Making synthetic cells’, inspired by the Comment on p157 and Viewpoint on p162.
Cover design: Vicky Summersby.",B,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_10.png,vitg,23_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_10.png,groundtruth,25_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/16_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/16_1.png,vith,16_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,clip,24_6.txt,val
Nature Nanotechnology,19_1,Which of the following options best describe the cover story?,"Complete photonic bandgap in the visible
The image on the cover shows a 3D-printed sculpture composed of nanoscale gyroid crystals in titania that exhibit optical chirality under visible light.
See Yang et al.
Image: Wang Zhang, Joel K. W. Yang, Singapore University of Technology and Design. Cover design: Vanitha Selvarajan",C,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/9_11.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/9_11.png,vith,9_11.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_1.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_1.png,groundtruth,19_1.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/10_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/10_8.png,vitg,10_8.txt,train
Nature Synthesis,3_5,Which of the following options best describe the cover story?,"Enzymatic C(sp 3)–F bond formation
Enantioselective C(sp 3)–F bond formation is reported using an engineered non-haem iron enzyme. The process proceeds through a radical fluorine atom transfer pathway, which converts N-fluoroamides into chiral benzyl fluorides.
See Zhao et al.
Image: Yunfang Yang, Zhejiang University of Technology. Cover design: Emily Paul",A,MAC_Bench/Nature/Cover/Nature Synthesis/3_5.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_5.png,groundtruth,3_5.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_10.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_1.png,vitg,1_1.txt,val
Science Immunology,9_98,Which of the following options best describe the cover story?,"ONLINE COVER Specialized Macrophages Repair the Lung After Damage. Airborne pathogens and pollutants can cause long-lasting lung damage, but how lung myeloid cells contribute to postinjury repair is not fully understood. Ruscitti et al. identified a population of Ly6G+ macrophages that emerges during the early recovery phase after influenza virus–triggered lung injury in mice. These Ly6G+ macrophages were short-lived, monocyte-derived cells that populated alveoli near the site of damage and promoted epithelial repair. This month’s cover illustration depicts damaged lung alveoli as burning buildings, from which falling debris (representing signals such as GM-CSF and type 2 cytokines) promotes monocyte differentiation into reparative Ly6G+ macrophages. Credit: Adeline Deward/Illumine",B,MAC_Bench/Science/Cover/Science Immunology/6_56.png,MAC_Bench/Science/Cover/Science Immunology/6_56.png,vith,6_56.txt,MAC_Bench/Science/Cover/Science Immunology/9_98.png,MAC_Bench/Science/Cover/Science Immunology/9_98.png,groundtruth,9_98.txt,MAC_Bench/Science/Cover/Science Immunology/2_18.png,MAC_Bench/Science/Cover/Science Immunology/2_18.png,clip,2_18.txt,MAC_Bench/Science/Cover/Science Immunology/6_58.png,MAC_Bench/Science/Cover/Science Immunology/6_58.png,vitg,6_58.txt,train
Cell Systems,16_2,Which of the following options best describe the cover story?,"On the cover: Heatmap of temporal activity of ERK, measured using the modified ERK
kinase translocation reporter (KTR) and read out as cytoplasmic:nuclear ratio in thousands
of single A375 cells, before and after treatment with 10 nM Trametinib indicated by
the black line. In this issue of Cell Systems, Hoffman et al. find that ERK and p38 KTRs can be partly phosphorylated by CDK2, a phenomenon unmasked
under MAPK pathway inhibition. The authors show that the modified FRET-based sensor,
EKAREN5, does not show this crosstalk and that, by co-expressing the ERK or p38 KTR
with the CDK2 sensor, contributions of CDK2 activity on the KTR signals can be removed.
Image credit: the authors.",D,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,vith,11_2.txt,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,clip,1_2.txt,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,vitg,7_2.txt,MAC_Bench/Cell/Cover/Cell Systems/16_2.png,MAC_Bench/Cell/Cover/Cell Systems/16_2.png,groundtruth,16_2.txt,test
NATURE REVIEWS MICROBIOLOGY,22_7,Which of the following options best describe the cover story?,"A path to HIV elimination and cure, inspired by the Review on p328.
Cover design: Philip Patenall.",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,vitg,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_6.png,clip,22_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_11.png,vith,21_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_7.png,groundtruth,22_7.txt,train
Lab Animal,53_2,Which of the following options best describe the cover story?,"A new cardiovascular-kidney-metabolic syndrome model
Cardiovascular-kidney-metabolic (CKM) syndrome is a complex disorder made up of cardiovascular disease, kidney disease, obesity and Type 2 diabetes. In a new Article, Carvalho et al. describe a novel mouse model of CKM syndrome induced by unilateral nephrectomy and a Western diet rich in carbohydrates, fat and salt, which could be used to study human condition and identify therapies.
See Carvalho et al
Cover image: Marina Spence. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/Lab Animal/52_2.png,MAC_Bench/Nature/Cover/Lab Animal/52_2.png,clip,52_2.txt,MAC_Bench/Nature/Cover/Lab Animal/53_2.png,MAC_Bench/Nature/Cover/Lab Animal/53_2.png,groundtruth,53_2.txt,MAC_Bench/Nature/Cover/Lab Animal/52_4.png,MAC_Bench/Nature/Cover/Lab Animal/52_4.png,ave_2,52_4.txt,MAC_Bench/Nature/Cover/Lab Animal/50_4.png,MAC_Bench/Nature/Cover/Lab Animal/50_4.png,ave_3,50_4.txt,train
Nature Reviews Clinical Oncology,21_4,Which of the following options best describe the cover story?,"Understanding chromosomal instability in cancer, inspired by the Review on p645.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,vitg,19_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_2.png,clip,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_2.png,vith,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_4.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_4.png,groundtruth,21_4.txt,train
NATURE METHODS,22_1,Which of the following options best describe the cover story?,"Aligning single cell trajectories
Conceptual visualization of aligning cells from two different datasets in time and space. Computational alignment is helping the Human Cell Atlas community create reference maps of the body to understand health and disease.
See Article
Image: Dinithi Sumanaweera, University of Cambridge | Su Min Suh, SciStories LLC. Cover design: Thomas Phillips",D,MAC_Bench/Nature/Cover/NATURE METHODS/11_4.png,MAC_Bench/Nature/Cover/NATURE METHODS/11_4.png,vith,11_4.txt,MAC_Bench/Nature/Cover/NATURE METHODS/10_11.png,MAC_Bench/Nature/Cover/NATURE METHODS/10_11.png,vitg,10_11.txt,MAC_Bench/Nature/Cover/NATURE METHODS/13_11.png,MAC_Bench/Nature/Cover/NATURE METHODS/13_11.png,clip,13_11.txt,MAC_Bench/Nature/Cover/NATURE METHODS/22_1.png,MAC_Bench/Nature/Cover/NATURE METHODS/22_1.png,groundtruth,22_1.txt,val
Current Biology,34_23,Which of the following options best describe the cover story?,"On the cover: Bundles of in vitro reconstituted, oriented actin filaments (in magenta) formed in the presence of an
abundant microtubule polymerase CKAP5 (also known as chTOG, or XMAP215 from X. laevis; in cyan). In this issue, Sabo et al. describe novel functions of CKAP5 using a combination of in vitro reconstitution and neuronal explant experiments. The authors show that CKAP5 autonomously
bundles actin filaments (seen here on the cover), crosslinks actin filaments to microtubules
regardless of their polarity, and enables the formation of persistent actin bundles
templated by dynamically unstable microtubules. Cover image by Jan Sabo.",C,MAC_Bench/Cell/Cover/Current Biology/31_12.png,MAC_Bench/Cell/Cover/Current Biology/31_12.png,vitg,31_12.txt,MAC_Bench/Cell/Cover/Current Biology/25_23.png,MAC_Bench/Cell/Cover/Current Biology/25_23.png,clip,25_23.txt,MAC_Bench/Cell/Cover/Current Biology/34_23.png,MAC_Bench/Cell/Cover/Current Biology/34_23.png,groundtruth,34_23.txt,MAC_Bench/Cell/Cover/Current Biology/34_7.png,MAC_Bench/Cell/Cover/Current Biology/34_7.png,vith,34_7.txt,train
BDJ In Practice,37_3,Which of the following options best describe the cover story?,"In this issue...
Dental academia is something every qualified dentist has experienced. And just like the wider profession, it is suffering. October's cover feature asks what is the current state of dental academia
Cover illustration by Tim Marrs",A,MAC_Bench/Nature/Cover/BDJ In Practice/37_3.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_3.png,groundtruth,37_3.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,vitg,35_8.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,clip,36_1.txt,MAC_Bench/Nature/Cover/BDJ In Practice/34_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/34_2.png,vith,34_2.txt,test
Immunity,57_12,Which of the following options best describe the cover story?,"On the cover: As a component of personalized medicine, precision nutrition offers
the opportunity to transform our understanding and treatment of immune-mediated chronic
inflammatory diseases, metabolic disorders, and cancer. Tailoring specific dietary
interventions to an individual's unique genetic makeup, microbiota composition, metabolism,
health status, and lifestyle has the potential to alter management of human health
and disease. In this issue, Arifuzzaman et al. review how diets rich in fiber, sugar, or fat influence the composition of the microbiota
and microbiota-derived metabolites and their impact on the balance of proinflammatory,
immune-regulatory, and tissue-protective innate and adaptive immune responses. The
authors highlight the impact of diet-microbiota communications on immunity to infection,
chronic inflammation, and cancer and outline important challenges in mechanistic understanding
that currently limit progress toward the goal of precision nutrition as a strategic
component of therapeutic interventions. Image by Mohammad Arifuzzaman and David Artis,
created with Biorender.com.",B,MAC_Bench/Cell/Cover/Immunity/41_3.png,MAC_Bench/Cell/Cover/Immunity/41_3.png,vith,41_3.txt,MAC_Bench/Cell/Cover/Immunity/57_12.png,MAC_Bench/Cell/Cover/Immunity/57_12.png,groundtruth,57_12.txt,MAC_Bench/Cell/Cover/Immunity/42_4.png,MAC_Bench/Cell/Cover/Immunity/42_4.png,vitg,42_4.txt,MAC_Bench/Cell/Cover/Immunity/39_5.png,MAC_Bench/Cell/Cover/Immunity/39_5.png,clip,39_5.txt,train
Nature Cell Biology,26_12,Which of the following options best describe the cover story?,"Celebrating 25 years of cell biology
Celebrating 25 years of cell biology.
See Focus
Image: CHRISTOPH BURGSTEDT/SCIENCE PHOTO LIBRARY/Getty. Cover Design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Cell Biology/21_12.png,MAC_Bench/Nature/Cover/Nature Cell Biology/21_12.png,clip,21_12.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_12.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_12.png,groundtruth,26_12.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/11_1.png,MAC_Bench/Nature/Cover/Nature Cell Biology/11_1.png,ave_2,11_1.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/19_9.png,MAC_Bench/Nature/Cover/Nature Cell Biology/19_9.png,ave_3,19_9.txt,train
Trends in Microbiology,33_2,Which of the following options best describe the cover story?,"In this issue, Gerber-Tichet et al. provide an update on the expanding
role of the function of Toll-like receptor 4 (TLR4), a germline-encoded pattern
recognition receptor (PRR). The archetypal role TLR4 is the detection bacterial wall
components, including lipopoly- and lipo-oligo-saccharides (LPS and LOS). The cover
shows antigen-presenting cells (APCs), which are the sentinels of the immune system,
containing cell surface dimers of TLR4 dimers, one of the ten members of the TLR
family. However, TLR4 is not a one trick pony – it can also generate anti-viral innate
immune responses via TRIF-related adaptor molecule-associated signalling directly
or
indirectly (e.g., Ebola or adenovirus via an alpha-defensin bridge, respectively).
Image courtesy: Conception and design by Elina Gerber-Tichet and EJ Kremer.
BioRender® was used to generate an initial template.",A,MAC_Bench/Cell/Cover/Trends in Microbiology/33_2.png,MAC_Bench/Cell/Cover/Trends in Microbiology/33_2.png,groundtruth,33_2.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/27_6.png,MAC_Bench/Cell/Cover/Trends in Microbiology/27_6.png,vitg,27_6.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/24_12.png,MAC_Bench/Cell/Cover/Trends in Microbiology/24_12.png,vith,24_12.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/33_1.png,MAC_Bench/Cell/Cover/Trends in Microbiology/33_1.png,clip,33_1.txt,train
Matter,8_2,Which of the following options best describe the cover story?,"On the cover: This cover features conductive thin films designed to protect drones
in extreme weather conditions. In this issue, Wu and colleagues explore material engineering through the integration of experiments and theories.
By combining layer-by-layer assembly and graph theory, electrical properties are modeled
based on the complex structures of the nanoscale networks. Image courtesy of the authors.",D,MAC_Bench/Cell/Cover/Matter/2_1.png,MAC_Bench/Cell/Cover/Matter/2_1.png,vitg,2_1.txt,MAC_Bench/Cell/Cover/Matter/2_6.png,MAC_Bench/Cell/Cover/Matter/2_6.png,ave_1,2_6.txt,MAC_Bench/Cell/Cover/Matter/8_1.png,MAC_Bench/Cell/Cover/Matter/8_1.png,clip,8_1.txt,MAC_Bench/Cell/Cover/Matter/8_2.png,MAC_Bench/Cell/Cover/Matter/8_2.png,groundtruth,8_2.txt,test
ACS Macro Letters,2025_2,Which of the following options best describe the cover story?,Bicontinuously structured polymeric nanoparticles through direct self-assembly in aqueous media from doxorubicin containing redox and pH-labile prodrug that promote loading of both hydrophobic and hydrophilic cargoes as promising cancer drug delivery systems.,B,MAC_Bench/ACS/Cover/ACS Macro Letters/2019_6.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2019_6.png,clip,2019_6.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2019_11.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2019_11.png,ave_1,2019_11.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_7.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_7.png,vitg,2020_7.txt,test
Chemical & Biomedical ImagingOpen Access,2024_8,Which of the following options best describe the cover story?,"The cover depicts the tip-enhanced Raman spectroscopy characterization of thin-film FeO/Au(100). A laser is confined to the tip-sample junction with the silver tip extremely close to the FeO, which induces the enhanced Raman signal. This research unveils a gateway to the chemical probing of thin-film oxide materials at the nanoscale.  View the article.",C,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_4.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_4.png,ave_1,2023_4.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_8.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_8.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_1.png,ave_2,2025_1.txt,test
Cell Metabolism,36_12,Which of the following options best describe the cover story?,"On the cover: In the human body (tree), apoptotic cells and vesicles (fallen blossoms)
are not the waste, which can release hydrogen sulfide (H2S). The H2S from apoptotic cells and vesicles can re-nourish our body, maintaining immune homeostasis.
Ou et al. reveal the unknown role of apoptosis in immune homeostasis. As the old saying goes,
“The fallen petals, in return, will transform into soil to nourish the flower in spring.”
落红不是无情物, 化作春泥更护花 (in Chinese).",B,MAC_Bench/Cell/Cover/Cell Metabolism/36_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_3.png,vitg,36_3.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_12.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_12.png,groundtruth,36_12.txt,MAC_Bench/Cell/Cover/Cell Metabolism/18_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/18_5.png,ave_1,18_5.txt,MAC_Bench/Cell/Cover/Cell Metabolism/34_10.png,MAC_Bench/Cell/Cover/Cell Metabolism/34_10.png,clip,34_10.txt,train
Nano Letters,2025_3,Which of the following options best describe the cover story?,An evanescent near field (golden particles) beneath the apex of a metallic tip launches a surface plasmon polariton wave (golden surface wave) on an atomically thin graphene layer (hexagonal ball and stick model).,C,MAC_Bench/ACS/Cover/Nano Letters/2024_17.png,MAC_Bench/ACS/Cover/Nano Letters/2024_17.png,clip,2024_17.txt,MAC_Bench/ACS/Cover/Nano Letters/2024_4.png,MAC_Bench/ACS/Cover/Nano Letters/2024_4.png,ave_1,2024_4.txt,MAC_Bench/ACS/Cover/Nano Letters/2025_3.png,MAC_Bench/ACS/Cover/Nano Letters/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Nano Letters/2024_37.png,MAC_Bench/ACS/Cover/Nano Letters/2024_37.png,ave_2,2024_37.txt,train
Trends in Plant Science,29_3,Which of the following options best describe the cover story?,"Sucrose, derived from photosynthesis, serves as the primary energy
source for plants. It is produced in the leaves and transported to the roots via the
phloem, playing a crucial role in providing energy. Environmental conditions can affect
photosynthesis, influencing the sucrose budget available for roots. Plants can adapt
their root systems to optimize resource uptake from the soil and ensure the plant's
adaptability to diverse environmental conditions. Tom Beeckman and colleagues
review emerging research indicating that SnRK1, T6P, and TOR collectively serve as
fundamental regulators of root development together forming a signaling module to
interpret the nutritional status of the plant and translate this to growth adjustments
in the
below ground parts. Image credit: Elissa Steil.",D,MAC_Bench/Cell/Cover/Trends in Plant Science/25_6.png,MAC_Bench/Cell/Cover/Trends in Plant Science/25_6.png,vitg,25_6.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/24_7.png,MAC_Bench/Cell/Cover/Trends in Plant Science/24_7.png,vith,24_7.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/26_13.png,MAC_Bench/Cell/Cover/Trends in Plant Science/26_13.png,clip,26_13.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_3.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_3.png,groundtruth,29_3.txt,train
Nature Synthesis,3_4,Which of the following options best describe the cover story?,"Room-temperature m-benzyne
The room temperature and atmospheric pressure synthesis of m-benzyne is reported. Benzyne is a highly reactive organic intermediate derived from benzene and while the properties of o- and p-benzyne isomers have been studied in detail, m-benzyne in the ground state has previously been experimentally difficult to access.
See Koyamada et al.
Image: Masanobu Uchiyama, University of Tokyo. Cover design: Emily Paul",A,MAC_Bench/Nature/Cover/Nature Synthesis/3_4.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_4.png,groundtruth,3_4.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_10.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_10.png,vitg,2_10.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_2.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_2.png,ave_2,2_2.txt,train
ACS Applied Nano Materials,2025_6,Which of the following options best describe the cover story?,"from 2-hydroxypropyl-β-cyclodextrin. The supramolecular system with iodine (Cdots-HPβCD/I2) exhibits iodine release and antimicrobial effects against pathogenic bacteria. Low cytotoxicity and effective interactions with human cells were demonstrated. The bioinspired Cdots-HPβCD, combining good optical properties and nanocarrier capability, is a promising candidate for multimodal therapy.",B,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_12.png,ave_3,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_6.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2022_11.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2022_11.png,vitg,2022_11.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2024_15.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2024_15.png,clip,2024_15.txt,train
Nature Reviews Bioengineering,2_9,Which of the following options best describe the cover story?,"Bioplastics are derived from renewable carbon sources and/or are degradable at their end-of-life stage, thereby providing a potential solution to plastics pollution. However, lengthy and expensive testing and certification processes, as well as greenwashing and public misconceptions currently hinder the widespread usage and adequate disposal of bioplastics. See Lam Tan Hao et al.
Cover design: Simon Bradbrook.",D,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,ave_3,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_3.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_3.png,ave_2,2_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_8.png,clip,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_9.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_9.png,groundtruth,2_9.txt,train
iScience,27_4,Which of the following options best describe the cover story?,"On the Cover: The cover image represents the profound connection between the brain
and the gut microbiome, central to the study by Novielli et al. on the personalized identification of autism-related bacteria using eXplainable Artificial
Intelligence (XAI). The left half of the image, depicting the brain with illuminated
neural circuits, symbolizes the application of advanced AI techniques. The right half,
showcasing the gut with various microorganisms, highlights the diversity of the microbiome
and its potential link to autism. This visual metaphor encapsulates our study's dual
focus: utilizing AI to identify specific gut bacteria associated with autism and enhancing
our understanding of the gut-brain axis in neurodevelopmental disorders. Image credit:
Sabina Tangaro.",C,MAC_Bench/Cell/Cover/iScience/27_8.png,MAC_Bench/Cell/Cover/iScience/27_8.png,vitg,27_8.txt,MAC_Bench/Cell/Cover/iScience/6_1.png,MAC_Bench/Cell/Cover/iScience/6_1.png,clip,6_1.txt,MAC_Bench/Cell/Cover/iScience/27_4.png,MAC_Bench/Cell/Cover/iScience/27_4.png,groundtruth,27_4.txt,MAC_Bench/Cell/Cover/iScience/24_12.png,MAC_Bench/Cell/Cover/iScience/24_12.png,ave_3,24_12.txt,test
ACS Central Science,2024_4,Which of the following options best describe the cover story?,Integration of explainable artificial intelligence (AI) with quantum tunneling technology enables the single-molecule identification of complex carbohydrate anomers and stereoisomers over a dynamic configuration space with accuracy as high as 100%.,B,MAC_Bench/ACS/Cover/ACS Central Science/2023_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_4.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_1.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_1.png,ave_1,2023_1.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_7.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_7.png,vitg,2024_7.txt,train
Trendsin Neurosciences,47_4,Which of the following options best describe the cover story?,"Synucleinopathies are characterized by neuronal loss accompanied by
α-synuclein accumulation in the brain. While research conventionally focused on brain
pathology, there is growing evidence for peripheral alterations in synucleinopathies,
including in erythrocytes, which are rich in α-synuclein. Erythrocyte-derived extracellular
vesicles, containing pathological α-synuclein species, can traverse the blood–brain
barrier under certain conditions, as well as the gastrointestinal tract, where α-synuclein
and gut microbiota interact extensively. In this issue of Trends in Neurosciences, Ying
Yang and colleagues explore the accumulating evidence of erythrocyte involvement in
synucleinopathies, as well as their potential in disease pathogenesis and diagnosis.
Image credits: Science Photo Library – SCIEPRO / Getty Images.",A,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_4.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_4.png,groundtruth,47_4.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/46_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/46_9.png,vitg,46_9.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/45_10.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/45_10.png,clip,45_10.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_13.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_13.png,vith,38_13.txt,train
Nature Reviews Psychology,4_1,Which of the following options best describe the cover story?,"In this Review, Cheryan et al. discuss four factors that might explain women’s underrepresentation in some STEM fields and interventions that might help reduce these disparities.
Cover design: David Johnston",B,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_6.png,vith,1_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/4_1.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/4_1.png,groundtruth,4_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_8.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_8.png,clip,3_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_4.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_4.png,vitg,3_4.txt,train
NATURE METHODS,21_8,Which of the following options best describe the cover story?,"Focus on methods for immunology
A scanning electron microscope image captures the dynamic interplay between a CD19-hexapod biomimetic antigen-presenting structure and an anti-CD19 CAR-T cell.
See Huang et al.
Image: Bozhi Tian, University of Chicago. Cover design: Thomas Phillips",B,MAC_Bench/Nature/Cover/NATURE METHODS/7_4.png,MAC_Bench/Nature/Cover/NATURE METHODS/7_4.png,vitg,7_4.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_8.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_8.png,groundtruth,21_8.txt,MAC_Bench/Nature/Cover/NATURE METHODS/18_8.png,MAC_Bench/Nature/Cover/NATURE METHODS/18_8.png,vith,18_8.txt,MAC_Bench/Nature/Cover/NATURE METHODS/11_2.png,MAC_Bench/Nature/Cover/NATURE METHODS/11_2.png,clip,11_2.txt,val
ACS Macro Letters,2024_5,Which of the following options best describe the cover story?,"The introduction of crown ether at the terminus marks a novel and effective strategy to not only elevate message readability, but also to increase the information storage capacity of digital polymers, leveraging a simple and classical property of crown ether since its discovery by a great chemist, Charles Pedersen, in 1967.",A,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_5.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2015_5.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2015_5.png,vitg,2015_5.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2022_3.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2022_3.png,vith,2022_3.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2019_12.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2019_12.png,clip,2019_12.txt,train
Nature Synthesis,3_3,Which of the following options best describe the cover story?,"Crystallization quality control
A flux-regulated crystallization method is introduced for controlling the linear growth rate of perovskites, leading to high-quality single crystals.
See Saidaminov et al.
Image: Yuki Haruta, University of Victoria. Cover design: Emily Paul",C,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,clip,3_1.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_5.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_5.png,ave_2,2_5.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_3.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_3.png,groundtruth,3_3.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,ave_1,2_6.txt,train
NATURE REVIEWS CANCER,24_5,Which of the following options best describe the cover story?,"The road less travelled, inspired by the Roadmap on p578.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,ave_2,25_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_5.png,groundtruth,24_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,ave_1,23_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_1.png,clip,23_1.txt,train
NATURE MATERIALS,23_2,Which of the following options best describe the cover story?,"Nuclear jamming during organ growth
Developing zebrafish retina and brain tissues undergo a nuclear jamming transition that induces crystalline-like cellular ordering, with the emergent tissue stiffness controlled by nuclear mechanics.
See Kim et al.
Image: Rana Amini and Otger Campàs, Cluster of Excellence Physics of Life, TU Dresden. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_2.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_2.png,groundtruth,23_2.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/16_1.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/16_1.png,vith,16_1.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_9.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_9.png,clip,19_9.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_7.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_7.png,vitg,23_7.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_8,Which of the following options best describe the cover story?,"‘Growing plant walls’, inspired by the Review on p340
Cover design: Vicky Summersby",C,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_2.png,vitg,21_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_3.png,ave_2,23_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_8.png,groundtruth,25_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_2.png,clip,25_2.txt,train
Cell Stem Cell,31_6,Which of the following options best describe the cover story?,"On the cover: In this issue, Shen et al. establish feasible methodologies that significantly improve the production and function
of human pluripotent stem cell-derived CAR-macrophages (hPSC-CAR-Ms) for cancer immunotherapy.
In the image, the macrophage (in yellow) represents a repolarized activated hPSC-CAR-M.
The hPSC-CAR-M waves a knife, fork, and spoon to kill and eat tumor cells (in red).
Moreover, the hPSC-CAR-M has recruited T cells (in blue) to synergistically destroy
the tumor cells. Cover art by Jun Shen and Wenxi Ye.",A,MAC_Bench/Cell/Cover/Cell Stem Cell/31_6.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_6.png,groundtruth,31_6.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/10_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/10_2.png,clip,10_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/22_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/22_2.png,vith,22_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/28_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/28_4.png,ave_1,28_4.txt,test
Nature Reviews Endocrinology,20_5,Which of the following options best describe the cover story?,"Targeting the incretin system in obesity and type 2 diabetes mellitus, inspired by the Review on p447.
Cover design: Jennie Vallis",A,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_5.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_5.png,groundtruth,20_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,vith,18_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_7.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_7.png,vitg,20_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/14_10.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/14_10.png,clip,14_10.txt,train
Biophysical Journal,124_5,Which of the following options best describe the cover story?,"Cover picture: The image shows a synthetic cell-cell communication pathway in action within developing
Drosophila wing tissue. Blue marks the signal protein on the surface of a population of signal-sending
cells, and where they meet the red receptor protein on the surface of a population
of signal-receiving cells, they induce the expression of the green fluorescent protein
transcriptional output. DOI: 10.1016/j.bpj.2024.11.007.",B,MAC_Bench/Cell/Cover/Biophysical Journal/111_7.png,MAC_Bench/Cell/Cover/Biophysical Journal/111_7.png,vith,111_7.txt,MAC_Bench/Cell/Cover/Biophysical Journal/124_5.png,MAC_Bench/Cell/Cover/Biophysical Journal/124_5.png,groundtruth,124_5.txt,MAC_Bench/Cell/Cover/Biophysical Journal/119_7.png,MAC_Bench/Cell/Cover/Biophysical Journal/119_7.png,clip,119_7.txt,MAC_Bench/Cell/Cover/Biophysical Journal/112_4.png,MAC_Bench/Cell/Cover/Biophysical Journal/112_4.png,vitg,112_4.txt,train
Cell Host&Microbe,32_7,Which of the following options best describe the cover story?,"On the cover: The cover depicts the direct communication between Enterococcus bacteria (purple) and intestine stem cells (ISCs) (blue) in inflammatory bowel disease.
In this issue of Cell Host & Microbe, Li et al. demonstrate that a metabolite derived from Enterococcus bacteria hijacks an adrenergic receptor in ISCs, directly suppressing ISC proliferation
and epithelial regeneration, thereby exacerbating colitis. This special issue of Cell Host & Microbe also presents a microbial survival guide. Microbes face harsh environments that they
must adapt to in order to survive, grow/proliferate, and spread. This collection (or
guide) consists of a series of review and primary research articles that cover an
array of stresses faced by microbes and their mechanisms to adapt and survive in adverse
conditions, including reviews discussing colonization resistance (Woelfel et al.),
antibiotic resistance (Abbas et al.), microbial persistence (Conlon et al.), and phage
resistance (Aranguren et al.). Reviews covering inter-bacterial warfare (Kennedy and
Comstock), nutrient acquisition (Muramatsu and Winter), and bacterial-drug interactions
(Cuesta-Zuluaga et al.) are also presented. Within this guide, primary research articles
expand our understanding on the arsenal employed by different microbes under inhospitable
conditions, including antibiotic exposure in the urinary tract (Amoura et al.), pathogen
expansion by exploiting or limiting host response (Yoo et al. and Szczesna et al.),
microbial enzymatic metabolism during endobiotic homeostasis (Simpson et al.), and
the phage-bacteria relationship (Benz et al.). Cover design by artist Rui Xie.",A,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_7.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_7.png,groundtruth,32_7.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,vith,31_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/15_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/15_4.png,clip,15_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,vitg,30_3.txt,train
ACS Applied Optical Materials,2024_8,Which of the following options best describe the cover story?,"Designing ternary nanocomposites consisting of ZnO@MoS2 core-shell heterostructures and conducting polymer polyaniline results in the generation of multiple excitons. These novel materials exhibit great saturable absorption behavior, which can be further implemented in nonlinear photonic devices.",C,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_1.png,clip,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_8.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,vitg,2023_12.txt,train
NATURE GENETICS,56_10,Which of the following options best describe the cover story?,"Brassica oleracea pan-genome
De novo genome assemblies of 22 Brassica oleracea accessions and pan-genome analyses highlight the effects of structural variation on gene expression and its contribution to morphotype diversification.
See Li et al.
Image: Chang Keyong, professional photographer, Beijing, China. Cover Design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/NATURE GENETICS/51_9.png,MAC_Bench/Nature/Cover/NATURE GENETICS/51_9.png,vith,51_9.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_1.png,clip,56_1.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/53_8.png,MAC_Bench/Nature/Cover/NATURE GENETICS/53_8.png,vitg,53_8.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_10.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_10.png,groundtruth,56_10.txt,train
Nature Water,2_4,Which of the following options best describe the cover story?,"The state of women in the water domain
While women are underrepresented in the formal water workforce, especially in low- and middle-income countries, they are highly overrepresented in the unpaid work of managing water, sanitation and hygiene (WASH) resources at the household level. The study by Caruso et al. examines whether women’s central role in household WASH has been exploited by WASH research and intervention activities. Reviewing previous WASH studies, they found the majority of interventions to be either gender-unequal or gender-unaware, and that many had relied entirely on participation by female household members for programme success. The authors discuss the risk of taking women’s time and work for granted and how it risks cementing gender inequalities in the water domain.
See Caruso, B. A. et al.
Image: Hugh Sitton / Photodisc / Getty Images. Cover design: Debbie Maizels",C,MAC_Bench/Nature/Cover/Nature Water/2_2.png,MAC_Bench/Nature/Cover/Nature Water/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,ave_2,2_1.txt,MAC_Bench/Nature/Cover/Nature Water/2_4.png,MAC_Bench/Nature/Cover/Nature Water/2_4.png,groundtruth,2_4.txt,MAC_Bench/Nature/Cover/Nature Water/1_10.png,MAC_Bench/Nature/Cover/Nature Water/1_10.png,ave_3,1_10.txt,train
Nature Mental Health,2_9,Which of the following options best describe the cover story?,"Sex and the brain across the lifespan
How the brain changes as a function of sex and as we age are profound and relatively under-researched questions. The April cover challenges us to consider the maturation stages that make up the developmental trajectory over the lifespan and suggest the different windows of time in which the interplay of systems is especially salient, such as neuroendocrine function and puberty.
See our Editorial for more insights into sex and the brain across the lifespan.
Image and cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Mental Health/2_12.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_12.png,clip,2_12.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_9.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_9.png,groundtruth,2_9.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Mental Health/1_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_10.png,vitg,1_10.txt,train
Trends in Biochemical Sciences,49_3,Which of the following options best describe the cover story?,"Liquid-Liquid Phase Separation (LLPS) is an emerging concept that
explains how membraneless cellular compartments and macromolecules organize
themselves while maintaining mobility. On pages 888–900 in this issue, Choi et al.
review presynaptic proteins that undergo LLPS and explore its potential contribution
to presynaptic compartmentalization and function. They also highlight the limitations
in this field and suggest future directions for understanding the role of LLPS in
presynapses and neurodegenerative diseases. Cover image by Jiyoung Choi and
Daehun Park.",A,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_3.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_3.png,groundtruth,49_3.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,vitg,47_14.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_8.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_8.png,clip,40_8.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_5.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_5.png,vith,49_5.txt,train
Nature Reviews Clinical Oncology,21_11,Which of the following options best describe the cover story?,"Risk factors for lung cancer in individuals who have never smoked, inspired by the Review on p121.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_4.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_4.png,ave_2,19_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_4.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_4.png,clip,21_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_3.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_3.png,vitg,18_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_11.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_11.png,groundtruth,21_11.txt,train
Nature Sustainability,7_8,Which of the following options best describe the cover story?,"Jobs in transition
A more sustainable economic system will have substantial effects on employment as sectors will downsize and jobs will be lost while emerging industries will need new workforce. This Focus issue highlights the likely effects of a sustainability transition on jobs and the barriers that both research and policy should overcome to facilitate such a transition.
See Focus page here
Image and cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Sustainability/5_9.png,MAC_Bench/Nature/Cover/Nature Sustainability/5_9.png,clip,5_9.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_8.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_8.png,groundtruth,7_8.txt,MAC_Bench/Nature/Cover/Nature Sustainability/6_11.png,MAC_Bench/Nature/Cover/Nature Sustainability/6_11.png,vitg,6_11.txt,MAC_Bench/Nature/Cover/Nature Sustainability/6_1.png,MAC_Bench/Nature/Cover/Nature Sustainability/6_1.png,vith,6_1.txt,train
ACS Catalysis,2024_24,Which of the following options best describe the cover story?,Artificial photosynthesis to produce solar fuels is a crucial field of research due to the global energy crisis.,C,MAC_Bench/ACS/Cover/ACS Catalysis/2011_3.png,MAC_Bench/ACS/Cover/ACS Catalysis/2011_3.png,clip,2011_3.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2021_24.png,MAC_Bench/ACS/Cover/ACS Catalysis/2021_24.png,ave_2,2021_24.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_24.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_24.png,groundtruth,2024_24.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2023_2.png,MAC_Bench/ACS/Cover/ACS Catalysis/2023_2.png,ave_1,2023_2.txt,train
Nature Aging,4_3,Which of the following options best describe the cover story?,"Better diets for planetary and cognitive health
In this issue, Gonçalves et al use longitudinal data from the ELSA-Brasil study to explore how adherence to the planetary health diet is linked to protection against cognitive decline, but with income as a modifier. The cover image shows a selection of fresh food that reflects the sustainable, plant-forward diet guidelines.
See Gonçalves et al.
Image: Adehoidar/iStock/Getty Images Plus. Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Aging/1_2.png,MAC_Bench/Nature/Cover/Nature Aging/1_2.png,ave_2,1_2.txt,MAC_Bench/Nature/Cover/Nature Aging/1_9.png,MAC_Bench/Nature/Cover/Nature Aging/1_9.png,ave_3,1_9.txt,MAC_Bench/Nature/Cover/Nature Aging/4_3.png,MAC_Bench/Nature/Cover/Nature Aging/4_3.png,groundtruth,4_3.txt,MAC_Bench/Nature/Cover/Nature Aging/2_10.png,MAC_Bench/Nature/Cover/Nature Aging/2_10.png,clip,2_10.txt,train
Accounts of Chemical Research,2025_4,Which of the following options best describe the cover story?,"With the advantage of the design flexibly in the substitution pattern of triptycene, at both the 1,8,13 and opposite tripodal 4,5,16 positions or the bridgehead 10 position, it is possible to create a wide variety of building blocks for the fabrication of highly organized, functional multi- and monolayer films on solid supports. View the article.",A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_5.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_5.png,vitg,2012_5.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_7.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_7.png,vith,2012_7.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,clip,2024_17.txt,train
Journal of Proteome Research,2024_12,Which of the following options best describe the cover story?,"The molecular environment of colorectal cancer can be compared to a localized oceanic system, where the fishing boat's light symbolizes transcriptomics technology and the diver's headlamp signifies proteomics technology. With the simultaneous utilization of both of these cutting-edge technologies, we can effectively and accurately observe changes in the molecular phenotype of colorectal cancer. Cover art designed by Jingjing Liu and completed by Jing Yuang Chao Feng.  View the article.",D,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_9.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_9.png,ave_2,2016_9.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_3.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_3.png,ave_1,2024_3.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_7.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_7.png,clip,2016_7.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_12.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_12.png,groundtruth,2024_12.txt,val
Nature Reviews Physics,6_12,Which of the following options best describe the cover story?,"The cover of this issue shows an artistic representation of the equations of state of the periodic table elements, calculated using two all-electron codes in each of the 10 crystal structure configurations shown on the table. See Bosoni et al.
Image: Giovanni Pizzi, EPFL, Switzerland. Cover design: Susanne Harris.",A,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_12.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_12.png,groundtruth,6_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,vith,4_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_4.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_4.png,vitg,5_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_9.png,clip,3_9.txt,train
BDJ Student,31_3,Which of the following options best describe the cover story?,"Vol 31 | Issue 1
In this January edition of BDJ Student, our lead article asks - and answers - how to be an ally
Cover illustration by Cat Sims",B,MAC_Bench/Nature/Cover/BDJ Student/29_2.png,MAC_Bench/Nature/Cover/BDJ Student/29_2.png,vith,29_2.txt,MAC_Bench/Nature/Cover/BDJ Student/31_3.png,MAC_Bench/Nature/Cover/BDJ Student/31_3.png,groundtruth,31_3.txt,MAC_Bench/Nature/Cover/BDJ Student/28_3.png,MAC_Bench/Nature/Cover/BDJ Student/28_3.png,ave_3,28_3.txt,MAC_Bench/Nature/Cover/BDJ Student/30_1.png,MAC_Bench/Nature/Cover/BDJ Student/30_1.png,clip,30_1.txt,val
Acta Pharmacologica Sinica,46_1,Which of the following options best describe the cover story?,"Cover Credit: Under transient middle cerebral artery occlusion (tMCAO) and oxygen-glucose deprivation/reoxygenation (OGD/Re) condition in vivo and in vitro, astrocyte-derived VEGFD activates the VEGF receptor 3 (VEGFR3) located on the membrane of astrocytes and microglia, respectively, disrupting astrocytic interleukin-3 (IL-3)/microglial IL-3 receptor α (IL-3Rα) crosstalk, leading to the activation of A1 astrocytes and M1 microglia and elevated neuroinflammatory cytokines. The disruption of this crosstalk between IL-3 and IL-3Rα induces lipid metabolic reprogramming of microglia evidenced by upregulating CPT1A expression, a rate-limiting enzyme for the mitochondrial β-oxidation, causing accumulated lipid droplets (LDs), activated microglia and neuroinflammation, reduced glycerophospholipids levels, microglial phagocytosis dysfunction and necrosis, as well as neuronal cell death. The therapeutic interventions by VEGFR antagonist axitinib or exogenous IL-3 can reestablish the IL-3/IL-3Rα crosstalk, reducing astrocytes and microglia activation, LDs accumulation and neuroinflammation, and restoring microglial phagocytotic function, ultimately contributing to brain recovery from tMCAO insult. (DOI 10.1038/s41401-024-01405-6). See the article in pages 292–307",A,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/46_1.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/46_1.png,groundtruth,46_1.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_11.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_11.png,vith,43_11.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_3.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_3.png,clip,43_3.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_3.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_3.png,vitg,42_3.txt,val
ACS Applied Nano Materials,2025_1,Which of the following options best describe the cover story?,"A dynamic interplay of reaction trajectories on the synthesis landscape: Guiding gold and silica trajectories to intersect results in Au@mSiO2 nanoparticles that exhibit plasmonic heating capabilities, bridging nanoscale precision with macroscopic applications.",B,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_1.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_1.png,vitg,2020_1.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_7.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_9.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_9.png,vith,2020_9.txt,test
Nature Water,2_5,Which of the following options best describe the cover story?,"Isotope monitoring of river flow dynamics
River flow dynamics, encompassing all interactions and processes that regulate water movements within river systems, are influenced by various factors such as precipitation and land use. Understanding these dynamics is essential for water resource management within ongoing hydroclimate and land-use changes. By analysing stable isotopes in water molecules from rivers globally, Vystavna and colleagues identify the young water fraction (<2−3months) and introduce an indicator of dynamic water retention that shows river flow dynamics are influenced by land use and hydroclimate characteristics. The cover shows the Schlögener Schlinge in the upper Danube valley in Austria, where the Danube almost forms a circle. In large river catchments like the Danube, contributing tributaries exhibit varied catchment and climate characteristics, leading to contrasting trends in young water fraction and dynamic water retention.
See Vystavna et al.
Image: Walter Geiersperger/Corbis Documentary/Getty Images. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Water/3_1.png,MAC_Bench/Nature/Cover/Nature Water/3_1.png,vitg,3_1.txt,MAC_Bench/Nature/Cover/Nature Water/2_5.png,MAC_Bench/Nature/Cover/Nature Water/2_5.png,groundtruth,2_5.txt,MAC_Bench/Nature/Cover/Nature Water/1_2.png,MAC_Bench/Nature/Cover/Nature Water/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,vith,2_1.txt,val
Trends in Ecology & Evolution,39_1,Which of the following options best describe the cover story?,"Rules of fair allocation could be used to fairly divide the costs of
biodiversity impact abatement, to achieve global biodiversity goals and remain within
a safe and just development space. On pages 1102–1110, Hollie Booth and colleagues
discuss how rules of fair allocation could be applied to biodiversity decision-making,
to operationalize equity and create space for cooperatively and constructively
negotiating avoidance liabilities within biodiversity impact mitigation. The cover
image
shows small-scale fishing vessels in Aceh Jaya, Indonesia. After establishment of
a
no-take zone (NTZ), rules such as “weighted equal division” or “divide and choose”
could be used to fairly distribute the opportunity costs associated with restricting
fi shing activity in the NTZ. Photo credit: Francesca Page.",D,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/35_7.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/35_7.png,vith,35_7.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_11.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_11.png,vitg,36_11.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/32_4.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/32_4.png,clip,32_4.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_1.png,groundtruth,39_1.txt,val
ACS Omega,2025_5,Which of the following options best describe the cover story?,"Low-dimensional TMDC-based flexible, electrochemical biosensors.",D,MAC_Bench/ACS/Cover/ACS Omega/2022_34.png,MAC_Bench/ACS/Cover/ACS Omega/2022_34.png,clip,2022_34.txt,MAC_Bench/ACS/Cover/ACS Omega/2022_31.png,MAC_Bench/ACS/Cover/ACS Omega/2022_31.png,vith,2022_31.txt,MAC_Bench/ACS/Cover/ACS Omega/2021_11.png,MAC_Bench/ACS/Cover/ACS Omega/2021_11.png,vitg,2021_11.txt,MAC_Bench/ACS/Cover/ACS Omega/2025_5.png,MAC_Bench/ACS/Cover/ACS Omega/2025_5.png,groundtruth,2025_5.txt,train
Crystal Growth & Design,2024_17,Which of the following options best describe the cover story?,The Cr-doped large single-crystal diamond was synthesized under a high pressure and high temperature. The addition of Cr reduces the nitrogen content in the diamond. A low nitrogen synthesis environment is more conducive to the doping of Cr atoms into the diamond lattice. The Cr atom exists in the diamond in the form of Cr,C,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,vitg,2019_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_6.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_6.png,clip,2017_6.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_17.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2023_9.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2023_9.png,ave_2,2023_9.txt,train
Trends in Microbiology,32_11,Which of the following options best describe the cover story?,"The cover schematic summarizes the heterogeneity of Mycobacterium
   tuberculosis, the bacterial pathogen responsible for tuberculosis, upon treatment with
antibiotics. When treated with antibiotics, some mycobacteria will perish while other
mycobacteria will localize in specific environments (represented under an umbrella)
protected from the antibiotics. Given the pressing need for rapid, cost-effective
and
potent anti-tuberculous drugs, a more critical examination of the contribution of
host
environments with regards to antibiotic distribution and efficacy is highly relevant.
These concepts are discussed in the Review article by Dr. Day and colleagues.
Image courtesy: Dr. Noémie Matthey",D,MAC_Bench/Cell/Cover/Trends in Microbiology/21_10.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_10.png,vitg,21_10.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/16_2.png,MAC_Bench/Cell/Cover/Trends in Microbiology/16_2.png,clip,16_2.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/29_7.png,MAC_Bench/Cell/Cover/Trends in Microbiology/29_7.png,vith,29_7.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_11.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_11.png,groundtruth,32_11.txt,val
Nature Chemical Biology,20_1,Which of the following options best describe the cover story?,"A mark for degradation
Seabrook et al. developed MrTAC, a targeted protein degradation modality using arginine methylation to shuttle intracellular proteins to lysosomes for rapid degradation. The cover shows a confocal microscopy image of methylated proteins (gold) in HeLa cells organizing into cytosolic puncta with a nuclear costain (DAPI, blue).
See Seabrook et al. and Research Briefing
Image: Laurence Seabrook, University of California, Irvine. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_7.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_7.png,clip,17_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_8.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_8.png,ave_2,14_8.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_8.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_8.png,vitg,20_8.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_1.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_1.png,groundtruth,20_1.txt,test
Cell Host&Microbe,33_2,Which of the following options best describe the cover story?,"On the cover: This illustration by Jiang et al. metaphorically represents the gut and brain as intricate mazes connected by the vagus
nerve. The NTS (nucleus tractus solitarius) acts as a signal controller, illustrated
as a traffic control center that manages neural signals at the CeA (central amygdala).
Roseburia intestinalis, portrayed as diligent workers in the lush, maze-like forest, produce butyrate, symbolized
by the yellow “fuel”. This butyrate powers the NTS and allows it to signal “red lights”
(inhibitory output) at the CeA, effectively blocking pro-nociceptive signals (the
“cars”) from traveling along the ascending pain pathway from the spinal cord. This
study reveals a mechanism of pain regulation via the gut-brain axis and underscores
the significant influence of microbiota-derived metabolites on pain-related neural
circuitry. This cover image was created by Beatrix Yu, a medical illustrator at CUHK.",A,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_2.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_2.png,groundtruth,33_2.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,ave_3,27_5.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/23_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/23_3.png,vitg,23_3.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_1.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_1.png,clip,33_1.txt,test
NATURE REVIEWS NEUROSCIENCE,25_10,Which of the following options best describe the cover story?,"‘Light and cognition’, inspired by the Review on p159.
Cover design: Jennie Vallis",B,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_10.png,groundtruth,25_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,vitg,25_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_11.png,vith,22_11.txt,train
Cell Systems,15_4,Which of the following options best describe the cover story?,"On the cover: Droplets containing algae and bacteria on a kChip microfluidic chip.
In this issue of Cell Systems, Gopalakrishnappa et al. use high-throughput screening of >100,000 algae-bacteria communities in ∼525 environments
and find that pH, buffering capacity, and carbon source identity modulate algae-bacteria
interactions by impacting the dependence of growth on nutrient availability. Image
credit: the authors.",B,MAC_Bench/Cell/Cover/Cell Systems/1_4.png,MAC_Bench/Cell/Cover/Cell Systems/1_4.png,vitg,1_4.txt,MAC_Bench/Cell/Cover/Cell Systems/15_4.png,MAC_Bench/Cell/Cover/Cell Systems/15_4.png,groundtruth,15_4.txt,MAC_Bench/Cell/Cover/Cell Systems/13_6.png,MAC_Bench/Cell/Cover/Cell Systems/13_6.png,clip,13_6.txt,MAC_Bench/Cell/Cover/Cell Systems/12_11.png,MAC_Bench/Cell/Cover/Cell Systems/12_11.png,vith,12_11.txt,train
Cell Reports,43_6,Which of the following options best describe the cover story?,"Some wild Mimulus verbenaceus plants in Sedona, AZ, USA display a distinct anthocyanin
stripe across their leaves. In this issue, LaFountain et al. identify three regulatory genes that pre-pattern the foliar stripe and are associated
with leaf development. These findings suggest that the stripe phenotype was potentiated
by the incorporation of an anthocyanin regulatory gene into a pre-existing genetic
regulatory network and provide insights into how phenotypic novelties emerge. Concept
and Artwork: Bianca T. Ferreira.",A,MAC_Bench/Cell/Cover/Cell Reports/43_6.png,MAC_Bench/Cell/Cover/Cell Reports/43_6.png,groundtruth,43_6.txt,MAC_Bench/Cell/Cover/Cell Reports/8_1.png,MAC_Bench/Cell/Cover/Cell Reports/8_1.png,vith,8_1.txt,MAC_Bench/Cell/Cover/Cell Reports/16_1.png,MAC_Bench/Cell/Cover/Cell Reports/16_1.png,vitg,16_1.txt,MAC_Bench/Cell/Cover/Cell Reports/6_6.png,MAC_Bench/Cell/Cover/Cell Reports/6_6.png,clip,6_6.txt,test
Nature Reviews Bioengineering,2_3,Which of the following options best describe the cover story?,"Biomaterials can be engineered to allow their minimally-invasive delivery by injection. Such injectable biomaterials face distinct design considerations, taking into account means of injection, geometry of the injection device, injection target, duration and force, and viscosity of the material. See Michael Nguyen et al
Cover image: Simon Bradbrook",A,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_3.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_3.png,groundtruth,2_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_2.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_2.png,ave_3,2_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,vith,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,clip,3_1.txt,val
Nature Cell Biology,26_5,Which of the following options best describe the cover story?,"Multi-organelle units
OrgaPlexing — an imaging pipeline to map metabolic organelles and their interactions — reveals changes in mitochondria, endoplasmic reticulum, peroxisome and lipid droplet dynamics that affect macrophage inflammatory lipid mediator synthesis.
See Zimmermann et al. and News & Views by Kleele
Image: Julia Zimmermann and Angelika Rambold, ""Organelle-Networks Immunology” Lab, Max Planck Institute of Immunobiology and Epigenetics. Cover design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Cell Biology/26_5.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_5.png,groundtruth,26_5.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/21_10.png,MAC_Bench/Nature/Cover/Nature Cell Biology/21_10.png,clip,21_10.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/21_7.png,MAC_Bench/Nature/Cover/Nature Cell Biology/21_7.png,ave_3,21_7.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/20_10.png,MAC_Bench/Nature/Cover/Nature Cell Biology/20_10.png,vitg,20_10.txt,val
Nature Computational Science,4_1,Which of the following options best describe the cover story?,"An integrative data-driven model of C. elegans
BAAIWorm, a computational model of C. elegans, integrates a biophysically detailed neural network with a three-dimensional biomechanical body, simulating behavior within an interactive environment. The cover image depicts the simulation of a C. elegans and its epithelial system.
See Zhao et al.
Image: Copyright 2024, Lei Ma and Yong Guo. Cover design: Alex Wing",B,MAC_Bench/Nature/Cover/Nature Computational Science/3_9.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_1.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_1.png,groundtruth,4_1.txt,MAC_Bench/Nature/Cover/Nature Computational Science/1_10.png,MAC_Bench/Nature/Cover/Nature Computational Science/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_2.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_2.png,vith,3_2.txt,train
Science Signaling,2007_402,Which of the following options best describe the cover story?,"COVER This week features a Perspective on roles for Toll-like receptors in development of the central nervous system and in the response to neuronal injury. [Image: Christopher Bickel, AAAS]",A,MAC_Bench/Science/Cover/Science Signaling/2007_402.png,MAC_Bench/Science/Cover/Science Signaling/2007_402.png,groundtruth,2007_402.txt,MAC_Bench/Science/Cover/Science Signaling/7_336.png,MAC_Bench/Science/Cover/Science Signaling/7_336.png,vitg,7_336.txt,MAC_Bench/Science/Cover/Science Signaling/2_59.png,MAC_Bench/Science/Cover/Science Signaling/2_59.png,clip,2_59.txt,MAC_Bench/Science/Cover/Science Signaling/3_136.png,MAC_Bench/Science/Cover/Science Signaling/3_136.png,vith,3_136.txt,train
Nature Climate Change,14_6,Which of the following options best describe the cover story?,"Zooming in on small island states
Small island states and territories are not only vulnerable to climate change but are also leaders in international climate negotiations and in adapting to changing environments. In this issue, we feature a Viewpoint that highlights research conducted on different island states and territories around the world and a Comment and Correspondence that propose ways forward to better understand climate change impacts and to translate research into action on large ocean islands.
See Viewpoint , Evans et al. and Leal Filho et al.
Image: Universal Images Group North America LLC / Alamy Stock Photo. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Climate Change/8_3.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_3.png,vitg,8_3.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_6.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_6.png,groundtruth,14_6.txt,MAC_Bench/Nature/Cover/Nature Climate Change/8_11.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_11.png,clip,8_11.txt,MAC_Bench/Nature/Cover/Nature Climate Change/13_9.png,MAC_Bench/Nature/Cover/Nature Climate Change/13_9.png,vith,13_9.txt,train
Accounts of Chemical Research,2024_22,Which of the following options best describe the cover story?,"liquid phase separation (LLPS), can result in diverse supramolecular structures, ranging from highly ordered forms to more disordered organizations, such as droplets or glasses. View the article.",C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2011_7.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2011_7.png,vith,2011_7.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_2.png,clip,2022_2.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_22.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_18.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_18.png,vitg,2022_18.txt,train
CHEMICAL REVIEWS,2025_4,Which of the following options best describe the cover story?,"Electronic nanochips offer electric fields that are able to precisely modulate molecular activities from molecular movements and physical properties to chemical reactions and optoelectronic functions. The utilization of electric fields to manipulate molecular behaviors on the nanoscale is a new research field that can inspire curiosity and lead to innovative discoveries of new quantum effects and new chemistry, improving our understanding of the molecular world.",D,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_10.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_10.png,clip,2019_10.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_3.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_3.png,ave_1,2019_3.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_4.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_4.png,ave_2,2016_4.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_4.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_4.png,groundtruth,2025_4.txt,train
Nature Metabolism,7_1,Which of the following options best describe the cover story?,"Multifaceted myokines
Two concurrent studies highlight the dual role of feimin, a feeding-induced myokine, in regulating glucose homeostasis as well as physical performance during exercise. The image depicts staining of fibre types in the soleus muscle.
See Shi, X., Hu, X., Fang, X. et al. and Peng, Y., Jia, L. et al.
Image: Ying Peng. Cover Design: Thomas Phillips.",C,MAC_Bench/Nature/Cover/Nature Metabolism/1_1.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_11.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_11.png,vith,3_11.txt,MAC_Bench/Nature/Cover/Nature Metabolism/7_1.png,MAC_Bench/Nature/Cover/Nature Metabolism/7_1.png,groundtruth,7_1.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_7.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_7.png,vitg,3_7.txt,train
Cell Reports,43_1,Which of the following options best describe the cover story?,"On the Cover: Two 3D reconstructions of the Arabidopsis thaliana root meristem, showing
the domains of transcription and translation (in magenta) and protein accumulation
(in green) of the transcription factor MONOPTEROS. In this issue, Cavalleri et al. report that MONOPTEROS protein is stable in tissues with high auxin content, while
accumulation is prevented by proteasomal degradation in domains with low auxin. This
regulation is required to correctly modulate root development and sensitivity to auxin.
Image credit: Alex Cavalleri.",B,MAC_Bench/Cell/Cover/Cell Reports/2_3.png,MAC_Bench/Cell/Cover/Cell Reports/2_3.png,vith,2_3.txt,MAC_Bench/Cell/Cover/Cell Reports/43_1.png,MAC_Bench/Cell/Cover/Cell Reports/43_1.png,groundtruth,43_1.txt,MAC_Bench/Cell/Cover/Cell Reports/34_12.png,MAC_Bench/Cell/Cover/Cell Reports/34_12.png,clip,34_12.txt,MAC_Bench/Cell/Cover/Cell Reports/35_12.png,MAC_Bench/Cell/Cover/Cell Reports/35_12.png,vitg,35_12.txt,test
Nature Photonics,18_5,Which of the following options best describe the cover story?,"Stretchable displays
A soft ribbon-shaped perovskite electroluminescent display simultaneously offers multicolour output, stretchability, high brightness, and double-sided emission. This dynamic display capability holds promise for broad applications in interactive wearable devices, artificial skin, and soft robotics.
See Chun et al.
Image: Dr. Fengjun Chun, City University of Hong Kong. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Photonics/1_2.png,MAC_Bench/Nature/Cover/Nature Photonics/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Photonics/14_3.png,MAC_Bench/Nature/Cover/Nature Photonics/14_3.png,vith,14_3.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_5.png,MAC_Bench/Nature/Cover/Nature Photonics/18_5.png,groundtruth,18_5.txt,MAC_Bench/Nature/Cover/Nature Photonics/17_8.png,MAC_Bench/Nature/Cover/Nature Photonics/17_8.png,vitg,17_8.txt,train
Analytical Chemistry,2025_5,Which of the following options best describe the cover story?,GPx4-mediated ferroptosis is a crucial mechanism in cellular oxidative stress responses. A field-deployable luciferase-based reporter sensor system was developed and used for  non-invasive detection of GPx4 expression in response to ferroptosis modulators in live mammalian cells.,B,MAC_Bench/ACS/Cover/Analytical Chemistry/2024_34.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2024_34.png,vitg,2024_34.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_5.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_4.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_4.png,ave_1,2022_4.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2023_22.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2023_22.png,clip,2023_22.txt,train
NATURE REVIEWS IMMUNOLOGY,24_2,Which of the following options best describe the cover story?,"Rheumatic disease, inspired by the Review on p781.
Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_6.png,clip,19_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_5.png,ave_2,19_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_5.png,vitg,23_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_2.png,groundtruth,24_2.txt,train
Industrial & Engineering Chemistry Research,2024_23,Which of the following options best describe the cover story?,fibrous structure were prepared by modulating the ratio of binary polymers and exhibit excellent mechanical properties.,D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_30.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_30.png,ave_1,2024_30.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_13.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_13.png,clip,2021_13.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_20.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_20.png,vith,2021_20.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_23.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_23.png,groundtruth,2024_23.txt,train
Cell Stem Cell,31_5,Which of the following options best describe the cover story?,"On the cover: In this issue, Landau, Zhao, et al. demonstrate that incorporating pluripotent stem cell-derived macrophages restores
cell-circuit interactions, enabling enhanced contractility and stable vascularization
of engineered cardiac tissues. Through single-cell sequencing, the authors demonstrate
that primitive macrophages act on stromal cells to enhance their angiogenic potential
in cardiac tissues. Shown in the image as construction workers, macrophages contribute
through both direct physical interactions and extracellular matrix (ECM) interactions.
This results in the development of functional, perfusable vasculature, as evidenced
by the flowing blue beads in the vessel network. Image courtesy of the authors.",D,MAC_Bench/Cell/Cover/Cell Stem Cell/24_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/24_1.png,vith,24_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/23_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/23_4.png,clip,23_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/28_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/28_4.png,vitg,28_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_5.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_5.png,groundtruth,31_5.txt,train
Nature Reviews Cardiology,21_12,Which of the following options best describe the cover story?,"Use of AI for imaging of coronary atherosclerosis, inspired by the Roadmap on p51.
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_8.png,clip,20_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_12.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_12.png,groundtruth,21_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_7.png,vith,18_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_12.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_12.png,ave_1,18_12.txt,train
Trends in Cancer,10_1,Which of the following options best describe the cover story?,"In this issue, Haase et al. discuss how advances in transcriptomic
and epigenomic profiling can uncover new pediatric high-grade glioma subtypes
and inform on new epigenetic-based therapeutic strategies for clinical translation.
The cover depicts an abstract representation of epigenetic reprograming leading
to tumor eradication illustrated by the life cycle of the Monarch butterfly. The brain
tumor is illustrated by the leaf and the eggs embedded in the brain. The stages
of the monarch’s life cycle represents the epigenetic reprogramming of the tumor,
going from the chrysalis to mature butterflies symbolizing epigenetic reprograming
within tumor cells. The flowers represent the fuel needed by the butterflies to mature
and thrive. The image also depicts DNA wrapping around histone subunits forming
the nucleosome, which are responsible for the proper packaging of the chromatin.
Upon epigenetic reprograming, the structure of the chromatin changes enabling the
expression of genetic programs the mediate tumor cell death or activation of immune
pathways, enabling the demise of the tumors, exemplified by the damaged butterfly
at
the top right of the image. Cover image designed by Ella Maru Studio, Inc.",A,MAC_Bench/Cell/Cover/Trends in Cancer/10_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_1.png,groundtruth,10_1.txt,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,clip,3_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/3_11.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_11.png,ave_3,3_11.txt,MAC_Bench/Cell/Cover/Trends in Cancer/4_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_6.png,ave_2,4_6.txt,train
Nature Geoscience,17_8,Which of the following options best describe the cover story?,"Clouds and climate sensitivity
Clouds are the leading source of uncertainty in predicting climate change because they strongly influence Earth’s energy balance, yet how they interact with the climate system is not well understood. Tropical anvil clouds produced by thunderstorms are particularly important because they reflect sunlight and trap thermal radiation, but their fate in a warming world is unclear. The image shows anvil clouds casting shadows over the Amazon rainforest.
See McKim et al.
Image: Earth Science and Remote Sensing Unit, NASA Johnson Space Center. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Geoscience/15_12.png,MAC_Bench/Nature/Cover/Nature Geoscience/15_12.png,vitg,15_12.txt,MAC_Bench/Nature/Cover/Nature Geoscience/14_10.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_10.png,clip,14_10.txt,MAC_Bench/Nature/Cover/Nature Geoscience/3_9.png,MAC_Bench/Nature/Cover/Nature Geoscience/3_9.png,vith,3_9.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_8.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_8.png,groundtruth,17_8.txt,train
Nature Geoscience,17_4,Which of the following options best describe the cover story?,"Electric gold nugget formation in quartz
Quartz emits a piezoelectric charge during deformation that may promote the formation of gold nuggets within veins in orogenic settings that experience earthquakes, according to a study using quartz deformation experiments and piezoelectric modelling. This image presents a false-coloured X-ray tomography reconstruction of gold in quartz from the Discovery orogenic gold deposit located northeast of Yellow Knife, Northwest Territories, Canada.
See Voisey et al.
Image: Chris Voisey, Monash University. Cover design: Alex Wing",B,MAC_Bench/Nature/Cover/Nature Geoscience/6_6.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_6.png,vith,6_6.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_4.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_4.png,groundtruth,17_4.txt,MAC_Bench/Nature/Cover/Nature Geoscience/13_8.png,MAC_Bench/Nature/Cover/Nature Geoscience/13_8.png,vitg,13_8.txt,MAC_Bench/Nature/Cover/Nature Geoscience/16_3.png,MAC_Bench/Nature/Cover/Nature Geoscience/16_3.png,clip,16_3.txt,test
ACS Sustainable Resource Management,2024_7,Which of the following options best describe the cover story?,The cover depicts a tailored delivery of metal-based nanofertilizers with ionic liquids for enhanced efficiency and reduced metal ion accumulation.,C,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,ave_2,2024_10.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,ave_1,2024_8.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_7.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,clip,2024_9.txt,train
Science Signaling,2007_414,Which of the following options best describe the cover story?,COVER This week features a  Perspective that discusses how the activity of SOS is regulated by the binding of an allosteric Ras molecule. The image shows SOS and two molecules of Ras based on PDB 1nvu.,D,MAC_Bench/Science/Cover/Science Signaling/2_63.png,MAC_Bench/Science/Cover/Science Signaling/2_63.png,clip,2_63.txt,MAC_Bench/Science/Cover/Science Signaling/5_245.png,MAC_Bench/Science/Cover/Science Signaling/5_245.png,vith,5_245.txt,MAC_Bench/Science/Cover/Science Signaling/2_54.png,MAC_Bench/Science/Cover/Science Signaling/2_54.png,ave_1,2_54.txt,MAC_Bench/Science/Cover/Science Signaling/2007_414.png,MAC_Bench/Science/Cover/Science Signaling/2007_414.png,groundtruth,2007_414.txt,train
Industrial & Engineering Chemistry Research,2024_21,Which of the following options best describe the cover story?,Scaling laws for fluid flow and heat transfer analysis of packed beds filled with mono-sized pebbles.,A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_21.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_21.png,groundtruth,2024_21.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,ave_1,2022_11.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_51.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_51.png,clip,2024_51.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_17.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_17.png,vith,2021_17.txt,train
ACS Applied Energy Materials,2025_5,Which of the following options best describe the cover story?,"The image depicts a lanthanum hydride cluster nanoconfined within the porous structure of functionalized carbon hosts, highlighting local interactions between the hydride cluster and the carbon material.  View the article.",A,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2025_5.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2023_6.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2023_6.png,vitg,2023_6.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2022_10.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2022_10.png,clip,2022_10.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2021_3.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2021_3.png,vith,2021_3.txt,train
Molecular Plant,17_7,Which of the following options best describe the cover story?,"On the cover: The cover image illustrates a satellite in orbit over agricultural landscapes, symbolizing
the integration of satellite-enabled enviromics to enhance crop improvement. The satellite-enabled
enviromics leverage high-throughput remote sensing to achieve detailed genotype-by-environment
objectives, transforming predictive breeding and enabling targeted genotype selection
for maximum productivity under varying environmental conditions. Image by Rafael T.
Resende with the assistance of AI: Bing images and chatgpt4/DALL⋅E.",B,MAC_Bench/Cell/Cover/Molecular Plant/18_2.png,MAC_Bench/Cell/Cover/Molecular Plant/18_2.png,vitg,18_2.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_7.png,MAC_Bench/Cell/Cover/Molecular Plant/17_7.png,groundtruth,17_7.txt,MAC_Bench/Cell/Cover/Molecular Plant/9_6.png,MAC_Bench/Cell/Cover/Molecular Plant/9_6.png,vith,9_6.txt,MAC_Bench/Cell/Cover/Molecular Plant/12_5.png,MAC_Bench/Cell/Cover/Molecular Plant/12_5.png,clip,12_5.txt,train
NATURE BIOTECHNOLOGY,42_9,Which of the following options best describe the cover story?,"Whole-body imaging
Image of a whole mouse body with depth color-coding of a neuronal marker. Mai et al. present wildDISCO, a method for whole-body imaging compatible with standard IgG antibody labeling.
See Mai et al.
Image: Ali Ertürk, Hongcheng Mai, Jie Luo. Cover Design: Erin Dewalt.",D,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_12.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_12.png,ave_2,42_12.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_10.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_10.png,clip,41_10.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_1.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_1.png,vitg,39_1.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_9.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_9.png,groundtruth,42_9.txt,train
ACS ES&T Engineering,2024_7,Which of the following options best describe the cover story?,"A novel phosphorus-coordinated Pd@MXene catalyst achieved 80% Pd reduction, 3.9-fold higher efficiency, and comparable performance to Pd@MX/CC in diclofenac removal. It maintained efficiency with wide pH ranges and 10 cycles, showing promise for water purification.",A,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_7.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_3.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_3.png,clip,2022_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2021_5.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2021_5.png,vith,2021_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2021_12.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2021_12.png,vitg,2021_12.txt,train
Molecular Therapy,32_5,Which of the following options best describe the cover story?,On the cover: Schematic representation of mRNA translation to protein by a ribosome from Tkaczyk et al. Image credit: Astra Zeneca.,B,MAC_Bench/Cell/Cover/Molecular Therapy/29_2.png,MAC_Bench/Cell/Cover/Molecular Therapy/29_2.png,vith,29_2.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_5.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_5.png,groundtruth,32_5.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_8.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_8.png,clip,31_8.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_3.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_3.png,vitg,31_3.txt,train
NATURE REVIEWS NEUROSCIENCE,25_5,Which of the following options best describe the cover story?,"‘Targeting genes for treatment’, inspired by the Review on p553.
Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/17_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/17_12.png,vith,17_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_8.png,vitg,24_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,clip,15_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_5.png,groundtruth,25_5.txt,train
ACS Measurement Science Au,2022_2,Which of the following options best describe the cover story?,"Despite its global importance in controlling the world's carbon dioxide levels, there is a lot we do not know about calcite dissolution. By studying the dissolution reaction at the single particle scale, we reveal the process to be limited by the diffusion of ions away from the mineral interface.",D,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_3.png,ave_2,2022_3.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,vitg,2022_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png,groundtruth,2022_2.txt,test
Nature Computational Science,4_6,Which of the following options best describe the cover story?,"Flexible graph neural networks for materials prediction
Recently, machine learning-based methods, including graph neural networks (GNNs), have been widely used to establish structure–property relationships, which are crucial guidelines for materials design. However, generalizing such models requires addressing critical technical challenges, such as handling material-dependent output dimensions. In this issue, Ryotaro Okabe et al. propose virtual node models to further generalize GNNs, enabling the prediction of material properties with variable output dimensions. The work introduces three virtual node approaches that can be applied to predicting different phonon spectra with higher computational efficiency when compared to state-of-the-art methods. The cover image depicts vibrations of atoms or phonons, which is the property that the virtual node GNN has been applied to predict.
See Ryotaro Okabe et al. and accompanying Research Briefing
Image: Yugora / DigitalVision Vectors / Getty Images. Cover design: Alex Wing.",D,MAC_Bench/Nature/Cover/Nature Computational Science/3_10.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_10.png,ave_2,3_10.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_12.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_12.png,ave_1,3_12.txt,MAC_Bench/Nature/Cover/Nature Computational Science/1_12.png,MAC_Bench/Nature/Cover/Nature Computational Science/1_12.png,clip,1_12.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_6.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_6.png,groundtruth,4_6.txt,train
Nature Chemistry,16_9,Which of the following options best describe the cover story?,"Monitoring molecular relaxation
Molecular photoswitches can be exploited for solar thermal energy storage and information processing. One such system involves the rapid conversion between the molecular isomers norbornadiene (an artistic representation of which is depicted on the cover) and quadricyclane; however, our understanding of the switching processes is incomplete. Daniel Rolles and co-workers have used time-resolved gas-phase extreme ultraviolet photoelectron spectroscopy combined with non-adiabatic molecular dynamics simulations to monitor the electronic relaxation of quadricyclane after ultraviolet excitation and have observed two competing relaxation pathways that occur on different timescales.
See Borne et al.
Image: Wojciech Nowikowski and Karl Harrison. Cover design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/Nature Chemistry/16_9.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_9.png,groundtruth,16_9.txt,MAC_Bench/Nature/Cover/Nature Chemistry/7_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/7_6.png,clip,7_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/14_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/14_6.png,vitg,14_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/15_7.png,MAC_Bench/Nature/Cover/Nature Chemistry/15_7.png,ave_0,15_7.txt,train
Trends in Biochemical Sciences,49_7,Which of the following options best describe the cover story?,"Osmotic stress conditions cause changes in the physicochemical
properties of the cellular environment, including macromolecular crowding. Recent
progress has shed light on how cells sense such environmental perturbations (e.g.
temperature, pH, and crowding). On pages 480–493 in this issue, Meneses-Reyes et al.
discuss how intrinsically disordered regions in proteins can sense macromolecular
crowding in plants and provide a tool guide for tracking macromolecular crowding in
living cells. Cover image by Cesar Cuevas-Velazquez, inspired by Mexican seed art.",A,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_7.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_7.png,groundtruth,49_7.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,vitg,47_14.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_12.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_12.png,clip,40_12.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,vith,50_2.txt,train
Journal of Chemical Education,2021_3,Which of the following options best describe the cover story?,"In celebration of the ACS National Chemistry Week 2021 theme ""Fast or Slow?Chemistry Makes It Go!"", the cover features snapshots of the Belousov-Zhabotinsky (BZ) reaction, a reaction that oscillates in both time and space. The complex chemical system shown involves bromate, bromide, malonic acid, sulfuric acid, ferroin indicator, and oxygen from the air. The oscillations in this reaction start with the formation of small pale blue dots in a rusty red solution, with each dot expanding in ever-widening concentric rings. By swirling the solution, the reaction can be repeated. Each time the reaction occurs, the oscillation pattern is different. (Images from the Journal of Chemical Education?s Chemistry Comes Alive! video collection.)",A,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_3.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_3.png,groundtruth,2021_3.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_4.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_4.png,ave_1,2016_4.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2022_9.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2022_9.png,vith,2022_9.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2015_3.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2015_3.png,clip,2015_3.txt,train
One Earth,7_3,Which of the following options best describe the cover story?,"On the cover: Blue foods and small-scale fisheries are vital for the resilience of
coastal communities, providing essential nutrition, economic stability, and cultural
identity. However, they face threats from overexploitation, climate change, and habitat
degradation. Inclusive governance of these resources is crucial for maintaining traditions
and ensuring economic and nutritional stability for current and future generations.
Image: Image Source, Getty.",C,MAC_Bench/Cell/Cover/One Earth/7_2.png,MAC_Bench/Cell/Cover/One Earth/7_2.png,ave_3,7_2.txt,MAC_Bench/Cell/Cover/One Earth/5_4.png,MAC_Bench/Cell/Cover/One Earth/5_4.png,clip,5_4.txt,MAC_Bench/Cell/Cover/One Earth/7_3.png,MAC_Bench/Cell/Cover/One Earth/7_3.png,groundtruth,7_3.txt,MAC_Bench/Cell/Cover/One Earth/2_4.png,MAC_Bench/Cell/Cover/One Earth/2_4.png,ave_2,2_4.txt,train
ACS Biomaterials Science & Engineering,2024_5,Which of the following options best describe the cover story?,"The visual represents the groundbreaking fabrication of 3D polycaprolactone macrostructures by 3D electrospinning. Highlighted are the optimal parameters that enable the precise construction of uniform, hydrophilic scaffolds, suitable for enhanced cell penetration and growth",A,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2024_5.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2020_1.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2020_1.png,clip,2020_1.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2018_7.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2018_7.png,ave_1,2018_7.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2021_9.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2021_9.png,vitg,2021_9.txt,train
Developmental Cell,59_4,Which of the following options best describe the cover story?,"On the cover: “Virtue Lies in Balance.” The image illustrates the origin of muscle
formation, starting with the muscle stem cell (in blue) and culminating in muscle
fibers (in pink), separated by a curve that embodies the precise balance governing
this transition. In the accompanying study, the authors show that perturbing this
metabolic balance during muscle stem cell differentiation leads to disproportionate
muscle development. To delve into the role of glutamine metabolism in muscle stem
cell fate, see Soro and Fitzgerald et al. Image credit: Maria de la Fuente Soro.",C,MAC_Bench/Cell/Cover/Developmental Cell/28_3.png,MAC_Bench/Cell/Cover/Developmental Cell/28_3.png,vitg,28_3.txt,MAC_Bench/Cell/Cover/Developmental Cell/16_2.png,MAC_Bench/Cell/Cover/Developmental Cell/16_2.png,clip,16_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_4.png,MAC_Bench/Cell/Cover/Developmental Cell/59_4.png,groundtruth,59_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/22_2.png,MAC_Bench/Cell/Cover/Developmental Cell/22_2.png,ave_0,22_2.txt,train
Nature Food,5_5,Which of the following options best describe the cover story?,"Irrigation in post-invasion Ukraine
In 2022, Ukraine was the world’s fifth-largest wheat exporter, fourth-largest maize exporter and third-largest rapeseed exporter. The country’s invasion by Russia caused damage to Ukrainian crop production lands and irrigation systems, resulting in shocks to global grain markets and threatening food security in regions dependent on grain imports. As Ukraine rebuilds its agricultural sector, it will need to move away from rainfed agricultural practices and incorporate climate change adaptation measures. Irrigation systems will need to expand and be modernized, particularly in southern, eastern and central Ukraine. Local surface and groundwater resources can supply sustainable irrigation options for millions of hectares of cropland even with a projected 3°C warming.
See Rosa et al.
Image: Slavica/iStock / Getty Images Plus/Getty. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Food/2_3.png,MAC_Bench/Nature/Cover/Nature Food/2_3.png,ave_0,2_3.txt,MAC_Bench/Nature/Cover/Nature Food/4_9.png,MAC_Bench/Nature/Cover/Nature Food/4_9.png,clip,4_9.txt,MAC_Bench/Nature/Cover/Nature Food/2_2.png,MAC_Bench/Nature/Cover/Nature Food/2_2.png,vitg,2_2.txt,MAC_Bench/Nature/Cover/Nature Food/5_5.png,MAC_Bench/Nature/Cover/Nature Food/5_5.png,groundtruth,5_5.txt,train
Cell Metabolism,36_7,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Metabolism, Li et al. reveal that sick neurons release lipids to the glia, causing lipid droplet accumulation
and neuroinflammation. The artwork, inspired by Van Gogh's Starry Night, depicts a brain with lipid droplets. Artwork by Melody Hui.",C,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,clip,37_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/12_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/12_3.png,vith,12_3.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_7.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_7.png,groundtruth,36_7.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png,ave_2,36_10.txt,test
ACS Chemical Neuroscience,2024_15,Which of the following options best describe the cover story?,"Cryo-section of one hemisphere from 18-month-old Alzheimer's disease pathology mouse model APP23 stained with two conformation-sensitive amyloid dyes, qFTAA and hFTAA: The dyes are used to visualize structural differences in amyloid depositions in several mouse models. The inset shows single plaques (artistic rendering of confocal fluorescence micrographs).",B,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2018_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2018_6.png,clip,2018_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_15.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_15.png,groundtruth,2024_15.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,vitg,2022_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_18.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_18.png,vith,2021_18.txt,test
BDJ,237_4,Which of the following options best describe the cover story?,"In this issue
This issue features articles on large language models, hyposalivation, and environmental sustainability.

Cover image: From 2018. The cover of this issue combines an acknowledgment of the original World War One commemoration series with a montage and positions the 2018 Armistice cover at 11 o’clock, the traditional placement for the leaf on commemorative poppies, to mark the eleventh hour, day and month of the end of the War.
©Tim Marrs, incorporating original artwork by Philip Bannister",A,MAC_Bench/Nature/Cover/BDJ/237_4.png,MAC_Bench/Nature/Cover/BDJ/237_4.png,groundtruth,237_4.txt,MAC_Bench/Nature/Cover/BDJ/233_6.png,MAC_Bench/Nature/Cover/BDJ/233_6.png,clip,233_6.txt,MAC_Bench/Nature/Cover/BDJ/229_10.png,MAC_Bench/Nature/Cover/BDJ/229_10.png,vith,229_10.txt,MAC_Bench/Nature/Cover/BDJ/232_2.png,MAC_Bench/Nature/Cover/BDJ/232_2.png,vitg,232_2.txt,val
ACS Catalysis,2024_11,Which of the following options best describe the cover story?,The surface curvature of mildly oxidized multi-walled carbon nanotubes impacts the oxygen reduction performance activity toward H2O2 synthesis.,A,MAC_Bench/ACS/Cover/ACS Catalysis/2024_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2015_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2015_11.png,vitg,2015_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2022_21.png,MAC_Bench/ACS/Cover/ACS Catalysis/2022_21.png,clip,2022_21.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2021_3.png,MAC_Bench/ACS/Cover/ACS Catalysis/2021_3.png,vith,2021_3.txt,val
Nature Chemical Engineering,2_1,Which of the following options best describe the cover story?,"Nanoisland nests for cluster catalysis
Stabilizing noble metal cluster catalysts presents a formidable roadblock to harnessing their high atom efficiency and size-dependent properties for industrial reactions. Now, Bruce Gates, Jingyue Liu, Xu Li, Jie Zeng and co-workers report on a strategy for confining few-atom platinum clusters on cerium oxide (CeOx) nanoislands that are stably dispersed on a commercial high-area porous silica support. These ensembles work as nanoreactors, wherein the platinum clusters remain confined even under harsh hydrogenation reaction conditions. The cover image shows an illustrative render of these nanoreactors, with the platinum clusters confined to isolated nanoisland nests.
See Chen et al.
Image: Yizhen Chen, University of California, Davis, and Xu Li, University of Electronic Science and Technology of China. Cover design: Laoise Mac Gabhann.",D,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_1.png,vith,1_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,vitg,1_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,clip,1_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/2_1.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/2_1.png,groundtruth,2_1.txt,train
Nature Mental Health,2_4,Which of the following options best describe the cover story?,"Translational science in mental health research
In our September issue, we publish new work and commentary that feature translational science. As a nod to the translational role that bridges work from animal models to clinical research, the cover displays the profiles of a mouse and a human head in a contiguous line drawing. It symbolizes the interconnectedness of clinical and animal work in mental health research, in which so much is dependent on what can be observed and demonstrated preclinically before it can be translated in humans.
Read more about the enduring importance of translational work in mental health research in our Editorial.
Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_4.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_4.png,groundtruth,2_4.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,vitg,2_6.txt,train
Nature Metabolism,6_5,Which of the following options best describe the cover story?,"Focus on diet and cardiometabolic health
In this Focus issue, we highlight content on how dietary interventions can impact cardiometabolic health, from preclinical models to human studies. The cover image is an artistic representation reflecting the impact of diet on metabolic processes.
An accompanying web collection can be found here: [https://www.nature.com/collections/ddeacfbgfh]
Image: Thomas Phillips. Cover design: Thomas Phillips",B,MAC_Bench/Nature/Cover/Nature Metabolism/2_1.png,MAC_Bench/Nature/Cover/Nature Metabolism/2_1.png,ave_2,2_1.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_5.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_5.png,groundtruth,6_5.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_9.png,clip,6_9.txt,MAC_Bench/Nature/Cover/Nature Metabolism/2_10.png,MAC_Bench/Nature/Cover/Nature Metabolism/2_10.png,vitg,2_10.txt,train
Nature Nanotechnology,19_5,Which of the following options best describe the cover story?,"Pinpoint doping for polymers
The cover shows an atomic force microscopy image of nanoscale doped plastic polymers achieved through precise electrochemical ion implantation.
See Lanyi Xiang et al.
Image: Chong-an Di, Institute of Chemistry, Chinese Academy of Sciences. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Nanotechnology/17_3.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/17_3.png,vitg,17_3.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_5.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_5.png,groundtruth,19_5.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_4.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_4.png,vith,18_4.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,train
Industrial & Engineering Chemistry Research,2024_25,Which of the following options best describe the cover story?,This study proposes a ranking framework by introducing Biochar Quality Index scores based on selected quality parameters and application thereof for adsorptive removal of antibiotic sulfamethoxazole from water matrices.,C,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_23.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_23.png,vith,2022_23.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_44.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_44.png,vitg,2022_44.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_25.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_25.png,groundtruth,2024_25.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_12.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_12.png,clip,2020_12.txt,train
Trends in Microbiology,32_6,Which of the following options best describe the cover story?,"Bacteria can use chemotaxis to locate and establish ecological
partnerships with other organisms. Previously, it has been estimated that some cells
are
too small to be sensed by chemotactic bacteria. However, as discussed in this issue’s
Opinion piece by Seymour et al., recent evidence points to unsuspected chemotactic
precision and indicates that chemotaxis might underpin ecological interactions between
individual bacterial cells. The cover image highlights how chemotactic bacteria (blue
cells)
may use chemical signals to increase time spent in the proximity of other small bacteria
(green cells) or cluster around larger microbes (e.g. phytoplankton). Image courtesy:
Glynn Gorick, Justin Seymour, Douglas Brumley, Roman Stocker, Jean-Baptiste Rain.",C,MAC_Bench/Cell/Cover/Trends in Microbiology/31_9.png,MAC_Bench/Cell/Cover/Trends in Microbiology/31_9.png,vith,31_9.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/24_1.png,MAC_Bench/Cell/Cover/Trends in Microbiology/24_1.png,clip,24_1.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_6.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_6.png,groundtruth,32_6.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/21_6.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_6.png,vitg,21_6.txt,test
Trends in Immunology,45_5,Which of the following options best describe the cover story?,"Tuberculosis is a leading cause of mortality from an infectious disease. On
pages 649–661, Suliman and colleagues discuss new scientific evidence suggesting that
viral infections may contribute to tuberculosis progression and risk. In the illustration,
the
artist was inspired by Mark Rothko, and drew a clump of Mycobacterium tuberculosis
meeting at the center with a swarm of HIV-1. Image credit: Caroline Cha.",B,MAC_Bench/Cell/Cover/Trends in Immunology/40_8.png,MAC_Bench/Cell/Cover/Trends in Immunology/40_8.png,vitg,40_8.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_5.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_5.png,groundtruth,45_5.txt,MAC_Bench/Cell/Cover/Trends in Immunology/42_8.png,MAC_Bench/Cell/Cover/Trends in Immunology/42_8.png,vith,42_8.txt,MAC_Bench/Cell/Cover/Trends in Immunology/35_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/35_3.png,clip,35_3.txt,train
Trends in Plant Science,30_2,Which of the following options best describe the cover story?,"To resist biotic attacks, plants have evolved a sophisticated immune
system with cell-surface immune receptors acting as the first line of the defense
machinery. These receptors are either receptor-like kinases (RLKs) or receptor-like
proteins (RLPs). RLPs lack a cytoplasmic kinase domain for downstream immune
signalling, and leucine-rich repeat (LRR)-containing RLPs constitutively associate
with
the RLK SOBIR1. The RLP/SOBIR1 complex was proposed to be the bimolecular
equivalent of genuine RLK receptors, but it appears that their molecular mechanisms
of
immunity show some striking differences. Wen R.H. Huang and Matthieu H.A.J. Joosten
summarize these differences, focussing on how these receptors recruit the BAK1 co-receptor
and elaborating on the negative crosstalk occurring between the two signalling
networks. The mirror symbolizes the complex relationship between RLPs and RLKs,
illustrating their structural similarities yet functional differences in immune responses.
Image credit: Alison Zou.",A,MAC_Bench/Cell/Cover/Trends in Plant Science/30_2.png,MAC_Bench/Cell/Cover/Trends in Plant Science/30_2.png,groundtruth,30_2.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/27_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/27_1.png,vitg,27_1.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/24_6.png,MAC_Bench/Cell/Cover/Trends in Plant Science/24_6.png,clip,24_6.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/30_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/30_1.png,vith,30_1.txt,train
NATURE GENETICS,56_5,Which of the following options best describe the cover story?,"On the road to ruminant T2T genomics
The ruminant telomere-to-telomere (RT2T) consortium aims to generate complete diploid assemblies for many ruminant species to examine chromosomal evolution in the context of natural selection and domestication.
See Kalbfleisch et al.
Image: Westend61/ Westend61/Getty. Cover design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/NATURE GENETICS/56_5.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_5.png,groundtruth,56_5.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/54_4.png,MAC_Bench/Nature/Cover/NATURE GENETICS/54_4.png,ave_1,54_4.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/52_3.png,MAC_Bench/Nature/Cover/NATURE GENETICS/52_3.png,clip,52_3.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_10.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_10.png,vith,49_10.txt,test
Accounts of Chemical Research,2024_3,Which of the following options best describe the cover story?,M(ImPhen)3,D,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2013_11.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2013_11.png,vitg,2013_11.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_7.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_7.png,clip,2021_7.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_4.png,vith,2014_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_3.png,groundtruth,2024_3.txt,test
The Journal of Organic Chemistry,2025_5,Which of the following options best describe the cover story?,Advancements in loop cyclization approaches for enhanced peptide therapeutics for targeting protein,A,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_5.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2017_2.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2017_2.png,vith,2017_2.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2016_18.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2016_18.png,vitg,2016_18.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2017_23.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2017_23.png,clip,2017_23.txt,test
Organic Letters,2025_5,Which of the following options best describe the cover story?,"The cover picture inspired by the Lantern Festival in China. Cyclopropenone and allyl alcohol/olefin are like fireworks, while radicals are like fuses. Their combination and collision can produce",C,MAC_Bench/ACS/Cover/Organic Letters/2025_3.png,MAC_Bench/ACS/Cover/Organic Letters/2025_3.png,clip,2025_3.txt,MAC_Bench/ACS/Cover/Organic Letters/2023_47.png,MAC_Bench/ACS/Cover/Organic Letters/2023_47.png,ave_2,2023_47.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_5.png,MAC_Bench/ACS/Cover/Organic Letters/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_2.png,MAC_Bench/ACS/Cover/Organic Letters/2025_2.png,ave_3,2025_2.txt,train
ACS Food Science & Technology,2024_5,Which of the following options best describe the cover story?,"–liquid microextraction combined with the solidification of the aqueous phase. This method provides a reliable, sensitive, user-friendly, and eco-friendly alternative for detecting acrylamide levels in vegetable and fruit chips. The graphic was designed with the use of Microsoft Copilot.",A,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_5.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,ave_1,2023_2.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,ave_2,2023_1.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,clip,2022_11.txt,test
Science Signaling,2007_389,Which of the following options best describe the cover story?,"COVER This week features a Protocol on detecting protein interactions with capture beads and flow cytometry. [Image: Christopher Bickel, AAAS]",D,MAC_Bench/Science/Cover/Science Signaling/1_46.png,MAC_Bench/Science/Cover/Science Signaling/1_46.png,vitg,1_46.txt,MAC_Bench/Science/Cover/Science Signaling/8_366.png,MAC_Bench/Science/Cover/Science Signaling/8_366.png,vith,8_366.txt,MAC_Bench/Science/Cover/Science Signaling/1_48.png,MAC_Bench/Science/Cover/Science Signaling/1_48.png,clip,1_48.txt,MAC_Bench/Science/Cover/Science Signaling/2007_389.png,MAC_Bench/Science/Cover/Science Signaling/2007_389.png,groundtruth,2007_389.txt,val
Science,387_6731,Which of the following options best describe the cover story?,"COVER Interwoven granular building blocks form crystallographic networks that are interlinked but not rigidly connected. A range of designs, based on rings or cages, can be made using additive manufacturing. Under stress, the networks show responses that are only partially like a liquid or a solid. This motif has similarities to chain mail used by medieval soldiers and has more recently inspired artist and creator communities. See pages 250 and 269.
Illustration: N. Burgess/Science; Data: W. Zhou et al., Science 387, 269 (2025).",C,MAC_Bench/Science/Cover/Science/376_6590.png,MAC_Bench/Science/Cover/Science/376_6590.png,ave_2,376_6590.txt,MAC_Bench/Science/Cover/Science/338_6109.png,MAC_Bench/Science/Cover/Science/338_6109.png,vith,338_6109.txt,MAC_Bench/Science/Cover/Science/387_6731.png,MAC_Bench/Science/Cover/Science/387_6731.png,groundtruth,387_6731.txt,MAC_Bench/Science/Cover/Science/358_6366.png,MAC_Bench/Science/Cover/Science/358_6366.png,clip,358_6366.txt,train
Molecular Therapy,32_2,Which of the following options best describe the cover story?,"On the cover:Xi et al. demonstrated that intratracheal adeno-associated viral (AAV, green) delivery of a
CasRx-based RNA editing tool induces regeneration of alveolar type II cells (red)
and antagonism of lung fibrosis. Image credit: Shengxi Shen.",D,MAC_Bench/Cell/Cover/Molecular Therapy/30_16.png,MAC_Bench/Cell/Cover/Molecular Therapy/30_16.png,vitg,30_16.txt,MAC_Bench/Cell/Cover/Molecular Therapy/27_7.png,MAC_Bench/Cell/Cover/Molecular Therapy/27_7.png,clip,27_7.txt,MAC_Bench/Cell/Cover/Molecular Therapy/26_5.png,MAC_Bench/Cell/Cover/Molecular Therapy/26_5.png,vith,26_5.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_2.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_2.png,groundtruth,32_2.txt,train
ACS Organic & Inorganic Au,2023_6,Which of the following options best describe the cover story?,"Convex-shaped Hammett plots allow to parametrize organic reactions and select the best catalysts for transformations with wide substrate scope, covering from electron-donor (ED) to electron-withdrawing functional groups (EWG).",B,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,groundtruth,2023_6.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,ave_3,2023_1.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,vith,2023_5.txt,train
Science Signaling,2007_377,Which of the following options best describe the cover story?,"COVER This week features a Perspective on focal adhesions, protein complexes that link the cell interior to the extracellular matrix. The image illustrates a model of focal adhesion proteins functioning as a molecular clutch. [Image: Yu-Li Wang, University of Massachusetts Medical School]",D,MAC_Bench/Science/Cover/Science Signaling/2_63.png,MAC_Bench/Science/Cover/Science Signaling/2_63.png,vith,2_63.txt,MAC_Bench/Science/Cover/Science Signaling/11_530.png,MAC_Bench/Science/Cover/Science Signaling/11_530.png,clip,11_530.txt,MAC_Bench/Science/Cover/Science Signaling/8_366.png,MAC_Bench/Science/Cover/Science Signaling/8_366.png,vitg,8_366.txt,MAC_Bench/Science/Cover/Science Signaling/2007_377.png,MAC_Bench/Science/Cover/Science Signaling/2007_377.png,groundtruth,2007_377.txt,train
Journal of the American Chemical Society,2024_6,Which of the following options best describe the cover story?,"This paper describes the synthesis of atomically isolated Pd sites onto Cu nanoflakes to regulate the protonation of key intermediates. The Pd sites with moderate water activation capability are found to enhance the protonation of *CO at the neighboring Cu site to *COH, which is confirmed to be the rate-determining step through kinetic isotope effect studies. View the article.",A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_6.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_41.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_41.png,clip,2018_41.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_47.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_47.png,ave_1,2017_47.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_29.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_29.png,vith,2011_29.txt,train
ACS Applied Electronic Materials,2025_3,Which of the following options best describe the cover story?,"This illustration depicts a thermoelectric device designed to convert thermal energy gradients into electricity. Highlighted is the nanocomposition nature of the material, that employs CuFeS2, FeS2, and Cu2S sulfide-based materials. The images were enhanced using AI assistance from ChatGPT.",A,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_3.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_4.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_4.png,vith,2025_4.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2019_10.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2019_10.png,clip,2019_10.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2021_6.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2021_6.png,ave_2,2021_6.txt,train
NATURE REVIEWS MICROBIOLOGY,22_4,Which of the following options best describe the cover story?,"Microbial food spoilage, inspired by the Review on p528.
Cover design: Amie Fernandez",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_8.png,ave_2,14_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_11.png,vitg,14_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_4.png,groundtruth,22_4.txt,train
Structure,32_6,Which of the following options best describe the cover story?,"On the cover: The immune receptors and ligands within the Nectin/Necl co-receptor
axis are promising targets for tumor immunotherapy. Hu et al. determined the Nectin-2-bound PVRIG structure and provide insights into the affinity-dependent
intra-axis immunoregulatory mechanism. The cover symbolizes the race between four
immune receptors depicted as Chinese dragons for their ligand, Nectin-2, the dragon
ball. The inhibitory receptor PVRIG (blue dragon) with a higher affinity catches the
ligand, while the activating receptor DNAM-1 (red dragon) awaits its chance. Cover
art credit: Han Wang.",B,MAC_Bench/Cell/Cover/Structure/21_2.png,MAC_Bench/Cell/Cover/Structure/21_2.png,vitg,21_2.txt,MAC_Bench/Cell/Cover/Structure/32_6.png,MAC_Bench/Cell/Cover/Structure/32_6.png,groundtruth,32_6.txt,MAC_Bench/Cell/Cover/Structure/24_10.png,MAC_Bench/Cell/Cover/Structure/24_10.png,clip,24_10.txt,MAC_Bench/Cell/Cover/Structure/20_9.png,MAC_Bench/Cell/Cover/Structure/20_9.png,vith,20_9.txt,train
Trends in Pharmacological Sciences,45_1,Which of the following options best describe the cover story?,"This issue showcases recent advancements in vaccine research. It
underscores the growing application of nucleic acid, recombinant protein, and multi-epitope
peptide subunit vaccines, as well as lipid nanoparticle and dendritic cell-based
platforms in the design and delivery of vaccines. These innovative approaches are
proving effective against a range of diseases, including infectious viral diseases
like mpox
and enterovirus, parasitic infections such as malaria, and various cancers, all of
which
necessitate a multifaceted immune response. The inclusion of adjuvants, which enhance
vaccine efficacy by stimulating innate immune receptors like Toll-like receptors (TLRs),
is
crucial for achieving optimal results. The cover image features various vaccine types
in the
background while spotlighting a new generation of small molecule (SM) adjuvants, made
possible through advancements in high-throughput screening technologies. In contrast
to
traditional adjuvants, which are often large and complex molecules (lower left), innovative
SM agonists like 2B182C for TLR4 (depicted in red on the cell surface) are prominently
featured. Additionally, PVP-057 and 1V270, which target key endosomal innate immune
receptors—the double stranded RNA sensor TLR3 (shown in blue) and the single stranded
RNA sensor TLR7 (illustrated in green), respectively—are also represented. The cover
image
was designed by Wolfgang W. Leitner and created by Lisa A. Leitner using Adobe Illustrator.",A,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_1.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_1.png,groundtruth,45_1.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,vitg,34_8.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_12.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_12.png,vith,40_12.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/35_4.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/35_4.png,clip,35_4.txt,train
Matter,7_11,Which of the following options best describe the cover story?,"On the cover: Chirality is a fundamental property of the universe. The cover of this
issue of Matter presents the synthesis of bichiral perovskite nanocrystals by Liu et al. The primary visual elements of the illustration, featuring two types of chiral nanocrystals,
represent mirror-symmetrical matter in the cosmos. Stimulated by high-energy radiation
in the universe, these perovskite nanoscintillators generate photogenerated charge
carriers with opposite spin directions. This introduces a novel concept of chiral
perovskite scintillator materials with promising prospects for innovative materials,
drug delivery systems, and various bioengineering applications.",D,MAC_Bench/Cell/Cover/Matter/1_2.png,MAC_Bench/Cell/Cover/Matter/1_2.png,clip,1_2.txt,MAC_Bench/Cell/Cover/Matter/2_5.png,MAC_Bench/Cell/Cover/Matter/2_5.png,vitg,2_5.txt,MAC_Bench/Cell/Cover/Matter/1_6.png,MAC_Bench/Cell/Cover/Matter/1_6.png,vith,1_6.txt,MAC_Bench/Cell/Cover/Matter/7_11.png,MAC_Bench/Cell/Cover/Matter/7_11.png,groundtruth,7_11.txt,train
Nature Cell Biology,26_7,Which of the following options best describe the cover story?,"RNA binding in glioblastoma
The authors show that the RNA–RNA-binding protein complex LOC–DHX15 drives microglia infiltration into the tumour microenvironment in glioblastoma.
See Wu, Zhao, Shin & Yin et al.
Image: Wu Lele, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Cell Biology/9_1.png,MAC_Bench/Nature/Cover/Nature Cell Biology/9_1.png,vitg,9_1.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_7.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_7.png,groundtruth,26_7.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/19_7.png,MAC_Bench/Nature/Cover/Nature Cell Biology/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/25_1.png,MAC_Bench/Nature/Cover/Nature Cell Biology/25_1.png,clip,25_1.txt,val
Nature Human Behaviour,8_1,Which of the following options best describe the cover story?,"Executive function delays in neurodevelopmental conditions
Executive function delays are common in childhood neurodevelopmental conditions, such as autism, attention deficit hyperactivity disorder and tic disorders. However, it has been unclear whether delays in executive function development are a transdiagnostic feature of these conditions. Sadozai and colleagues address this question through a systematic review and meta-analysis of 180 studies. They find that, although there are a few differences among conditions, executive function delays are a transdiagnostic marker for neurodevelopmental conditions.
See Sadozai et al.
Image: Chris Sheng from Heifei Sondii Media Technology Co., Ltd. Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_1.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_1.png,groundtruth,8_1.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_3.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_3.png,vitg,7_3.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_4.png,clip,5_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,vith,8_2.txt,train
Science Robotics,9_89,Which of the following options best describe the cover story?,"ONLINE COVER Special Issue on Legged Robots. Developing legged robots capable of complex motor skills is a major challenge for roboticists. Haarnoja et al. used deep reinforcement learning to train miniature humanoid robots, Robotis OP3, to play a game of one-versus-one soccer. The robots were capable of exhibiting not only agile movements, such as walking, kicking the ball, and rapid recovery from falls, but also emergent behaviors to adapt to the game scenario, such as subtle defensive moves and dynamic footwork in response to the opponent. This month’s cover is an image of the miniature humanoid robot kicking a ball. Credit: Google DeepMind",D,MAC_Bench/Science/Cover/Science Robotics/2_6.png,MAC_Bench/Science/Cover/Science Robotics/2_6.png,vith,2_6.txt,MAC_Bench/Science/Cover/Science Robotics/5_49.png,MAC_Bench/Science/Cover/Science Robotics/5_49.png,clip,5_49.txt,MAC_Bench/Science/Cover/Science Robotics/5_40.png,MAC_Bench/Science/Cover/Science Robotics/5_40.png,vitg,5_40.txt,MAC_Bench/Science/Cover/Science Robotics/9_89.png,MAC_Bench/Science/Cover/Science Robotics/9_89.png,groundtruth,9_89.txt,train
Nature Microbiology,9_5,Which of the following options best describe the cover story?,"Focus on microbial ecology
Microbes and viruses are abundant across terrestrial, freshwater and marine systems, and their behaviours have a profound influence on biogeochemical cycling, the climate, plant and agricultural productivity, and human and animal health. However, our understanding is plagued by unknowns regarding the nature of microbial interactions, the evolution and diversity of these communities, and best practices for studying and conceptualizing the complex dynamics of this unseen majority. This month’s focus issue features a set of Reviews, Perspectives and commentary that span microbial ecology from the organismal to the global scales, shining a light on the research questions that will guide the field.
See Editorial
Image and cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/Nature Microbiology/8_1.png,MAC_Bench/Nature/Cover/Nature Microbiology/8_1.png,clip,8_1.txt,MAC_Bench/Nature/Cover/Nature Microbiology/6_8.png,MAC_Bench/Nature/Cover/Nature Microbiology/6_8.png,ave_2,6_8.txt,MAC_Bench/Nature/Cover/Nature Microbiology/8_3.png,MAC_Bench/Nature/Cover/Nature Microbiology/8_3.png,ave_3,8_3.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_5.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_5.png,groundtruth,9_5.txt,train
innovation,6_1,Which of the following options best describe the cover story?,"On the cover: Wind, the movement of air, plays a vital role in influencing the Earth’s climate.
Moreover, wind energy is a form of renewable energy that harnesses the power of the
wind to generate electricity, serving as a cornerstone of the global energy transition.
As humanity increasingly turns to wind energy for a sustainable future, understanding
the factors shaping wind patterns has become more urgent than ever. While volcanic
eruptions are well known for their cooling effects and impacts on rainfall, their
influence on wind has largely gone unnoticed—until now. A study by Shen et al. reveals how the largest eruptions of the past millennium caused a significant, albeit
temporary, slowdown in global near-surface winds, particularly in subtropical regions.
Volcanic aerosols can disrupt wind energy systems, posing challenges to the resilience
of renewable energy. As the world races toward a carbon-neutral future, these findings
highlight an overlooked climate risk, urging us to consider the delicate effect from
natural forces on renewable energy systems.",A,MAC_Bench/Cell/Cover/innovation/6_1.png,MAC_Bench/Cell/Cover/innovation/6_1.png,groundtruth,6_1.txt,MAC_Bench/Cell/Cover/innovation/6_2.png,MAC_Bench/Cell/Cover/innovation/6_2.png,clip,6_2.txt,MAC_Bench/Cell/Cover/innovation/3_1.png,MAC_Bench/Cell/Cover/innovation/3_1.png,ave_2,3_1.txt,MAC_Bench/Cell/Cover/innovation/4_1.png,MAC_Bench/Cell/Cover/innovation/4_1.png,ave_3,4_1.txt,train
CELL RESEARCH,34_7,Which of the following options best describe the cover story?,"A Nian beast (proinflammatory PD-1+ T cells) wreaks havoc in the village (a metaphor for atherosclerosis, AS) on New Year's Eve. A man, dressed in red, ignites firecrackers (FcgR-binding anti-PD-1 mAb), preventing the Nian beast from causing trouble in the village (the shrinkage of AS plaques). See page 407–427 by Lin Fan et al. for details.",D,MAC_Bench/Nature/Cover/CELL RESEARCH/34_9.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_9.png,vitg,34_9.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_8.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_8.png,ave_2,32_8.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/31_3.png,MAC_Bench/Nature/Cover/CELL RESEARCH/31_3.png,clip,31_3.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png,groundtruth,34_7.txt,val
Nature Biomedical Engineering,8_10,Which of the following options best describe the cover story?,"Multi-pass flow cytometry via laser-light barcodes
This issue highlights a high-throughput method for the rapid discovery of high-affinity antibodies, the large-scale mass-spectrometric quantification of glycopeptides in plasma, an assay for the identification, sorting and profiling of killer cells, high-throughput microfluidics for the identification of druggable regulators of cell secretion, the prediction of interactions between drugs and intestinal drug transporters, the high-throughput identification of genetic and cellular drivers of syncytium formation induced by SARS-CoV-2, multi-pass flow cytometry for measuring single-cell dynamics, and an assay for sensing the DNA-mismatch tolerance of Cas9.
The cover illustrates that barcoding cells with microparticles that emit near-infrared laser light allows for multi-pass flow cytometry with more markers and fewer colours.
See Kwok et al.
Image: LASE Innovation. Cover design: Alex Wing.",D,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_2.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_2.png,clip,5_2.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_6.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_6.png,vith,7_6.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_11.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_11.png,vitg,8_11.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_10.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_10.png,groundtruth,8_10.txt,test
Accounts of Materials Research,2024_10,Which of the following options best describe the cover story?,"The cover picture illustrates the preparation of diamond composites using ancient Chinese alchemy techniques, reflecting the synergistic effect when diamond is composited with other materials.",D,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_11.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_11.png,clip,2021_11.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_9.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_9.png,ave_0,2021_9.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_11.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_11.png,vitg,2024_11.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_10.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_10.png,groundtruth,2024_10.txt,train
ACS Macro Letters,2024_8,Which of the following options best describe the cover story?,"Poly(methylvinyl siloxane) (PMVS) with a cysteine derivative side chain designated PMVS-Cys was prepared using anionic polymerization and an ene-thiol reaction. PMVS-Cys forms a preferred-handed helical conformation in both solution and film via hydrogen bonding. The helical structure remains during the calcination process, resulting in a silica with a helical structure.",C,MAC_Bench/ACS/Cover/ACS Macro Letters/2017_9.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2017_9.png,clip,2017_9.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2019_1.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2019_1.png,vith,2019_1.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_8.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2015_3.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2015_3.png,vitg,2015_3.txt,train
ACS Central Science,2024_6,Which of the following options best describe the cover story?,"Enzyme engineering requires researchers to navigate a high-dimensional sequence–activity landscape to identify variants with the desired properties. This represents a highly challenging task, but machine learning and automation can accelerate such projects and increase the chances of success.",B,MAC_Bench/ACS/Cover/ACS Central Science/2024_8.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_8.png,ave_1,2024_8.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_6.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_1.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_1.png,vith,2024_1.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_2.png,clip,2023_2.txt,test
Joule,8_1,Which of the following options best describe the cover story?,"On the cover: The cover image depicts AI as becoming critical to overcome the rapidly
widening gap between the existing computational capabilities and the evolving needs
of the electric power industry to cope with the massively increasing complexity and
uncertainty in the electric grid amidst the transition to a low-carbon energy future.
In this issue of Joule, Hamann et al. show how emerging AI foundation models are an ideal technology platform to collaborate
across the sector in a moonshot to harness emerging AI capabilities, which will enable
much more computationally efficient models, by orders of magnitude, for planning,
managing, and controlling the electric grid while providing high performance, adaptability,
and scalability. Artist/source: Lara Karadogan, IBM Research (lara.karadogan@ibm.com).",D,MAC_Bench/Cell/Cover/Joule/7_7.png,MAC_Bench/Cell/Cover/Joule/7_7.png,vitg,7_7.txt,MAC_Bench/Cell/Cover/Joule/8_3.png,MAC_Bench/Cell/Cover/Joule/8_3.png,ave_1,8_3.txt,MAC_Bench/Cell/Cover/Joule/5_3.png,MAC_Bench/Cell/Cover/Joule/5_3.png,clip,5_3.txt,MAC_Bench/Cell/Cover/Joule/8_1.png,MAC_Bench/Cell/Cover/Joule/8_1.png,groundtruth,8_1.txt,train
One Earth,8_1,Which of the following options best describe the cover story?,"On the cover: Mangroves are crucial carbon sinks, yet these vital ecosystems are being
lost at an alarming rate. The primary driver of this decline is aquaculture, particularly
the conversion of mangrove forests into shrimp farms. In this month's issue, Yufeng
Jiang and colleagues show that 60% of China and Southeast Asia's lost mangroves can
be feasibly restored, with substantial ecological benefits. Cover image: Getty, Suriyapong
Thongsawang.",D,MAC_Bench/Cell/Cover/One Earth/5_4.png,MAC_Bench/Cell/Cover/One Earth/5_4.png,ave_3,5_4.txt,MAC_Bench/Cell/Cover/One Earth/5_8.png,MAC_Bench/Cell/Cover/One Earth/5_8.png,clip,5_8.txt,MAC_Bench/Cell/Cover/One Earth/2_4.png,MAC_Bench/Cell/Cover/One Earth/2_4.png,ave_1,2_4.txt,MAC_Bench/Cell/Cover/One Earth/8_1.png,MAC_Bench/Cell/Cover/One Earth/8_1.png,groundtruth,8_1.txt,test
Nature Cardiovascular Research,3_5,Which of the following options best describe the cover story?,"Regenerative senescence in cardiac repair
Zhang et al. show that the transcription factor Egr1 regulates transient senescence in cardiac fibroblasts during neonatal heart regeneration and upon agrin-mediated cardiac repair in adult mice, acting downstream of the integrin–FAK–ERK1/2–Akt1 axis.
See Zhang et al.
Image: Genia Brodsky, Design Section, Weizmann Institute of Science. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_9.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_9.png,clip,3_9.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,vith,1_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_5.png,groundtruth,3_5.txt,val
Accounts of Chemical Research,2025_3,Which of the following options best describe the cover story?,With the advantage of the design,A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_14.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_14.png,vith,2021_14.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2023_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2023_4.png,clip,2023_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_15.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_15.png,vitg,2024_15.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_5,Which of the following options best describe the cover story?,"Artificial intelligence in liver cancer, inspired by the Perspective on p585.
Cover design: Laura Marshall",A,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_5.png,groundtruth,21_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_3.png,clip,20_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,vitg,20_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_12.png,ave_1,20_12.txt,train
Science Signaling,2007_396,Which of the following options best describe the cover story?,"COVER This week features a Perspective on Dictyostelium chemotaxis. The image shows the various ways that movement can be controlled during Dictyostelium migration. [Image: Christopher Bickel, AAAS]",D,MAC_Bench/Science/Cover/Science Signaling/11_546.png,MAC_Bench/Science/Cover/Science Signaling/11_546.png,clip,11_546.txt,MAC_Bench/Science/Cover/Science Signaling/2_61.png,MAC_Bench/Science/Cover/Science Signaling/2_61.png,vitg,2_61.txt,MAC_Bench/Science/Cover/Science Signaling/4_200.png,MAC_Bench/Science/Cover/Science Signaling/4_200.png,vith,4_200.txt,MAC_Bench/Science/Cover/Science Signaling/2007_396.png,MAC_Bench/Science/Cover/Science Signaling/2007_396.png,groundtruth,2007_396.txt,train
Cell Reports Methods,4_11,Which of the following options best describe the cover story?,"On the cover: In this issue, Nimpf et al. establish in vivo two-photon calcium imaging in awake pigeons and use the approach to investigate color
processing in the avian visual cortex. Cover image shows a pattern of birds and eyes.
Courtesy gettyimages/Dusan Stankovic.",C,MAC_Bench/Cell/Cover/Cell Reports Methods/1_2.png,MAC_Bench/Cell/Cover/Cell Reports Methods/1_2.png,vith,1_2.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_10.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_10.png,ave_2,3_10.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_11.png,groundtruth,4_11.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_1.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_1.png,clip,3_1.txt,val
ACS Medicinal Chemistry Letters,2025_2,Which of the following options best describe the cover story?,Preventing the release of the fusion peptide is a challenging approach to target influenza A virus hemagglutinin. This study explores the putative binding site of the pinanamine-containing compound M090. Computational tools were used to examine the feasibility of the binding mode and the structure–activity relationships. The results open clues for the design of future small-molecule inhibitors targeting hemagglutinin.,C,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_9.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_9.png,ave_3,2017_9.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_4.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_4.png,ave_2,2017_4.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_1.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_1.png,clip,2025_1.txt,train
ACS Applied Materials & Interfaces,2025_5,Which of the following options best describe the cover story?,"A composite film composed of liquid crystal polymer networks and polyvinylidene fluoride doped with carbon nanopowders exhibits a roll angle change of 235° under the midday sun during summer. It demonstrates phototactic and light-avoiding rolling behavior, indicating",D,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_39.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_39.png,clip,2016_39.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2023_19.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2023_19.png,vith,2023_19.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2017_22.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2017_22.png,vitg,2017_22.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_5.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_5.png,groundtruth,2025_5.txt,test
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_1,Which of the following options best describe the cover story?,"‘Growing old’, inspired by this Focus issue on cell senescence. Cell senescence — a state of irreversible cell-growth arrest — has important physiological functions and is a key driver of ageing. The articles in this issue explore the molecular mechanisms that induce cell senescence, functional consequences for surrounding tissues, emerging therapies to counteract senescent-associated diseases, and recommendations for identifying senescent cells.
Cover design: Vicky Summersby",A,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_1.png,groundtruth,25_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_6.png,ave_3,15_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_2.png,ave_2,15_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/20_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/20_6.png,clip,20_6.txt,train
Nature Sustainability,7_12,Which of the following options best describe the cover story?,"Mitigation shortfalls in mining
Sustainable mining relies on vigorous and comprehensive mitigation strategies; however, two studies in this issue show that these measures are falling short. Among artisanal and often illegal mining operations in the Amazon, Fritz et al. demonstrate that while mercury retorts reduce losses, the amount of mercury and CO2 emissions into the environment remains substantial. Globally, Aska et al. draw attention to the number of mine tailing facilities contained within or near the boundaries of protected areas, posing a potential hazard for regional biodiversity.
See Fritz et al. and Aska et al.
Image: Mario Schmidt, Pforzheim University. Cover Design: Alex Whitworth.",A,MAC_Bench/Nature/Cover/Nature Sustainability/7_12.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_12.png,groundtruth,7_12.txt,MAC_Bench/Nature/Cover/Nature Sustainability/1_9.png,MAC_Bench/Nature/Cover/Nature Sustainability/1_9.png,clip,1_9.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_3.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_3.png,ave_2,7_3.txt,MAC_Bench/Nature/Cover/Nature Sustainability/4_2.png,MAC_Bench/Nature/Cover/Nature Sustainability/4_2.png,vith,4_2.txt,train
Nature Reviews Endocrinology,20_3,Which of the following options best describe the cover story?,"The challenges of assessing adiposity, inspired by the Perspective on p615.
Cover design: Edward Byrne",D,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,vitg,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_4.png,vith,17_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_3.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_3.png,groundtruth,20_3.txt,test
Current Biology,34_9,Which of the following options best describe the cover story?,"On the cover: With over 30,000 species worldwide, darkling beetles have diversified
into a variety of ecological niches. They are masters of shape shifting, ranging from
cylindrical, wood-boring forms to hemispherical, surface-grazing forms. In this issue,
Li et al. show that this extraordinary diversity is driven by ancient rapid radiations, frequent
ecological transitions, and rapid bursts of morphological evolution. The cover image
is designed to tell this story, with darkling beetles of various shapes arranged in
a ring to showcase a “big bang” evolution into a spectacular array of ecomorphs that
we see today. In the center is an arboreal pie-dish beetle, part of a large Gondwanan
clade that underwent adaptive radiation. The evolutionary history of darkling beetles
demonstrates a critical role of ecology as a driver of morphological evolution and
is essential to improving our understanding of the general processes that have shaped
the spectacular biological diversity on Earth. Image by Yun “Living” Li.",C,MAC_Bench/Cell/Cover/Current Biology/22_5.png,MAC_Bench/Cell/Cover/Current Biology/22_5.png,vith,22_5.txt,MAC_Bench/Cell/Cover/Current Biology/23_5.png,MAC_Bench/Cell/Cover/Current Biology/23_5.png,clip,23_5.txt,MAC_Bench/Cell/Cover/Current Biology/34_9.png,MAC_Bench/Cell/Cover/Current Biology/34_9.png,groundtruth,34_9.txt,MAC_Bench/Cell/Cover/Current Biology/24_5.png,MAC_Bench/Cell/Cover/Current Biology/24_5.png,ave_3,24_5.txt,train
Trends in Chemistry,6_8,Which of the following options best describe the cover story?,"Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for part 1 showcases the 'great career race' for early-career
scientists today, with key milestones towards promotion and the many paths that can
be taken on the road to success. Each running at their own pace, the authors in this
issue are all aiming to innovate with an impact, solve real-world problems and become
inspiring leaders themselves. Artwork credit: Phillip Krzeminski",A,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,groundtruth,6_8.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,ave_3,6_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,clip,6_7.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,vith,6_6.txt,train
Nature Synthesis,3_8,Which of the following options best describe the cover story?,"Tuning interactions at catalytic sites
A local electronic manipulation strategy is developed for stabilizing high-valence Ru single sites. The materials are efficient bifunctional catalysts for water electrolysis.
See Lu et al.
Image: Shaojun Guo, Peking University. Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,ave_0,3_9.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,clip,2_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_8.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_8.png,groundtruth,3_8.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,vitg,1_8.txt,train
Nature Catalysis,7_6,Which of the following options best describe the cover story?,"Active sites revealed
In their work, the authors present a methodology to map the active sites of nanoparticle catalysts via a combination of atomic electron tomography and first-principles-trained machine learning. This allows them to draw structure–activity relationships and propose a local environment descriptor.
See Yang et al.
Image: Yao Yang, Westlake University. Cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Catalysis/1_10.png,MAC_Bench/Nature/Cover/Nature Catalysis/1_10.png,vitg,1_10.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_6.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_6.png,groundtruth,7_6.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_2.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Catalysis/6_11.png,MAC_Bench/Nature/Cover/Nature Catalysis/6_11.png,vith,6_11.txt,train
ACS Measurement Science Au,2025_1,Which of the following options best describe the cover story?,"This cover highlights the 2024 Rising Stars in Measurement Science. These nineteen early-career scientists from across the globe are making significant contributions to the field of measurement science, in spectroscopy, mass spectrometry, electrochemistry, and separations.",A,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png,clip,2022_2.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,vitg,2022_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2021_1.png,vith,2021_1.txt,test
Trends in Pharmacological Sciences,45_7,Which of the following options best describe the cover story?,"Despite the successes in recent years in the development of novel cancer
therapies including small molecule drugs and biologics, resistance to these therapies
is common and affects disease prognosis and quality of life of patients. Towards
eradication of therapy resistance, clinicians and research scientists in different
parts
of the world have leveraged new, advanced technological tools to gain greater insights
of the molecular underpinnings of cancer progression and resistance to treatment.
These insights promise to revolutionize current approaches including drug combination
strategies in tackling therapy resistance in cancer. The June special issue of Trends in
   Pharmacological Sciences features expert perspectives on the recent developments in
the cancer drug resistance field and exciting future avenues of research. Image credit:
Lucidio Studio Inc. via Getty Images Plus.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/37_3.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/37_3.png,ave_0,37_3.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/36_9.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/36_9.png,vith,36_9.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_7.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_7.png,groundtruth,45_7.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,clip,34_8.txt,val
Macromolecules,2024_24,Which of the following options best describe the cover story?,"Thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) microgels with varying degrees of crosslinking, including ultra-low self-crosslinking, were systematically investigated using a combination of light and X-ray scattering techniques, supported by numerical simulations, across their volume phase transition.",C,MAC_Bench/ACS/Cover/Macromolecules/2016_19.png,MAC_Bench/ACS/Cover/Macromolecules/2016_19.png,vith,2016_19.txt,MAC_Bench/ACS/Cover/Macromolecules/2011_3.png,MAC_Bench/ACS/Cover/Macromolecules/2011_3.png,clip,2011_3.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_24.png,MAC_Bench/ACS/Cover/Macromolecules/2024_24.png,groundtruth,2024_24.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_18.png,MAC_Bench/ACS/Cover/Macromolecules/2010_18.png,vitg,2010_18.txt,train
Environment & Health,2024_10,Which of the following options best describe the cover story?,The cover emphasizes the differential accumulation of thallium in zebrafish embryos and larvae and the multifaceted nature of Tl toxicity in relation to the developmental stages of the aquatic organism.,B,MAC_Bench/ACS/Cover/Environment & Health/2024_2.png,MAC_Bench/ACS/Cover/Environment & Health/2024_2.png,ave_3,2024_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_10.png,MAC_Bench/ACS/Cover/Environment & Health/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/Environment & Health/2023_3.png,MAC_Bench/ACS/Cover/Environment & Health/2023_3.png,ave_2,2023_3.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,clip,2024_7.txt,train
BDJ In Practice,37_2,Which of the following options best describe the cover story?,"In this issue...
Welcome to the first artificial intelligence themed issue of BDJ In Practice!

We're looking at everything from horizon-scanning, future gazing, AI's impact on oral surgery, indemnity ramifications - and more",B,MAC_Bench/Nature/Cover/BDJ In Practice/37_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_8.png,ave_3,37_8.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,groundtruth,37_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_6.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_6.png,clip,35_6.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_7.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_7.png,ave_2,36_7.txt,train
Trends in Cell Biology,35_2,Which of the following options best describe the cover story?,"Organelle communication is a growing research field, and its
impairment is increasingly associated with mechanisms of cellular dysfunction. Recent
studies have shed light on the pivotal role of lipids in inter-organelle communication,
revealing their influence on processes such as organelle membrane fission and
remodeling. In this issue, Domingues et al. explore how lipids mediate inter-organelle
communication. The authors highlight emerging techniques that improve lipid
detection and quantification, paving the way for a systematic understanding of lipid-mediated
intracellular communication. Cover design by Neuza Domingues.",C,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_10.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_10.png,clip,34_10.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_3.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/27_3.png,vitg,27_3.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/35_2.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/35_2.png,groundtruth,35_2.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_9.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_9.png,vith,26_9.txt,train
Nature Biomedical Engineering,8_12,Which of the following options best describe the cover story?,"Modelling latent structures in neural activity to better predict behaviour
This issue highlights computational methods for use in multi-omics microsampling to profile lifestyle-associated changes, for the design of humanized versions of antibodies with improved stability, for the optimization of monoclonal antibodies for reduced self-association and non-specific binding, for the classification of tumour type and the prediction of microsatellite status on the basis of somatic mutations, for describing macroscopic resting-state brain dynamics, and for modelling nonlinear latent factors and structures in the activity of neural populations to enable flexible inference.
The cover illustrates that latent factors and latent structures in the activity of neural populations can be computationally modelled to better predict neural activity and behaviour.
See Abbaspourazad et al.
Image: Ella Marushchenko and Ekaterina Zvorykina (Ella Maru Studio, Inc.). Cover design: Alex Wing.",C,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,vith,7_4.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/3_1.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/3_1.png,clip,3_1.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_12.png,groundtruth,8_12.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_12.png,vitg,5_12.txt,train
NATURE MEDICINE,30_5,Which of the following options best describe the cover story?,"Epigenetics for predicting cancer
In this issue, Widschwendter and colleagues establish that screening of cervical cancer using a DNA methylation-based triage showed better performance than cytology in the detection of prevalent disease and prediction of incident disease. The cover highlights the link between cancer development over time and increasing DNA methylation, which is already present in the absence of visibly abnormal cells.
See Widschwendter et al.
Image: Martin Widschwendter, University of Innsbruck; created by Jagoba Malumbres-Olarte, scientific graphic designer. Cover design: Marina Corral Spence",D,MAC_Bench/Nature/Cover/NATURE MEDICINE/11_12.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/11_12.png,clip,11_12.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/12_8.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/12_8.png,vith,12_8.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/23_1.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/23_1.png,vitg,23_1.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_5.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_5.png,groundtruth,30_5.txt,train
Nature Food,5_8,Which of the following options best describe the cover story?,"Food-borne pathogens and the pig industry
Salmonella enterica is a pathogen that can cause serious food-borne illnesses in humans. As many cases go unreported, the prevalence of infections might be largely underestimated, underscoring the importance of understanding the reasons for the rise of S. enterica. Human activities contribute to the global spread of this pathogen, much of which comes from modernized livestock production systems. Over the past century, the pig industry has contributed to the spread of S. enterica through intensive farming, overuse of antimicrobials leading to the acquisition of resistance genes, and the global pork trade. Pigs are now the main source of transmission of the pathogen to other hosts. Greater emphasis on the surveillance of S. enterica infections in humans and animals is key to prevent future disease outbreaks.
See Li et al.
Image: WLADIMIR BULGAR/SCIENCE PHOTO LIBRARY/ Science Photo Library/Getty. Cover design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/Nature Food/5_8.png,MAC_Bench/Nature/Cover/Nature Food/5_8.png,groundtruth,5_8.txt,MAC_Bench/Nature/Cover/Nature Food/4_1.png,MAC_Bench/Nature/Cover/Nature Food/4_1.png,ave_1,4_1.txt,MAC_Bench/Nature/Cover/Nature Food/3_10.png,MAC_Bench/Nature/Cover/Nature Food/3_10.png,ave_2,3_10.txt,MAC_Bench/Nature/Cover/Nature Food/4_12.png,MAC_Bench/Nature/Cover/Nature Food/4_12.png,clip,4_12.txt,train
Accounts of Materials Research,2024_4,Which of the following options best describe the cover story?,Integration of plasma and materials exemplified through the interaction between the plasma streamer and materials.   View the article.,B,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_9.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_9.png,clip,2021_9.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_4.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_2.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_7.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_7.png,vith,2021_7.txt,test
Trends in Genetics,40_5,Which of the following options best describe the cover story?,"Due to their astonishing phenotypic diversity and amenability to
genetic analysis and functional experimentation, monkeyflowers provide an excellent
platform to probe the molecular mechanisms of phenotypic evolution. In this issue,
Yao-Wu Yuan and colleagues discuss various ""unusual suspects"" for the molecular
basis of phenotypic variation, revealed by recent studies in a wide range of organisms
including monkeyflowers. Illustration by Bianca T. Ferreira.",C,MAC_Bench/Cell/Cover/Trends in Genetics/38_5.png,MAC_Bench/Cell/Cover/Trends in Genetics/38_5.png,vith,38_5.txt,MAC_Bench/Cell/Cover/Trends in Genetics/36_4.png,MAC_Bench/Cell/Cover/Trends in Genetics/36_4.png,vitg,36_4.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_5.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_5.png,groundtruth,40_5.txt,MAC_Bench/Cell/Cover/Trends in Genetics/36_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/36_1.png,clip,36_1.txt,val
Nature Computational Science,4_8,Which of the following options best describe the cover story?,"Semiconductor discovery with data-driven strategies
Computational methods can play a key role in the discovery of semiconductor materials, such as the chips depicted on the cover. In this issue, Lijun Zhang and colleagues highlight data-driven computational frameworks for improving semiconductor discovery and device development, as well as discuss recent advances, challenges and opportunities that lie ahead.
See Zhang et. al.
Image: MirageC/Moment / Getty Images. Cover design: Alex Wing",B,MAC_Bench/Nature/Cover/Nature Computational Science/2_2.png,MAC_Bench/Nature/Cover/Nature Computational Science/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,groundtruth,4_8.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_10.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_10.png,vith,3_10.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_9.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_9.png,ave_3,3_9.txt,train
Cancer Cell,43_1,Which of the following options best describe the cover story?,"On the cover: The cover illustrates how glioblastoma (GBM) aligns its growth with
the brain's daily rhythms. Inspired by artist Sophie Taeuber-Arp and designed by Dr.
Olivia Walch, this visual highlights the daytime tumor growth driven by the circadian
surge in glucocorticoids (green dots). Gonzalez-Aponte et al. discover that blocking circadian regulation of glucocorticoid receptor signaling
slows GBM proliferation in both mouse and human GBM models. Targeting circadian mechanisms
to combat GBM holds great promise and has significant implications for understanding
how the circadian system may influence cancer progression, both within the brain and
beyond.",D,MAC_Bench/Cell/Cover/Cancer Cell/28_4.png,MAC_Bench/Cell/Cover/Cancer Cell/28_4.png,vith,28_4.txt,MAC_Bench/Cell/Cover/Cancer Cell/33_2.png,MAC_Bench/Cell/Cover/Cancer Cell/33_2.png,ave_2,33_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/26_5.png,MAC_Bench/Cell/Cover/Cancer Cell/26_5.png,clip,26_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/43_1.png,MAC_Bench/Cell/Cover/Cancer Cell/43_1.png,groundtruth,43_1.txt,test
Nature Cities,1_6,Which of the following options best describe the cover story?,"Of skies and skylines
How we build and manage our cities affects air, climate and views. In this issue, Anna Zhelnina considers efforts to preserve the iconic skyline of Saint Petersburg, Russia, while Xia et al. document how many cities effectively benefit from the carbon mitigation efforts of other cities connected by supply chains.
See Zhelnina and Xia et al.
Image: Kirill Nikitin/Alamy Stock Photo. Cover design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Cities/1_6.png,MAC_Bench/Nature/Cover/Nature Cities/1_6.png,groundtruth,1_6.txt,MAC_Bench/Nature/Cover/Nature Cities/1_9.png,MAC_Bench/Nature/Cover/Nature Cities/1_9.png,clip,1_9.txt,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,ave_3,1_3.txt,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,ave_2,1_11.txt,train
BDJ,237_10,Which of the following options best describe the cover story?,"In this issue
This issue features articles on composite resin restorations, dental anatomy, and chairside learning.

Cover image: From 2008. The cover for this issue focuses on the dental world of 2008 when a significant development was the beginning of mandatory registration for dental care professionals (DCPs) with the General Dental Council. The ‘featured’ historic cover seen by the right hand of the person in this cover is a SEM, a source of images used from time to time as striking and as a literal representation of science as art; an ongoing connection. Published as Volume 204 No 3 on 9 Feb 2008, little did the world suspect that as the year developed so would a financial crisis, the effects and ramifications of which still have echoes to this day.
©Tim Marrs",D,MAC_Bench/Nature/Cover/BDJ/229_7.png,MAC_Bench/Nature/Cover/BDJ/229_7.png,vitg,229_7.txt,MAC_Bench/Nature/Cover/BDJ/237_5.png,MAC_Bench/Nature/Cover/BDJ/237_5.png,vith,237_5.txt,MAC_Bench/Nature/Cover/BDJ/229_11.png,MAC_Bench/Nature/Cover/BDJ/229_11.png,clip,229_11.txt,MAC_Bench/Nature/Cover/BDJ/237_10.png,MAC_Bench/Nature/Cover/BDJ/237_10.png,groundtruth,237_10.txt,train
Nature Cities,1_9,Which of the following options best describe the cover story?,"Port city pollution
Air pollution from the shipping industry is a problem in coastal cities. This study finds that although small-particulate pollution has fallen in China’s port cities, such as Tianjin (pictured), due to shipping emissions reductions, mortality associated with long-term exposure has risen.
See Luo et al.
Image: DuKai photographer/Moment/Getty. Cover Design: Lauren Heslop.",D,MAC_Bench/Nature/Cover/Nature Cities/1_1.png,MAC_Bench/Nature/Cover/Nature Cities/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Cities/2_1.png,MAC_Bench/Nature/Cover/Nature Cities/2_1.png,ave_3,2_1.txt,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,vith,1_5.txt,MAC_Bench/Nature/Cover/Nature Cities/1_9.png,MAC_Bench/Nature/Cover/Nature Cities/1_9.png,groundtruth,1_9.txt,val
Trends in Cancer,10_8,Which of the following options best describe the cover story?,"Ferroptotic therapy represents a promising approach in cancer treatment
by exploiting nonapoptotic cell death, characterized by iron accumulation and
uncontrolled lipid peroxidation, to target cancer cells. However, its use has potential
adverse effects as well as context-dependent effects on anticancer immunity that
require consideration for successful implementation. In this issue, Catanzaro et al.
propose that immunogenicity of ferroptosis is context-dependent. In another review,
Liu et al. discuss the adverse events related to targeted ferroptosis-based therapy. The
cover depicts a golfer using his nine-iron to hit the ball (inducing ferroptosis).
Depending
on the conditions (TME, immune cells, etc.), the ball can go into the hole (on target
effect, killing cancer cell) or land outside the fairway (off-target effect, adverse
events or
immunogenicity). Cover image from gettyimages/chuwy.",D,MAC_Bench/Cell/Cover/Trends in Cancer/3_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_6.png,clip,3_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/4_5.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_5.png,ave_1,4_5.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,vitg,10_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_8.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_8.png,groundtruth,10_8.txt,train
Nature Chemistry,16_5,Which of the following options best describe the cover story?,"Shaping a supramolecular synthetic cytoskeleton
Cells are able to modify their shape and adapt to the environment because their cytoskeleton, which is composed of proteins, forms a dynamic framework. Ronit Freeman and co-workers have now used programmable peptide–DNA technology to build a synthetic cytoskeleton in artificial cells that can change shape, enabling the cells to react to their surroundings. The cover shows an artistic rendition of cytoskeletal-reinforced synthetic cells.
See Freeman et al.
Image: Justin Hill and Ronit Freeman, UNC-Chapel Hill. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Chemistry/12_8.png,MAC_Bench/Nature/Cover/Nature Chemistry/12_8.png,ave_2,12_8.txt,MAC_Bench/Nature/Cover/Nature Chemistry/15_11.png,MAC_Bench/Nature/Cover/Nature Chemistry/15_11.png,vith,15_11.txt,MAC_Bench/Nature/Cover/Nature Chemistry/8_2.png,MAC_Bench/Nature/Cover/Nature Chemistry/8_2.png,clip,8_2.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_5.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_5.png,groundtruth,16_5.txt,train
Journal of the American Chemical Society,2024_11,Which of the following options best describe the cover story?,"A ligand-receptor-anchored nanopore is designed that mimics natural structural adaptability and favorable orientation of the ligand. It facilitates real-time mapping of multivalent binding pathways and kinetics in native states at the single monomeric subunit level, providing a new tool for high-throughput screening of antibodies or drugs.",D,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_42.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_42.png,vith,2011_42.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_15.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_15.png,clip,2009_15.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_45.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_45.png,vitg,2023_45.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_11.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_11.png,groundtruth,2024_11.txt,val
Nature Machine Intelligence,6_9,Which of the following options best describe the cover story?,"Generating turbulence trajectories with diffusion models
Diffusion models can be used to generate intricate and detailed particle paths in turbulent flows, reflecting the complex nature of fluid motion. By means of statistical analysis, Li et al. show that diffusion models can capture the full complexity of turbulent dynamics and generalize to extreme events.
See Li et al.
Image: Michele Buzzicotti, University of Rome Tor Vergata. Cover design: Amie Fernandez",A,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_9.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_9.png,groundtruth,6_9.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_1.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_1.png,vith,4_1.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_6.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_6.png,ave_3,3_6.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_2.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_2.png,clip,6_2.txt,val
Nature Cancer,5_2,Which of the following options best describe the cover story?,"Charting tumor evolution with the Human Tumor Atlas Network
The Human Tumor Atlas Network explores tumor evolution in time and space by compiling integrative atlases of cellular, molecular and histological tumor features.
See Iglesia et al. , Zhu et al. and Esplin et al.
Image: Lilawa.com / Alamy Stock Photo. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Cancer/5_2.png,MAC_Bench/Nature/Cover/Nature Cancer/5_2.png,groundtruth,5_2.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_11.png,MAC_Bench/Nature/Cover/Nature Cancer/5_11.png,vitg,5_11.txt,MAC_Bench/Nature/Cover/Nature Cancer/1_10.png,MAC_Bench/Nature/Cover/Nature Cancer/1_10.png,vith,1_10.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_7.png,MAC_Bench/Nature/Cover/Nature Cancer/4_7.png,clip,4_7.txt,val
BDJ,237_12,Which of the following options best describe the cover story?,"In this issue
This issue features articles on dental anxiety, cardiothoracic surgery, and the very first of our new “Review” article type!

Cover image: From 2005. A dentist painting her view from the practice ‘window on the world’, inspired by the selected cover image as an artwork hanging on the surgery wall (original cover by Irfan Ahmad, taken from Vol 199 Issue 4, 27 August 2005). See ‘Behind the new cover series’ written by Stephen in the News and Views section for further explanation.
©Tim Marrs, incorporating original cover art by Irfan Ahmad",D,MAC_Bench/Nature/Cover/BDJ/237_5.png,MAC_Bench/Nature/Cover/BDJ/237_5.png,vith,237_5.txt,MAC_Bench/Nature/Cover/BDJ/229_3.png,MAC_Bench/Nature/Cover/BDJ/229_3.png,clip,229_3.txt,MAC_Bench/Nature/Cover/BDJ/235_1.png,MAC_Bench/Nature/Cover/BDJ/235_1.png,vitg,235_1.txt,MAC_Bench/Nature/Cover/BDJ/237_12.png,MAC_Bench/Nature/Cover/BDJ/237_12.png,groundtruth,237_12.txt,train
Science Signaling,2007_385,Which of the following options best describe the cover story?,"COVER This week features a  Perspective on kinase chaperones in yeast. The image shows Cdc37 and Hsp90 chaperoning a yeast kinase. [Image: Christopher Bickel, AAAS]",B,MAC_Bench/Science/Cover/Science Signaling/3_137.png,MAC_Bench/Science/Cover/Science Signaling/3_137.png,vith,3_137.txt,MAC_Bench/Science/Cover/Science Signaling/2007_385.png,MAC_Bench/Science/Cover/Science Signaling/2007_385.png,groundtruth,2007_385.txt,MAC_Bench/Science/Cover/Science Signaling/12_609.png,MAC_Bench/Science/Cover/Science Signaling/12_609.png,clip,12_609.txt,MAC_Bench/Science/Cover/Science Signaling/7_342.png,MAC_Bench/Science/Cover/Science Signaling/7_342.png,vitg,7_342.txt,train
ACS ES&T Air,2025_2,Which of the following options best describe the cover story?,Computational models of atmospheric composition do not always make scientifically trustworthy predictions. This is especially true for machine learning and AI tools that learn patterns from data without knowing the physical laws governing those patterns. We introduce a corrective approach that minimally adjusts the predicted concentrations of chemical species to guarantee conservation of mass.,C,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,ave_3,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,ave_2,2024_3.txt,train
ACS Applied Polymer Materials,2024_9,Which of the following options best describe the cover story?,"Chitosan-grafted pomegranate extract hydrogel, as a cost-effective and bio-based approach, effectively absorbs moisture and provides antibacterial and antioxidant properties, demonstrating a promising alternative as a food packaging material.",B,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,ave_2,2025_2.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_13.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_13.png,ave_3,2024_13.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_7.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_7.png,clip,2022_7.txt,train
Nature Structural & Molecular Biology,31_12,Which of the following options best describe the cover story?,"NSMB’s 30th anniversary
To celebrate Nature Structural & Molecular Biology’s 30th anniversary, our cover features original artwork that was submitted by our reader Pedro Rebelo-Guiomar for our cover competition.
See Rebelo-Guiomar and Editorial
IMAGE CREDIT: Pedro Rebelo-Guiomar, University of Cambridge. COVER DESIGN: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_9.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_9.png,vith,26_9.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,clip,28_8.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_12.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_12.png,groundtruth,31_12.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/24_7.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/24_7.png,ave_2,24_7.txt,val
Current Biology,35_2,Which of the following options best describe the cover story?,"On the cover: The microscopic fossil ostracod crustacean shown is used as a time machine
to reconstruct past deep-sea ecosystem changes. In this issue, Moriaki Yasuhara, Huai-Hsuan May Huang, Raine Wing Ki Chong, and their colleagues revealed the 500,000-year history of the Southern Ocean deep-sea ecosystem. The researchers
found that the present-day Southern Ocean deep-sea ecosystem was established at a
major climatic transition ∼430,000 years ago. After that, both deep-water temperature
and food supply (via surface plankton production related to iron fertilization that
eventually sinks to the deep-sea floor) substantially affected their deep-sea ecosystem
in different ways. The team highlights the importance of the Southern Ocean deep-sea
ecosystem as a “canary in the coal mine” for future anthropogenic climatic changes
on our planet, and especially highlights the need to carefully think about how we
proceed with ocean-based climate interventions as they mitigate temperature rise but
also affect surface production. Cover image: Jingwen Zhang, Raine Wing Ki Chong, Huai-Hsuan
May Huang, and Moriaki Yasuhara.",A,MAC_Bench/Cell/Cover/Current Biology/35_2.png,MAC_Bench/Cell/Cover/Current Biology/35_2.png,groundtruth,35_2.txt,MAC_Bench/Cell/Cover/Current Biology/22_1.png,MAC_Bench/Cell/Cover/Current Biology/22_1.png,clip,22_1.txt,MAC_Bench/Cell/Cover/Current Biology/31_16.png,MAC_Bench/Cell/Cover/Current Biology/31_16.png,ave_1,31_16.txt,MAC_Bench/Cell/Cover/Current Biology/21_3.png,MAC_Bench/Cell/Cover/Current Biology/21_3.png,vith,21_3.txt,train
Nature Food,5_1,Which of the following options best describe the cover story?,"Africa’s pastoral–agropastoral transition zones
Africa’s most extensive transition zones between the arid–semi-arid agropastoral system and the livestock-only pastoral system occur in the Sahelian and Sudanian belt. Livestock-based pastoral and agropastoral production systems predominate in the arid–semi-arid zones of Africa. Livestock have considerable socio-cultural and economic importance in these regions, supporting millions of livelihoods. Transition zones are expected to suffer with the aggravation of climate change, particularly through the impact of heat stress on agricultural production. Although adaptation strategies offer some relief, the future of these systems requires a long-term vision.
See Thornton et al.
Image: David Fettes/ Connect Images/Getty. Cover design: Tulsi Voralia",C,MAC_Bench/Nature/Cover/Nature Food/2_11.png,MAC_Bench/Nature/Cover/Nature Food/2_11.png,ave_2,2_11.txt,MAC_Bench/Nature/Cover/Nature Food/4_12.png,MAC_Bench/Nature/Cover/Nature Food/4_12.png,ave_3,4_12.txt,MAC_Bench/Nature/Cover/Nature Food/5_1.png,MAC_Bench/Nature/Cover/Nature Food/5_1.png,groundtruth,5_1.txt,MAC_Bench/Nature/Cover/Nature Food/1_6.png,MAC_Bench/Nature/Cover/Nature Food/1_6.png,clip,1_6.txt,val
Cell Reports Methods,4_4,Which of the following options best describe the cover story?,"On the cover: In this issue, Hall et al. introduce the MAP (migration analysis of peripheral immune cells) chip, a microfluidic
platform for live, single-cell profiling of immune cell migration in response to a
variety of stimuli. The cover image depicts tracking of human monocytes (multicolored)
navigating through the chemotactic maze microchannels in the MAP chip and is courtesy
of Alice Tsai and Mehdi Jorfi.",A,MAC_Bench/Cell/Cover/Cell Reports Methods/4_4.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_4.png,groundtruth,4_4.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/5_1.png,MAC_Bench/Cell/Cover/Cell Reports Methods/5_1.png,ave_2,5_1.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,clip,2_11.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_2.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_2.png,vitg,2_2.txt,train
Journal of the American Chemical Society,2024_3,Which of the following options best describe the cover story?,"Hierarchically aligned zeolite crystals with tunable a-axis substructures were synthesized by using the dual structure-directing agents, tetrapropylammonium hydroxide and tetraethylammonium hydroxide. The ordered hierarchical structures enable directional mass transport, resulting in enhanced diffusion, catalytic activity, and stability.",C,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_47.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_47.png,vitg,2016_47.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_22.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_22.png,vith,2019_22.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_3.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2012_33.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2012_33.png,clip,2012_33.txt,train
Nature Structural & Molecular Biology,31_8,Which of the following options best describe the cover story?,"Mechanisms of RNA processing and splicing
In this issue, we feature studies investigating RNA processing, including mechanisms of mRNA splicing, biogenesis of the splicing machinery, decoding of mRNA by the ribosome, and deadenylation of mRNA for degradation.
See Editorial
IMAGE CREDIT: Fabio Pagani / Alamy Stock Photo. COVER DESIGN: Allen Beattie",D,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_2.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_2.png,ave_2,26_2.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_10.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_10.png,clip,25_10.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,ave_1,28_8.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_8.png,groundtruth,31_8.txt,train
Nature Reviews Cardiology,21_5,Which of the following options best describe the cover story?,"Protein glycosylation, inspired by the Review on p525.
Cover design: S. Whitham",A,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_5.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_5.png,groundtruth,21_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/22_1.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/22_1.png,ave_3,22_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,vitg,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_11.png,clip,20_11.txt,train
Nature Human Behaviour,8_5,Which of the following options best describe the cover story?,"BOLD troubles
Functional magnetic resonance imaging (fMRI) is a key tool for understanding brain function. Korponay et al. show that the blood oxygenation level-dependent (BOLD) signal — which fMRI uses to measure brain activity — is susceptible to artefacts from low-frequency blood flow signals (sLFOs), which can produce false positives in functional connectivity. These artefacts, linked to changes in respiration and heart rate during scanning, distort connectivity measures. The authors develop a specialized sLFO denoising method, which improves the accuracy and reliability of functional connectivity findings.
See Korponay et al.
Image: Marc Raley. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_9.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_9.png,vitg,5_9.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/3_12.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/3_12.png,clip,3_12.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_5.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_5.png,groundtruth,8_5.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,vith,8_2.txt,train
Cell Systems,15_3,Which of the following options best describe the cover story?,"On the cover: Clustering and cell type annotation results of Stereo-seq soybean root
data using raw data with added noise and data denoised using SpotGF. In this issue
of Cell Systems, Du et al. introduce SpotGF, a method for denoising spatially resolved transcriptomics data
via an optimal transport-based gene filtering algorithm. Image credit: the authors.",C,MAC_Bench/Cell/Cover/Cell Systems/12_8.png,MAC_Bench/Cell/Cover/Cell Systems/12_8.png,vith,12_8.txt,MAC_Bench/Cell/Cover/Cell Systems/14_8.png,MAC_Bench/Cell/Cover/Cell Systems/14_8.png,vitg,14_8.txt,MAC_Bench/Cell/Cover/Cell Systems/15_3.png,MAC_Bench/Cell/Cover/Cell Systems/15_3.png,groundtruth,15_3.txt,MAC_Bench/Cell/Cover/Cell Systems/8_4.png,MAC_Bench/Cell/Cover/Cell Systems/8_4.png,clip,8_4.txt,train
iScience,27_7,Which of the following options best describe the cover story?,"On the cover: Music and social interactions are fundamental sources of pleasure in
our lives. But does sharing music enhance this pleasure? In three online experiments,
Curzel et al. simulated shared music experiences: individuals on an online platform believed they
were listening to music alone or with others, visually represented as pins on a map.
Consistently, the authors found that the social context significantly increased participants’
enjoyment of music, with greater pleasure reported as social sharing increased. Moreover,
this heightened pleasure fostered prosocial behavior and improved memory of the music
itself. Hence, the cover is a graphical illustration representing the heightened pleasure
experienced when listening to music with others connected worldwide simultaneously.
Image credit: Grazia Fino.",A,MAC_Bench/Cell/Cover/iScience/27_7.png,MAC_Bench/Cell/Cover/iScience/27_7.png,groundtruth,27_7.txt,MAC_Bench/Cell/Cover/iScience/26_1.png,MAC_Bench/Cell/Cover/iScience/26_1.png,ave_2,26_1.txt,MAC_Bench/Cell/Cover/iScience/23_9.png,MAC_Bench/Cell/Cover/iScience/23_9.png,clip,23_9.txt,MAC_Bench/Cell/Cover/iScience/26_3.png,MAC_Bench/Cell/Cover/iScience/26_3.png,vitg,26_3.txt,val
Journal of Chemical Theory and Computation,2025_2,Which of the following options best describe the cover story?,s-molecular dynamics simulations and umbrella sampling simulations allow the rationalization of New Delhi metallo-β-lactamase 1 enzyme inhibition by ebselen and ebsulfur to contrast antibiotic resistance. The role of chalcogen,C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,vith,2021_12.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2018_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2018_12.png,vitg,2018_12.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2025_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_21.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_21.png,clip,2024_21.txt,train
Nature Reviews Psychology,3_11,Which of the following options best describe the cover story?,"In this Review, Ayzenberg and Behrmann examine the maturation of object recognition from infancy through childhood.
Cover design: David Johnston",B,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_11.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_11.png,groundtruth,3_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_5.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_4.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_4.png,ave_1,1_4.txt,test
Trends in Ecology & Evolution,39_5,Which of the following options best describe the cover story?,"Agriculture is a primary cause of the biodiversity crisis. On pages 726–733,
Teja Tscharntke and colleagues argue that a mix of on- and off-field measures is needed
to conserve biodiversity, overcoming the false dichotomy of the land sharing-sparing
debate. The cover image shows wheat—oilseed rape intercropping (near Göttingen,
Germany) to reduce field sizes, increase landscape heterogeneity, and to enhance
biodiversity and ecosystem services such as biological control. Photo credit: Uwe
Holst.",B,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_3.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_3.png,clip,34_3.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_5.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_5.png,groundtruth,39_5.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_1.png,vith,29_1.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_9.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_9.png,vitg,29_9.txt,train
Cell Chemical Biology,31_1,Which of the following options best describe the cover story?,"On the cover: Kotagiri et al. identified a potent and highly selective PROTAC (proteolysis targeting chimera),
YD23, that degrades SMARCA2 (dark green) in the SWI/SNF complex through proteosomes.
SMARCA2 degradation inactivates the SWI/SNF complex in the nucleus leading to reduced
chromatin accessibility at enhancers of genes involved in cell-cycle progression and
inhibits the growth of SMARCA4-mutant cancer cells. Image credit: Sasi Kotagiri, Nicholas
Blazanin, and Yonathan Lissanu.",D,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_9.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_9.png,vith,18_9.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/22_10.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/22_10.png,vitg,22_10.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/27_12.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/27_12.png,clip,27_12.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_1.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_1.png,groundtruth,31_1.txt,train
Trends in Cancer,11_1,Which of the following options best describe the cover story?,"In this issue, Kadali and Shoshani discuss the relationship between
abnormal nuclear structures and the formation of gene amplifications in cancer,
emphasizing their role in tumor heterogeneity and therapy resistance. The cover image
depicts cancer cells breaking chromosome bridges with amplified DNA, generating
ecDNA enclosed within micronuclei. These ecDNA-rich micronuclei, portrayed as
mobile carriers, travel along a winding road symbolizing the dynamic ""route to tumor
evolution."" Along this path, cancer cells act as builders or laborers, depositing
the
ecDNA-rich micronuclei into the tumor mass, highlighting their contribution to tumor
heterogeneity. Cover image design and illustration by Shilpa Madhavan.",C,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,vitg,10_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,vith,3_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/11_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/11_1.png,groundtruth,11_1.txt,MAC_Bench/Cell/Cover/Trends in Cancer/6_5.png,MAC_Bench/Cell/Cover/Trends in Cancer/6_5.png,clip,6_5.txt,train
Lab Animal,53_9,Which of the following options best describe the cover story?,"In vivo modeling of postpartum hemorrhage
Severe bleeding after childbirth – postpartum haemorrhage (PPH) – is a leading cause of maternal mortality worldwide. Several animal models have been developed for testing novel therapeutic materials; however, these animals differ considerably from the anatomy and physiology of a postpartum woman. In a new Review, Hargett, Leslie et al. critically evaluate available animal models of PPH and propose additional methods for modeling PPH in vivo.
See Gaharwar et al.
Cover image: Debbie Maizels. Cover design: Debbie Maizels.",C,MAC_Bench/Nature/Cover/Lab Animal/50_10.png,MAC_Bench/Nature/Cover/Lab Animal/50_10.png,vitg,50_10.txt,MAC_Bench/Nature/Cover/Lab Animal/50_4.png,MAC_Bench/Nature/Cover/Lab Animal/50_4.png,clip,50_4.txt,MAC_Bench/Nature/Cover/Lab Animal/53_9.png,MAC_Bench/Nature/Cover/Lab Animal/53_9.png,groundtruth,53_9.txt,MAC_Bench/Nature/Cover/Lab Animal/48_10.png,MAC_Bench/Nature/Cover/Lab Animal/48_10.png,ave_0,48_10.txt,test
Nature Climate Change,14_5,Which of the following options best describe the cover story?,"Debating coral futures
Coral reef bleaching is a common image of climate change impacts on marine ecosystems. In this month’s issue, we feature three opinion pieces discussing the future of coral reefs, including the need to move beyond narratives of global loss and considerations over the costs and benefits of choosing active intervention pathways.
See Streit et al., Webster et al. and McClanahan
Image: Marianne Purdie/Moment/Getty Images. Cover design: Debbie Maizels",A,MAC_Bench/Nature/Cover/Nature Climate Change/14_5.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_5.png,groundtruth,14_5.txt,MAC_Bench/Nature/Cover/Nature Climate Change/7_4.png,MAC_Bench/Nature/Cover/Nature Climate Change/7_4.png,clip,7_4.txt,MAC_Bench/Nature/Cover/Nature Climate Change/10_7.png,MAC_Bench/Nature/Cover/Nature Climate Change/10_7.png,vitg,10_7.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_6.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_6.png,ave_3,14_6.txt,train
ACS Central Science,2024_10,Which of the following options best describe the cover story?,A metal-free layered organic cathode material for lithium-ion batteries intercalates Li+ and stores more energy in a shorter charging time than inorganic incumbents.,B,MAC_Bench/ACS/Cover/ACS Central Science/2024_7.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_7.png,clip,2024_7.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_10.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_4.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_4.png,vith,2024_4.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_12.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_12.png,ave_3,2023_12.txt,train
ACS Sustainable Resource Management,2025_1,Which of the following options best describe the cover story?,Thermoprocessing glycerol/water-plasticized biopolymers with bio-waste using industrial methods to replace industrial processing of plastics with renewable materials.,B,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_1.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,ave_3,2024_10.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,ave_2,2024_9.txt,test
Crystal Growth & Design,2024_16,Which of the following options best describe the cover story?,"The new 3D coordination polymer, as a result of the connection between the 2D extension of hexanuclear iron(II) motifs, which gives rise to a metamagnetic behavior, and the hysteresis loop with a high coercive field.",B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_1.png,vitg,2016_1.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_16.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_16.png,groundtruth,2024_16.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2010_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2010_8.png,clip,2010_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,vith,2018_1.txt,train
Nature Reviews Clinical Oncology,21_8,Which of the following options best describe the cover story?,"The two faces of copper metabolism in cancer, inspired by the Review on p370.
Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_8.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_8.png,groundtruth,21_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_11.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_11.png,clip,18_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_12.png,vitg,20_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,vith,19_10.txt,train
Nature Chemistry,17_2,Which of the following options best describe the cover story?,"Four-electron reduction of benzene
The reduction of benzene by molecular complexes remains a significant synthetic challenge, and it typically requires harsh reaction conditions involving group 1 metals. Now, a team led by Mathew Anker and Laurent Maron has shown that a highly polar organometallic samarium alkyl complex enables the four-electron reduction of benzene without the need for a group 1 metal. An artistic rendering of this reaction is pictured on the cover.
See Anker, Maron et al.
Image: Matthew Evans, Monash University. Cover design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/Nature Chemistry/17_2.png,MAC_Bench/Nature/Cover/Nature Chemistry/17_2.png,groundtruth,17_2.txt,MAC_Bench/Nature/Cover/Nature Chemistry/7_10.png,MAC_Bench/Nature/Cover/Nature Chemistry/7_10.png,vitg,7_10.txt,MAC_Bench/Nature/Cover/Nature Chemistry/13_4.png,MAC_Bench/Nature/Cover/Nature Chemistry/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/Nature Chemistry/15_7.png,MAC_Bench/Nature/Cover/Nature Chemistry/15_7.png,ave_1,15_7.txt,train
Journal of the American Chemical Society,2024_31,Which of the following options best describe the cover story?,"The strikingly different photosensitization mechanisms of two nanohybrids based on CsPbBr3 nanocrystals functionalized with two BODIPY dyes have been thoroughly investigated by using a battery of spectroscopic techniques combined with theoretical calculations, which together provide a whole vision of the nanohybrid to be used in light-driven applications.",A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_31.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_31.png,groundtruth,2024_31.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2021_24.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2021_24.png,vith,2021_24.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,vitg,2010_30.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_51.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_51.png,clip,2018_51.txt,val
Science Advances,11_3,Which of the following options best describe the cover story?,"ONLINE COVER Two researchers exploring Herbstlabyrinth Cave, Germany. Located 70 km from the Laacher See volcano, Herbstlabyrinth Cave sits within the main fallout area of the Laacher See Eruption (LSE) event that occurred around 13,000 years ago. Using mineral deposits from the cave, Warken et al. developed a precise chronology of volcanic sulfur spikes and were able to link the LSE to a previously unidentified sulphate spike in the Greenland ice core record. This synchronized calendar shows the LSE was not a cause of the Younger Dryas (YD) climate cooling event that occurred 150 years later. Credit: Georg Taffet and SAH (Speläologische Arbeitsgemeinschaft Hessen e.V.)",C,MAC_Bench/Science/Cover/Science Advances/9_42.png,MAC_Bench/Science/Cover/Science Advances/9_42.png,ave_2,9_42.txt,MAC_Bench/Science/Cover/Science Advances/9_5.png,MAC_Bench/Science/Cover/Science Advances/9_5.png,ave_3,9_5.txt,MAC_Bench/Science/Cover/Science Advances/11_3.png,MAC_Bench/Science/Cover/Science Advances/11_3.png,groundtruth,11_3.txt,MAC_Bench/Science/Cover/Science Advances/10_35.png,MAC_Bench/Science/Cover/Science Advances/10_35.png,clip,10_35.txt,val
Science Signaling,2007_406,Which of the following options best describe the cover story?,COVER This week features a  Perspective on how day length modulates the behavioral effects of estrogens. [Image: J. Foxx/Getty Images],C,MAC_Bench/Science/Cover/Science Signaling/2_70.png,MAC_Bench/Science/Cover/Science Signaling/2_70.png,clip,2_70.txt,MAC_Bench/Science/Cover/Science Signaling/12_583.png,MAC_Bench/Science/Cover/Science Signaling/12_583.png,vitg,12_583.txt,MAC_Bench/Science/Cover/Science Signaling/2007_406.png,MAC_Bench/Science/Cover/Science Signaling/2007_406.png,groundtruth,2007_406.txt,MAC_Bench/Science/Cover/Science Signaling/9_429.png,MAC_Bench/Science/Cover/Science Signaling/9_429.png,vith,9_429.txt,train
iScience,28_2,Which of the following options best describe the cover story?,"On the cover: The illustration represents the core concept of collaborative trajectory
following in a connected and automated airspace environment driven by 5G technology.
Leveraging the low-latency global 5G network, aircraft acquire the capability for
high-speed information exchange and real-time interaction necessary for global connectivity.
By integrating intelligent aircraft following and interactions within autonomous connected
airspace, the system achieves a dynamic and orderly stability in trajectory following,
demonstrating adaptive resilience to environmental disturbances. This highlights the
creation of a highly connected, collaborated, and stable future air traffic operation
system. This vision aligns with the framework proposed by Huang et al., offering an intelligent connected aircraft-following model. Image source: Xiao Huang.",B,MAC_Bench/Cell/Cover/iScience/25_5.png,MAC_Bench/Cell/Cover/iScience/25_5.png,ave_2,25_5.txt,MAC_Bench/Cell/Cover/iScience/28_2.png,MAC_Bench/Cell/Cover/iScience/28_2.png,groundtruth,28_2.txt,MAC_Bench/Cell/Cover/iScience/28_3.png,MAC_Bench/Cell/Cover/iScience/28_3.png,clip,28_3.txt,MAC_Bench/Cell/Cover/iScience/18_1.png,MAC_Bench/Cell/Cover/iScience/18_1.png,ave_3,18_1.txt,val
Matter,8_1,Which of the following options best describe the cover story?,"On the cover: This cover features conductive thin films designed to protect drones
in extreme weather conditions. In this issue, Wu and colleagues explore material engineering through the integration of experiments and theories.
By combining layer-by-layer assembly and graph theory, electrical properties are modeled
based on the complex structures of the nanoscale networks. Image courtesy of the authors.",A,MAC_Bench/Cell/Cover/Matter/8_1.png,MAC_Bench/Cell/Cover/Matter/8_1.png,groundtruth,8_1.txt,MAC_Bench/Cell/Cover/Matter/8_2.png,MAC_Bench/Cell/Cover/Matter/8_2.png,clip,8_2.txt,MAC_Bench/Cell/Cover/Matter/2_6.png,MAC_Bench/Cell/Cover/Matter/2_6.png,ave_1,2_6.txt,MAC_Bench/Cell/Cover/Matter/2_1.png,MAC_Bench/Cell/Cover/Matter/2_1.png,vitg,2_1.txt,train
ACS Applied Optical Materials,2024_1,Which of the following options best describe the cover story?,"The ACS AMI Family “2024 Early Career Forum” highlights groundbreaking research and innovative ideas from the emerging authors in the scientific community on a broad range of topics. This edition of the Forum showcases 135 exceptional contributions from early-career scientists worldwide, published across ACS Applied Materials & Interfaces, ACS Applied Bio Materials, ACS Applied Electronic Materials, ACS Applied Engineering Materials, ACS Applied Energy Materials, ACS Applied Nano Materials, ACS Applied Optical Materials, and ACS Applied Polymer Materials.",C,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2025_1.png,vitg,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_4.png,clip,2023_4.txt,train
Science Immunology,10_104,Which of the following options best describe the cover story?,"ONLINE COVER Immune Hotspots in Multiple Myeloma. Multiple myeloma (MM) is a plasma cell malignancy that develops in the bone marrow but can expand as breakout lesions into neighboring soft tissues as the disease progresses. Using single-cell and spatial multiomics, Lutz et al. compared the cellular composition of bone marrow–confined MM and breakout lesions in patients with newly diagnosed MM. Within breakout lesions, “immune islands” containing focal accumulation of immune cells served as sites for T cell clonal expansion and tumor genomic diversification. This month’s cover image, obtained using multiplexed imaging, shows an immune island within a breakout lesion from a patient with MM. Myeloid cells (yellow), NK cells (orange), and T cells (pink) surround vascular cells (green) and diffusely infiltrate areas dominated by plasma cells (blue). Credit: Johanna Wagner/German Cancer Research Center and National Center for Tumor Diseases Heidelberg and Niels Weinhold/Heidelberg University Hospital and German Cancer Research Center",A,MAC_Bench/Science/Cover/Science Immunology/10_104.png,MAC_Bench/Science/Cover/Science Immunology/10_104.png,groundtruth,10_104.txt,MAC_Bench/Science/Cover/Science Immunology/6_56.png,MAC_Bench/Science/Cover/Science Immunology/6_56.png,vith,6_56.txt,MAC_Bench/Science/Cover/Science Immunology/8_90.png,MAC_Bench/Science/Cover/Science Immunology/8_90.png,clip,8_90.txt,MAC_Bench/Science/Cover/Science Immunology/3_27.png,MAC_Bench/Science/Cover/Science Immunology/3_27.png,vitg,3_27.txt,train
Nature Cities,1_12,Which of the following options best describe the cover story?,"Addressing heat exposure
Heat waves are becoming increasingly common in cities worldwide. Geogescu et al. estimate the potential to reduce the exposure of US city populations to extreme heat by comparing two methods: adapting in-place and mitigating local climate-warming activities.
See Georgescu et al.
Image: Sean Pavone/Alamy Stock Photo. Cover Design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Cities/1_12.png,MAC_Bench/Nature/Cover/Nature Cities/1_12.png,groundtruth,1_12.txt,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,ave_1,1_7.txt,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,ave_2,1_3.txt,train
Organic Letters,2025_2,Which of the following options best describe the cover story?,"As the Lunar New Year in the Year of the Snake approached, we developed a method for the addition of Grignard reagents to pillar[4]arene[1]benzoquinone monoxime, enabling the functionalization of pillar[4]arene derivatives. This evoked imagery of the snake, sleek, slithering, and symbolic of intuition, transformation, and growth in Chinese culture, bringing good fortune to the chemists who orchestrated this magical transformation from substrate to diverse products.",A,MAC_Bench/ACS/Cover/Organic Letters/2025_2.png,MAC_Bench/ACS/Cover/Organic Letters/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Organic Letters/2024_42.png,MAC_Bench/ACS/Cover/Organic Letters/2024_42.png,vitg,2024_42.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_5.png,MAC_Bench/ACS/Cover/Organic Letters/2025_5.png,vith,2025_5.txt,MAC_Bench/ACS/Cover/Organic Letters/2022_43.png,MAC_Bench/ACS/Cover/Organic Letters/2022_43.png,clip,2022_43.txt,train
One Earth,7_9,Which of the following options best describe the cover story?,"On the cover: Climate change is reshaping insect abundances and ecosystems, sometimes
with severe consequences for humanity, but it remains difficult to predict how and
why insects move. In this month's thematic issue on insect movement, a new review
by Terblanche and colleagues identifies key traits that facilitate insect movement in response to warming climate.
Here, a cloud of locusts, a species possessing all the traits, is spread across a
once verdant field, a gloomy prediction for the future. The cover image was designed
by Casey Williams (https://caseylynnwilliams.com/).",C,MAC_Bench/Cell/Cover/One Earth/5_4.png,MAC_Bench/Cell/Cover/One Earth/5_4.png,ave_3,5_4.txt,MAC_Bench/Cell/Cover/One Earth/6_1.png,MAC_Bench/Cell/Cover/One Earth/6_1.png,ave_2,6_1.txt,MAC_Bench/Cell/Cover/One Earth/7_9.png,MAC_Bench/Cell/Cover/One Earth/7_9.png,groundtruth,7_9.txt,MAC_Bench/Cell/Cover/One Earth/5_9.png,MAC_Bench/Cell/Cover/One Earth/5_9.png,clip,5_9.txt,train
Nature Reviews Physics,6_10,Which of the following options best describe the cover story?,"The cover of this issue illustrates the measurement of the W boson mass. See Kotwal
Cover design: Susanne Harris.",A,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_10.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_10.png,groundtruth,6_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_4.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_4.png,clip,3_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_12.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_12.png,vith,3_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_8.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_8.png,vitg,5_8.txt,train
Nature Chemical Biology,20_3,Which of the following options best describe the cover story?,"Respiration guides living materials
Graham et al. developed engineered living materials with controllable mechanic properties in response to environmental stimuli. This was achieved by programming bacteria (orange) embedded in the hydrogel matrix with genetic logic circuits to control the expression of MtrC (foreground), a membrane-associated protein that regulates the microbial respiration process.
See Graham et al. and Atkinson
Image: Ismar Miniel Mahfoud, The University of Texas at Austin; protein structure from PDB; PDB ID: 4LM8. Cover design: Alex Wing",B,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,ave_1,17_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_3.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_3.png,groundtruth,20_3.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_4.png,vitg,18_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_3.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_3.png,clip,17_3.txt,train
Nature Human Behaviour,8_10,Which of the following options best describe the cover story?,"Individual sleep needs
How much sleep is necessary for optimal cognitive function and brain health? Human sleep deprivation experiments in the laboratory, observational studies and the behavioural ecology and evolution literature provide different answers to this question. Fjell and Walhovd adopt a transdisciplinary view of the evidence and argue that individual sleep need is highly flexible and affected by environmental factors, individual needs and motivation. This flexibility and broader context are frequently overlooked in laboratory-based sleep restriction studies and in sleep recommendations, but are important to take into account for a more ecologically valid view of human sleep needs.
See Fjell and Walhovd
Cover image: Viktoriia Patapova/iStock/Getty Images Plus. Cover design: Bethany Vukomanovic.",C,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,ave_3,8_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_12.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_12.png,vitg,5_12.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_10.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_10.png,groundtruth,8_10.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_8.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_8.png,clip,6_8.txt,train
ACS Synthetic Biology,2024_10,Which of the following options best describe the cover story?,"Cell-free protein synthesis (CFPS) can deliver medicines and biosensors on-demand, even in low-resource settings. Kocalar et al. prove that CFPS works in the microgravity environment of the International Space Station, paving the way for portable health tools and environmental monitors for space travelers.",D,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2014_7.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2014_7.png,vith,2014_7.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_2.png,vitg,2024_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_9.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_9.png,clip,2023_9.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_10.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_10.png,groundtruth,2024_10.txt,test
Lab Animal,53_5,Which of the following options best describe the cover story?,"New tool for monitoring mouse subretinal fibrosis
Efficient tools for monitoring fibrosis-related changes in neovascular age-related macular degeneration are lacking. Linder et al. describe the first use of fluorescently labeled collagen hybridizing peptides to directly image collagen remodeling and monitor fibrosis in two mouse models of ocular neovascularization.
See Linder
Cover image: Zentangle / iStock / Getty Images Plus and Marina Spence. Cover design: Marina Spence.",A,MAC_Bench/Nature/Cover/Lab Animal/53_5.png,MAC_Bench/Nature/Cover/Lab Animal/53_5.png,groundtruth,53_5.txt,MAC_Bench/Nature/Cover/Lab Animal/49_7.png,MAC_Bench/Nature/Cover/Lab Animal/49_7.png,ave_2,49_7.txt,MAC_Bench/Nature/Cover/Lab Animal/49_9.png,MAC_Bench/Nature/Cover/Lab Animal/49_9.png,ave_1,49_9.txt,MAC_Bench/Nature/Cover/Lab Animal/47_9.png,MAC_Bench/Nature/Cover/Lab Animal/47_9.png,clip,47_9.txt,train
Cell Host&Microbe,32_12,Which of the following options best describe the cover story?,"On the cover: In this Cell Host & Microbe issue, Yu et al. report that oral administration of Bifidobacterium longum during the perioperative phase of hepatocellular carcinoma treatment significantly
enhances postoperative liver function, extends survival, and reduces hospitalization.
This effect is mediated by the modulation of gut microbiota and metabolites, including
5-hydroxytryptamine, secondary bile acids, and short-chain fatty acids. These factors
collectively promote hepatocyte growth while inhibiting liver fibrosis and inflammation.
Also in this issue Lehmann and colleagues demonstrate that fecal metabolite profiling
can identify liver transplant patients with heightened risk for post-operative infections.
These studies collectively illustrate how the gut-liver axis can impact disease/treatment
outcome. The cover image illustrates this therapeutic intervention's impact on the
liver's healing process, with Bifidobacterium longum playing a central role.",A,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_12.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_12.png,groundtruth,32_12.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,clip,27_5.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/22_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/22_4.png,vith,22_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,vitg,30_3.txt,train
ACS Catalysis,2024_6,Which of the following options best describe the cover story?,"Theory and experiment revealed important geometric and electronic effects of C60 in promoting the catalytic reactions by reversibly accepting and donating electrons to the adsorbed copper, resulting in the alternating formation of",B,MAC_Bench/ACS/Cover/ACS Catalysis/2022_21.png,MAC_Bench/ACS/Cover/ACS Catalysis/2022_21.png,vith,2022_21.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_6.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2022_13.png,MAC_Bench/ACS/Cover/ACS Catalysis/2022_13.png,vitg,2022_13.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2023_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2023_11.png,clip,2023_11.txt,train
Cell Reports Physical Science,5_11,Which of the following options best describe the cover story?,"On the cover: Week after week, technology companies unveil new AI tools that increasingly
resemble humans. The activity of humans and scientists is becoming more and more influenced
by AI. Fazio et al. propose a multiscale data-driven strategy for hierarchical physical phenomena that
keeps scientists as main players. Explicit analytical relationships to be easily interpreted
are deduced, enabling a continuous interaction between data modelling and scientific
knowledge. Spider silk is considered as an explicit proof of concept. The cover graphic
was designed by Federica Fazio.",C,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_5.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_5.png,clip,4_5.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_10.png,vitg,2_10.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_11.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_11.png,groundtruth,5_11.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_4.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_4.png,vith,1_4.txt,val
Nature Nanotechnology,19_3,Which of the following options best describe the cover story?,"Water-based nanofabrication
The cover shows an image of water-based micro- and nanopatterned circuits obtained by using silk as a surfactant on a hydrophobic wafer.
See Omenetto
Image: Fiorenzo Omenetto, Silklab. Cover design: Vanitha Selvarajan.",A,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_3.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_3.png,groundtruth,19_3.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_3.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_3.png,clip,18_3.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/17_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/17_8.png,ave_2,17_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/9_9.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/9_9.png,vitg,9_9.txt,train
Accounts of Chemical Research,2024_10,Which of the following options best describe the cover story?,"-cleaning ability can be motivated through meticulous optimization (pruning, fertilizing, and watering), thereby boosting the cycle life and vitality (capacity) of the tree of the Li–S battery. View the article.",D,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_8.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_8.png,vitg,2012_8.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_17.png,clip,2022_17.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_2.png,vith,2015_2.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_10.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_10.png,groundtruth,2024_10.txt,train
Trends in Microbiology,32_5,Which of the following options best describe the cover story?,"The study of the microbiota residing in various tumors (represented in the
cover schematic as planets) has fast become an integral part of oncological research.
However, the low microbial biomass of intratumoral microbiota poses significant
challenges for functional characterization. In this issue, Lu and colleagues propose
a methodological framework integrating multi-modal approaches for intratumoral
microbiota research. These include 16S rRNA gene sequencing (and decontamination
pipelines), single-cell sequencing and culturomics, among others. Image courtesy:
Dr. Liu",A,MAC_Bench/Cell/Cover/Trends in Microbiology/32_5.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_5.png,groundtruth,32_5.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/28_1.png,MAC_Bench/Cell/Cover/Trends in Microbiology/28_1.png,clip,28_1.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/31_5.png,MAC_Bench/Cell/Cover/Trends in Microbiology/31_5.png,vith,31_5.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/27_9.png,MAC_Bench/Cell/Cover/Trends in Microbiology/27_9.png,vitg,27_9.txt,train
Nature Reviews Cardiology,21_9,Which of the following options best describe the cover story?,"Global echocardiography for rheumatic heart disease, inspired by the Evidence-based Guidelines on p250.
Cover design: Vicky Summersby",C,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_1.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_1.png,clip,19_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_8.png,vitg,20_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_9.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_9.png,groundtruth,21_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_10.png,ave_1,19_10.txt,train
NATURE ENERGY,9_1,Which of the following options best describe the cover story?,"Harnessing the strengths of both worlds
High-energy positive electrodes in batteries often face challenges related to low stability and energy efficiency. Huang et al. demonstrate that combining polyanion and rocksalt structures — integrating the characteristics of two primary families of positive electrodes — enhances capacity retention during cycling at high energy densities.
See Huang et al.
Image: Zhongke Yunyan (Shandong) Information Technology Co., Ltd. Cover Design: Thomas Phillips.",C,MAC_Bench/Nature/Cover/NATURE ENERGY/1_11.png,MAC_Bench/Nature/Cover/NATURE ENERGY/1_11.png,vitg,1_11.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/2_9.png,MAC_Bench/Nature/Cover/NATURE ENERGY/2_9.png,clip,2_9.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_1.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/8_6.png,MAC_Bench/Nature/Cover/NATURE ENERGY/8_6.png,vith,8_6.txt,train
Biophysical Journal,124_1,Which of the following options best describe the cover story?,"Cover picture: The image shows a synthetic cell-cell communication pathway in action within developing
Drosophila wing tissue. Blue marks the signal protein on the surface of a population of signal-sending
cells, and where they meet the red receptor protein on the surface of a population
of signal-receiving cells, they induce the expression of the green fluorescent protein
transcriptional output. DOI: 10.1016/j.bpj.2024.11.007.",A,MAC_Bench/Cell/Cover/Biophysical Journal/124_1.png,MAC_Bench/Cell/Cover/Biophysical Journal/124_1.png,groundtruth,124_1.txt,MAC_Bench/Cell/Cover/Biophysical Journal/119_7.png,MAC_Bench/Cell/Cover/Biophysical Journal/119_7.png,clip,119_7.txt,MAC_Bench/Cell/Cover/Biophysical Journal/111_7.png,MAC_Bench/Cell/Cover/Biophysical Journal/111_7.png,vith,111_7.txt,MAC_Bench/Cell/Cover/Biophysical Journal/112_4.png,MAC_Bench/Cell/Cover/Biophysical Journal/112_4.png,vitg,112_4.txt,train
Nature Cell Biology,26_2,Which of the following options best describe the cover story?,"Imaging ovulation
A live imaging approach spatiotemporally dissects mouse ovulation ex vivo.
See Thomas, Marx et al.
Image: Dr. Christopher Thomas, Marseille Developmental Biology Institute (IBDM), CNRS & Aix-Marseille Université. Cover design: Lauren Heslop",D,MAC_Bench/Nature/Cover/Nature Cell Biology/15_11.png,MAC_Bench/Nature/Cover/Nature Cell Biology/15_11.png,vith,15_11.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/8_3.png,MAC_Bench/Nature/Cover/Nature Cell Biology/8_3.png,clip,8_3.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/13_11.png,MAC_Bench/Nature/Cover/Nature Cell Biology/13_11.png,vitg,13_11.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_2.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_2.png,groundtruth,26_2.txt,train
Industrial & Engineering Chemistry Research,2024_14,Which of the following options best describe the cover story?,"extends its gratitude to all reviewers who evaluated manuscripts submitted to the journal in 2023. Special recognition goes to the top 36 reviewers, whose thorough assessments and insightful recommendations significantly enhanced the quality of the submissions.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_4.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_4.png,ave_2,2021_4.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_14.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_47.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_47.png,ave_1,2021_47.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_15.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_15.png,clip,2021_15.txt,train
Trends in Chemistry,7_1,Which of the following options best describe the cover story?,"Polyoxovanadates (POVs) are a versatile class of metal-oxido clusters
with excellent solution, redox and thermal stability, and are particularly noted for
binding
to various peptide and protein targets with various therapeutic outcomes. In their
Forum article in this issue, Merlino and co-workers discuss recent data on the structural
features and binding mechanisms of POVs with proteins, to help better elucidate
structure-property-function correlation. These studies can aid the development of
new
POVs, help to better understand their biological action, suggest new uses for known
structures and break into wider fields like biohybrid materials and energy process
engineering.
Cover image credit: Prof. Antonello Merlino",B,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,vitg,5_9.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/7_1.png,MAC_Bench/Cell/Cover/Trends in Chemistry/7_1.png,groundtruth,7_1.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/2_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/2_7.png,vith,2_7.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/7_2.png,MAC_Bench/Cell/Cover/Trends in Chemistry/7_2.png,clip,7_2.txt,test
Nature Neuroscience,27_10,Which of the following options best describe the cover story?,"Mapping circuits for DBS
Within the enigmatic depths of an aquatic universe, divers use flashlights to reveal the hidden contours of an uncharted seabed that teems with wondrous vegetation. In an analogous exploration, Hollunder et al. describe how invasive brain stimulation delivered to deep-seated brain nuclei may act as a beacon. Using deep brain stimulation (DBS), they show that the frontal cortex can be segregated into distinct circuits that become dysfunctional in four different brain disorders. Their topographical map may shed light on more-precise brain-circuit therapeutics.
See Hollunder, et al.
Image and cover design: Barbara Hollunder. Cover Design: Debbie Maizels.",C,MAC_Bench/Nature/Cover/Nature Neuroscience/7_1.png,MAC_Bench/Nature/Cover/Nature Neuroscience/7_1.png,vith,7_1.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/25_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/25_11.png,vitg,25_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_10.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_10.png,groundtruth,27_10.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/24_10.png,MAC_Bench/Nature/Cover/Nature Neuroscience/24_10.png,clip,24_10.txt,val
Nature Sustainability,7_7,Which of the following options best describe the cover story?,"A smart film for plant growth
Plants are vulnerable to heat and drought stress. Bin Zhu and colleagues present a film design that can manage sunlight to enable reduced temperature, minimized water loss and increased photosynthesis.
See Li et al.
Image and design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Sustainability/4_6.png,MAC_Bench/Nature/Cover/Nature Sustainability/4_6.png,vitg,4_6.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_7.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_7.png,groundtruth,7_7.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_4.png,vith,7_4.txt,MAC_Bench/Nature/Cover/Nature Sustainability/2_3.png,MAC_Bench/Nature/Cover/Nature Sustainability/2_3.png,clip,2_3.txt,train
ACS Sustainable Chemistry & Engineering,2025_6,Which of the following options best describe the cover story?,The CO2 tree highlights the breadth of chemical compounds currently accessible from CO2 to illustrate its potential to serve as a carbon source for the future.,C,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_12.png,ave_2,2020_12.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2022_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2022_2.png,ave_1,2022_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_6.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_7.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_7.png,clip,2025_7.txt,train
Journal of Chemical Theory and Computation,2024_23,Which of the following options best describe the cover story?,"The singlet-triplet (ST) inversion observed in several triangle-shaped organic molecules containing conjugated carbon and nitrogen atoms is an astonishing result. Here we demonstrate that the ST inversion does not require triangle-shaped molecules nor any specific molecular symmetry, but rather a small HOMO-LUMO gap and a small exchange integral between frontier orbitals.",C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,ave_2,2023_16.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_6.png,clip,2022_6.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_23.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_23.png,groundtruth,2024_23.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_18.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_18.png,vith,2023_18.txt,train
Nature Physics,20_8,Which of the following options best describe the cover story?,"Non-classical correlations
Quantum devices need to be linked together in such a way that entanglement can be shared between them. Meesala et al. demonstrate a step towards this goal by developing a transducer capable of generating microwave-optical photon pairs that can be used to share non-classical correlations between an optical link and a superconducting quantum device.
See Meesala et al.
Image: Steven Wood, California Institute of Technology. Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/Nature Physics/19_3.png,MAC_Bench/Nature/Cover/Nature Physics/19_3.png,clip,19_3.txt,MAC_Bench/Nature/Cover/Nature Physics/17_8.png,MAC_Bench/Nature/Cover/Nature Physics/17_8.png,vitg,17_8.txt,MAC_Bench/Nature/Cover/Nature Physics/20_8.png,MAC_Bench/Nature/Cover/Nature Physics/20_8.png,groundtruth,20_8.txt,MAC_Bench/Nature/Cover/Nature Physics/18_8.png,MAC_Bench/Nature/Cover/Nature Physics/18_8.png,vith,18_8.txt,train
Trends in Cell Biology,34_11,Which of the following options best describe the cover story?,"Mitochondria play a crucial role in the regulation of ferroptotic cell
death. They are a major source of ROS, but also produce key metabolites to protect
the cells from lipid peroxidation and oxidative damage. The cover illustrations shows
the metamorphosis of mitochondrial function from supporting cell survival following
oxidative damage to promoting ferroptosis and leading to cardiac damage. Cover
illustration by Sofia Ahola (www.sofiaahola.com).",D,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_11.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_11.png,ave_0,23_11.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_12.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_12.png,clip,26_12.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/33_7.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/33_7.png,vith,33_7.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_11.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_11.png,groundtruth,34_11.txt,train
Nature Reviews Nephrology,20_6,Which of the following options best describe the cover story?,"Kidney disease: a global health priority, inspired by the Consensus Statement on p473.
Cover design: Sam Whitham",C,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,clip,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_12.png,vith,20_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_6.png,groundtruth,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_5.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_5.png,ave_2,19_5.txt,val
One Earth,7_4,Which of the following options best describe the cover story?,"On the cover: This month’s cover features The Role of Carbon Dioxide Removal from the series “Environmental Graphiti – The Art of Climate Change.” This artwork
is based on a figure from the United Nations Emission Gap Report 2017, which illustrates
the emission reductions from conventional mitigation technologies combined with carbon
dioxide removal (the black curve), against a business-as-usual scenario (the blue
curve), to keep global warming below 2°C relative to pre-industrial levels (with at
least 66% chance). Global net emissions levels turn to net zero and afterwards net
negative by the end of this century. Cover by Alisa Singer, http://www.environmentalgraphiti.org/, courtesy of the artist.",B,MAC_Bench/Cell/Cover/One Earth/5_4.png,MAC_Bench/Cell/Cover/One Earth/5_4.png,ave_1,5_4.txt,MAC_Bench/Cell/Cover/One Earth/7_4.png,MAC_Bench/Cell/Cover/One Earth/7_4.png,groundtruth,7_4.txt,MAC_Bench/Cell/Cover/One Earth/4_2.png,MAC_Bench/Cell/Cover/One Earth/4_2.png,vitg,4_2.txt,MAC_Bench/Cell/Cover/One Earth/6_7.png,MAC_Bench/Cell/Cover/One Earth/6_7.png,clip,6_7.txt,train
ACS Sensors,2024_9,Which of the following options best describe the cover story?,"The oxygen-terminated nanocrystalline boron-doped diamond microsensor exhibits high-antifouling properties against protein adsorption and exceptional electrochemical activities, allowing for in vivo monitoring of dopamine dynamics in rat brains and presenting a potential solution for the design of next-generation antifouling neural recording sensors.",A,MAC_Bench/ACS/Cover/ACS Sensors/2024_9.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sensors/2019_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2019_4.png,clip,2019_4.txt,MAC_Bench/ACS/Cover/ACS Sensors/2017_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2017_4.png,vitg,2017_4.txt,MAC_Bench/ACS/Cover/ACS Sensors/2019_8.png,MAC_Bench/ACS/Cover/ACS Sensors/2019_8.png,vith,2019_8.txt,train
NATURE MEDICINE,30_1,Which of the following options best describe the cover story?,"Human Cell Atlas
In this issue, multiple studies from the Human Cell Atlas report findings from human single-cell and spatial genomics datasets of vascular cells, healthy female breast tissues, placentas, and lung tissues from people with fatal COVID-19. The cover depicts these data projected onto a multifaceted lantern. The shapes and colors indicate the myriad cell states in the human body in different organs and tissues, and the diversity of the human population, with unfinished areas representing data still yet to be explored.
See Barnett et al., Bhat-Nakshatri et al., Ounadjela et al. and Nyirenda et al.
Image: Dinithi Sumanaweera, University of Cambridge, and Su Min Suh, SciStories. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/NATURE MEDICINE/27_8.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/27_8.png,vitg,27_8.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_1.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_1.png,groundtruth,30_1.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_10.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_10.png,vith,25_10.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/23_3.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/23_3.png,clip,23_3.txt,train
ACS Materials Au,2024_4,Which of the following options best describe the cover story?,This cover portrays the ability of electron tomography to observe the intricate three-dimensional details of a self-assembled metal nanoparticle superstructure.,D,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,ave_2,2023_2.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_4.png,clip,2022_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_3.png,vith,2022_3.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,groundtruth,2024_4.txt,train
BDJ,238_1,Which of the following options best describe the cover story?,"In this issue
This issue features articles on primary tooth extractions, supervised toothbrushing programmes, and pterygoid implants.

Cover image: Hang in there. An ode to the poor prognosis tooth which has weathered the ages, through thick and thin.
©Pippasha Khan @DrPippa.K",C,MAC_Bench/Nature/Cover/BDJ/238_2.png,MAC_Bench/Nature/Cover/BDJ/238_2.png,vitg,238_2.txt,MAC_Bench/Nature/Cover/BDJ/228_4.png,MAC_Bench/Nature/Cover/BDJ/228_4.png,ave_1,228_4.txt,MAC_Bench/Nature/Cover/BDJ/238_1.png,MAC_Bench/Nature/Cover/BDJ/238_1.png,groundtruth,238_1.txt,MAC_Bench/Nature/Cover/BDJ/230_8.png,MAC_Bench/Nature/Cover/BDJ/230_8.png,clip,230_8.txt,test
Nature Sustainability,8_1,Which of the following options best describe the cover story?,"Sustainable rice farming in South Asia
The overuse of nitrogen fertilizer in the production of rice can have detrimental environmental effects. With a large dataset from more than 31,000 farmer fields in South Asia, Coggins and colleagues identify pathways optimizing nitrogen use efficiency in rice cropping systems across the region.
See Coggins et al.
Image: Arunabh Bhattacharjee / Alamy Stock. Cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/Nature Sustainability/1_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/1_4.png,vitg,1_4.txt,MAC_Bench/Nature/Cover/Nature Sustainability/4_2.png,MAC_Bench/Nature/Cover/Nature Sustainability/4_2.png,vith,4_2.txt,MAC_Bench/Nature/Cover/Nature Sustainability/5_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/5_4.png,clip,5_4.txt,MAC_Bench/Nature/Cover/Nature Sustainability/8_1.png,MAC_Bench/Nature/Cover/Nature Sustainability/8_1.png,groundtruth,8_1.txt,train
Trends in Immunology,45_12,Which of the following options best describe the cover story?,"The image is a photograph of Eptesicus fuscus (big brown bat). A
couple of articles in this issue discuss the importance of better understanding
bat immunity to elucidate bat–human host interactions, extrapolate knowledge
of bat immunity to that of humans, as well as the translational potential of these
comparisons. Mossman and colleagues review the spillover of viruses from bats to
humans and the novel technologies discerning the factors driving virus and host coevolution;
Banerjee and colleagues propose that research in bat immunity can lead
to translational approaches to improve human health. Image credit: Brock Fenton
and Sherri Fenton.",D,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,vitg,39_14.txt,MAC_Bench/Cell/Cover/Trends in Immunology/42_9.png,MAC_Bench/Cell/Cover/Trends in Immunology/42_9.png,vith,42_9.txt,MAC_Bench/Cell/Cover/Trends in Immunology/32_5.png,MAC_Bench/Cell/Cover/Trends in Immunology/32_5.png,clip,32_5.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_12.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_12.png,groundtruth,45_12.txt,train
Nature Chemical Engineering,1_5,Which of the following options best describe the cover story?,"Engineering assembly pathways
Visualizing and manipulating the self-assembly pathways of nanoparticles to form functionalized superstructures remains challenging. Now, Xingchen Ye, Sharon Glotzer and colleagues image the complete self-assembly process of gold nanocubes in situ through liquid-cell transmission electron microscopy. Both molecular dynamics simulations and scaling theory were applied to quantify the interactions between the nanocubes and solvent to enable on-the-fly control of the self-assembly pathways. The cover image shows the self-assembly of gold nanocubes into three distinct superlattices.
See Zhong et al. and Woehl
Image: Ella Maru Studio. Cover design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,groundtruth,1_5.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/2_1.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,vith,1_9.txt,train
Journal of the American Chemical Society,2024_32,Which of the following options best describe the cover story?,"An enzyme-cored spherical nucleic acid nanoplatform (CAT-ecSNA-Cu) used to deliver copper ions for cuproptosis was obtained based on enzyme–nucleic acid coupling and rolling circle amplification techniques. This strategy of enhancing cuproptosis-mediated anti-tumor immune responses by alleviating hypoxia promotes the activation of effector T cells, ultimately leading to long-term immunity against cancer.  View the article.",B,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_8.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_8.png,vitg,2023_8.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_32.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_32.png,groundtruth,2024_32.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_13.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_13.png,clip,2019_13.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_36.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_36.png,ave_2,2019_36.txt,train
Nature Aging,4_10,Which of the following options best describe the cover story?,"Plasma membrane damage induces senescence
In this issue, Kojiro Suda, Yohsuke Moriyama, Nurhanani Razali and colleagues set out, using a genome-wide screen and gene-expression analysis in budding yeast, to better understand the cellular response to plasma membrane damage. The team discover that damage to the plasma membrane can limit replicative lifespan in yeast and induce senescence in human fibroblasts. The cover image shows kintsugi, the traditional Japanese art of repairing broken pottery by mending the cracks with urushi and gold. Kintsugi visibly incorporates the history of an object into its new form and thus transforms it. In this analogy, cell membrane damaged is repaired; however, rather than restoring the cell to its previous form, the new cellular nature is irreversibly changed and distinct from its previous state.
See Suda et al.
Image: Amy Cao. Cover design: Lauren Heslop.",B,MAC_Bench/Nature/Cover/Nature Aging/3_7.png,MAC_Bench/Nature/Cover/Nature Aging/3_7.png,vitg,3_7.txt,MAC_Bench/Nature/Cover/Nature Aging/4_10.png,MAC_Bench/Nature/Cover/Nature Aging/4_10.png,groundtruth,4_10.txt,MAC_Bench/Nature/Cover/Nature Aging/4_4.png,MAC_Bench/Nature/Cover/Nature Aging/4_4.png,clip,4_4.txt,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,vith,1_1.txt,train
Trends in Microbiology,32_2,Which of the following options best describe the cover story?,"Bacteria have repeatedly evolved and repurposed phage machinery to kill
neighbouring bacteria. These bactericidal complexes called tailocins are strain-specific
in
their killing and show promise as targeted antibiotics. In this issue, Drs. Karasov,
Burbano,
and colleagues discuss ways in which tailocins target and kill closely related bacteria
but
avoid self-killing. Evolving the optimal tailocin specificity involves tradeoffs between
broads-pectrum
killing and outer membrane resistance to the environment.
Image courtesy: Daniel Rouhani, Exonscientific",C,MAC_Bench/Cell/Cover/Trends in Microbiology/30_2.png,MAC_Bench/Cell/Cover/Trends in Microbiology/30_2.png,vitg,30_2.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/27_2.png,MAC_Bench/Cell/Cover/Trends in Microbiology/27_2.png,vith,27_2.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_2.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_2.png,groundtruth,32_2.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/28_4.png,MAC_Bench/Cell/Cover/Trends in Microbiology/28_4.png,clip,28_4.txt,train
Industrial & Engineering Chemistry Research,2024_45,Which of the following options best describe the cover story?,Superacid-catalyzed polymers with fully ladder backbones and well-defined micropores demonstrate outstanding performance for advanced membrane gas separations. The micropore architecture and gas separation are regulated through the steric hindrance imposed by the different side groups on chain packing density and rigidity.,A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_45.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_45.png,groundtruth,2024_45.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,vitg,2021_45.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_19.png,clip,2021_19.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_6.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_6.png,vith,2023_6.txt,test
Caner Cell,42_11,Which of the following options best describe the cover story?,"On the cover: Zhou et al. report the results of a phase 3 trial that demonstrates the efficacy and safety of
serplulimab plus chemotherapy as first-line treatment for patients with advanced squamous
non-small-cell lung cancer (sqNSCLC). The cover shows a collage of pathology slices
and lively colors that represent the complexity of the disease but also symbolize
how the results of this ASTRUM-004 study have invigorated research and innovation
in sqNSCLC.",C,MAC_Bench/Cell/Cover/Caner Cell/38_6.png,MAC_Bench/Cell/Cover/Caner Cell/38_6.png,clip,38_6.txt,MAC_Bench/Cell/Cover/Caner Cell/27_1.png,MAC_Bench/Cell/Cover/Caner Cell/27_1.png,vith,27_1.txt,MAC_Bench/Cell/Cover/Caner Cell/42_11.png,MAC_Bench/Cell/Cover/Caner Cell/42_11.png,groundtruth,42_11.txt,MAC_Bench/Cell/Cover/Caner Cell/39_4.png,MAC_Bench/Cell/Cover/Caner Cell/39_4.png,vitg,39_4.txt,train
ACS Chemical Biology,2024_1,Which of the following options best describe the cover story?,"Switchback nucleic acid structures contain right-handed helical half-turns that are laterally arranged to form a globally left-handed structure with parallel strand orientation (set of blocks in the middle) in contrast to conventional duplexes that contain vertically stacked half-turns that form a right-handed structure with antiparallel strands (set of blocks on the right). The cover image was designed by Ella Maru Studio, Inc.",B,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_6.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_6.png,vitg,2015_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_1.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2022_12.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2022_12.png,ave_1,2022_12.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_8.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_8.png,clip,2015_8.txt,train
Nature Reviews Rheumatology,21_1,Which of the following options best describe the cover story?,"Inspired by the Review on p9.
Cover design: Steven Hall",C,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_5.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_5.png,clip,19_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,vith,10_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/21_1.png,groundtruth,21_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/17_1.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/17_1.png,vitg,17_1.txt,train
Nature Physics,20_9,Which of the following options best describe the cover story?,"Material time in a material world
The way in which glassy materials age can be difficult to describe. The concept of material time allows for the description of this physical ageing in a linear way. Multispeckle dynamic light scattering experiments now provide experimental access to material time and show that intensity fluctuations become statistically reversible when referenced in this way.
See Böhmer
IMAGE: Sebastian Keuth. COVER DESIGN: Amie Fernandez",C,MAC_Bench/Nature/Cover/Nature Physics/17_12.png,MAC_Bench/Nature/Cover/Nature Physics/17_12.png,vitg,17_12.txt,MAC_Bench/Nature/Cover/Nature Physics/20_8.png,MAC_Bench/Nature/Cover/Nature Physics/20_8.png,clip,20_8.txt,MAC_Bench/Nature/Cover/Nature Physics/20_9.png,MAC_Bench/Nature/Cover/Nature Physics/20_9.png,groundtruth,20_9.txt,MAC_Bench/Nature/Cover/Nature Physics/19_2.png,MAC_Bench/Nature/Cover/Nature Physics/19_2.png,ave_2,19_2.txt,train
NATURE REVIEWS NEUROSCIENCE,25_1,Which of the following options best describe the cover story?,"‘Neuroscience in natural contexts’, inspired by the Perspective on p809
Cover design: Jennie Vallis",C,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/21_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/21_9.png,vith,21_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_1.png,groundtruth,25_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/21_11.png,vitg,21_11.txt,train
Nature Reviews Cardiology,22_1,Which of the following options best describe the cover story?,"Cardiac sarcomeric proteins, inspired by the Review on p9
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_9.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_9.png,clip,19_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/22_1.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/22_1.png,groundtruth,22_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_12.png,ave_2,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_7.png,vitg,19_7.txt,train
ACS ES&T Air,2024_5,Which of the following options best describe the cover story?,"Ethylene oxide (EtO) is a colorless, flammable, reactive gas commonly used for sterilization and chemical manufacturing that has become a contaminant of concern for the U.S. EPA as a result of an assessment of its toxicity, which found that EtO is more potent than had been previously understood.",A,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_5.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,vitg,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,ave_3,2025_2.txt,test
Journal of the American Chemical Society,2024_15,Which of the following options best describe the cover story?,"Through massive molecular dynamics simulations, it was found that the fluorine domain endows fluorinated ionic liquids ultrahigh solubility of nitrogen. Meanwhile, a theoretical model of fluorine densification energy was also constructed to predict the abnormal solubility of nitrogen based on the microscopic structure of fluorinated ionic liquids.  View the article.",D,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2012_16.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2012_16.png,vitg,2012_16.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_9.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_9.png,clip,2016_9.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_7.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_7.png,ave_1,2010_7.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_15.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_15.png,groundtruth,2024_15.txt,test
Nature Sustainability,7_6,Which of the following options best describe the cover story?,"Urban expansion and local food in Africa
Rapid urbanization affects both local food and ecological systems in Africa. De Vos and colleagues integrate the effects of land-use displacement and dietary shifts associated with urbanization in scenarios of food demand to study the impact of urban expansion on the African environment.
See De Vos et al.
Image: Arnold Mugasha/Shot by mu. Cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/Nature Sustainability/7_12.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_12.png,vitg,7_12.txt,MAC_Bench/Nature/Cover/Nature Sustainability/5_3.png,MAC_Bench/Nature/Cover/Nature Sustainability/5_3.png,clip,5_3.txt,MAC_Bench/Nature/Cover/Nature Sustainability/1_3.png,MAC_Bench/Nature/Cover/Nature Sustainability/1_3.png,vith,1_3.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_6.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_6.png,groundtruth,7_6.txt,test
Bioconjugate Chemistry,2025_1,Which of the following options best describe the cover story?,"by regulating the expression of BBB functional proteins. Wnt-regulated therapeutics, e.g., nanomedicines, could modulate the BBB permeability via regulating the status of the Wnt signaling pathway.",C,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_11.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_11.png,vith,2016_11.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,vitg,2013_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2017_1.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2017_1.png,clip,2017_1.txt,train
Bioconjugate Chemistry,2024_5,Which of the following options best describe the cover story?,"Cytokine biopharmaceuticals are promising anti-cancer therapeutics. However, clinical use has been hampered as a result of early-onset toxicity arising upon the interaction with their receptors in blood. Ideally, cytokine therapeutics would display biological activity only at the tumor site. Here, we review novel strategies that, by acting like a cork on a bottle, achieve “activity on demand",D,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2018_12.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2018_12.png,vith,2018_12.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2021_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2021_2.png,vitg,2021_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2023_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_5.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_5.png,groundtruth,2024_5.txt,train
ACS ES&T Water,2024_10,Which of the following options best describe the cover story?,"‘Applications of Artificial Intelligence, Machine Learning, and Data Analytics in Water Environments’ showcases the many diverse applications of artificial intelligence, machine learning, and data analytics in addressing environmental issues within the broad context of water.",D,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_12.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_12.png,ave_2,2021_12.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_8.png,ave_1,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_10.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_10.png,clip,2022_10.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_10.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_10.png,groundtruth,2024_10.txt,test
Nature Reviews Bioengineering,2_8,Which of the following options best describe the cover story?,"Prosthetic embodiment refers to the incorporation of a prosthesis into one’s sensory and functional body schema, requiring the consideration of a user’s sense of agency and ownership. This may be achieved by engineering bionic limbs that leverage a closed-loop mechanoneural-machine interface to allow bidirectional information transfer between the peripheral nervous system and external assistive devices. See Tony Shu et al.
Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_12.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_12.png,ave_2,2_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_5.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_4.png,ave_1,2_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_8.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_8.png,groundtruth,2_8.txt,train
NATURE GENETICS,56_8,Which of the following options best describe the cover story?,"Liver spatiotemporal transcriptomics
Two studies characterize spatiotemporal transcriptional dynamics during liver homeostasis, cholestatic injury and regeneration in mice.
See Wu et al. and Xu et al.
Image: Shijie Hao. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/NATURE GENETICS/55_9.png,MAC_Bench/Nature/Cover/NATURE GENETICS/55_9.png,ave_0,55_9.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/50_5.png,MAC_Bench/Nature/Cover/NATURE GENETICS/50_5.png,clip,50_5.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_3.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_3.png,vitg,56_3.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_8.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_8.png,groundtruth,56_8.txt,train
Cell Reports Methods,4_2,Which of the following options best describe the cover story?,"On the cover: In this issue, Sit et al. present MEA-NAP, an open-source flexible network analysis pipeline for neuronal 2D
and 3D organoid multielectrode recordings. The cover is an artistic impression of
the development of hub and non-hub roles in microscale neuronal networks using node
cartography. Image credit: Rachael Feord, PhD, and Susanna Mierau, MD, DPhil.",B,MAC_Bench/Cell/Cover/Cell Reports Methods/2_5.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_5.png,vith,2_5.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_2.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_2.png,groundtruth,4_2.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/1_6.png,MAC_Bench/Cell/Cover/Cell Reports Methods/1_6.png,vitg,1_6.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_6.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_6.png,clip,2_6.txt,test
Nature Reviews Neurology,20_10,Which of the following options best describe the cover story?,"Seizures in Alzheimer disease, inspired by the Review on p162.
Cover design: Philip Patenall",B,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_2.png,clip,18_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_10.png,groundtruth,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/17_10.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/17_10.png,vith,17_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,vitg,20_6.txt,test
Precision Chemistry,2024_5,Which of the following options best describe the cover story?,"This cover art for the Special Issue “Precision Chemistry for Two-Dimensional Materials”  was designed by Xiangfeng Duan of the University of California, Los Angeles and coworkers. It illustrates CuxBi2Se3 nanoplates with systematically tunable Cu doping concentrations, doping sites, and electronic properties as a potential material for future electronics.",D,MAC_Bench/ACS/Cover/Precision Chemistry/2024_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_1.png,ave_1,2024_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_9.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,vitg,2024_6.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,groundtruth,2024_5.txt,val
Cell Reports,43_3,Which of the following options best describe the cover story?,"On the cover: Navigating crevasses at night is aided by spatial learning and memory,
which requires forms of synaptic plasticity such as long-term potentiation (LTP).
In this issue of Cell Reports, Rumian et al. describe how the different phases of LTP are mediated by distinct CaMKII functions.
The picture was taken on the slopes of Cotopaxi, an active stratovolcano in Ecuador,
by Ulli Bayer.",C,MAC_Bench/Cell/Cover/Cell Reports/21_11.png,MAC_Bench/Cell/Cover/Cell Reports/21_11.png,vith,21_11.txt,MAC_Bench/Cell/Cover/Cell Reports/4_3.png,MAC_Bench/Cell/Cover/Cell Reports/4_3.png,vitg,4_3.txt,MAC_Bench/Cell/Cover/Cell Reports/43_3.png,MAC_Bench/Cell/Cover/Cell Reports/43_3.png,groundtruth,43_3.txt,MAC_Bench/Cell/Cover/Cell Reports/26_1.png,MAC_Bench/Cell/Cover/Cell Reports/26_1.png,clip,26_1.txt,train
ACS Chemical Neuroscience,2024_5,Which of the following options best describe the cover story?,Interpreting immune cell behavior and signaling is critical to understanding Alzheimer's neuroinflammation. Preventing neurodegeneration is the goal of reorienting attention from Aβ synthesis to immune-mediated clearance. Successfully addressing obstacles such as negative immune reactions might result in notable progress in the field of immunotherapy by enhancing the accuracy of treatment.,D,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_24.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_24.png,vitg,2022_24.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_8.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_20.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_20.png,vith,2024_20.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_5.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_5.png,groundtruth,2024_5.txt,val
NATURE REVIEWS CANCER,24_10,Which of the following options best describe the cover story?,"Mapping landscapes, inspired by the Review on p171
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,clip,23_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_10.png,groundtruth,24_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/18_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/18_12.png,vith,18_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/22_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/22_11.png,vitg,22_11.txt,train
CHEMICAL REVIEWS,2025_2,Which of the following options best describe the cover story?,"The cover illustration depicts the diverse applications of genetic code expansion (GCE) technology. At the center, the core mechanism of GCE is represented, highlighting its role in enabling the incorporation of non-canonical amino acids into proteins. Surrounding this central image are various applications of GCE, showcasing its versatility and potential impact in fields such as synthetic biology, therapeutic development, and molecular engineering. The interconnected elements emphasize how GCE technology bridges fundamental biological processes with innovative practical applications.",B,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_5.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_5.png,clip,2016_5.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_2.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_15.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2019_15.png,vitg,2019_15.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2018_15.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2018_15.png,vith,2018_15.txt,train
BDJ In Practice,37_7,Which of the following options best describe the cover story?,"In this issue...
June's issue of BDJ In Practice leads with a long read on the increase in dental phobia. what could be driving the increase? Plus we take a look at the viability of endodontics on the NHS as well as advice on setting up in practice
Cover illustration by Tim Marrs",B,MAC_Bench/Nature/Cover/BDJ In Practice/34_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/34_2.png,vitg,34_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_7.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_7.png,groundtruth,37_7.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_9.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_9.png,ave_2,35_9.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,clip,36_1.txt,train
Science Signaling,2007_386,Which of the following options best describe the cover story?,"COVER This week features a Perspective on calcium regulation of the permeability of the nuclear pore complex. The image depicts a nuclear pore. [Image: A. Patel and Z. U. A. Chowdhury, University of London, London, UK.]",A,MAC_Bench/Science/Cover/Science Signaling/2007_386.png,MAC_Bench/Science/Cover/Science Signaling/2007_386.png,groundtruth,2007_386.txt,MAC_Bench/Science/Cover/Science Signaling/17_827.png,MAC_Bench/Science/Cover/Science Signaling/17_827.png,vith,17_827.txt,MAC_Bench/Science/Cover/Science Signaling/8_401.png,MAC_Bench/Science/Cover/Science Signaling/8_401.png,clip,8_401.txt,MAC_Bench/Science/Cover/Science Signaling/7_325.png,MAC_Bench/Science/Cover/Science Signaling/7_325.png,vitg,7_325.txt,test
Joule,8_12,Which of the following options best describe the cover story?,"On the cover: In this issue, Ge et al. show that the insulating quartz networks embedded into the natural chalcocite can
block the long-range migration of Cu ions and construct a voltage divider circuit
for realizing excellent electrical stability and thermoelectric performance in the
natural mixed mineral. The cover art shows the natural mineral that can directly convert
temperature gradient to the electricity; the highlighted network structures in the
minerals are the keys to realizing the excellent thermoelectric performance. Image
credit: Dr. Prof. Zhen-Hua Ge.",C,MAC_Bench/Cell/Cover/Joule/8_7.png,MAC_Bench/Cell/Cover/Joule/8_7.png,vith,8_7.txt,MAC_Bench/Cell/Cover/Joule/6_12.png,MAC_Bench/Cell/Cover/Joule/6_12.png,vitg,6_12.txt,MAC_Bench/Cell/Cover/Joule/8_12.png,MAC_Bench/Cell/Cover/Joule/8_12.png,groundtruth,8_12.txt,MAC_Bench/Cell/Cover/Joule/1_1.png,MAC_Bench/Cell/Cover/Joule/1_1.png,clip,1_1.txt,test
ACS Central Science,2024_8,Which of the following options best describe the cover story?,Capsular polysaccharide of Haemophilus influenzae type b bacteria complexed with a human functional monoclonal antibody to gain information on the minimal structural epitope at the atomic level.,A,MAC_Bench/ACS/Cover/ACS Central Science/2024_8.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_11.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_11.png,ave_2,2023_11.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,vitg,2023_6.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_9.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_9.png,clip,2023_9.txt,test
NATURE ENERGY,9_8,Which of the following options best describe the cover story?,"Resilient lines
Hurricane damage leads to power outages and can trigger cascading failures in power grids as they respond to the initial impacts. Stürmer et al. present a dynamic approach to modelling these wind-induced power-line failures that allows them to test the potential effects of line hardening in providing a more resilient power grid.
See Stürmer et al.
Image: Bob Daemmrich / Alamy Stock Photo. Cover design: Thomas Phillips",C,MAC_Bench/Nature/Cover/NATURE ENERGY/5_11.png,MAC_Bench/Nature/Cover/NATURE ENERGY/5_11.png,vitg,5_11.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/7_4.png,MAC_Bench/Nature/Cover/NATURE ENERGY/7_4.png,ave_2,7_4.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_8.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_8.png,groundtruth,9_8.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/6_10.png,MAC_Bench/Nature/Cover/NATURE ENERGY/6_10.png,clip,6_10.txt,train
Cell Reports,43_5,Which of the following options best describe the cover story?,"On the cover: The process of alternative polyadenylation is dynamically regulated
during development and cell fate determination. In this issue, Liu et al. determine the molecular mechanism by which the RNA-binding protein PQBP1 orchestrates
dynamic mRNA-3'UTR changes during neurogenesis. The cover depicts an ancient Chinese
mythical creature, the Vermilion Bird. The short tails represent the short 3'UTRs
in neural stem cells in contrast to the long tails representing extended 3'UTRs in
mature neurons. Concept and artwork: Zi Chao Zhang, Xian Liu, and Xinyu Wang.",D,MAC_Bench/Cell/Cover/Cell Reports/13_8.png,MAC_Bench/Cell/Cover/Cell Reports/13_8.png,clip,13_8.txt,MAC_Bench/Cell/Cover/Cell Reports/4_3.png,MAC_Bench/Cell/Cover/Cell Reports/4_3.png,vitg,4_3.txt,MAC_Bench/Cell/Cover/Cell Reports/14_8.png,MAC_Bench/Cell/Cover/Cell Reports/14_8.png,vith,14_8.txt,MAC_Bench/Cell/Cover/Cell Reports/43_5.png,MAC_Bench/Cell/Cover/Cell Reports/43_5.png,groundtruth,43_5.txt,train
Nature Computational Science,4_10,Which of the following options best describe the cover story?,"The rise of digital twins
Recently, there has been growing interest and enthusiasm in using digital twins to accelerate scientific discovery and to help researchers and stakeholders with critical decision-making tasks. While the industrial and engineering spaces have seen more developments in digital twin technology, multiple other areas of science — from climate sciences to medical and social sciences — have also realized the potential of digital twins for bringing value and innovation to myriad applications. Nevertheless, many challenges still need to be addressed before the research community can bring the promise of digital twins to fruition. This issue presents a Focus in which we highlight the state of the art, challenges and opportunities in the development and use of digital twins across different domains, with the goal of fostering discussion and collaboration within the computational science community regarding this burgeoning field.
See Focus and Editorial
Image: zf L / Moment / Getty Images. Cover design: Alex Wing",A,MAC_Bench/Nature/Cover/Nature Computational Science/4_10.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_10.png,groundtruth,4_10.txt,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,clip,5_1.txt,MAC_Bench/Nature/Cover/Nature Computational Science/2_2.png,MAC_Bench/Nature/Cover/Nature Computational Science/2_2.png,ave_3,2_2.txt,MAC_Bench/Nature/Cover/Nature Computational Science/1_11.png,MAC_Bench/Nature/Cover/Nature Computational Science/1_11.png,ave_2,1_11.txt,train
Nature Astronomy,8_12,Which of the following options best describe the cover story?,"Habitability across geological timescales
Habitability is usually defined for a specific time during a planet’s evolution. But how is that habitability sustained over billions of years? Comparing habitable conditions across different Solar System bodies is key to our understanding of the underlying processes driving long-term habitability.
See Cockell et al.
Image: James Tuttle Keane, Jet Propulsion Laboratory, California Institute of Technology. Cover design: Bethany Vukomanovic.",B,MAC_Bench/Nature/Cover/Nature Astronomy/7_6.png,MAC_Bench/Nature/Cover/Nature Astronomy/7_6.png,ave_3,7_6.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_12.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_12.png,groundtruth,8_12.txt,MAC_Bench/Nature/Cover/Nature Astronomy/5_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/5_2.png,clip,5_2.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_11.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_11.png,ave_2,2_11.txt,train
Science Signaling,2007_390,Which of the following options best describe the cover story?,COVER This week features a Perspective on circadian signaling in the regulation of plant transpiration. [Image: Julie White],B,MAC_Bench/Science/Cover/Science Signaling/4_172.png,MAC_Bench/Science/Cover/Science Signaling/4_172.png,clip,4_172.txt,MAC_Bench/Science/Cover/Science Signaling/2007_390.png,MAC_Bench/Science/Cover/Science Signaling/2007_390.png,groundtruth,2007_390.txt,MAC_Bench/Science/Cover/Science Signaling/1_21.png,MAC_Bench/Science/Cover/Science Signaling/1_21.png,vith,1_21.txt,MAC_Bench/Science/Cover/Science Signaling/9_452.png,MAC_Bench/Science/Cover/Science Signaling/9_452.png,vitg,9_452.txt,train
Nature Structural & Molecular Biology,32_1,Which of the following options best describe the cover story?,"A chromatin loop in plant immunity
Mencia, Arce et al. show that, in Arabidopsis, an inverted-repeat transposon next to the gene that encodes the pathogen receptor EFR forms a rollercoaster-like loop to control chromatin organization, Mencia, Arce et al. show that, in Arabidopsis, an inverted-repeat transposon next to the gene that encodes the pathogen receptor EFR forms a rollercoaster-like loop to control chromatin organization, EFR expression and the plant immune response.EFR expression and the plant immune response.
See Mencia, Arce et al.
Image credit: Yangang Li / TAO Images Limited / Alamy Stock Photo. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,vitg,28_8.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/29_7.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/29_7.png,clip,29_7.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/32_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/32_1.png,groundtruth,32_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_4.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_4.png,vith,25_4.txt,train
Nature Reviews Earth & Environment,5_6,Which of the following options best describe the cover story?,"Degradation and loss of blue carbon ecosystems contributes to climate change, weakens coastal protection and threatens biodiversity. This Perspective outlines the actions required to achieve goals to restore and protect these ecosystems.
Image credit: Vincent Pommeyrol/Getty images. Cover design: Carl Conway",D,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_4.png,vith,2_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_4.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_4.png,vitg,1_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_1.png,clip,5_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_6.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_6.png,groundtruth,5_6.txt,val
Nature Climate Change,14_10,Which of the following options best describe the cover story?,"Boreal–Arctic wetland methane emissions
Boreal–Arctic wetlands are vulnerable to climate change. Writing in this issue, Yuan and colleagues analysed two decades (2002–2021) of methane emissions from this region and show a robust increasing trend, with strong inter-annual variation. This analysis used eddy covariance and chamber observations, and highlights substantial impacts of warming and vegetation activity.
See Yuan et al. and News & Views by Christensen
Image: Jeremy Snyder, Lawrence Berkeley National Laboratory. Cover design: Valentina Monaco",A,MAC_Bench/Nature/Cover/Nature Climate Change/14_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_10.png,groundtruth,14_10.txt,MAC_Bench/Nature/Cover/Nature Climate Change/9_2.png,MAC_Bench/Nature/Cover/Nature Climate Change/9_2.png,ave_1,9_2.txt,MAC_Bench/Nature/Cover/Nature Climate Change/10_1.png,MAC_Bench/Nature/Cover/Nature Climate Change/10_1.png,clip,10_1.txt,MAC_Bench/Nature/Cover/Nature Climate Change/9_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/9_10.png,ave_2,9_10.txt,train
Trends in Parasitology,40_2,Which of the following options best describe the cover story?,"The life cycle of the malaria parasite, Plasmodium falciparum, relies
on tight control of gene expression which is mainly facilitated by the apicomplexan
Apetala2 (ApiAP2) DNA-binding protein family of sequence-specific transcription factors.
In this issue of Trends in Parasitology, Singhal et al. provide an overview of the recent
developments in the functional biology of P. falciparum ApiAP2 proteins, focusing on
new insights into their interactions with transcriptional regulatory complexes in
the
asexual blood stages along with their roles during sexual commitment, development
and
differentiation into mature male and female gametocytes. The cover art depicts a blood
vessel with malaria parasite-infected red blood cells. The zoomed-in image represents
the nucleus of a P. falciparum gametocyte with the AP2 DNA-binding domains of ApiAP2
proteins (purple domains inside white cloud) recruiting the multi-subunit PfSAGA and
PfMORC (orange and cyan domain clouds) chromatin-associated complexes. Image
credit: Dr. Rajat Kumar.",B,MAC_Bench/Cell/Cover/Trends in Parasitology/31_7.png,MAC_Bench/Cell/Cover/Trends in Parasitology/31_7.png,clip,31_7.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_2.png,groundtruth,40_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/28_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/28_2.png,ave_1,28_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,vitg,34_2.txt,test
NATURE REVIEWS IMMUNOLOGY,24_7,Which of the following options best describe the cover story?,"Olfactory Immunology, inspired by the Review on p381.
Cover design: Simon Bradbrook",A,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_7.png,groundtruth,24_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,vitg,18_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_4.png,vith,18_4.txt,train
NATURE REVIEWS GENETICS,25_11,Which of the following options best describe the cover story?,"Inspired by the Review on p83.
Cover design: Patrick Morgan.",C,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_11.png,groundtruth,25_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_8.png,clip,14_8.txt,val
Molecular Plant,17_5,Which of the following options best describe the cover story?,"On the cover: Fertility restorer genes play an important role in three-line hybrid rice breeding.
In this issue, Song et al. show that structural variations of a new fertility restorer
gene, Rf20, are associated with restoration of wild abortive-type cytoplasmic male sterility
in rice. The cover image features rice paddy field for production of three-line hybrid
seeds and the delicate structure of a rice floret with normal (left) and shrunk (right)
anthers that produce fertile and sterile pollens, respectively. As shown in the circle
around rice floret, RF20 gene as well as its copy number variations and environmental temperature that affect
Rf20 gene expression contribute to the fertility restoration ability of rice restorer
lines. Image by: Li Li.",C,MAC_Bench/Cell/Cover/Molecular Plant/16_5.png,MAC_Bench/Cell/Cover/Molecular Plant/16_5.png,clip,16_5.txt,MAC_Bench/Cell/Cover/Molecular Plant/15_9.png,MAC_Bench/Cell/Cover/Molecular Plant/15_9.png,ave_1,15_9.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_5.png,MAC_Bench/Cell/Cover/Molecular Plant/17_5.png,groundtruth,17_5.txt,MAC_Bench/Cell/Cover/Molecular Plant/10_6.png,MAC_Bench/Cell/Cover/Molecular Plant/10_6.png,vith,10_6.txt,train
JACS Au,2024_3,Which of the following options best describe the cover story?,"Featured on this cover is a novel doping strategy, photoexcitation-assisted molecular doping (PE-MD), which is built upon the familiar mechanism of photoinduced electron transfer. The application of PE-MD to the PDPP4T polymer significantly amplifies its doping level, facilitating efficient thermoelectric conversion for clean energy.",C,MAC_Bench/ACS/Cover/JACS Au/2022_5.png,MAC_Bench/ACS/Cover/JACS Au/2022_5.png,ave_3,2022_5.txt,MAC_Bench/ACS/Cover/JACS Au/2023_5.png,MAC_Bench/ACS/Cover/JACS Au/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/JACS Au/2024_3.png,MAC_Bench/ACS/Cover/JACS Au/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/JACS Au/2025_1.png,MAC_Bench/ACS/Cover/JACS Au/2025_1.png,clip,2025_1.txt,train
Trends in Parasitology,40_7,Which of the following options best describe the cover story?,"Transgenesis emerges as a promising approach for combating malaria
by targeting the parasite in the mosquito vectors. Through genome editing tools,
researchers have managed to generate genetically engineered mosquitoes that exhibit
significant resistance to the malaria parasites. In this issue of Trends in Parasitology, Kefi
et al. review the current literature of the available transgenic methodologies to generate
Plasmodium-refractory Anopheles vectors and discuss both advances and challenges
to be overcome for their practical application. The cover image shows a transgenic
mosquito expressing the GFP reporter gene (green color) under the 3XP3 promoter that
drives the transgene expression in the optic nerves and the eyes. Image credit: Yuemei
Dong (Johns Hopkins Bloomberg School of Public Health).",C,MAC_Bench/Cell/Cover/Trends in Parasitology/36_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/36_2.png,vith,36_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,vitg,34_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_7.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_7.png,groundtruth,40_7.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/38_12.png,MAC_Bench/Cell/Cover/Trends in Parasitology/38_12.png,clip,38_12.txt,train
NATURE REVIEWS GENETICS,25_6,Which of the following options best describe the cover story?,"Inspired by the Reviews on p460 and p476
Cover design: Patrick Morgan",B,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/13_4.png,vitg,13_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_6.png,groundtruth,25_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/24_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/24_1.png,clip,24_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,train
Science Advances,11_5,Which of the following options best describe the cover story?,"ONLINE COVER A polar bear rolling in snow. Polar bears are the only Arctic land mammal that dives into water to hunt, but their fur is typically free of ice. Carolan et al. investigated the anti-icing properties of polar bear fur and found that the low ice accumulation is a consequence of fur sebum, or hair grease. These findings could have potential applications in developing anti-icing surface coatings. Credit: Konrad Wothe / Minden",B,MAC_Bench/Science/Cover/Science Advances/9_45.png,MAC_Bench/Science/Cover/Science Advances/9_45.png,clip,9_45.txt,MAC_Bench/Science/Cover/Science Advances/11_5.png,MAC_Bench/Science/Cover/Science Advances/11_5.png,groundtruth,11_5.txt,MAC_Bench/Science/Cover/Science Advances/10_49.png,MAC_Bench/Science/Cover/Science Advances/10_49.png,ave_2,10_49.txt,MAC_Bench/Science/Cover/Science Advances/10_3.png,MAC_Bench/Science/Cover/Science Advances/10_3.png,ave_3,10_3.txt,train
Journal of the American Chemical Society,2024_47,Which of the following options best describe the cover story?,LiFePO4–Li,B,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_51.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_51.png,vitg,2017_51.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_47.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_47.png,groundtruth,2024_47.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_28.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_28.png,vith,2010_28.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_25.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_25.png,clip,2023_25.txt,train
Nature Catalysis,7_9,Which of the following options best describe the cover story?,"Decarboxylating malonyl-CoA
Acetyl-CoA carboxylation is the canonical route for endogenous malonyl-CoA formation in cells. Now, Li et al. report a non-carboxylative malonyl-CoA pathway, independent of acetyl-CoA. This enables the biosynthesis of multiple malonyl-CoA-derived natural products, also in multiple cellular hosts.
See Li et al.
Image: Jian Li, Shanghai Jiao Tong University. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/Nature Catalysis/7_9.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_9.png,groundtruth,7_9.txt,MAC_Bench/Nature/Cover/Nature Catalysis/4_1.png,MAC_Bench/Nature/Cover/Nature Catalysis/4_1.png,vith,4_1.txt,MAC_Bench/Nature/Cover/Nature Catalysis/4_9.png,MAC_Bench/Nature/Cover/Nature Catalysis/4_9.png,vitg,4_9.txt,MAC_Bench/Nature/Cover/Nature Catalysis/5_9.png,MAC_Bench/Nature/Cover/Nature Catalysis/5_9.png,clip,5_9.txt,train
Environment & Health,2024_7,Which of the following options best describe the cover story?,", the model organism zebrafish exhibits an inflammatory response.",C,MAC_Bench/ACS/Cover/Environment & Health/2023_3.png,MAC_Bench/ACS/Cover/Environment & Health/2023_3.png,ave_2,2023_3.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_10.png,MAC_Bench/ACS/Cover/Environment & Health/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,clip,2024_9.txt,train
ACS Polymers Au,2024_6,Which of the following options best describe the cover story?,We highlight the “rock-like” nature of our hybrid composites obtained from covalently-linked recycled polyols obtained from post-industry use polyurethane materials and inorganic aluminosilicates.,D,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,ave_2,2023_6.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2021_1.png,clip,2021_1.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2021_2.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2021_2.png,vitg,2021_2.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_6.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_6.png,groundtruth,2024_6.txt,val
Trends in Endocrinology & Metabolism,35_4,Which of the following options best describe the cover story?,"Selenium is an essential trace element associated with both beneficial
and detrimental health effects. This month, Schomburg and colleagues (pp. 781–792)
review the current evidence suggesting a sexual dimorphism in the relationship
between selenium and diabetes, as high blood concentrations of this element have
been associated with an increased risk in men but a decreased risk in women,
particularly for gestational diabetes mellitus during pregnancy. The cover picture
highlights the fascinating interaction between selenium, diabetes and sex. Selenium
is
named after the Greek goddess of the moon and is depicted accordingly. She shines
favourably on women when it comes to protection from disease, particularly the risk
of gestational diabetes, while too much exposure could pose an additional diabetes
risk for sweet-toothed men. Cover credit: Katja May.",B,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/28_3.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/28_3.png,vith,28_3.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_4.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_4.png,groundtruth,35_4.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_5.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_5.png,vitg,33_5.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_3.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_3.png,clip,33_3.txt,train
ACS Sustainable Chemistry & Engineering,2025_4,Which of the following options best describe the cover story?,"The potassium sulfate process for refining spodumene concentrate to lithium chemicals produces high value byproducts, potash alum and leucite fertilizer, in contract to the conventional technology that yields low-value sodium sulfate and no-value hydrogen aluminosilicate.",C,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2024_13.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2024_13.png,ave_1,2024_13.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_5.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_5.png,clip,2025_5.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_4.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2023_35.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2023_35.png,ave_2,2023_35.txt,train
Journal of the American Chemical Society,2024_42,Which of the following options best describe the cover story?,free stream exits the mountain.,B,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_11.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_11.png,clip,2018_11.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_42.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_42.png,groundtruth,2024_42.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_46.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_46.png,vith,2009_46.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2022_44.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2022_44.png,vitg,2022_44.txt,train
Developmental Cell,59_20,Which of the following options best describe the cover story?,"On the cover: The image shows a human renal organoid derived from induced pluripotent
stem cells at day 14 of the protocol. The convoluted epithelial tube of the forming
nephron is visible, with the apical side labeled by staining for ZO1 (in yellow) and
the basal side of the cells labeled by staining for integrin beta-1 (in magenta).
Nuclei of both epithelial and surrounding mesenchymal cells are labeled by DAPI staining
(in blue), and cells fated to become nephrons are labeled by staining for the transcription
factor HNF1B. To learn more about mesenchymal-to-epithelial transition in renal development,
see Ng-Blichfeldt et al. Image credit: John-Poul Ng-Blichfeldt.",B,MAC_Bench/Cell/Cover/Developmental Cell/20_6.png,MAC_Bench/Cell/Cover/Developmental Cell/20_6.png,ave_1,20_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,groundtruth,59_20.txt,MAC_Bench/Cell/Cover/Developmental Cell/22_1.png,MAC_Bench/Cell/Cover/Developmental Cell/22_1.png,clip,22_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/37_6.png,MAC_Bench/Cell/Cover/Developmental Cell/37_6.png,vitg,37_6.txt,train
Cell Genomics,4_10,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Lin et al. use baboons to characterize molecular effects of a high-cholesterol, high-fat diet
and its interactions with genetic variation on gene expression. The cover depicts
a captive baboon from the pedigreed colony from Southwest National Primate Research
Center (SNPRC). The photo is provided courtesy of SNPRC at Texas Biomedical Research
Institute.",C,MAC_Bench/Cell/Cover/Cell Genomics/2_1.png,MAC_Bench/Cell/Cover/Cell Genomics/2_1.png,ave_3,2_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_7.png,MAC_Bench/Cell/Cover/Cell Genomics/2_7.png,clip,2_7.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_10.png,MAC_Bench/Cell/Cover/Cell Genomics/4_10.png,groundtruth,4_10.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_9.png,MAC_Bench/Cell/Cover/Cell Genomics/4_9.png,ave_2,4_9.txt,train
The Journal of Physical Chemistry C,2025_4,Which of the following options best describe the cover story?,"In this perspective, we discuss how one can correlate computational catalysis results with experimental techniques, such as calorimetry, temperature-programmed desorption, infrared spectroscopy, and XPS measurements. For example, configuration space mapping for the alloying of Ru into Fe(100) through a lattice gas model enables the construction of coverage-dependent microkinetic models involving oxygenated aromatics and identifies a catalytically relevant ground state structure. This structure features Fe (gold spheres) alloyed with Ru at the surface (pink spheres) and Ru at subsurface sites (large red spheres). The lattice gas model accounts for 2-body and 3-body interactions (examples shown), as well as higher-order interactions, which are quantified using first-principles calculations. The lateral interactions between oxygenated aromatics can also be quantified within a mean-field model, allowing for the correlation with core-level binding energy shifts observed in XPS measurements.",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_6.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_6.png,clip,2025_6.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_4.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2018_21.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2018_21.png,vitg,2018_21.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2019_20.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2019_20.png,vith,2019_20.txt,test
NATURE GENETICS,56_12,Which of the following options best describe the cover story?,"Banana genome evolution
Genome assemblies of triploid Cavendish and Gros Michel bananas reveal the origins, disease resistance and fruit-ripening mechanisms of the banana cultivars.
See Li et al.
Image: Aleksandr Zubkov/Moment/Getty. Cover design: Tulsi Voralia.",A,MAC_Bench/Nature/Cover/NATURE GENETICS/56_12.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_12.png,groundtruth,56_12.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_2.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_2.png,vitg,49_2.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/54_8.png,MAC_Bench/Nature/Cover/NATURE GENETICS/54_8.png,clip,54_8.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_6.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_6.png,ave_1,49_6.txt,train
Nature Reviews Nephrology,20_10,Which of the following options best describe the cover story?,"Advancing equitable access to care, inspired by the Comment articles for World Kidney Day starting on p147.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_12.png,ave_1,20_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_10.png,groundtruth,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,clip,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_4.png,ave_2,20_4.txt,train
ACS Chemical Neuroscience,2024_1,Which of the following options best describe the cover story?,"A gold-star-coated aluminum substrate-based SERS immunoassay platform for the selective detection of blood-based biomarkers Aβ40, Aβ42, p-Tau, and t-Tau of Alzheimer’s disease (AD). SERS spectral data augmented by the machine learning technique yielded high sensitivity of the order of an attomolar concentration of the biomarkers and successfully differentiated between controls and patients with mild cognitive impairment and AD. The image was generated with the assistance of ChatGPT, powered by OpenAI.",D,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_1.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_1.png,vitg,2022_1.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,vith,2024_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_9.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_9.png,clip,2017_9.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_1.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_1.png,groundtruth,2024_1.txt,train
Science Signaling,2007_378,Which of the following options best describe the cover story?,COVER This week features a Protocol that describes software used to explore how polarization in membrane lipids occurs in response to chemotactic stimuli. The image depicts the simulated PIP3 concentration when a cell is experiencing chemotactic stimuli from two point sources at opposing poles.,A,MAC_Bench/Science/Cover/Science Signaling/2007_378.png,MAC_Bench/Science/Cover/Science Signaling/2007_378.png,groundtruth,2007_378.txt,MAC_Bench/Science/Cover/Science Signaling/2_61.png,MAC_Bench/Science/Cover/Science Signaling/2_61.png,ave_1,2_61.txt,MAC_Bench/Science/Cover/Science Signaling/1_46.png,MAC_Bench/Science/Cover/Science Signaling/1_46.png,vitg,1_46.txt,MAC_Bench/Science/Cover/Science Signaling/1_34.png,MAC_Bench/Science/Cover/Science Signaling/1_34.png,clip,1_34.txt,train
Nature Reviews Physics,6_9,Which of the following options best describe the cover story?,"The cover of this issue illustrates living human cancer cells and tissues. See Massey et al.
Image: Alexander Cartagena-Rivera, National Institutes of Health, US. Cover design: Susanne Harris.",D,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_8.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_8.png,vitg,4_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_12.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_12.png,clip,1_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/2_7.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/2_7.png,ave_2,2_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_9.png,groundtruth,6_9.txt,test
ACS Infectious Diseases,2024_1,Which of the following options best describe the cover story?,Mouse liver tissue stained with DAPI to visualize nuclei and Nile red to visualize lipids and lipid droplets.,A,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_1.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_6.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_6.png,ave_3,2020_6.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_11.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_11.png,clip,2024_11.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_2.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_2.png,vitg,2024_2.txt,train
NATURE GENETICS,57_1,Which of the following options best describe the cover story?,"Blood DNA virome in COVID-19 and autoimmune diseases
Analysis of the blood DNA virome in patients with COVID-19 and autoimmune diseases associates endogenous HHV-6 and high anellovirus load with increased disease risk.
See Sasa et al.
Image: Itsuki Kitayama, STUDIO BIUM. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/NATURE GENETICS/50_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/50_1.png,ave_0,50_1.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_1.png,clip,56_1.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/54_3.png,MAC_Bench/Nature/Cover/NATURE GENETICS/54_3.png,vitg,54_3.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/57_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/57_1.png,groundtruth,57_1.txt,train
Science Advances,11_2,Which of the following options best describe the cover story?,"ONLINE COVER Artistic rendering of rosette colonies and solitary cells of the choanoflagellate Salpingoeca rosetta undergoing signaling events. Choanoflagellates are the closest living relatives of animals. Colgren et al. identified communication amongst the cells of S. rosetta colonies. This communication regulates shape and ciliary beating across the rosette. Understanding how information flows between cells in choanoflagellate colonies provides key insights into early animal evolution. Credit: Davis Laundon, Ella Maru Studio and Kate Zvorykina (Ella Maru Studio, Inc.)",B,MAC_Bench/Science/Cover/Science Advances/9_24.png,MAC_Bench/Science/Cover/Science Advances/9_24.png,vitg,9_24.txt,MAC_Bench/Science/Cover/Science Advances/11_2.png,MAC_Bench/Science/Cover/Science Advances/11_2.png,groundtruth,11_2.txt,MAC_Bench/Science/Cover/Science Advances/9_14.png,MAC_Bench/Science/Cover/Science Advances/9_14.png,vith,9_14.txt,MAC_Bench/Science/Cover/Science Advances/9_26.png,MAC_Bench/Science/Cover/Science Advances/9_26.png,clip,9_26.txt,val
Cell Reports Physical Science,5_12,Which of the following options best describe the cover story?,"On the cover: The study by Xiang et al. primarily focuses on data-driven lithium-ion battery degradation models. The cover
image incorporates an electric vehicle, a battery, and neurons representing deep learning,
indicating our use of a semi-supervised deep-learning method to empower the aging
modeling of lithium-ion batteries in electric vehicles. The gradient colors of the
battery imply its aging process. The authors would like to express gratitude to Qinxin
Li for creating the image.",D,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_12.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_12.png,vith,3_12.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_1.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_1.png,vitg,1_1.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_5.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_5.png,clip,3_5.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_12.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_12.png,groundtruth,5_12.txt,train
Trends in Cell Biology,34_8,Which of the following options best describe the cover story?,"In ancient China, families would hold coronations for children upon reaching adulthood.
Similarly, eukaryotic mature RNA features a canonical m7G cap at the 5’-end. In contrast, the noncanonical NAD+ cap is added through ab initio capping and is vulnerable to degradation through deNADding and deNMNning. These NAD+-capped RNAs are spliced and polyadenylated similar to m7G-RNAs, and are enriched
in mitochondria. In this issue, Ma et al. outline the detection, sequencing methods, and functional significance of NAD+-capped RNAs on pages 355–359. Cover image by Yong Chen from Riblab workshop.",B,MAC_Bench/Cell/Cover/Trends in Cell Biology/30_8.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/30_8.png,vitg,30_8.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_8.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_8.png,groundtruth,34_8.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/25_3.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/25_3.png,vith,25_3.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_1.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_1.png,clip,29_1.txt,test
Accounts of Chemical Research,2024_23,Which of the following options best describe the cover story?,Artist depiction of an actively translating ribosome. Translation activity of medicinal mRNA was shown to be enhanced by modified nucleosides such as 1-methylpseudouridine. Cover art by Mark Helm.,A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_23.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_23.png,groundtruth,2024_23.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_16.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_16.png,vitg,2021_16.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2011_1.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2011_1.png,clip,2011_1.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_21.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_21.png,ave_1,2024_21.txt,test
Nature Plants,10_6,Which of the following options best describe the cover story?,"Drying out without dying out
Tolerance to desiccation has evolved many times in different plant groups in response to arid environments. Despite multiple evolutionary origins within the grass family, the mechanisms of desiccation tolerance have converged on a small number of common genes and metabolic pathways.
See Marks et al.
Image: Dr Rose Marks. Cover design: Erin Dewalt",A,MAC_Bench/Nature/Cover/Nature Plants/10_6.png,MAC_Bench/Nature/Cover/Nature Plants/10_6.png,groundtruth,10_6.txt,MAC_Bench/Nature/Cover/Nature Plants/7_8.png,MAC_Bench/Nature/Cover/Nature Plants/7_8.png,vitg,7_8.txt,MAC_Bench/Nature/Cover/Nature Plants/5_8.png,MAC_Bench/Nature/Cover/Nature Plants/5_8.png,ave_1,5_8.txt,MAC_Bench/Nature/Cover/Nature Plants/5_6.png,MAC_Bench/Nature/Cover/Nature Plants/5_6.png,clip,5_6.txt,val
ACS Central Science,2024_12,Which of the following options best describe the cover story?,We report the first genetic-encoded photocatalysis method for spatially restricted optochemical modulation of neurons. The cell-type-specific small molecule release dissects an anti-itch signaling mechanism in live mice.,D,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,ave_3,2023_6.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_8.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_10.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_10.png,vitg,2023_10.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_12.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_12.png,groundtruth,2024_12.txt,test
ACS Polymers Au,2024_2,Which of the following options best describe the cover story?,"The cover illustrates various topographical features in nanoconfined polymer thin films, arising from mechano-rheological responses, such as wrinkles, capillary leveling, particle tracking, dewetting hole growth, bubble inflation, and wetting ridges. Due to the extremely low thickness of polymer films, such unconventional characterization methods are imperative, and their efficacy has been demonstrated successfully.",A,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2025_1.png,ave_1,2025_1.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_1.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_1.png,ave_2,2023_1.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,clip,2023_4.txt,train
Macromolecules,2024_1,Which of the following options best describe the cover story?,"The molecular origin of the glassy dynamics associated with the gas-barrier properties, the crystallization kinetics, and the phase behavior of poly(ethylene 2,5-furanoate) (PEF) are explored by employing pressure in addition to temperature.  View the article.",B,MAC_Bench/ACS/Cover/Macromolecules/2011_22.png,MAC_Bench/ACS/Cover/Macromolecules/2011_22.png,ave_2,2011_22.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_1.png,MAC_Bench/ACS/Cover/Macromolecules/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Macromolecules/2018_23.png,MAC_Bench/ACS/Cover/Macromolecules/2018_23.png,clip,2018_23.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_23.png,MAC_Bench/ACS/Cover/Macromolecules/2014_23.png,vitg,2014_23.txt,val
Nature Climate Change,14_2,Which of the following options best describe the cover story?,"Human causes and costs of wildfire
The impacts of climate change on wildfire occurrence and intensity have received increasing attention. Lampe and colleagues show that while other human impacts led to burnt area reduction over time, these actions have masked the contribution of climate change in increasing global burned area and increasing probability of months with high burning. Park and colleagues combine fire–vegetation models with a chemical transport model and health risk assessment framework to show that human mortality from fire fine particulate matter is increasingly attributable to climate change.
See Burton et al., Park et al. and Research Briefing Lampe
Image: Patrick Orton / Cavan / Getty. Cover design: Vanitha Selvarajan",A,MAC_Bench/Nature/Cover/Nature Climate Change/14_2.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_2.png,groundtruth,14_2.txt,MAC_Bench/Nature/Cover/Nature Climate Change/11_8.png,MAC_Bench/Nature/Cover/Nature Climate Change/11_8.png,ave_2,11_8.txt,MAC_Bench/Nature/Cover/Nature Climate Change/8_3.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_3.png,vith,8_3.txt,MAC_Bench/Nature/Cover/Nature Climate Change/10_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/10_10.png,clip,10_10.txt,val
Joule,9_1,Which of the following options best describe the cover story?,"On the cover: In this cover image, Chen et al. present the conceptual design of a new electro-biodiesel platform that converts CO2 into biodiesel by integrating electrocatalysis and microbial bioconversion. The image
illustrates the integrated electro-biodiesel conversion process, where electrocatalytic
reactors convert CO2 into biocompatible C2 intermediates, which are then upgraded into biodiesel precursors
through efficient microbial fermentation. The process flow is shown by the bright
pathway. The transparent container at the center symbolizes the final diesel product.
The image highlights the advancement of an efficient and economic electro-biodiesel
route through the co-design of microbes and catalysts, opening new avenues for sustainable
CO2 conversion. Artist: Yu Zhang (@CYANTIFICA).",A,MAC_Bench/Cell/Cover/Joule/9_1.png,MAC_Bench/Cell/Cover/Joule/9_1.png,groundtruth,9_1.txt,MAC_Bench/Cell/Cover/Joule/6_11.png,MAC_Bench/Cell/Cover/Joule/6_11.png,vitg,6_11.txt,MAC_Bench/Cell/Cover/Joule/4_2.png,MAC_Bench/Cell/Cover/Joule/4_2.png,clip,4_2.txt,MAC_Bench/Cell/Cover/Joule/8_7.png,MAC_Bench/Cell/Cover/Joule/8_7.png,vith,8_7.txt,train
Nature Photonics,18_12,Which of the following options best describe the cover story?,"On-chip optical logic
On-chip optoelectronic logic gates that operate in the telecom wavelength band are constructed by integrating multiple silicon waveguides with black phosphorus.
See He et al.
Image: Weida Hu, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences. Cover Design: Bethany Vukomanovic.",D,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,clip,16_12.txt,MAC_Bench/Nature/Cover/Nature Photonics/7_1.png,MAC_Bench/Nature/Cover/Nature Photonics/7_1.png,vitg,7_1.txt,MAC_Bench/Nature/Cover/Nature Photonics/11_3.png,MAC_Bench/Nature/Cover/Nature Photonics/11_3.png,vith,11_3.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_12.png,MAC_Bench/Nature/Cover/Nature Photonics/18_12.png,groundtruth,18_12.txt,train
Nature Climate Change,14_8,Which of the following options best describe the cover story?,"Focusing on human health
The human cost of climate change is already visible as adverse impacts on diverse aspects of human health. In this issue, and in an online focus, we include primary research, as well as interview, feature and opinion pieces, that highlight the effects of climate change on human morbidity and mortality, and urge for rapid action.
See Editorial and Online collection
Image and cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Climate Change/8_9.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_9.png,vitg,8_9.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_8.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_8.png,groundtruth,14_8.txt,MAC_Bench/Nature/Cover/Nature Climate Change/7_1.png,MAC_Bench/Nature/Cover/Nature Climate Change/7_1.png,clip,7_1.txt,MAC_Bench/Nature/Cover/Nature Climate Change/10_5.png,MAC_Bench/Nature/Cover/Nature Climate Change/10_5.png,ave_2,10_5.txt,train
Nature Cancer,5_1,Which of the following options best describe the cover story?,"2024 in Review
This month we present a dedicated issue, Focus on 2024 in Review, that includes news, analysis and comment pieces on the most exciting advances and biggest challenges of the past year, together with a selection of the primary research articles published in Nature Cancer and elsewhere over the past 12 months.
See our December Editorial and associated Focus content.
Image: Ernie Janes / Alamy Stock Photo. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Cancer/3_1.png,MAC_Bench/Nature/Cover/Nature Cancer/3_1.png,ave_2,3_1.txt,MAC_Bench/Nature/Cover/Nature Cancer/2_1.png,MAC_Bench/Nature/Cover/Nature Cancer/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_1.png,MAC_Bench/Nature/Cover/Nature Cancer/5_1.png,groundtruth,5_1.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_1.png,MAC_Bench/Nature/Cover/Nature Cancer/4_1.png,ave_3,4_1.txt,train
Trends in Cancer,10_11,Which of the following options best describe the cover story?,"Advancements in early cancer detection are key to improved patient
outcome and survival. Recent developments in using circulating tumor DNA (ctDNA)
are under development for the detection of specific cancers. In this issue, Zhang
et al.
propose the use of multi-cancer early detection (MCED) assays, based on circulating
cell-free DNA (cfDNA), for the sensitive detection and accurate localization of multiple
cancer types. The cover depicts a dolphin (MCED) using its echolocation system to
detect and locate the target fish (ctDNA) in a wide range of fishes (cfDNA) in the
deep
sea (blood). Dolphins are very clever and have always been regarded as friends of
humans, and their echolocation system is analogous to using the MCED assay to detect
ctDNA and locate the TOO of cancers. (Headline: Sonar Detective: Finding the target
fish). Image is created by Lei Chen & Guoyan Wang in Soochow University.",B,MAC_Bench/Cell/Cover/Trends in Cancer/2_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/2_6.png,clip,2_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_11.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_11.png,groundtruth,10_11.txt,MAC_Bench/Cell/Cover/Trends in Cancer/4_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_6.png,vith,4_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/2_10.png,MAC_Bench/Cell/Cover/Trends in Cancer/2_10.png,vitg,2_10.txt,test
The Journal of Physical Chemistry A,2025_8,Which of the following options best describe the cover story?,"Collage of artwork from recent issues of J. Phys. Chem. A. Background: Impact of Halogen Termination and Chain Length on π-Electron Conjugation and Vibrational Properties of Halogen-Terminated Polyynes (J. Phys. Chem. A 2024, 128 (14), 2703–2716. DOI:",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_46.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_46.png,vith,2024_46.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_8.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_8.png,groundtruth,2025_8.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2022_44.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2022_44.png,vitg,2022_44.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_32.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_32.png,clip,2024_32.txt,train
Science Translational Medicine,17_784,Which of the following options best describe the cover story?,"ONLINE COVER The Bacteria Behind Lung Rejection. The cover illustration shows two transplanted lungs, one healthy and tolerated by the recipient (left), the other infected by Pseudomonas aeruginosa (light orange), leading to formation of donor-specific antibodies (blue) and antibody-mediated rejection (right), ultimately resulting in lung allograft failure. Liao et al. showed that P. aeruginosa infection was associated with increased risk of antibody-mediated rejection in a small retrospective study of lung transplant recipients and elucidated the mechanism by which P. aeruginosa induced antibody-mediated rejection in mouse orthotopic lung transplant models. A Focus by Guerrero-Fonseca and Yipp explains how this work challenges the conventional view of the development of antibody-mediated rejection and highlights further implications for the clinic. Credit: A. Mastin/Science Translational Medicine",C,MAC_Bench/Science/Cover/Science Translational Medicine/5_174.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_174.png,vitg,5_174.txt,MAC_Bench/Science/Cover/Science Translational Medicine/1_3.png,MAC_Bench/Science/Cover/Science Translational Medicine/1_3.png,clip,1_3.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_784.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_784.png,groundtruth,17_784.txt,MAC_Bench/Science/Cover/Science Translational Medicine/3_78.png,MAC_Bench/Science/Cover/Science Translational Medicine/3_78.png,vith,3_78.txt,train
Cancer Cell,42_4,Which of the following options best describe the cover story?,"On the cover: Watson et al. integrate multi-omics approaches to investigate how the glioblastoma microenvironment
responds to different treatment interventions and discover how treatment-associated
fibrosis can protect surviving tumor cells and promote eventual recurrence. This four-part
image depicts a mouse glioblastoma with renderings of high-dimensional imaging, single-cell
RNA sequencing, mass spectrometry proteomic analysis, and spatial transcriptomics,
respectively in clockwise sequence. Credit: Spencer Watson, Anoek Zomer, and Johanna
Joyce.",A,MAC_Bench/Cell/Cover/Cancer Cell/42_4.png,MAC_Bench/Cell/Cover/Cancer Cell/42_4.png,groundtruth,42_4.txt,MAC_Bench/Cell/Cover/Cancer Cell/28_4.png,MAC_Bench/Cell/Cover/Cancer Cell/28_4.png,vitg,28_4.txt,MAC_Bench/Cell/Cover/Cancer Cell/35_2.png,MAC_Bench/Cell/Cover/Cancer Cell/35_2.png,vith,35_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/30_1.png,MAC_Bench/Cell/Cover/Cancer Cell/30_1.png,clip,30_1.txt,train
The Journal of Physical Chemistry A,2025_4,Which of the following options best describe the cover story?,Kinetics of the thermal isomerization of cyclopropane to propene: evaluation of the biradical and carbene reaction channels across wide temperature and pressure ranges.,C,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2019_30.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2019_30.png,vith,2019_30.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2010_39.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2010_39.png,vitg,2010_39.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_4.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2013_4.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2013_4.png,clip,2013_4.txt,train
Nature Reviews Endocrinology,20_12,Which of the following options best describe the cover story?,"The ageing thyroid, inspired by the Review on p5.
Cover design: Jennie Vallis",A,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_12.png,groundtruth,20_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/10_6.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/10_6.png,ave_2,10_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_4.png,clip,20_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/15_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/15_4.png,ave_1,15_4.txt,val
Trends in Parasitology,40_4,Which of the following options best describe the cover story?,"The fate of Leishmania parasites in mammalian hosts is determined by
the tissue microenvironment and the highly diverse organic and inorganic metabolic
and micro milieu factors at the site of infection, for which Bogdan et al. coined the term
immunomicrotope. In this issue of Trends in Parasitology, they review important cellular
and soluble components of the immunomicrotope in cutaneous and visceral leishmaniasis
and highlight critical processes of parasite control and long-term persistence. The
oil-on-canvas
painting “Circles in a Circle” (1923) by the famous Russian artist Vasily Kandinsky
(1866–1944), which reflects his art-theoretical ideas about forms and colours, can
be
interpreted as a perfect illustration of the complexity of the immunomicrotope, showing,
e.g., different immune cells, intracellular Leishmania amastigotes, cytokines, metabolites,
extracellular matrix fibres, and blood vessels at the encircled site of infection.
Image
credit: The Louise and Walter Arensberg Collection, 1950.",D,MAC_Bench/Cell/Cover/Trends in Parasitology/35_10.png,MAC_Bench/Cell/Cover/Trends in Parasitology/35_10.png,vith,35_10.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,vitg,34_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/37_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/37_2.png,clip,37_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_4.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_4.png,groundtruth,40_4.txt,test
Nature Astronomy,8_2,Which of the following options best describe the cover story?,"Episodic resonance locking guides planet–star coevolution
Stellar seismology couples with planet migration to excite a series of resonance locks that affect the orbital evolution of planets, especially ‘dormant migrating giants’ that can become hot Jupiters when the star moves off the main sequence.
See de Wit et al.
Image: Carlos Villamil, Wentworth Institute of Technology and Julien de Wit, Massachusetts Institute of Technology. 2024. Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Astronomy/8_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_2.png,groundtruth,8_2.txt,MAC_Bench/Nature/Cover/Nature Astronomy/4_6.png,MAC_Bench/Nature/Cover/Nature Astronomy/4_6.png,clip,4_6.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_11.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_11.png,vitg,2_11.txt,MAC_Bench/Nature/Cover/Nature Astronomy/3_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/3_1.png,vith,3_1.txt,train
The Journal of Physical Chemistry B,2025_6,Which of the following options best describe the cover story?,"The monomeric KMP-11 phase separates to form liquid-like condensates. Different physiological factors, like temperature and pH, play vital roles in this process. Alternate charge block or (+)ve–",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2020_1.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2020_1.png,vitg,2020_1.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_6.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_49.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_49.png,vith,2023_49.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2020_3.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2020_3.png,clip,2020_3.txt,train
Trends in Microbiology,32_9,Which of the following options best describe the cover story?,"Most bacteria are encased by a mesh-like biopolymer called peptidoglycan
(PG) that protects them against turgor and from harsh environmental conditions. It
is made
up of several glycan polymers crosslinked to each other through short peptides and
forms
a net-like structure around the plasma membrane. The cover image is an artist’s impression
of the multi-layered cell envelope of the diderm model bacterium, Escherichia coli. The PG
is visible as a highly crosslinked mesh (in white) encircling the plasma membrane.
Several
classes of crosslink-specific PG endopeptidases (depicted in deep blue) that contribute
to
the dynamic remodelling of the PG sacculus during bacterial growth have been recently
discovered. In their Review in this issue, Rajguru et al. discuss the fundamental roles
of crosslink specific endopeptidases and their regulation across the bacterial genera.
Image courtesy: Harsh Kapoor",A,MAC_Bench/Cell/Cover/Trends in Microbiology/32_9.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_9.png,groundtruth,32_9.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/21_11.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_11.png,clip,21_11.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_12.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_12.png,vith,32_12.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/28_9.png,MAC_Bench/Cell/Cover/Trends in Microbiology/28_9.png,vitg,28_9.txt,val
BDJ Student,31_1,Which of the following options best describe the cover story?,"Vol 31 | Issue 3
As the new semester gets underway, BDJ Student leads on a question many of you have been asking: what does artificial intelligence mean to me as a student?
Cover illustration by Cat Sims",A,MAC_Bench/Nature/Cover/BDJ Student/31_1.png,MAC_Bench/Nature/Cover/BDJ Student/31_1.png,groundtruth,31_1.txt,MAC_Bench/Nature/Cover/BDJ Student/29_1.png,MAC_Bench/Nature/Cover/BDJ Student/29_1.png,vith,29_1.txt,MAC_Bench/Nature/Cover/BDJ Student/27_1.png,MAC_Bench/Nature/Cover/BDJ Student/27_1.png,ave_3,27_1.txt,MAC_Bench/Nature/Cover/BDJ Student/30_1.png,MAC_Bench/Nature/Cover/BDJ Student/30_1.png,clip,30_1.txt,train
Science Advances,11_6,Which of the following options best describe the cover story?,ONLINE COVER The reaction of Arabidopsis seedling skin when simultaneously exposed to a stomata-increasing small molecule and a peptide that triggers immune response. Green represents the nucleus of a cell that has the potential to become a stoma; magenta indicates the cell periphery. Herrmann and Sepuru et al. discovered that the activation of immune signaling can cross-regulate the otherwise highly specific stomatal development signaling if the availability of the shared downstream components becomes suboptimal. Images were taken with a confocal microscope. Credit: Arvid Herrmann,C,MAC_Bench/Science/Cover/Science Advances/9_30.png,MAC_Bench/Science/Cover/Science Advances/9_30.png,clip,9_30.txt,MAC_Bench/Science/Cover/Science Advances/9_44.png,MAC_Bench/Science/Cover/Science Advances/9_44.png,ave_3,9_44.txt,MAC_Bench/Science/Cover/Science Advances/11_6.png,MAC_Bench/Science/Cover/Science Advances/11_6.png,groundtruth,11_6.txt,MAC_Bench/Science/Cover/Science Advances/10_23.png,MAC_Bench/Science/Cover/Science Advances/10_23.png,vitg,10_23.txt,train
Nature Mental Health,2_12,Which of the following options best describe the cover story?,"Neuromodulating psychological traits
In this issue, Williams et al. present the results from the Stanford Hypnosis Integrated with Functional Connectivity-targeted Transcranial Stimulation (SHIFT) trial investigating imaging-guided transcranial magnetic stimulation of the left dorsolateral prefrontal cortex (L-DLPFC) to increase the ability to be hypnotized. Hypnosis has been posited as a non-pharmacological intervention for functional pain disorders. The trial demonstrated that in a sample of participants with fibromyalgia syndrome, inhibition of the L-DLPFC was associated with greater ability to be hypnotized, indicative of a promising target for noninvasive neuromodulation. The cover depicts a representation of neuromodulation of the L-DLPFC during the SHIFT paradigm.
See Williams et al.
Image: Ori Dvir. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Nature Mental Health/2_7.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_7.png,ave_3,2_7.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,clip,2_6.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,ave_2,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_12.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_12.png,groundtruth,2_12.txt,test
Joule,8_7,Which of the following options best describe the cover story?,"On the cover: This cover illustrates a pivotal application of thermoelectric (TE)
materials: waste heat recovery. High-entropy TE materials convert a substantial amount
of heat that is lost during industrial production processes into electricity. Among
various optimization strategies, the integration of high-entropy alloys with TE materials
is opening new avenues for the advancement of TE technologies. In this issue, Tang et al. provide a comprehensive overview of high-entropy TE materials, encompassing the mechanisms
underlying their high TE performance, the latest research advances, and future prospects.
Cover credit: Qiqi Tang.",A,MAC_Bench/Cell/Cover/Joule/8_7.png,MAC_Bench/Cell/Cover/Joule/8_7.png,groundtruth,8_7.txt,MAC_Bench/Cell/Cover/Joule/3_8.png,MAC_Bench/Cell/Cover/Joule/3_8.png,vith,3_8.txt,MAC_Bench/Cell/Cover/Joule/6_12.png,MAC_Bench/Cell/Cover/Joule/6_12.png,clip,6_12.txt,MAC_Bench/Cell/Cover/Joule/2_10.png,MAC_Bench/Cell/Cover/Joule/2_10.png,ave_0,2_10.txt,train
Environmental Science & Technology,2025_5,Which of the following options best describe the cover story?,This cover art showcases efforts to monitor CO2 emissions through the effective integration of multiple satellite measurements. It highlights an independent method for tracking progress in climate change mitigation.,D,MAC_Bench/ACS/Cover/Environmental Science & Technology/2015_5.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2015_5.png,clip,2015_5.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2019_10.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2019_10.png,ave_1,2019_10.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2024_1.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2024_1.png,ave_3,2024_1.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_5.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_5.png,groundtruth,2025_5.txt,train
Trends in Immunology,46_1,Which of the following options best describe the cover story?,"Experiments with particular specific pathogen-free (SPF)-inbred mouse
strains from different laboratories often yield conflicting data due to microbiota
variations
due to housing conditions. On pages 17–28, Rosshart, Bruno, and Schueler present
the option of using natural microbiota from wild mice to outcompete and replace
conventional laboratory SPF murine gut microbiota via co-housing (wildlings). They
propose that this may yield more robust, reproducible, and generalizable mouse data
in biomedical research than other models. Image credit: Ethan Tyler, NIH Division
of
Medical Arts.",D,MAC_Bench/Cell/Cover/Trends in Immunology/31_6.png,MAC_Bench/Cell/Cover/Trends in Immunology/31_6.png,clip,31_6.txt,MAC_Bench/Cell/Cover/Trends in Immunology/34_8.png,MAC_Bench/Cell/Cover/Trends in Immunology/34_8.png,vith,34_8.txt,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,vitg,39_14.txt,MAC_Bench/Cell/Cover/Trends in Immunology/46_1.png,MAC_Bench/Cell/Cover/Trends in Immunology/46_1.png,groundtruth,46_1.txt,train
Nature Reviews Psychology,3_7,Which of the following options best describe the cover story?,"In this Review, Orben et al. describe the mechanisms by which social media could amplify the developmental changes that increase adolescents’ mental health vulnerability.
Cover design: David Johnston",B,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_5.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_7.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_7.png,groundtruth,3_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_5.png,vitg,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,vith,1_7.txt,train
Nature Reviews Earth & Environment,5_1,Which of the following options best describe the cover story?,"Land-use and climate changes can reduce the resilience of river deltas to regime shifts in channel morphodynamics, estuarine turbidity and the state of coastal wetlands. This Review discusses how these regime shifts can be triggered, monitored and prevented.
Universal Images Group North America LLC / Alamy Stock Photo. Cover design: Carl Conway",D,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_1.png,vitg,2_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_9.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_9.png,clip,3_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_4.png,vith,2_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_1.png,groundtruth,5_1.txt,train
Nature Catalysis,7_1,Which of the following options best describe the cover story?,"Two catalysts in synergy
The cover highlights a one-pot process whereby a molecular photocatalyst is used for the generation of C(sp 3) radicals from substrates functionalized as N-hydroxyphthalimide esters and an iron-metalloenzyme performs azidation of such radicals in an enantioselective fashion.
See Rui et al.
Cover design: Alex Whitworth. Image: Xiongyi Huang, Johns Hopkins University, USA",A,MAC_Bench/Nature/Cover/Nature Catalysis/7_1.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_1.png,groundtruth,7_1.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_2.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Catalysis/6_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/6_3.png,ave_0,6_3.txt,MAC_Bench/Nature/Cover/Nature Catalysis/6_6.png,MAC_Bench/Nature/Cover/Nature Catalysis/6_6.png,vitg,6_6.txt,val
Bioconjugate Chemistry,2024_1,Which of the following options best describe the cover story?,Coacervate microgels (particle-like structures in light blue) were formed from IgG(Alexa488) (green) and conjugates of pullulan (light blue) with a cell membrane-permeabilizing peptide L17E (red). The interaction of the microgel leads to a dynamic structural change of the cell membrane (shown as waves) and the intracellular IgG infusion.,C,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,vitg,2013_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_5.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_1.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_2.png,vith,2016_2.txt,test
ACS Applied Polymer Materials,2024_1,Which of the following options best describe the cover story?,"The gas separation (CO2 and methane) by a polymeric membrane with xanthene units and phenyl functional groups is shown. The circle shows the application of the modified membranes in electrochemical devices (fuel cells). The image background  was created with Canvas, and the combustion cell was created with Gemini (Google).",D,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_11.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_11.png,vith,2024_11.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_6.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_6.png,vitg,2022_6.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_1.png,groundtruth,2024_1.txt,test
Nature Microbiology,9_8,Which of the following options best describe the cover story?,"Range expansion promotes cheaters
Pseudomonas aeruginosa colonies develop spatial patterns through cooperative swarming. During experimental evolution experiments, cheaters emerged, leading to the disruption of the spatial patterns and a decline in population fitness. The authors found that populations were more vulnerable to invading cheaters in a spatially extended system due to a higher level of cooperation. This collapse of cooperation during microbial range expansion is shown to be tied to its spatial dynamics: spatial structure promoted the invasion of cheaters, while in well-mixed cultures cheaters remained at low frequencies.
See Luo et al.
Credit line: Nan Luo. Cover design: Valentina Monaco",C,MAC_Bench/Nature/Cover/Nature Microbiology/6_5.png,MAC_Bench/Nature/Cover/Nature Microbiology/6_5.png,vitg,6_5.txt,MAC_Bench/Nature/Cover/Nature Microbiology/5_10.png,MAC_Bench/Nature/Cover/Nature Microbiology/5_10.png,clip,5_10.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_8.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_8.png,groundtruth,9_8.txt,MAC_Bench/Nature/Cover/Nature Microbiology/4_5.png,MAC_Bench/Nature/Cover/Nature Microbiology/4_5.png,vith,4_5.txt,train
Industrial & Engineering Chemistry Research,2024_28,Which of the following options best describe the cover story?,Tertiary water effluents from wastewater treatment plants have the potential to provide the water that will be required to power a hydrogen economy. This cover image was created with the aid of OpenAI.,C,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_11.png,vith,2022_11.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_34.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_34.png,clip,2020_34.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_28.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_28.png,groundtruth,2024_28.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_2.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_2.png,ave_2,2023_2.txt,train
ACS Catalysis,2024_21,Which of the following options best describe the cover story?,The cover depicts N-heterocyclic carbene-carbodiimide (NHC-CDI) betaines as efficient organocatalysts for β-BL polymerization to produce light poly(3-hydroxybutyrate)s with well-defined Flory–Schulz molecular weight distributions.,B,MAC_Bench/ACS/Cover/ACS Catalysis/2024_15.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_15.png,vith,2024_15.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_21.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_21.png,groundtruth,2024_21.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2020_18.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_18.png,vitg,2020_18.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2019_8.png,MAC_Bench/ACS/Cover/ACS Catalysis/2019_8.png,clip,2019_8.txt,train
ACS Medicinal Chemistry Letters,2017_4,Which of the following options best describe the cover story?,"Mixed aryl acyloxy prodrugs readily cross the cell membrane, release a charged phosphonate ligand that binds to the intracellular domain of BTN3A1, and efficiently stimulate gd T cell proliferation. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00245. View the article.",B,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_1.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_1.png,ave_1,2025_1.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_4.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_4.png,groundtruth,2017_4.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_9.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2017_9.png,ave_3,2017_9.txt,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png,clip,2025_2.txt,train
Nature Reviews Clinical Oncology,22_1,Which of the following options best describe the cover story?,"Off-the-shelf cell therapies for patients with cancer, inspired by the Review on p10.
Cover design: Carl Conway",B,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_7.png,vitg,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/22_1.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/22_1.png,groundtruth,22_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_10.png,vith,18_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/12_3.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/12_3.png,clip,12_3.txt,train
Trends in Cognitive Sciences,28_3,Which of the following options best describe the cover story?,"Math anxiety is a significant predictor of math achievement, with a negative
impact comparable to early numerical abilities and socioeconomic status. In this issue
of
Trends in Cognitive Sciences, Lau and colleagues explore the relationship between math
anxiety and math achievement, evaluating key theories such as Reduced Competency
Theory and Processing Efficiency Theory. They propose a novel avoidance theory,
suggesting that math anxiety leads to avoidance behaviors like reduced perseverance
and engagement in math, ultimately affecting math achievement. Cover art from
/Fanatic Studio/Gary Waters/Science Photo Library/Getty Images.",D,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_10.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_10.png,clip,18_10.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/27_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/27_1.png,vith,27_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/21_2.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/21_2.png,vitg,21_2.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_3.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_3.png,groundtruth,28_3.txt,val
ACS Macro Letters,2024_11,Which of the following options best describe the cover story?,Snapshot of a crystallized polyethylene chain. Force-transmitting chains are colored with red based on the principal stress. Blue chains in the amorphous region have a small principal stress.,A,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_11.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2016_12.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2016_12.png,vith,2016_12.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_3.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_3.png,clip,2023_3.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2016_10.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2016_10.png,vitg,2016_10.txt,train
Science Translational Medicine,17_786,Which of the following options best describe the cover story?,"ONLINE COVER Identity Crisis. The cover shows YFP (green), insulin (red, overlap with YFP in yellow), and a DNA counterstain (blue) in the pancreas of a 3-week-old mouse model of Wolfram syndrome (WS) lacking the Wfs1 gene. WS is an inherited disorder that results in multiple systemic symptoms including pancreatic β cell loss. Amo-Shiinoki et al. found that although WS mice were born with substantial insulin-producing β cells, as pictured, progressive dedifferentiation of β cells occurred after weaning, resulting in a mixed population of insulin- and glucagon-producing cells. The β cell lineage loss was attributable to impaired oxidative glycolysis and lowered adenosine triphosphate content, and was targetable by deletion of the endoplasmic reticulum stress–response protein Txnip. This study increases our understanding of mechanisms of β cell loss and highlights a potential therapeutic strategy for WS. Credit: Amo-Shiinoki et alMAC_Bench/Science Translational Medicine",A,MAC_Bench/Science/Cover/Science Translational Medicine/17_786.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_786.png,groundtruth,17_786.txt,MAC_Bench/Science/Cover/Science Translational Medicine/2_35.png,MAC_Bench/Science/Cover/Science Translational Medicine/2_35.png,clip,2_35.txt,MAC_Bench/Science/Cover/Science Translational Medicine/13_597.png,MAC_Bench/Science/Cover/Science Translational Medicine/13_597.png,vith,13_597.txt,MAC_Bench/Science/Cover/Science Translational Medicine/4_133.png,MAC_Bench/Science/Cover/Science Translational Medicine/4_133.png,ave_0,4_133.txt,train
ACS Sustainable Resource Management,2024_4,Which of the following options best describe the cover story?,Sustainable bio-upcycling of functional resources from ubiquitous industrial and municipal wastes into ameliorated designer bioamphiphile with tuned interfacial interactions mechanisms for trace bisphenol A removal from multifaceted municipal landfill leachate. This image was created using an Artificial Intelligence program: Microsoft Image Creator.,D,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_1.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_1.png,ave_2,2025_1.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,vitg,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_4.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_4.png,groundtruth,2024_4.txt,val
Nano Letters,2025_6,Which of the following options best describe the cover story?,"Structured light beams are scattered by a suspension of high-Z nanoparticles before hitting the detector, illustrating their production of dark-field image contrast via X-ray scattering using a 2D-beam tracking approach.",D,MAC_Bench/ACS/Cover/Nano Letters/2024_31.png,MAC_Bench/ACS/Cover/Nano Letters/2024_31.png,vith,2024_31.txt,MAC_Bench/ACS/Cover/Nano Letters/2024_9.png,MAC_Bench/ACS/Cover/Nano Letters/2024_9.png,vitg,2024_9.txt,MAC_Bench/ACS/Cover/Nano Letters/2024_42.png,MAC_Bench/ACS/Cover/Nano Letters/2024_42.png,clip,2024_42.txt,MAC_Bench/ACS/Cover/Nano Letters/2025_6.png,MAC_Bench/ACS/Cover/Nano Letters/2025_6.png,groundtruth,2025_6.txt,train
Evidence-Based Dentistry,25_1,Which of the following options best describe the cover story?,"In this issue:
This issue of Evidence Based Dentistry focusses entirely on the use of antimicrobials in dentistry. The importance of this topic cannot be overstressed given that almost 10% of antibiotic prescriptions are issued by dentists and antimicrobial resistance is an increasing threat to global public health.
Cover illustration by Gary Neill",A,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_1.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_1.png,groundtruth,25_1.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_3.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_3.png,ave_2,24_3.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_3.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_3.png,ave_3,25_3.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,clip,25_4.txt,val
iScience,27_11,Which of the following options best describe the cover story?,"On the cover: Ukiyo-e’s “ukiyo” means “impermanence of life” or “transience and difficulty
of existence” in Japanese. The image of a heart engulfed in the turbulent waves of
ukiyo-e symbolizes the purpose of this research, sounding an alarm about the emergence
of a “heart failure pandemic” rooted in the persistent infections of SARS-CoV-2 discussed
by Murata et al. We earnestly hope that the model established in this study will prove valuable for
future research on the persistent infection of SARS-CoV-2 and overcome the turbulent
waves. Image credit: Hayanon Science Manga Studio (2024).",C,MAC_Bench/Cell/Cover/iScience/26_2.png,MAC_Bench/Cell/Cover/iScience/26_2.png,ave_3,26_2.txt,MAC_Bench/Cell/Cover/iScience/23_5.png,MAC_Bench/Cell/Cover/iScience/23_5.png,clip,23_5.txt,MAC_Bench/Cell/Cover/iScience/27_11.png,MAC_Bench/Cell/Cover/iScience/27_11.png,groundtruth,27_11.txt,MAC_Bench/Cell/Cover/iScience/26_10.png,MAC_Bench/Cell/Cover/iScience/26_10.png,ave_2,26_10.txt,train
Journal of Medicinal Chemistry,2024_24,Which of the following options best describe the cover story?,"This cover art features a striking depiction of mitochondria emerging from a scientific paper adorned with illustrations of F0-ATPase and drugs. Scientists delve into groundbreaking research, seeking a cure for ischemia",A,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_24.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_24.png,groundtruth,2024_24.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_9.png,vith,2022_9.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_19.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_19.png,vitg,2021_19.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2019_3.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2019_3.png,clip,2019_3.txt,train
Science Immunology,9_91,Which of the following options best describe the cover story?,"ONLINE COVER Gut Immunocytes Travel Far and Wide. The mammalian gut is a site where dietary antigens, the microbiota, and a wide array of different cell types interact with one another to produce effects both local and systemic. Galván-Peña et al. used Kaede photoconvertible mice and single-cell genomics to track immune cell migration from the colon to the rest of the body in both homeostatic and inflammatory contexts to help delineate how the gut mediates interorgan communication. This month’s cover illustration depicts Kaede immune cells as they photoconvert from green to red fluorescence after exposure to ultraviolet light in the colon, marking them as they travel to sites far beyond the gut. Credit: A. Mastin/Science Immunology",C,MAC_Bench/Science/Cover/Science Immunology/1_4.png,MAC_Bench/Science/Cover/Science Immunology/1_4.png,clip,1_4.txt,MAC_Bench/Science/Cover/Science Immunology/5_48.png,MAC_Bench/Science/Cover/Science Immunology/5_48.png,vitg,5_48.txt,MAC_Bench/Science/Cover/Science Immunology/9_91.png,MAC_Bench/Science/Cover/Science Immunology/9_91.png,groundtruth,9_91.txt,MAC_Bench/Science/Cover/Science Immunology/5_46.png,MAC_Bench/Science/Cover/Science Immunology/5_46.png,vith,5_46.txt,val
Current Biology,34_20,Which of the following options best describe the cover story?,"On the cover: Gibbons are well known for their melodious morning song bouts. In this
issue, Ma et al. show that three adult male crested gibbon species adjust rhythm to facilitate song
coordination with adult females. This image shows an adult male cao vit gibbon (Nomascus nasutus), one of the study species with a particularly strong adjustment in rhythm. This
species is Critically Endangered, with only one population of 74 individuals, calling
for urgent conservation. Photo by Chao Zhao.",B,MAC_Bench/Cell/Cover/Current Biology/25_4.png,MAC_Bench/Cell/Cover/Current Biology/25_4.png,vitg,25_4.txt,MAC_Bench/Cell/Cover/Current Biology/34_20.png,MAC_Bench/Cell/Cover/Current Biology/34_20.png,groundtruth,34_20.txt,MAC_Bench/Cell/Cover/Current Biology/23_17.png,MAC_Bench/Cell/Cover/Current Biology/23_17.png,clip,23_17.txt,MAC_Bench/Cell/Cover/Current Biology/25_24.png,MAC_Bench/Cell/Cover/Current Biology/25_24.png,ave_2,25_24.txt,train
Journal of the American Chemical Society,2024_17,Which of the following options best describe the cover story?,"A long polypeptide chain, exceeding 700 amino acids, is propelled through a protein nanopore. Phosphorylation-specific binders, when bound to the translocating peptide, create unique signatures that enable the detection of phosphoserine sites over 250 residues apart within a single chain. [Cover by",A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_17.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_15.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_15.png,clip,2009_15.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_42.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_42.png,vitg,2011_42.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_27.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_27.png,ave_1,2009_27.txt,train
Cell Genomics,4_4,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Slimak et al. present the discovery of a late Neanderthal nicknamed Thorin found in Mediterranean
France. The Thorin population was isolated for some 50,000 years and is genetically
deeply divergent from other late Neanderthals. The recognition of distinct late Neanderthal
populations has significant implications on the Neanderthal extinction scenarios.
The cover presents a reconstruction of the jaw of Thorin, one of the most complete
Neanderthal jaws ever found. Image credit: Xavier Muth, Laure Metz, and Ludovic Slimak.",A,MAC_Bench/Cell/Cover/Cell Genomics/4_4.png,MAC_Bench/Cell/Cover/Cell Genomics/4_4.png,groundtruth,4_4.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_4.png,MAC_Bench/Cell/Cover/Cell Genomics/3_4.png,vitg,3_4.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_10.png,MAC_Bench/Cell/Cover/Cell Genomics/4_10.png,vith,4_10.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_3.png,MAC_Bench/Cell/Cover/Cell Genomics/2_3.png,clip,2_3.txt,train
Trends in Genetics,40_10,Which of the following options best describe the cover story?,"Anthropogenic climate change is leading to the rapid decline of coral
ecosystems such as those of the Great Barrier Reef (shown here). This decline has
sparked efforts to use genomics to predict and mitigate the impacts of climate change
on reefs. In this issue, Oliver Selmoni and colleagues summarize recent advances in
the
understanding of the genes and pathways controlling coral adaptation to stress and
discuss how combining genomic scans with CRISPR-Cas9 gene editing can be used to
characterize the variants under selection. Image credit: Amanda Tinoco.",B,MAC_Bench/Cell/Cover/Trends in Genetics/36_11.png,MAC_Bench/Cell/Cover/Trends in Genetics/36_11.png,clip,36_11.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_10.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_10.png,groundtruth,40_10.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_12.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_12.png,ave_2,40_12.txt,MAC_Bench/Cell/Cover/Trends in Genetics/32_10.png,MAC_Bench/Cell/Cover/Trends in Genetics/32_10.png,ave_3,32_10.txt,train
ACS Sustainable Resource Management,2024_6,Which of the following options best describe the cover story?,"Smart lignin nanoparticles effectively recover valuable resources from wastewater and, in consequence, aid to minimize anthropogenic pollution, enhance the circularity of the biorefinery economy, and support sustainable development. Designed by Ehsan Faridi and Ehsan Keshavarzi, Inmywork Studio.",D,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,ave_2,2024_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,vith,2025_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_6.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_6.png,groundtruth,2024_6.txt,train
NATURE REVIEWS NEUROSCIENCE,25_2,Which of the following options best describe the cover story?,"‘A transforming view’, inspired by the Review on p726
Cover design: Jennie Vallis",B,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_5.png,clip,15_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_2.png,groundtruth,25_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_7.png,vitg,25_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/17_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/17_4.png,vith,17_4.txt,train
Current Biology,34_12,Which of the following options best describe the cover story?,"On the cover: Seeds? Ancient artwork? No, these are the eggs of 42 species of stick
and leaf insects. In this issue, Boisseau and Woods show that this spectacular diversity in size and shape has evolved within a complex
network of causal relationships among life history, ecological, and mechanical factors.
Variation in egg size is mainly explained by variation in female resource allocation
strategy (i.e., lay many but small or few but large eggs). In contrast, variation
in egg shape mainly reflects varying levels of mechanical constraints arising from
the passage through the reproductive canals of slender, twig-mimicking species or
from derived oviposition strategies including burying the eggs in the substrate or
gluing them to the host plant instead of dropping them. Image by Romain Boisseau,
Thies Büscher, and Tom van de Kamp.",D,MAC_Bench/Cell/Cover/Current Biology/33_10.png,MAC_Bench/Cell/Cover/Current Biology/33_10.png,vith,33_10.txt,MAC_Bench/Cell/Cover/Current Biology/26_5.png,MAC_Bench/Cell/Cover/Current Biology/26_5.png,vitg,26_5.txt,MAC_Bench/Cell/Cover/Current Biology/31_16.png,MAC_Bench/Cell/Cover/Current Biology/31_16.png,clip,31_16.txt,MAC_Bench/Cell/Cover/Current Biology/34_12.png,MAC_Bench/Cell/Cover/Current Biology/34_12.png,groundtruth,34_12.txt,train
Nature Reviews Bioengineering,2_12,Which of the following options best describe the cover story?,"The motions of the heart are regulated by electrophysiological signals, which can be monitored and altered by bioelectronic devices for the diagnosis and treatment of cardiovascular diseases. In particular, soft bioelectronic devices, composed of deformable and conductive materials, can be implanted or designed as wearable devices to enable conformal contact with heart tissue or the skin for real-time and precise diagnosis and treatment. See Sung-Hyuk Sunwoo et al.
Cover image: Simon Bradbrook.",B,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_6.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_6.png,clip,2_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_12.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_12.png,groundtruth,2_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_11.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_11.png,vitg,2_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,ave_2,3_1.txt,train
Nature Cancer,5_5,Which of the following options best describe the cover story?,"A translational gene essentiality map to guide treatment in cancer
Using machine learning to build translational gene essentiality maps of patients’ tumors and normal tissue biopsies identifies oncogenes and synthetic lethalities that are predictive of drug responses and patient outcomes.
See Shi et al.
Image: Nobi Prizue / iStock / Getty Images Plus; image concept: Damian Falkowski, AbbVie BSG Creative Services. Cover design: Vanitha Selvarajan",B,MAC_Bench/Nature/Cover/Nature Cancer/1_8.png,MAC_Bench/Nature/Cover/Nature Cancer/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_5.png,MAC_Bench/Nature/Cover/Nature Cancer/5_5.png,groundtruth,5_5.txt,MAC_Bench/Nature/Cover/Nature Cancer/2_6.png,MAC_Bench/Nature/Cover/Nature Cancer/2_6.png,clip,2_6.txt,MAC_Bench/Nature/Cover/Nature Cancer/1_10.png,MAC_Bench/Nature/Cover/Nature Cancer/1_10.png,vith,1_10.txt,train
Trends in Microbiology,33_1,Which of the following options best describe the cover story?,"In this issue, Gerber-Tichet et al. provide an update on the expanding
role of the function of Toll-like receptor 4 (TLR4), a germline-encoded pattern
recognition receptor (PRR). The archetypal role TLR4 is the detection bacterial wall
components, including lipopoly- and lipo-oligo-saccharides (LPS and LOS). The cover
shows antigen-presenting cells (APCs), which are the sentinels of the immune system,
containing cell surface dimers of TLR4 dimers, one of the ten members of the TLR
family. However, TLR4 is not a one trick pony – it can also generate anti-viral innate
immune responses via TRIF-related adaptor molecule-associated signalling directly
or
indirectly (e.g., Ebola or adenovirus via an alpha-defensin bridge, respectively).
Image courtesy: Conception and design by Elina Gerber-Tichet and EJ Kremer.
BioRender® was used to generate an initial template.",D,MAC_Bench/Cell/Cover/Trends in Microbiology/33_2.png,MAC_Bench/Cell/Cover/Trends in Microbiology/33_2.png,clip,33_2.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/27_6.png,MAC_Bench/Cell/Cover/Trends in Microbiology/27_6.png,vitg,27_6.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/24_12.png,MAC_Bench/Cell/Cover/Trends in Microbiology/24_12.png,vith,24_12.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/33_1.png,MAC_Bench/Cell/Cover/Trends in Microbiology/33_1.png,groundtruth,33_1.txt,test
Cell Systems,15_10,Which of the following options best describe the cover story?,"On the cover: Materials harboring engineered bacteria and active sites are grafted
with fluorescent proteins (GFP and mCherry), visualized in yellow by merging the red
and green channels. The proteins are synthesized and autonomously released by the
encapsulated cells (visible as scattered distributed red or green dots). In this issue
of Cell Systems, Zhu et al. introduce a living grafting approach, facilitated by engineered bacteria, to functionalize
materials with modular, dynamic, and regenerated biological features, thereby broadening
their utility beyond conventional limits. Image credit: Runtao Zhu and Jiao Zhang.",B,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,vitg,1_2.txt,MAC_Bench/Cell/Cover/Cell Systems/15_10.png,MAC_Bench/Cell/Cover/Cell Systems/15_10.png,groundtruth,15_10.txt,MAC_Bench/Cell/Cover/Cell Systems/2_1.png,MAC_Bench/Cell/Cover/Cell Systems/2_1.png,clip,2_1.txt,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,vith,1_5.txt,train
Nature Neuroscience,27_7,Which of the following options best describe the cover story?,"Brain genomics in Black Americans
Racial health disparities are shaped by complex interactions among genetics and the environment . Benjamin et al. investigate differential brain gene expression and epigenetic modifications linked to ancestry variation among Black Americans, and how these relate to risks for various brain illnesses and traits.
See Benjamin et al.
Image: Tall Glass Media courtesy of the Lieber Institute for Brain Development. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Nature Neuroscience/17_7.png,MAC_Bench/Nature/Cover/Nature Neuroscience/17_7.png,vitg,17_7.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/22_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/22_2.png,vith,22_2.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/10_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/10_9.png,clip,10_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_7.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_7.png,groundtruth,27_7.txt,val
Matter,7_7,Which of the following options best describe the cover story?,"On the cover: The cover image of this issue of Matter by Feeney and Petry et al. illustrates the thermal evaporation process of a perovskite absorber in an industrial
setting. The image captures the formation of perovskite directly in its photoactive
cubic alpha phase, a result of kinetic trapping of initially formed crystallites as
they come into contact with exposed phosphonic acid anchoring groups on the surface.
In addition, the incorporation rate of formamidinium iodide (FAI) markedly increases
when the perovskite crystallizes in the alpha phase, enabling higher overall production
throughput. These insights contribute to a deeper understanding of how surface chemistry
influences the crystallization dynamics of co-evaporated perovskite precursors, thereby
advancing the field of perovskite solar cell technology.",B,MAC_Bench/Cell/Cover/Matter/2_6.png,MAC_Bench/Cell/Cover/Matter/2_6.png,clip,2_6.txt,MAC_Bench/Cell/Cover/Matter/7_7.png,MAC_Bench/Cell/Cover/Matter/7_7.png,groundtruth,7_7.txt,MAC_Bench/Cell/Cover/Matter/2_5.png,MAC_Bench/Cell/Cover/Matter/2_5.png,vitg,2_5.txt,MAC_Bench/Cell/Cover/Matter/7_1.png,MAC_Bench/Cell/Cover/Matter/7_1.png,vith,7_1.txt,train
ACS Materials Au,2024_1,Which of the following options best describe the cover story?,"RAW 264.7 monocytic cells on the experimental bone composite CP7 under osteoclastic induction. The image demonstrates a reduced number of multinucleated giant cells, suggesting an inhibitory effect of the CP7 on osteoclast formation.",D,MAC_Bench/ACS/Cover/ACS Materials Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_2.png,clip,2022_2.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_4.png,vitg,2022_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2024_1.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_1.png,groundtruth,2024_1.txt,train
Trends in Cancer,10_12,Which of the following options best describe the cover story?,"The Swiss cheese model was originally proposed to show how hazards
can pass through system defense failures or ‘holes within the cheese.’ In this issue,
Teran et al. use the Swiss cheese model to frame how tumor-promoting mechanisms
promote the development, maintenance, and progression of glioblastoma by finding
‘holes’ in multilayered homeostatic defenses. Image designed by Ashley Durand and
reprinted with permission, Cleveland Clinic Foundation.",C,MAC_Bench/Cell/Cover/Trends in Cancer/4_5.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_5.png,vith,4_5.txt,MAC_Bench/Cell/Cover/Trends in Cancer/4_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_6.png,vitg,4_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_12.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_12.png,groundtruth,10_12.txt,MAC_Bench/Cell/Cover/Trends in Cancer/1_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/1_1.png,clip,1_1.txt,train
ACS Nano,2025_6,Which of the following options best describe the cover story?,"Optical forces are utilized to enable the rapid and controllable transport of subcellular structures, such as organelles, within the natural tunneling nanotube structures between cells, which serve as biological conveyor belts.",A,MAC_Bench/ACS/Cover/ACS Nano/2025_6.png,MAC_Bench/ACS/Cover/ACS Nano/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/ACS Nano/2016_1.png,MAC_Bench/ACS/Cover/ACS Nano/2016_1.png,vitg,2016_1.txt,MAC_Bench/ACS/Cover/ACS Nano/2024_38.png,MAC_Bench/ACS/Cover/ACS Nano/2024_38.png,clip,2024_38.txt,MAC_Bench/ACS/Cover/ACS Nano/2018_2.png,MAC_Bench/ACS/Cover/ACS Nano/2018_2.png,ave_2,2018_2.txt,train
ACS ES&T Air,2024_8,Which of the following options best describe the cover story?,"Decamethylcyclopentasiloxane (D5) in personal care products vaporizes and undergoes oxidation in the atmosphere in the presence of hydroxyl radicals, resulting in the formation of oxidized compounds that contribute to aerosol formation. Such oxidation products were identified in fine particulate matter collected from the urban atmosphere of New York City. The background of this image was created by DALL·E3.",B,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_5.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_5.png,clip,2024_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,ave_1,2024_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,vith,2024_9.txt,train
Journal of Chemical Information and Modeling,2025_5,Which of the following options best describe the cover story?,"Extracting relevant structures from free energy molecular simulations can be a daunting task. The newly developed FESTA script simplifies this process, offering ease, robustness, and broad compatibility, making ""fishing"" in the free energy pond both efficient and enjoyable. View the article.",C,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2010_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2010_6.png,ave_2,2010_6.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_3.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_3.png,ave_1,2015_3.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2017_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2017_6.png,clip,2017_6.txt,train
Crystal Growth & Design,2024_10,Which of the following options best describe the cover story?,"Polycrystalline Ge is a leading candidate as a channel material for next-generation thin-film transistors; however, randomly existing grain boundaries have degraded device characteristics.",B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_8.png,clip,2017_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_10.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_7.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_7.png,vitg,2024_7.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2020_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2020_8.png,vith,2020_8.txt,train
Joule,8_10,Which of the following options best describe the cover story?,"On the cover: This graphic illustrates the advantages of luminescent solar concentrators,
particularly their flexibility and ability to alter the solar spectrum. The work by
Baikie et al. outlines their real-world potential and identifies the niches in which they may outperform
conventional solar cells. Cover credit: Tomi K. Baikie.",A,MAC_Bench/Cell/Cover/Joule/8_10.png,MAC_Bench/Cell/Cover/Joule/8_10.png,groundtruth,8_10.txt,MAC_Bench/Cell/Cover/Joule/2_10.png,MAC_Bench/Cell/Cover/Joule/2_10.png,clip,2_10.txt,MAC_Bench/Cell/Cover/Joule/3_11.png,MAC_Bench/Cell/Cover/Joule/3_11.png,ave_1,3_11.txt,MAC_Bench/Cell/Cover/Joule/2_4.png,MAC_Bench/Cell/Cover/Joule/2_4.png,vith,2_4.txt,train
Nature Electronics,7_7,Which of the following options best describe the cover story?,"Three-dimensional electronics
Our 2024 technology of the year is three-dimensional electronics.
See Editorial
Image: Kameon/iStock/Getty Images Plus. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Electronics/1_5.png,MAC_Bench/Nature/Cover/Nature Electronics/1_5.png,vitg,1_5.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_7.png,MAC_Bench/Nature/Cover/Nature Electronics/7_7.png,groundtruth,7_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/2_5.png,MAC_Bench/Nature/Cover/Nature Electronics/2_5.png,vith,2_5.txt,MAC_Bench/Nature/Cover/Nature Electronics/2_6.png,MAC_Bench/Nature/Cover/Nature Electronics/2_6.png,clip,2_6.txt,train
Nature Electronics,7_8,Which of the following options best describe the cover story?,"Microdevices find their place on conformable substrates
High-density arrays of microdevices can be site-selectively integrated on conformable substrates with the help of a velocity-controlled dip-transfer coating method that selectively deposits an adhesive precursor on the surface of the devices. The photograph on the cover shows a four-by-four array of blue micro-light-emitting diodes (microLEDs) that were assembled using the approach and are wrapped around a cylindrical rod.
See Yoon et al.
Image: Hyungsoo Yoon and Sujin Jeong, Seoul National University. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Electronics/5_7.png,MAC_Bench/Nature/Cover/Nature Electronics/5_7.png,ave_2,5_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_8.png,MAC_Bench/Nature/Cover/Nature Electronics/7_8.png,groundtruth,7_8.txt,MAC_Bench/Nature/Cover/Nature Electronics/1_3.png,MAC_Bench/Nature/Cover/Nature Electronics/1_3.png,ave_1,1_3.txt,MAC_Bench/Nature/Cover/Nature Electronics/6_1.png,MAC_Bench/Nature/Cover/Nature Electronics/6_1.png,clip,6_1.txt,train
Nature Chemistry,16_11,Which of the following options best describe the cover story?,"Links in a chain
The assembly of artificial cell-like structures into interconnected networks with collective functions can improve our understanding of artificial multicellularity and is a step towards the construction of artificial tissues. Now, Yiyang Lin, Stephen Mann, Yan Qiao and co-workers have shown that a population of coacervate micro-droplets can spontaneously assemble into chain-like networks self-sorted as alternating sequences (as shown in an artistic representation on the cover). These superstructures enable spatially localized catalysis, molecular translocation and biomolecular sorting.
See Mu et al.
Image: Yan Qiao, Institute of Chemistry, Chinese Academy of Sciences. Cover Design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/Nature Chemistry/16_11.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_11.png,groundtruth,16_11.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_5.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_5.png,clip,16_5.txt,MAC_Bench/Nature/Cover/Nature Chemistry/8_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/8_6.png,vitg,8_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/15_11.png,MAC_Bench/Nature/Cover/Nature Chemistry/15_11.png,vith,15_11.txt,val
ACS Macro Letters,2024_1,Which of the following options best describe the cover story?,"Aqueous photoiniferter polymerization of acrylonitrile, achieving high monomer conversion, faster kinetics, and controlled molecular weights, could dramatically improve polyacrylonitrile-based polymers for high-performance carbon fiber production. The AI-generated cover depicts black carbon fibers being pulled out of a beaker of shimmering saltwater, highlighting the potential application of this work.",C,MAC_Bench/ACS/Cover/ACS Macro Letters/2017_9.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2017_9.png,vitg,2017_9.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_3.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_3.png,clip,2020_3.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_1.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_1.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_1.png,ave_1,2020_1.txt,train
Nature Metabolism,6_2,Which of the following options best describe the cover story?,"Phages and food addiction
Bacteriophages in the gut microbiome are shown to regulate food addiction traits by modulating tryptophan and tyrosine metabolism in the host. The image depicts bacteriophages attacking a bacterial cell.
See Castells-Nobau et al.
Image credit: MattLphotography / Alamy Stock Photo. Cover design: Allen Beattie.",B,MAC_Bench/Nature/Cover/Nature Metabolism/2_11.png,MAC_Bench/Nature/Cover/Nature Metabolism/2_11.png,vith,2_11.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_2.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_2.png,groundtruth,6_2.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_2.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_2.png,clip,3_2.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_1.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_1.png,vitg,3_1.txt,train
Nature Reviews Materials,9_7,Which of the following options best describe the cover story?,"Hydrogels share similarities with the soft tissues of the human body, having great application prospects in tissue engineering and medical implants. Developing strong and tough hydrogels is crucial for their biomedical applications, but traditional hydrogels typically exhibit weak and brittle mechanical properties due to the inhomogeneity of their network and rubber-like elasticity, which lacks energy dissipation mechanisms. The cover art depicts a typical strategy for improving network uniformity to enhance hydrogel strength. See Li X. and Gong J. P.
Cover: David Johnston",C,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_11.png,vith,3_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_2.png,ave_1,3_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_7.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_7.png,groundtruth,9_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_6.png,clip,3_6.txt,train
Trends in Immunology,45_8,Which of the following options best describe the cover story?,"Sarcoidosis is an immunological disease characterized by the presence
of coalescing, tightly clustered, non-necrotizing granulomas. On pages 406–418, Robert
and colleagues discuss the dysregulated immune responses that may lead to granuloma
formation and maintenance; they propose the novel hypothesis that maladaptive innate
immune training may help drive sarcoidosis pathogenesis. Inspired by Mayan calendar
stones, the image alludes to different immune cells and elements present in a granuloma,
which is a key pathophysiological feature of sarcoidosis. Image credit: Bertsy Goic
drawinscience.fr.",B,MAC_Bench/Cell/Cover/Trends in Immunology/45_6.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_6.png,vith,45_6.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_8.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_8.png,groundtruth,45_8.txt,MAC_Bench/Cell/Cover/Trends in Immunology/40_2.png,MAC_Bench/Cell/Cover/Trends in Immunology/40_2.png,clip,40_2.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,vitg,36_3.txt,train
Journal of Chemical Information and Modeling,2025_2,Which of the following options best describe the cover story?,"This figure shows materials being ""scanned"" by AI, as our method applies an AI-based filter to assess prediction reliability of AI-based regression models. The depicted structures are from the COD database (CC0 license) and were processed using the Avogadro software. View the article.",D,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_6.png,ave_2,2015_6.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2016_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2016_11.png,vith,2016_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2010_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2010_6.png,clip,2010_6.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_2.png,groundtruth,2025_2.txt,train
Current Biology,34_15,Which of the following options best describe the cover story?,"On the cover: Confocal micrograph of an Arabidopsis thaliana seedling, 20 h post germination. The seed coat is still partially covering the cotyledons.
The plasma membrane is shown in magenta and the nuclei in green. In this issue, Bou Daher et al. show that xyloglucan, a cell wall polysaccharide, plays an important role in hypocotyl
emergence and root penetration in the soil during early seedling development. The
lack of xyloglucan affects the biochemical, structural, and mechanical properties
of the cell wall and induces a reduction in turgor pressure, leading to a compromised
seedling establishment. Image by Firas Bou Daher.",A,MAC_Bench/Cell/Cover/Current Biology/34_15.png,MAC_Bench/Cell/Cover/Current Biology/34_15.png,groundtruth,34_15.txt,MAC_Bench/Cell/Cover/Current Biology/34_7.png,MAC_Bench/Cell/Cover/Current Biology/34_7.png,clip,34_7.txt,MAC_Bench/Cell/Cover/Current Biology/23_6.png,MAC_Bench/Cell/Cover/Current Biology/23_6.png,ave_1,23_6.txt,MAC_Bench/Cell/Cover/Current Biology/23_12.png,MAC_Bench/Cell/Cover/Current Biology/23_12.png,vitg,23_12.txt,train
Journal of Medicinal Chemistry,2024_17,Which of the following options best describe the cover story?,Bipyridine–silver(I) compounds with phosphane co-ligands induce paraptotic cell death and emerge as interesting drug candidates for the treatment of resistant ovarian cancer (created with BioRender.com). View the article.,C,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2023_19.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2023_19.png,vith,2023_19.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,vitg,2010_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_17.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_9.png,clip,2021_9.txt,val
Neuron,113_2,Which of the following options best describe the cover story?,"On the cover: Memory has a constructive nature. In this issue of Neuron, Lei et al. investigate the underlying neural mechanisms for memory systems reconsolidation,
which explains how recall of a remote memory triggers a reconstructive memory process
in the hippocampus. During this process, a new hippocampal engram ensemble is recruited
to provide new information to the original memory. The cover image represents this
process through a “clue wall” filled with two distinct styles of clues. Abstract black-and-white
line drawings symbolize semantic memory, while vivid, detailed images represent episodic
memory. The abstract clues are concentrated near the brain’s outline, corresponding
to the prefrontal cortex, whereas the detailed images are positioned relative to the
hippocampus. These clues collectively form a “Ship of Theseus,” symbolizing memories
that can be continuously updated with new information. This metaphor highlights the
key finding of this study: memory is a reconstructive process, and we are in search
of the traces and truth of our past via integrating remote abstract memories and newly
acquired episodic information. Overall, the cover image reflects the reconstructive
nature of memory, illustrating how the process of systems reconsolidation enables
us to adapt and update our memories over time. Artwork by Ying Xu.",B,MAC_Bench/Cell/Cover/Neuron/62_3.png,MAC_Bench/Cell/Cover/Neuron/62_3.png,vitg,62_3.txt,MAC_Bench/Cell/Cover/Neuron/113_2.png,MAC_Bench/Cell/Cover/Neuron/113_2.png,groundtruth,113_2.txt,MAC_Bench/Cell/Cover/Neuron/75_3.png,MAC_Bench/Cell/Cover/Neuron/75_3.png,clip,75_3.txt,MAC_Bench/Cell/Cover/Neuron/60_5.png,MAC_Bench/Cell/Cover/Neuron/60_5.png,vith,60_5.txt,val
Nature Reviews Psychology,3_4,Which of the following options best describe the cover story?,"In this Review, Čehajić-Clancy & Halperin consolidate research from four domains in social psychology (prejudice reduction, conflict resolution, intergroup reconciliation and affective polarization) to elucidate the critical features necessary for successful intergroup interventions.
Cover design: David Johnston",D,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_9.png,ave_1,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_2.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,vith,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_4.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_4.png,groundtruth,3_4.txt,train
Cell Host&Microbe,32_5,Which of the following options best describe the cover story?,"On the cover: This special issue of Cell Host & Microbe presents a collection of articles highlighting the role of the microbiome in systemic
disease. This collection covers recent scientific advances and perspectives for future
research, including commentaries from Sartor discussing personalized treatment for
microbiome-associated diseases, Blaak and colleagues examining how gas measurements
may be used as a measurement of host health, and Gerber discussing the potential of
AI in microbiome research. Also in this issue, Boleij and colleagues consider the
role of the microbiome in cancer, Fernandez-Real and colleagues reflect on the communication
between gut microbes and the CNS, while Garza and colleagues examine the interactions
between microbiota and skin cells and Nieuwdorp and colleagues review the role of
the gut microbiota in the pathophysiology of diabetes. Further, a series of primary
research articles present new research into the systemic reach of the microbiome in
diseases and responses to therapeutic interventions. The cover image by Shen et al. draws on the Chinese theory of yin-yang harmony in which seven nutrients, including
dietary fiber, coordinate with each other to maintain the balance of the microbiota
in the human gut. A diverse diet works together to maintain health through the gut
microbiome, thereby illustrating an example of systemic coordination between the microbiome
and host behavior in health and disease.",B,MAC_Bench/Cell/Cover/Cell Host&Microbe/12_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/12_3.png,vitg,12_3.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_5.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_5.png,groundtruth,32_5.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,vith,31_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/17_2.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/17_2.png,clip,17_2.txt,test
NATURE GENETICS,56_6,Which of the following options best describe the cover story?,"Preventing pathological expansion of tandem repeats
Analysis of the FGF14-SCA27B repeat locus identifies a common 5'-flanking insertion that is present exclusively in non-pathogenic alleles and enhances repeat stability.
See Pellerin et al.
Image: Marie Stargala and Matthew Rosen. Cover design: Tulsi Voralia",C,MAC_Bench/Nature/Cover/NATURE GENETICS/49_3.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_3.png,clip,49_3.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/51_7.png,MAC_Bench/Nature/Cover/NATURE GENETICS/51_7.png,vitg,51_7.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_6.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_6.png,groundtruth,56_6.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_6.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_6.png,vith,49_6.txt,train
Trends in Biochemical Sciences,49_4,Which of the following options best describe the cover story?,"While certain levels of cellular oxidants can be beneficial for a cell and
activate various arms of the proteostasis network (symbolized by ‘life’ on the right
side of the cover), they can also be harmful, causing oxidative damage to both the
network and the cell (depicted as ‘destruction’ on the left side of the cover). On
pages
761–774, Drs. Agnes Ulfig and Ursula Jakob explore how the roles of cellular oxidants
are balanced within the proteostasis network. Cover image by Dr. Agnes Ulfig.",B,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,clip,44_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_4.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_4.png,groundtruth,49_4.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_9.png,vith,45_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_4.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_4.png,vitg,46_4.txt,train
Macromolecules,2024_20,Which of the following options best describe the cover story?,"Molecular plastics programming is reported as an effective prescriptive strategy for achieving programmable molecular-macroscopic correspondence. With each monomer envisioned as a divisible entity, constituted with building blocks (rigid, flexible, spacer coupling, linker), a set of guiding principles",D,MAC_Bench/ACS/Cover/Macromolecules/2014_22.png,MAC_Bench/ACS/Cover/Macromolecules/2014_22.png,clip,2014_22.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_16.png,MAC_Bench/ACS/Cover/Macromolecules/2010_16.png,vith,2010_16.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_3.png,MAC_Bench/ACS/Cover/Macromolecules/2010_3.png,vitg,2010_3.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_20.png,MAC_Bench/ACS/Cover/Macromolecules/2024_20.png,groundtruth,2024_20.txt,train
Nature Reviews Rheumatology,20_7,Which of the following options best describe the cover story?,"Inspired by the Review on p323.
Cover design: Steven Hall",B,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/10_11.png,vith,10_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_7.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_7.png,groundtruth,20_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,train
NATURE GENETICS,56_1,Which of the following options best describe the cover story?,"An Asian Immune Diversity Atlas
Analysis of single-cell RNA sequencing data from peripheral blood of 474 individuals of diverse Asian ancestries links cell-type-specific splicing variation with autoimmune and inflammatory disease risk.
See Tian et al.
Image: Lucie Kim, National University of Singapore. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/NATURE GENETICS/54_11.png,MAC_Bench/Nature/Cover/NATURE GENETICS/54_11.png,ave_1,54_11.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_1.png,groundtruth,56_1.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_4.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_4.png,vitg,49_4.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/53_2.png,MAC_Bench/Nature/Cover/NATURE GENETICS/53_2.png,clip,53_2.txt,test
Journal of Chemical Education,2022_9,Which of the following options best describe the cover story?,"This work presents an immersive molecular simulation tool (Manta) based on VR technology, which enables students to explore the “real” molecular structures and chemical reactions on-the-fly. View the article.",B,MAC_Bench/ACS/Cover/Journal of Chemical Education/2019_9.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2019_9.png,clip,2019_9.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2022_9.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2022_9.png,groundtruth,2022_9.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_11.png,vith,2016_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2010_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2010_5.png,vitg,2010_5.txt,train
Nature Reviews Clinical Oncology,21_1,Which of the following options best describe the cover story?,"Treating colorectal cancer with or without high microsatellite instability/mismatch repair deficiency, inspired by the Review on p839.
Cover design: Carl Conway",C,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_8.png,clip,20_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,vith,19_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_1.png,groundtruth,21_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_6.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_6.png,vitg,18_6.txt,train
Nature Climate Change,14_12,Which of the following options best describe the cover story?,"Increasing predictability of tropical circulation
The Madden–Julian Oscillation (MJO) is a mode of weekly-to-subseasonal atmospheric variability, mainly observed over the tropical Indian Ocean and tropical Pacific Ocean. The MJO strongly influences rainfall in these areas, but can also influence weather conditions in other regions of the world. Writing in this issue, Du et al. show that the MJO has become more predictable in recent decades, mainly driven by anthropogenic warming.
See Du et al. and News & Views by Jenney
Image: Nigel Prosser / Alamy Stock Photo. Cover design: Valentina Monaco",B,MAC_Bench/Nature/Cover/Nature Climate Change/12_7.png,MAC_Bench/Nature/Cover/Nature Climate Change/12_7.png,clip,12_7.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_12.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_12.png,groundtruth,14_12.txt,MAC_Bench/Nature/Cover/Nature Climate Change/9_4.png,MAC_Bench/Nature/Cover/Nature Climate Change/9_4.png,ave_3,9_4.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_5.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_5.png,ave_2,14_5.txt,val
Acta Pharmacologica Sinica,45_10,Which of the following options best describe the cover story?,"Cover Credit: PANoptosis is a new type of cell death featured with pyroptosis, apoptosis and necroptosis as a result of PANoptosome formation. The core components of PANoptosome are CASP8 and RIPK3. The picture is a fluorescence microscopic visualization of the PANoptosome formed in macrophages which can be inhibited by inhibitors of reverse electron transport. Doi: 10.1038/s41401-023-01182-8. See the article in pages 594–608",C,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_5.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_5.png,clip,41_5.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_8.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_8.png,vith,43_8.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_10.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_10.png,groundtruth,45_10.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_10.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_10.png,ave_1,44_10.txt,train
Trends in Genetics,41_2,Which of the following options best describe the cover story?,"Open reading frames with fewer than 100 codons were traditionally
omitted from genome annotation pipelines. But in recent years, it has become clear
that many of these short open reading frames encode strings of amino acids, termed
microproteins, that play important functional roles in many species. This burgeoning
field of microprotein research is the focus of this special issue of Trends in Genetics.
Image credit: Artur Plawgo/Science Photo Library/Getty Images.",A,MAC_Bench/Cell/Cover/Trends in Genetics/41_2.png,MAC_Bench/Cell/Cover/Trends in Genetics/41_2.png,groundtruth,41_2.txt,MAC_Bench/Cell/Cover/Trends in Genetics/34_9.png,MAC_Bench/Cell/Cover/Trends in Genetics/34_9.png,vitg,34_9.txt,MAC_Bench/Cell/Cover/Trends in Genetics/30_9.png,MAC_Bench/Cell/Cover/Trends in Genetics/30_9.png,vith,30_9.txt,MAC_Bench/Cell/Cover/Trends in Genetics/37_11.png,MAC_Bench/Cell/Cover/Trends in Genetics/37_11.png,clip,37_11.txt,test
Trendsin Neurosciences,47_7,Which of the following options best describe the cover story?,"Observational studies have shown that higher physical activity levels
are associated with preserved cognition as well as improved brain structural and
functional outcomes in aging individuals. Whether physical exercise in older adulthood
can causally confer benefits to cognition and promote brain health remains an
important topic of research. In this issue of Trends in Neurosciences, Nárlon Boa
Sorte Silva, Cindy Barha, Kirk Erickson, Arthur Kramer, and Teresa Liu-Ambrose
review the current evidence regarding the impact of physical exercise on cognition
and brain health outcomes in aging individuals with and without cognitive impairment.
The authors discuss underexplored neurobiological mechanisms, current knowledge
gaps, and future directions for the field. The cover image illustrates common types
of
exercise – resistance and aerobic training – known to drive neuroplastic adaptations
in the brain of aging individuals. Photo credits: J Studios/Getty Images, Pramote
Polyamate/Getty Images, and A-Digit/Getty Images. Cover design by Nárlon Boa
Sorte Silva and Teresa Liu-Ambrose.",A,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_7.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_7.png,groundtruth,47_7.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/41_3.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/41_3.png,ave_3,41_3.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/45_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/45_9.png,ave_2,45_9.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_8.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_8.png,clip,37_8.txt,test
Science Signaling,2007_399,Which of the following options best describe the cover story?,COVER This week features a  Perspective on how nicotine modulates synaptic plasticity in the prefrontal cortex. The image depicts a ball-and-stick model of nicotine.,B,MAC_Bench/Science/Cover/Science Signaling/7_355.png,MAC_Bench/Science/Cover/Science Signaling/7_355.png,vitg,7_355.txt,MAC_Bench/Science/Cover/Science Signaling/2007_399.png,MAC_Bench/Science/Cover/Science Signaling/2007_399.png,groundtruth,2007_399.txt,MAC_Bench/Science/Cover/Science Signaling/2_63.png,MAC_Bench/Science/Cover/Science Signaling/2_63.png,vith,2_63.txt,MAC_Bench/Science/Cover/Science Signaling/2_59.png,MAC_Bench/Science/Cover/Science Signaling/2_59.png,clip,2_59.txt,train
Trends in Biochemical Sciences,50_2,Which of the following options best describe the cover story?,"Heat shock activates a gene expression program to prevent irreversible
damage to macromolecules. On pages 18–32 in this issue, Desroches Altamirano
and Alberti explore how heat shock affects the protein “building blocks’’ in a cell
and
how this promotes a stress response. Heat shock inactivates certain protein blocks,
connects them into larger structures with mRNA and represses general protein
synthesis. Simultaneously, other protein blocks facilitate the synthesis of first-aid
protein blocks (HSPs) to help restore protein blocks with “compromised” structure.
Illustrated by Dr. Desroches Altamirano.",D,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,ave_2,44_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_1.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_1.png,clip,50_1.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/41_8.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/41_8.png,ave_3,41_8.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,groundtruth,50_2.txt,train
Nature Mental Health,2_10,Which of the following options best describe the cover story?,"Loneliness and social isolation
The cover of the March issue focuses on the issue of the experience of loneliness and social isolation that can occur even when one is surrounded by others. Research investigating these constructs considers the nuances of the subjective and objective dimensions — where loneliness refers to the distress that arises from feeling one does not have enough fulfilling social contact, and social isolation refers to the limited number and quality of social contacts. Notably, both are associated with poor physical and mental health. Finding ways to disrupt the feeling of loneliness and experiencing social isolation is crucial for protecting vulnerable people, such as adolescents and older adults.
Read more in our Editorial, and see Benedyk et al. on the effects of physical activity on loneliness and social isolation.
Image and cover design: Debbie Maizels",A,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,groundtruth,2_10.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_2.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_2.png,ave_3,2_2.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/1_1.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_1.png,ave_2,1_1.txt,train
Developmental Cell,59_19,Which of the following options best describe the cover story?,"On the cover: Lineage motifs, symbolized here as ink stamps, are recurring patterns
of cell fates on lineage trees. They represent developmental modules that produce
cell types in predefined ratios during processes like retina development. Furthermore,
they could facilitate adaptive variation in cell type frequencies between species
such as rat, monkey, and chicken, as shown in the pages depicting slices of retina
generated through lineage motif stamps. To learn more about how lineage motifs act
as developmental modules for control of cell type proportions, see Tran et al. Image credit: Adara Koivula.",D,MAC_Bench/Cell/Cover/Developmental Cell/28_4.png,MAC_Bench/Cell/Cover/Developmental Cell/28_4.png,vitg,28_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/58_2.png,MAC_Bench/Cell/Cover/Developmental Cell/58_2.png,clip,58_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/17_6.png,MAC_Bench/Cell/Cover/Developmental Cell/17_6.png,ave_0,17_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_19.png,MAC_Bench/Cell/Cover/Developmental Cell/59_19.png,groundtruth,59_19.txt,train
Science Signaling,2007_392,Which of the following options best describe the cover story?,"COVER This week features a Perspective on pathways through which GPCRs signal to nonreceptor tyrosine kinases. The image depicts a seven-transmembrane receptor. [Image: Christopher Bickel, AAAS]",A,MAC_Bench/Science/Cover/Science Signaling/2007_392.png,MAC_Bench/Science/Cover/Science Signaling/2007_392.png,groundtruth,2007_392.txt,MAC_Bench/Science/Cover/Science Signaling/5_225.png,MAC_Bench/Science/Cover/Science Signaling/5_225.png,vith,5_225.txt,MAC_Bench/Science/Cover/Science Signaling/8_402.png,MAC_Bench/Science/Cover/Science Signaling/8_402.png,clip,8_402.txt,MAC_Bench/Science/Cover/Science Signaling/2_61.png,MAC_Bench/Science/Cover/Science Signaling/2_61.png,vitg,2_61.txt,train
Molecular Therapy,33_2,Which of the following options best describe the cover story?,"On the cover: Chen et al. demonstrated that C-reactive protein (CRP) exacerbates renal inflammation in diabetic
kidney disease via a Smad3-NLRP3 inflammasome-dependent pathway. The image depicts
CRP binding to its receptor and triggering signaling to activate Smad3 in the cytoplasm.
Phosphorylated Smad3 translocates into the nucleus with other Smads. Following this,
Smad3 interacts with the promoter region of NLRP3, initiating NLRP3 expression. Image
credit: Haiyong Chen and Yifan Wang.",B,MAC_Bench/Cell/Cover/Molecular Therapy/26_5.png,MAC_Bench/Cell/Cover/Molecular Therapy/26_5.png,vith,26_5.txt,MAC_Bench/Cell/Cover/Molecular Therapy/33_2.png,MAC_Bench/Cell/Cover/Molecular Therapy/33_2.png,groundtruth,33_2.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_15.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_15.png,vitg,31_15.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_17.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_17.png,clip,31_17.txt,val
Nature Reviews Endocrinology,20_1,Which of the following options best describe the cover story?,"The multifaceted influence of obesity on cancer therapies, inspired by the Review on p701.
Edward Byrne",D,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/9_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/9_4.png,vitg,9_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_4.png,clip,18_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,vith,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,groundtruth,20_1.txt,train
Organic Letters,2025_3,Which of the following options best describe the cover story?,"This cover art illustrates the successful execution of visible light-driven (represented as fireworks in the cover art) asymmetric photoredox catalytic Minisci reactions of azaarenes (described as the image of the clothes on the boy in the cover art) by electron-withdrawing carbonyl radicals (described as the image of the clothes on the girl in the cover art). The use of secondary amides as substituents on the radicals is pivotal to this success, leading to the efficient synthesis of a diverse array of valuable enantioenriched amides. These amides feature azaarene-substituted tertiary carbon stereocenters at the β-position (signified by the imagery in the sky). This cover art has been designed by Tianju Shao, Yanli Yin, and Zhiyong Jiang.",C,MAC_Bench/ACS/Cover/Organic Letters/2023_49.png,MAC_Bench/ACS/Cover/Organic Letters/2023_49.png,vith,2023_49.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_5.png,MAC_Bench/ACS/Cover/Organic Letters/2025_5.png,vitg,2025_5.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_3.png,MAC_Bench/ACS/Cover/Organic Letters/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Organic Letters/2023_23.png,MAC_Bench/ACS/Cover/Organic Letters/2023_23.png,clip,2023_23.txt,train
Cell Chemical Biology,31_11,Which of the following options best describe the cover story?,"On the cover: Immune checkpoint blockade mediated by therapeutic antibodies has revolutionized
cancer treatment yet still fails many patients. Xu, Chen, Olszewski, et al. show that shortage of the building blocks (gray and red molecules) for purine synthesis
present a metabolic bottleneck (second gate) for tumor-infiltrating T cells (blue).
One-carbon supplementation in combination with immune checkpoint blockade (first gate)
can overcome these barriers to anti-cancer immunity, leading to durable tumor regressions.
Image courtesy of the authors. 3D models by LucasPresoto, jimbogies, AnshiNoWara NG+,
and ep2au are licensed under Creative Commons Attribution.",C,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_4.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_4.png,clip,19_4.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/22_4.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/22_4.png,vith,22_4.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_11.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_11.png,groundtruth,31_11.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/17_6.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/17_6.png,vitg,17_6.txt,val
ACS Agricultural Science & Technology,2024_5,Which of the following options best describe the cover story?,"The porous silicon carbide SERS microfluidic chip has high sensitivity, good stability, and outstanding enhancement factors, with a variety of application prospects. It includes the high-sensitivity detection of pesticide residues, such as carbendazim and dinotefuran, enabling the differentiation of biomolecules. In the cover image, the use of the porous silicon carbide SERS microfluidic chip is proposed for detection of pesticide residues on rapeseed surfaces, such as carbendazim and dinotefuran. The practical application scenario of the SERS microfluidic chip for rapid, efficient, high-sensitivity, and high-throughput substance differentiation detection is described.",C,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_4.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_4.png,ave_2,2024_4.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_11.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_11.png,ave_3,2024_11.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_5.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_12.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_12.png,clip,2023_12.txt,val
The Journal of Organic Chemistry,2025_2,Which of the following options best describe the cover story?,Ruthenium-catalyzed novel (Z)-3-ferrocenylideneisobenzofuran-1(3H)-one compounds were synthesized by the ortho-CH activation of benzoic acid and ferrocenyl styrene in the presence of green solvent water. Exploring the transformation of benzoic acid and styrene into crude products leads to transformation into bioactive compounds 1,C,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2022_20.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2022_20.png,vitg,2022_20.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2022_9.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2022_9.png,clip,2022_9.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_2.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2016_21.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2016_21.png,vith,2016_21.txt,train
Caner Cell,42_7,Which of the following options best describe the cover story?,"On the cover: Liu et al. reveal the evolutionary dynamics and tumor-immune interplay in acral melanoma (AM).
The cover metaphorically represents the progression from AM in situ (AMis) to invasive AM (iAM). AMis tumors (grapes near vines) are homogeneous (green),
and iAM close to them are also green, indicating monoclonal dissemination. During
vertical invasion, some grapes change in shape and color, representing increased heterogeneity.
These abnormal tumors (purple grapes) are more invasive, and APOE+CD163+ macrophages
(birds) are attracted to promote tumor invasion. Image credit: Hengkang Liu and Ruidong
Xue.",A,MAC_Bench/Cell/Cover/Caner Cell/42_7.png,MAC_Bench/Cell/Cover/Caner Cell/42_7.png,groundtruth,42_7.txt,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,clip,33_2.txt,MAC_Bench/Cell/Cover/Caner Cell/19_3.png,MAC_Bench/Cell/Cover/Caner Cell/19_3.png,vitg,19_3.txt,MAC_Bench/Cell/Cover/Caner Cell/34_1.png,MAC_Bench/Cell/Cover/Caner Cell/34_1.png,vith,34_1.txt,train
Chemistry of Materials,2025_2,Which of the following options best describe the cover story?,"Anthracene decomposes in a lanthanum-rich melt, providing a source of carbon and interstitial hydrogen for the metal flux synthesis of new compounds. This enabled the crystal growth of La3BC2H1.7, a new superconductor. Part of the image was generated using ImageFX.",A,MAC_Bench/ACS/Cover/Chemistry of Materials/2025_2.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2017_20.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2017_20.png,vitg,2017_20.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2022_12.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2022_12.png,clip,2022_12.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2023_23.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2023_23.png,vith,2023_23.txt,train
Trends in Endocrinology & Metabolism,35_11,Which of the following options best describe the cover story?,"Intermittent fasting and ketogenic diets have been gathering popularity
for their broad range of potential health benefits. In this issue, Paoli et al. (pp. 125–141)
discuss the similarities and differences in the mechanisms behind the effects of these
two interventions, whereas Ruppert and Kersten (pp. 107–124) focus on the impact of
fasting on hepatic fatty acid oxidation and ketogenesis. The cover depicts ketogenic
diet and fasting as complementary nutritional approaches. Cover credit: adapted from
lacaosa (ketogenic half) and Peter Dazeley (fasting half)/Getty Images.",A,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_11.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_11.png,groundtruth,35_11.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/24_11.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/24_11.png,vith,24_11.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/29_5.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/29_5.png,vitg,29_5.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_9.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_9.png,clip,30_9.txt,train
ACS Sustainable Resource Management,2024_9,Which of the following options best describe the cover story?,"Mixed-dimensional attapulgite clay, featuring one-dimensional rod morphology and two-dimensional lamellar morphology, are utilized for stabilizing Pickering foam and fabricating porous adsorbent materials.",A,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,vith,2024_12.txt,train
ACS Physical Chemistry Au,2024_5,Which of the following options best describe the cover story?,A molecular CO2 storage provided a platform to investigate an equation of state of a single-molecule gas as well as property-modulation of an open-[60]fullerene host by the densely packed CO2 molecule.,B,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_5.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_5.png,clip,2022_5.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_5.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_6.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_6.png,vith,2022_6.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2023_4.png,ave_1,2023_4.txt,val
Science Signaling,2007_382,Which of the following options best describe the cover story?,"COVER This week features a Perspective on cAMP signaling in PC12 cells. The image shows PC12 cells developing neurites. [Image: Matthew J. Gerdin and Lee E. Eiden, NIH]",D,MAC_Bench/Science/Cover/Science Signaling/1_43.png,MAC_Bench/Science/Cover/Science Signaling/1_43.png,clip,1_43.txt,MAC_Bench/Science/Cover/Science Signaling/2_59.png,MAC_Bench/Science/Cover/Science Signaling/2_59.png,ave_0,2_59.txt,MAC_Bench/Science/Cover/Science Signaling/2_79.png,MAC_Bench/Science/Cover/Science Signaling/2_79.png,vitg,2_79.txt,MAC_Bench/Science/Cover/Science Signaling/2007_382.png,MAC_Bench/Science/Cover/Science Signaling/2007_382.png,groundtruth,2007_382.txt,val
Cell Host&Microbe,32_3,Which of the following options best describe the cover story?,"On the cover: A devoted mother plant. It is unknown why most plant viruses are not
seed-transmissible or have very low transmission rates. In this issue of Cell Host & Microbe, Liu and Ding reveal strong immunosuppression of virus seed transmission in plants by antiviral
RNAi. The authors further show how plants program an antiviral response that is insufficient
to block virus systemic infection in the mother plant but ensures production of virus-free
offspring seedlings from the seeds of infected mother plants. This focus issue of
Cell Host & Microbe also includes a series of reviews on fungi. Here, MacAlpine and Lionakis examine
host and fungal factors involved in vulvovaginal Candidiasis susceptibility, Hill
and Round discuss fungal-host interactions in health, while Sivarajan and Klein review
fungal immunity and difficulties in fungal vaccine development. The cover image depicts
a virus-proof shield (RNAi+) built by mother plants to inhibit seed infection, thereby
preventing virus vertical transmission. Artwork by Shanshan Zhao.",D,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_9.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_9.png,ave_3,30_9.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/16_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/16_4.png,vitg,16_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/26_5.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/26_5.png,clip,26_5.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_3.png,groundtruth,32_3.txt,train
Science Translational Medicine,17_782,Which of the following options best describe the cover story?,"ONLINE COVER CAR T Kiss of Death. The cover image shows chimeric antigen receptor (CAR) T cells (green), which have been genetically modified to reduce off-tumor toxicities, forming functional immune synapses in preparation to kill colon cancer cells (magenta). Nuclei are shown in blue. Despite the success of CAR T cells in cancer treatment, a lack of unique tumor antigens often leads to on-target, off-tumor toxicities. To overcome this clinical challenge, Wang et al. improved tumor-specific targeting by genetically modifying CAR T cells to prevent their interaction with endothelial cells, reducing their ability to migrate into healthy tissues while retaining their ability to enter and eradicate tumors. Their work presents an improvement of CAR T cell therapies by minimizing their toxicities while enhancing their antitumor potential. Credit: Wang et alMAC_Bench/Science Translational Medicine",D,MAC_Bench/Science/Cover/Science Translational Medicine/5_182.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_182.png,vitg,5_182.txt,MAC_Bench/Science/Cover/Science Translational Medicine/16_728.png,MAC_Bench/Science/Cover/Science Translational Medicine/16_728.png,vith,16_728.txt,MAC_Bench/Science/Cover/Science Translational Medicine/3_66.png,MAC_Bench/Science/Cover/Science Translational Medicine/3_66.png,clip,3_66.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_782.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_782.png,groundtruth,17_782.txt,train
Macromolecules,2024_11,Which of the following options best describe the cover story?,"Diffusion dynamics of polymer chains represent a classical problem in polymer physics. Our research adopts a unique approach to comprehend the diffusion dynamics of star polymers, focusing on their shape parameter: relative shape anisotropy (κ2), which ranges from 0, encompassing all five platonic solids, to 1, representing a straight rod.",A,MAC_Bench/ACS/Cover/Macromolecules/2024_11.png,MAC_Bench/ACS/Cover/Macromolecules/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_14.png,MAC_Bench/ACS/Cover/Macromolecules/2022_14.png,ave_1,2022_14.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_11.png,MAC_Bench/ACS/Cover/Macromolecules/2014_11.png,vitg,2014_11.txt,train
Nature Microbiology,9_12,Which of the following options best describe the cover story?,"Fungal vesicles activate host immunity
This image shows confocal microscopy of macrophages with the DNA-sensing enzyme cGAS (GFP) translocating from the nucleus to the cytosol in response to the phagocytosis of extracellular vesicles isolated from the fungal pathogen Candida albicans.
See Harding et al.
Credit: Hannah Brown Harding, Massachusetts General Hospital/Harvard Medical School. Cover design: Valentina Monaco.",A,MAC_Bench/Nature/Cover/Nature Microbiology/9_12.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_12.png,groundtruth,9_12.txt,MAC_Bench/Nature/Cover/Nature Microbiology/8_4.png,MAC_Bench/Nature/Cover/Nature Microbiology/8_4.png,vitg,8_4.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_9.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_9.png,vith,9_9.txt,MAC_Bench/Nature/Cover/Nature Microbiology/1_10.png,MAC_Bench/Nature/Cover/Nature Microbiology/1_10.png,clip,1_10.txt,val
Cell Genomics,4_1,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Huguet et al. present an article focused on the interpretation of the effect size of CNVs on cognitive
ability across different gene sets related to brain and non-brain functions. The cover
image represents this article. The human genomic sequence is depicted in the background,
with blue and red parentheses indicating genomic duplications and deletions, respectively.
Circles of corresponding colors show which organ-associated gene sets affect cognitive
ability when duplicated or deleted. Therefore, the scale depicts the resulting changes
of cognitive ability for a given individual, with the left part showing a decreased
cognitive ability. Artist credit: Guillaume Huguet and Thomas Renne, authors on this
article, jointly produced the conceptual design of this cover, with Guillaume Huguet
completing the graphic illustration.",B,MAC_Bench/Cell/Cover/Cell Genomics/2_12.png,MAC_Bench/Cell/Cover/Cell Genomics/2_12.png,ave_3,2_12.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_1.png,MAC_Bench/Cell/Cover/Cell Genomics/4_1.png,groundtruth,4_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,ave_2,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_8.png,MAC_Bench/Cell/Cover/Cell Genomics/4_8.png,clip,4_8.txt,train
Nature Reviews Nephrology,20_11,Which of the following options best describe the cover story?,"Revisiting the year’s highlights, inspired by the Year-in-Review articles starting on p71.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_1.png,clip,19_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_11.png,groundtruth,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_6.png,ave_1,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_10.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_10.png,vith,17_10.txt,train
NATURE METHODS,21_9,Which of the following options best describe the cover story?,"Advanced nanopore-based peptide sequencing
Peptide sequencing by nanopore: a crow drops grapes into a pitcher with a narrow neck, representing the cleavage of a peptide into amino acids and their subsequent detection by a modified nanopore.
See Zhang et al.
Image: Li Zhao, Sichuan University. Cover design: Thomas Phillips",C,MAC_Bench/Nature/Cover/NATURE METHODS/12_9.png,MAC_Bench/Nature/Cover/NATURE METHODS/12_9.png,clip,12_9.txt,MAC_Bench/Nature/Cover/NATURE METHODS/13_12.png,MAC_Bench/Nature/Cover/NATURE METHODS/13_12.png,vith,13_12.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_9.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_9.png,groundtruth,21_9.txt,MAC_Bench/Nature/Cover/NATURE METHODS/5_6.png,MAC_Bench/Nature/Cover/NATURE METHODS/5_6.png,vitg,5_6.txt,test
Matter,7_9,Which of the following options best describe the cover story?,"On the cover: This month's cover from Pena-Francesch et al. pays homage to magnetic manipulation in comic books and superhero pop culture. New
advances in radical polymers bring new opportunities to the design and development
of metal-free organic magnetic materials, with biocompatible and squishy properties
for soft robotics and medical imaging. Image credit: Adrian Bago Gonzalez and Abdon
Pena-Francesch.",C,MAC_Bench/Cell/Cover/Matter/2_5.png,MAC_Bench/Cell/Cover/Matter/2_5.png,vitg,2_5.txt,MAC_Bench/Cell/Cover/Matter/1_2.png,MAC_Bench/Cell/Cover/Matter/1_2.png,clip,1_2.txt,MAC_Bench/Cell/Cover/Matter/7_9.png,MAC_Bench/Cell/Cover/Matter/7_9.png,groundtruth,7_9.txt,MAC_Bench/Cell/Cover/Matter/6_10.png,MAC_Bench/Cell/Cover/Matter/6_10.png,vith,6_10.txt,val
NATURE IMMUNOLOGY,25_7,Which of the following options best describe the cover story?,"Bridging the affinity gap in the germinal center
In this issue, Ray et al. preclinically validate new immunogens to elicit broadly neutralizing antibodies (bnAbs) to the membrane-proximal external region (MPER) epitope on the HIV envelope protein, and demonstrate that germinal center kinetics are driven by affinity gaps between bnAb precursors and competing B cells over time. On the cover, using a retro National Parks postcard style, the affinity gap is portrayed as a canyon, with sturdier or more treacherous bridges for B cells to ‘cross’ via affinity maturation from high-to-high or low-to-high affinity.
See Ray et al.
Image: Christina Corbaci and Lars Hangartner. Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/23_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/23_12.png,vitg,23_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/4_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/4_12.png,vith,4_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_7.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_7.png,groundtruth,25_7.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/21_3.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/21_3.png,clip,21_3.txt,val
Nature Reviews Earth & Environment,5_2,Which of the following options best describe the cover story?,"Hydropower is a renewable energy source that can contribute to growing energy demands. This Review considers the ecological consequences of hydropower plants on riverine systems and emphasizes the urgent need to mitigate ecological impacts to ensure sustainable development.
Simone Polattini / Alamy Stock Photo. Cover design: Carl Conway",A,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_2.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_2.png,groundtruth,5_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_1.png,ave_0,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_11.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_11.png,vitg,2_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/4_1.png,clip,4_1.txt,train
Trends in Biochemical Sciences,49_8,Which of the following options best describe the cover story?,"DNA breakage mechanisms at many of the most common lymphoid
chromosomal translocation fragile zones have been intriguing. The activation-induced
deaminase (AID) acts on single-stranded DNA and is a key factor in the chromosome
breakage at non-immunoglobulin loci. On pages 391–400 in this issue, Liu et al.
propose an RNA-tether model in which the binding of AID to the newly transcribed
RNA stabilizes AID to facilitate its deamination at the non-template DNA strand in
the
transcription bubble. Cover image designed by Di Liu and Lingyu Xu.",B,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/38_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/38_9.png,vith,38_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_8.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_8.png,groundtruth,49_8.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/37_8.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/37_8.png,clip,37_8.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_4.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_4.png,vitg,46_4.txt,train
Nature Reviews Physics,6_5,Which of the following options best describe the cover story?,"The cover of this issue is based on ab initio predictions of superconducting critical temperatures. See Pellegrini & Sanna
Image: Adapted from Pellegrini, C. & Sanna, A. Nat. Rev. Phys. (2024) Cover design: Susanne Harris.",D,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_5.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_5.png,vith,5_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_1.png,clip,5_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png,vitg,6_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_5.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_5.png,groundtruth,6_5.txt,train
Developmental Cell,60_2,Which of the following options best describe the cover story?,"On the cover: Artistic representation of mouse preimplantation development from zygote
to expanded blastocyst stage. During blastocyst formation, the first three embryonic
lineages are established. Unspecified cells (yellow) progressively segregate into
extraembryonic lineages (trophectoderm externally and primitive endoderm internally;
red) and inner cells at the origin of the embryo proper (pluripotent epiblast; green).
To learn more about the role of PI3K in murine epiblast and primitive endoderm specification,
see Geiselmann et al. Image credit: Adèle Micouin and Michel Cohen-Tannoudji.",D,MAC_Bench/Cell/Cover/Developmental Cell/37_6.png,MAC_Bench/Cell/Cover/Developmental Cell/37_6.png,vitg,37_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/31_3.png,MAC_Bench/Cell/Cover/Developmental Cell/31_3.png,vith,31_3.txt,MAC_Bench/Cell/Cover/Developmental Cell/57_22.png,MAC_Bench/Cell/Cover/Developmental Cell/57_22.png,clip,57_22.txt,MAC_Bench/Cell/Cover/Developmental Cell/60_2.png,MAC_Bench/Cell/Cover/Developmental Cell/60_2.png,groundtruth,60_2.txt,val
Trends in Immunology,45_10,Which of the following options best describe the cover story?,"Our special issue on ‘Neuroimmunology – I’ showcases current research
in this discipline, emphasizing the reciprocal interplay between the brain and our
nervous
systems (central or peripheral). Various cells that act as partners and guardians
of our
nervous and immune systems, e.g., microglia, are highlighted. The articles presented
here unveil key research avenues that may enable a better understanding of neurological
and neuroimmune-related disorders. The cover image reflects the metamorphosis and
tessellation technique developed by Escher; here, a neuron gradually fills in the
gaps
between immune cells, and vice versa. Image credit: Felipe A. Pinho-Ribeiro.",A,MAC_Bench/Cell/Cover/Trends in Immunology/45_10.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_10.png,groundtruth,45_10.txt,MAC_Bench/Cell/Cover/Trends in Immunology/41_5.png,MAC_Bench/Cell/Cover/Trends in Immunology/41_5.png,clip,41_5.txt,MAC_Bench/Cell/Cover/Trends in Immunology/40_7.png,MAC_Bench/Cell/Cover/Trends in Immunology/40_7.png,vitg,40_7.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,vith,36_3.txt,train
ACS Applied Bio Materials,2024_12,Which of the following options best describe the cover story?,"The antibacterial properties of nanosheet-shaped crystalline assemblies of enzymatically synthesized aminated cellulose oligomers (namely, surface-aminated synthetic nanocelluloses) and their synergy with a metal-chelating antibacterial agent, ethylenediaminetetraacetic acid, were demonstrated.",D,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_3.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_3.png,vith,2020_3.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_9.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_9.png,vitg,2022_9.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_12.png,groundtruth,2024_12.txt,train
Nature Cardiovascular Research,3_6,Which of the following options best describe the cover story?,"Brain–heart axis
Haykin et al. show that activation of the reward system in the brain modulates adrenergic input to the liver and activation of the complement system, improving cardiac vascularization and recovery after acute myocardial infarction.
See Haykin et al.
Image: Daniel Feyzullayev and Maya Reshef. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png,vith,3_8.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/4_1.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/4_1.png,vitg,4_1.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_6.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_6.png,groundtruth,3_6.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_3.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_3.png,clip,1_3.txt,train
Environmental Science & Technology,2025_2,Which of the following options best describe the cover story?,NO3RR,C,MAC_Bench/ACS/Cover/Environmental Science & Technology/2009_3.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2009_3.png,ave_1,2009_3.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2020_22.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2020_22.png,vitg,2020_22.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_2.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/1975_3.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/1975_3.png,clip,1975_3.txt,train
ACS Applied Bio Materials,2024_6,Which of the following options best describe the cover story?,"A dual-mode biosensor has been introduced in this work, which can form a sandwich structure comprising CdSeS and Au-N,S-GQD nanocomposites, in the presence of the target antigen of NoV-LP. Upon formation of the sandwich structure, fluorescence quenching and an increase in impedance were observed, depending on the concentration of target VLPs.",D,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_2.png,vitg,2022_2.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2021_12.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2021_12.png,vith,2021_12.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_11.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_11.png,clip,2019_11.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_6.png,groundtruth,2024_6.txt,train
Science Signaling,2007_409,Which of the following options best describe the cover story?,"COVER This week features a  Review concerning the possible role of asparagine deamidation as a genetically programmed molecular timer of biological processes. [Image: Christopher Bickel, AAAS]",C,MAC_Bench/Science/Cover/Science Signaling/2_63.png,MAC_Bench/Science/Cover/Science Signaling/2_63.png,ave_1,2_63.txt,MAC_Bench/Science/Cover/Science Signaling/8_378.png,MAC_Bench/Science/Cover/Science Signaling/8_378.png,clip,8_378.txt,MAC_Bench/Science/Cover/Science Signaling/2007_409.png,MAC_Bench/Science/Cover/Science Signaling/2007_409.png,groundtruth,2007_409.txt,MAC_Bench/Science/Cover/Science Signaling/1_20.png,MAC_Bench/Science/Cover/Science Signaling/1_20.png,vitg,1_20.txt,train
Nature Astronomy,8_10,Which of the following options best describe the cover story?,"Four eyes see better than one
Two thousand hours of observations split between four 25–32 m telescopes have produced a comprehensive overview of the high-energy radio emission from repeating fast radio burst source FRB 20201124A. The burst characteristics resemble those of non-repeating burst sources, suggesting a link.
See Kirsten et al.
Image: D. Futselaar/ASTRON/Chalmers/IA NCU/Astropeiler e.V/CC BY 2.0. Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Astronomy/8_10.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_10.png,groundtruth,8_10.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_4.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_4.png,clip,8_4.txt,MAC_Bench/Nature/Cover/Nature Astronomy/7_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/7_1.png,vith,7_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/6_7.png,MAC_Bench/Nature/Cover/Nature Astronomy/6_7.png,vitg,6_7.txt,test
iScience,27_8,Which of the following options best describe the cover story?,"On the cover: The parts of the cover image represent the following: (1) bluish background:
the atmospheric lack of oxygen in the universe, illustrating hypoxia; (2) two cells
compressing the brain: ischemia during asphyxia in the neonatal/perinatal brain; (3)
pink cell (left): infiltrating macrophages; (4) blue cell (right): microglia; (5)
playfully moving ribbon: change, symbolizing the causes and the complexity of the
injury and post-ischemic inflammatory cascades, but also future solutions; (6) dots
in the ribbon: the genes, transcription factors, and molecules involved in the signaling,
resulting in matrisome and metabolic dynamics in the two cell types; (7) the background
space: the extracellular matrix, a fluid/medium mediating the crosstalk between the
different actors; and (8) the pink and blue background dots: signaling molecules from
macrophages and microglia or sex differences. See Di Martino et al. Illustrator: Mattias Karlen.",C,MAC_Bench/Cell/Cover/iScience/16_1.png,MAC_Bench/Cell/Cover/iScience/16_1.png,vith,16_1.txt,MAC_Bench/Cell/Cover/iScience/24_11.png,MAC_Bench/Cell/Cover/iScience/24_11.png,vitg,24_11.txt,MAC_Bench/Cell/Cover/iScience/27_8.png,MAC_Bench/Cell/Cover/iScience/27_8.png,groundtruth,27_8.txt,MAC_Bench/Cell/Cover/iScience/24_7.png,MAC_Bench/Cell/Cover/iScience/24_7.png,clip,24_7.txt,train
Trends in Cognitive Sciences,28_10,Which of the following options best describe the cover story?,"Many cognitive neuroscientists believe that complex cognition requires
a large brain and an isocortex. Yet despite having relatively small, non-cortical
brains,
corvids and parrots exhibit cognitive abilities that are comparable to smart mammals,
including great apes. Comparing the brains of “smart” mammals and “smart” birds
can help identify which brain features are necessary for complex cognition. In this
issue of Trends in Cognitive Sciences, Onur Güntürkün and colleagues compare the
brains of mammals and birds and propose four features that may represent hard-toreplace
mechanisms supporting complex cognition: a large number of associative
pallial neurons, a prefrontal cortex (PFC)-like area, a dense dopaminergic innervation
of association areas, and dynamic neurophysiological fundaments for working memory.
Cover image from TouTouke/Getty Images.",A,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_10.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_10.png,groundtruth,28_10.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_5.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_5.png,vith,28_5.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_9.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_9.png,clip,20_9.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/26_5.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/26_5.png,vitg,26_5.txt,train
Science Advances,11_4,Which of the following options best describe the cover story?,"ONLINE COVER Simultaneous multi-color bioluminescence imaging of a cell mixture. Bioluminescence is an optical marker that does not require excitation by light. Hattori et al. developed a method to expand the bioluminescence color scheme of luciferase by establishing 20 color variants. This imaging method can be applied across various scales, from organelles to animals, and enables simple simultaneous observation of numerous biological targets and phenomena. Credit: Takeharu Nagai",B,MAC_Bench/Science/Cover/Science Advances/9_22.png,MAC_Bench/Science/Cover/Science Advances/9_22.png,vitg,9_22.txt,MAC_Bench/Science/Cover/Science Advances/11_4.png,MAC_Bench/Science/Cover/Science Advances/11_4.png,groundtruth,11_4.txt,MAC_Bench/Science/Cover/Science Advances/10_39.png,MAC_Bench/Science/Cover/Science Advances/10_39.png,vith,10_39.txt,MAC_Bench/Science/Cover/Science Advances/9_26.png,MAC_Bench/Science/Cover/Science Advances/9_26.png,clip,9_26.txt,train
Journal of Chemical Theory and Computation,2024_7,Which of the following options best describe the cover story?,Aminosterols entry pathway into a neuron-like lipid bilayer.,C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2025_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2020_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2020_1.png,ave_3,2020_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_7.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,vith,2024_17.txt,val
BDJ Student,32_1,Which of the following options best describe the cover story?,"BDJ Student - King's College London takeover
Welcome to this very special edition of BDJ Student!

In 2025, three dental schools will be taking over each of our issues. In this January edition, I'm delighted to introduce the King's College London takeover, packed full of interesting and insightful articles from one of the country's leading dental schools",B,MAC_Bench/Nature/Cover/BDJ Student/30_1.png,MAC_Bench/Nature/Cover/BDJ Student/30_1.png,clip,30_1.txt,MAC_Bench/Nature/Cover/BDJ Student/32_1.png,MAC_Bench/Nature/Cover/BDJ Student/32_1.png,groundtruth,32_1.txt,MAC_Bench/Nature/Cover/BDJ Student/29_2.png,MAC_Bench/Nature/Cover/BDJ Student/29_2.png,ave_1,29_2.txt,MAC_Bench/Nature/Cover/BDJ Student/28_3.png,MAC_Bench/Nature/Cover/BDJ Student/28_3.png,ave_3,28_3.txt,train
Developmental Cell,59_11,Which of the following options best describe the cover story?,"On the cover: This image shows a helical structure of dynamin in a post-GTP hydrolysis,
super-constricted state. This state represents a final step in dynamin-mediated fission
during endocytosis. Wrapped around a lipid tube, the assembled dynamin (dimers are
in rainbow colors) generates an inner lumen of 3.4 nm, priming the membrane for spontaneous
fission upon disassembly of the stabilizing protein coat. To learn more about how
our understanding of dynamin structure can affect membrane fission, see Jimah et al. Image credit: Jenny E. Hinshaw, John R. Jimah, and Nidhi Kundu.",B,MAC_Bench/Cell/Cover/Developmental Cell/20_2.png,MAC_Bench/Cell/Cover/Developmental Cell/20_2.png,vith,20_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_11.png,MAC_Bench/Cell/Cover/Developmental Cell/59_11.png,groundtruth,59_11.txt,MAC_Bench/Cell/Cover/Developmental Cell/48_6.png,MAC_Bench/Cell/Cover/Developmental Cell/48_6.png,clip,48_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/19_6.png,MAC_Bench/Cell/Cover/Developmental Cell/19_6.png,vitg,19_6.txt,val
Trends in Plant Science,29_2,Which of the following options best describe the cover story?,"Plants can program and reprogram their genomes to create genetic
variation and epigenetic modifications, leading to phenotypic plasticity. While
consequences of genetic changes are well understood, the basis for transgenerational
inheritance of epigenetic variation remains elusive. Shuai Cao, and Z. Jeffrey Chen
review
contributions of external (environmental) and internal (genomic) factors to initiation
and establishment of epigenetic memory during plant evolution, crop domestication,
and modern breeding. Understanding and harnessing epigenetic inheritance will help
developing effective breeding and biotechnological strategies to improve crop yield
and resilience. The cover image of a scientist pruning a hedge symbolizes the selection
process during domestication aimed at “shaping” optimal plant traits. Image credit:
Grayson Ticer.",C,MAC_Bench/Cell/Cover/Trends in Plant Science/21_7.png,MAC_Bench/Cell/Cover/Trends in Plant Science/21_7.png,vitg,21_7.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/17_2.png,MAC_Bench/Cell/Cover/Trends in Plant Science/17_2.png,clip,17_2.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_2.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_2.png,groundtruth,29_2.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/23_12.png,MAC_Bench/Cell/Cover/Trends in Plant Science/23_12.png,vith,23_12.txt,val
Journal of the American Chemical Society,2024_34,Which of the following options best describe the cover story?,Tuning acid/base electrochemistry via hydrophobicity and electric fields.  View the article.,A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_34.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_34.png,groundtruth,2024_34.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_39.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_39.png,vith,2019_39.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_47.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_47.png,vitg,2011_47.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_44.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_44.png,clip,2010_44.txt,train
Nature Reviews Chemistry,8_8,Which of the following options best describe the cover story?,"Peptide stapling provides control over conformation leading to improved stability and enhanced binding affinity. Non-symmetric stapling is more broadly applicable but introduces a requirement for high chemo-selectivity and site-selectivity. The image shows one such unsymmetrically stapled peptide binding to its target — image generated from Baeriswyl, S., Stocker, A., Reymond, J.-L., Fucosylated bicyclic peptide bp71 bound to the fucose binding lectin LecB PA-IIL from Pseudomonas aeruginosa at 1.7 Angstrom resolution (2020) https://doi.org/10.2210/pdb6y0v/pdb (PDB ID 6Y0V). The past 5 years have witnessed several significant breakthroughs in addressing these challenges and are the subject of a review by Chen et al.
Cover image: Fajie Chen; Cover design: Carl Conway",C,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/4_9.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/4_9.png,vith,4_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/3_4.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/3_4.png,vitg,3_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_8.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_8.png,groundtruth,8_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_3.png,clip,1_3.txt,train
Trends in Biochemical Sciences,49_6,Which of the following options best describe the cover story?,"Hypoxia develops when cellular or organismal demands for oxygen
exceed the oxygen supply, such as when at high altitudes. In the last few decades,
it has become apparent that sensing and responding to oxygen levels is important
for mammalian, and other multicellular organisms, physiology and pathology. In their
Opinion on pages 573–582, Dr. Ortmann and Profs. Taylor and Rocha share what
avenues of research they feel are the next pressing needs for the hypoxia community
to
address. Cover from GettyImages/Malte Mueller.",D,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/35_4.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/35_4.png,vitg,35_4.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_3.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_3.png,vith,40_3.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/38_1.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/38_1.png,clip,38_1.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_6.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_6.png,groundtruth,49_6.txt,test
The Journal of Physical Chemistry A,2025_7,Which of the following options best describe the cover story?,"Collage of artwork from recent issues of J. Phys. Chem. A. Background: Impact of Halogen Termination and Chain Length on π-Electron Conjugation and Vibrational Properties of Halogen-Terminated Polyynes (J. Phys. Chem. A 2024, 128 (14), 2703–2716. DOI:",D,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_32.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_32.png,clip,2024_32.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_46.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_46.png,vith,2024_46.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2022_44.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2022_44.png,vitg,2022_44.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_7.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_7.png,groundtruth,2025_7.txt,test
Journal of Medicinal Chemistry,2024_16,Which of the following options best describe the cover story?,"Semaglutide is a highly effective drug for type 2 diabetes and obesity. A hydrophobic fatty acid side chain in semaglutide makes the peptide sparingly soluble and its handling, multi-step synthesis, and purification difficult. Here, we replaced the fatty acid with an oligosaccharide, and the resulting glycosylated analogue is soluble, high-yielding, and biologically active. View the article.",D,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_14.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_14.png,vitg,2016_14.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_7.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_7.png,clip,2018_7.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_13.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_13.png,vith,2020_13.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_16.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_16.png,groundtruth,2024_16.txt,train
JACS Au,2024_6,Which of the following options best describe the cover story?,"Methylthioninium (MT+), the oxidized form of methylene blue (MB), catalyzes the formation of a disulfide bond in tau protein using O2, independently of its redox cycle. The presence of a disulfide bond interferes with the aggregation of tau protein. Under oxidative stress in the brain, MT+ could induce the disulfide bonds of tau proteins. This cover graphic was created by a free-to-use online AI image creator, Playground AI.",C,MAC_Bench/ACS/Cover/JACS Au/2022_7.png,MAC_Bench/ACS/Cover/JACS Au/2022_7.png,vitg,2022_7.txt,MAC_Bench/ACS/Cover/JACS Au/2021_3.png,MAC_Bench/ACS/Cover/JACS Au/2021_3.png,clip,2021_3.txt,MAC_Bench/ACS/Cover/JACS Au/2024_6.png,MAC_Bench/ACS/Cover/JACS Au/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/JACS Au/2022_12.png,MAC_Bench/ACS/Cover/JACS Au/2022_12.png,vith,2022_12.txt,train
ACS Agricultural Science & Technology,2024_8,Which of the following options best describe the cover story?,"This cover art suggests whether Surat city's soil is dominated by microplastics? The diamond symbol represents Surat's identity as the ""Diamond City"", while the thread symbolizes its thriving textile industry in Gujarat, India. The representation of garbage and plastic waste dumping reflects the daily disposal of such waste from both industrial and household sources. The lower portion of the artwork illustrates the pollution of soil by single-use plastic products within the city. The presence of the sun signifies the breakdown of large plastics into smaller microplastics, driven by UV degradation and other environmental factors. This transformation is further depicted through a magnifying lens, showcasing various shapes, such as fragments, fibers, films, and spheres, highlighting the biological and physical degradation of plastics.",C,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_1.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_1.png,clip,2022_1.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_2.png,ave_3,2023_2.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_8.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_3.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_3.png,vith,2024_3.txt,train
Nature Water,2_1,Which of the following options best describe the cover story?,"A socioeconomic view of antimicrobials
Monitoring the use of antimicrobial agents is a necessary step to find solutions to the emergence of antimicrobial resistance. One aspect that is rarely investigated is the connection of antimicrobial concentration with the socioeconomic status of the population. The image on the cover shows a heatmap illustrating per capita excreted loads of 56 detected antimicrobials and their transformation products, as reflected in wastewater influent from 50 wastewater treatment plants (WWTPs) across Australia. Each WWTP is characterized by varying population sizes, geographical remoteness, and socioeconomic statuses. The notable variation in antimicrobial excreted loads indicates diverse antimicrobial use behaviours among different populations in Australia.
See Li et al.
Image: Jinglong Li, The University of Queensland. Cover design: Laoise Mac Gabhann",D,MAC_Bench/Nature/Cover/Nature Water/3_1.png,MAC_Bench/Nature/Cover/Nature Water/3_1.png,ave_3,3_1.txt,MAC_Bench/Nature/Cover/Nature Water/1_8.png,MAC_Bench/Nature/Cover/Nature Water/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Water/2_2.png,MAC_Bench/Nature/Cover/Nature Water/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,groundtruth,2_1.txt,train
ACS Sustainable Resource Management,2025_2,Which of the following options best describe the cover story?,Thermoprocessing glycerol/water-plasticized biopolymers with bio-waste using industrial methods to replace industrial processing of plastics with renewable materials.,C,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_1.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,ave_2,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,ave_3,2024_10.txt,val
Cell Reports Physical Science,6_1,Which of the following options best describe the cover story?,"On the cover: A visual celebration of Cell Reports Physical Science’s fifth anniversary, featuring all of our covers from Volume 1, Issue 1 to December
2024’s Volume 5, Issue 12. We’d like to thank Cell Press’s own Philip Krzeminski for
his help in creating this beautiful cover.",D,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_2.png,clip,5_2.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_2.png,vitg,6_2.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_6.png,ave_0,4_6.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_1.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_1.png,groundtruth,6_1.txt,train
Journal of the American Chemical Society,2024_26,Which of the following options best describe the cover story?,"A dataset of high-quality band gaps for perovskite materials is first generated through an advanced electronic structure method and then used to develop a simple but accurate band-gap model through artificial intelligence. This enables a search across large databases, leading to the identification of promising halide perovskites for photovoltaic applications.",C,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_48.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_48.png,clip,2017_48.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_47.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_47.png,vith,2011_47.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_26.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_26.png,groundtruth,2024_26.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_47.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_47.png,vitg,2016_47.txt,train
Trends in Parasitology,40_6,Which of the following options best describe the cover story?,"Microscopy image analysis is critical in parasitology research because
it allows researchers to analyze parasite shape, function, and life cycles. Traditional
artificial intelligence (AI) methods often have limitations due to their black-box
nature
and lack of integration with human expert knowledge, which impedes their explainability
and performance. In this issue of Trends in Parasitology, Feng et al. review the recent
advancements in knowledge-integrated AI models for the analysis of parasite microscopy
images. By incorporating expert knowledge from parasitologists into AI, the resulting
knowledge-integrated models can offer both high accuracy and explainability. This
synergy is especially important in parasitology, where the correct identification
of parasites
is crucial for the treatment and control of the disease. The cover image represents
the
partnership between AI and parasitologists, demonstrating how this paradigm leads
to
better diagnostics and research in parasitology. Image credit: Sen Li.",C,MAC_Bench/Cell/Cover/Trends in Parasitology/37_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/37_2.png,vith,37_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/39_10.png,MAC_Bench/Cell/Cover/Trends in Parasitology/39_10.png,clip,39_10.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_6.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_6.png,groundtruth,40_6.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/38_11.png,MAC_Bench/Cell/Cover/Trends in Parasitology/38_11.png,vitg,38_11.txt,train
Caner Cell,42_1,Which of the following options best describe the cover story?,"On the cover: Yang et al. reveal a mechanism of immune evasion of tumor-initiating cells (TICs) and suggest
the strategy of combining CD155 blockade with anti-PD-1/PD-L1 therapy. The cover image
shows a cuckoo chick in a host bird’s nest, symbolizing CD49f+ TICs within the tumor microenvironment. The host bird represents neutrophils, attracted
to the cuckoo through its mimicry of the host’s calls, similar to how TICs release
CXCL2 to recruit neutrophils. The host then invests resources to feed the cuckoo,
paralleling neutrophils secreting CCL4 to support TIC survival. As the cuckoo matures,
its feathers (representing CD155) help it blend in and evade predators like the snake,
which symbolizes CD8+ T cells.",A,MAC_Bench/Cell/Cover/Caner Cell/42_1.png,MAC_Bench/Cell/Cover/Caner Cell/42_1.png,groundtruth,42_1.txt,MAC_Bench/Cell/Cover/Caner Cell/29_2.png,MAC_Bench/Cell/Cover/Caner Cell/29_2.png,vitg,29_2.txt,MAC_Bench/Cell/Cover/Caner Cell/42_2.png,MAC_Bench/Cell/Cover/Caner Cell/42_2.png,vith,42_2.txt,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,clip,33_2.txt,train
Journal of the American Chemical Society,2024_7,Which of the following options best describe the cover story?,A light-emitting diode based on an organic polymer crystal generates circular-polarized emission from topological photonic valleys. It can be used for virtual reality and 3D displays.,B,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_11.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_11.png,vith,2016_11.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_7.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_48.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_48.png,clip,2017_48.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_24.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_24.png,vitg,2018_24.txt,test
NATURE REVIEWS NEUROSCIENCE,25_11,Which of the following options best describe the cover story?,"‘Synaptic engineering’, inspired by the Perspective on p131.
Cover design: Jennie Vallis",C,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_3.png,clip,22_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_8.png,vitg,24_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_11.png,groundtruth,25_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,vith,25_3.txt,train
Molecular Pharmaceutics,2024_5,Which of the following options best describe the cover story?,"Highlighting the strong tradition of research excellence in pharmaceutics from the island of Ireland, the American Chemical Society journal Molecular Pharmaceutics is pleased to present a Virtual Special Issue titled ""Advances in Small and Large Molecule Pharmaceutics Research across Ireland.""  Within the VSI, the Guest Editors have collected a wide range of articles that spotlight the breadth of research in the region.  An accompanying editorial  by the Guest Editors provides context and commentary to accompany the collection.",B,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_1.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_1.png,vitg,2024_1.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_5.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_4.png,clip,2022_4.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_5.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_5.png,vith,2022_5.txt,train
Nature Cities,1_11,Which of the following options best describe the cover story?,"Green space use and COVID
The COVID-19 pandemic redefined the use of urban space worldwide. This systematic review considers how urban green space use, such as in this park in Singapore, changed in 60 countries and found disturbing disparities.
See Kleinschroth et al.
Image: Fritz Kleinschroth, ETH Zürich. Cover Design: Lauren Heslop.",A,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,groundtruth,1_11.txt,MAC_Bench/Nature/Cover/Nature Cities/2_1.png,MAC_Bench/Nature/Cover/Nature Cities/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,vitg,1_2.txt,MAC_Bench/Nature/Cover/Nature Cities/1_10.png,MAC_Bench/Nature/Cover/Nature Cities/1_10.png,ave_3,1_10.txt,train
The Journal of Physical Chemistry A,2025_1,Which of the following options best describe the cover story?,Electron transfer through a single molecule: electron tunneling through a molecule on the edge of decoupling layers on metal surfaces is subject to coulomb blockage due to the interaction with the electrons in the molecule.,A,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_1.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_44.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_44.png,vith,2024_44.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2010_40.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2010_40.png,clip,2010_40.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_30.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_30.png,vitg,2024_30.txt,train
Matter,7_8,Which of the following options best describe the cover story?,"On the cover: This month's cover pays homage to the art nouveau style of vintage alcohol
ads during the early 20th century, specifically the famous “Woman Tips Giant Martini
Glass” ad for Balsam Aperitif by F.X. de Beukelaer distillers, highlighting the hydrophobic
drops of the beverage. In this issue, Jiang and colleagues demonstrate that the contact angles of alcoholic beverages follow a step-like behavior
at critical points, which also correlates to the alcohol content and temperature preference
of popular beverages such as beer, wine, whisky, or Chinese baijiu.",B,MAC_Bench/Cell/Cover/Matter/3_3.png,MAC_Bench/Cell/Cover/Matter/3_3.png,vitg,3_3.txt,MAC_Bench/Cell/Cover/Matter/7_8.png,MAC_Bench/Cell/Cover/Matter/7_8.png,groundtruth,7_8.txt,MAC_Bench/Cell/Cover/Matter/7_4.png,MAC_Bench/Cell/Cover/Matter/7_4.png,clip,7_4.txt,MAC_Bench/Cell/Cover/Matter/4_3.png,MAC_Bench/Cell/Cover/Matter/4_3.png,vith,4_3.txt,val
Organometallics,2025_2,Which of the following options best describe the cover story?,"This cover art is a concise and retro-artistic representation of our research, a synthesis using high-pressure nitrogen. In this work, we have succeeded for the first time in analyzing the single crystal structure of a dinitrogen complex, [Cr(PCy3)2(CO)3(N2)], which has been known for a long time. We also revealed the very interesting property of disorder of the nitrogen and carbonyl ligands in the crystal by polarized infrared spectroscopy. The cover art was designed by Shinya Takaishi and created by using Open AI DALL-E 3.",D,MAC_Bench/ACS/Cover/Organometallics/2022_19.png,MAC_Bench/ACS/Cover/Organometallics/2022_19.png,vith,2022_19.txt,MAC_Bench/ACS/Cover/Organometallics/2024_15.png,MAC_Bench/ACS/Cover/Organometallics/2024_15.png,vitg,2024_15.txt,MAC_Bench/ACS/Cover/Organometallics/2024_3.png,MAC_Bench/ACS/Cover/Organometallics/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/Organometallics/2025_2.png,MAC_Bench/ACS/Cover/Organometallics/2025_2.png,groundtruth,2025_2.txt,train
Nature Food,5_7,Which of the following options best describe the cover story?,"Greenhouse cultivation boom
Greenhouse cultivation has been expanding rapidly in recent years. Commercial nanosatellite imagery and artificial intelligence techniques reveal 1.3 million hectares of greenhouse infrastructures in 2019 — a much larger number than previously estimated. This includes large-scale (61%) and small-scale (39%) greenhouse infrastructures. A close examination of the temporal development of the 65 largest greenhouse clusters (>1,500 ha) suggests an upsurge in greenhouse cultivation in the Global South since the 2000s, including a dramatic increase in China (which accounts for 60% of the global greenhouse coverage). Major greenhouse clusters in the Global North were predominantly established in the 1970s and 1980s, while clusters in the Global South emerged around the 1990s and 2000s — but have grown more rapidly since.
See Tong et al.
Image: Justin Paget/DigitalVision/Getty. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Food/4_9.png,MAC_Bench/Nature/Cover/Nature Food/4_9.png,ave_3,4_9.txt,MAC_Bench/Nature/Cover/Nature Food/2_2.png,MAC_Bench/Nature/Cover/Nature Food/2_2.png,ave_2,2_2.txt,MAC_Bench/Nature/Cover/Nature Food/2_7.png,MAC_Bench/Nature/Cover/Nature Food/2_7.png,clip,2_7.txt,MAC_Bench/Nature/Cover/Nature Food/5_7.png,MAC_Bench/Nature/Cover/Nature Food/5_7.png,groundtruth,5_7.txt,val
NATURE REVIEWS IMMUNOLOGY,24_9,Which of the following options best describe the cover story?,"Geographical variation in vaccine responses, inspired by the Review on p250.
Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/21_11.png,vith,21_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_3.png,clip,23_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_9.png,vitg,23_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_9.png,groundtruth,24_9.txt,train
NATURE REVIEWS GENETICS,26_1,Which of the following options best describe the cover story?,"Inspired by the Review on p7.
Cover design: Patrick Morgan",C,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_9.png,clip,15_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/26_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/26_1.png,groundtruth,26_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,test
Science Robotics,9_92,Which of the following options best describe the cover story?,"ONLINE COVER Robot Visual Trajectory Following. A bioinspired vision-based approach can enable small autonomous drones to follow routes over long distances. Van Dijk et al. developed a strategy for robot trajectory following that is inspired by desert ants to enable small drones to navigate without the need for high computational demands. The strategy combines odometry with highly compressed visual snapshots to record outbound flights with minimal memory consumption. Visual homing was then used on inbound flights to minimize the potential of drifting off course in autonomous drone navigation. This month’s cover shows a lightweight drone capable of visual route following to navigate in a forested environment. Credit: TU Delft, photo by Studio Oostrum",D,MAC_Bench/Science/Cover/Science Robotics/8_82.png,MAC_Bench/Science/Cover/Science Robotics/8_82.png,clip,8_82.txt,MAC_Bench/Science/Cover/Science Robotics/5_41.png,MAC_Bench/Science/Cover/Science Robotics/5_41.png,vith,5_41.txt,MAC_Bench/Science/Cover/Science Robotics/6_55.png,MAC_Bench/Science/Cover/Science Robotics/6_55.png,vitg,6_55.txt,MAC_Bench/Science/Cover/Science Robotics/9_92.png,MAC_Bench/Science/Cover/Science Robotics/9_92.png,groundtruth,9_92.txt,val
Industrial & Engineering Chemistry Research,2024_18,Which of the following options best describe the cover story?,"A novel microwave catalyst exhibits outstanding CO2 oxidative propane dehydrogenation (CO2-ODHP) performance by microwave catalysis at low temperatures, and the doping of Y greatly improved stability and regeneration performance for ZnO. This work cleverly utilizes microwave characteristics to solve the contradiction between conversion and selectivity in propane dehydrogenation.",A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_18.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_18.png,groundtruth,2024_18.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,vith,2024_36.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_19.png,clip,2018_19.txt,train
ACS Nano,2025_3,Which of the following options best describe the cover story?,"sequential-logic-in-memory (S-LiM) concept using a single van der Waals ferroelectric field-effect transistor (vdW FeFET) capable of performing sequential logic operations in two non-volatile states. This compact and energy-efficient design offers substantial advantages for edge computing, positioning the vdW FeFET as a promising candidate for next-generation edge computing devices that require high performance and versatility in resource-constrained environments. View the article.",D,MAC_Bench/ACS/Cover/ACS Nano/2024_19.png,MAC_Bench/ACS/Cover/ACS Nano/2024_19.png,clip,2024_19.txt,MAC_Bench/ACS/Cover/ACS Nano/2017_6.png,MAC_Bench/ACS/Cover/ACS Nano/2017_6.png,ave_2,2017_6.txt,MAC_Bench/ACS/Cover/ACS Nano/2021_8.png,MAC_Bench/ACS/Cover/ACS Nano/2021_8.png,ave_1,2021_8.txt,MAC_Bench/ACS/Cover/ACS Nano/2025_3.png,MAC_Bench/ACS/Cover/ACS Nano/2025_3.png,groundtruth,2025_3.txt,train
The Journal of Physical Chemistry Letters,2025_4,Which of the following options best describe the cover story?,"The cover art is a graphical illustration of dark-field detection for enhancement in circular dichroism (CD) spectroscopy of a thin film of uniaxially distributed naproxen microcrystals. Differentially circularly polarized light, represented by the top left arrows rotating opposite directions, passes through a crystalline thin film. This enhancement is represented by the CD spectra on the bottom center. The incoherent, scattered contributions to the transmitted beam leading to the enhancement are isolated by dark-field detection, in which the unscattered light is preferentially rejected by a spatial filter, depicted in the bottom right. Unlike the isotropic CD response, which arises primarily from magnetic dipole contributions, the incoherent CD produces a chiral response that is fully electric-dipole-allowed, much larger than the corresponding isotropic chiral response, and non-reciprocal (inverts upon sample reorientation). The non-resonant (linear birefringence) and resonant (linear dichroism) transition moments dominating the electric-dipole-allowed chiral response of the test system, (S)-naproxen, are pictured in the bottom left of the image.",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2023_46.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2023_46.png,vitg,2023_46.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_4.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2017_7.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2017_7.png,clip,2017_7.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2017_6.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2017_6.png,vith,2017_6.txt,train
Nature Human Behaviour,8_2,Which of the following options best describe the cover story?,"Menstruation matters
Menstruation is part of human life but is stigmatized and rarely discussed openly, and this has far-reaching implications for health, poverty and gender inequity. It is time for this to change. This Focus throws light on some of the most important ways that menstruation shapes society, health and individual lives. With it, we hope to spark more open conversations about menstruation.
See Focus
Image: andrew payne/Alamy Stock Photo. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Human Behaviour/2_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/2_4.png,clip,2_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_12.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_12.png,vitg,7_12.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/1_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/1_2.png,ave_2,1_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_2.png,groundtruth,8_2.txt,val
Molecular Plant,17_6,Which of the following options best describe the cover story?,"On the cover: The cover image is inspired by the ancient Chinese myth about the first human beings,
Fuxi (伏羲) and Nuwa (女娲), who were originally brother and sister born from Hua Xu (华胥).
They married after a devastating flood and created humanity. The sexuality differentiation
and reproduction in maize shares similarity to this story. Maize florets from tassel
and ear both bear a full set of sexual organs initially, like siblings, and undergo
selective elimination of pistil and stamen, respectively, leading to unisexual male
and female flowers. In the process of sexual differentiation, JA, BR and ROS signals
together with NAC genes inhibit the growth of pistils in tassel florets, while GA
signal, SK1 and MADS-box genes promote the growth of pistils in ear florets. In addition,
GA signal also inhibits the growth of stamens in ear florets. At the mature stage,
tassel inflorescence at the top produces pollens that scatter onto the ear filaments
at the waist to complete fertilization and production. In this cover illustration,
the floret before sex differentiation (middle) represents Hua Xu, while tassel (upper)
and ear (lower) florets formed after sex differentiation represent Fuxi and Nuwa,
respectively. The developmental process from bisexual to unisexual florets of tassel
and ear is regulated by different factors that are scattered by Fuxi and Nuwa, respectively.
Image by Yonghao Sun, Lu Kang, Liang Dong and Fang Yang.",C,MAC_Bench/Cell/Cover/Molecular Plant/15_6.png,MAC_Bench/Cell/Cover/Molecular Plant/15_6.png,clip,15_6.txt,MAC_Bench/Cell/Cover/Molecular Plant/12_10.png,MAC_Bench/Cell/Cover/Molecular Plant/12_10.png,ave_1,12_10.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_6.png,MAC_Bench/Cell/Cover/Molecular Plant/17_6.png,groundtruth,17_6.txt,MAC_Bench/Cell/Cover/Molecular Plant/11_7.png,MAC_Bench/Cell/Cover/Molecular Plant/11_7.png,ave_2,11_7.txt,train
Developmental Cell,59_21,Which of the following options best describe the cover story?,"On the cover: Artistic representation of a cross-section of the human genital ridge
at 6 weeks post-fertilization, including the gonad and the mesonephros. The gonad
is populated by NR2F2+ stromal cells (highlighted in magenta), while the mesonephros
features NR2F2+ and GATA2+ stromal cells (highlighted in green). During development,
the mesonephros functions initially as a kidney, later transforming into a sex-specific
reproductive tract. To learn more about human fetal sex-specific gonadogenesis and
the development of the reproductive tract, see Taelman et al. Image credit: Sylwia Czukiewska.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_21.png,MAC_Bench/Cell/Cover/Developmental Cell/59_21.png,groundtruth,59_21.txt,MAC_Bench/Cell/Cover/Developmental Cell/17_6.png,MAC_Bench/Cell/Cover/Developmental Cell/17_6.png,clip,17_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_12.png,MAC_Bench/Cell/Cover/Developmental Cell/59_12.png,vitg,59_12.txt,MAC_Bench/Cell/Cover/Developmental Cell/22_1.png,MAC_Bench/Cell/Cover/Developmental Cell/22_1.png,vith,22_1.txt,test
Trends in Cognitive Sciences,28_11,Which of the following options best describe the cover story?,"Psychological traits, including emotions, values, social behaviors, and
personality, exhibit variability across historical periods. These traits are reflected
in
the cultural artifacts of different periods. However, until recently, psychologists
have
largely lacked the tools needed to systemically analyze these ‘cultural fossils’.
In this
issue of Trends in Cognitive Sciences, Nicholas Baumard and colleagues review how
recent computational advances are being used to systematically explore variability
in
cultural fossils, including the literature, paintings, and music of different periods,
and
what this variability may tell us about the values and preferences of different cultures.
For example, the authors examine how variations in depictions of children in paintings
may illuminate parental attitudes throughout different historical periods. Cover image:
Manuel Osorio Manrique de Zuñiga (1784–1792) by Goya.",C,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_9.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_9.png,clip,17_9.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/22_11.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/22_11.png,ave_2,22_11.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_11.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_11.png,groundtruth,28_11.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_12.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_12.png,vitg,20_12.txt,test
Trends in Genetics,40_6,Which of the following options best describe the cover story?,"Wild grape (Vitis) species (e.g., Vitis berlandieri, photo) thrive in diverse climates and soils across the Northern Hemisphere. Wild
Vitis spp. have proven crucial
for their resilience to environmental and biological challenges faced by grape production
worldwide. Incorporating adaptive traits from Vitis spp. will be essential for viticulture's
future survival and adaptability. Cantu et al. describe how phased diploid genomes and
graph-based pangenomes of wild Vitis spp. have led to breakthroughs in understanding
grape evolution and the genetic bases of adaptive traits. Photo by Dario Cantù.",B,MAC_Bench/Cell/Cover/Trends in Genetics/29_2.png,MAC_Bench/Cell/Cover/Trends in Genetics/29_2.png,vith,29_2.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_6.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_6.png,groundtruth,40_6.txt,MAC_Bench/Cell/Cover/Trends in Genetics/30_11.png,MAC_Bench/Cell/Cover/Trends in Genetics/30_11.png,vitg,30_11.txt,MAC_Bench/Cell/Cover/Trends in Genetics/33_6.png,MAC_Bench/Cell/Cover/Trends in Genetics/33_6.png,clip,33_6.txt,test
Nature Protocols,19_9,Which of the following options best describe the cover story?,"Tumor cell captured via magnetic beads functionalized with tetrahedral DNA frameworks
Scanning electron micrograph of streptavidin-labeled magnetic beads (green) bound to biotin-labeled tetrahedral DNA frameworks anchored with aptamers to a HepG2 cell (pink). See Chen, Y. et al.
Image: [ Yirong Chen, Dekai Ye and Min Li, Shanghai Jiao Tong University] Cover design: S. Whitham",C,MAC_Bench/Nature/Cover/Nature Protocols/14_4.png,MAC_Bench/Nature/Cover/Nature Protocols/14_4.png,clip,14_4.txt,MAC_Bench/Nature/Cover/Nature Protocols/18_1.png,MAC_Bench/Nature/Cover/Nature Protocols/18_1.png,vitg,18_1.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,groundtruth,19_9.txt,MAC_Bench/Nature/Cover/Nature Protocols/16_11.png,MAC_Bench/Nature/Cover/Nature Protocols/16_11.png,vith,16_11.txt,train
ACS Materials Letters,2024_7,Which of the following options best describe the cover story?,"A data-driven biomimetic approach is used to mimic the functionally graded structure of the Coscinodiscus species diatom for the design of architected honeycombs with tunable mechanical properties. The proposed approach leads to a novel design, which features a performance increase of 250% with respect to conventional honeycombs.",A,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_7.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2020_12.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2020_12.png,clip,2020_12.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_5.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_5.png,vitg,2019_5.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_1.png,vith,2024_1.txt,train
Chemical & Biomedical ImagingOpen Access,2024_1,Which of the following options best describe the cover story?,"A universal, rapid and large-scale synthesis strategy for chiral fluorescent",C,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_4.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_4.png,ave_2,2023_4.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_3.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_3.png,ave_1,2023_3.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,clip,2024_11.txt,val
Developmental Cell,59_15,Which of the following options best describe the cover story?,"On the cover: The image shows examples of 3D epiblast stem cells (EpiSCs), which model
the early gastrulating mouse epiblast, arranged artistically. The general structure
of the 3D EpiSCs is depicted by F-actin staining (sepia) and a nuclear DAPI staining
(cyan). Cells that express the primitive streak marker Brachyury are shown in magenta.
To learn more about how these cells emerge in homogenous culture conditions and provide
insight into early mouse development, see Sato et al. Image credit: Marta Shahbazi.",B,MAC_Bench/Cell/Cover/Developmental Cell/28_1.png,MAC_Bench/Cell/Cover/Developmental Cell/28_1.png,vith,28_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_15.png,MAC_Bench/Cell/Cover/Developmental Cell/59_15.png,groundtruth,59_15.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,vitg,59_20.txt,MAC_Bench/Cell/Cover/Developmental Cell/57_22.png,MAC_Bench/Cell/Cover/Developmental Cell/57_22.png,clip,57_22.txt,val
Industrial & Engineering Chemistry Research,2024_46,Which of the following options best describe the cover story?,Aqueous two-phase systems,C,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_5.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_5.png,vith,2021_5.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_27.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_27.png,clip,2023_27.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_46.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_46.png,groundtruth,2024_46.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,val
Journal of Medicinal Chemistry,2024_20,Which of the following options best describe the cover story?,"The cover art showcases the intricate molecular interaction where DD-2 (PROTAC) facilitates a ternary complex formation with E3 ubiquitin ligase (UBR) and the polo-box domain (PBD) of the PLK1 protein. This binding event initiates a cascade of ubiquitination leading to the targeted degradation of PLK1, a key regulator in cell cycle progression, thereby showcasing the potential of DD-2 in triggering antitumor activity through a ubiquitin–proteasome pathway. View the article.",B,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_10.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_10.png,vitg,2016_10.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_20.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_20.png,groundtruth,2024_20.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_6.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_6.png,clip,2018_6.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2011_3.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2011_3.png,ave_1,2011_3.txt,train
Trends in Cell Biology,34_6,Which of the following options best describe the cover story?,"Neuronal ferroptosis is central to several neurological diseases.
On pages 535–546 in this issue, Jacquemyn et al. discuss how alterations in iron
and lipid metabolism affect neuronal ferroptosis in health and disease. Fundamental
features of neurons that make them vulnerable to ferroptosis and the unique strategies
neurons use to protect themselves from it are highlighted. Finally, the reciprocal
roles
of neuronal iron, lipids, and pathogenic proteins in ferroptosis in neurodegenerative
disease are discussed. Cover design by Dr. Julie Jacquemyn.",B,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_7.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_7.png,vith,23_7.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_6.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_6.png,groundtruth,34_6.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_4.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_4.png,vitg,23_4.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/21_8.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/21_8.png,clip,21_8.txt,train
Chemical Research in Toxicology,2024_8,Which of the following options best describe the cover story?,"Wildfires and industry are common sources of polycyclic aromatic hydrocarbons (PAHs).  PAH metabolism determines rates of bioactivation, rates of detoxification, and ultimately risk. We used activity-based protein profiling (ABPP) to characterize cytochrome P450 enzymes in young individuals (≤21 months) compared to adults to assess the potential of early life susceptibility.",C,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,vith,2023_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_2.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_2.png,ave_1,2023_2.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_2.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_2.png,clip,2012_2.txt,train
Nature Chemistry,16_6,Which of the following options best describe the cover story?,"Heterotypic interactions for condensate transition
Various neurodegenerative diseases typically involve amyloid formation, which can develop from condensates that include RNA-binding proteins; however, the underlying molecular mechanism is not entirely clear. It is now evident that, depending on their RNA/protein stoichiometry, these condensates will proceed towards amyloid formation through distinct molecular pathways. The biomolecular condensate on the cover is shown with the texture of a section of its interface shown at a greater resolution to illustrate the droplets' aggregation transition.
See Morelli et al.
Image: Amanda Paganini. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/Nature Chemistry/14_11.png,MAC_Bench/Nature/Cover/Nature Chemistry/14_11.png,vith,14_11.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_6.png,groundtruth,16_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/7_1.png,MAC_Bench/Nature/Cover/Nature Chemistry/7_1.png,clip,7_1.txt,MAC_Bench/Nature/Cover/Nature Chemistry/12_8.png,MAC_Bench/Nature/Cover/Nature Chemistry/12_8.png,vitg,12_8.txt,train
Current Biology,35_3,Which of the following options best describe the cover story?,"On the cover: A little devil frog (Oophaga sylvatica) rests on a leaf on the Ecuadorian rainforest floor. These frogs, like other poison
frogs, sequester alkaloids from their diet of arthropods onto their skin as a defense
against predation. In this issue, Caty et al. demonstrate that these alkaloids also shape the resident skin microbial community
of these frogs. The presence of alkaloids results in a more diverse microbial community,
both taxonomically and metabolically. Photograph © Stephanie Caty; used with permission.",D,MAC_Bench/Cell/Cover/Current Biology/20_23.png,MAC_Bench/Cell/Cover/Current Biology/20_23.png,ave_3,20_23.txt,MAC_Bench/Cell/Cover/Current Biology/29_2.png,MAC_Bench/Cell/Cover/Current Biology/29_2.png,clip,29_2.txt,MAC_Bench/Cell/Cover/Current Biology/35_1.png,MAC_Bench/Cell/Cover/Current Biology/35_1.png,vith,35_1.txt,MAC_Bench/Cell/Cover/Current Biology/35_3.png,MAC_Bench/Cell/Cover/Current Biology/35_3.png,groundtruth,35_3.txt,train
Cell Reports,43_4,Which of the following options best describe the cover story?,"On the cover: Cherries represent the cohesin ATPase domains (SMC3 and SMC1A) undergoing
conformational movements and dimerization upon ATP binding and hydrolysis. These changes
depend upon the presence and binding of RAD21 domains, illustrated as bees. In this
issue, Vitoria Gomes et al. provide structural insights into the dynamics of the cohesin SMC1A and SMC3 ATPase
domains that regulate interactions with DNA. Image credit: Marianne Lemée.",A,MAC_Bench/Cell/Cover/Cell Reports/43_4.png,MAC_Bench/Cell/Cover/Cell Reports/43_4.png,groundtruth,43_4.txt,MAC_Bench/Cell/Cover/Cell Reports/43_11.png,MAC_Bench/Cell/Cover/Cell Reports/43_11.png,vitg,43_11.txt,MAC_Bench/Cell/Cover/Cell Reports/12_11.png,MAC_Bench/Cell/Cover/Cell Reports/12_11.png,vith,12_11.txt,MAC_Bench/Cell/Cover/Cell Reports/18_8.png,MAC_Bench/Cell/Cover/Cell Reports/18_8.png,clip,18_8.txt,train
Science Robotics,9_91,Which of the following options best describe the cover story?,"ONLINE COVER Wearable Shoulder-Assistive Robot. Industrial roles involving repetitive overhead tasks cause shoulder injuries, but existing passive assistive devices are often not adaptive to various user motions. Zhou et al. have now developed a portable soft robot integrated onto a wearable garment to assist the shoulder in industrial work. The robot could reduce muscle activity during various tasks in a laboratory setting. Moreover, in a proof-of-concept study in an automotive industrial setting, qualitative assessment showed its usefulness in static overhead tasks. This month’s cover is an image of a user wearing the assistive robot while holding an object overhead. Credit: Yu Meng Zhou",A,MAC_Bench/Science/Cover/Science Robotics/9_91.png,MAC_Bench/Science/Cover/Science Robotics/9_91.png,groundtruth,9_91.txt,MAC_Bench/Science/Cover/Science Robotics/7_64.png,MAC_Bench/Science/Cover/Science Robotics/7_64.png,vith,7_64.txt,MAC_Bench/Science/Cover/Science Robotics/9_94.png,MAC_Bench/Science/Cover/Science Robotics/9_94.png,vitg,9_94.txt,MAC_Bench/Science/Cover/Science Robotics/5_46.png,MAC_Bench/Science/Cover/Science Robotics/5_46.png,clip,5_46.txt,train
Nature Reviews Nephrology,20_7,Which of the following options best describe the cover story?,"Kidney-targeted nanomedicines, inspired by the Review on p354.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,clip,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,vitg,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,vith,17_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_7.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_7.png,groundtruth,20_7.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_8,Which of the following options best describe the cover story?,"Dietary fibre, inspired by the Review on p301.
Cover design: Sam Whitham",B,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_11.png,vitg,20_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_8.png,groundtruth,21_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_1.png,vith,22_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,clip,21_2.txt,test
Nature Cardiovascular Research,3_3,Which of the following options best describe the cover story?,"Endotheliitis and cardiac dysfunction in long COVID
Thomas et al. use thrombotic vascular tissues and induced pluripotent stem cell-derived cardiac organoids to show that COVID-19-induced vascular endotheliitis and cytokine release disrupt endothelial–cardiomyocyte crosstalk and contribute to cardiac dysfunction in long COVID.
See Thomas et al.
Image: Christina Wu, freelance illustrator. Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_3.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_3.png,groundtruth,3_3.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_8.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_5.png,vith,3_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,clip,1_10.txt,train
Crystal Growth & Design,2024_13,Which of the following options best describe the cover story?,"A calcite, CaCO3, crystal with extensive hopper morphology was synthesized under confinement in the absence of precipitation-modifying additives using an electrochemically assisted deposition at a low negative applied potential in the surface force apparatus. In this process, pH is directly increased inside the confined pore, leading to abundant calcite precipitation in small pore volumes.",A,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_13.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_13.png,groundtruth,2024_13.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,clip,2017_5.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_2.png,vith,2017_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_7.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_7.png,vitg,2017_7.txt,train
Nature Food,5_6,Which of the following options best describe the cover story?,"Marine aquaculture’s carbon footprint
Demand for seafood is projected to rise in the coming decades. While catches from wild fisheries have stagnated, several types of aquaculture production systems have emerged to meet this demand. Marine aquaculture, or mariculture, forms a small part of the aquaculture sector with potential for growth. Climate-friendly farm designs, species selection, low-density operational practices and careful site selection can mitigate potential damage to marine ecosystems and avoid carbon loss. Mariculture’s carbon footprints could be ~40% lower than those of freshwater aquaculture based on fish feed, energy use and the aquatic environment emissions — offering an opportunity for environmentally sustainable seafood production.
See Shen et al.
Image: Abstract Aerial Art/DigitalVision/Getty. Cover design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/Nature Food/5_6.png,MAC_Bench/Nature/Cover/Nature Food/5_6.png,groundtruth,5_6.txt,MAC_Bench/Nature/Cover/Nature Food/1_5.png,MAC_Bench/Nature/Cover/Nature Food/1_5.png,ave_1,1_5.txt,MAC_Bench/Nature/Cover/Nature Food/5_10.png,MAC_Bench/Nature/Cover/Nature Food/5_10.png,ave_3,5_10.txt,MAC_Bench/Nature/Cover/Nature Food/3_5.png,MAC_Bench/Nature/Cover/Nature Food/3_5.png,clip,3_5.txt,test
ACS Applied Materials & Interfaces,2025_8,Which of the following options best describe the cover story?,"Using two-photon phosphorescence lifetime imaging microscopy, the ReI-probe non-invasively tracks wound healing by monitoring collagen regeneration and tissue oxygenation. Bound to collagen, it serves as a density sensor, while unbound probes measure oxygen levels through phosphorescence lifetime changes, enabling simultaneous assessment of the oxygen concentration and collagen content.",B,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_40.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_40.png,vitg,2024_40.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_8.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_8.png,groundtruth,2025_8.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_37.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_37.png,ave_1,2024_37.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_7.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_7.png,clip,2025_7.txt,train
Nature Reviews Endocrinology,21_2,Which of the following options best describe the cover story?,"Mapping progress in cell replacement therapies for T1DM, inspired by the Review on p14.
Cover design: Edward Byrne",C,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_4.png,vith,19_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/21_2.png,groundtruth,21_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,vitg,20_1.txt,val
Nature Microbiology,9_7,Which of the following options best describe the cover story?,"Outcomes of personalized phage therapy
This image shows a bacteriophage on its bacterial host injecting its genome inside the cell where it will reproduce. New bacteriophages burst through the cell wall to find new hosts to infect. In nature, bacteriophages control bacterial populations. Today, they hold potential as a tool in the fight against antimicrobial resistance. A retrospective, observational study reports the efficacy of personalized phage therapy, especially when combined with antibiotics.
See Pirnay et al.
Image: TUMEGGY/SCIENCE PHOTO LIBRARY. Cover design: Debbie Maizels",C,MAC_Bench/Nature/Cover/Nature Microbiology/6_6.png,MAC_Bench/Nature/Cover/Nature Microbiology/6_6.png,clip,6_6.txt,MAC_Bench/Nature/Cover/Nature Microbiology/4_3.png,MAC_Bench/Nature/Cover/Nature Microbiology/4_3.png,vith,4_3.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_7.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_7.png,groundtruth,9_7.txt,MAC_Bench/Nature/Cover/Nature Microbiology/6_4.png,MAC_Bench/Nature/Cover/Nature Microbiology/6_4.png,vitg,6_4.txt,train
Nature Reviews Neurology,20_7,Which of the following options best describe the cover story?,"AI and epilepsy, inspired by the Review on p319.
Cover design: Philip Patenall",A,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_7.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_7.png,groundtruth,20_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_2.png,ave_2,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_10.png,ave_3,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_8.png,clip,20_8.txt,test
Science Robotics,9_95,Which of the following options best describe the cover story?,"ONLINE COVER Special Issue on Robots for Scientific Discovery. Studying honey bees in their native environment is challenging because of their sensitivity to external disturbances. Ulrich et al. developed a robotic system for automated observation of the behavior of honey bees in a comb continuously for a month-long period. The system uses computer vision to intelligently track the queen bee, worker bees, and the brood in nesting cells of the comb. It detected key behavioral metrics at the individual and social level within the colony. This month’s cover is an image of the camera of the robotic system tracking the honey bees on the comb. Credit: Martin Stefanec",A,MAC_Bench/Science/Cover/Science Robotics/9_95.png,MAC_Bench/Science/Cover/Science Robotics/9_95.png,groundtruth,9_95.txt,MAC_Bench/Science/Cover/Science Robotics/5_41.png,MAC_Bench/Science/Cover/Science Robotics/5_41.png,vith,5_41.txt,MAC_Bench/Science/Cover/Science Robotics/8_74.png,MAC_Bench/Science/Cover/Science Robotics/8_74.png,clip,8_74.txt,MAC_Bench/Science/Cover/Science Robotics/9_93.png,MAC_Bench/Science/Cover/Science Robotics/9_93.png,vitg,9_93.txt,train
Trends in Microbiology,32_13,Which of the following options best describe the cover story?,"The reaction center−light-harvesting 1 (RC−LH1) pigment-protein
supercomplex is the central machinery of anoxygenic photosynthesis performed
by purple photosynthetic bacteria and Chloroflexales. This cover image illustrates
various RC−LH1 supercomplex structures from different phototrophic bacteria,
resolved by cryo-EM and X-ray crystallography. In this issue, Liu et al. provide a
comprehensive overview of the recent advances in uncovering the structures and
assembly mechanisms of photosynthetic RC−LH1 complexes. The natural diversity
of RC–LH1 highlights the unique evolutionary strategies utilized by different
phototrophic bacteria for optimizing light-harvesting and electron transfer within
their ecological niches during evolution. Image courtesy: Lu-Ning Liu",C,MAC_Bench/Cell/Cover/Trends in Microbiology/21_10.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_10.png,vitg,21_10.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/28_5.png,MAC_Bench/Cell/Cover/Trends in Microbiology/28_5.png,clip,28_5.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_13.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_13.png,groundtruth,32_13.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/28_4.png,MAC_Bench/Cell/Cover/Trends in Microbiology/28_4.png,vith,28_4.txt,train
Developmental Cell,59_2,Which of the following options best describe the cover story?,"On the cover: Even if tissue-specific multipotent stem cells are damaged and depleted,
the organism possesses the ability to regenerate multipotent stem cells. The cover
image illustrates the recovery process of intestinal stem cells damaged by irradiation
exposure. The image shows in situ hybridization of the small intestine (blue) prepared by a Swiss rolling technique
after irradiation, with stem cells marked by Olfm4 staining, in red. The merged image
with a stopwatch depicts the temporal recovery of intestinal stem cells over time.
To learn more about murine intestinal regeneration following tissue injury, see Ahn et al. Image credit: Sunghwan Bae.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_2.png,MAC_Bench/Cell/Cover/Developmental Cell/59_2.png,groundtruth,59_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/46_1.png,MAC_Bench/Cell/Cover/Developmental Cell/46_1.png,clip,46_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/50_1.png,MAC_Bench/Cell/Cover/Developmental Cell/50_1.png,vitg,50_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/40_4.png,MAC_Bench/Cell/Cover/Developmental Cell/40_4.png,vith,40_4.txt,train
Industrial & Engineering Chemistry Research,2024_49,Which of the following options best describe the cover story?,This cover encourages individuals to overcome their implicit bias and explore the abundant opportunities in STEM. How would we know what we really want until we explore what’s out there? This cover is a part of the ACS-wide DEIR Cover Art program.,B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_43.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_43.png,ave_3,2024_43.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_49.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_49.png,groundtruth,2024_49.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_43.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_43.png,clip,2023_43.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_4.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_4.png,vitg,2021_4.txt,train
Trends in Immunology,45_9,Which of the following options best describe the cover story?,"Our special issue on ‘Neuroimmunology – I’ showcases current research
in this discipline, emphasizing the reciprocal interplay between the brain and our
nervous
systems (central or peripheral). Various cells that act as partners and guardians
of our
nervous and immune systems, e.g., microglia, are highlighted. The articles presented
here unveil key research avenues that may enable a better understanding of neurological
and neuroimmune-related disorders. The cover image reflects the metamorphosis and
tessellation technique developed by Escher; here, a neuron gradually fills in the
gaps
between immune cells, and vice versa. Image credit: Felipe A. Pinho-Ribeiro.",D,MAC_Bench/Cell/Cover/Trends in Immunology/41_5.png,MAC_Bench/Cell/Cover/Trends in Immunology/41_5.png,clip,41_5.txt,MAC_Bench/Cell/Cover/Trends in Immunology/40_7.png,MAC_Bench/Cell/Cover/Trends in Immunology/40_7.png,vitg,40_7.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,vith,36_3.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_9.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_9.png,groundtruth,45_9.txt,train
NATURE REVIEWS GENETICS,26_2,Which of the following options best describe the cover story?,"Inspired by the Review on p7.
Cover design: Patrick Morgan",A,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/26_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/26_2.png,groundtruth,26_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_9.png,clip,15_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,train
ACS Chemical Neuroscience,2025_2,Which of the following options best describe the cover story?,"Nanoconjugates, including 5-FU-PVP and 5-FU-PVP-Au, were synthesized and later functionalized with gold nanoparticles for enhanced therapeutic applications. These nanoconjugates exhibited high drug-loading efficiencies, prolonged drug release, and effective hen egg white lysozyme aggregation inhibition. In an Alzheimer’s Drosophila model, 5-FU-PVP demonstrated superior amyloid aggregation inhibition compared to a bare drug, showcasing potential anti-Alzheimer’s activity. The image was created with the assistance of OpenAI's ChatGPT.",B,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_20.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_20.png,vitg,2024_20.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2025_2.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_24.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_24.png,ave_3,2022_24.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_2.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_2.png,clip,2024_2.txt,train
Nature Reviews Electrical Engineering,1_8,Which of the following options best describe the cover story?,"3D integration of 2D electronics presents an alternative platform for addressing the scaling challenges inherent in silicon-based electronics. Furthermore, this approach facilitates the realization of multifunctional capabilities within a vertically integrated system. The cover image depicts a 3D integrated chip constructed from 2D materials, which enables multifunctionalities such as sensing, logic, and memory. See Das et al.
Image: Jennifer M McCann, Subir Ghosh, Saptarshi Das, The Pennsylvania State University. Cover design: Sam Whitham",D,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,ave_3,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,groundtruth,1_8.txt,test
Developmental Cell,60_1,Which of the following options best describe the cover story?,"On the cover: Sex differences originate early in human postnatal T cell development.
The image represents the different developmental paths male (green) and female (purple)
T cells take during differentiation and training in the thymus. Sex differences in
thymic niches and T cell developmental trajectories are depicted by analogous but
distinct white nodes, representing sex biases in thymic niches, which we identified
using our spatial multi-omics thymus resource. To learn more about how the authors
use spatial multi-omics to identify sex differences in T cell development and thymus
biology, see Stankiewicz et al. Image credit: Jen Ma.",C,MAC_Bench/Cell/Cover/Developmental Cell/37_1.png,MAC_Bench/Cell/Cover/Developmental Cell/37_1.png,vith,37_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/43_5.png,MAC_Bench/Cell/Cover/Developmental Cell/43_5.png,ave_0,43_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/60_1.png,MAC_Bench/Cell/Cover/Developmental Cell/60_1.png,groundtruth,60_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/29_2.png,MAC_Bench/Cell/Cover/Developmental Cell/29_2.png,clip,29_2.txt,train
Cell Metabolism,36_2,Which of the following options best describe the cover story?,"On the cover: In this issue, Liao et al. reveal amino acid as a major carbon supplier for fatty acid synthesis in the liver.
The landscape painting metaphorically illustrates the distinct metabolic fates of
amino acid and carbohydrate: (1) the blue waterfall representing amino acid flux pours
directly into the liver-shaped yellow pool symbolizing hepatic lipid deposition; (2)
the red river depicting glucose flux first drains into a lake portraying glycogen
synthesis, and the remaining branch winds through indirect pathways for conversion
to lactate/acetate before reaching the downstream pool. Illustration by Yilie Liao
and Yun Gu.",C,MAC_Bench/Cell/Cover/Cell Metabolism/28_4.png,MAC_Bench/Cell/Cover/Cell Metabolism/28_4.png,vith,28_4.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_8.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_8.png,clip,36_8.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_2.png,groundtruth,36_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/35_4.png,MAC_Bench/Cell/Cover/Cell Metabolism/35_4.png,ave_1,35_4.txt,val
Trends in Plant Science,29_14,Which of the following options best describe the cover story?,"David G. Robinson and colleagues discuss growing doubts about the
true role of the common mycorrhizal networks (CMN) connecting the roots of trees
in forests. The authors discuss recent work that questions the claim of a substantial
carbon transfer from ‘mother trees’ to their offspring and nearby seedlings through
the
CMN. Current evidence for the ‘mother tree concept’ is inconclusive or absent. The
origin of this concept seems to stem from a desire to humanize plant life but can
lead to
misunderstandings and false interpretations and may eventually harm rather than help
the commendable cause of preserving forests. Image credit: Susanne C. Brink (image:
abstract metal tree sculpture, highlighting trees as engineering masterpieces of nature;
Eisenbaum, https://www.regionalpark-rheinmain.de/portfolio-item/der-eisenbaum/).",B,MAC_Bench/Cell/Cover/Trends in Plant Science/18_5.png,MAC_Bench/Cell/Cover/Trends in Plant Science/18_5.png,vitg,18_5.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_14.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_14.png,groundtruth,29_14.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/17_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/17_1.png,clip,17_1.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/21_3.png,MAC_Bench/Cell/Cover/Trends in Plant Science/21_3.png,vith,21_3.txt,train
ACS Chemical Neuroscience,2024_4,Which of the following options best describe the cover story?,"Vincristine (VCR) is a highly neurotoxic chemotherapy drug. Our study showed that VCR can lead to axonal and neuronal degeneration in the spinal cord of old rats. The histopathological image of the scan that demonstrated the degenerative process in the spinal cord of old rats was used as the cover background. The neurodegeneration demonstrated in the histopathological image shows spherical vacuoles containing macrophages, indicating the phagocytic and neuroinflammatory processes induced by VCR in the spinal cord of aged rats. This unprecedented result may be a key indicator of how VCR may be more neurotoxic to old compared to young individuals, also demonstrating a mechanism that potentially triggers peripheral neuropathy in the elderly. The cover image was generated using Image Creator from Microsoft Designer.",D,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2016_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2016_10.png,vith,2016_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2012_1.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2012_1.png,ave_1,2012_1.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2015_8.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2015_8.png,clip,2015_8.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_4.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_4.png,groundtruth,2024_4.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_9,Which of the following options best describe the cover story?,"Breaking barriers, inspired by the Review on p222.
Cover design: Laura Marshall",C,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_5.png,vith,18_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_12.png,vitg,21_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_9.png,groundtruth,21_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,clip,21_2.txt,train
Industrial & Engineering Chemistry Research,2024_44,Which of the following options best describe the cover story?,"effective acid site density (a proposed parameter that correlates acid strength, density, and micropore volume) allows linking the impacts of different treatments (thermal, acid, alkaline, and agglomeration with bentonite and alumina) with their properties and reaction performance (conversion, yield, and deactivation by coke).",C,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_12.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_12.png,vith,2020_12.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_10.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_10.png,clip,2020_10.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_44.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_44.png,groundtruth,2024_44.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,train
Joule,8_8,Which of the following options best describe the cover story?,"On the cover: The cover image represents a large-area flexible perovskite solar module
(f-PSM) operating outdoors. In this issue of Joule, Lee et al. demonstrate an effective strategy for improving both the efficiency and stability
of f-PSMs by introducing a newly designed electron-transport layer (ETL). This ETL
effectively suppresses the shunt path without sacrificing the electron transport property,
greatly enhancing the efficiency and stability of f-PSMs. Notably, this strategy enables
a record power conversion efficiency (PCE) of 16.4% on f-PSMs (900 cm2). Image credit
: Da Seul Lee.",D,MAC_Bench/Cell/Cover/Joule/3_11.png,MAC_Bench/Cell/Cover/Joule/3_11.png,ave_0,3_11.txt,MAC_Bench/Cell/Cover/Joule/3_8.png,MAC_Bench/Cell/Cover/Joule/3_8.png,vith,3_8.txt,MAC_Bench/Cell/Cover/Joule/6_12.png,MAC_Bench/Cell/Cover/Joule/6_12.png,clip,6_12.txt,MAC_Bench/Cell/Cover/Joule/8_8.png,MAC_Bench/Cell/Cover/Joule/8_8.png,groundtruth,8_8.txt,train
NATURE GENETICS,56_4,Which of the following options best describe the cover story?,"Peanut global phenotypic variation
Chloroplast and whole-genome sequencing of Arachis accessions sheds light on peanut evolutionary history and phenotypic diversification.
See Zheng et al.
Image: Nastasic/DigitalVision Vectors/Getty. Cover design: Laoise Mac Gabhann.",C,MAC_Bench/Nature/Cover/NATURE GENETICS/55_9.png,MAC_Bench/Nature/Cover/NATURE GENETICS/55_9.png,vith,55_9.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/54_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/54_1.png,clip,54_1.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_4.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_4.png,groundtruth,56_4.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/51_4.png,MAC_Bench/Nature/Cover/NATURE GENETICS/51_4.png,vitg,51_4.txt,val
Nature Reviews Physics,6_8,Which of the following options best describe the cover story?,"The cover of this issue refers to the new collection `Physics as a Human Endeavour’. See Editorial
Cover design: Susanne Harris.",D,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_9.png,vith,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_3.png,vitg,1_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_8.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_8.png,groundtruth,6_8.txt,train
Nature Aging,4_9,Which of the following options best describe the cover story?,"mTOR, inflammaging and longevity
In this issue, Pingze Zhang et al. reveal that S6K suppression in the fruit-fly fat body mediates the longevity effects of rapamycin, and uncover a sex-dimorphic link through to lysosome morphology and inflammation, via Syntaxin 13. The cover image conceptualizes the link to inflammaging by depicting aged flies as confined to a jar (representing the nuclear localization of the Drosophila NFκB-like transcription factor Relish), emitting brighter light (representing upregulation of inflammatory mediators).
See Zhang et al.
Image: Bruna Di Giacomo, Independent Artist. Cover Design: Lauren Heslop",D,MAC_Bench/Nature/Cover/Nature Aging/3_7.png,MAC_Bench/Nature/Cover/Nature Aging/3_7.png,vith,3_7.txt,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,vitg,1_4.txt,MAC_Bench/Nature/Cover/Nature Aging/2_1.png,MAC_Bench/Nature/Cover/Nature Aging/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Aging/4_9.png,MAC_Bench/Nature/Cover/Nature Aging/4_9.png,groundtruth,4_9.txt,train
Nature Climate Change,15_1,Which of the following options best describe the cover story?,"Observing a smoother Arctic
As sea ice moves around it can experience deformation and form pressure ridges, which in turn can affect the atmospheric circulation and support ecosystems. Writing in this issue of Nature Climate Change, Krumpen and colleagues use airborne observations to show that the number of pressure ridges has declined in recent decades, mainly due to a loss of older ice.
See Krumpen et al. and News & Views Maksym
Image: Andreas Preusser, Alfred Wegener Institute. Cover design: Vanitha Selvarajan",C,MAC_Bench/Nature/Cover/Nature Climate Change/9_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/9_10.png,clip,9_10.txt,MAC_Bench/Nature/Cover/Nature Climate Change/8_12.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_12.png,vith,8_12.txt,MAC_Bench/Nature/Cover/Nature Climate Change/15_1.png,MAC_Bench/Nature/Cover/Nature Climate Change/15_1.png,groundtruth,15_1.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_4.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_4.png,vitg,14_4.txt,train
Trends in Cancer,10_7,Which of the following options best describe the cover story?,"An immune rich microenvironment correlates with improved outcomes
for patients with breast cancer and response to chemotherapies, forming the rationale
for T cell-based immunotherapies in the treatment of some forms of breast cancer.
In this issue, Rayson et al. review the composition of the immune infiltrates in breast
cancer and discuss its pertinent role in identifying biomarkers for immune checkpoint
blockade and for effective combination therapy strategies. The cover represents a
tumor microenvironment (garden) filled with a variety of immune cell types (flower
variety) that contribute to the tumor’s growth or suppression. Image courtesy of
gettyimages/Pobytov.",B,MAC_Bench/Cell/Cover/Trends in Cancer/7_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/7_4.png,vith,7_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_7.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_7.png,groundtruth,10_7.txt,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,vitg,3_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/4_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_1.png,clip,4_1.txt,train
NATURE REVIEWS MICROBIOLOGY,22_5,Which of the following options best describe the cover story?,"Coral microbiomes in a changing world, inspired by the Review on p460
Cover design: Amie Fernandez",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_12.png,ave_2,14_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/17_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/17_8.png,vitg,17_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_1.png,clip,19_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_5.png,groundtruth,22_5.txt,test
NATURE REVIEWS MICROBIOLOGY,22_12,Which of the following options best describe the cover story?,"Disinfection, inspired by the Review on p4.
Cover design: Philip Patenall.",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/13_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/13_6.png,vith,13_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_8.png,vitg,22_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_12.png,groundtruth,22_12.txt,test
Cell Metabolism,37_2,Which of the following options best describe the cover story?,"On the cover: In this issue, Li et al. develop a high-performance biosensor for arginine, named STAR, which lights up arginine's
functional diversity in physiology and pathology. The cover image is an original artwork
depicting a night sky, resembling the unexplored mystery of arginine metabolism. The
bright stars, arranged in the pattern of the arginine molecular formula, light up
the night sky, which stands for the excellent ability of the STAR sensor in illuminating
arginine metabolism. Artwork by Qing Zhang and Yaqiong Chen.",A,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,groundtruth,37_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_3.png,ave_3,36_3.txt,MAC_Bench/Cell/Cover/Cell Metabolism/37_1.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_1.png,clip,37_1.txt,MAC_Bench/Cell/Cover/Cell Metabolism/17_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/17_5.png,ave_2,17_5.txt,train
NATURE REVIEWS NEUROSCIENCE,25_7,Which of the following options best describe the cover story?,"‘Converging pathways in Parkinson disease’, inspired by the Review on p393.
Cover design: Jennie Vallis",B,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_8.png,vitg,24_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_7.png,groundtruth,25_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_5.png,vith,22_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_5.png,clip,14_5.txt,train
Trends in Cognitive Sciences,29_2,Which of the following options best describe the cover story?,"Habits emerge from the interplay between two brain systems: a stimulus-response
(S–R) system that promotes the repetition of familiar actions, and a goal-directed
system that emphasizes flexibility and planning. Achieving the right balance between
these systems is essential, as disruptions can lead to action slips, impulsive behaviors,
or compulsions. In this issue of Trends in Cognitive Sciences, Eike K. Buabang and
colleagues explore how recent insights into these competing mechanisms can enhance
our ability to make and break habits. Building on these insights, they explore practical
applications for daily life and interventions for clinical populations affected by
imbalances
between these two systems. Cover art from Malte Mueller/Getty Images.",B,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/24_3.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/24_3.png,vitg,24_3.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/29_2.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/29_2.png,groundtruth,29_2.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/21_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/21_1.png,ave_0,21_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_10.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_10.png,clip,18_10.txt,val
ACS ES&T Water,2024_5,Which of the following options best describe the cover story?,"The present work explores and demonstrates the electrochemical sensing capability of a highly stable bimetallic gold–copper nanocluster. The nanocluster can selectively sense heavy metal ion lead, Pb(II) through a specific gold–Pb(II) interaction, and is successfully extended to real sample analysis as well. Thus, a real-time monitoring strategy has been put forward.",A,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_5.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_3.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_3.png,vith,2021_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_6.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_6.png,vitg,2022_6.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_1.png,clip,2021_1.txt,train
Trends in Immunology,45_13,Which of the following options best describe the cover story?,"Two articles in this issue, by Carrie Lucas and the STAT6 Gain-of-Function International
Consortium, respectively, discuss human inborn errors of immunity. For instance, the
STAT6 Gain-of-Function International Consortium (Stuart Turvey and colleagues) address
how recent findings and mechanisms of STAT6 germline heterozygous gain-of-function
rare variants cause a broad and severe clinical phenotype of early-onset, multi-system
human allergic disease. New findings of human inborn errors of immunity may help identify
possible targeted treatment approaches. Image credit: GettyImages.",D,MAC_Bench/Cell/Cover/Trends in Immunology/38_5.png,MAC_Bench/Cell/Cover/Trends in Immunology/38_5.png,clip,38_5.txt,MAC_Bench/Cell/Cover/Trends in Immunology/35_10.png,MAC_Bench/Cell/Cover/Trends in Immunology/35_10.png,vith,35_10.txt,MAC_Bench/Cell/Cover/Trends in Immunology/39_2.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_2.png,vitg,39_2.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_13.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_13.png,groundtruth,45_13.txt,train
Cell Reports Methods,4_8,Which of the following options best describe the cover story?,"On the cover: In this issue, Kim et al. combine a black box optimizer with a white box logical model to create a gray box
framework for predicting anti-cancer drug responses. The cover image depicts silver
cubes representing the gray box framework. Cover image courtesy gettyimages/Iana Kunitsa.",A,MAC_Bench/Cell/Cover/Cell Reports Methods/4_8.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_8.png,groundtruth,4_8.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,vitg,2_11.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_3.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_3.png,clip,3_3.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_10.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_10.png,vith,4_10.txt,train
Trendsin Neurosciences,47_6,Which of the following options best describe the cover story?,"Intrinsically generated bursts of neural activity induce maturation of
auditory neurons and shape the organization of future sound processing circuits during
an early developmental period, before acoustic information is transmitted to the inner
ear. In this issue of Trends in Neurosciences, Calvin Kersbergen and Dwight Bergles
discuss the molecular mechanisms responsible for spontaneous activity generation
within the developing cochlea and the functional roles of the resulting highly patterned
neural activity in promoting auditory circuit refinement and maturation. The cover
image
reflects the distinct spatial pattern of neural activation to varying sound pitch,
as shown
by distinct colors, within the auditory cortex of a mouse following ear canal opening
and
hearing onset. Image credit: Calvin Kersbergen.",B,MAC_Bench/Cell/Cover/Trendsin Neurosciences/46_8.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/46_8.png,vitg,46_8.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_6.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_6.png,groundtruth,47_6.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_10.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_10.png,vith,47_10.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/45_7.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/45_7.png,clip,45_7.txt,train
ACS Nano,2025_7,Which of the following options best describe the cover story?,"Optical forces are utilized to enable the rapid and controllable transport of subcellular structures, such as organelles, within the natural tunneling nanotube structures between cells, which serve as biological conveyor belts.",B,MAC_Bench/ACS/Cover/ACS Nano/2024_38.png,MAC_Bench/ACS/Cover/ACS Nano/2024_38.png,clip,2024_38.txt,MAC_Bench/ACS/Cover/ACS Nano/2025_7.png,MAC_Bench/ACS/Cover/ACS Nano/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/ACS Nano/2016_1.png,MAC_Bench/ACS/Cover/ACS Nano/2016_1.png,vitg,2016_1.txt,MAC_Bench/ACS/Cover/ACS Nano/2018_2.png,MAC_Bench/ACS/Cover/ACS Nano/2018_2.png,ave_2,2018_2.txt,train
Nature Computational Science,4_3,Which of the following options best describe the cover story?,"Anomalous diffusion via deep learning
The diffusion of particles in real-world settings and complex environments often exhibits nonlinear and unstable properties, also known as anomalous diffusion. While mathematical models have been proposed to describe the different features that give rise to anomalous diffusion, characterizing anomalous diffusions with unknown features remains challenging. In this issue, Yongbing Zhang, Xiangyang Ji and colleagues introduce a deep learning approach for anomalous diffusion recognition that is robust for observed trajectories that are in-distribution samples (meaning, covered by the training distribution), as well as out-of-distribution samples (meaning, not originally found in the training dataset). The cover image depicts a diffusion phenomenon within a black-box medium.
See Xiaochen Feng et al. and Adrian Pacheco-Pozo and Diego Krapf
Image: Courtesy of Yongbing Zhang, Harbin Institute of Technology (Shenzhen). Cover design: Alex Wing.",D,MAC_Bench/Nature/Cover/Nature Computational Science/4_6.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_6.png,clip,4_6.txt,MAC_Bench/Nature/Cover/Nature Computational Science/2_3.png,MAC_Bench/Nature/Cover/Nature Computational Science/2_3.png,vith,2_3.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_9.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_3.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_3.png,groundtruth,4_3.txt,train
Molecular Plant,17_11,Which of the following options best describe the cover story?,"On the cover: Understanding the origin of crops is crucial for their breeding and genetic modification.
Despite of considerable efforts for decades, attempting to generate artificial hexaploids
from diploid and tetraploid wild relatives of sweetpotato has been unsuccessful, probably
because the progenitor species of cultivated sweetpotato still remains unclear. In
this issue, by using multiple genetic and genomic approaches Yan et al. have identified
two probable progenitors and unraveled the genetic backstory about the formation of
cultivated sweetpotato. Just as depicted on the cover image, the study by Yan et al.
closely resembles performing a paternity test to establish a genetic link between
cultivated sweetpotato and their progenitors. Image by Mengxiao Yan and Yukun Hao
with the assistance of DALL·E 3 (https://openai.com/dall-e-3).",C,MAC_Bench/Cell/Cover/Molecular Plant/12_11.png,MAC_Bench/Cell/Cover/Molecular Plant/12_11.png,ave_2,12_11.txt,MAC_Bench/Cell/Cover/Molecular Plant/12_12.png,MAC_Bench/Cell/Cover/Molecular Plant/12_12.png,clip,12_12.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_11.png,MAC_Bench/Cell/Cover/Molecular Plant/17_11.png,groundtruth,17_11.txt,MAC_Bench/Cell/Cover/Molecular Plant/14_9.png,MAC_Bench/Cell/Cover/Molecular Plant/14_9.png,vith,14_9.txt,train
NATURE REVIEWS DRUG DISCOVERY,24_1,Which of the following options best describe the cover story?,"N-of-1 therapies, inspired by the Review on p40.
Cover design: S. Harris",D,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_12.png,vitg,21_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/24_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/24_1.png,groundtruth,24_1.txt,train
ACS Applied Electronic Materials,2025_1,Which of the following options best describe the cover story?,Two-dimensional (2D) materials-coated paper-based helical origami triboelectric nanogenerators (O-TENGs) are designed to harvest blue energy. The efficient charge transfer between the cellulose and 2D materials significantly improves the output performance of the O-TENGs. This,D,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2024_5.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2024_5.png,clip,2024_5.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2022_4.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2022_4.png,vitg,2022_4.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_2.png,vith,2025_2.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_1.png,groundtruth,2025_1.txt,train
ACS Engineering Au,2024_3,Which of the following options best describe the cover story?,"Ammonia selective catalytic reduction (NH3-SCR) has been extensively applied for NOx emission control, where the formation of the greenhouse gas N2O is an issue.",D,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_1.png,ave_1,2021_1.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_2.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_2.png,vith,2021_2.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_3.png,groundtruth,2024_3.txt,train
Nature Ecology & Evolution,8_5,Which of the following options best describe the cover story?,"Brittle star genome
Amphiura filiformis is a brittle star species that lives in burrows in the seabed. It extends its serpent-like arms to suspension-feed on plankton, which leaves the arms vulnerable to a wide range of predators. As an adaptation to this lifestyle, this species has evolved impressive arm regeneration abilities. The brittle star genome sheds light on the molecular basis of this efficient regeneration process.
See Parey et al
Image: Fredrik Pleijel. Cover Design: Vanitha Selvarajan.",B,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/6_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/6_1.png,vitg,6_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_5.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_5.png,groundtruth,8_5.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/7_4.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/7_4.png,ave_3,7_4.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_8.png,clip,5_8.txt,val
ACS Applied Materials & Interfaces,2025_2,Which of the following options best describe the cover story?,"This cover art depicts a conceptual visualization of an advanced imaging system, featuring an array of microbolometers interfaced with a nanostructured graphene material. The graphic represents high-speed data processing and the dynamic interaction between the microbolometer array and terahertz radiation at the nanoscale.",D,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2017_20.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2017_20.png,vith,2017_20.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_2.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_2.png,ave_2,2024_2.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2019_12.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2019_12.png,clip,2019_12.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_2.png,groundtruth,2025_2.txt,train
One Earth,7_5,Which of the following options best describe the cover story?,"On the cover: Our cities are growing hotter. An urban heat island effect, augmented
by climate change, is creating stifling and dangerous conditions in urban centers,
and cooling solutions are at a premium. Air conditioning units, the go-to solution,
are expensive, energy hungry, and can release problematic refrigerants. Ballyscanlon,
Getty.",B,MAC_Bench/Cell/Cover/One Earth/1_1.png,MAC_Bench/Cell/Cover/One Earth/1_1.png,clip,1_1.txt,MAC_Bench/Cell/Cover/One Earth/7_5.png,MAC_Bench/Cell/Cover/One Earth/7_5.png,groundtruth,7_5.txt,MAC_Bench/Cell/Cover/One Earth/7_8.png,MAC_Bench/Cell/Cover/One Earth/7_8.png,vith,7_8.txt,MAC_Bench/Cell/Cover/One Earth/6_2.png,MAC_Bench/Cell/Cover/One Earth/6_2.png,vitg,6_2.txt,val
Bioconjugate Chemistry,2024_8,Which of the following options best describe the cover story?,"A super-hydrophilic zwitterionic material, EKP polypeptide, was employed to cloak yeast cells via genetic engineering. This polypeptide serves to shield yeast cells from interactions with yeast-specific antibodies and macrophage cells. This approach endows these cloaked yeast cells with the potential to circumvent the immune system.",C,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_10.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_10.png,vitg,2013_10.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,clip,2010_3.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_8.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2017_1.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2017_1.png,vith,2017_1.txt,val
Developmental Cell,59_17,Which of the following options best describe the cover story?,"On the cover: “Break the cocoon into a butterfly”: a diagrammatic representation of
cell fate transitions during trans-differentiation in the mouse embryo. The intact
cocoon, broken cocoon, and flying butterfly represent initial, transition, and terminal
states of trans-differentiation, respectively. Breaking the cocoon represents a lineage
barrier being overcome, triggered by certain stresses, such as inflammatory signal-mediated
developmental stress. To learn more about the role of inflammatory signaling in triggering
trans-differentiation events in the mouse embryo, see Zhang et al. Image credit: Feng Liu.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_17.png,MAC_Bench/Cell/Cover/Developmental Cell/59_17.png,groundtruth,59_17.txt,MAC_Bench/Cell/Cover/Developmental Cell/58_2.png,MAC_Bench/Cell/Cover/Developmental Cell/58_2.png,clip,58_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/37_6.png,MAC_Bench/Cell/Cover/Developmental Cell/37_6.png,vitg,37_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/24_5.png,MAC_Bench/Cell/Cover/Developmental Cell/24_5.png,vith,24_5.txt,test
Nature Chemical Engineering,1_7,Which of the following options best describe the cover story?,"Scaling up tandem CO2 electrolysis
Tandem CO2 electrolysis converts CO2 into multi-carbon products by employing different reaction environments in each electrolysis cell. This enabling technology can produce valuable chemicals and fuels, but more effort is needed in scaling these systems to commercial levels. Now, Feng Jiao and colleagues address this critical need by demonstrating tandem CO2 electrolysis at the kilowatt scale, marking a major step towards real-world implementation of these systems. The cover shows the tandem CO2 electrolyzer used in this study.
See Crandall et al. and Liu et al.
Image: Bradie S. Crandall, University of Delaware. Cover design: Thomas Phillips.",B,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,groundtruth,1_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_2.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_2.png,vith,1_2.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,clip,1_9.txt,test
ACS Applied Polymer Materials,2024_22,Which of the following options best describe the cover story?,"The top right is hexagons representing the benzene ring, which is an important part of the TPU. The central part of the cover is a three-dimensional diagram of the sandwich structure. The left side is a microscopic diagram of particle-filled TPU film and nonwovens.",A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_22.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png,vitg,2024_4.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_6.png,clip,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_4.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_4.png,vith,2022_4.txt,train
Nature Reviews Earth & Environment,5_8,Which of the following options best describe the cover story?,"Tectonic processes can lead to the formation of semi-enclosed seas and the deposition of extensive salt deposits. This Review explores the drivers and impacts of the Mediterranean Messinian salinity crisis, including previously unconsidered impacts on the global carbon cycle.
Image credit: Nick Brundle Photography/Getty images. Cover design: Carl Conway.",A,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_8.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_8.png,groundtruth,5_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_12.png,clip,2_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_4.png,vith,2_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_1.png,vitg,1_1.txt,val
NATURE MEDICINE,30_4,Which of the following options best describe the cover story?,"Immunotherapy for Parkinson’s disease
In this issue, Eijsvogel et al. share the results of a phase 1 study that investigated the safety, tolerability and immunogenicity of UB-312 (an immunotherapeutic that targets pathological α-synuclein) in people with Parkinson’s disease. The cover shows a neuron being drawn by a blue pen, representing the long-term, potentially restorative and regenerative effects an immunotherapy (such as UB-312) may have for those with Parkinson’s disease.
See Eijsvogel et al.
Image: Noémie Dodart. Cover design: Marina Spence",A,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_4.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_4.png,groundtruth,30_4.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/16_2.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/16_2.png,vith,16_2.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/15_12.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/15_12.png,ave_2,15_12.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/12_2.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/12_2.png,clip,12_2.txt,train
Current Biology,34_1,Which of the following options best describe the cover story?,"On the cover: In this issue, Smith et al. show that honey bees symmetrically stockpile their nest contents, creating mirror-image
symmetry within the nest. This architectural symmetry is colony-specific and is present
throughout a colony's life. Curiously, even when independent colonies stockpile opposite
sides of a comb, they still create a mirror image. The researchers then show that
temperature is a critical cue for positioning brood and that symmetry provides adaptive
benefits to the colony. Finally, they show that nest symmetry exists across all species
of Apis. Uniting investigations across all four of Tinbergen's Questions, this work shows
that there are behavioral processes that create functional symmetry in the collective
organization of animal architecture. Photograph by Peter R. Marting.",D,MAC_Bench/Cell/Cover/Current Biology/25_9.png,MAC_Bench/Cell/Cover/Current Biology/25_9.png,ave_3,25_9.txt,MAC_Bench/Cell/Cover/Current Biology/19_14.png,MAC_Bench/Cell/Cover/Current Biology/19_14.png,clip,19_14.txt,MAC_Bench/Cell/Cover/Current Biology/27_18.png,MAC_Bench/Cell/Cover/Current Biology/27_18.png,ave_2,27_18.txt,MAC_Bench/Cell/Cover/Current Biology/34_1.png,MAC_Bench/Cell/Cover/Current Biology/34_1.png,groundtruth,34_1.txt,train
Journal of Medicinal Chemistry,2024_21,Which of the following options best describe the cover story?,This research utilizes phytochemical nanoparticles loaded on 3D-printed tricalcium phosphate scaffolds for the treatment of critical bone defects.,D,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_2.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_2.png,ave_2,2022_2.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_16.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_16.png,vitg,2022_16.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_4.png,clip,2017_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_21.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_21.png,groundtruth,2024_21.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_3,Which of the following options best describe the cover story?,"‘Endosomes as sorting stations’, inspired by the Review on p765
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_11.png,vitg,21_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_3.png,groundtruth,25_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_3.png,clip,22_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_4.png,vith,23_4.txt,train
Inorganic Chemistry,2025_1,Which of the following options best describe the cover story?,"The crystal field splitting of neodymium(III) is determined by the full electrostatic potential of the donor atoms, which for water requires a description of the orientation of all nine coordinating donor ligands. Or briefly, the properties of lanthanide(III) aqua ions are defined by the shape of water.",B,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_24.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_24.png,vith,2024_24.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2022_43.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2022_43.png,clip,2022_43.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_12.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_12.png,vitg,2024_12.txt,val
Nature Metabolism,6_6,Which of the following options best describe the cover story?,"Nuclear moonlighting
The urea cycle enzyme argininosuccinate synthase (ASS1) translocates to the nucleus upon DNA damage, thus restraining cytosolic pyrimidine synthesis and producing nuclear fumarate to drive cell cycle arrest and subsequent genome repair. The image depicts the moonlighting function of ASS1.
See Lim et al.
Image: Grant Faint/Getty Images. Cover design: Thomas Phillips",B,MAC_Bench/Nature/Cover/Nature Metabolism/5_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/5_9.png,vitg,5_9.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_6.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_6.png,groundtruth,6_6.txt,MAC_Bench/Nature/Cover/Nature Metabolism/2_8.png,MAC_Bench/Nature/Cover/Nature Metabolism/2_8.png,vith,2_8.txt,MAC_Bench/Nature/Cover/Nature Metabolism/1_1.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_1.png,clip,1_1.txt,train
NATURE MATERIALS,23_4,Which of the following options best describe the cover story?,"Moiré superlattices in twisted perovskites
Moiré superlattices in twisted two-dimensional halide perovskites are realized, revealing the emergence of localized bright excitons with enhanced emissions and trapped charge carriers.
See Zhang et al.
Image: Shuchen Zhang, Purdue University. Cover design: Alex Whitworth.",C,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_8.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_8.png,vitg,20_8.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_2.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_2.png,ave_1,22_2.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_4.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_4.png,groundtruth,23_4.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/14_11.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/14_11.png,clip,14_11.txt,train
The Journal of Physical Chemistry C,2025_9,Which of the following options best describe the cover story?,"Collage of artwork from recent issues of J. Phys. Chem. C. Background: Light-Induced Increase of the Local Molecular Coverage on a Surface (J. Phys. Chem. C 2024, 128 (14), 5919–5926. DOI: 10.1021/acs.jpcc.4c00559). Clockwise from top left: Effects of Pore Arrangement of TiO2-Coated Porous Alumina Membranes on Photocatalytic Properties (J. Phys. Chem. C 2024, 128 (15), 6478–6486. DOI: 10.1021/acs.jpcc.4c01029); Quantum Dot Fluorescent Imaging: Using Atomic Structure Correlation Studies to Improve Photophysical Properties (J. Phys. Chem. C 2024, 128 (9), 3632–3640. DOI: 10.1021/acs.jpcc.3c07367); Ultrafast Energy Funneling in Two-Dimensional Mixed-Halide Perovskites Caused by Intrinsic Halide Immiscibility (J. Phys. Chem. C 2024, 128 (1), 279–286. DOI: 10.1021/acs.jpcc.3c07170). In Situ Tracked Hybridization Phenomenon of Gold Nanorods in Monolayer Systems (J. Phys. Chem. C 2024, 128 (14), 6065–6071. DOI: 10.1021/acs.jpcc.3c08164); Tailoring the Reaction Pathway for Control of Size and Composition of Silver–Gold Alloy Nanoparticles (J. Phys. Chem. C 2024, 128 (21), 8660–8671. DOI: 10.1021/acs.jpcc.4c00321).",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2018_38.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2018_38.png,clip,2018_38.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_9.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_9.png,groundtruth,2025_9.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2022_29.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2022_29.png,vith,2022_29.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2024_4.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2024_4.png,vitg,2024_4.txt,test
Journal of the American Chemical Society,2024_50,Which of the following options best describe the cover story?,"An environmentally benign and economic method was established to synthesize the NiOOH active phase. Mechanistic insights led to milestone activities, yielding directional electrochemical conversion of the lignin-derived cyclohexanol to cyclohexanone and of cyclohexanone to adipic acid by accurately controlling the Ni3+",D,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_7.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_7.png,clip,2010_7.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_13.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_13.png,vith,2017_13.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,vitg,2010_30.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_50.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_50.png,groundtruth,2024_50.txt,train
Molecular Therapy,32_13,Which of the following options best describe the cover story?,"On the cover:Clarke et al. showed multi-organ antisense oligonucleotide (ASO) distribution in a mouse embryo
section after a single in utero amniotic fluid injection. Notably high ASO density is seen in the brain of this embryo,
as well as in the liver, lung, heart, and gastrointestinal tract. This whole mouse
embryo, gestational day e18.5, sagittal section was stained by mi-RNA in-situ hybridization, showing detection of an ASO, with regional ASO density displayed as
a heat map (purple = low, red = high). Image credit: David Young, Maria T. Clarke,
and Danielle J. Tan.",C,MAC_Bench/Cell/Cover/Molecular Therapy/28_1.png,MAC_Bench/Cell/Cover/Molecular Therapy/28_1.png,clip,28_1.txt,MAC_Bench/Cell/Cover/Molecular Therapy/30_16.png,MAC_Bench/Cell/Cover/Molecular Therapy/30_16.png,vitg,30_16.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_13.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_13.png,groundtruth,32_13.txt,MAC_Bench/Cell/Cover/Molecular Therapy/25_1.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_1.png,vith,25_1.txt,test
BDJ In Practice,37_9,Which of the following options best describe the cover story?,"Volume 37 | Issue 4 | April
This themed edition of BDJ In Practice takes a deep dive into the recruitment and retention market as it stands today. With deep-rooted problems stemming back a number of years, what does the outlook look like for the profession?
Cover illustration by Tim Marrs",D,MAC_Bench/Nature/Cover/BDJ In Practice/33_12.png,MAC_Bench/Nature/Cover/BDJ In Practice/33_12.png,vitg,33_12.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,ave_2,36_1.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_10.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_10.png,clip,35_10.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_9.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_9.png,groundtruth,37_9.txt,train
NATURE REVIEWS CANCER,24_3,Which of the following options best describe the cover story?,"Persistence through adversity, inspired by the Roadmap on p694.
Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_3.png,groundtruth,24_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_1.png,ave_1,25_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_1.png,vitg,23_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,clip,25_2.txt,train
Med,5_9,Which of the following options best describe the cover story?,"On the cover: Camrelizumab, an anti-PD-1 immunotherapy drug, shows promise in treating
a range of cancers, including hepatocellular carcinoma, esophageal squamous cell carcinoma,
and Hodgkin lymphoma. In a phase 2 clinical trial, Pan et al. demonstrated the safety and feasibility of pre-operative camrelizumab with microwave
ablation for treating early breast cancer. The combined therapy enhanced the cytotoxic
and effector memory functions of peripheral CD8+ T cells. The treatment also activated MHC class I and interferon signaling pathways
in monocytes, suggesting their contribution to the improved CD8+ T cell activity. Cover credit: JUAN GARTNER/Science Photo Library via Getty Images.",A,MAC_Bench/Cell/Cover/Med/5_9.png,MAC_Bench/Cell/Cover/Med/5_9.png,groundtruth,5_9.txt,MAC_Bench/Cell/Cover/Med/6_1.png,MAC_Bench/Cell/Cover/Med/6_1.png,vitg,6_1.txt,MAC_Bench/Cell/Cover/Med/4_6.png,MAC_Bench/Cell/Cover/Med/4_6.png,vith,4_6.txt,MAC_Bench/Cell/Cover/Med/2_4.png,MAC_Bench/Cell/Cover/Med/2_4.png,clip,2_4.txt,train
ACS Polymers Au,2025_1,Which of the following options best describe the cover story?,"Severe aggregation of DNA origami is seen when oligolysine-1K PEG coatings are used (green), but in proper environmental conditions, the",C,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,ave_2,2023_4.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,vitg,2023_6.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2022_3.png,clip,2022_3.txt,train
ACS ES&T Water,2024_11,Which of the following options best describe the cover story?,"This captivating cover art symbolizes the complex interplay of factors driving eutrophication in freshwater ecosystems. The artwork illustrates the intricate relationship among environmental variables, sediment nutrient release, and microbial communities in West Lake, revealing the critical role of submerged plants and microbial diversity in shaping nutrient dynamics. This comprehensive study sheds light on the dynamics of internal nutrient loading, providing insights crucial for effective ecosystem management and water quality preservation.",A,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_11.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_1.png,ave_3,2021_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,ave_2,2025_1.txt,train
Acta Pharmacologica Sinica,45_4,Which of the following options best describe the cover story?,"Cover Credit: Methionine-choline deficient diet (MCD) has been widely illustrated in inducing persistent alterations of gut microbiota and metabolome during hepatitis. Given the close interaction between gut and liver disorders, this study further highlights that intake of MCD predisposes to experimental colitis and enhances its pathogenesis via modulating gut microbes and macrophages. (Doi: 10.1038/s41401-024-01291-y). See the article in pages 1912-1925.",A,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_4.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_4.png,groundtruth,45_4.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_5.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_5.png,vitg,44_5.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_1.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_1.png,clip,42_1.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_6.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_6.png,vith,42_6.txt,train
NATURE MATERIALS,23_6,Which of the following options best describe the cover story?,"Reprogrammable on-chip topological photonics
By harnessing the large-scale integration of rapidly reprogrammable silicon photonic nanocircuits and microresonators, diverse topological photonic multifunctionalities are implemented and dynamically transformed on-chip.
See Dai et al.
Image: Tianxiang Dai and Jianwei Wang, Peking University Cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_1.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_1.png,ave_1,22_1.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_6.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_6.png,groundtruth,23_6.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_2.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_2.png,vitg,22_2.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_1.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_1.png,clip,21_1.txt,train
Biophysical Reports,4_3,Which of the following options best describe the cover story?,"On the cover: Tetraspanin proteins (TSPANs) are found in all cell types and are involved in functions
like cell adhesion, membrane fusion, and cancer metastasis, mainly through their ability
to form higher-order structures. Their assembly depends on membrane concentration,
which can increase in curved membranes for some tetraspanins because of their sensitivity
to membrane curvature. To understand how different parts of the protein contribute
to its assembly and curvature sensitivity, micropipette aspiration combined with confocal
microscopy and optical tweezers was used. The illustration depicts a vesicle containing
TSPAN4 proteins held in a micropippete, with a membrane tube pulled from it by using
an optically trapped bead. Upon tube formation, the proteins partition into the tube.
By using this assay, it was demonstrated that the protein's extracellular loop 2 contributes
to the curvature sensitivity and curvature-induced interactions of TSPAN4. DOI: https://doi.org/10.1016/j.bpr.2024.100149",C,MAC_Bench/Cell/Cover/Biophysical Reports/3_1.png,MAC_Bench/Cell/Cover/Biophysical Reports/3_1.png,ave_3,3_1.txt,MAC_Bench/Cell/Cover/Biophysical Reports/1_1.png,MAC_Bench/Cell/Cover/Biophysical Reports/1_1.png,vitg,1_1.txt,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,groundtruth,4_3.txt,MAC_Bench/Cell/Cover/Biophysical Reports/2_3.png,MAC_Bench/Cell/Cover/Biophysical Reports/2_3.png,clip,2_3.txt,train
Nature Reviews Physics,6_2,Which of the following options best describe the cover story?,"The cover of this issue illustrates the physics of freezing and melting. See Sun & Calzavarini.
Image: Galaxiid/Alamy Stock Photo. Cover design: Susanne Harris.",A,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_2.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_2.png,groundtruth,6_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png,vitg,6_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_8.png,vith,1_8.txt,train
Nature Climate Change,14_7,Which of the following options best describe the cover story?,"Birds aid forest restoration
Forest restoration has gained global interest as a tool to increase carbon storage, while also improving biodiversity and human well-being. Writing in this issue, Bello and colleagues investigate the role of seed-dispersing frugivores in determining species composition and carbon storage potential in regenerating forests. They show that large birds disperse seeds with higher storage potential, but that movement of these birds can be largely limited by forest fragmentation.
See Bello et al.
Image: Mathias M. Pires, Universidade Estadual de Campinas. Cover design: Debbie Maizels",A,MAC_Bench/Nature/Cover/Nature Climate Change/14_7.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_7.png,groundtruth,14_7.txt,MAC_Bench/Nature/Cover/Nature Climate Change/13_6.png,MAC_Bench/Nature/Cover/Nature Climate Change/13_6.png,clip,13_6.txt,MAC_Bench/Nature/Cover/Nature Climate Change/10_12.png,MAC_Bench/Nature/Cover/Nature Climate Change/10_12.png,vitg,10_12.txt,MAC_Bench/Nature/Cover/Nature Climate Change/11_8.png,MAC_Bench/Nature/Cover/Nature Climate Change/11_8.png,ave_3,11_8.txt,train
Industrial & Engineering Chemistry Research,2024_6,Which of the following options best describe the cover story?,A novel machine learning framework that combines synthetic data generation by the CrystGAN model and an artificial neural network to predict the particle size distribution and yield in crystallization processes significantly reduces experimental effort and enables efficient data-driven process optimization. This cover art was generated with the help of OpenAI in ChatGPT and further edited by the authors.,A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_6.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_9.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_9.png,clip,2023_9.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_30.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_30.png,vitg,2024_30.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_28.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_28.png,vith,2024_28.txt,val
Trends in Ecology & Evolution,39_12,Which of the following options best describe the cover story?,"Plant roots show extraordinary diversity in form and function in
heterogeneous environments, as shown on the cover. There is a bi-dimensionality in
root traits, the root economics spectrum, and an orthogonal dimension describing how
nutrients are obtained. On pages 78−88, Yue Zhang, Deliang Kong and colleagues
propose that this bi-dimensionality arises from the cylindrical geometry of roots,
the
allometric relationship of root anatomical structures, and the independence between
root cell wall thickness and cell number. Cover credit: Beijing MyScimage Multimedia
Technology Center.",C,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/37_7.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/37_7.png,ave_1,37_7.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/35_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/35_1.png,vitg,35_1.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_12.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_12.png,groundtruth,39_12.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_1.png,clip,29_1.txt,test
NATURE REVIEWS GENETICS,25_1,Which of the following options best describe the cover story?,"Inspired by the Review on p829.
Cover design: Patrick Morgan",B,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_8.png,clip,25_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_1.png,groundtruth,25_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,train
Nature Machine Intelligence,6_3,Which of the following options best describe the cover story?,"Gathering knowledge on functionally invariant paths
When a neural network is optimized for more than one objective, improvement on a new task often results in worse performance on previously learned tasks. Raghavan et al. formulate this optimization problem in terms of differential geometry and follow paths that preserve previous solutions while searching for new ones.
See Raghavan et al.
Image: Vanitha Selvarajan. Cover design: Vanitha Selvarajan",C,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_11.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_11.png,ave_1,5_11.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_9.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_9.png,clip,3_9.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_3.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_3.png,groundtruth,6_3.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_8.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_8.png,vitg,5_8.txt,val
Nature Physics,21_1,Which of the following options best describe the cover story?,"Spinning swimmers
A particle rotating in a fluid generates vorticity around itself. Panyu Chen and co-workers show how the dynamics of a collection of such spinners suspended in a liquid can display flocking and three-dimensional active chirality.
See Chen et al.
Image: Hubert Gao, Panyu Chen, IrvineLab. Cover design: Laoise Mac Gabhann",A,MAC_Bench/Nature/Cover/Nature Physics/21_1.png,MAC_Bench/Nature/Cover/Nature Physics/21_1.png,groundtruth,21_1.txt,MAC_Bench/Nature/Cover/Nature Physics/16_8.png,MAC_Bench/Nature/Cover/Nature Physics/16_8.png,vitg,16_8.txt,MAC_Bench/Nature/Cover/Nature Physics/17_6.png,MAC_Bench/Nature/Cover/Nature Physics/17_6.png,clip,17_6.txt,MAC_Bench/Nature/Cover/Nature Physics/15_6.png,MAC_Bench/Nature/Cover/Nature Physics/15_6.png,vith,15_6.txt,train
Biomacromolecules,2024_7,Which of the following options best describe the cover story?,"The cover art design incorporates three key elements: metal ions, bone defect tissue, and hydrogel. The layout comprises an upper and lower structure. The upper part showcases multiple molecular formulas of hydrogel components and metal ions, while the lower part depicts a bone defect tissue filled with a metal ion-containing hybrid hydrogel, featuring the release of multiple metal ions from the hybrid hydrogel between bone trabeculae. The overall background is a dark blue with elements resembling a starry sky, evoking a sense of technology, artistry, and professionalism, closely aligning with the theme of the paper.",D,MAC_Bench/ACS/Cover/Biomacromolecules/2024_2.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2017_8.png,MAC_Bench/ACS/Cover/Biomacromolecules/2017_8.png,vitg,2017_8.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_10.png,vith,2021_10.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_7.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_7.png,groundtruth,2024_7.txt,train
Cell Reports,44_3,Which of the following options best describe the cover story?,"On the cover: A section of murine soleus and gastrocnemius muscles, distinguished
by their fiber composition and exhibiting varying levels of vulnerability throughout
the progression of amyotrophic lateral sclerosis (ALS). Spatial biology unveils opportunities
to explore the cellular and molecular networks underlying neuromuscular diseases.
Ruggieri et al. identify polyamines as key determinants of muscle fiber susceptibility in ALS, offering
insights into the mechanisms driving muscle atrophy in this disease. Image credit:
Luca Madaro and Veronica Ruggieri.",B,MAC_Bench/Cell/Cover/Cell Reports/24_5.png,MAC_Bench/Cell/Cover/Cell Reports/24_5.png,vitg,24_5.txt,MAC_Bench/Cell/Cover/Cell Reports/44_3.png,MAC_Bench/Cell/Cover/Cell Reports/44_3.png,groundtruth,44_3.txt,MAC_Bench/Cell/Cover/Cell Reports/22_12.png,MAC_Bench/Cell/Cover/Cell Reports/22_12.png,clip,22_12.txt,MAC_Bench/Cell/Cover/Cell Reports/23_6.png,MAC_Bench/Cell/Cover/Cell Reports/23_6.png,vith,23_6.txt,train
Trends in Chemistry,6_3,Which of the following options best describe the cover story?,"The ability to efficiently capture light energy and utilize this to convert
abundant small molecules, such as H2O, into high-value and much sought after
chemicals is still in its' infancy in catalysis, especially when compared to nature.
In their
review in this month's issue, Chen and colleagues discuss the promising progress made
when combining artificial solar energy conversion systems, such as semiconductors,
with efficient biocatalysts including enzymes and bacterial cells. This powerful
combination can provide remarkable activity, selectivity and efficiency in photocatalytic
conversion of small molecules, a step towards meet the demands of society.
Powerful hybrid systems for Image credit: C. Bo, J. Liu, X. Chen and L. Piao.",B,MAC_Bench/Cell/Cover/Trends in Chemistry/4_12.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_12.png,clip,4_12.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_3.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_3.png,groundtruth,6_3.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/5_12.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_12.png,vitg,5_12.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/2_1.png,MAC_Bench/Cell/Cover/Trends in Chemistry/2_1.png,ave_3,2_1.txt,train
Crystal Growth & Design,2024_7,Which of the following options best describe the cover story?,"Understanding CdTe thin-film growth is essential to enhancing its efficiency in optoelectronic and solar cell applications. Here, we investigated the growth dynamics of CdTe homoepitaxial films on Cd- and Te-terminated (111) surfaces at various temperatures using molecular dynamics and time-stamped force-bias Monte Carlo simulations with a machine-learning force field. The background image is generated using the OpenAI DALL-E program.",C,MAC_Bench/ACS/Cover/Crystal Growth & Design/2020_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2020_8.png,clip,2020_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_14.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_14.png,vitg,2024_14.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_7.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_21.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_21.png,ave_2,2024_21.txt,train
Cell Metabolism,36_1,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Metabolism, Tong et al. reveal that combining a serine and glycine-free (-SG) diet with PD-1 inhibitors enhances
antitumor immunity synergistically. The cover, inspired by Greek mythology, depicts
Athena battling a giant tumor cell. Wielding a shield empowered by the -SG diet, she
makes tumor eye (MHC-I) more prominent for CD8+ T cells, while her owl (PD-1 inhibitor)
targets PD-L1 to weaken tumor defenses, symbolizing synergistic therapy. Cover art
by Xuelei Ma and Yuhao Wei.",C,MAC_Bench/Cell/Cover/Cell Metabolism/28_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/28_5.png,ave_3,28_5.txt,MAC_Bench/Cell/Cover/Cell Metabolism/33_6.png,MAC_Bench/Cell/Cover/Cell Metabolism/33_6.png,vitg,33_6.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_1.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_1.png,groundtruth,36_1.txt,MAC_Bench/Cell/Cover/Cell Metabolism/35_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/35_5.png,clip,35_5.txt,train
Nature Photonics,18_6,Which of the following options best describe the cover story?,"Terahertz-driven electron guns
Artist’s impression of a waveguide-based terahertz-driven photogun that serves as a compact source of high-energy electrons. The design exploits a movable cathode tip and multiple cells to provide an acceleration gradient as high as ~3 GV/m. Using microjoule-level single-cycle terahertz pulses, electron beams with up to ~14 keV electron energy, 1% energy spread and ~0.015 mm mrad transverse emittance are possible.
See Ying et al.
Image: Jianwei Ying and Dongfang Zhang, Shanghai Jiao Tong University. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Photonics/12_7.png,MAC_Bench/Nature/Cover/Nature Photonics/12_7.png,vith,12_7.txt,MAC_Bench/Nature/Cover/Nature Photonics/16_7.png,MAC_Bench/Nature/Cover/Nature Photonics/16_7.png,clip,16_7.txt,MAC_Bench/Nature/Cover/Nature Photonics/17_9.png,MAC_Bench/Nature/Cover/Nature Photonics/17_9.png,ave_3,17_9.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_6.png,MAC_Bench/Nature/Cover/Nature Photonics/18_6.png,groundtruth,18_6.txt,train
Nature Reviews Physics,6_7,Which of the following options best describe the cover story?,"The cover of this issue illustrates the idea of controlling the orbital angular momentum of light. See Forbes et al.
Cover design: Susanne Harris.",C,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_7.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_7.png,clip,4_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_5.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_5.png,vith,5_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_7.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_7.png,groundtruth,6_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_8.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_8.png,vitg,3_8.txt,train
Nature Geoscience,17_10,Which of the following options best describe the cover story?,"Ancient human influence on wildfires
A shift towards more frequent, less intense fires in Australia began about 11,000 years ago due to management by indigenous societies, according to charcoal and polycyclic aromatic hydrocarbon records from cored lake sediments extending back 150,000 years. The image shows a raft-mounted hydraulic coring rig on Girraween Lagoon, northern Australia, looking over to Eucalypt savanna woodland. Middle right is the raft-mounted hydraulic coring rig used to take 18 metres of sediment from the bottom of the lake.
See Bird et al.
Image: Chris Wurster, James Cook University. Cover Design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/13_2.png,MAC_Bench/Nature/Cover/Nature Geoscience/13_2.png,ave_3,13_2.txt,MAC_Bench/Nature/Cover/Nature Geoscience/1_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_10.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_10.png,groundtruth,17_10.txt,MAC_Bench/Nature/Cover/Nature Geoscience/6_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_1.png,ave_2,6_1.txt,val
Nano Letters,2025_2,Which of the following options best describe the cover story?,"Tuning the mechanobiology of cells can enhance the interaction between nanoparticles and the cell membrane. As a key regulator of cell mechanics, the inhibition of yes-associated protein (YAP) may be leveraged to optimize cell",C,MAC_Bench/ACS/Cover/Nano Letters/2015_11.png,MAC_Bench/ACS/Cover/Nano Letters/2015_11.png,vitg,2015_11.txt,MAC_Bench/ACS/Cover/Nano Letters/2024_29.png,MAC_Bench/ACS/Cover/Nano Letters/2024_29.png,vith,2024_29.txt,MAC_Bench/ACS/Cover/Nano Letters/2025_2.png,MAC_Bench/ACS/Cover/Nano Letters/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Nano Letters/2015_2.png,MAC_Bench/ACS/Cover/Nano Letters/2015_2.png,clip,2015_2.txt,train
Accounts of Chemical Research,2024_19,Which of the following options best describe the cover story?,"The events occurring upon electron ionization span across 12 orders of magnitude in time, leading to the generation of numerous product ions detected by the mass spectrometer. Time-resolved measurements are helping scientists understand fragmentation patterns better and potentially impacting applications based on electron-initiated chemistry.",B,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_5.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_5.png,vith,2015_5.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_19.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_19.png,groundtruth,2024_19.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_3.png,clip,2019_3.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_2.png,vitg,2024_2.txt,train
Nature Plants,10_7,Which of the following options best describe the cover story?,"How to make a moss
Recent advances in DNA synthesis techniques have made possible the de novo synthesis of substantial genomes of organisms such as mycoplasma, bacteria and yeast. Synthesis of the genome of a multicellular organism remains out of reach, but the moss Physcomitrium patens could be the first.
See Yu et al. and Editorial
Image: Andreas Rullmann/Alamy Stock Photo. Cover design: Erin Dewalt",D,MAC_Bench/Nature/Cover/Nature Plants/10_8.png,MAC_Bench/Nature/Cover/Nature Plants/10_8.png,vitg,10_8.txt,MAC_Bench/Nature/Cover/Nature Plants/5_3.png,MAC_Bench/Nature/Cover/Nature Plants/5_3.png,clip,5_3.txt,MAC_Bench/Nature/Cover/Nature Plants/8_1.png,MAC_Bench/Nature/Cover/Nature Plants/8_1.png,vith,8_1.txt,MAC_Bench/Nature/Cover/Nature Plants/10_7.png,MAC_Bench/Nature/Cover/Nature Plants/10_7.png,groundtruth,10_7.txt,train
Nature Protocols,19_11,Which of the following options best describe the cover story?,"Terpene cyclization inside the resorcin[4]arene capsule
Hexameric capsules that self-assemble from resorcin[4]arene are shown in this rendered image. Luminous oxygen and hydrogen atoms highlight the hydrogen bond network holding the assemblies together. In the foreground, the capsule is open, revealing its content: a cyclized presilphiperfolanol molecule. See Cornu et al.
Image : Ivan Cornu, University of Basel. Cover design: S. Whitham.",B,MAC_Bench/Nature/Cover/Nature Protocols/17_2.png,MAC_Bench/Nature/Cover/Nature Protocols/17_2.png,clip,17_2.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_11.png,MAC_Bench/Nature/Cover/Nature Protocols/19_11.png,groundtruth,19_11.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_6.png,MAC_Bench/Nature/Cover/Nature Protocols/19_6.png,ave_2,19_6.txt,MAC_Bench/Nature/Cover/Nature Protocols/20_1.png,MAC_Bench/Nature/Cover/Nature Protocols/20_1.png,ave_3,20_1.txt,val
Trends in Plant Science,29_6,Which of the following options best describe the cover story?,"To germinate in nature, orchid seeds strictly rely on seed germination-promoting
orchid mycorrhizal fungi (sgOMF) for provision of carbon nutrients. The
pathway for delivering these nutrients, however, remains elusive. Da-Ke Zhao, Zong-Min
Mou, and Yong-Ling Ruan present a model that explains how sugar is transported from
sgOMF to orchid embryonic cells to fuel germination. The proposed model serves as
a
launch pad for further research to better understand and improve orchid seed germination
and conservation. Image credit (public domain, National Gallery of Art): Painting
by Martin
Johnson Heade, Cattleya Orchid and Three Hummingbirds, 1871 (detail).",B,MAC_Bench/Cell/Cover/Trends in Plant Science/29_3.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_3.png,vitg,29_3.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_6.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_6.png,groundtruth,29_6.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/25_5.png,MAC_Bench/Cell/Cover/Trends in Plant Science/25_5.png,clip,25_5.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_12.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_12.png,vith,29_12.txt,train
Lab Animal,53_1,Which of the following options best describe the cover story?,"Digging deeper into the marble burying task
The marble burying task (MBT) is widely used to measure anxiety-like behavior in rodent models, but it is not typically video-recorded. In our first Brief Communication, Burgett et al. show that using a single photo at the end of the task might not be a reliable indicator of rodent engagement with marbles. The authors suggest that video analysis might provide a more accurate representation of the rich set of behaviors displayed in the MBT.
See Burgett et al.
Cover image: Marina Spence. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Lab Animal/52_7.png,MAC_Bench/Nature/Cover/Lab Animal/52_7.png,vith,52_7.txt,MAC_Bench/Nature/Cover/Lab Animal/49_4.png,MAC_Bench/Nature/Cover/Lab Animal/49_4.png,ave_1,49_4.txt,MAC_Bench/Nature/Cover/Lab Animal/53_8.png,MAC_Bench/Nature/Cover/Lab Animal/53_8.png,clip,53_8.txt,MAC_Bench/Nature/Cover/Lab Animal/53_1.png,MAC_Bench/Nature/Cover/Lab Animal/53_1.png,groundtruth,53_1.txt,test
Nature Protocols,19_5,Which of the following options best describe the cover story?,"Illuminating the mechanisms of small-molecule-induced protein proximity and degradation
Small-molecule-induced ternary complexes of NanoLuciferase (NLuc)-fused E3 ligase and a HaloTag-fused neosubstrate are shown. The induced proximity between the two proteins leads to bioluminescence resonance energy transfer (BRET) between the blue luminescent NLuc and the pink BRET acceptor. The formation of these ternary complexes leads to the ubiquitination and subsequent degradation of the neosubstrates by the proteasome as shown in the background.
Image : Martin Schwalm, Goethe University Frankfurt. Cover design: S. Whitham",B,MAC_Bench/Nature/Cover/Nature Protocols/19_6.png,MAC_Bench/Nature/Cover/Nature Protocols/19_6.png,clip,19_6.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_5.png,MAC_Bench/Nature/Cover/Nature Protocols/19_5.png,groundtruth,19_5.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_3.png,MAC_Bench/Nature/Cover/Nature Protocols/15_3.png,ave_2,15_3.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_2.png,MAC_Bench/Nature/Cover/Nature Protocols/15_2.png,vitg,15_2.txt,test
Cell Genomics,4_11,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Xu et al. present their findings that Epstein-Barr virus (EBV)-host genetic interaction predisposes
susceptibility to nasopharyngeal carcinoma (NPC). This EBV-related cancer, though
rare in most parts of the world, is highly endemic in southern China. Illustrated
on the cover, the red virus and double-stranded DNA symbols capture the strong interaction
between the high-risk subtype of EBV and susceptible HLA alleles. This interaction
is the major determinant of NPC risk among southern Chinese populations. The cover
art was created by the artist Rui Xie.",A,MAC_Bench/Cell/Cover/Cell Genomics/4_11.png,MAC_Bench/Cell/Cover/Cell Genomics/4_11.png,groundtruth,4_11.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_11.png,MAC_Bench/Cell/Cover/Cell Genomics/2_11.png,vitg,2_11.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_1.png,MAC_Bench/Cell/Cover/Cell Genomics/2_1.png,ave_1,2_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,clip,4_7.txt,train
Journal of Chemical Theory and Computation,2025_1,Which of the following options best describe the cover story?,s-molecular dynamics simulations and umbrella sampling simulations allow the rationalization of New Delhi metallo-β-lactamase 1 enzyme inhibition by ebselen and ebsulfur to contrast antibiotic resistance. The role of chalcogen,C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_21.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_21.png,clip,2024_21.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,vith,2021_12.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2025_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2018_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2018_12.png,vitg,2018_12.txt,train
ACS Macro Letters,2024_6,Which of the following options best describe the cover story?,"Blue butterflies (reagents) try to access to the flowers (catalytic sites) either arranged randomly on the surface of the left tree (dendrimer) or precisely on the surface of the right tree (dendrimer). After reaching the flowers, blue butterflies are transformed to orange butterflies (products).",A,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_6.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_9.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2020_9.png,ave_2,2020_9.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2015_3.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2015_3.png,vitg,2015_3.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2022_11.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2022_11.png,clip,2022_11.txt,train
ACS Applied Polymer Materials,2024_14,Which of the following options best describe the cover story?,"Advanced microscopy techniques in 3D views reveal the periodic assembly of PHBV crystals. The study uncovers highly-ordered interior architectures with grating-like periodicity, which mimics the nature's assembled photonic crystals. The orderly grating assembly is tested to lead to iridescence",B,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_5.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_5.png,vitg,2022_5.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_14.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_23.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_23.png,ave_3,2024_23.txt,test
Structure,32_1,Which of the following options best describe the cover story?,"On the cover: The illustration shows an artistic representation of chains of Streptococcus pyogenes bacteria, highlighting the inner membrane-embedded FtsABCD system responsible for
the capture of siderophores. Several hydroxamate siderophores with different structures
are shown surrounding the transporter in the periplasmic space. This illustration
symbolizes the ability of the membrane-anchored periplasmic binding protein, FtsB,
to recognize ligands with different structures as demonstrated in this issue by Fernández-Pérez et al. The conserved binding pocket of FtsB is depicted in red and reproduces the capture
of a molecule of Ferrichrome. Illustration by Jorge Fernández Pérez.",C,MAC_Bench/Cell/Cover/Structure/31_4.png,MAC_Bench/Cell/Cover/Structure/31_4.png,vitg,31_4.txt,MAC_Bench/Cell/Cover/Structure/22_2.png,MAC_Bench/Cell/Cover/Structure/22_2.png,clip,22_2.txt,MAC_Bench/Cell/Cover/Structure/32_1.png,MAC_Bench/Cell/Cover/Structure/32_1.png,groundtruth,32_1.txt,MAC_Bench/Cell/Cover/Structure/32_11.png,MAC_Bench/Cell/Cover/Structure/32_11.png,vith,32_11.txt,train
Nature Reviews Psychology,3_2,Which of the following options best describe the cover story?,"In this Perspective, Helmich et al. question the clinical utility of early warning signals and discuss alternative avenues for early change prediction.
Cover design: David Johnston",B,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_9.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_2.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_2.png,groundtruth,3_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,ave_1,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_4.png,clip,2_4.txt,train
Nature Reviews Materials,9_9,Which of the following options best describe the cover story?,"Crystallization of soft materials often follows pathways not envisioned in classical theories of crystallization, instead passing through disordered, amorphous, or dense liquid precursors. The recent emergence of techniques to probe these pathways with minimal damage has led to a growing knowledge about these pathways. The image illustrates crystallization via a dense liquid precursor as the free energy of the system decreases, as well as the in-situ observation of this process. See Du J.S. et al
Cover image: Cortland Johnson. Cover design: David Johnston",C,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_3.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_3.png,vitg,2_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_2.png,vith,3_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,groundtruth,9_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_8.png,clip,5_8.txt,train
Cell Chemical Biology,31_12,Which of the following options best describe the cover story?,"On the cover: Hazawa et al. demonstrate that the formation of biomolecular condensate droplets (transparent bubble)
is promoted by protein-protein interactions between NUP153 (blue protein within bubble)
and the coactivator BRD4 (green protein within bubble). These interactions bring phase-separated
super-enhancer-containing DNA close to mRNA exporters like TPR (green and yellow pores),
promoting mRNA export (purple spirals) and TP63 oncogene expression. Image courtesy
of the authors.",C,MAC_Bench/Cell/Cover/Cell Chemical Biology/16_2.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/16_2.png,vitg,16_2.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_6.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_6.png,vith,18_6.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_12.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_12.png,groundtruth,31_12.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_5.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_5.png,clip,19_5.txt,train
Nature Electronics,7_2,Which of the following options best describe the cover story?,"Soft electronics in 3D
Soft vias for connecting circuit layers can be created by using programmed photocuring to direct the assembly of liquid metal droplets. The photograph on the cover shows a multilayer soft circuit fabricated with the approach that can be used to sense magnetic fields and display the result by illuminating light-emitting diodes.
See Ho et al. and News & Views by Babatain
Image: Dong Hae Ho and Michael D. Bartlett, Virginia Tech. Cover design: Lauren Heslop",D,MAC_Bench/Nature/Cover/Nature Electronics/2_12.png,MAC_Bench/Nature/Cover/Nature Electronics/2_12.png,vith,2_12.txt,MAC_Bench/Nature/Cover/Nature Electronics/5_1.png,MAC_Bench/Nature/Cover/Nature Electronics/5_1.png,vitg,5_1.txt,MAC_Bench/Nature/Cover/Nature Electronics/6_4.png,MAC_Bench/Nature/Cover/Nature Electronics/6_4.png,clip,6_4.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_2.png,MAC_Bench/Nature/Cover/Nature Electronics/7_2.png,groundtruth,7_2.txt,train
BDJ In Practice,37_6,Which of the following options best describe the cover story?,"In this issue...
July's BDJ In Practice takes a deep dive into the state of the debate surrounding global oral health and sugar - have we been here before?
Cover illustration by Tim Marrs",A,MAC_Bench/Nature/Cover/BDJ In Practice/37_6.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_6.png,groundtruth,37_6.txt,MAC_Bench/Nature/Cover/BDJ In Practice/33_12.png,MAC_Bench/Nature/Cover/BDJ In Practice/33_12.png,clip,33_12.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,vith,36_1.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,vitg,35_8.txt,train
Trends in Immunology,45_7,Which of the following options best describe the cover story?,"The effect of COVID-19 on the high number of immunocompromised
people living with HIV-1 (PLWH), particularly in Africa, remains a global and significant
concern. On pages 511–522, Moore and colleagues discuss antibody responses to
SARS-CoV-2 infection and vaccination in PLWH vs. non-infected individuals. They also
provide insight into the effects of persistent SARS-CoV2 infection in PLWH, including
intra-host diversity, viral shedding, and variant evolution. The illustration depicts
the Fab
of a cross-reactive neutralizing antibody targeting the CD4 binding site of HIV-1
gp120.
Image credit: Mehau Kulyk, SPL/GettyImages.",D,MAC_Bench/Cell/Cover/Trends in Immunology/44_11.png,MAC_Bench/Cell/Cover/Trends in Immunology/44_11.png,ave_3,44_11.txt,MAC_Bench/Cell/Cover/Trends in Immunology/41_1.png,MAC_Bench/Cell/Cover/Trends in Immunology/41_1.png,clip,41_1.txt,MAC_Bench/Cell/Cover/Trends in Immunology/40_11.png,MAC_Bench/Cell/Cover/Trends in Immunology/40_11.png,ave_2,40_11.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_7.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_7.png,groundtruth,45_7.txt,test
ACS Sustainable Resource Management,2024_10,Which of the following options best describe the cover story?,"On the journal cover a degraded perovskite photovoltaic device is depicted in the back. The recent work of Bogachuk et al. demonstrates an effective end-of-life strategy to reuse part of the device and remanufacture such solar cells and modules via a novel thermally assisted mechanochemical approach, which strongly reduces their carbon footprint.",C,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,vith,2024_12.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,vitg,2024_2.txt,val
Nature Cities,1_3,Which of the following options best describe the cover story?,"Quantifying 15-minute cities
Quantifying the potential to achieve 15-minute cities, Bruno et al. measure the proximity time to access essential services and amenities across global cities. The 3D maps of Rome, Fortaleza, Nairobi, Mumbai, Hanoi and Bogotá show population density as the height of the bars, and blue, yellow and red as high, medium and low levels of accessibility.
See Bruno et al.
Image: Matteo Bruno, Sony Computer Science Laboratories - Rome. Hygor Piaget Monteiro Melo, Sony Computer Science Laboratories – Rome. Cover design: Lauren Heslop.",B,MAC_Bench/Nature/Cover/Nature Cities/1_10.png,MAC_Bench/Nature/Cover/Nature Cities/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,groundtruth,1_3.txt,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,vith,1_2.txt,MAC_Bench/Nature/Cover/Nature Cities/1_8.png,MAC_Bench/Nature/Cover/Nature Cities/1_8.png,vitg,1_8.txt,train
Science Signaling,2007_381,Which of the following options best describe the cover story?,"COVER This week features an Editorial Guide on new approaches to cancer therapy, as well as two Perspectives and a Review. The image depicts colon cancer progression. [Image: Adapted from an image from the National Cancer Institute; Terese Winslow (copyright 2005), U.S. Govt. has certain rights]",C,MAC_Bench/Science/Cover/Science Signaling/3_117.png,MAC_Bench/Science/Cover/Science Signaling/3_117.png,vith,3_117.txt,MAC_Bench/Science/Cover/Science Signaling/1_39.png,MAC_Bench/Science/Cover/Science Signaling/1_39.png,vitg,1_39.txt,MAC_Bench/Science/Cover/Science Signaling/2007_381.png,MAC_Bench/Science/Cover/Science Signaling/2007_381.png,groundtruth,2007_381.txt,MAC_Bench/Science/Cover/Science Signaling/6_287.png,MAC_Bench/Science/Cover/Science Signaling/6_287.png,clip,6_287.txt,train
Trends in Pharmacological Sciences,45_4,Which of the following options best describe the cover story?,"Autoantibody binding is central to autoimmune diseases and broadly
linked to cancer, infections, and behavioural disorders. The lack of understanding
of disease-specific epitopes — crucial for pathology and diagnosis — has led to
misclassification of autoimmune neurological diseases. In this issue, Ivan Talucci
and
Hans Michael Maric propose the utilization of newly available technology to decode
epitope landscapes in neurological diseases to unlock new avenues for patient
diagnosis and treatment. They highlight the relevance of B and T cell epitopes for
identifying biomarkers in high-risk patients and discuss how synthetic and cellularsurface
display technologies can improve diagnosis and enable treatments. The
cover image depicts a combination of epitope landscapes decoded from microarray
chip-based experiments. Cover designed by Ivan Talucci and Hans Michael Maric
using Adobe illustrator and Photoshop.",D,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,clip,34_8.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/37_1.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/37_1.png,vith,37_1.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/43_5.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/43_5.png,ave_1,43_5.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_4.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_4.png,groundtruth,45_4.txt,train
ACS Photonics,2024_3,Which of the following options best describe the cover story?,"A dual-comb laser measures the depth-dependent dynamics within a multi-layered turbid medium, thereby offering the potential to measure the blood flow in different layers.",B,MAC_Bench/ACS/Cover/ACS Photonics/2016_7.png,MAC_Bench/ACS/Cover/ACS Photonics/2016_7.png,vitg,2016_7.txt,MAC_Bench/ACS/Cover/ACS Photonics/2024_3.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Photonics/2022_4.png,MAC_Bench/ACS/Cover/ACS Photonics/2022_4.png,clip,2022_4.txt,MAC_Bench/ACS/Cover/ACS Photonics/2022_12.png,MAC_Bench/ACS/Cover/ACS Photonics/2022_12.png,vith,2022_12.txt,val
Nature Protocols,19_6,Which of the following options best describe the cover story?,"Classification of T cell behavior
Tracking the trajectory of engineered T cells targeted against patient-derived cancer organoids reveals different patterns of behavior. Cancer organoids are displayed in white, and T cells with different behavioral profiles are displayed in different colors. Tracks from live confocal imaging are loosely traced by hand to portray the plasticity of T cell movement. See Alieva et al.
Image: Mario Barrera Román, Maria Alieva, Florijn Dekkers, The Dream3DLAB, Princess Máxima Center. Cover design: S. Whitham",C,MAC_Bench/Nature/Cover/Nature Protocols/17_11.png,MAC_Bench/Nature/Cover/Nature Protocols/17_11.png,vith,17_11.txt,MAC_Bench/Nature/Cover/Nature Protocols/13_11.png,MAC_Bench/Nature/Cover/Nature Protocols/13_11.png,vitg,13_11.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_6.png,MAC_Bench/Nature/Cover/Nature Protocols/19_6.png,groundtruth,19_6.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_6.png,MAC_Bench/Nature/Cover/Nature Protocols/15_6.png,clip,15_6.txt,train
Nature Sustainability,7_1,Which of the following options best describe the cover story?,"Cropland abandonment and biodiversity
Amidst continued cropland expansion in recent decades, substantial amounts of cropland area have been abandoned owing to various socioeconomic, demographic and technological factors. Crawford and colleagues examine how such cropland abandonment affects bird and mammal species at the landscape scale across four continents.
See Crawford et al.
Image and cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Sustainability/3_12.png,MAC_Bench/Nature/Cover/Nature Sustainability/3_12.png,vitg,3_12.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_1.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_1.png,groundtruth,7_1.txt,MAC_Bench/Nature/Cover/Nature Sustainability/5_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/5_4.png,clip,5_4.txt,MAC_Bench/Nature/Cover/Nature Sustainability/3_1.png,MAC_Bench/Nature/Cover/Nature Sustainability/3_1.png,ave_2,3_1.txt,train
Nature Electronics,7_3,Which of the following options best describe the cover story?,"Two-dimensional devices stack up
Graphene chemisensors and molybdenum disulfide memtransistors can be vertically stacked using a monolithic integration process to create near-sensor computing chips. The false-colour scanning electron microscopy image on the cover shows a two-tier cell containing two graphene chemitransistors located above two molybdenum disulfide memtransistors.
See Ghosh et al. and News & Views by Han et al.
Image: Saptarshi Das, Subir Ghosh, The Pennsylvania State University. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Electronics/4_7.png,MAC_Bench/Nature/Cover/Nature Electronics/4_7.png,vitg,4_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_3.png,MAC_Bench/Nature/Cover/Nature Electronics/7_3.png,groundtruth,7_3.txt,MAC_Bench/Nature/Cover/Nature Electronics/4_3.png,MAC_Bench/Nature/Cover/Nature Electronics/4_3.png,vith,4_3.txt,MAC_Bench/Nature/Cover/Nature Electronics/3_4.png,MAC_Bench/Nature/Cover/Nature Electronics/3_4.png,clip,3_4.txt,train
Trends in Pharmacological Sciences,45_13,Which of the following options best describe the cover story?,"Many aspects of cell homeostasis and integrity are maintained by the nucleotide-binding
oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome.
The NLRP3 oligomeric protein complex assembles in response to exogenous and endogenous
danger signals. This inflammasome has also been implicated in the pathogenesis of
a wide range of disease conditions, particularly chronic inflammatory diseases. As
NLRP3 modulates autophagy, which is also a key regulator of inflammasome activity,
excessive inflammation may be controlled by targeting these intersecting pathways.
In a Review article of this issue, Bonam, Mastrippolito et al. discuss the potential of strategies that target the lysosomal autophagy–NLRP3 inflammasome
intersecting pathways in the context of autoimmune and metabolic diseases. Image credit:
Grace Maina via Getty Images Plus.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_2.png,vitg,42_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/31_5.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/31_5.png,clip,31_5.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_13.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_13.png,groundtruth,45_13.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_9.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_9.png,vith,42_9.txt,train
Environment & Health,2024_5,Which of the following options best describe the cover story?,"The composition of fine particulate matter (PM2.5) is intricate, and its various components have diverse effects on human health. Delving into the impact of PM2.5 components from different sources on cardiopulmonary health contributes to safeguarding public health.",C,MAC_Bench/ACS/Cover/Environment & Health/2023_2.png,MAC_Bench/ACS/Cover/Environment & Health/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2025_2.png,MAC_Bench/ACS/Cover/Environment & Health/2025_2.png,ave_1,2025_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_5.png,MAC_Bench/ACS/Cover/Environment & Health/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_8.png,MAC_Bench/ACS/Cover/Environment & Health/2024_8.png,clip,2024_8.txt,train
Molecular Pharmaceutics,2024_11,Which of the following options best describe the cover story?,"More is not always better, and finding the balance is crucial. Van Weijsten and Venrooij et al. showed that the orientation and valency of a synthetic autoantigen mimic has a great effect on the binding properties to cell-bound receptors and the competing free-floating antibodies.",B,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_3.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_3.png,clip,2022_3.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_11.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_2.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_2.png,ave_1,2020_2.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_12.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_12.png,vitg,2020_12.txt,test
Accounts of Materials Research,2024_8,Which of the following options best describe the cover story?,Self-powered medical implants serve as a promising,D,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_11.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_11.png,vith,2023_11.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_10.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_10.png,vitg,2023_10.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_3.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_3.png,clip,2022_3.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_8.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_8.png,groundtruth,2024_8.txt,train
Nature Reviews Cardiology,21_4,Which of the following options best describe the cover story?,"Stress and cardiovascular disease, inspired by the Review on p603.
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_8.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_8.png,vitg,19_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_4.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_4.png,groundtruth,21_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_7.png,clip,18_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_9.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_9.png,ave_2,18_9.txt,train
ACS Physical Chemistry Au,2025_1,Which of the following options best describe the cover story?,A water channel is formed across the light-harvesting complex of a diatom in response to high light exposure. The channel,B,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_3.png,ave_3,2022_3.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2021_1.png,vitg,2021_1.txt,train
Molecular Plant,18_1,Which of the following options best describe the cover story?,"On the cover: In this issue, Lei et al. explore the regulatory role of the long non-coding RNA
ALEX1 in enhancing the resistance of rice to bacterial infections through its interaction
with ARF3. Under normal conditions, ALEX1 is expressed at low levels, allowing ARF3 to aggregate into solid-like condensates,
representing an inactive or “non-functional” phase state. However, upon pathogen infection,
ALEX1 expression is upregulated, and it binds directly to the MR domain of ARF3, facilitating
its dimerization and preventing condensate formation. This transition maintains an
active ARF3 pool, which represses the transcription of JAZ13 and activates the jasmonic acid (JA) pathway, thereby enhancing plant defense. The
cover image depicts the dynamic interplay between ALEX1 and ARF3 in modulating rice immunity. ALEX1 is portrayed as a bow, symbolizing its role in activating ARF3, represented by arrows.
The quiver on the angel's back, filled with blue arrows, signifies ARF3 in its non-functional
condensate state. This visual metaphor highlights how ALEX1 enables ARF3 transition to a functional state, orchestrating plant defense responses
against bacterial pathogens. Image by Meng-Qi Lei, Yang Yu and Yue-Qin Chen.",D,MAC_Bench/Cell/Cover/Molecular Plant/15_9.png,MAC_Bench/Cell/Cover/Molecular Plant/15_9.png,vith,15_9.txt,MAC_Bench/Cell/Cover/Molecular Plant/16_5.png,MAC_Bench/Cell/Cover/Molecular Plant/16_5.png,clip,16_5.txt,MAC_Bench/Cell/Cover/Molecular Plant/14_3.png,MAC_Bench/Cell/Cover/Molecular Plant/14_3.png,vitg,14_3.txt,MAC_Bench/Cell/Cover/Molecular Plant/18_1.png,MAC_Bench/Cell/Cover/Molecular Plant/18_1.png,groundtruth,18_1.txt,train
ACS Earth and Space Chemistry,2024_8,Which of the following options best describe the cover story?,Density functional theory calculations are used to probe the possibility of the formation of benzene from acetylene precursors on the surface of olivine dust particles.,B,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_7.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_7.png,ave_3,2024_7.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_8.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_1.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_1.png,clip,2024_1.txt,train
Environment & Health,2025_1,Which of the following options best describe the cover story?,The use of ibuprofen could mitigate the association of long-term exposure to PM2.5 and its components with all-cause and cause-specific mortality.,B,MAC_Bench/ACS/Cover/Environment & Health/2023_2.png,MAC_Bench/ACS/Cover/Environment & Health/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2025_1.png,MAC_Bench/ACS/Cover/Environment & Health/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_5.png,MAC_Bench/ACS/Cover/Environment & Health/2024_5.png,ave_1,2024_5.txt,train
Molecular Plant,17_9,Which of the following options best describe the cover story?,"On the cover: The cover image illustrates a story showing that tomato domestication and improvement
reduce drought tolerance. Wild and cultivated tomato may encounter various levels
of drought stress during their growth and reproduction. In the process of tomato domestication
and improvement, fruit weight and size are the key traits that have underwent artificial
selection. However, this process has reduced the rich genetic diversity of wild tomatoes,
leading to negative selection of many kinds of metabolites such as phenolamides. In
this issue, Cao et al. found that the levels of phenolamides are primarily controlled
by two biosynthetic gene clusters, BGC7 and BGC11, and their regulator of the transcription
factor SlMYB13, all of which have been subjected to artificial negative selection
that has caused reduced drought resistance in cultivated tomatoes. Image by: Shouchuang
Wang, Peng Cao and Jun Yang with the assistance of DALL·E (https://openai.com).",A,MAC_Bench/Cell/Cover/Molecular Plant/17_9.png,MAC_Bench/Cell/Cover/Molecular Plant/17_9.png,groundtruth,17_9.txt,MAC_Bench/Cell/Cover/Molecular Plant/13_14.png,MAC_Bench/Cell/Cover/Molecular Plant/13_14.png,clip,13_14.txt,MAC_Bench/Cell/Cover/Molecular Plant/13_7.png,MAC_Bench/Cell/Cover/Molecular Plant/13_7.png,ave_1,13_7.txt,MAC_Bench/Cell/Cover/Molecular Plant/13_6.png,MAC_Bench/Cell/Cover/Molecular Plant/13_6.png,ave_3,13_6.txt,train
Science Robotics,9_86,Which of the following options best describe the cover story?,ONLINE COVER Programmable Matter—Lattice structures can be self-assembled and reconfigured autonomously using robots. Gregg et al. report on a self-reprogrammable system made of lightweight and high-strength carbon fiber–reinforced composite unit cells that can be assembled by transport and fastening robots. The robots work collaboratively with the aid of a path-planning algorithm to build lattice structures of desired geometry and to form mechanical metamaterials at scale. This month’s cover is an image of the robots working collaboratively to build the metamaterial lattice structure. Credit: NASA/Brandon Torres,B,MAC_Bench/Science/Cover/Science Robotics/8_76.png,MAC_Bench/Science/Cover/Science Robotics/8_76.png,clip,8_76.txt,MAC_Bench/Science/Cover/Science Robotics/9_86.png,MAC_Bench/Science/Cover/Science Robotics/9_86.png,groundtruth,9_86.txt,MAC_Bench/Science/Cover/Science Robotics/9_93.png,MAC_Bench/Science/Cover/Science Robotics/9_93.png,vitg,9_93.txt,MAC_Bench/Science/Cover/Science Robotics/3_15.png,MAC_Bench/Science/Cover/Science Robotics/3_15.png,vith,3_15.txt,train
Nature Chemical Engineering,1_6,Which of the following options best describe the cover story?,"Artificial transmembrane transport
Building artificial cells that mimic the functions of biological cells represents a fundamental challenge. A major bottleneck is the transport of substances across the artificial cell membrane. Now, Nan-Nan Deng and colleagues demonstrate an endocytosis-/exocytosis-like transmembrane transport in a liposome-based system. By utilizing interfacial energy, liposomes can reversibly engulf and excrete oil microdroplets, which can subsequently be exploited as reconfigurable oil-based channels for molecular transport. The cover illustrates the shuttling process of ions and DNA across the oil-based channels.
See Tian et al. and Parikh
Image: Nan-Nan Deng, Shanghai Jiao Tong University. Cover design: Thomas Phillips.",C,MAC_Bench/Nature/Cover/Nature Chemical Engineering/2_1.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/2_1.png,vith,2_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,groundtruth,1_6.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,vitg,1_5.txt,test
ACS Engineering Au,2024_6,Which of the following options best describe the cover story?,"Driven by readily available renewable energy, the direct electrification of energy-intensive chemical processes via Joule heating provides a promising route for decarbonization, shows potential to overcome heat transfer limitations, and enables process intensification by the design of compact reactors.",D,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_2.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_2.png,clip,2021_2.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_2.png,ave_1,2024_2.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_6.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_6.png,groundtruth,2024_6.txt,train
ACS Sustainable Resource Management,2024_2,Which of the following options best describe the cover story?,A simple process using membrane distillation by gas–liquid exchange successfully removed tritiated water (HTO) from HTO-containing water. The gas–liquid exchange occurred in each glass fiber filter through the reflux behavior of HTO vapor. The ratio of HTO in water was reduced to about 12 ± 0.3% from that of the original HTO-containing water.,B,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,vitg,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,vith,2024_10.txt,train
ACS Nano,2025_2,Which of the following options best describe the cover story?,"sequential-logic-in-memory (S-LiM) concept using a single van der Waals ferroelectric field-effect transistor (vdW FeFET) capable of performing sequential logic operations in two non-volatile states. This compact and energy-efficient design offers substantial advantages for edge computing, positioning the vdW FeFET as a promising candidate for next-generation edge computing devices that require high performance and versatility in resource-constrained environments. View the article.",C,MAC_Bench/ACS/Cover/ACS Nano/2021_8.png,MAC_Bench/ACS/Cover/ACS Nano/2021_8.png,ave_1,2021_8.txt,MAC_Bench/ACS/Cover/ACS Nano/2024_19.png,MAC_Bench/ACS/Cover/ACS Nano/2024_19.png,clip,2024_19.txt,MAC_Bench/ACS/Cover/ACS Nano/2025_2.png,MAC_Bench/ACS/Cover/ACS Nano/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Nano/2017_6.png,MAC_Bench/ACS/Cover/ACS Nano/2017_6.png,ave_2,2017_6.txt,train
Journal of Chemical Education,2021_1,Which of the following options best describe the cover story?,"In ""Using Sodium Hydrogen Carbonate to Teach Chemical Concepts of Thermodynamics"" (DOI: 10.1021/acs.jchemed.1c00680), Daisuke Kajiya demonstrates the use of aqueous sodium hydrogen carbonate in simple experiments with common equipment to help strengthen students' understanding of thermodynamics. Topics covered include the ideal gas law, the van't Hoff equation, Gibbs energy, pH change, chemical equilibrium, and pattern formation (as featured on the cover). These activities were successfully used with first-year and second-year undergraduate nonscience majors to study various basic principles of chemistry.",D,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_2.png,vith,2016_2.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2015_9.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2015_9.png,clip,2015_9.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2019_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2019_5.png,ave_1,2019_5.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_1.png,groundtruth,2021_1.txt,train
Current Biology,34_18,Which of the following options best describe the cover story?,"On the cover: Dedicated stress response pathways help cells adjust to environmental
and cellular stresses. In this issue, Chen and McDonald show that an intrinsic endoplasmic reticulum (ER) stress response helps Drosophila border cells migrate collectively in the ovary during oogenesis. This image shows
a dispersed ovary with strings of progressively developing egg chambers. The cell
nuclei are labeled in gold and the cell membranes and the ovary's muscle sheath are
labeled in magenta. Inside each egg chamber, border cells, labeled in blue, migrate
during mid-oogenesis to reach the oocyte, the large brown cell. Image by Yujun Chen.",A,MAC_Bench/Cell/Cover/Current Biology/34_18.png,MAC_Bench/Cell/Cover/Current Biology/34_18.png,groundtruth,34_18.txt,MAC_Bench/Cell/Cover/Current Biology/23_20.png,MAC_Bench/Cell/Cover/Current Biology/23_20.png,clip,23_20.txt,MAC_Bench/Cell/Cover/Current Biology/27_16.png,MAC_Bench/Cell/Cover/Current Biology/27_16.png,vitg,27_16.txt,MAC_Bench/Cell/Cover/Current Biology/23_1.png,MAC_Bench/Cell/Cover/Current Biology/23_1.png,vith,23_1.txt,train
Current Biology,34_4,Which of the following options best describe the cover story?,"On the cover: A close-up view of the head of a tokay gecko (Gekko gecko). In this issue, Han and Carr demonstrate an additional auditory pathway that does not involve the tympanic middle
ear shown in this image. The saccule, an inner ear organ typically associated with
balance, is crucial for detecting substrate-borne vibrations in geckos and possibly
other lizards and snakes. This auditory role of the saccule is an ancestral feature
found in fish and amphibians and is likely preserved in amniotes via the lepidosaurian
lineage. Photograph © Duncan Leitch, used with permission.",C,MAC_Bench/Cell/Cover/Current Biology/32_2.png,MAC_Bench/Cell/Cover/Current Biology/32_2.png,clip,32_2.txt,MAC_Bench/Cell/Cover/Current Biology/34_8.png,MAC_Bench/Cell/Cover/Current Biology/34_8.png,vith,34_8.txt,MAC_Bench/Cell/Cover/Current Biology/34_4.png,MAC_Bench/Cell/Cover/Current Biology/34_4.png,groundtruth,34_4.txt,MAC_Bench/Cell/Cover/Current Biology/20_14.png,MAC_Bench/Cell/Cover/Current Biology/20_14.png,ave_3,20_14.txt,train
ACS Applied Optical Materials,2024_10,Which of the following options best describe the cover story?,A novel inorganic–organic framework composed of layered clay nanosheets bridged by a pillar-shaped multicationic double-decker porphyrin metal complex having long alkyl sidechains was synthesized through a cation exchange reaction and applied for an efficient adsorbent for various anionic organic dyes.,C,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_9.png,ave_2,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_1.png,vith,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_1.png,clip,2023_1.txt,test
Nature Reviews Nephrology,20_3,Which of the following options best describe the cover story?,"Podocyte-targeted therapies, inspired by the Review on p643.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_7.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_7.png,ave_1,20_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,vitg,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/21_2.png,clip,21_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_3.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_3.png,groundtruth,20_3.txt,train
Current Biology,34_5,Which of the following options best describe the cover story?,"On the cover: Common pond skaters (Gerris lacustris) on the surface of a river in the Lake District, UK. These predatory insects exploit
the high surface tension of water to skate across the water's surface, a process facilitated
by their long, hydrophobic legs and the distribution of their weight over a large
surface area, providing a clear example of how physical principles impact biology.
Our special issue on the collaboration between physics and biology brings together
reviews, essays, primers, and other formats to showcase the various ways in which
physical concepts and approaches have enhanced our understanding of the living world.
Photo: Ashley Cooper/Getty Images.",B,MAC_Bench/Cell/Cover/Current Biology/28_19.png,MAC_Bench/Cell/Cover/Current Biology/28_19.png,vith,28_19.txt,MAC_Bench/Cell/Cover/Current Biology/34_5.png,MAC_Bench/Cell/Cover/Current Biology/34_5.png,groundtruth,34_5.txt,MAC_Bench/Cell/Cover/Current Biology/25_20.png,MAC_Bench/Cell/Cover/Current Biology/25_20.png,vitg,25_20.txt,MAC_Bench/Cell/Cover/Current Biology/34_19.png,MAC_Bench/Cell/Cover/Current Biology/34_19.png,clip,34_19.txt,train
Nature Machine Intelligence,6_6,Which of the following options best describe the cover story?,"Pre-trained knowledge for lifelike movements
Utilizing pre-training holds great promise in legged robotics to produce effective movements. Han et al. propose a hierarchical framework that reuses pre-trained knowledge across various levels of task and perception. The cover image shows their quadrupedal robot MAX, developed by Tencent Robotics X, which demonstrates lifelike agility and strategic game-playing abilities.
See Han et al.
Image: Robotics X, Tencent Holdings Ltd. Cover design: Emily Paul",C,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_11.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_11.png,clip,4_11.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_6.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_6.png,groundtruth,6_6.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_5.png,vith,5_5.txt,train
NATURE REVIEWS NEUROSCIENCE,26_2,Which of the following options best describe the cover story?,"‘Structural similarity networks’, inspired by the Review on p42
Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,clip,15_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/23_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/23_5.png,vith,23_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,vitg,25_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/26_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/26_2.png,groundtruth,26_2.txt,val
Nature Chemical Biology,21_1,Which of the following options best describe the cover story?,"A blueprint for saponin synthesis
Saponarioside B, a saponin triterpenoid glycoside, is a potential precursor for the synthesis of pharmaceutical adjuvants. Jo et al. have now reported its complete biosynthetic pathway. The cover image is a botanical illustration of a Saponaria plant taken from a book in the rare book collection at the John Innes Centre.
See Jo et al.
Image: John Innes Historical Collections, courtesy of the John Innes Foundation. Cover design: Alex Wing",B,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_5.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_5.png,vith,14_5.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/21_1.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/21_1.png,groundtruth,21_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_12.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_12.png,vitg,13_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_1.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_1.png,clip,18_1.txt,train
Trends in Genetics,40_4,Which of the following options best describe the cover story?,"The brain is a genetic ‘mosaic’ comprising a patchwork of cells with
distinct DNA sequences. In this issue, Sahib Sran, Amanda Ringland, and Tracy
Bedrosian describe sources of genomic diversity that contribute to building the mosaic
brain. Expanding beyond the period of neurodevelopment, they consider complex
origins of brain mosaicism that arise throughout the entire lifespan from embryogenesis
through aging. Image credit: erhui1979/Getty Images.",C,MAC_Bench/Cell/Cover/Trends in Genetics/33_7.png,MAC_Bench/Cell/Cover/Trends in Genetics/33_7.png,vith,33_7.txt,MAC_Bench/Cell/Cover/Trends in Genetics/39_3.png,MAC_Bench/Cell/Cover/Trends in Genetics/39_3.png,clip,39_3.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_4.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_4.png,groundtruth,40_4.txt,MAC_Bench/Cell/Cover/Trends in Genetics/36_2.png,MAC_Bench/Cell/Cover/Trends in Genetics/36_2.png,vitg,36_2.txt,train
Nature Reviews Electrical Engineering,1_10,Which of the following options best describe the cover story?,"Human body digital twins can be created through the analysis and modelling of real physiological data coming from on-body sensors and medical devices. The cover image illustrates the duality between the real world and the virtual representation. See Occhipinti et al.
Cover design: Sam Whitham.",B,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,vith,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_10.png,groundtruth,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,vitg,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,clip,1_5.txt,val
Trends in Immunology,45_2,Which of the following options best describe the cover story?,"On pages 851–860, Murre and colleagues discuss how chromatin loop
extrusion and phase separation programs shape nuclear architecture, thus driving
mammalian polymorphonuclear cell fate decisions. The micrograph shows a blood
vessel in the human gallbladder that is filled with neutrophils. Magnification: 250X.
Image
credit: Ed Reschke/GettyImages.",A,MAC_Bench/Cell/Cover/Trends in Immunology/45_2.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_2.png,groundtruth,45_2.txt,MAC_Bench/Cell/Cover/Trends in Immunology/33_9.png,MAC_Bench/Cell/Cover/Trends in Immunology/33_9.png,clip,33_9.txt,MAC_Bench/Cell/Cover/Trends in Immunology/38_13.png,MAC_Bench/Cell/Cover/Trends in Immunology/38_13.png,vitg,38_13.txt,MAC_Bench/Cell/Cover/Trends in Immunology/41_13.png,MAC_Bench/Cell/Cover/Trends in Immunology/41_13.png,vith,41_13.txt,train
Nature Reviews Bioengineering,2_11,Which of the following options best describe the cover story?,"Single-cell RNA sequencing techniques and analysis methods can help improve our understanding of tissue injury responses and inform the design of new regenerative biomaterials and therapeutics. See Anna Ruta et al.
Cover image: Simon Bradbrook.",B,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,clip,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_11.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_11.png,groundtruth,2_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,vith,1_10.txt,train
CELL RESEARCH,34_2,Which of the following options best describe the cover story?,"Beneath the blazing sun, the guardian deity of agriculture wields the sacred sickle-shaped tool, TMS5, which removes cP from the cP-ΔCCA-tRNAs accumulated in rice, thereby safeguarding its fertility. In contrast, the rice left beyond his reach, burdened with cP-ΔCCA-tRNAs, remains sterile. See page 763–775 by Bin Yan et al. for details.",A,MAC_Bench/Nature/Cover/CELL RESEARCH/34_2.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_2.png,groundtruth,34_2.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/31_6.png,MAC_Bench/Nature/Cover/CELL RESEARCH/31_6.png,clip,31_6.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_8.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_8.png,vith,34_8.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_6.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_6.png,vitg,32_6.txt,train
Trends in Biochemical Sciences,49_1,Which of the following options best describe the cover story?,"Small heat shock proteins (sHsps) protect the proteome against
deleterious effects of protein unfolding, catching non-native proteins before they
aggregate and precipitate. On pages 1063–1078 in this issue, Johannes Buchner
and colleagues describe the structural and functional principles of sHsp oligomers
and what makes them versatile and adaptive for trapping a large range of non-native
proteins. Cover art, colors inspired by “The Catcher in the Rye”, by Carsten Peters.",C,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_5.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_5.png,vith,49_5.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/37_11.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/37_11.png,clip,37_11.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_1.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_1.png,groundtruth,49_1.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,vitg,50_2.txt,train
Journal of the American Chemical Society,2024_43,Which of the following options best describe the cover story?,"This study reveals two distinct pathways to synthesize hydrogels from random copolypeptides through ring-opening polymerization of N-carboxyanhydrides: rapid assembly into elongated fibril networks and the formation of robust fibril clusters, shaping the future of synthetic, biomimetic hydrogel design with custom-designed properties.",B,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2021_5.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2021_5.png,vith,2021_5.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_43.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_43.png,groundtruth,2024_43.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_11.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_11.png,vitg,2011_11.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_20.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_20.png,clip,2017_20.txt,train
Med,5_11,Which of the following options best describe the cover story?,"On the cover: Amputees often struggle with natural interaction due to missing sensory
feedback in their prostheses, including temperature perception. Muheim et al. utilize phantom thermal sensations to provide real-time temperature information about
grasped objects, via a standalone system integrated into a commercially available
prosthesis. This system can potentially improve prosthesis function and naturalness,
and greatly benefit amputees in daily tasks. Cover photograph by Jamani Caillet.",A,MAC_Bench/Cell/Cover/Med/5_11.png,MAC_Bench/Cell/Cover/Med/5_11.png,groundtruth,5_11.txt,MAC_Bench/Cell/Cover/Med/2_1.png,MAC_Bench/Cell/Cover/Med/2_1.png,ave_3,2_1.txt,MAC_Bench/Cell/Cover/Med/4_12.png,MAC_Bench/Cell/Cover/Med/4_12.png,ave_2,4_12.txt,MAC_Bench/Cell/Cover/Med/2_10.png,MAC_Bench/Cell/Cover/Med/2_10.png,clip,2_10.txt,train
Trends in Chemistry,6_10,Which of the following options best describe the cover story?,"Utilizing a biphasic solvent system in biorefining enables the efficient
conversion and separation of cellulose, hemicellulose, and lignin. In this month’s
systematic review article from Ragauskas, Wang and colleagues, the production
process of furans via classical biphasic systems is discussed, and an innovative design
of non-classical, sustainable biphasic systems for industrial applications is proposed.
The approach aims to reduce the overall complexity of the purification process, and
improve the production of furan-compounds and liquid fuels. Image credit: Dr. Kui
Wang",C,MAC_Bench/Cell/Cover/Trends in Chemistry/6_3.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_3.png,vitg,6_3.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_12.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_12.png,clip,6_12.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_10.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_10.png,groundtruth,6_10.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/5_11.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_11.png,vith,5_11.txt,train
Trends in Chemistry,6_11,Which of the following options best describe the cover story?,"Developing new medicines requires a huge amount of time, effort and
money to bring them to market, not to mention the negative environmental impacts
from the synthetic routes and chemicals used. All of these costs are then passed
onto the consumers - therefore those in low/limited income countries worldwide have
reduced access to life-saving medications that are sorely needed. In his Opinion
article, Professor Bruce Lipshutz makes the case that adhering to the Principles of
Green Chemistry, alongside new green technologies, can lead to more environmentally
responsible and cost-effective synthetic routes for manufacturing vital drug molecules,
benefitting the health and well-being of many across the globe. Image credit: Getty
Images/artpartner-images",A,MAC_Bench/Cell/Cover/Trends in Chemistry/6_11.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_11.png,groundtruth,6_11.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/3_10.png,MAC_Bench/Cell/Cover/Trends in Chemistry/3_10.png,vitg,3_10.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,clip,6_7.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,ave_2,6_8.txt,train
NATURE MEDICINE,30_10,Which of the following options best describe the cover story?,"Pancreatic cancer biomarkers
In this issue, Shi, Jin, Yin, Fang, Chen, Shen and colleagues use proteomic data to identify biomarkers of the response to adjuvant chemotherapy and develop a prognostic risk model for patients with pancreatic ductal adenocarcinoma. The cover depicts a pancreas compass with the needles symbolizing biomarkers, illustrating the potential for optimizing treatment management for patients with pancreatic cancer.
See Jiang et al.
Image: Baiyong Shen, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine. Cover design: Debbie Maizels",A,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_10.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_10.png,groundtruth,30_10.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_10.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_10.png,vitg,25_10.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_7.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_7.png,vith,25_7.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/12_8.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/12_8.png,clip,12_8.txt,train
ACS Sustainable Resource Management,2024_8,Which of the following options best describe the cover story?,"A novel stepwise alkaline route of ion-adsorption rare earth low-level radioactive residues enabled a substantial reduction in inventory and radioactivity, enrichment of rare earth elements, and resource recovery of valuable Al and U.",B,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,ave_3,2024_9.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,vith,2024_12.txt,test
Precision Chemistry,2024_1,Which of the following options best describe the cover story?,Cover illustrates nanometer-thick collector films of lithium batteries relying on a closely packed crossed-lamellar structure for excellent damage resistance.,D,MAC_Bench/ACS/Cover/Precision Chemistry/2024_7.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_7.png,clip,2024_7.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,ave_3,2024_5.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,ave_2,2023_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_1.png,groundtruth,2024_1.txt,test
Chemical Research in Toxicology,2024_9,Which of the following options best describe the cover story?,"Drugs of abuse and toxins include diverse drug classes and chemical properties, which has posed the greatest challenge for broad screening in routine toxicological analyses. This work evaluated an untargeted workflow for broad toxicological screening via 35 representative drugs of abuse and metabolites, represented on the left as chemical structures within whole blood. The resulting LC-QToF-MS data is convoluted (see the 3D mass, retention time, and intensity graph) but can be processed to positively identify analytes via their retention time, parent ion, and fragment ions, as exemplified by lorazepam.",A,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_9.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2018_9.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2018_9.png,clip,2018_9.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2016_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2016_8.png,vitg,2016_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_11.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_11.png,ave_1,2024_11.txt,train
Journal of Chemical Theory and Computation,2024_20,Which of the following options best describe the cover story?,"Through the lens of our rovibronic code, Duo, we have shown the adiabatic and diabatic representations for computing nuclear motion to be numerically equivalent. The relation between the adiabatic and diabatic diatomic potentials is shown at the bottom to be equal (in “weight”) through the unitary transformation, U.",A,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_20.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_20.png,groundtruth,2024_20.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,clip,2023_16.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,ave_2,2023_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_2.png,ave_3,2023_2.txt,val
Nature Plants,10_3,Which of the following options best describe the cover story?,"Rubisco as a pyruvate source
The Arabidopsis cue1-1 mutant lacks the main phosphoenolpyruvate (PEP) translocator and consequently displays a reticulated phenotype due to a deficiency in aromatic amino acid biosynthesis. It was instrumental in demonstrating that chloroplast terpenoid biosynthesis obtains its pyruvate from rubisco rather than PEP import.
See Evans, S. E. et al.
Image: Michael A. Phillips, University of Toronto – Mississauga, Canada.Cover design: Erin Dewalt",A,MAC_Bench/Nature/Cover/Nature Plants/10_3.png,MAC_Bench/Nature/Cover/Nature Plants/10_3.png,groundtruth,10_3.txt,MAC_Bench/Nature/Cover/Nature Plants/5_3.png,MAC_Bench/Nature/Cover/Nature Plants/5_3.png,ave_1,5_3.txt,MAC_Bench/Nature/Cover/Nature Plants/7_8.png,MAC_Bench/Nature/Cover/Nature Plants/7_8.png,clip,7_8.txt,MAC_Bench/Nature/Cover/Nature Plants/5_8.png,MAC_Bench/Nature/Cover/Nature Plants/5_8.png,ave_2,5_8.txt,train
innovation,5_4,Which of the following options best describe the cover story?,"On the cover: Liver transplantation is the most effective treatment for end-stage
liver disease. And the reconstitution of immune homeostasis post-transplant is critical
for the long-term survival. However, the dynamics of immune response patterns under
immunosuppressive therapy in post-transplant patients remain largely unexplored. Professor
Peng Zhihai's team at Xiang'an Hospital of Xiamen University utilized longitudinal
clinical multicohort and single-cell technologies to reveal the processes of immune
rejection and homeostasis remodeling after liver transplantation. Under immunosuppressive
treatment, the postoperative immune response pattern of stably restored transplant
patients underwent a dynamic evolution in one year, progressing through four stages
of immune responses, from which a series of molecular markers for the early detection
and proactive intervention of graft rejection were identified. On these findings,
Peng's team developed a four-stage clinical management framework, offering a more
refined guide to the clinical management of patients after liver transplantation.",D,MAC_Bench/Cell/Cover/innovation/5_1.png,MAC_Bench/Cell/Cover/innovation/5_1.png,clip,5_1.txt,MAC_Bench/Cell/Cover/innovation/3_4.png,MAC_Bench/Cell/Cover/innovation/3_4.png,ave_2,3_4.txt,MAC_Bench/Cell/Cover/innovation/5_5.png,MAC_Bench/Cell/Cover/innovation/5_5.png,vitg,5_5.txt,MAC_Bench/Cell/Cover/innovation/5_4.png,MAC_Bench/Cell/Cover/innovation/5_4.png,groundtruth,5_4.txt,train
Science Signaling,2007_415,Which of the following options best describe the cover story?,"COVER This week's Focus Issue highlights the nucleus (see the Editorial Guide [http://stke.sciencemag.org/cgi/content-embargo/abstract/sigtrans;2007/415/eg11]). Articles and resources at STKE focus on signaling within the nucleus, as well as transport between the nucleus and the cytoplasm. The image depicts an artist's rendition of a cell nucleus. [Image: Christopher Bickel , AAAS]",B,MAC_Bench/Science/Cover/Science Signaling/1_38.png,MAC_Bench/Science/Cover/Science Signaling/1_38.png,vitg,1_38.txt,MAC_Bench/Science/Cover/Science Signaling/2007_415.png,MAC_Bench/Science/Cover/Science Signaling/2007_415.png,groundtruth,2007_415.txt,MAC_Bench/Science/Cover/Science Signaling/4_157.png,MAC_Bench/Science/Cover/Science Signaling/4_157.png,clip,4_157.txt,MAC_Bench/Science/Cover/Science Signaling/3_114.png,MAC_Bench/Science/Cover/Science Signaling/3_114.png,vith,3_114.txt,val
ACS Applied Materials & Interfaces,2025_1,Which of the following options best describe the cover story?,Hexagonal boron nitride spontaneously formed at the interface between a molten nickel–boron solution and dinitrogen gas in a ReaxFF simulation at 1800 K.,C,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_30.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2024_30.png,ave_2,2024_30.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2020_6.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2020_6.png,clip,2020_6.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2019_29.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2019_29.png,vith,2019_29.txt,train
Nature Electronics,8_1,Which of the following options best describe the cover story?,"Quantum computing
Our 2025 technology of the year is quantum computing.
See Editorial
Image and cover design: Lauren Heslop.",A,MAC_Bench/Nature/Cover/Nature Electronics/8_1.png,MAC_Bench/Nature/Cover/Nature Electronics/8_1.png,groundtruth,8_1.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_7.png,MAC_Bench/Nature/Cover/Nature Electronics/7_7.png,ave_1,7_7.txt,MAC_Bench/Nature/Cover/Nature Electronics/6_6.png,MAC_Bench/Nature/Cover/Nature Electronics/6_6.png,clip,6_6.txt,MAC_Bench/Nature/Cover/Nature Electronics/4_8.png,MAC_Bench/Nature/Cover/Nature Electronics/4_8.png,vitg,4_8.txt,train
ACS Infectious Diseases,2025_2,Which of the following options best describe the cover story?,ᴅ-[5-11C]-glutamine was investigated and shown to have high sensitivity and specificity for the targeted detection and treatment monitoring of biofilm-associated infections. View the article.,B,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2025_2.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_8.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_3.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2023_3.png,vith,2023_3.txt,test
Trends in Parasitology,40_12,Which of the following options best describe the cover story?,"In communities where soil-transmitted helminths (STH) are endemic, the
parasite burden is aggregated in a heterogeneous manner whereby many people have a
low
worm burden, and a few people have a very high burden. Decades of STH control globally
has led to considerable gains in reducing this burden. However, as STH infection decreases,
the degree of aggregation of infection within individuals in a population increases.
Identifying
these remaining pockets of infection requires fine scale monitoring and evaluation
programmes that are rarely implemented within current national neglected tropical
disease
(NTD) control. In this issue of Trends of Parasitology, Maddren and Anderson review the
current WHO guidelines, using data from the Expanded Special Project for the Elimination
of NTDs (ESPEN) to suggest and discuss appropriate spatial scales for the validation
of
elimination as a public health problem of STH infection. Image credit: GettyImages/oxygen.",C,MAC_Bench/Cell/Cover/Trends in Parasitology/29_9.png,MAC_Bench/Cell/Cover/Trends in Parasitology/29_9.png,clip,29_9.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/37_9.png,MAC_Bench/Cell/Cover/Trends in Parasitology/37_9.png,vitg,37_9.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_12.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_12.png,groundtruth,40_12.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/28_3.png,MAC_Bench/Cell/Cover/Trends in Parasitology/28_3.png,ave_1,28_3.txt,train
NATURE MEDICINE,30_2,Which of the following options best describe the cover story?,"Tracking Patient Journeys
In this issue, Heumos and colleagues present ehrapy, an open-source framework which combines electronic healthcare records allowing for analysis of a patient’s journey through the healthcare system. On the cover, patients' journeys are visualized as taking place over a landscape, constructed of electronic healthcare records, and patients can travel across this landscape in many ways finishing in different places - for instance recovered or with chronic disease.
See Heumos et al.
Image: Su Suh, SciStories LLC. Cover design: Marina Spencer",B,MAC_Bench/Nature/Cover/NATURE MEDICINE/20_10.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/20_10.png,clip,20_10.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_2.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_2.png,groundtruth,30_2.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/29_4.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/29_4.png,vitg,29_4.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/24_3.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/24_3.png,vith,24_3.txt,train
Chem & Bio Engineering,2024_5,Which of the following options best describe the cover story?,"This review highlights recent advances in metal-free peptide stapling, showcasing efficient, selective, and multifunctional stapling strategies to foster innovative ideation among readers.",C,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,ave_2,2024_4.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_5.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,vith,2024_6.txt,train
Nature Neuroscience,27_8,Which of the following options best describe the cover story?,"Common chemicals harm oligodendrocytes.
Chemicals in household products may affect brain development through direct toxic effects on oligodendrocytes, the myelinating cells in the central nervous system. These chemicals can be found in many consumer products, including hair conditioners, disinfecting wipes, and mouthwash. Because oligodendrocytes can develop and myelinate throughout childhood, the chemicals may pose a significant health risk to children. This image depicts a setting in which a child may be exposed to the identified chemicals. In this image, a myelinated neuron and oligodendrocytes float in the water of a bathtub, where they are covered in quaternary compounds.
See Cohn et al.
Image: Ella Maru Studio. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/Nature Neuroscience/9_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/9_11.png,clip,9_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_8.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_8.png,groundtruth,27_8.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/16_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/16_9.png,vith,16_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/13_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/13_9.png,vitg,13_9.txt,train
ACS Materials Au,2025_1,Which of the following options best describe the cover story?,"Due to its unique properties, microneedles are a potential game-changer in advanced healthcare with a focus on drug delivery and diagnosis. Recently, the focus has been on developing new technologies for fabricating microneedles with improved performance. AI was used in the creation of the cover image.",D,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,ave_2,2024_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_2.png,clip,2022_2.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_4.png,vitg,2022_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Materials Au/2025_1.png,groundtruth,2025_1.txt,val
Accounts of Materials Research,2024_3,Which of the following options best describe the cover story?,"By intertwining with various physical properties, two-dimensional and interface superconductivity may give rise to diverse emergent quantum phenomena, including quantum Griffiths singularity with superconducting rare regions, bosonic anomalous metallic state modulated by periodic nanohole arrays, Ising superconductivity with large in-plane critical field, interfacial high-temperature superconductivity, interface-induced superconductivity, etc.  View the article.",A,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_3.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_12.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_12.png,ave_3,2021_12.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_12.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_12.png,vitg,2022_12.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_12.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_12.png,clip,2023_12.txt,test
CELL RESEARCH,35_2,Which of the following options best describe the cover story?,"The dual effects of glucocorticoids (GCs) are illustrated by bees. Left, low levels of GCs bind to the canonical high-affinity GC receptor (GR, the flower producing honey), mediating physiological and therapeutic effects. Right, high levels of GCs can also bind to the low-affinity receptor, tau, leading to bone loss and demonstrating pathological effects. See page 23–44 by Wenyu Fu et al. for details.",A,MAC_Bench/Nature/Cover/CELL RESEARCH/35_2.png,MAC_Bench/Nature/Cover/CELL RESEARCH/35_2.png,groundtruth,35_2.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,ave_3,34_10.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/35_1.png,MAC_Bench/Nature/Cover/CELL RESEARCH/35_1.png,clip,35_1.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/31_4.png,MAC_Bench/Nature/Cover/CELL RESEARCH/31_4.png,ave_2,31_4.txt,val
Macromolecules,2024_7,Which of the following options best describe the cover story?,"A peculiar order–order transition with transition zone between achiral double gyroid and chiral alternating gyroid can be observed in the self-assembly of chiral triblock terpolymers, giving optical activity for the alternating gyroid due to interchain chiral interaction with homochiral evolution from helical polymer chain to hierarchical superstructure via mesochiral self-assembly.",A,MAC_Bench/ACS/Cover/Macromolecules/2024_7.png,MAC_Bench/ACS/Cover/Macromolecules/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_20.png,MAC_Bench/ACS/Cover/Macromolecules/2024_20.png,ave_1,2024_20.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,vitg,2014_20.txt,train
NATURE REVIEWS IMMUNOLOGY,24_10,Which of the following options best describe the cover story?,"Membrane organisers, inspired by the Review on p193.
Cover design: Simon Bradbrook",B,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/15_4.png,clip,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_10.png,groundtruth,24_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_5.png,vith,19_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_6.png,vitg,23_6.txt,train
Joule,8_5,Which of the following options best describe the cover story?,"On the cover: The cover illustrates Wallington et al.’s comprehensive analysis of green hydrogen’s potential to decarbonize all transportation
modes. Electricity is generated by harnessing renewable energy sources such as solar
and wind to produce hydrogen through electrolysis. This hydrogen, along with direct
renewable electricity, powers a variety of vehicles. The image captures the entire
spectrum of transportation modes: road vehicles, trains, aircraft, and ships, all
contributing to a more sustainable future. Image credit: Stephen Alvey and Joaquim
R.R.A. Martins.",B,MAC_Bench/Cell/Cover/Joule/4_2.png,MAC_Bench/Cell/Cover/Joule/4_2.png,clip,4_2.txt,MAC_Bench/Cell/Cover/Joule/8_5.png,MAC_Bench/Cell/Cover/Joule/8_5.png,groundtruth,8_5.txt,MAC_Bench/Cell/Cover/Joule/5_6.png,MAC_Bench/Cell/Cover/Joule/5_6.png,vith,5_6.txt,MAC_Bench/Cell/Cover/Joule/7_7.png,MAC_Bench/Cell/Cover/Joule/7_7.png,vitg,7_7.txt,val
Cell Chemical Biology,31_8,Which of the following options best describe the cover story?,"On the cover: Chen et al. identified a small molecule, C646, that directly targets the nuclear export factor,
Exportin-1 (XPO1), and induces its degradation. Furthermore, the chromatin localization
of histone methyltransferase p300 is also abrogated, explaining why C646 previously
showed phenotypes expected of p300 inhibition. Covalently targeting XPO1 represents
a unique approach to disrupting the chromatin localization of numerous factors (multi-colored
complex on top right), including XPO1 and p300. Image credit: Ella Maru Studios.",B,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_13.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_13.png,clip,31_13.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_8.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_8.png,groundtruth,31_8.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/17_6.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/17_6.png,vitg,17_6.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_12.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_12.png,vith,18_12.txt,train
Trends in Plant Science,29_1,Which of the following options best describe the cover story?,"Current knowledge about how plants tolerate the effects of soil calcium
carbonate (CaCO3) primarily focuses on iron (Fe) acquisition. However, CaCO3
affects plant mineral nutrition well beyond its influence on Fe metabolism, creating
challenges for crop growth and quality in calcareous agro-systems. Thibaut Bontpart,
Stéphane Mari, and their colleagues provide an update on the cellular and molecular
mechanisms that plants use to mitigate the negative impacts of CaCO3 in soils. They
also discuss recent efforts to identify genetic traits associated with CaCO3 tolerance
in natural populations, which could be utilized for breeding CaCO3-tolerant crops.
Furthermore, they review how environmental factors such as soil water content,
air CO2 levels, and temperature affect soil CaCO3 equilibrium and plant tolerance
to calcareous soils, proposing strategies for improvement amid climate change
challenges. Image credit: Chloe Kim.",B,MAC_Bench/Cell/Cover/Trends in Plant Science/28_4.png,MAC_Bench/Cell/Cover/Trends in Plant Science/28_4.png,vitg,28_4.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_1.png,groundtruth,29_1.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/18_10.png,MAC_Bench/Cell/Cover/Trends in Plant Science/18_10.png,clip,18_10.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/20_12.png,MAC_Bench/Cell/Cover/Trends in Plant Science/20_12.png,vith,20_12.txt,train
Journal of Chemical Education,2021_11,Which of the following options best describe the cover story?,"–and demonstrates redox chemistry that allows for the direct conversion of chemical energy to mechanical energy without involving a machine to accomplish the transfer. The visual effect is mesmerizing and provides a compelling introduction to the rich underlying science; however, the difficulty and time required to initiate and maintain regular oscillations often frustrates instructors and students, discouraging many from presenting this demonstration. In ""Resuscitating the Mercury Beating Heart: An Improvement on the Classic Demo"" (DOI: 10.1021/acs.jchemed.0c00845), Daniel Stribling, Christopher R. Brewer, and Kenneth A. Goldsby describe a simple device for reducing the setup time and increasing the duration of this classic yet underutilized chemical demonstration.",A,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_11.png,groundtruth,2021_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2016_2.png,vith,2016_2.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2012_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2015_9.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2015_9.png,vitg,2015_9.txt,train
Trends in Ecology & Evolution,39_8,Which of the following options best describe the cover story?,"Animals, such as Singapore parrotfish, Scarus prasiognathos, shown here,
transport energy and nutrients through food webs and across ecosystem boundaries.
While energy and nutrient fluxes can be measured for individual animals, scaling up
these individual processes to entire communities is difficult, particularly in high-diversity
systems such as coral reefs. On pages 467−478, James Robinson and colleagues argue
that filling data gaps and combining flux frameworks with existing ecosystem tools
will
improve quantitative predictions, which will advance our understanding of how fishes
contribute to ecosystem functions and services. Photo credit: Tane Sinclair-Taylor.",D,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/38_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/38_1.png,vitg,38_1.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/27_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/27_1.png,clip,27_1.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_2.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/29_2.png,ave_3,29_2.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_8.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_8.png,groundtruth,39_8.txt,train
NATURE REVIEWS NEUROSCIENCE,25_12,Which of the following options best describe the cover story?,"‘SARS-CoV-2 and the brain’, inspired by the Review on p30.
Cover design: Jennie Vallis",A,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_12.png,groundtruth,25_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/14_6.png,vitg,14_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/15_10.png,clip,15_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/21_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/21_9.png,vith,21_9.txt,val
NATURE REVIEWS IMMUNOLOGY,24_1,Which of the following options best describe the cover story?,"Storm, inspired by the Perspective on p912.
Cover design: Simon Bradbrook",A,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_1.png,groundtruth,24_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/20_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/20_9.png,clip,20_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_3.png,ave_3,23_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/23_12.png,vitg,23_12.txt,train
Journal of Chemical Theory and Computation,2024_16,Which of the following options best describe the cover story?,"The viscosity of deep eutectic solvents (DESs) holds significant influence across diverse research applications. Understanding and predicting DES viscosity is crucial for advancing various scientific projects. We developed different machine learning models for the prediction of DESs viscosity using the physics-informed input features, and these models help to accelerate the development of novel DESs.",B,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,vith,2023_16.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_16.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_16.png,groundtruth,2024_16.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_2.png,clip,2023_2.txt,train
Nature Machine Intelligence,7_1,Which of the following options best describe the cover story?,"Exploring causality, dynamics and cognition with LLMs
Modern vision-based large language models (LLMs) appear remarkably human-like at first glance. However, when tested on canonical psychology experiments, they fall short of human capabilities in predicting complex physical interactions, causal relationships, and intuitive understanding of others’ preferences. The image shows an embodied agent playing pool and aiming at a block tower, illustrating the experiments that the models were tested on.
See Schulze Buschoff et al.
Image: Elif Akata, Helmholtz Munich. Cover design: Vanitha Selvarajan",D,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_5.png,vith,2_5.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_5.png,vitg,4_5.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/1_7.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/7_1.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/7_1.png,groundtruth,7_1.txt,train
Nature Metabolism,6_8,Which of the following options best describe the cover story?,"Small vesicles as metabolic mediators
Small extracellular vesicles released from adipose tissue macrophages in mice that were treated with the anti-diabetic drug rosiglitazone improve insulin sensitivity in obese mice, circumventing the severe adverse effects of the drug. The image is an illustration of human cells secreting small extracellular vesicles.
See Rohm et al.
Credit: Image: JUAN GAERTNER/SCIENCE PHOTO LIBRARY. Cover Design: Thomas Phillips.",D,MAC_Bench/Nature/Cover/Nature Metabolism/4_12.png,MAC_Bench/Nature/Cover/Nature Metabolism/4_12.png,clip,4_12.txt,MAC_Bench/Nature/Cover/Nature Metabolism/4_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/4_9.png,vith,4_9.txt,MAC_Bench/Nature/Cover/Nature Metabolism/1_6.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_8.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_8.png,groundtruth,6_8.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_2,Which of the following options best describe the cover story?,"Intestinal organ chips, inspired by the Review on p751.
Cover design: Laura Marshall",C,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_8.png,vith,19_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,clip,20_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,groundtruth,21_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_2.png,ave_2,20_2.txt,val
Chem & Bio Engineering,2024_1,Which of the following options best describe the cover story?,"This study establishes CRISPO, an efficient tool for multicopy integration and pathway optimization in Pichia pastoris. By combining rDNA integration and fluorescence screening, CRISPO facilitates the construction of a yeast cell factory capable of producing geraniol at the highest titer and productivity ever reported.",C,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,vitg,2024_7.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,ave_2,2024_4.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_1.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,clip,2024_2.txt,test
Chemistry of Materials,2025_4,Which of the following options best describe the cover story?,"The cover art visually captures the fusion of nanomaterials with mitochondria targeting, imaging, and image-guided treatment. The mitochondria are targeted by floating molecules, such as rhodamine and",D,MAC_Bench/ACS/Cover/Chemistry of Materials/2018_24.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2018_24.png,vith,2018_24.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2017_11.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2017_11.png,ave_1,2017_11.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2015_15.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2015_15.png,clip,2015_15.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2025_4.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2025_4.png,groundtruth,2025_4.txt,train
Cell Chemical Biology,31_2,Which of the following options best describe the cover story?,"On the cover: Bacterial respiration is the primary pathway to produce energy, coupling
with the electron transport chain (ETC) to transfer electrons. Targeting the ETC leads
to energy depletion and bacterial death. In this cover by Li et al., bacteria are depicted as the glowing light bulbs equipped with electrical circuits.
Antibacterial compounds block electron transfer leading to bacterial death, which
is like interruption of circuits causing the lights to turn off. Hence, targeting
the ETC is an attractive strategy to discover antibiotics. Image credit: Kui Zhu and
Qian Li.",D,MAC_Bench/Cell/Cover/Cell Chemical Biology/21_1.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/21_1.png,clip,21_1.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/30_8.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/30_8.png,vith,30_8.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/26_1.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/26_1.png,vitg,26_1.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_2.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_2.png,groundtruth,31_2.txt,train
Science Robotics,9_93,Which of the following options best describe the cover story?,"ONLINE COVER A Variable-Stiffness Deformable Wheel. Wheels have a low cost of transport over flat ground but struggle to overcome large obstacles. Inspired by the surface tension of a water droplet, Lee et al. developed a morphing wheel that rolls over flat ground in the circular high-modulus state and deforms over obstacles in the low-modulus state. The modulus of the wheel is changed in real time by adjusting the tension in the spoke structure. This month’s cover depicts a two-wheeled mobile platform with variable-stiffness wheels in the low-modulus state rolling over an irregularly shaped rock outdoors. Credit: Korea Institute of Machinery and Materials, photo by Sinabro Studio",B,MAC_Bench/Science/Cover/Science Robotics/6_53.png,MAC_Bench/Science/Cover/Science Robotics/6_53.png,clip,6_53.txt,MAC_Bench/Science/Cover/Science Robotics/9_93.png,MAC_Bench/Science/Cover/Science Robotics/9_93.png,groundtruth,9_93.txt,MAC_Bench/Science/Cover/Science Robotics/2_10.png,MAC_Bench/Science/Cover/Science Robotics/2_10.png,ave_2,2_10.txt,MAC_Bench/Science/Cover/Science Robotics/2_5.png,MAC_Bench/Science/Cover/Science Robotics/2_5.png,vith,2_5.txt,train
Precision Chemistry,2024_12,Which of the following options best describe the cover story?,"A proline-catalyzed aldol condensation of a glycine Schiff base was developed for the synthesis of α,β-dehydroamino acid derivatives. The synthesized α,β-dehydroamino acid derivatives could be incorporated into peptides not only at the C-terminal but also at the N-terminal.",C,MAC_Bench/ACS/Cover/Precision Chemistry/2023_9.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_9.png,clip,2023_9.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,vith,2025_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_12.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_2.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_2.png,vitg,2024_2.txt,val
Nature Sustainability,7_11,Which of the following options best describe the cover story?,"Recovering and resourcing from manure wastewater
Recovering ammonia from manure wastewater has multiple sustainability benefits. Qin and colleagues develop an electrochemical process that allows such removal efficiently and enables the production of decentralized fertilizers and chemicals.
See Wang et al.
Credit: Matauw, Getty Images. Cover Design: Alex Whitworth.",C,MAC_Bench/Nature/Cover/Nature Sustainability/7_9.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_9.png,vith,7_9.txt,MAC_Bench/Nature/Cover/Nature Sustainability/2_8.png,MAC_Bench/Nature/Cover/Nature Sustainability/2_8.png,clip,2_8.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_11.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_11.png,groundtruth,7_11.txt,MAC_Bench/Nature/Cover/Nature Sustainability/1_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/1_4.png,vitg,1_4.txt,val
Nature Plants,10_10,Which of the following options best describe the cover story?,"Spreading the load
Centromeres affect epigenomic architecture and meiotic recombination. The Brazillian plant Rhynchospora breviuscula has holocentric chromosomes with multiple kinetochores along their length, rather than a single centromere. Here, chromosome synapsis dynamics is key to the broad-scale pattern of crossovers. The image shows anthers, pollen and meiocyte of R. breviuscula.
See Castellan et al.
Image: Ulla Neumann, Marco Castellani, Thiago do Nascimento and Rob Kesseler. Cover Design: Erin Dewalt.",D,MAC_Bench/Nature/Cover/Nature Plants/6_2.png,MAC_Bench/Nature/Cover/Nature Plants/6_2.png,vith,6_2.txt,MAC_Bench/Nature/Cover/Nature Plants/7_2.png,MAC_Bench/Nature/Cover/Nature Plants/7_2.png,vitg,7_2.txt,MAC_Bench/Nature/Cover/Nature Plants/8_13.png,MAC_Bench/Nature/Cover/Nature Plants/8_13.png,clip,8_13.txt,MAC_Bench/Nature/Cover/Nature Plants/10_10.png,MAC_Bench/Nature/Cover/Nature Plants/10_10.png,groundtruth,10_10.txt,train
Cell Stem Cell,31_12,Which of the following options best describe the cover story?,"On the cover: In this issue, Beumer and Clevers put forth a set of six complementary hallmarks that are key enabling features of
stemness in adult mammalian tissues. The review headlines a broader series of articles
appearing throughout the year that applies the hallmarks framework to define distinct aspects of stem cell biology as shown on the cover,
spanning from stem cell aging, metabolism, and potency to cancer stem cells and tissue
regeneration. Cover art by Phillip Krzeminski.",A,MAC_Bench/Cell/Cover/Cell Stem Cell/31_12.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_12.png,groundtruth,31_12.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/24_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/24_1.png,vith,24_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/10_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/10_2.png,clip,10_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/9_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/9_1.png,vitg,9_1.txt,test
Precision Chemistry,2025_2,Which of the following options best describe the cover story?,"Building two-dimensional, ordered carbon–carbon networks with precise, deterministic monomer coupling at the interface enables the creation of 2D porous, semiconducting nanomembranes.",C,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,vitg,2024_6.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,clip,2024_5.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2025_2.png,MAC_Bench/ACS/Cover/Precision Chemistry/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,ave_1,2023_1.txt,train
ACS Infectious Diseases,2024_10,Which of the following options best describe the cover story?,"Bi(III)-based compounds can allosterically target a SARS-CoV-2 nsp14/nsp10 complex to disrupt its MTase and ExoN activity, leading to inhibition of SARS-CoV-2 replication in mammalian cells, which is attributable to the Bi compounds’ ability to displace zinc ions from the zinc-finger sites of the nsp14/nsp10 complex and",D,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_6.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_6.png,vitg,2024_6.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2025_1.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2025_1.png,vith,2025_1.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_8.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png,groundtruth,2024_10.txt,train
Trends in Microbiology,32_10,Which of the following options best describe the cover story?,"Traits-based approaches have gained increasing attention for
studying plant–microbe interactions especially from an ecological standpoint.
However, many of the functional traits currently used pose a significant problem:
high intraspecific variations. In order to address this, in the current issue, Dr.
Zhang
and colleagues consider plant genome size as a trait that can be harnessed to study
microbiome-mediated interactions and adaptations to environmental changes.
Image courtesy: GettyImages (Andriy Onufriyenko)",A,MAC_Bench/Cell/Cover/Trends in Microbiology/32_10.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_10.png,groundtruth,32_10.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/21_6.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_6.png,ave_2,21_6.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/25_3.png,MAC_Bench/Cell/Cover/Trends in Microbiology/25_3.png,clip,25_3.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/31_5.png,MAC_Bench/Cell/Cover/Trends in Microbiology/31_5.png,vitg,31_5.txt,train
Science Signaling,2007_417,Which of the following options best describe the cover story?,"COVER This week features a Protocol that describes how to used engineered thioredoxin to identify redox-reactive cell surface proteins. The image is reduced recombinant human thioredoxin based on PDB 3trx. [Image: Christopher Bickel, AAAS]",B,MAC_Bench/Science/Cover/Science Signaling/1_48.png,MAC_Bench/Science/Cover/Science Signaling/1_48.png,clip,1_48.txt,MAC_Bench/Science/Cover/Science Signaling/2007_417.png,MAC_Bench/Science/Cover/Science Signaling/2007_417.png,groundtruth,2007_417.txt,MAC_Bench/Science/Cover/Science Signaling/5_245.png,MAC_Bench/Science/Cover/Science Signaling/5_245.png,vith,5_245.txt,MAC_Bench/Science/Cover/Science Signaling/5_250.png,MAC_Bench/Science/Cover/Science Signaling/5_250.png,vitg,5_250.txt,train
ACS Sensors,2024_4,Which of the following options best describe the cover story?,"The low bias (0.5 V) boosts a 7-fold-increased response in the Au/SnO2 H2S gas sensor with the benefit from the interface dipoles in the flower-petal-like nanostructures. With a 2 ppb limit of detection at room temperature, the sensor is ideal for environmental and breath disease monitoring.",D,MAC_Bench/ACS/Cover/ACS Sensors/2016_11.png,MAC_Bench/ACS/Cover/ACS Sensors/2016_11.png,ave_2,2016_11.txt,MAC_Bench/ACS/Cover/ACS Sensors/2019_3.png,MAC_Bench/ACS/Cover/ACS Sensors/2019_3.png,clip,2019_3.txt,MAC_Bench/ACS/Cover/ACS Sensors/2022_8.png,MAC_Bench/ACS/Cover/ACS Sensors/2022_8.png,vith,2022_8.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_4.png,groundtruth,2024_4.txt,val
Trends in Biotechnology,42_10,Which of the following options best describe the cover story?,"The rising threat of multi-drug resistant infections has brought
bacteriophage into the spotlight, with advances in sequencing technologies and genetic
engineering techniques enabling rapid development of engineered phage therapeutics.
In pages 326–338 of this issue, Schmitt and colleagues discuss applications of designer
phage containing recombinant gene payloads to enhance antimicrobial activity and
manipulate the microbiome. Cover image from Jason Whitley, Senior Instructional
Designer, BTEC.",D,MAC_Bench/Cell/Cover/Trends in Biotechnology/31_7.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/31_7.png,vith,31_7.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_7.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_7.png,vitg,42_7.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/33_13.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/33_13.png,clip,33_13.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_10.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_10.png,groundtruth,42_10.txt,test
Neuron,113_1,Which of the following options best describe the cover story?,"On the cover: In this special issue of Neuron, we present a collection of reviews and perspectives on the neurobiology of aging.
The causes of brain aging are multidimensional and complex. Highlighting this, the
cover image is provided by Schwartz and colleagues, who discuss the impact of the immune system on brain aging and propose the provocative
idea of anti-aging immune therapy.",A,MAC_Bench/Cell/Cover/Neuron/113_1.png,MAC_Bench/Cell/Cover/Neuron/113_1.png,groundtruth,113_1.txt,MAC_Bench/Cell/Cover/Neuron/75_4.png,MAC_Bench/Cell/Cover/Neuron/75_4.png,ave_3,75_4.txt,MAC_Bench/Cell/Cover/Neuron/113_4.png,MAC_Bench/Cell/Cover/Neuron/113_4.png,clip,113_4.txt,MAC_Bench/Cell/Cover/Neuron/73_3.png,MAC_Bench/Cell/Cover/Neuron/73_3.png,ave_2,73_3.txt,test
Molecular Plant,17_12,Which of the following options best describe the cover story?,"On the cover: The cover image illustrates a leaf of the fern Ceratopteris richardii infected by the pathogenic fungus Sclerotinia scleroriorum. An angiosperm pathogen can infect a non-angiosperm plant, suggesting at least partial
conservation of molecular regulation of plant-microbe interactions. Overlay of real
colour image and 488nm-excited fluorescent image after dye with GFP-conjugated Wheat
Germ Agglutin, known to bind chitin. Image by Baptiste CASTEL with the assistance
of NightCafé (https://creator.nightcafe.studio).",C,MAC_Bench/Cell/Cover/Molecular Plant/9_6.png,MAC_Bench/Cell/Cover/Molecular Plant/9_6.png,vith,9_6.txt,MAC_Bench/Cell/Cover/Molecular Plant/14_3.png,MAC_Bench/Cell/Cover/Molecular Plant/14_3.png,clip,14_3.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_12.png,MAC_Bench/Cell/Cover/Molecular Plant/17_12.png,groundtruth,17_12.txt,MAC_Bench/Cell/Cover/Molecular Plant/16_1.png,MAC_Bench/Cell/Cover/Molecular Plant/16_1.png,vitg,16_1.txt,train
Nature Geoscience,17_7,Which of the following options best describe the cover story?,"Tibetan Plateau lake expansion
Model projections suggest that, even under a low emissions scenario, lakes on the Tibetan Plateau will increase in area by about 50% by 2100, with widespread impacts on infrastructure and ecosystems. The photo shows the Dawa Co (left) and Qiduo Co (right) lakes, the land between which is gradually disappearing due to rising lake levels.
See Zhang et al.
Image: Shi Cai. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/15_6.png,MAC_Bench/Nature/Cover/Nature Geoscience/15_6.png,vitg,15_6.txt,MAC_Bench/Nature/Cover/Nature Geoscience/16_9.png,MAC_Bench/Nature/Cover/Nature Geoscience/16_9.png,ave_1,16_9.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_7.png,groundtruth,17_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/14_12.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_12.png,clip,14_12.txt,train
Nature Cancer,5_4,Which of the following options best describe the cover story?,"Multiomics profiling of immunotherapy-induced toxicities
Multiomics profiling identifies a targetable role for type III-associated immune responses in the development of immunotherapy-induced toxicities in melanoma.
See Dimitriou et al.
Image: Phil F. Cheng and Federica Sella, University Hospital of Zurich. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Cancer/5_4.png,MAC_Bench/Nature/Cover/Nature Cancer/5_4.png,groundtruth,5_4.txt,MAC_Bench/Nature/Cover/Nature Cancer/1_8.png,MAC_Bench/Nature/Cover/Nature Cancer/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Cancer/1_10.png,MAC_Bench/Nature/Cover/Nature Cancer/1_10.png,vith,1_10.txt,MAC_Bench/Nature/Cover/Nature Cancer/2_6.png,MAC_Bench/Nature/Cover/Nature Cancer/2_6.png,clip,2_6.txt,train
Caner Cell,42_4,Which of the following options best describe the cover story?,"On the cover: Watson et al. integrate multi-omics approaches to investigate how the glioblastoma microenvironment
responds to different treatment interventions and discover how treatment-associated
fibrosis can protect surviving tumor cells and promote eventual recurrence. This four-part
image depicts a mouse glioblastoma with renderings of high-dimensional imaging, single-cell
RNA sequencing, mass spectrometry proteomic analysis, and spatial transcriptomics,
respectively in clockwise sequence. Credit: Spencer Watson, Anoek Zomer, and Johanna
Joyce.",B,MAC_Bench/Cell/Cover/Caner Cell/28_4.png,MAC_Bench/Cell/Cover/Caner Cell/28_4.png,vitg,28_4.txt,MAC_Bench/Cell/Cover/Caner Cell/42_4.png,MAC_Bench/Cell/Cover/Caner Cell/42_4.png,groundtruth,42_4.txt,MAC_Bench/Cell/Cover/Caner Cell/30_1.png,MAC_Bench/Cell/Cover/Caner Cell/30_1.png,clip,30_1.txt,MAC_Bench/Cell/Cover/Caner Cell/35_2.png,MAC_Bench/Cell/Cover/Caner Cell/35_2.png,vith,35_2.txt,train
Accounts of Chemical Research,2024_16,Which of the following options best describe the cover story?,"Heterogeneous nanocrystal formation with metals controlled by electrostatic force, ion enrichment, and interfacial energy through metal",C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_9.png,vitg,2020_9.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_12.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_12.png,ave_2,2020_12.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_16.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_16.png,groundtruth,2024_16.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2013_8.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2013_8.png,clip,2013_8.txt,train
ACS Sensors,2024_12,Which of the following options best describe the cover story?,"A novel Aggregation-Induced Emission (AIE)-based fluorescent sensor for imaging the spatial organization of HER2 receptors on the membrane of HER2 overexpressing cancer cells. When the receptors are clustered, the molecules undergo a reversible “turn-on” process. The clusters are disrupted upon exposure to an immunotherapy (Trastuzumab), reducing the emission.",A,MAC_Bench/ACS/Cover/ACS Sensors/2024_12.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Sensors/2016_7.png,MAC_Bench/ACS/Cover/ACS Sensors/2016_7.png,clip,2016_7.txt,MAC_Bench/ACS/Cover/ACS Sensors/2020_2.png,MAC_Bench/ACS/Cover/ACS Sensors/2020_2.png,vith,2020_2.txt,MAC_Bench/ACS/Cover/ACS Sensors/2017_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2017_4.png,vitg,2017_4.txt,val
NATURE REVIEWS IMMUNOLOGY,24_4,Which of the following options best describe the cover story?,"Generating mosquito immunity, inspired by the Review on p621.
Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_2.png,ave_1,14_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_9.png,vitg,19_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_4.png,groundtruth,24_4.txt,train
CELL RESEARCH,34_1,Which of the following options best describe the cover story?,"This image depicts a story of a powerful AI comet merging in the life science universe. The information in millions of single-cell transcriptomes was distilled to create a large foundation model named GeneCompass, which uses cutting-edge foundation model AI technologies to decipher universal gene regulatory mechanisms and shows tremendous potential for accelerating advancements in life science research.See page 830–845 by Xiaodong Yang et al. for details.",A,MAC_Bench/Nature/Cover/CELL RESEARCH/34_1.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_1.png,groundtruth,34_1.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_2.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_2.png,vitg,32_2.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_4.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_4.png,clip,34_4.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/30_2.png,MAC_Bench/Nature/Cover/CELL RESEARCH/30_2.png,vith,30_2.txt,val
Trends in Biotechnology,42_8,Which of the following options best describe the cover story?,"Urethral conditions impact children and adults, increasing the risk of
urinary tract infections, voiding and sexual dysfunction, and renal failure. 3D bioprinting
can revolutionize personalized urethral repairs, adapting to individual anatomical
variations
and disease characteristics with customizable physical properties. In pages 544–559
of this issue, Booth and colleagues discuss the emerging applications of 3D bioprinting
technologies to address ongoing challenges in urethral tissue engineering, including
biomechanical and structural mismatch, lack of individualized repair solutions, and
inadequate wound healing and vascularization. Cover image from the team of Inmywork
Studio (https://inmywork.com/).",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_8.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_8.png,groundtruth,42_8.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/37_6.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/37_6.png,clip,37_6.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/33_4.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/33_4.png,vith,33_4.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_2.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_2.png,vitg,42_2.txt,train
Molecular Plant,17_2,Which of the following options best describe the cover story?,"On the cover: Pathogens and their hosts are engaged in an ever-evolving arms race. Host pattern-recognition
receptors detect invading fungi and recruit adaptor proteins to initiate a signaling
cascade that ultimately triggers immune responses. In maize, the plasma-membrane-localized
receptor ZmWAK recognizes an unknown signature from the fungal pathogen Sporisorium reilianum and relays the phosphorylation signal to the cytoplastic kinase ZmSnRK1α2, thereby
facilitating its translocation into the nucleus for promoting the degradation of ZmWRKY53.
The reduced accumulation of ZmWRKY53, in turn, causes the downregulated expression
of transmembrane transporter genes, thereby restricting nutrient acquisition by Sporisorium reilianum in the apoplasts. Therefore, the ZmWAK-SnRK1α2-WRKY53 signaling module underlies
quantitative resistance to head smut disease in maize. The cover portrays this host-pathogen
conflict with a personified depiction, showing the soldiers in battle defending their
supplies with a strategic counterattack against the enemies. Image by Mingzhu Yan.",D,MAC_Bench/Cell/Cover/Molecular Plant/10_2.png,MAC_Bench/Cell/Cover/Molecular Plant/10_2.png,clip,10_2.txt,MAC_Bench/Cell/Cover/Molecular Plant/12_5.png,MAC_Bench/Cell/Cover/Molecular Plant/12_5.png,vitg,12_5.txt,MAC_Bench/Cell/Cover/Molecular Plant/12_3.png,MAC_Bench/Cell/Cover/Molecular Plant/12_3.png,vith,12_3.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_2.png,MAC_Bench/Cell/Cover/Molecular Plant/17_2.png,groundtruth,17_2.txt,train
Current Biology,34_19,Which of the following options best describe the cover story?,"On the cover: There is more than meets the eye in this female Phalangium opilio, an arachnid commonly known as daddy-longlegs. Daddy-longlegs were always thought
to have just two eyes, which sit on top of a periscope-like projection of the head.
In this issue, Gainett et al. provide neuroanatomic and genetic evidence that extant daddy-longlegs have additional
vestigial eyes, which correspond to those previously described in four-eyed fossils
from the Carboniferous. This discovery impacts the phylogenetic position of these
fossils and age estimates for the origin of the group and underscores the importance
of vestigial organs for understanding evolution. Photograph © Roman Willi; used with
permission.",B,MAC_Bench/Cell/Cover/Current Biology/28_11.png,MAC_Bench/Cell/Cover/Current Biology/28_11.png,vith,28_11.txt,MAC_Bench/Cell/Cover/Current Biology/34_19.png,MAC_Bench/Cell/Cover/Current Biology/34_19.png,groundtruth,34_19.txt,MAC_Bench/Cell/Cover/Current Biology/24_10.png,MAC_Bench/Cell/Cover/Current Biology/24_10.png,ave_3,24_10.txt,MAC_Bench/Cell/Cover/Current Biology/28_19.png,MAC_Bench/Cell/Cover/Current Biology/28_19.png,clip,28_19.txt,train
Nature Reviews Psychology,3_10,Which of the following options best describe the cover story?,"A sense of belonging can provide LGBTQ+ people with the opportunity to thrive and promote psychological well-being. In this Review, Matsick et al. summarize factors that influence belonging based on sexual orientation and gender.
Cover design: David Johnston",C,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_3.png,vitg,1_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_5.png,vith,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_10.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_10.png,groundtruth,3_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_2.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_2.png,clip,1_2.txt,val
Cell Reports,43_8,Which of the following options best describe the cover story?,"On the cover: An artificially colored scanning electron micrograph of a butterfly
wing demonstrating the diversity of scale cell types, including paddle-shaped scales
and long, pronged scales at the margin. In this issue, Prakash et al. generate a single-cell atlas of Bicyclus anynana butterfly pupal forewings and identify markers of different cell types, including
scale cells. Photo credit: Anupama Prakash.",A,MAC_Bench/Cell/Cover/Cell Reports/43_8.png,MAC_Bench/Cell/Cover/Cell Reports/43_8.png,groundtruth,43_8.txt,MAC_Bench/Cell/Cover/Cell Reports/24_13.png,MAC_Bench/Cell/Cover/Cell Reports/24_13.png,vitg,24_13.txt,MAC_Bench/Cell/Cover/Cell Reports/23_6.png,MAC_Bench/Cell/Cover/Cell Reports/23_6.png,vith,23_6.txt,MAC_Bench/Cell/Cover/Cell Reports/15_9.png,MAC_Bench/Cell/Cover/Cell Reports/15_9.png,clip,15_9.txt,train
Cell Stem Cell,31_10,Which of the following options best describe the cover story?,"On the cover: In this issue, Hu et al. report on the hypoimmune editing of primary non-human primate islets that can be
transplanted into an allogeneic recipient and reverse diabetes. The cover illustrates
a monkey standing on a pancreas-shaped stone and introducing a gene-edited hypoimmune
islet organoid to the world. Cover art by Justin A. Klein and Emily Cheng for Mito
Pop.",D,MAC_Bench/Cell/Cover/Cell Stem Cell/29_10.png,MAC_Bench/Cell/Cover/Cell Stem Cell/29_10.png,vitg,29_10.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/29_9.png,MAC_Bench/Cell/Cover/Cell Stem Cell/29_9.png,vith,29_9.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/13_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/13_2.png,clip,13_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_10.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_10.png,groundtruth,31_10.txt,train
Accounts of Chemical Research,2024_11,Which of the following options best describe the cover story?,Dirhodium tetracarboxylate-promoted reactions have served as a proving ground for modern computational chemistry methods. The applied theoretical chemistry of such reactions regularly has led to new models of organometallic reactivity. Key developments include the rise of,A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_11.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2017_8.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2017_8.png,vitg,2017_8.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_6.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_6.png,clip,2022_6.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2010_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2010_2.png,vith,2010_2.txt,train
NATURE REVIEWS MICROBIOLOGY,23_1,Which of the following options best describe the cover story?,"Harnessing the microbiome for sustainable crop production, inspired by the Review on p9
Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_8.png,vitg,14_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/23_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/23_2.png,clip,23_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/23_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/23_1.png,groundtruth,23_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_2.png,vith,19_2.txt,val
Nature Electronics,7_12,Which of the following options best describe the cover story?,"Recapture and reuse
With the help of processes that can recycle organic conductors, semiconductors and dielectrics, flexible electronic devices can be created in which each component of the device can be recaptured and reused. The computer-generated image on the cover shows a flexible electronic device developed using this closed-loop recycling approach.
See Park et al.
Image: CUBE3D Graphic. Cover design: Lauren Heslop.",C,MAC_Bench/Nature/Cover/Nature Electronics/1_5.png,MAC_Bench/Nature/Cover/Nature Electronics/1_5.png,vitg,1_5.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_8.png,MAC_Bench/Nature/Cover/Nature Electronics/7_8.png,ave_1,7_8.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_12.png,MAC_Bench/Nature/Cover/Nature Electronics/7_12.png,groundtruth,7_12.txt,MAC_Bench/Nature/Cover/Nature Electronics/1_3.png,MAC_Bench/Nature/Cover/Nature Electronics/1_3.png,clip,1_3.txt,train
ACS Catalysis,2024_16,Which of the following options best describe the cover story?,The debut of cyclic alkyl amino carbene on the gold nanoparticle surface leads to the selective reduction of CO2 to CO.,A,MAC_Bench/ACS/Cover/ACS Catalysis/2024_16.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_16.png,groundtruth,2024_16.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2011_7.png,MAC_Bench/ACS/Cover/ACS Catalysis/2011_7.png,clip,2011_7.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2015_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2015_11.png,vitg,2015_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_6.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_6.png,ave_2,2024_6.txt,train
Crystal Growth & Design,2024_12,Which of the following options best describe the cover story?,Artistic representation of crystals ranging in size and morphology as they are being dissolved into a stream of flowing fluid. The image was created with the help of the DALL,B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,clip,2017_5.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_12.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_10.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_10.png,vitg,2022_10.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_11.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_11.png,ave_2,2024_11.txt,val
Macromolecules,2024_4,Which of the following options best describe the cover story?,L-Glutamic acid acts as molecular glue connecting αlanine units to produce fluorescent poly-Glu-Ala. View the article.,C,MAC_Bench/ACS/Cover/Macromolecules/2024_14.png,MAC_Bench/ACS/Cover/Macromolecules/2024_14.png,clip,2024_14.txt,MAC_Bench/ACS/Cover/Macromolecules/2011_5.png,MAC_Bench/ACS/Cover/Macromolecules/2011_5.png,vitg,2011_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_4.png,MAC_Bench/ACS/Cover/Macromolecules/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_17.png,MAC_Bench/ACS/Cover/Macromolecules/2012_17.png,vith,2012_17.txt,test
Nature Reviews Endocrinology,21_1,Which of the following options best describe the cover story?,"Mapping progress in cell replacement therapies for T1DM, inspired by the Review on p14.
Cover design: Edward Byrne",C,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_4.png,vith,19_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/21_1.png,groundtruth,21_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_1.png,vitg,20_1.txt,train
Nature Protocols,19_2,Which of the following options best describe the cover story?,"Mice in motion
Animal behavior is built from basic units of movement, analogous to syllables in human language. In mice, these ‘syllables’ have subsecond duration and include rears, turns, darts and more. Pose trajectories for several example syllables are shown here. To help with visualization, consecutive frames have been shifted horizontally before superimposing them. See Lin et al
Image: Caleb Weinreb, Harvard Medical School. Cover design: S. Harris",B,MAC_Bench/Nature/Cover/Nature Protocols/17_3.png,MAC_Bench/Nature/Cover/Nature Protocols/17_3.png,ave_2,17_3.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_2.png,MAC_Bench/Nature/Cover/Nature Protocols/19_2.png,groundtruth,19_2.txt,MAC_Bench/Nature/Cover/Nature Protocols/14_6.png,MAC_Bench/Nature/Cover/Nature Protocols/14_6.png,clip,14_6.txt,MAC_Bench/Nature/Cover/Nature Protocols/14_7.png,MAC_Bench/Nature/Cover/Nature Protocols/14_7.png,vith,14_7.txt,test
Nature Reviews Electrical Engineering,1_7,Which of the following options best describe the cover story?,"Hardware-aware neural architecture search is a useful tool to design efficient in-memory computing hardware for deep-learning accelerators. The cover image highlights a successful combination. SeeKrestinskaya et al.
Cover design: Sam Whitham",A,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,groundtruth,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,ave_2,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,clip,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,ave_3,1_1.txt,val
Trends in Biotechnology,43_2,Which of the following options best describe the cover story?,"Innovators aiming to introduce a new medical device to the market
often face significant challenges with regulatory clearance and reimbursement.
In pages 4 –7 of this issue, Buenz and colleagues provides an overview of these
processes, bridging a crucial gap between device development and patient care.
Cover image created by Jihed Yahyaoui.",B,MAC_Bench/Cell/Cover/Trends in Biotechnology/43_1.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/43_1.png,clip,43_1.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/43_2.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/43_2.png,groundtruth,43_2.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_10.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_10.png,ave_3,36_10.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,vitg,38_12.txt,train
Cell Chemical Biology,31_15,Which of the following options best describe the cover story?,"On the cover: For Cell Chemical Biology’s 30th anniversary year, we kick off our celebrations with a special issue on RNA
modulation alongside an Editorial, a Q&A from founding editors, and other opinion
pieces from RNA biologists presenting opportunities for targeting RNA. The cover illustrates
the adaptability of RNA molecules, which allow natural and synthetic modulation for
expanded functions. This reflects the topics of the Reviews and Articles within the
special issue describing advances in our understanding of the structural diversity,
function, and regulation of RNA and harnessing this knowledge for therapeutic strategies
against viral infections or cancer. Cover art by Phillip Krzeminski.",C,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png,vitg,31_7.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_5.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_5.png,vith,31_5.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_15.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_15.png,groundtruth,31_15.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/23_9.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/23_9.png,clip,23_9.txt,train
Nature Synthesis,4_1,Which of the following options best describe the cover story?,"Anisotropic 2D metals
Elemental metal nanosheets with aligned grain orientations are grown using a confined 2D template, resulting in nanosheets with high in-plane electrical anisotropy. The anisotropic 2D metals are demonstrated as switching elements.
See Kim et al.
Image: Wooyoung Shim, Yonsei University. Cover design: Thomas Phillips",B,MAC_Bench/Nature/Cover/Nature Synthesis/2_5.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_5.png,ave_2,2_5.txt,MAC_Bench/Nature/Cover/Nature Synthesis/4_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/4_1.png,groundtruth,4_1.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_1.png,vitg,2_1.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,clip,3_1.txt,train
NATURE REVIEWS CANCER,24_9,Which of the following options best describe the cover story?,"Black voices, inspired by the Viewpoint on p235.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_12.png,vitg,24_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/15_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/15_10.png,vith,15_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_2.png,clip,24_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_9.png,groundtruth,24_9.txt,train
ACS Materials Letters,2024_11,Which of the following options best describe the cover story?,Density functional theory + machine learning-based approaches are used to screen out suitable cathode hosts from a large number of MXenes for the optimum adsorption of possible intermediates in aluminum–sulfur batteries. AI was used partially in the creation of this cover graphic.,D,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_3.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_3.png,vith,2019_3.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_5.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_4.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_11.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_11.png,groundtruth,2024_11.txt,train
Trends in Chemistry,6_2,Which of the following options best describe the cover story?,"BURP domain peptide cyclases (BpCs) represent a newly emerging class
of copper enzymes that catalyze the oxidative macrocyclization of peptides in plants,
offering exciting potential for advances in plant biochemistry and biotechnology.
In their
Opinion article, Hematian and Noyon discuss the recent breakthroughs in understanding
the sequence, structure, and function of BpCs, along with their proposed chemistry.
They offer potential mechanistic models and highlight critical structural aspects
that
could guide future research into BpCs' reactivity and catalytic mechanisms. Artwork
credit: Shabnam Hematian & M. Rafi ul O. K. Noyon",D,MAC_Bench/Cell/Cover/Trends in Chemistry/5_12.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_12.png,vitg,5_12.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/4_3.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_3.png,clip,4_3.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/3_3.png,MAC_Bench/Cell/Cover/Trends in Chemistry/3_3.png,vith,3_3.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_2.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_2.png,groundtruth,6_2.txt,train
Journal of Chemical Theory and Computation,2024_2,Which of the following options best describe the cover story?,"Scanning the PDB and using QM calculations on the MP2/TZVPP level of theory, we highlight the geometric versatility and potential benefits of halogen–water interactions, trying to assess whether halogen bonding on water is more than a “drop in the ocean” for drug discovery.",A,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_21.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_21.png,clip,2024_21.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_22.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_22.png,vith,2023_22.txt,train
NATURE IMMUNOLOGY,26_1,Which of the following options best describe the cover story?,"Predicting longevity of antibody responses
The turtle is a timeless symbol of longevity in Aboriginal and Native American cultures, soaring through the sky. Within its form, one can see multinucleated megakaryocytes and plasma cells, vital components of the longevity of the immune response induced by vaccination. This visual encapsulates the key findings of the Article, illustrating how vaccination stimulates immune cells that sustain durable antibody responses.
See Cortese et al.
Image: Michael David Ferguson, Yale University; Concept by Bali Pulendran, Stanford University. Cover design: Vanitha Selvarajan",A,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/26_1.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/26_1.png,groundtruth,26_1.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/26_2.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/26_2.png,clip,26_2.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/20_4.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/20_4.png,vitg,20_4.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_6.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_6.png,ave_2,11_6.txt,train
Developmental Cell,59_8,Which of the following options best describe the cover story?,"On the cover: The cover features three overlaid images of rice seed embryos during
germination using three methodologies: cell wall staining image generated during Stereo-seq
sequencing (lower, white image); automatic cell segmentation using a self-trained
model (middle, colored image); in situ spatial gene expression map of the rice embryo achieved through cell segmentation
(top, colored image), with the same colors representing cells identified as the same
cluster in unsupervised learning. The design of the cover image highlights the crucial
data production stages in our article. To learn more about the spatiotemporal transcriptome
of the rice embryo and the roles of different cell types in seed germination, see
Yao et al. Image credit: Jie Yao and Longjiang Fan.",B,MAC_Bench/Cell/Cover/Developmental Cell/38_6.png,MAC_Bench/Cell/Cover/Developmental Cell/38_6.png,vith,38_6.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_8.png,MAC_Bench/Cell/Cover/Developmental Cell/59_8.png,groundtruth,59_8.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,MAC_Bench/Cell/Cover/Developmental Cell/59_20.png,vitg,59_20.txt,MAC_Bench/Cell/Cover/Developmental Cell/29_6.png,MAC_Bench/Cell/Cover/Developmental Cell/29_6.png,clip,29_6.txt,train
Nature Cities,1_2,Which of the following options best describe the cover story?,"The potential of city rooftops
Rooftops have space to accommodate photovoltaic panels and urban agriculture interventions, which could have consequences for energy consumption, heat regulation and economic wellbeing. Studies by Yang et al., Simpson et al. and Khan et al. show this potential, and unexpected tradeoffs.
See Yang et al. , Simpson et al. and Khan et al.
Image: GlobalVision Communication/GlobalVision 360/Moment/Getty. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,ave_2,1_5.txt,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,groundtruth,1_2.txt,MAC_Bench/Nature/Cover/Nature Cities/1_10.png,MAC_Bench/Nature/Cover/Nature Cities/1_10.png,vith,1_10.txt,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,clip,1_7.txt,train
Trends in Cell Biology,34_9,Which of the following options best describe the cover story?,"Cell-cell interactions are integral to countless biological processes in the
human body, and artificial control of these interactions would enable advances in
basic
research and therapeutic engineering. Researchers have previously overexpressed
endogenous membrane proteins to induce affinity, which tends to have cross-affinity
and trigger unintended signaling. Several engineered methods, from chemical-based
to peptide-based methods, have recently become available to program intercellular
interactions. On pages 277–287 in this issue, Chao et al., the creators of helixCAM,
discuss where the state of the art is for this growing field, along with key areas
of
development. Additionally, they present potential use cases across developmental
biology, immunology, and neuroscience to encourage scientists to experiment with
and incorporate the ability to control cell-cell interactions into constructing their
model systems.Cover design by Kathryn Kamowski.",B,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_9.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_9.png,vith,26_9.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_9.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_9.png,groundtruth,34_9.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_11.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_11.png,vitg,29_11.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_2.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/29_2.png,clip,29_2.txt,train
Nano Letters,2025_9,Which of the following options best describe the cover story?,"The cover art depicts a microtubule structure with intact and open segments exposing the inner surface. Atomic force microscopy reveals a high-resolution view, showing an undulating arrangement of protofilaments (PFs) with alternating height variations, caused by different structural orientations and conformations of αβ-tubulin dimers in adjacent PFs. View the article.",A,MAC_Bench/ACS/Cover/Nano Letters/2025_9.png,MAC_Bench/ACS/Cover/Nano Letters/2025_9.png,groundtruth,2025_9.txt,MAC_Bench/ACS/Cover/Nano Letters/2015_2.png,MAC_Bench/ACS/Cover/Nano Letters/2015_2.png,vith,2015_2.txt,MAC_Bench/ACS/Cover/Nano Letters/2015_5.png,MAC_Bench/ACS/Cover/Nano Letters/2015_5.png,ave_0,2015_5.txt,MAC_Bench/ACS/Cover/Nano Letters/2023_3.png,MAC_Bench/ACS/Cover/Nano Letters/2023_3.png,clip,2023_3.txt,train
Nature Chemical Biology,20_12,Which of the following options best describe the cover story?,"Living with lipid mimics
Genetic code expansion (GCE) techniques are valuable for studying post-translational modifications by incorporating modified non-canonical amino acids into specific sites within target proteins. The image depicts lipidated proteins produced via GCE anchored to the membrane.
See Ding et al.
Image credit: Wenlong Ding and Chao Liu, Zhejiang University. Cover design: Alex Wing",B,MAC_Bench/Nature/Cover/Nature Chemical Biology/19_12.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/19_12.png,vitg,19_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_12.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_12.png,groundtruth,20_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,vith,17_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/16_1.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/16_1.png,clip,16_1.txt,test
Nature Water,2_8,Which of the following options best describe the cover story?,"Degrading pollution of degrading tires
Emerging pollutants in water are getting attention due to their adverse health impacts. Given their widespread presence and harmful characteristics, effective treatment methods like degradation and filtration are essential. Advanced oxidation processes (AOPs) hold the potential to achieve effective degradation or even mineralization of organic pollutants, owing to the active involvement of radicals. Long Chen and colleagues have now designed a periodate-based AOP tailored for the degradation of the contaminant 6PPD-quinone — a recently identified pollutant originating from rubber tires — at environmentally relevant concentrations. The cover illustrates the concept of water pollution caused by the degradation of rubber tires.
See Chen et al.
Image: Agentur-kroeger/iStock/Getty Images Plus/Getty. Cover design: Valentina Monaco",C,MAC_Bench/Nature/Cover/Nature Water/1_11.png,MAC_Bench/Nature/Cover/Nature Water/1_11.png,vith,1_11.txt,MAC_Bench/Nature/Cover/Nature Water/1_8.png,MAC_Bench/Nature/Cover/Nature Water/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Water/2_8.png,MAC_Bench/Nature/Cover/Nature Water/2_8.png,groundtruth,2_8.txt,MAC_Bench/Nature/Cover/Nature Water/1_7.png,MAC_Bench/Nature/Cover/Nature Water/1_7.png,clip,1_7.txt,train
Trends in Endocrinology & Metabolism,35_12,Which of the following options best describe the cover story?,"Aging clocks, computational models that measure biological age
and aging rate regardless of the chronological age, are important tools to study the
mechanisms of healthy longevity. However, the underlying counting units of the intrinsic
timers of these clocks are still unclear. This month, Han (pp. 11−22) proposes that
DNA damage and its associated response constitute the fundamental counting units
of aging clocks, ultimately responsible for changes in cell cycles, cellular senescence,
and functional decline in tissues. The cover represents the multiple levels of “ticking
components” of aging clocks. Cover credit: adapted from ziggymaj/Getty Images.",A,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_12.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_12.png,groundtruth,35_12.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_2.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_2.png,vith,25_2.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/34_10.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/34_10.png,clip,34_10.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_9.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_9.png,ave_1,30_9.txt,test
Trends in Cognitive Sciences,28_5,Which of the following options best describe the cover story?,"The motivations to protect oneself and others are often seen as
conflicting. In this issue of Trends in Cognitive Sciences, Joana B. Vieira and Andreas
Olsson draw on recent animal and human research to challenge the belief that self-preservation
must be suppressed to care for others. They suggest that neuroendocrine
mechanisms involved in individual defense are, in fact, essential for protecting others.
By reconceptualizing defense and care as convergent processes, this framework
opens new research avenues, including examining how defensive mechanisms
influence prosocial behaviors and how caregiving experiences affect defensive
tendencies in humans. Cover depicts a female Tana River mangabey and her infant.
Cover image from Anup Shah/Getty Images.",A,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_5.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_5.png,groundtruth,28_5.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/19_12.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/19_12.png,vith,19_12.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_10.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_10.png,clip,18_10.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/19_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/19_1.png,vitg,19_1.txt,train
Trends in Parasitology,40_5,Which of the following options best describe the cover story?,"In this issue of Trends in Parasitology, Darif et al. report on the recent
20th BioMalPar, a world-leading conference on the biology and pathology of malaria
parasites. Frischknecht et al. reflect on what has been achieved in the last 20 years
through the European Union Network of Excellences (NoEs) BioMalPar and EviMalaR as
well as other pan-European networks, provide examples of specific achievements, and
look to the future. The cover shows a cartoon from the malaria comic of the EviMalaR
NoE (https://www.gla.ac.uk/research/az/wcip/engage/publicengagement/wcipcomics/),
which illustrates the molecular tinkering performed by researchers in these networks
to uncover the unique biology of Plasmodium. The cartoon is surrounded by scanning
electron microscopy images of uninfected red blood cells as well as those infected
with
asexual and sexual stages of Plasmodium falciparum. Image credit: Aurélie Claes, Artur
Scherf, and Edward Ross.",B,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,vitg,34_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_5.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_5.png,groundtruth,40_5.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/28_1.png,MAC_Bench/Cell/Cover/Trends in Parasitology/28_1.png,clip,28_1.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/31_7.png,MAC_Bench/Cell/Cover/Trends in Parasitology/31_7.png,vith,31_7.txt,train
Accounts of Chemical Research,2024_8,Which of the following options best describe the cover story?,"Everything in the world has two sides. Surface engineering of 2D BP can not only show highly durable nanophotonic devices, including optics, optoelectronics, and photocatalysis, but is also capable of constructing excellent biodegradable delivery nanoplatforms in biophotonics, such as photo-assisted cancer therapy.",C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_6.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_6.png,clip,2019_6.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_12.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_12.png,vith,2015_12.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_8.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_17.png,vitg,2021_17.txt,val
Trendsin Neurosciences,47_1,Which of the following options best describe the cover story?,"Retinal ganglion cells and their neural and glial partners are essential
for integrating light-induced signals from the eye and transmitting them to various
brain regions. This information drives vision as well as non-visual brain functions
regulated by light, such as circadian photoentrainment, sleep modulation, alertness,
attention, and mood. However, RGCs can differ considerably across species. In
this issue of Trends in Neurosciences, Kang-Chieh Huang, Mohamed Tawfik, and
Melanie Samuel examine retinal ganglion cell and glial features that are conserved
across mice, humans, and primates, as well as those that vary. They also discuss
experimental approaches for studying human and primate retinal ganglion cells.
The cover image highlights one such approach, showing uman retinal ganglion cells
derived from an embryonic stem cell line, with retinal ganglion cell bodies in green
and axons in magenta. Photo credits: Kang-Chieh Huang and Mohamed Tawfik.",A,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_1.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_1.png,groundtruth,47_1.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,vith,43_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/45_7.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/45_7.png,clip,45_7.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,vitg,47_3.txt,train
Nature Metabolism,6_10,Which of the following options best describe the cover story?,"Bone-to-brain crosstalk
Bone-derived sclerostin accelerates the progression of Alzheimer’s disease (AD) by deregulating the Wnt–β-catenin signalling pathway in the brain. The image is a staining of the enzyme β-secretase (essential for AD pathogenesis) in a hippocampus section from a mouse model of AD.
See Shi et al.
Image: Baosheng Guo, Nanjing University. Cover Design: Thomas Phillips.",D,MAC_Bench/Nature/Cover/Nature Metabolism/1_1.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_5.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_5.png,vith,3_5.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_4.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_4.png,vitg,3_4.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_10.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_10.png,groundtruth,6_10.txt,train
Trends in Cancer,10_2,Which of the following options best describe the cover story?,"It was a long-held notion that cancer cells could only grow if
angiogenesis was induced. However, recent findings have shown that some forms
of cancer can grow in the absence of angiogenesis by exploiting existing vessels.
In this issue, Harris et al. review the mechanisms supporting a revision of one of
the Hallmarks of Cancer from ‘inducing angiogenesis’ to ‘inducing or accessing
the vasculature.’ Cover image design from gettyimages/MARK GARLICK/SCIENCE
PHOTO LIBRARY.",D,MAC_Bench/Cell/Cover/Trends in Cancer/9_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/9_1.png,ave_1,9_1.txt,MAC_Bench/Cell/Cover/Trends in Cancer/3_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_6.png,clip,3_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/1_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/1_1.png,vitg,1_1.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_2.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_2.png,groundtruth,10_2.txt,train
Cell Reports Methods,4_5,Which of the following options best describe the cover story?,"On the cover: In this issue, Poovathingal et al. present Nova-ST, an open-source sequencing-based spatial transcriptomics workflow.
The cover illustrates a spatial imprint of captured transcripts by Nova-ST from the
mouse brain. The illustration below the brain section represents an electron micrograph
of the repurposed Illumina Novaseq sequencing chip. Cover design by Duygu Koldere
Vilain (designosome.com).",D,MAC_Bench/Cell/Cover/Cell Reports Methods/3_1.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_1.png,clip,3_1.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/1_6.png,MAC_Bench/Cell/Cover/Cell Reports Methods/1_6.png,vitg,1_6.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_8.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_8.png,vith,2_8.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_5.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_5.png,groundtruth,4_5.txt,val
Nature Machine Intelligence,6_1,Which of the following options best describe the cover story?,"Learned social interaction patterns
Biomimetic robots can be used to study animal social behaviour. Jia et al. designed an interactive robot and use imitation learning to provide it with subtle templates of social behaviour. Through long-term and repetitive interactions, the robot can modulate the emotional state of rats. The image shows a rat-like robot interacting with a freely behaving rat by expressing complex postures.
See Jia et al.
Image: Qing Shi, Beijing Institute of Technology. Cover design: Vanitha Selvarajan",A,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_1.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_1.png,groundtruth,6_1.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_5.png,vitg,4_5.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_5.png,vith,2_5.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_11.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_11.png,clip,4_11.txt,train
Journal of the American Chemical Society,2024_35,Which of the following options best describe the cover story?,"A lipid-modified poly(guanidine thioctic acid) polymer is developed as a fortifier for lipid nanoparticles with the capability to eliminate reactive oxygen species, greatly improving the translation efficiency and alleviating inflammation of mRNA vaccines. This formulation shows promising potential in the fabrication of next-generation mRNA vaccines and therapeutics.  View the article.",C,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_8.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_8.png,vith,2023_8.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_51.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_51.png,clip,2018_51.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_35.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_35.png,groundtruth,2024_35.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_28.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_28.png,vitg,2023_28.txt,train
ACS Food Science & Technology,2024_2,Which of the following options best describe the cover story?,"Optimizing brewing conditions to enhance probiotic viability in beer: Twenty-one lactic acid bacteria strains with potential probiotic properties were tested for resilience against ethanol and hops, with certain strains thriving in Gueuze-style sour beer. Findings indicate that alternative methods are required to support probiotic viability in hopped beers. This cover image was created using Canva AI.",D,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,ave_2,2023_2.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,vitg,2022_11.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_7.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_2.png,groundtruth,2024_2.txt,test
Nature Structural & Molecular Biology,31_1,Which of the following options best describe the cover story?,"Autoimmune antibodies in the inflamed brain
Two studies by Michalski, Abdulla et al. and Wang, Xie, Deng, Ding, Li et al. provide insights into how antibodies seen in individuals with autoimmune encephalitis interact with and affect the functions of their target, NMDA receptors.
See Michalski, Abdulla et al. and Wang, Xie, Deng, Ding, Li et al.
Image credit: Westend61 / Getty images. Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_2.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_2.png,clip,31_2.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_1.png,groundtruth,31_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/24_9.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/24_9.png,vith,24_9.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,vitg,28_8.txt,train
Inorganic Chemistry,2025_7,Which of the following options best describe the cover story?,"Co-encapsulating ligands can facilitate tunable chemistry by bringing metals together. This cover, depicting a racing circuit, conveys the excitement of clocking both ligand and metal performance. As the associated paper shows, in this chemical race, acyclic ligands and trivalent cations are high performers. The cover was prepared with Adobe Illustrator and MidJourney.",A,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_7.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_34.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_34.png,vitg,2024_34.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_40.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_40.png,ave_2,2024_40.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_27.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_27.png,clip,2023_27.txt,train
Nature Water,2_3,Which of the following options best describe the cover story?,"Towards net zero in the wastewater sector
Wastewater treatment is responsible for a large amount of greenhouse gas emissions, especially methane and nitrous oxide. Accounting for all those emissions is complex because emissions originate from several parts of the process, but it is the first, essential step towards a more sustainable wastewater industry. The Review by Ren and co-authors examines these complexities and provides guidance for the direction to take to eventually achieve net zero emissions. The cover shows a large urban wastewater treatment plant in Hong Kong.
See Song et al.
Image: dragon for real / Moment / Getty Images. Cover design: Debbie Maizels.",C,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Water/1_8.png,MAC_Bench/Nature/Cover/Nature Water/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Water/2_3.png,MAC_Bench/Nature/Cover/Nature Water/2_3.png,groundtruth,2_3.txt,MAC_Bench/Nature/Cover/Nature Water/2_10.png,MAC_Bench/Nature/Cover/Nature Water/2_10.png,vith,2_10.txt,val
iScience,27_2,Which of the following options best describe the cover story?,"On the cover: The illustration represents the interconnectedness of the elements affected
during urban ecosystem rehabilitation plans: the health of the environment and all
living beings, urban architecture, and human psychological perception. In the foreground,
the head symbolizes a “green city” built upon scientific foundations, with intertwined
natural and architectural elements, idealizing a balanced system where micro- and
macrobiomes healthily coexist. In the mirror reflection, invasive species, pathogens,
and pests highlight the challenges that need to be scientifically monitored to prevent
them from becoming negative aspects of the green transition toward the cities of tomorrow.
This vision is the core of the perspective by Bruno et al., providing an evidence-based urban rehabilitation framework. Image credit: Giulia
Ghisleni.",A,MAC_Bench/Cell/Cover/iScience/27_2.png,MAC_Bench/Cell/Cover/iScience/27_2.png,groundtruth,27_2.txt,MAC_Bench/Cell/Cover/iScience/25_1.png,MAC_Bench/Cell/Cover/iScience/25_1.png,clip,25_1.txt,MAC_Bench/Cell/Cover/iScience/26_7.png,MAC_Bench/Cell/Cover/iScience/26_7.png,ave_2,26_7.txt,MAC_Bench/Cell/Cover/iScience/24_7.png,MAC_Bench/Cell/Cover/iScience/24_7.png,vitg,24_7.txt,train
Nature Protocols,19_7,Which of the following options best describe the cover story?,"MXene jeobeon fan
A scanning electron microscopy image of a Ti3C2Tx MXene particle partially exfoliated by high shear mixing and imaged at the Korea Advanced Institute of Science and Technology (KAIST)/National NanoFab Center (NNFC) in Daejeon, South Korea, during a visit from Philadelphia, USA. The fan has close to the 18 ribs commonly found on traditional Korean fans, while the surrounding particles resemble falling cherry blossom petals that bloom throughout South Korea and Philadelphia. See Downes et al.
Image: Marley Downes, A.J. Drexel Nanomaterials Institute. Cover design: S. Whitham",D,MAC_Bench/Nature/Cover/Nature Protocols/18_10.png,MAC_Bench/Nature/Cover/Nature Protocols/18_10.png,clip,18_10.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_7.png,MAC_Bench/Nature/Cover/Nature Protocols/15_7.png,vith,15_7.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,ave_2,19_9.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_7.png,MAC_Bench/Nature/Cover/Nature Protocols/19_7.png,groundtruth,19_7.txt,train
NATURE GENETICS,56_11,Which of the following options best describe the cover story?,"Skin pigmentation diversity in Africans
Characterization of functional variants associated with skin pigmentation in ethnically diverse Africans elucidates their regulatory effect on melanin levels and identifies CYB561A3 as a regulator of pigmentation.
See Feng et al.
Image: Hadynyah/E+/Getty. Cover Design: Tulsi Voralia.",D,MAC_Bench/Nature/Cover/NATURE GENETICS/54_11.png,MAC_Bench/Nature/Cover/NATURE GENETICS/54_11.png,ave_2,54_11.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_4.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_4.png,clip,49_4.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_1.png,vitg,49_1.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_11.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_11.png,groundtruth,56_11.txt,train
Industrial & Engineering Chemistry Research,2024_34,Which of the following options best describe the cover story?,This work presents grafting of a CuCo alloy bimetallic nanoparticle over g-C3N4 for photocatalytic degradation of pharmaceutical contaminant ibuprofen and H2 gas evolution by water splitting.,D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_22.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_22.png,ave_1,2020_22.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_23.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_23.png,clip,2023_23.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,vitg,2024_36.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_34.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_34.png,groundtruth,2024_34.txt,test
Nature Reviews Neurology,20_5,Which of the following options best describe the cover story?,"Neurology in the midnight sun, inspired by the Q&A on p453.
Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/18_2.png,clip,18_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,vitg,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_5.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_5.png,groundtruth,20_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/17_12.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/17_12.png,vith,17_12.txt,test
Journal of Medicinal Chemistry,2024_5,Which of the following options best describe the cover story?,"The image depicts a novel small molecule, PPA24, entering a cancerous cell and binding to the tumor suppressor protein phosphatase 2A to induce its activation and subsequently kill the colon cancer cell through apoptosis. The graphic was created with the assistance of Leonardo.AI. View the article.",D,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_6.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_6.png,vith,2021_6.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_10.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_10.png,vitg,2016_10.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_9.png,clip,2021_9.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_5.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_5.png,groundtruth,2024_5.txt,train
NATURE MATERIALS,24_1,Which of the following options best describe the cover story?,"Electronically morphing microrobot
A kirigami metasheet microrobot shows electronically programmable shape morphing and movement.
See Liu et al.
Image: Zihe Liang and Qingkun Liu, Shanghai Jiao Tong University; Itai Cohen, Cornell University. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/24_1.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/24_1.png,groundtruth,24_1.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/24_2.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/24_2.png,clip,24_2.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/7_6.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/7_6.png,ave_2,7_6.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/18_4.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/18_4.png,ave_3,18_4.txt,train
Industrial & Engineering Chemistry Research,2024_8,Which of the following options best describe the cover story?,A methodology termed “quasi-ternary phase diagram” was devised to serve as a foundation in process design of solvent-mediated physical separation of a multicomponent solid mixture.,D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_10.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_10.png,ave_2,2022_10.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_29.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_29.png,clip,2024_29.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_32.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_32.png,ave_1,2021_32.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_8.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_8.png,groundtruth,2024_8.txt,train
Nature Physics,20_2,Which of the following options best describe the cover story?,"Cellular energy budget
How cells manage the internal energetic budget to drive mechanical and chemical dynamics is still an open question. Sheng Chen and collaborators show that the allocation of energy depends on how far the cell is from thermodynamic equilibrium.
See Sheng Chen et al.
Image: William Bement (University of Wisconsin-Madison), Sheng Chen (Yale University), Michael Murrell (Yale University). Cover design: Laoise Mac Gabhann",A,MAC_Bench/Nature/Cover/Nature Physics/20_2.png,MAC_Bench/Nature/Cover/Nature Physics/20_2.png,groundtruth,20_2.txt,MAC_Bench/Nature/Cover/Nature Physics/20_5.png,MAC_Bench/Nature/Cover/Nature Physics/20_5.png,vitg,20_5.txt,MAC_Bench/Nature/Cover/Nature Physics/18_9.png,MAC_Bench/Nature/Cover/Nature Physics/18_9.png,vith,18_9.txt,MAC_Bench/Nature/Cover/Nature Physics/15_3.png,MAC_Bench/Nature/Cover/Nature Physics/15_3.png,clip,15_3.txt,train
Nature Reviews Psychology,3_6,Which of the following options best describe the cover story?,"In this Review, Snyder et al. discuss leading theories of rhythm perception and synthesize relevant behavioural, neural and genetic findings.
Cover design: David Johnston",C,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_5.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_8.png,vith,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_6.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_6.png,groundtruth,3_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_11.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_11.png,vitg,1_11.txt,train
Analytical Chemistry,2025_7,Which of the following options best describe the cover story?,"The inclusive droplet digital ELISA (iddELISA) expands the boundaries of digital immunoassays by incorporating all types of bead encapsulations into the analysis, enhancing assay efficiency, and simplifying operations. This innovative approach holds great promise for the early detection of low-abundance biomarkers.",B,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_22.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_22.png,vitg,2020_22.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_7.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_2.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_2.png,clip,2019_2.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,vith,2022_33.txt,train
Trendsin Neurosciences,47_8,Which of the following options best describe the cover story?,"Human infants undergo rapid and profound changes in behavior and
cognition, yet the underlying brain mechanisms are poorly understood. New methods
for data acquisition and analysis are beginning to reveal the functional development
of the infant brain. In this issue of Trends in Neurosciences, Nick Turk-Browne and
Dick Aslin review these recent advances and provide a road map for the future of infant
brain imaging in humans. The cover image captures several features that characterize
this future, including awake and attentive state, large field of view of naturalistic
stimuli,
and head-mounted sensors. Cover art by Casey Roonan.",B,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_10.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_10.png,vitg,37_10.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_8.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_8.png,groundtruth,47_8.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_12.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_12.png,clip,37_12.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/42_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/42_5.png,vith,42_5.txt,test
Nature Reviews Cardiology,21_8,Which of the following options best describe the cover story?,"Microvascular obstruction in the coronary tree, inspired by the Review on p283.
Cover design: Vicky Summersby",C,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_11.png,vitg,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_8.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_8.png,groundtruth,21_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_8.png,clip,20_8.txt,test
CELL RESEARCH,34_12,Which of the following options best describe the cover story?,"The image shows the tragic story of the Greek soldier Philippides, who brought the victory message of the battle of Marathon to Athens but died after 26 miles and 385 yards (42.195 km) exhaustive running. In fact, human muscle developed mitochondrial protein lactylation as a preventive mechanism for such disaster. See page 13–30 by Yunzi Mao et al. for details.",D,MAC_Bench/Nature/Cover/CELL RESEARCH/34_9.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_9.png,ave_2,34_9.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_6.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_6.png,clip,32_6.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_8.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_8.png,ave_3,32_8.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_12.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_12.png,groundtruth,34_12.txt,train
Nature Microbiology,9_9,Which of the following options best describe the cover story?,"How body-fluid vesicles block viral infection
This image shows fluorescently labelled extracellular vesicles from semen (red) binding to Axl (green), a broadly expressed phosphatidylserine-binding receptor. This interaction interferes with infection by viruses exposing phosphatidylserine to exploit the immunosuppressive uptake mechanism of apoptotic membranes. Given their abundance in semen and saliva, extracellular vesicles may serve as an innate defence against sexual or oral transmission of viruses applying apoptotic mimicry such as Zika, Chikungunya or Ebola.
See Groß et al.
Credit: Hanna Reßin, Institute of Molecular Virology, Ulm University Medical Center. Cover design: Valentina Monaco.",D,MAC_Bench/Nature/Cover/Nature Microbiology/1_10.png,MAC_Bench/Nature/Cover/Nature Microbiology/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Microbiology/1_6.png,MAC_Bench/Nature/Cover/Nature Microbiology/1_6.png,ave_2,1_6.txt,MAC_Bench/Nature/Cover/Nature Microbiology/1_11.png,MAC_Bench/Nature/Cover/Nature Microbiology/1_11.png,vitg,1_11.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_9.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_9.png,groundtruth,9_9.txt,val
ACS Earth and Space Chemistry,2024_10,Which of the following options best describe the cover story?,This backscattered electron image shows the replacement of CuO of Cu2O via a coupled dissolution and precipitation mechanism. The three embedded images depict the reaction scheme of cuprite dissolution in acetate solution: (a) cuprite dissolution reaction; (b) Cu(I) disproportionation to Cu(II) and native Cu; and (c) tenorite precipitation and acetate decarboxylation reaction.,A,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_11.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_11.png,vith,2024_11.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_9.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_2.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_2.png,ave_3,2022_2.txt,train
ACS Catalysis,2024_5,Which of the following options best describe the cover story?,"We successfully employ readily available oxamic acids as carbamoyl radical precursors to couple with pyridinium salts, selectively introducing the amide group into pyridine architectures. The key innovation lies in the successful integration of an acridinium-based photocatalyst, which enables the formation of amide bonds through a consecutive photoinduced electron transfer process.",A,MAC_Bench/ACS/Cover/ACS Catalysis/2024_5.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2020_7.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_7.png,vith,2020_7.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2013_5.png,MAC_Bench/ACS/Cover/ACS Catalysis/2013_5.png,vitg,2013_5.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2021_7.png,MAC_Bench/ACS/Cover/ACS Catalysis/2021_7.png,clip,2021_7.txt,train
Journal of Medicinal Chemistry,2025_3,Which of the following options best describe the cover story?,"This cover art showcases ZG-2305, a novel inhibitor of FIH, designed to target its tyrosine-flip pocket. ZG-2305 shows potential in improving lipid accumulation and reversing hepatic steatosis, raising a promising strategy for the treatment of obesity and fatty liver diseases. A generative AI tool (Midjourney) was used to create a part of the artwork.",A,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2025_3.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_14.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_14.png,vith,2022_14.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,clip,2010_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_24.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_24.png,vitg,2017_24.txt,train
ACS Synthetic Biology,2024_5,Which of the following options best describe the cover story?,. Co-utilization of type I and type II PTSs facilitates the relocation of the nine-gene limonene biosynthesis pathway by using just three expression cassettes. Dual-regulation in peroxisome and cytoplasm is achieved and employed for enhancing,C,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_12.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_12.png,vitg,2024_12.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_5.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,clip,2025_2.txt,train
Lab Animal,53_7,Which of the following options best describe the cover story?,"Effect of housing temperature on gut motility
A growing body of evidence suggests that housing mice at 22°C induces chronic cold stress in the animals. In a new Article, Han et al. show that mice raised at 22°C display faster gut transit than mice raised at 30°C, due to increased stress signals. These results further highlight the influence of environmental factors on mouse biology, which can affect experimental reproducibility.
See Monack et al.
Cover image: Marina Spence. Cover design: Marina Spence.",C,MAC_Bench/Nature/Cover/Lab Animal/52_10.png,MAC_Bench/Nature/Cover/Lab Animal/52_10.png,vitg,52_10.txt,MAC_Bench/Nature/Cover/Lab Animal/52_2.png,MAC_Bench/Nature/Cover/Lab Animal/52_2.png,clip,52_2.txt,MAC_Bench/Nature/Cover/Lab Animal/53_7.png,MAC_Bench/Nature/Cover/Lab Animal/53_7.png,groundtruth,53_7.txt,MAC_Bench/Nature/Cover/Lab Animal/52_7.png,MAC_Bench/Nature/Cover/Lab Animal/52_7.png,vith,52_7.txt,test
ACS Engineering Au,2024_2,Which of the following options best describe the cover story?,"rinciple describes reversible processes, whereas the depolymerization of step-growth polymers involves driving the equilibrium toward the monomer side. Interpreting",C,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_2.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_2.png,clip,2021_2.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2023_2.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2023_2.png,ave_3,2023_2.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_1.png,vith,2021_1.txt,test
Organic Letters,2025_1,Which of the following options best describe the cover story?,"This cover art illustrates the KOtBu-promoted [3 + 2] cycloaddition of DMSO with C60, followed by a one-pot protonation to synthesize 1,2,3,4-cyclic sulfoxide-fused [60]fullerene dihydride. The X-ray crystal structure of this C60 derivative exhibits a round, paper-lantern-like shape, with cyclic sulfoxide outside the C60 cage resembling the handle of the lantern. This [3 + 2] cycloaddition reaction is also applicable to C70, and the lantern-shaped 1,2,3,4-cyclic sulfoxide-fused [60]/[70]fullerene dihydrides can serve as a versatile platform for the site-selective preparation of various fullerene multi-adducts containing a wide range of functional groups. This cover art was designed by Fei Li.",D,MAC_Bench/ACS/Cover/Organic Letters/2024_14.png,MAC_Bench/ACS/Cover/Organic Letters/2024_14.png,vith,2024_14.txt,MAC_Bench/ACS/Cover/Organic Letters/2021_13.png,MAC_Bench/ACS/Cover/Organic Letters/2021_13.png,vitg,2021_13.txt,MAC_Bench/ACS/Cover/Organic Letters/2022_22.png,MAC_Bench/ACS/Cover/Organic Letters/2022_22.png,clip,2022_22.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_1.png,MAC_Bench/ACS/Cover/Organic Letters/2025_1.png,groundtruth,2025_1.txt,train
Environmental Science & Technology,2025_4,Which of the following options best describe the cover story?,This cover art showcases efforts to monitor CO2 emissions through the effective integration of multiple satellite measurements. It highlights an independent method for tracking progress in climate change mitigation.,C,MAC_Bench/ACS/Cover/Environmental Science & Technology/2019_10.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2019_10.png,ave_1,2019_10.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2015_5.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2015_5.png,clip,2015_5.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_4.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_5.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_5.png,ave_2,2025_5.txt,train
Molecular Plant,17_8,Which of the following options best describe the cover story?,"On the cover: Forest trees, serving as foundational components of terrestrial ecosystems, play
a crucial and leading role in combating and mitigating the adverse effects of extreme
climate events. The genus Populus is among the world’s most widely distributed and cultivated trees and has been firmly
established as the primary model system of forest tree species. Despite their ecological
and economic importance, relatively few studies have examined the underlying mechanisms
and connections between genome evolution and adaptive innovations within the genus.
The cover image illustrates the utilization of pan-genomic data (through virtual DNA-like
routes) as navigational maps to discover and explore the “New World” of genomic variations
at the genus level, and to facilitate precise examination of the evolution of genomic
landscape that underpins the remarkable environmental adaptability and phenotypic
diversity of poplar species across diverse continents, climates, and habitats. Image
by Xinyue Hu, Mengke Yu, Tingting Shi and Jing Wang.",D,MAC_Bench/Cell/Cover/Molecular Plant/13_9.png,MAC_Bench/Cell/Cover/Molecular Plant/13_9.png,ave_0,13_9.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_12.png,MAC_Bench/Cell/Cover/Molecular Plant/17_12.png,vitg,17_12.txt,MAC_Bench/Cell/Cover/Molecular Plant/11_11.png,MAC_Bench/Cell/Cover/Molecular Plant/11_11.png,clip,11_11.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_8.png,MAC_Bench/Cell/Cover/Molecular Plant/17_8.png,groundtruth,17_8.txt,val
Nature Metabolism,6_4,Which of the following options best describe the cover story?,"Spatial lipid fluxes
13C-SpaceM combines stable isotope tracing with imaging mass spectrometry thus enabling spatial analysis of lipid dynamics with near single-cell resolution in tissues. The illustration is a photo of a cross-stitch embroidery with a part of the imaging mass spectrometry heatmap used as a scheme. Loose threads outside of the hoop symbolize the metabolic fluxes studied in this manuscript.
See Buglakova et al.
Image: Elena Buglakova, EMBL (embroidery); Massimo Del Prete, EMBL (photo). Cover design: Thomas Phillips",C,MAC_Bench/Nature/Cover/Nature Metabolism/1_6.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Metabolism/1_2.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_4.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_4.png,groundtruth,6_4.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_11.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_11.png,vith,6_11.txt,train
ACS Infectious Diseases,2024_11,Which of the following options best describe the cover story?,"the molecular diversity of glycans present in fungal capsules. We report on the mapping of several antibody epitopes that target the polysaccharide capsule of Cryptococcus neoformans glucuronoxylomannan (GXM). The accompanying fluorescence microscopy image depicts two antibodies, 13F1 (red) and 18B7 (green), binding to distinct regions of the capsule..",C,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2017_2.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2017_2.png,ave_3,2017_2.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2022_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2022_7.png,clip,2022_7.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_11.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_7.png,vitg,2018_7.txt,train
Trends in Plant Science,29_4,Which of the following options best describe the cover story?,"Most high-yielding crops are susceptible to abiotic and biotic stresses,
making them vulnerable to potential effects of climate change. A possible alternative
is
to accelerate the domestication of wild plants tolerant to harsh conditions and enhancing
their yields. However, competition between wild progenitors and newly domesticated
plants may reduce yields. To address this, Pedro M.P. Correia, Javad Najafi, and Michael
Palmgren propose using gene-editing to introduce traits into de novo domesticated
crops and make them visually distinct for weeding robots. By precise editing of key
genes for architectural traits and pigment accumulation, the plants' colors can be
altered. Manipulating these pivotal genes would significantly enhance the accuracy
of
discriminating between newly domesticated crops and their wild counterparts. Advanced
weeding robots could then be trained through machine learning methods to recognize
such signature traits. Image credit: Vibha Duraikkannan.",A,MAC_Bench/Cell/Cover/Trends in Plant Science/29_4.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_4.png,groundtruth,29_4.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/17_3.png,MAC_Bench/Cell/Cover/Trends in Plant Science/17_3.png,clip,17_3.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/23_11.png,MAC_Bench/Cell/Cover/Trends in Plant Science/23_11.png,vith,23_11.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/26_6.png,MAC_Bench/Cell/Cover/Trends in Plant Science/26_6.png,vitg,26_6.txt,train
Nature Aging,4_4,Which of the following options best describe the cover story?,"Oocyte rejuvenation
In this issue, HaiYang Wang et al. show that oocytes from aged mice cultured within follicles from young mice improve their developmental potential. The cover shows reconstituted chimeric follicles in which granulosa cells interact with the oocyte through transzonal projections.
See Wang et al.
Image: HaiYang Wang, National University of Singapore. Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Aging/3_6.png,MAC_Bench/Nature/Cover/Nature Aging/3_6.png,ave_3,3_6.txt,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,MAC_Bench/Nature/Cover/Nature Aging/1_4.png,vitg,1_4.txt,MAC_Bench/Nature/Cover/Nature Aging/4_4.png,MAC_Bench/Nature/Cover/Nature Aging/4_4.png,groundtruth,4_4.txt,MAC_Bench/Nature/Cover/Nature Aging/3_2.png,MAC_Bench/Nature/Cover/Nature Aging/3_2.png,clip,3_2.txt,val
Trends in Immunology,46_2,Which of the following options best describe the cover story?,"Experiments with particular specific pathogen-free (SPF)-inbred mouse
strains from different laboratories often yield conflicting data due to microbiota
variations
due to housing conditions. On pages 17–28, Rosshart, Bruno, and Schueler present
the option of using natural microbiota from wild mice to outcompete and replace
conventional laboratory SPF murine gut microbiota via co-housing (wildlings). They
propose that this may yield more robust, reproducible, and generalizable mouse data
in biomedical research than other models. Image credit: Ethan Tyler, NIH Division
of
Medical Arts.",A,MAC_Bench/Cell/Cover/Trends in Immunology/46_2.png,MAC_Bench/Cell/Cover/Trends in Immunology/46_2.png,groundtruth,46_2.txt,MAC_Bench/Cell/Cover/Trends in Immunology/34_8.png,MAC_Bench/Cell/Cover/Trends in Immunology/34_8.png,vith,34_8.txt,MAC_Bench/Cell/Cover/Trends in Immunology/31_6.png,MAC_Bench/Cell/Cover/Trends in Immunology/31_6.png,clip,31_6.txt,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,vitg,39_14.txt,train
ACS Energy Letters,2025_2,Which of the following options best describe the cover story?,in situ,C,MAC_Bench/ACS/Cover/ACS Energy Letters/2020_1.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2020_1.png,vith,2020_1.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2017_12.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2017_12.png,clip,2017_12.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2022_2.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2022_2.png,vitg,2022_2.txt,train
Nature Chemical Engineering,1_3,Which of the following options best describe the cover story?,"Flash separation of metals
Metal recycling plays a crucial role in mitigating the shortage of critical metals and reducing reliance on primary mining. However, current liquid hydrometallurgical methods consume substantial amounts of water and chemicals while also generating problematic secondary waste. On the other hand, pyrometallurgical processes are often energy intensive and lack selectivity. Now, James Tour and co-workers report a chlorination process that makes use of direct electric heating for the selective separation of critical metals from electronic waste (denoted as electrothermal chlorination, ETC). The ETC process represents a potential shift in metallurgy that could minimize metal supply-chain shortages. The cover shows a carbon paper heater used for the ETC process during electric heating.
See Deng et al.
Image: Shichen Xu, Rice University. Cover design: Laoise Mac Gabhann.",A,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_3.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_3.png,groundtruth,1_3.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,ave_2,1_9.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,vitg,1_12.txt,train
Cell Reports Methods,4_1,Which of the following options best describe the cover story?,"On the cover: In this issue, Takahashi et al. assemble differentiated hindgut and mesodermal cells to generate organoids that recapitulate
tubular macromorphology of the human intestine in vitro. The cover image depicts the assembled intestinal tubules, with hindgut and mesodermal
cells labeled in green and red, respectively. Image credit: Junichi Takahashi and
Tomohiro Mizutani.",C,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,vith,2_11.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_9.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_9.png,clip,3_9.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_1.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_1.png,groundtruth,4_1.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_11.png,vitg,3_11.txt,test
Trends in Pharmacological Sciences,45_6,Which of the following options best describe the cover story?,"Vsevolod V. Gurevich and Eugenia V. Gurevich discuss the biological
effects of free arrestins and the GPCR-arrestin complex, focusing on the regulation
of arrestin-mediated signaling, both receptor-dependent and -independent. They also
address the therapeutic tools needed to modulate the receptor-independent activity
of free arrestins. The cover image illustrates the structure of bovine arrestin-2
(PDB ID
1G4M, molecule A). In the scaled ball-and-stick model, the polar core's positively
(dark
blue) and negatively (red) charged residues, hydrophobic residues forming the three-element
interaction (yellow), finger loop (magenta), middle loop (dark green), and inter-domain
hinge (red) are depicted. The unresolved C-terminus in the crystal structure
(blue) is shown not to scale. The binding sites for clathrin (light green) and clathrin
adaptor AP2 (purple) on both non-visual arrestins are illustrated on the proximal
and
distal C-terminus, respectively. Additionally, the caspase cleavage sites in arrestin-2
(Asp380, pink ball) and arrestin-3 (Asp366, light blue ball) are highlighted. This
image is
adapted from Figure 2 of Gurevich and Gurevich and was created using DS ViewerPro
6.0 (Dassault Systèmes, San Diego, CA).",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_4.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_4.png,vitg,40_4.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_6.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_6.png,clip,42_6.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_6.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_6.png,groundtruth,45_6.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_10.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_10.png,vith,42_10.txt,train
Cell Metabolism,36_4,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Metabolism, He et al. reveal a protective effect of acetate against metabolic and cognitive impairments
caused by sleep disruption. Inspired by Monet’s famous Water Lilies paintings, a “mitochondrion” boat drifts in a lotus pond full of water lilies (which,
in Chinese, symbolize sleeping beauty in water). Two women sit comfortably in the
boat, enjoying tea with “acetate.” Their relaxed postures and the harmonious atmosphere
suggest that acetate promotes health for individuals suffering from sleep disruption.
Artwork by Kehuitang Art Studio.",A,MAC_Bench/Cell/Cover/Cell Metabolism/36_4.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_4.png,groundtruth,36_4.txt,MAC_Bench/Cell/Cover/Cell Metabolism/28_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/28_2.png,vith,28_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_2.png,vitg,36_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/19_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/19_2.png,clip,19_2.txt,test
Cell Systems,15_12,Which of the following options best describe the cover story?,"On the cover: Illustration of a microbial community. In this issue of Cell Systems, Wang et al. show that optimizing metabolic specialization and versatility of individuals within
a microbial consortium yields a metabolic division of labor configuration with the
highest function. Image credit: Getty Images.",C,MAC_Bench/Cell/Cover/Cell Systems/8_1.png,MAC_Bench/Cell/Cover/Cell Systems/8_1.png,clip,8_1.txt,MAC_Bench/Cell/Cover/Cell Systems/4_5.png,MAC_Bench/Cell/Cover/Cell Systems/4_5.png,vith,4_5.txt,MAC_Bench/Cell/Cover/Cell Systems/15_12.png,MAC_Bench/Cell/Cover/Cell Systems/15_12.png,groundtruth,15_12.txt,MAC_Bench/Cell/Cover/Cell Systems/1_4.png,MAC_Bench/Cell/Cover/Cell Systems/1_4.png,vitg,1_4.txt,train
Bioconjugate Chemistry,2024_7,Which of the following options best describe the cover story?,"Our study introduces an innovative therapeutic approach using advanced ultradeformable particles (UDPs), specifically transethosomes, to deliver silver sulfadiazine (SSD) and vitamin E (VE) for bacterial-infected wound healing. This synergistic method significantly reduces the bacterial burden within the wound microenvironment, offering a promising strategy for addressing complications in skin injuries.",B,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_5.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_5.png,clip,2016_5.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_7.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2017_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2017_2.png,ave_1,2017_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_9.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_9.png,ave_2,2016_9.txt,train
Nature Protocols,19_1,Which of the following options best describe the cover story?,"Creating 3D models of a coastal cliff with the iPhone LiDAR sensor
The iPhone LiDAR sensor is used to generate accurate 3D representations of a coastal cliff. The LiDAR sensor allows the rapid generation of detailed 3D models giving insights into object size, volume and geometry. This enables precise measurements of the cliff erosion processes over time. See Luetzenburg et al.p3520.
Image: Gregor Luetzenburg, Geological Survey of Denmark and Greenland Cover design: S. Harris",D,MAC_Bench/Nature/Cover/Nature Protocols/19_7.png,MAC_Bench/Nature/Cover/Nature Protocols/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/Nature Protocols/17_2.png,MAC_Bench/Nature/Cover/Nature Protocols/17_2.png,vitg,17_2.txt,MAC_Bench/Nature/Cover/Nature Protocols/18_4.png,MAC_Bench/Nature/Cover/Nature Protocols/18_4.png,clip,18_4.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_1.png,MAC_Bench/Nature/Cover/Nature Protocols/19_1.png,groundtruth,19_1.txt,train
Cell Reports Physical Science,5_7,Which of the following options best describe the cover story?,"On the cover: In this issue, Ng et al. demonstrate a self-driving digital twin that is designed to automatically improve
the performance of roll-to-roll printed solar cells using high-throughput, closed-loop
techniques driven by machine learning. This month's cover depicts a robotics-controlled,
high-throughput roll-to-roll printer that prints out solar cells, much like what has
been demonstrated in the paper. The cover was designed by Leonard Ng Wei Tat.",C,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_12.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_12.png,clip,3_12.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_5.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_5.png,vitg,3_5.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_7.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_7.png,groundtruth,5_7.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_1.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_1.png,ave_3,1_1.txt,train
Cell Reports,43_2,Which of the following options best describe the cover story?,"On the cover: Fat Cells in Full Bloom. In homage to Van Gogh's iconic Sunflowers,
Rosiflowers are depicted as mature fat cells with increased ribosomal protein expression
that drives their maturation from heterogeneous progenitor leaves and preadipocyte
buds in the adipose stromal vascular fraction. In this issue, De Siqueira et al. demonstrate that the PPARγ agonist, Rosiglitazone, promotes adipogenesis by stimulating
ribosomal gene expression. Image credit: Demin Lu.",C,MAC_Bench/Cell/Cover/Cell Reports/25_10.png,MAC_Bench/Cell/Cover/Cell Reports/25_10.png,clip,25_10.txt,MAC_Bench/Cell/Cover/Cell Reports/27_9.png,MAC_Bench/Cell/Cover/Cell Reports/27_9.png,vitg,27_9.txt,MAC_Bench/Cell/Cover/Cell Reports/43_2.png,MAC_Bench/Cell/Cover/Cell Reports/43_2.png,groundtruth,43_2.txt,MAC_Bench/Cell/Cover/Cell Reports/29_6.png,MAC_Bench/Cell/Cover/Cell Reports/29_6.png,vith,29_6.txt,train
Industrial & Engineering Chemistry Research,2024_32,Which of the following options best describe the cover story?,"With the assistance of the voltage, the rejection of the optimal membrane for acid fuchsin increased from 36.37% to 99% and the permeance was almost unchanged",D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_19.png,clip,2022_19.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,ave_0,2021_45.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_40.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_40.png,vitg,2018_40.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_32.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_32.png,groundtruth,2024_32.txt,train
ACS Applied Bio Materials,2024_7,Which of the following options best describe the cover story?,"A rapid and reagentless electrochemical biosensor constructed from a DNA aptamer, immobilized onto a gold-working electrode. The aptamer is equipped with a redox probe at its top end, which is brought closer to the electrode surface upon target (CRP) binding, to induce a signal-ON event. This illustration was created using the AI image generator, DALL-E-3.",A,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_7.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_9.png,vith,2023_9.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2021_11.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2021_11.png,clip,2021_11.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_5.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_5.png,vitg,2020_5.txt,train
Trends in Immunology,45_6,Which of the following options best describe the cover story?,"VAV1 is a positive regulator of TCR activation and cytokine production in
primary human CD4+ and CD8+ T cells. Loss/suppression of VAV1 can mitigate disease
phenotypes in arthritis, experimental autoimmune encephalomyelitis, or colitis mouse
models. On pages 580–596, Neurath and Berg suggest that targeting VAV1 may hold
therapeutic potential in T and T/B cell-mediated autoimmune and chronic inflammatory
diseases. The illustration represents the battle that unfolds between a dragon destroying
a city (host), and a knight. The scene symbolizes self-reactive T cells (dragon) in
autoimmunity, inflammation (flames), and the potential of drug targeting (knight),
in this
case VAV1. Image credit: Darrison Haftarczyk.",D,MAC_Bench/Cell/Cover/Trends in Immunology/35_1.png,MAC_Bench/Cell/Cover/Trends in Immunology/35_1.png,vith,35_1.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_7.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_7.png,vitg,36_7.txt,MAC_Bench/Cell/Cover/Trends in Immunology/38_13.png,MAC_Bench/Cell/Cover/Trends in Immunology/38_13.png,clip,38_13.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_6.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_6.png,groundtruth,45_6.txt,test
Crystal Growth & Design,2024_8,Which of the following options best describe the cover story?,"What has carbamazepine taught crystal engineers? Crystal engineers acknowledge and appreciate the rich solid form landscape that carbamazepine has to offer and the fundamental questions that it answers, thanks to the time, money, and dedication of numerous pharmaceutical researchers worldwide. The image was partly generated by AI.",C,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_8.png,clip,2022_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_7.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_7.png,vitg,2016_7.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_10.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_10.png,vith,2022_10.txt,train
Nature Chemical Engineering,1_1,Which of the following options best describe the cover story?,"Springing into action
Preventing freezing droplet accretion on surfaces is of practical importance, yet challenging. Now, Zuankai Wang and co-workers report a rationally designed structured elastic surface with spring-like pillars and wetting contrast, which can leverage the water volume expansion during the freezing process to drive the spontaneous ejection of freezing water droplets, irrespective of their impacting locations. The cover image shows a render of two ice droplets on the structured elastic surface, one of which has been ejected from a spring that was compressed temporarily due to freezing.
See Zhang et al.
Image: Hangzhou Sphere Ltd. Cover design: Laoise Mac Gabhann",A,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_1.png,groundtruth,1_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,vith,1_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,vitg,1_6.txt,test
innovation,5_2,Which of the following options best describe the cover story?,"On the cover: In the Mozi Gongshu from the Spring and Autumn and Warring States Periods of ancient China, the principle
of “Shu attacks and Mo defends” is recorded, which means that for every attack strategy,
there is inevitably a corresponding method of defense. This wisdom is vividly reflected
in crop protection of modern agricultural practices. To prevent agricultural pests
from damaging crops, people extensively adopt Bacillus thuringiensis (Bt)-based bioinsecticides and insect-resistant crops. However, the global notorious
pest, Plutella xylostella, utilizes its strong immune system to form a midgut transcriptional regulatory loop
as a “defensive shield” to resist Bt toxicity. The arms race between insect pests
and Bt perfectly exemplifies the ancient “Shu attacks and Mo defends” principle. In
the future, deciphering the “Bt resistance shield” of insect pests can be utilized
to design specific methods to break the evolutionary balance of pest resistance, which
could be conducive to developing novel pest management strategies. This will advance
global crop protection level to new horizons and make a significant contribution to
ensuring food security.",A,MAC_Bench/Cell/Cover/innovation/5_2.png,MAC_Bench/Cell/Cover/innovation/5_2.png,groundtruth,5_2.txt,MAC_Bench/Cell/Cover/innovation/5_1.png,MAC_Bench/Cell/Cover/innovation/5_1.png,clip,5_1.txt,MAC_Bench/Cell/Cover/innovation/5_6.png,MAC_Bench/Cell/Cover/innovation/5_6.png,ave_3,5_6.txt,MAC_Bench/Cell/Cover/innovation/4_2.png,MAC_Bench/Cell/Cover/innovation/4_2.png,vith,4_2.txt,train
Nature Protocols,20_2,Which of the following options best describe the cover story?,"Nanoplastics in plant roots
Transmission electron microscopy image (pseudo-color) showing nanoplastics localized near the catheters of Arabidopsis thaliana roots. Nanoplastics appear in white, the cell wall is depicted in green and the cell is highlighted in gold. See Sun et al.
Image: Xian-Zheng Yuan, Shandong University. Cover design: S. Harris",C,MAC_Bench/Nature/Cover/Nature Protocols/19_7.png,MAC_Bench/Nature/Cover/Nature Protocols/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_7.png,MAC_Bench/Nature/Cover/Nature Protocols/15_7.png,vitg,15_7.txt,MAC_Bench/Nature/Cover/Nature Protocols/20_2.png,MAC_Bench/Nature/Cover/Nature Protocols/20_2.png,groundtruth,20_2.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_3.png,MAC_Bench/Nature/Cover/Nature Protocols/19_3.png,clip,19_3.txt,train
ACS Sensors,2024_6,Which of the following options best describe the cover story?,The cover is a visualization of advancing nucleic acid quantification technology based one-pot CRISPR and RPA reaction systems. The dynamic reaction balance between the two systems can be tuned to unlock quantification capacities of nucleic acid targets from various microbes.,C,MAC_Bench/ACS/Cover/ACS Sensors/2019_12.png,MAC_Bench/ACS/Cover/ACS Sensors/2019_12.png,clip,2019_12.txt,MAC_Bench/ACS/Cover/ACS Sensors/2016_8.png,MAC_Bench/ACS/Cover/ACS Sensors/2016_8.png,vitg,2016_8.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_6.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Sensors/2018_6.png,MAC_Bench/ACS/Cover/ACS Sensors/2018_6.png,ave_3,2018_6.txt,train
iScience,27_5,Which of the following options best describe the cover story?,"On the cover: This image is a representation of the work by Jones et al. at the University of Birmingham, uncovering the mechanism of replisome disassembly
in human cells. Key to DNA replication is the MCM2-7 ring helicase complex, which
promotes DNA unwinding and is thus the main focus of the image. Upon DNA replication
termination, the ubiquitin ligase CUL2-LRR1 forms chains of ubiquitin (black circles)
on MCM7. CUL2-LRR1 has an elongated structure and is shown beneath the MCM2-7 ring,
representing branches of a tree at the forefront. The ubiquitin chains are subsequently
recognized by the unfoldase complex, p97, which is seen at the bottom right of the
image, slightly out of view, and resembles a treetop. Finally, we have included the
most iconic building of our campus in this image, the free-standing clock tower, Old
Joe. Many University events have been held around Old Joe, including fairs; hence,
the MCM2-7 ring complex here resembles one of the most celebrated fairground rides,
the Ferris Wheel. Image credit: Agnieszka Gambus.",B,MAC_Bench/Cell/Cover/iScience/25_9.png,MAC_Bench/Cell/Cover/iScience/25_9.png,vith,25_9.txt,MAC_Bench/Cell/Cover/iScience/27_5.png,MAC_Bench/Cell/Cover/iScience/27_5.png,groundtruth,27_5.txt,MAC_Bench/Cell/Cover/iScience/22_1.png,MAC_Bench/Cell/Cover/iScience/22_1.png,clip,22_1.txt,MAC_Bench/Cell/Cover/iScience/10_1.png,MAC_Bench/Cell/Cover/iScience/10_1.png,vitg,10_1.txt,test
Nature Ecology & Evolution,8_1,Which of the following options best describe the cover story?,"Extreme bottlenecks
In the 19th century, commercial hunters nearly drove the northern elephant seal to extinction. A combination of population genetics, veterinary pathology data, demographic modelling, whole-genome resequencing and genetic simulations suggests that this extreme population bottleneck probably purged much of this species’ genetic load, affecting post-bottleneck population dynamics and contemporary fitness variation.
See Joseph I. Hoffman et al.
Image: Martin Stoffel, Turing Institute, UK. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_8.png,ave_2,2_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/7_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/7_8.png,ave_3,7_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_1.png,groundtruth,8_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_5.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_5.png,clip,4_5.txt,train
NATURE REVIEWS MICROBIOLOGY,23_2,Which of the following options best describe the cover story?,"Harnessing the microbiome for sustainable crop production, inspired by the Review on p9
Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_2.png,vith,19_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/23_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/23_2.png,groundtruth,23_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_8.png,vitg,14_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/23_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/23_1.png,clip,23_1.txt,test
Trends in Microbiology,32_7,Which of the following options best describe the cover story?,"Nitrogen (N) is absolutely essential to life as we know it. Though
atmospherically abundant, N must first be converted, or “fixed,” prior to biological
uptake
and crop fertilizer manufacturing. Synthetic N-fixation, today responsible for half
of all fixed
N, comes with profound economic and environmental costs. Fortunately, an alternative,
ancient biological strategy—catalyzed by microbially hosted nitrogenase proteins—holds
enormous bioengineering potential for sustainable N-fixation. Yet, researchers have
been
unable to mimic this elegant biological solution and lack an understanding of environmental
drivers in its evolution, limiting predictions for how biological N-fixation will
respond to a
changing climate. In this special issue, Holly Rucker and Betül Kaçar review the complex
history of nitrogen fixation over billions of years of planetary history.
Image courtesy: Prof. Betül Kaçar, UW-Madison.",C,MAC_Bench/Cell/Cover/Trends in Microbiology/21_1.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_1.png,clip,21_1.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/23_5.png,MAC_Bench/Cell/Cover/Trends in Microbiology/23_5.png,vith,23_5.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_7.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_7.png,groundtruth,32_7.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/19_8.png,MAC_Bench/Cell/Cover/Trends in Microbiology/19_8.png,vitg,19_8.txt,train
One Earth,7_11,Which of the following options best describe the cover story?,"On the cover: Decarbonizing our energy systems is desperately needed to keep the 1.5°C
target within reach. However, a low-carbon energy transition is not necessarily sustainable.
The impacts of low-carbon energy material recovery, manufacture, installation, maintenance,
and decommissioning, as well as energy security and equity challenges must be considered.
A truly sustainable energy transition must benefit both people and the planet, in
the present and the future.",A,MAC_Bench/Cell/Cover/One Earth/7_11.png,MAC_Bench/Cell/Cover/One Earth/7_11.png,groundtruth,7_11.txt,MAC_Bench/Cell/Cover/One Earth/5_10.png,MAC_Bench/Cell/Cover/One Earth/5_10.png,ave_1,5_10.txt,MAC_Bench/Cell/Cover/One Earth/4_10.png,MAC_Bench/Cell/Cover/One Earth/4_10.png,ave_2,4_10.txt,MAC_Bench/Cell/Cover/One Earth/7_8.png,MAC_Bench/Cell/Cover/One Earth/7_8.png,clip,7_8.txt,train
Chemical Research in Toxicology,2025_1,Which of the following options best describe the cover story?,"This cover art illustrates the chemical structures of A-series Novichok nerve agents (A-230, A-232, and A-234) overlaid on a flask with a skull, symbolizing their lethal design as chemical weapons. The image features a hazmat-suited figure, evoking the protective gear used during the 2018 Novichok poisoning investigation in Salisbury, Wiltshire, England. A neuron in the background highlights the nerve agents' primary biological target.",A,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2025_1.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_3.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_3.png,ave_2,2017_3.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,vith,2023_8.txt,train
NATURE MEDICINE,30_7,Which of the following options best describe the cover story?,"Ozone and health
In this issue, Achebak et al. quantify the contributions of both national ozone and imported ozone to the ozone-related mortality burden in 35 European countries, showing that most deaths are attributable to imported ozone. The cover highlights the link between high ozone levels and adverse respiratory health outcomes, and depicts examples of primary ozone sources and transboundary transported ozone.
See Achebak et al.
Image: Mario Ejarque and Albert López, Barcelona Supercomputing Center. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/NATURE MEDICINE/29_9.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/29_9.png,vitg,29_9.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_7.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_7.png,groundtruth,30_7.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/28_7.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/28_7.png,clip,28_7.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_11.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/26_11.png,ave_3,26_11.txt,train
ACS Applied Electronic Materials,2025_2,Which of the following options best describe the cover story?,Two-dimensional (2D) materials-coated paper-based helical origami triboelectric nanogenerators (O-TENGs) are designed to harvest blue energy. The efficient charge transfer between the cellulose and 2D materials significantly improves the output performance of the O-TENGs. This,D,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2021_7.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2021_7.png,vith,2021_7.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2024_5.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2024_5.png,clip,2024_5.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2022_4.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2022_4.png,vitg,2022_4.txt,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Electronic Materials/2025_2.png,groundtruth,2025_2.txt,train
ACS Chemical Biology,2024_3,Which of the following options best describe the cover story?,"Attenuated Listeria monocytogenes (Lmat) is widely tested as an anticancer vaccine. Here, we use click chemistry to functionalize the Lmat cell wall and turn the bacterium into an “intelligent carrier” of the doxorubicin chemotherapeutic drug. Doxorubicin-loaded Lmat",A,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_3.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,vith,2019_9.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2018_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2018_9.png,vitg,2018_9.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2023_6.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2023_6.png,clip,2023_6.txt,train
Developmental Cell,59_18,Which of the following options best describe the cover story?,"On the cover: The image is a graphical representation for the information that can
be obtained from the human liver by a spatial single-cell multi-omic approach. Data
(in blue, water gas cluster ion beam secondary ion mass spectrometry [(H2O)n-GCIB-SIMS] imaging; in red, desorption electrospray ionization mass spectrometry
imaging [DESI-MSI]; and in green, C60-SIMS imaging) identify the metabolic and cellular organization of the liver. To learn
more about how spatial multi-omics provides insight into cell types in the mammalian
liver, see Tian et al. Image credit: Hua Tian and Ella Maru Studio.",D,MAC_Bench/Cell/Cover/Developmental Cell/46_5.png,MAC_Bench/Cell/Cover/Developmental Cell/46_5.png,vitg,46_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/38_2.png,MAC_Bench/Cell/Cover/Developmental Cell/38_2.png,vith,38_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/19_4.png,MAC_Bench/Cell/Cover/Developmental Cell/19_4.png,clip,19_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_18.png,MAC_Bench/Cell/Cover/Developmental Cell/59_18.png,groundtruth,59_18.txt,train
ACS Bio & Med Chem Au,2024_5,Which of the following options best describe the cover story?,"The field-flow fractionation technique enables robust in situ analysis of the biomolecular corona at the surface of nanomedicine, which, in turn, can substantially improve our ability to accurately predict the biological fate of nanomedicine and, therefore, enable development of more effective, safe, and precisely targeted nanomedicine. The image was created by DALL·E.",C,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2023_4.png,vitg,2023_4.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_5.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_5.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_5.png,vith,2022_5.txt,val
ACS Food Science & Technology,2025_2,Which of the following options best describe the cover story?,Purple tomatoes (available in the USA) on a background of red and yellow snaking tomatoes. Photograph Eugenio Butelli and Phil Robison.,C,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,ave_3,2024_10.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2025_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,clip,2023_2.txt,train
Nature Biomedical Engineering,8_9,Which of the following options best describe the cover story?,"Engineering extracellular vesicles to target T cells
This issue highlights intestinal organoids for the analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies, the affinity maturation of mouse B cells reprogrammed to express human antibodies, modular chimaeric cytokine receptors with leucine zippers, engineered extracellular vesicles for targeting T cells and for the delivery of mRNA to neurons, immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells, mesenchymal stromal cells with chimaeric antigen receptors, the generation of antigen-specific mature T cells from engineered stem cells, and engineered heart tissue for the study of metabolic rewiring during tachycardia.
The cover illustrates that extracellular vesicles can be engineered with multiple functionalities for the targeted delivery of biologics to T cells.
See Stranford et al.
Image: Justin Muir. Cover design: Alex Wing.",A,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_9.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_9.png,groundtruth,8_9.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_3.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_3.png,ave_2,8_3.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_12.png,clip,4_12.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_12.png,ave_3,7_12.txt,val
Trends in Pharmacological Sciences,45_8,Which of the following options best describe the cover story?,"Despite the successes in recent years in the development of novel cancer
therapies including small molecule drugs and biologics, resistance to these therapies
is common and affects disease prognosis and quality of life of patients. Towards
eradication of therapy resistance, clinicians and research scientists in different
parts
of the world have leveraged new, advanced technological tools to gain greater insights
of the molecular underpinnings of cancer progression and resistance to treatment.
These insights promise to revolutionize current approaches including drug combination
strategies in tackling therapy resistance in cancer. The June special issue of Trends in
   Pharmacological Sciences features expert perspectives on the recent developments in
the cancer drug resistance field and exciting future avenues of research. Image credit:
Lucidio Studio Inc. via Getty Images Plus.",D,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/37_3.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/37_3.png,ave_0,37_3.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/36_9.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/36_9.png,vith,36_9.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,clip,34_8.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_8.png,groundtruth,45_8.txt,train
NATURE METHODS,21_3,Which of the following options best describe the cover story?,"20 years of Nature Methods
This month, Nature Methods celebrates its 20th anniversary with a special feature.
See Editorial
Image: Thomas Phillips, Springer Nature. Cover design: Thomas Phillips",B,MAC_Bench/Nature/Cover/NATURE METHODS/19_3.png,MAC_Bench/Nature/Cover/NATURE METHODS/19_3.png,clip,19_3.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_3.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_3.png,groundtruth,21_3.txt,MAC_Bench/Nature/Cover/NATURE METHODS/18_12.png,MAC_Bench/Nature/Cover/NATURE METHODS/18_12.png,vith,18_12.txt,MAC_Bench/Nature/Cover/NATURE METHODS/13_1.png,MAC_Bench/Nature/Cover/NATURE METHODS/13_1.png,vitg,13_1.txt,train
ACS Food Science & Technology,2024_12,Which of the following options best describe the cover story?,"The cover art captures the evolution of edible seeds through food processing, illustrating shifts in protein structures as well as water/oil absorption capacities. This visual narrative emphasizes the consequential advancements for edible seeds within the baking industry.",A,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_12.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_8.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_8.png,ave_2,2022_8.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,ave_1,2023_1.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_7.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_7.png,clip,2023_7.txt,train
NATURE REVIEWS NEUROSCIENCE,25_9,Which of the following options best describe the cover story?,"‘Altered activity’, inspired by the Perspective on p272.
Cover design: Jennie Vallis",B,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/22_5.png,vith,22_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_9.png,groundtruth,25_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_7.png,vitg,25_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_10.png,clip,24_10.txt,val
Science Advances,11_7,Which of the following options best describe the cover story?,"ONLINE COVER Habitat and structural home of the fungus-cyanobacterium complex S. cyanobacteriicola-S. taiwanensis. Fungi often form the outer structure in symbiotic relationships such as lichens. However, Chen et al. discovered a symbiosis in Taiwan’s subtropical forests where fungi live within cyanobacterial sheaths, forming erect, nitrogen-fixing thalli. The discovery of the fungus-cyanobacterium complex demonstrates unique fungi residing within structures built by cyanobacteria. This finding sheds light on unique forms of symbiosis and expands our understanding of fungal partnerships in nature. Credit: Che-Chih Chen",B,MAC_Bench/Science/Cover/Science Advances/9_3.png,MAC_Bench/Science/Cover/Science Advances/9_3.png,clip,9_3.txt,MAC_Bench/Science/Cover/Science Advances/11_7.png,MAC_Bench/Science/Cover/Science Advances/11_7.png,groundtruth,11_7.txt,MAC_Bench/Science/Cover/Science Advances/9_34.png,MAC_Bench/Science/Cover/Science Advances/9_34.png,ave_3,9_34.txt,MAC_Bench/Science/Cover/Science Advances/9_30.png,MAC_Bench/Science/Cover/Science Advances/9_30.png,ave_2,9_30.txt,test
Nature Aging,4_11,Which of the following options best describe the cover story?,"Causality-enriched epigenetic clocks
In this issue, Kejun Ying et al. identify CpGs that may be causally linked to aging-related traits using epigenome-wide Mendelian randomization. They develop the epigenetic clocks DamAge and AdaptAge, which track adverse and adaptive outcomes, respectively. The cover image conceptualizes the relationship between DNA methylation and the aging process as a cascade of dominoes that links the youthful individual with the old one. Each domino represents a key CpG site with a causal influence on aging undergoing methylation (denoted by the letter ‘M’). The falling of the dominoes embodies causal effects of these methylation events, suggesting a sequential impact on the progression of aging.
See Ying et al.
Image: Ying Fang, Independent Artist, and Kejun Ying, Harvard University. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,vitg,1_1.txt,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,groundtruth,4_11.txt,MAC_Bench/Nature/Cover/Nature Aging/4_7.png,MAC_Bench/Nature/Cover/Nature Aging/4_7.png,ave_3,4_7.txt,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,clip,4_8.txt,train
ACS Food Science & Technology,2024_7,Which of the following options best describe the cover story?,"The cover art illustrates the dynamic interplay of milk and espresso in the creation of espresso drinks, highlighting the crucial role of this interaction in defining the taste and texture of the beverage. It underlines how advanced two-dimensional infrared spectroscopy experiments can elucidate the complex interactions and dynamics of organic molecules and milk proteins and offer insights into the molecular dance that supports the unique flavor of these popular drinks.",B,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,vith,2024_10.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_7.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,vitg,2023_1.txt,train
Crystal Growth & Design,2024_18,Which of the following options best describe the cover story?,A magnetostructural study has been conducted on two new magnetic 1D coordination polymers with zigzag topology. The front view of the chains resembles an Andean condor,D,MAC_Bench/ACS/Cover/Crystal Growth & Design/2010_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2010_8.png,clip,2010_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_2.png,vith,2016_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_16.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_16.png,vitg,2024_16.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_18.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_18.png,groundtruth,2024_18.txt,train
Cell Stem Cell,31_2,Which of the following options best describe the cover story?,"On the cover: In this issue, two independent studies—Ionescu, Nicaise, et al. and Clayton, Barbar, et al.—use patient-derived brain cells and cellular reprogramming to model multiple sclerosis
(MS). These studies uncover intrinsic disease mechanisms and evaluate potential drug
targets, offering new hope for precise therapies for progressive MS. The image shows
a scientist holding a petri dish with a neuron showing deteriorated myelin, symbolizing
MS, while stem cells float around, highlighting their critical role in potential therapies.
Cover art by DrawImpacts.",B,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,vith,31_3.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_2.png,groundtruth,31_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,vitg,6_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/10_5.png,MAC_Bench/Cell/Cover/Cell Stem Cell/10_5.png,clip,10_5.txt,test
Acta Pharmacologica Sinica,45_3,Which of the following options best describe the cover story?,Cover Credit: CircNSD1 acts as ceRNA of miR-429-3p to promote the target gene SULF1 expression and activate Wnt/β-catenin pathway signaling to enhance fibroblasts proliferation and collagen deposition leading to cardiac fibrosis. (DOI 10.1038/s41401-024-01296-7). See the article in pages 2092-2106.,D,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_9.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_9.png,vith,42_9.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_10.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_10.png,clip,43_10.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_2.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_2.png,vitg,45_2.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_3.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_3.png,groundtruth,45_3.txt,val
Science Robotics,9_96,Which of the following options best describe the cover story?,"ONLINE COVER Perception Through In-Hand Manipulation. Similar to how humans can perceive objects through sight and touch, Suresh et al. constructed a framework that uses data gathered from vision and touch to estimate an object’s pose and shape during manipulation. A dexterous multifingered hand equipped with vision-based touch sensors gathers tactile information while rotating an object. The tactile data, along with visual data from a stationary camera, are input into an online neural field that uses simultaneous localization and mapping to output the geometry of the object. The technique can reconstruct novel objects with high precision, even under heavy occlusion. This month’s cover is an image of a multifingered robot equipped with this framework to perceive the pose and shape of a wooden die. Credit: Sudharshan Suresh",B,MAC_Bench/Science/Cover/Science Robotics/3_19.png,MAC_Bench/Science/Cover/Science Robotics/3_19.png,clip,3_19.txt,MAC_Bench/Science/Cover/Science Robotics/9_96.png,MAC_Bench/Science/Cover/Science Robotics/9_96.png,groundtruth,9_96.txt,MAC_Bench/Science/Cover/Science Robotics/7_67.png,MAC_Bench/Science/Cover/Science Robotics/7_67.png,vitg,7_67.txt,MAC_Bench/Science/Cover/Science Robotics/9_94.png,MAC_Bench/Science/Cover/Science Robotics/9_94.png,vith,9_94.txt,val
Nature Biomedical Engineering,8_6,Which of the following options best describe the cover story?,"Seeking antibiotics in the proteomes of extinct organisms
This issue highlights methods for spatial multi-omics at subcellular resolution, for the mapping of higher-order protein interactions, for studying the functions of non-coding regulatory elements, for interrogating sequence variation in antimicrobial peptides, for antimicrobial-peptide discovery by mining the proteome of extinct organisms, for reinforcing the intestinal mucosal barrier, and for the optogenetic stimulation of vagal nerves, to enhance glucose-stimulated insulin secretion.
The cover illustrates that compounds with antibiotic properties can be discovered by mining, using deep learning, the proteomes of all available extinct organisms.
See Wan et al.
Image: Pix Videos | de la Fuente Lab. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_11.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_11.png,vitg,8_11.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_6.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_6.png,groundtruth,8_6.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_1.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_1.png,ave_0,8_1.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/3_1.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/3_1.png,clip,3_1.txt,val
Nature Climate Change,14_4,Which of the following options best describe the cover story?,"Arctic erosion reduces ocean CO2 sink
Permafrost melting is linked to a number of reinforcing feedback processes accelerating warming. Writing in this issue, Nielsen and colleagues study how increased rates of Arctic coastal erosion, due to permafrost melt, affect Arctic Ocean biogeochemical cycling in an Earth system model. They find that greater terrestrial carbon input limits the amount of atmospheric carbon dioxide that the ocean can sequester, leading to amplified warming.
See Nielsen et al. and News & Views by Manizza
Image: Jenni Schurr and David M. Nielsen. Cover design: Debbie Maizels",C,MAC_Bench/Nature/Cover/Nature Climate Change/9_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/9_10.png,vitg,9_10.txt,MAC_Bench/Nature/Cover/Nature Climate Change/8_1.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_1.png,clip,8_1.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_4.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_4.png,groundtruth,14_4.txt,MAC_Bench/Nature/Cover/Nature Climate Change/8_2.png,MAC_Bench/Nature/Cover/Nature Climate Change/8_2.png,vith,8_2.txt,train
Nature Physics,20_5,Which of the following options best describe the cover story?,"Active holes break multicellular bridges
The formation of holes in epithelial tissue is important for development but can also lead to problems, including cancer, if the process does not work smoothly. Jian-Qing Lv and collaborators have tracked the nucleation, coalescence, and eventual formation of a network of holes in monolayer epithelioid tissues. In particular, they found a fracture–slip mechanism that takes place during hole coalescence and enables the breaking of multicellular bridges without deforming cells too strongly. These results show that the mechanics of living tissues are coordinated across multiple length scales so that holes can form with minimal risk of mechanical damage.
See Jian-Qing Lv et al.
Image: Jian-Qing Lv, Tsinghua University. Cover design: Emily Paul",A,MAC_Bench/Nature/Cover/Nature Physics/20_5.png,MAC_Bench/Nature/Cover/Nature Physics/20_5.png,groundtruth,20_5.txt,MAC_Bench/Nature/Cover/Nature Physics/20_6.png,MAC_Bench/Nature/Cover/Nature Physics/20_6.png,clip,20_6.txt,MAC_Bench/Nature/Cover/Nature Physics/18_9.png,MAC_Bench/Nature/Cover/Nature Physics/18_9.png,vith,18_9.txt,MAC_Bench/Nature/Cover/Nature Physics/17_9.png,MAC_Bench/Nature/Cover/Nature Physics/17_9.png,vitg,17_9.txt,val
Nature Nanotechnology,19_2,Which of the following options best describe the cover story?,"Designer RNA condensates
The cover shows a microscopy image of synthetic cells expressing artificial organelles, assembled from genetically encoded RNA nanostructures.
See Giacomo Fabrini et al.
Image: Giacomo Fabrini (The Francis Crick Institute) and Lorenzo Di Michele (University of Cambridge). Cover design: Vanitha Selvarajan",A,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_2.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_2.png,groundtruth,19_2.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/3_11.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/3_11.png,vitg,3_11.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_12.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_12.png,vith,19_12.txt,train
ACS Measurement Science Au,2022_6,Which of the following options best describe the cover story?,"A prototype smartphone-based device for flow cytometry has been developed, and its operation is facilitated by the use of brightly photoluminescent supra-nanoparticle assemblies of colloidal quantum dots. Cells are immunolabeled with different colors of these assemblies to be classified and enumerated. Cover art by W. Russ Algar.",B,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_6.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_6.png,groundtruth,2022_6.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png,ave_1,2022_2.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,ave_2,2022_1.txt,train
NATURE IMMUNOLOGY,26_2,Which of the following options best describe the cover story?,"Predicting longevity of antibody responses
The turtle is a timeless symbol of longevity in Aboriginal and Native American cultures, soaring through the sky. Within its form, one can see multinucleated megakaryocytes and plasma cells, vital components of the longevity of the immune response induced by vaccination. This visual encapsulates the key findings of the Article, illustrating how vaccination stimulates immune cells that sustain durable antibody responses.
See Cortese et al.
Image: Michael David Ferguson, Yale University; Concept by Bali Pulendran, Stanford University. Cover design: Vanitha Selvarajan",B,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/20_4.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/20_4.png,vitg,20_4.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/26_2.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/26_2.png,groundtruth,26_2.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/26_1.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/26_1.png,clip,26_1.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_6.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_6.png,ave_2,11_6.txt,train
Trends in Biotechnology,42_9,Which of the following options best describe the cover story?,"Molecular engineering of insulin is illustrated by the red color code in the
DNA and further translated to the insulin molecules secreted from the yeast cell in
the
image center. In pages 464–478 of this issue, Kjeldsen and colleagues discuss rational
modification of the insulin structure. This can impact insulin self-association and
folding
stability, which translates to changes in secretory expression yield of critical importance
for industrial application, as illustrated in the bottom left. Cover image from Dr.
Søren
Østergaard, Novo Nordisk A/S.",C,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_6.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/36_6.png,vitg,36_6.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/29_4.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/29_4.png,clip,29_4.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_9.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_9.png,groundtruth,42_9.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_8.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_8.png,vith,38_8.txt,train
Nature Astronomy,8_8,Which of the following options best describe the cover story?,"Warm water cycle reprocesses interstellar matter
The JWST detection of highly excited rotational lines from the hydroxyl radical in an irradiated planet-forming disk indicates an active water cycle in the disk upper layers. This cycle could process the Earth’s oceans’ worth of material in weeks, resetting diagnostic isotope ratios, for instance.
See Zannese et al.
Image: ESA/Webb, NASA, CSA, M. Zamani (ESA/Webb), the PDRs4All ERS Team . Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Astronomy/8_8.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_8.png,groundtruth,8_8.txt,MAC_Bench/Nature/Cover/Nature Astronomy/6_6.png,MAC_Bench/Nature/Cover/Nature Astronomy/6_6.png,vitg,6_6.txt,MAC_Bench/Nature/Cover/Nature Astronomy/7_3.png,MAC_Bench/Nature/Cover/Nature Astronomy/7_3.png,clip,7_3.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_12.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_12.png,vith,8_12.txt,train
Nature Chemistry,16_2,Which of the following options best describe the cover story?,"Climbing the ladder to stable molecular conductance
Advances in single-molecule electronics are crucial for device miniaturization, but achieving stable and controllable conductance in molecular junctions is challenging owing to the dynamic nature of molecular conformations, which fluctuate over operational timescales. Now, Charles Schroeder, Jeffrey Moore, Rajeev Assary, and colleagues have developed a strategy using shape-persistent ladder molecules that maintain nearly junction displacement-independent conductance. The cover illustrates a molecular junction connected by a ladder molecule with a shape-persistent backbone and restricted rotation of terminal anchor groups.
See Liu et al.
Image: Alex Jerez, Beckman Institute at the University of Illinois Urbana-Champaign. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/Nature Chemistry/2_11.png,MAC_Bench/Nature/Cover/Nature Chemistry/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_2.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_2.png,groundtruth,16_2.txt,MAC_Bench/Nature/Cover/Nature Chemistry/2_10.png,MAC_Bench/Nature/Cover/Nature Chemistry/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Chemistry/14_2.png,MAC_Bench/Nature/Cover/Nature Chemistry/14_2.png,ave_2,14_2.txt,train
ACS Food Science & Technology,2024_10,Which of the following options best describe the cover story?,Factors contributing to honey botanical origin and volatile fingerprint: (1),B,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_1.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_1.png,vith,2022_1.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,vitg,2022_11.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_5.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_5.png,clip,2022_5.txt,test
Nature Reviews Cardiology,21_3,Which of the following options best describe the cover story?,"Cardiovascular risk stratification for spaceflight, inspired by the Review on p667.
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_7.png,vith,18_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_3.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_3.png,groundtruth,21_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_4.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/18_4.png,vitg,18_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_1.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_1.png,clip,19_1.txt,test
ACS Biomaterials Science & Engineering,2024_6,Which of the following options best describe the cover story?,"artially oxidized hyaluronic acid was prepared as an adjuvant of a traditional Chinese medicine prescription to treat deep soft tissue injuries. The hydrogel could improve the dosage form of the prescription as well as its antibacterial, antioxidant, and anti-inflammatory properties.",C,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2022_6.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2022_6.png,ave_2,2022_6.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2020_2.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2020_2.png,vith,2020_2.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2024_6.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2020_5.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2020_5.png,clip,2020_5.txt,train
ACS Applied Polymer Materials,2024_21,Which of the following options best describe the cover story?,"This Article focuses on the development of a highly stretchable and self-adhesive wearable biosensor based on nanozyme-catalyzed conductive hydrogels. The authors demonstrate the potential of this biosensor in monitoring electrophysiological signals, such as electromyography (EMG) and electrocardiography (ECG) signals, for applications in rehabilitation training and disease diagnosis.",A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_21.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_21.png,groundtruth,2024_21.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_13.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_13.png,ave_2,2024_13.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_9.png,clip,2023_9.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,ave_3,2025_2.txt,train
ACS Materials Letters,2024_10,Which of the following options best describe the cover story?,"We propose naturally occurring α-quartz crystals as an ideal platform for realizing negative refraction. Quartz forms contact twins sharing a common lattice plane between enantiomorphs with the same or opposite handedness, which can result in phonon surface arcs with open isofrequency contours at the interface between the two enantiomorphs.",C,MAC_Bench/ACS/Cover/ACS Materials Letters/2020_12.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2020_12.png,clip,2020_12.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_12.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_12.png,vitg,2022_12.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_10.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_4.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_4.png,ave_1,2023_4.txt,val
Cell Metabolism,36_8,Which of the following options best describe the cover story?,"On the cover: By developing and applying their Senescence Cell Identification (SenCID)
program to single-cell RNA-seq data, Tao et al. find the stable states of different cell types can erode under persistent stresses
and form trajectories converging toward six senescence endpoints, like a continuum
on the Waddington landscape. They further identified hierarchical modules regulating
the senescence processes through applying SenCID to perturb-seq data. Image by Jing-Dong
J. Han.",C,MAC_Bench/Cell/Cover/Cell Metabolism/26_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/26_2.png,vitg,26_2.txt,MAC_Bench/Cell/Cover/Cell Metabolism/24_1.png,MAC_Bench/Cell/Cover/Cell Metabolism/24_1.png,clip,24_1.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_8.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_8.png,groundtruth,36_8.txt,MAC_Bench/Cell/Cover/Cell Metabolism/12_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/12_3.png,vith,12_3.txt,test
ACS Applied Optical Materials,2024_5,Which of the following options best describe the cover story?,"The authors develop a nonlinear optical imaging technique, which can rapidly visualize hidden interfacial defects in on-chip integrated microdevices. This technique provides a noninvasive means to boost the yield rate of on-chip integrations when being deployed in the production line for in-situ monitoring.",B,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,ave_2,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_5.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,vitg,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_4.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_4.png,clip,2023_4.txt,test
ACS Applied Engineering Materials,2024_7,Which of the following options best describe the cover story?,"Stimuli-responsive luminescent soft materials are of concurrent interest owing to their tunable processability for encryption, sensing, and multimodal security application. Herein, the coordination driven soft gel with lanthanides and a blue-emitting organic linker acts as a trichromic emitter, exhibiting excellent color-rendering efficiency.",A,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_7.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,ave_1,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,vitg,2024_12.txt,test
ACS Applied Polymer Materials,2024_24,Which of the following options best describe the cover story?,Water-soluble spiropyran copolymers retain a photoresponsive feature in response to UV and visible light in pure water. The introduction of a methoxy functional group provides additional binding sites for metal ion complexation.,D,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,vith,2020_12.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_19.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_19.png,clip,2024_19.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_24.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_24.png,groundtruth,2024_24.txt,test
Nature Cancer,5_6,Which of the following options best describe the cover story?,"Mechano-metabolic programming of myeloid cells restricts tumor immunity
TGFβ-induced collagen deposition and metabolic programming of tumor-associated macrophages restricts the anti-tumor activity of CD8+ T cells in the breast cancer microenvironment.
See Tharp et al.
Image: Mary Kate Hayward. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Cancer/4_7.png,MAC_Bench/Nature/Cover/Nature Cancer/4_7.png,clip,4_7.txt,MAC_Bench/Nature/Cover/Nature Cancer/3_9.png,MAC_Bench/Nature/Cover/Nature Cancer/3_9.png,vith,3_9.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_6.png,MAC_Bench/Nature/Cover/Nature Cancer/5_6.png,groundtruth,5_6.txt,MAC_Bench/Nature/Cover/Nature Cancer/1_8.png,MAC_Bench/Nature/Cover/Nature Cancer/1_8.png,vitg,1_8.txt,train
Inorganic Chemistry,2025_5,Which of the following options best describe the cover story?,"Insertion of the alkyl-substituted germylene Ge(FluTMS)2 with germanium halides opens different ways to form Ge–Ge bonds, as shown by the two isolated compounds (FluTMS)2Ge(Cl)GeCl3 and [FluTMSGeCl]4. The reaction with a Ge(I)Br solution is still a complex black-box system that has been slightly uncovered by using germylenes as cluster building blocks and observing their involvement in insertion reactions. The background image was created using Microsoft Designer.",C,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_6.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_6.png,clip,2025_6.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2022_6.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2022_6.png,ave_1,2022_6.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_5.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_35.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_35.png,vitg,2023_35.txt,train
Trends in Endocrinology & Metabolism,35_3,Which of the following options best describe the cover story?,"Mitochondria are multifaceted organelles involved in multi-system
responses. This month’s issue is dedicated to the complexity of mitochondrial
biology from cellular bioenergetics to whole-body physiology, with articles on the
relationship between mitochondrial shape and function (Wai), their interplay with
other
organelles (Lee et al.) their plasticity and function during oocyte development (Bahety
et al.), the role of mitochondrial calcium metabolism in metabolic processes (Huo and
Molkentin), the tissue specificity of mitochondrial diseases (Vela-Sebastián et al.)
and the interdisciplinary efforts needed to elucidate the role of this organelle in
psychobiological processes (Kelly et al.). The cover, a pop-art representation of the
variety of mitochondrial shapes, reflects the breadth of their functions and of the
topics included in this issue. Cover credit: Cover image from Grayson Ticer, VI4 Artist-in-Residence
Program.",B,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_13.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_13.png,clip,26_13.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_3.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_3.png,groundtruth,35_3.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/32_8.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/32_8.png,vith,32_8.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/23_2.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/23_2.png,vitg,23_2.txt,train
Nature Cell Biology,26_8,Which of the following options best describe the cover story?,"Pooled multicolour tagging
Multicolour tagging using intron-targeting single guide RNA libraries and computer vision enables the detection of protein localization changes.
See Reicher et al.
Image: Andreas Reicher, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Cell Biology/13_2.png,MAC_Bench/Nature/Cover/Nature Cell Biology/13_2.png,clip,13_2.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_8.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_8.png,groundtruth,26_8.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/6_2.png,MAC_Bench/Nature/Cover/Nature Cell Biology/6_2.png,vith,6_2.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/11_6.png,MAC_Bench/Nature/Cover/Nature Cell Biology/11_6.png,vitg,11_6.txt,test
Trends in Parasitology,40_8,Which of the following options best describe the cover story?,"Obesity or overweight is the result of consistent high-caloric diet
consumption. Obese adipose tissue is the niche of chronic low-grade inflammation that
spreads to other tissues and is mediated by pro-inflammatory innate cells, predominantly
M1 macrophages, neutrophils, T helper 1 cells, and their secretory cytokines. Helminths
such as hookworms induce an altered type-2 and anti-inflammatory immunomodulation
mediated primarily by M2 macrophages, eosinophils, basophils/mast cells, and
regulatory T cells. In this issue of Trends in Parasitology, Sikder et al. review the role of
helminths in reducing metabolic syndrome and discuss these protective mechanisms
for developing novel anti-diabetes drugs. The cover image shows adipose tissue
through scanning electron microscopy. Image credit: Getty Image/Steve Gschmeissner.",A,MAC_Bench/Cell/Cover/Trends in Parasitology/40_8.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_8.png,groundtruth,40_8.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/34_8.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_8.png,vith,34_8.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/27_11.png,MAC_Bench/Cell/Cover/Trends in Parasitology/27_11.png,vitg,27_11.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/26_5.png,MAC_Bench/Cell/Cover/Trends in Parasitology/26_5.png,clip,26_5.txt,train
Cell Systems,15_9,Which of the following options best describe the cover story?,"On the cover: 2nd and 3rd elementary landscapes (ELs) (top and middle, respectively)
and a linear combination of 2nd and 3rd ELs (bottom). Each vertex represents a unique
genotype, and colors indicate simulated fitness. Edges connect genotypes accessible
by a single mutation. In this issue of Cell Systems, Meger et al. experimentally characterize the DNA specificity landscape in the LacI/GalR family
of gene regulators, revealing its extreme ruggedness and providing insights into the
evolutionary dynamics shaping DNA specificity and regulatory function. Image credit:
the authors.",A,MAC_Bench/Cell/Cover/Cell Systems/15_9.png,MAC_Bench/Cell/Cover/Cell Systems/15_9.png,groundtruth,15_9.txt,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,vitg,7_2.txt,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,vith,11_2.txt,MAC_Bench/Cell/Cover/Cell Systems/8_1.png,MAC_Bench/Cell/Cover/Cell Systems/8_1.png,clip,8_1.txt,train
NATURE REVIEWS GENETICS,25_7,Which of the following options best describe the cover story?,"Inspired by the Review on p381
Cover design: Patrick Morgan",C,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_7.png,groundtruth,25_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/13_4.png,vitg,13_4.txt,train
CELL RESEARCH,35_1,Which of the following options best describe the cover story?,"The dual effects of glucocorticoids (GCs) are illustrated by bees. Left, low levels of GCs bind to the canonical high-affinity GC receptor (GR, the flower producing honey), mediating physiological and therapeutic effects. Right, high levels of GCs can also bind to the low-affinity receptor, tau, leading to bone loss and demonstrating pathological effects. See page 23–44 by Wenyu Fu et al. for details.",B,MAC_Bench/Nature/Cover/CELL RESEARCH/35_2.png,MAC_Bench/Nature/Cover/CELL RESEARCH/35_2.png,clip,35_2.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/35_1.png,MAC_Bench/Nature/Cover/CELL RESEARCH/35_1.png,groundtruth,35_1.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/31_4.png,MAC_Bench/Nature/Cover/CELL RESEARCH/31_4.png,ave_2,31_4.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,ave_3,34_10.txt,train
Science Signaling,2007_394,Which of the following options best describe the cover story?,"COVER This week's Focus Issue, published to complement the Science Special Issue on Undergraduate Education, contains an Editorial Guide as well as three Teaching Resources and the inaugural article for the new STKE Journal Club. [Classroom Image: Jupiter Images]",A,MAC_Bench/Science/Cover/Science Signaling/2007_394.png,MAC_Bench/Science/Cover/Science Signaling/2007_394.png,groundtruth,2007_394.txt,MAC_Bench/Science/Cover/Science Signaling/16_772.png,MAC_Bench/Science/Cover/Science Signaling/16_772.png,clip,16_772.txt,MAC_Bench/Science/Cover/Science Signaling/3_143.png,MAC_Bench/Science/Cover/Science Signaling/3_143.png,vith,3_143.txt,MAC_Bench/Science/Cover/Science Signaling/4_155.png,MAC_Bench/Science/Cover/Science Signaling/4_155.png,vitg,4_155.txt,train
Chem & Bio Engineering,2025_1,Which of the following options best describe the cover story?,Machine learning methods are used in industrial organic waste gasification to realize the accurate,C,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_1.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_1.png,clip,2024_1.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2025_1.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,vitg,2024_7.txt,train
Trendsin Neurosciences,47_2,Which of the following options best describe the cover story?,"Axonal regeneration is a highly complex process that requires the
coordinated action of multiple intracellular mechanisms. Unlike peripheral neurons,
central nervous system (CNS) neurons fail to activate a pro-regenerative program
following injury, resulting in severe neurological deficits. In this issue of Trends in
   Neurosciences, Diogo Tomé and Ramiro D. Almeida discuss the main intracellular
processes that drive the regenerative response and how their manipulation can
enhance the intrinsic growth capacity of injured CNS neurons. The cover features
an image of a growth cone (red), the precursor of axon regeneration, located at
the tip of a rat hippocampal axon (blue). The cover image was acquired by Diogo
Tomé and Ramiro D. Almeida.",C,MAC_Bench/Cell/Cover/Trendsin Neurosciences/36_2.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/36_2.png,vith,36_2.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_5.png,clip,38_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_2.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_2.png,groundtruth,47_2.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/46_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/46_5.png,vitg,46_5.txt,test
Cell Host&Microbe,32_9,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Host & Microbe, Zhou et al. explore the complex interactions between human microbiomes and their hosts across
different body sites, revealing that microbiome stability and its impact on health
are influenced by site-specific host factors. Their findings underscore the systemic
nature of host-microbiome relationships, with significant implications for understanding
metabolic diseases. Cover design by artist Lettie McGuire.",D,MAC_Bench/Cell/Cover/Cell Host&Microbe/17_2.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/17_2.png,clip,17_2.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,vitg,30_3.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,vith,31_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_9.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_9.png,groundtruth,32_9.txt,train
Nature Sustainability,7_2,Which of the following options best describe the cover story?,"Litigation and environment
Seeking environmental justice requires vast amounts of written law and armies of lawyers to adjudicate them fairly. Litigation between various types of stakeholders is a primary means of navigating these laws and should be studied for what it reveals about how environmental law impacts both nature and society.
See Editorial
Image and cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Sustainability/3_5.png,MAC_Bench/Nature/Cover/Nature Sustainability/3_5.png,ave_2,3_5.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_2.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_2.png,groundtruth,7_2.txt,MAC_Bench/Nature/Cover/Nature Sustainability/5_3.png,MAC_Bench/Nature/Cover/Nature Sustainability/5_3.png,clip,5_3.txt,MAC_Bench/Nature/Cover/Nature Sustainability/6_11.png,MAC_Bench/Nature/Cover/Nature Sustainability/6_11.png,vitg,6_11.txt,train
BDJ,237_3,Which of the following options best describe the cover story?,"In this issue
This issue features articles on peri-implantitis, implant-supported overdentures, and AI in oral medicine.

Cover image: From 2021. Our 2021 cover series recognising the strains placed on dental professionals in the wake of the coronavirus pandemic aimed to focus attention not only on the crossinfection control measures but also on the consequent human pressures. The cover on this issue (incorporating Vol 230 Issue 5, 12 March 2021) adds visual clues to some of the challenges we experienced in publishing during the pandemic.
©Tim Marrs, incorporating original photography by Filip Gierlinski",C,MAC_Bench/Nature/Cover/BDJ/233_2.png,MAC_Bench/Nature/Cover/BDJ/233_2.png,clip,233_2.txt,MAC_Bench/Nature/Cover/BDJ/234_2.png,MAC_Bench/Nature/Cover/BDJ/234_2.png,vitg,234_2.txt,MAC_Bench/Nature/Cover/BDJ/237_3.png,MAC_Bench/Nature/Cover/BDJ/237_3.png,groundtruth,237_3.txt,MAC_Bench/Nature/Cover/BDJ/237_6.png,MAC_Bench/Nature/Cover/BDJ/237_6.png,vith,237_6.txt,train
Nature Computational Science,4_5,Which of the following options best describe the cover story?,"Computational design of metamaterials
Metamaterials have garnered substantial research interest due to their ability to engineer materials properties not found in nature — which typically arise from specially designed structures — thus presenting unique opportunities across various fields. In order to facilitate the rational design of these metamaterials’ structures, computational methods have been widely employed, but numerous challenges remain to be addressed. This issue includes a Focus that consolidates the state-of-the-art computational algorithms for metamaterials design, highlighting current advancements, existing challenges, and future opportunities. In addition, the Focus explores challenges in manufacturing design and the potential applications of advanced metamaterials, such as optical and mechanical computing.
See Focus and Editorial
Image: OsakaWayne Studios / Moment / Getty Images. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Computational Science/2_3.png,MAC_Bench/Nature/Cover/Nature Computational Science/2_3.png,vith,2_3.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_5.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_5.png,groundtruth,4_5.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,clip,4_8.txt,MAC_Bench/Nature/Cover/Nature Computational Science/1_3.png,MAC_Bench/Nature/Cover/Nature Computational Science/1_3.png,vitg,1_3.txt,train
ACS Central Science,2024_2,Which of the following options best describe the cover story?,"The C–H silylation of methyl groups in complex terpenoids unlocks diverse transformations, including elimination, substitution with other functional groups, and integration into an expanded ring.",B,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_8.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_8.png,vitg,2024_8.txt,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_6.png,vith,2023_6.txt,test
Industrial & Engineering Chemistry Research,2024_20,Which of the following options best describe the cover story?,A new copolymer architecture is reported for mixed matrix membranes for CO2 capture. The corresponding grafted multi-block copolymer strongly improved filler/polymer compatibility up to high loadings of ZIF-8 (40 vol %) and the membrane CO2 permeability was increased by a factor 6 compared to the corresponding unloaded membrane.,D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_6.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2018_19.png,clip,2018_19.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,vitg,2024_36.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_20.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_20.png,groundtruth,2024_20.txt,val
Molecular Pharmaceutics,2024_9,Which of the following options best describe the cover story?,"Liquid droplets (top left) generated from antibodies (red) and polyglutamate (green) were formulated into lipid nanoparticles (purple). Through this magic, the antibodies were effectively delivered into cells to bind target proteins in the cytosol (green).",A,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_9.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,ave_2,2020_4.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,clip,2022_8.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_2.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_2.png,vith,2020_2.txt,train
Crystal Growth & Design,2024_2,Which of the following options best describe the cover story?,"For the first time a N,N-chelating ligand, bis(4-iodopyrazol-1-yl)methane is explored as a halogen bond donor in piano-stool half-sandwich noble metal complexes.",A,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,ave_2,2019_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_11.png,vitg,2019_11.txt,train
Current Biology,34_7,Which of the following options best describe the cover story?,"On the cover: Confocal micrograph of an adult Drosophila melanogaster flight muscle under pressure: myofibrils (magenta) and mitochondria (cyan) build
up pressure on nuclei, in which Tono (yellow) responds by forming round droplets.
Here, pressure was increased externally by incubation in a hyper-osmotic solution
(200 mM NaCl) prior to fixation; as a consequence, Tono formed large droplets. In
this issue, Zhang, Avellaneda, et al. demonstrate that the BTB-Zn finger protein Tono is required for myogenesis. Without
Tono, myofibrils and mitochondria remain immature, muscles do not work, and flies
can neither fly nor jump. Tono is present in the muscle nuclei and responds to internal
and external mechanical pressure on the nuclei by forming small or large droplets.
The authors propose that Tono measures the internal pressure status to adapt the transcriptional
program of the developing flight muscles, which in turn supports myofibril and mitochondria
maturation. Similar mechanosensitive BTB-Zn finger proteins may exist in humans. Image
acquired by Jerome Avellaneda.",A,MAC_Bench/Cell/Cover/Current Biology/34_7.png,MAC_Bench/Cell/Cover/Current Biology/34_7.png,groundtruth,34_7.txt,MAC_Bench/Cell/Cover/Current Biology/34_23.png,MAC_Bench/Cell/Cover/Current Biology/34_23.png,clip,34_23.txt,MAC_Bench/Cell/Cover/Current Biology/27_6.png,MAC_Bench/Cell/Cover/Current Biology/27_6.png,vitg,27_6.txt,MAC_Bench/Cell/Cover/Current Biology/20_12.png,MAC_Bench/Cell/Cover/Current Biology/20_12.png,vith,20_12.txt,train
Journal of Chemical Theory and Computation,2024_10,Which of the following options best describe the cover story?,The new open source QupKake model from Abarbanel and Hutchison combines fast semiempirical quantum chemical data with machine learning methods to predict the local aqueous pKa of atomic sites in organic molecules for both protonation and deprotonation.,A,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_10.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_18.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_18.png,ave_2,2023_18.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_22.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_22.png,vitg,2023_22.txt,train
ACS Chemical Neuroscience,2024_13,Which of the following options best describe the cover story?,The crosstalks between multiple post-translational modifications in the first 17 residues of huntingtin protein differentially modulate its conformation and interaction with various lipid membranes.,C,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2025_4.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2025_4.png,vith,2025_4.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_13.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_13.png,vitg,2021_13.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_13.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_13.png,groundtruth,2024_13.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_18.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_18.png,clip,2020_18.txt,train
NATURE ENERGY,9_5,Which of the following options best describe the cover story?,"Disrupting gender norms
A just and equitable energy transition requires addressing historically embedded gender norms. Michael and Ahlborg shed light on the Solar Mamas programme in Zanzibar as an example for how locally led, contextually grounded energy interventions prioritizing care work and women’s knowledge may contribute to disrupting established norms.
See Michael and Ahlborg and Research Briefing
Image: Olga Timokhina, La Fabrika Films. Cover design: Thomas Phillips.",B,MAC_Bench/Nature/Cover/NATURE ENERGY/1_2.png,MAC_Bench/Nature/Cover/NATURE ENERGY/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_5.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_5.png,groundtruth,9_5.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/4_1.png,MAC_Bench/Nature/Cover/NATURE ENERGY/4_1.png,vitg,4_1.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/6_8.png,MAC_Bench/Nature/Cover/NATURE ENERGY/6_8.png,vith,6_8.txt,train
Structure,32_9,Which of the following options best describe the cover story?,"On the cover: The cover figure, from Bartoš et al., shows the insertase protein MTCH2 scrambling lipids in the membrane. While the primary
function of insertases is the insertion of proteins into membranes, MTCH2 stands out
by also scrambling lipids thanks to its hydrophilic pathway that locally disrupts
the membrane. Thus, certain insertases and scramblases may share a common mechanism
of function. Image courtesy of Lukáš Sukeník.",C,MAC_Bench/Cell/Cover/Structure/20_1.png,MAC_Bench/Cell/Cover/Structure/20_1.png,clip,20_1.txt,MAC_Bench/Cell/Cover/Structure/33_2.png,MAC_Bench/Cell/Cover/Structure/33_2.png,vitg,33_2.txt,MAC_Bench/Cell/Cover/Structure/32_9.png,MAC_Bench/Cell/Cover/Structure/32_9.png,groundtruth,32_9.txt,MAC_Bench/Cell/Cover/Structure/24_12.png,MAC_Bench/Cell/Cover/Structure/24_12.png,vith,24_12.txt,train
Cell Host&Microbe,32_2,Which of the following options best describe the cover story?,"On the cover: The cover is a Chinese ink wash painting depicting bees collecting pollens
from plum blossoms, which symbolize wisdom in Chinese traditional culture. In this
issue of Cell Host & Microbe, Zhong et al. reveal that honeybee gut microbiota influence reward learning by mediating the metabolism
of pollen fatty acids. Bacteria facilitates the conversion of linoleic acid to anandamide,
which activates TRPA receptors in astrocytes. This triggers the endocannabinoid system
and regulates glutamate/GABA balance in bee brain, ultimately enhancing honeybee reward
learning and memory.",A,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_2.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_2.png,groundtruth,32_2.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/15_1.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/15_1.png,vitg,15_1.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_4.png,clip,27_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_2.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_2.png,vith,31_2.txt,val
CELL RESEARCH,34_4,Which of the following options best describe the cover story?,"The image depicts the Chinese legend ""The Magic Brush"" (""Shen Bi Ma Liang""). The towering mountain symbolizes the rugged protein fitness landscape, with reaching the summit representing the challenging tasks in protein engineering. Our proposed method, ProMEP, serves as the magic brush, sketching out a rapid path to the peak for biologists. The brush’s handle, adorned with dots, lines, and jewels, signifies the power of artificial intelligence technology driving this journey. See page 630–647 by Peng Cheng et al. for details.",C,MAC_Bench/Nature/Cover/CELL RESEARCH/29_3.png,MAC_Bench/Nature/Cover/CELL RESEARCH/29_3.png,vith,29_3.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_1.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_1.png,clip,32_1.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_4.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_4.png,groundtruth,34_4.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_8.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_8.png,vitg,34_8.txt,train
Science Immunology,9_95,Which of the following options best describe the cover story?,"ONLINE COVER NK Cells Enforce a T Cell Checkpoint. Natural killer (NK) cells can eliminate infected or malignant cells, but how and when NK cell cytolytic activity is directed against host immune cells is not fully understood. Kilian et al. found that the expression of the NKp30 ligand B7H6 by activated human T cells promoted their cytolysis by NKp30+ NK cells. NK cells restricted the antitumor activity of B7H6+ chimeric antigen receptor (CAR) T cells and were associated with poor immunotherapy responses in patients with esophageal cancer. This month’s cover depicts an NK cell (light blue) decorated with NKp30 (blue surface receptor) killing an antitumoral T cell (yellow) that expresses B7H6 (orange surface ligand). Other T cells lacking B7H6 are spared and can continue targeting cancer cells with their own cytotoxic granules. Credit: N. Burgess/Science Immunology",A,MAC_Bench/Science/Cover/Science Immunology/9_95.png,MAC_Bench/Science/Cover/Science Immunology/9_95.png,groundtruth,9_95.txt,MAC_Bench/Science/Cover/Science Immunology/2_11.png,MAC_Bench/Science/Cover/Science Immunology/2_11.png,ave_0,2_11.txt,MAC_Bench/Science/Cover/Science Immunology/2_10.png,MAC_Bench/Science/Cover/Science Immunology/2_10.png,vitg,2_10.txt,MAC_Bench/Science/Cover/Science Immunology/3_28.png,MAC_Bench/Science/Cover/Science Immunology/3_28.png,clip,3_28.txt,train
Science Signaling,2007_391,Which of the following options best describe the cover story?,"COVER This week features a Perspective on ubiquitination of the estrogen receptor by the BRCA1 complex. The image depicts a model of BRCA1 involvement in estrogen receptor ubiquitination. [Image: Christopher Bickel, AAAS]",C,MAC_Bench/Science/Cover/Science Signaling/5_250.png,MAC_Bench/Science/Cover/Science Signaling/5_250.png,vitg,5_250.txt,MAC_Bench/Science/Cover/Science Signaling/1_48.png,MAC_Bench/Science/Cover/Science Signaling/1_48.png,clip,1_48.txt,MAC_Bench/Science/Cover/Science Signaling/2007_391.png,MAC_Bench/Science/Cover/Science Signaling/2007_391.png,groundtruth,2007_391.txt,MAC_Bench/Science/Cover/Science Signaling/5_245.png,MAC_Bench/Science/Cover/Science Signaling/5_245.png,vith,5_245.txt,val
Nature Chemical Engineering,1_4,Which of the following options best describe the cover story?,"Stirring up plastics recycling
Emerging catalytic techniques can valorize plastic waste into valuable products. In addition to the ongoing search for more effective catalysts, disclosing the potential of these technologies requires dedicated reaction engineering efforts. Now, Javier Pérez-Ramírez and co-workers show how critical optimal mixing is in the three-phase hydrogenolysis of polyolefins. Following catalytic evaluation and computational fluid dynamics simulations, they derive an accessible quantitative criterion for determining stirring configurations to maximize catalyst effectiveness. This marks an important step towards standardized benchmarking of catalytic technologies. The cover depicts the top view of catalyst particle trajectories in a plastic melt when stirred with the optimal geometry.
See Jaydev et al. and Soltani & Rorrer
Image: Constance Ko and Javier Pérez-Ramírez, ETH Zurich. Cover design: Thomas Phillips.",C,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,vitg,1_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_4.png,groundtruth,1_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_9.png,ave_1,1_9.txt,test
Acta Pharmacologica Sinica,45_12,Which of the following options best describe the cover story?,"Cover Credit: DZ2002, a reversible inhibitor of type III S-adenosyl-L-homocysteine hydrolase, attenuates TNF-α-induced NF-κB signaling by suppressing the degradation and phosphorylation of IκB, along with NF-κB p65 phosphorylation and nuclear translocation. Additionally, DZ2002 inhibits the activation of molecules in the STAT3-PI3K-Akt pathway, suppressing the secretion of inflammatory cytokines and pro-angiogenic factors. These findings strongly support DZ2002's promising therapeutic potential for dry eye disease (DED).",A,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_12.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_12.png,groundtruth,45_12.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_5.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_5.png,clip,42_5.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_12.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_12.png,vith,42_12.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_2.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/42_2.png,vitg,42_2.txt,train
ACS Applied Energy Materials,2025_3,Which of the following options best describe the cover story?,"The cover art illustrates a porous carbon electrode integrated with a conductive, interconnected substrate. The heat dissipation within the porous structure represents efficient thermal management and electron transport, essential for high-performance energy-storage systems. The structured carbon layer facilitates ion diffusion and charge storage, emphasizing advancements in electrode design for battery technologies.",B,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2025_3.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2023_13.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2023_13.png,vitg,2023_13.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2019_8.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2019_8.png,ave_1,2019_8.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_3,Which of the following options best describe the cover story?,"A golden age for muscarinic receptors as targets for neurological diseases, inspired by the Review on p743.
Cover design: S. Harris",C,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_2.png,ave_1,20_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_4.png,vitg,19_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_3.png,groundtruth,23_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_1.png,clip,22_1.txt,val
Biophysical Journal,124_4,Which of the following options best describe the cover story?,"Cover picture: This image shows a snapshot of our computational model of the nuclear pore complex
(NPC). The NPC is a large protein complex embedded in the nuclear membrane, and it
is responsible for all transport into and out of the nucleus. This is mediated by
numerous intrinsically disordered proteins (IDPs; the filaments in the image). To
control transport, the NPC is highly selective: only very specific proteins and nucleic
acids are allowed to pass through by binding to specialized transporter proteins.
To shed light on this process, we developed a coarse-grained molecular dynamics model
that allowed us to study the transport of these proteins (blue spheres in the image) through the IDP meshwork. The image shows a cut-open view of the NPC
with IDPs (the different bead colors correspond to different amino acids) anchored
to the inner walls of the scaffold, with blue transport proteins transporting through
the NPC. DOI: 10.1016/j.bpj.2024.11.3313.",A,MAC_Bench/Cell/Cover/Biophysical Journal/124_4.png,MAC_Bench/Cell/Cover/Biophysical Journal/124_4.png,groundtruth,124_4.txt,MAC_Bench/Cell/Cover/Biophysical Journal/109_5.png,MAC_Bench/Cell/Cover/Biophysical Journal/109_5.png,vitg,109_5.txt,MAC_Bench/Cell/Cover/Biophysical Journal/123_9.png,MAC_Bench/Cell/Cover/Biophysical Journal/123_9.png,clip,123_9.txt,MAC_Bench/Cell/Cover/Biophysical Journal/123_3.png,MAC_Bench/Cell/Cover/Biophysical Journal/123_3.png,vith,123_3.txt,train
Science Signaling,2007_410,Which of the following options best describe the cover story?,"COVER This week's Focus Issue, published in conjunction with the Science Special Collection on Decision-Making, highlights cellular decision-making events (see the Editorial Guide). The image depicts a neuronal stem cell and its potential fates of a glia or a neuron. [Image: Christopher Bickel, AAAS]",D,MAC_Bench/Science/Cover/Science Signaling/8_382.png,MAC_Bench/Science/Cover/Science Signaling/8_382.png,vith,8_382.txt,MAC_Bench/Science/Cover/Science Signaling/2_79.png,MAC_Bench/Science/Cover/Science Signaling/2_79.png,vitg,2_79.txt,MAC_Bench/Science/Cover/Science Signaling/7_336.png,MAC_Bench/Science/Cover/Science Signaling/7_336.png,clip,7_336.txt,MAC_Bench/Science/Cover/Science Signaling/2007_410.png,MAC_Bench/Science/Cover/Science Signaling/2007_410.png,groundtruth,2007_410.txt,train
Industrial & Engineering Chemistry Research,2024_9,Which of the following options best describe the cover story?,"Chemical-looping-based oxidative dehydrogenation of ethane to ethylene with successive CO2 activation to CO was verified on FeMTiOx mixed metal oxides (M = Ni, Sn, Co, Mn, Ce).",A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_9.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_23.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_23.png,ave_1,2022_23.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,clip,2024_36.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,val
Nature Neuroscience,28_1,Which of the following options best describe the cover story?,"Constraints on neural dynamics
The time course of neural activity is thought to be essential for computation in networks of neurons. Oby, Degenhart, Grigsby and colleagues used a brain–computer interface to show that activity time courses in the brain are difficult to violate, which provides empirical support for dynamical principles at play. The cover illustrates a monkey traversing a time course of neural activity unfolding in its brain.
See Oby, Degenhart, Grigsby, et al.
Image design: Avesta Rastan. Cover design: Marina Spence",A,MAC_Bench/Nature/Cover/Nature Neuroscience/28_1.png,MAC_Bench/Nature/Cover/Nature Neuroscience/28_1.png,groundtruth,28_1.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/8_4.png,MAC_Bench/Nature/Cover/Nature Neuroscience/8_4.png,vith,8_4.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/18_12.png,MAC_Bench/Nature/Cover/Nature Neuroscience/18_12.png,clip,18_12.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/14_6.png,MAC_Bench/Nature/Cover/Nature Neuroscience/14_6.png,ave_1,14_6.txt,train
Molecular Cell,85_2,Which of the following options best describe the cover story?,"On the cover: This special issue explores emerging ideas about patterns in molecular
biology, highlighting connections across different molecular processes and their collective
contribution to the function of the cell. The cover shows the patterned organization
of DNA and chromatin into higher-order structures superimposed on the fractal architecture
of the fiddlehead fern, with chromosome territories enlarging from spores originating
in the fern’s leaves. Cover artwork by Sonhita Chakraborty (artbysonhita.com).",D,MAC_Bench/Cell/Cover/Molecular Cell/46_4.png,MAC_Bench/Cell/Cover/Molecular Cell/46_4.png,vith,46_4.txt,MAC_Bench/Cell/Cover/Molecular Cell/82_11.png,MAC_Bench/Cell/Cover/Molecular Cell/82_11.png,vitg,82_11.txt,MAC_Bench/Cell/Cover/Molecular Cell/37_1.png,MAC_Bench/Cell/Cover/Molecular Cell/37_1.png,clip,37_1.txt,MAC_Bench/Cell/Cover/Molecular Cell/85_2.png,MAC_Bench/Cell/Cover/Molecular Cell/85_2.png,groundtruth,85_2.txt,train
Cell Reports,43_12,Which of the following options best describe the cover story?,"On the cover: Spring represents a critical period of growth analogous to the critical
period for ocular dominance (OD) plasticity. The image depicts mice using vision to
hunt crickets under a fused tree crown representing the superior colliculus (SC).
In this issue, Hu and Chen et al. find that the critical period for OD plasticity in the mouse SC is independent of
the primary visual cortex and requires NMDA receptors. Concept and artwork: Xuefeng
Shi and Yanbing Shi.",C,MAC_Bench/Cell/Cover/Cell Reports/13_11.png,MAC_Bench/Cell/Cover/Cell Reports/13_11.png,ave_0,13_11.txt,MAC_Bench/Cell/Cover/Cell Reports/11_5.png,MAC_Bench/Cell/Cover/Cell Reports/11_5.png,clip,11_5.txt,MAC_Bench/Cell/Cover/Cell Reports/43_12.png,MAC_Bench/Cell/Cover/Cell Reports/43_12.png,groundtruth,43_12.txt,MAC_Bench/Cell/Cover/Cell Reports/9_4.png,MAC_Bench/Cell/Cover/Cell Reports/9_4.png,vitg,9_4.txt,train
Nature Geoscience,17_6,Which of the following options best describe the cover story?,"Water frost on Martian mountaintops
High-resolution spacecraft imagery has revealed transient deposits that appear in the early mornings of cold seasons at high altitudes on Mars, consistent with water frost of atmospheric origin. The image shows bluish water frost deposited on the caldera of Olympus Mons — the tallest known volcano in the Solar System — on a cold winter morning. The observations highlight the dynamic microclimate of the Tharsis volcanic province and its role in the broader Martian water cycle.
See Valantinas et al.
Image: ESA/DLR/FU Berlin/A. Valantinas. Cover design: Alex Whitworth",D,MAC_Bench/Nature/Cover/Nature Geoscience/14_11.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_11.png,clip,14_11.txt,MAC_Bench/Nature/Cover/Nature Geoscience/13_10.png,MAC_Bench/Nature/Cover/Nature Geoscience/13_10.png,vith,13_10.txt,MAC_Bench/Nature/Cover/Nature Geoscience/3_4.png,MAC_Bench/Nature/Cover/Nature Geoscience/3_4.png,vitg,3_4.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_6.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_6.png,groundtruth,17_6.txt,val
Matter,7_3,Which of the following options best describe the cover story?,"On the cover: Morphology of the one-dimensional titania-based material when its aqueous
colloidal suspension is mixed with a water-miscible organic solvent. The one-dimensional
nature of the material is manifest here, as described in the work of Li and colleagues. Such tunable liquid crystalline phases could open new opportunities to realize 1DL
in multiple applications. Scanning electron microscope micrograph taken by G. Schwenk
and artistically rendered by Patricia Lyons of Moorestown NJ.",A,MAC_Bench/Cell/Cover/Matter/7_3.png,MAC_Bench/Cell/Cover/Matter/7_3.png,groundtruth,7_3.txt,MAC_Bench/Cell/Cover/Matter/2_6.png,MAC_Bench/Cell/Cover/Matter/2_6.png,vitg,2_6.txt,MAC_Bench/Cell/Cover/Matter/1_6.png,MAC_Bench/Cell/Cover/Matter/1_6.png,vith,1_6.txt,MAC_Bench/Cell/Cover/Matter/4_12.png,MAC_Bench/Cell/Cover/Matter/4_12.png,clip,4_12.txt,train
BDJ,237_8,Which of the following options best describe the cover story?,"In this issue
This Orthodontic-Restorative Interface themed issue features articles on orthodontics and perio, orthodontics and implants, and orthodontics and tooth wear.

Cover image: From 2012. The retrospective cover which forms the centrepiece of the cover image of this issue is from the 2012 London Olympics series (Volume 212 Issue 4, 25 February 2012). Despite years of gloom by naysayers that the London venue would spell doom, gloom and chaos, the reality turned out to be a happy and joyous celebration completely within the Olympic spirit. Centred on this occasion is a relay race with the passing of the baton but substituting a toothbrush.
©Tim Marrs, incorporating original cover art by Russ Tudor",A,MAC_Bench/Nature/Cover/BDJ/237_8.png,MAC_Bench/Nature/Cover/BDJ/237_8.png,groundtruth,237_8.txt,MAC_Bench/Nature/Cover/BDJ/228_9.png,MAC_Bench/Nature/Cover/BDJ/228_9.png,clip,228_9.txt,MAC_Bench/Nature/Cover/BDJ/234_4.png,MAC_Bench/Nature/Cover/BDJ/234_4.png,vith,234_4.txt,MAC_Bench/Nature/Cover/BDJ/238_2.png,MAC_Bench/Nature/Cover/BDJ/238_2.png,vitg,238_2.txt,train
Accounts of Chemical Research,2024_2,Which of the following options best describe the cover story?,"2D semiconducting molybdenum disulfide (MoS2) has attracted huge interest in extending Moore’s law beyond silicon. This account briefly reviews recent research advances and presents the authors’ own insights into the mechanisms of controllable growth, defect repairing and Ohmic contact of MoS2 as well as the standing challenges.",D,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_9.png,ave_0,2020_9.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_17.png,clip,2022_17.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_4.png,vitg,2014_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_2.png,groundtruth,2024_2.txt,test
Structure,32_8,Which of the following options best describe the cover story?,"On the cover: The cover image from our Voices author Helen Ginn shows a representation of the symbiosis between computing and structural biology.
Visualization of the nanoscale natural world was made possible only after the advent
of computers. The use of computers allows us to build, visualize, and interrogate
conceptual models of the otherwise unobservable. Structural biology shows us the questions
we need to learn how to answer. Structural biology is forever intertwined with the
computational development of algorithms to help answer these fundamental question.",C,MAC_Bench/Cell/Cover/Structure/19_12.png,MAC_Bench/Cell/Cover/Structure/19_12.png,clip,19_12.txt,MAC_Bench/Cell/Cover/Structure/28_12.png,MAC_Bench/Cell/Cover/Structure/28_12.png,vitg,28_12.txt,MAC_Bench/Cell/Cover/Structure/32_8.png,MAC_Bench/Cell/Cover/Structure/32_8.png,groundtruth,32_8.txt,MAC_Bench/Cell/Cover/Structure/26_12.png,MAC_Bench/Cell/Cover/Structure/26_12.png,vith,26_12.txt,test
Developmental Cell,60_3,Which of the following options best describe the cover story?,"On the cover: Sex differences originate early in human postnatal T cell development.
The image represents the different developmental paths male (green) and female (purple)
T cells take during differentiation and training in the thymus. Sex differences in
thymic niches and T cell developmental trajectories are depicted by analogous but
distinct white nodes, representing sex biases in thymic niches, which we identified
using our spatial multi-omics thymus resource. To learn more about how the authors
use spatial multi-omics to identify sex differences in T cell development and thymus
biology, see Stankiewicz et al. Image credit: Jen Ma.",B,MAC_Bench/Cell/Cover/Developmental Cell/29_2.png,MAC_Bench/Cell/Cover/Developmental Cell/29_2.png,clip,29_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/60_3.png,MAC_Bench/Cell/Cover/Developmental Cell/60_3.png,groundtruth,60_3.txt,MAC_Bench/Cell/Cover/Developmental Cell/43_5.png,MAC_Bench/Cell/Cover/Developmental Cell/43_5.png,ave_0,43_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/37_1.png,MAC_Bench/Cell/Cover/Developmental Cell/37_1.png,vith,37_1.txt,train
BDJ,237_2,Which of the following options best describe the cover story?,"In this issue
This issue features articles on mental health, oral cancer inequalities, and autism spectrum condition

Cover image: From 2023. For this issue, we celebrate the cover series from last year which aimed to consider the UNs’ Sustainable Development Goals (SDGs) and the relevance they have to dentistry, our patients and their oral health. Although there are 17 SDGs, we only have 12 covers in a volume so we had to select the dozen that we felt were most appropriate for this purpose but not necessarily the most important overall – as depicted in the future-gazing professional on this cover’s revisit (Volume 235 Issue 1, 14 July 2023).
©Tim Marrs, incorporating original artwork by Kate Miller",B,MAC_Bench/Nature/Cover/BDJ/235_1.png,MAC_Bench/Nature/Cover/BDJ/235_1.png,vitg,235_1.txt,MAC_Bench/Nature/Cover/BDJ/237_2.png,MAC_Bench/Nature/Cover/BDJ/237_2.png,groundtruth,237_2.txt,MAC_Bench/Nature/Cover/BDJ/235_4.png,MAC_Bench/Nature/Cover/BDJ/235_4.png,vith,235_4.txt,MAC_Bench/Nature/Cover/BDJ/229_6.png,MAC_Bench/Nature/Cover/BDJ/229_6.png,clip,229_6.txt,test
NATURE IMMUNOLOGY,25_3,Which of the following options best describe the cover story?,"Targeting immune evasion in ovarian cancer
Jerby and colleagues present a spatial transcriptomics analysis of ovarian cancer. The image depicts the tumor microenvironment; T cells are in red, tumor cells are in gray, and each dot depicts a single RNA molecule.
See Yeh et al.
Image: Christine Yeh, Stanford University. Cover design: Emily Paul",A,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_3.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_3.png,groundtruth,25_3.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/7_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/7_12.png,vith,7_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/15_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/15_5.png,clip,15_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_10.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_10.png,vitg,10_10.txt,train
Molecular Therapy,32_16,Which of the following options best describe the cover story?,"On the cover: The image displays GALC enzyme (red) in Purkinje cells of a dog affected with Krabbe
disease after receiving combination HSCT and systemic AAV-cGALC gene therapy as detailed
in Bradbury et al. Image credit: Allison Bradbury and Gary Swain.",B,MAC_Bench/Cell/Cover/Molecular Therapy/32_1.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_1.png,vitg,32_1.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_16.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_16.png,groundtruth,32_16.txt,MAC_Bench/Cell/Cover/Molecular Therapy/25_12.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_12.png,vith,25_12.txt,MAC_Bench/Cell/Cover/Molecular Therapy/28_7.png,MAC_Bench/Cell/Cover/Molecular Therapy/28_7.png,clip,28_7.txt,val
ACS Physical Chemistry Au,2024_4,Which of the following options best describe the cover story?,Resonance Raman signals from the amide and disulfide linkages provide invaluable insights into the secondary structural changes during the phase separation of soluble bovine insulin monomers to insoluble amyloid fibers. Illustration by Uttam Pal.,A,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2021_1.png,clip,2021_1.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_2.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2022_2.png,vitg,2022_2.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_3.png,vith,2024_3.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_9,Which of the following options best describe the cover story?,"‘Cell–cell junctions and tissue mechanics’, inspired by the Review on p252
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_4.png,vith,23_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_9.png,groundtruth,25_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/19_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/19_6.png,vitg,19_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_8.png,clip,15_8.txt,train
ACS Applied Polymer Materials,2024_13,Which of the following options best describe the cover story?,"Here a dual-network hydrogel flexible sensor produced from polyvinyl alcohol and gelatin offers exceptional ductility, self-adhesion, anti-bacteria, and high sensitivity for strain detection. The potential of this flexible sensor to detect body movements with transmitting underwater Morse code signals indicates a significant advancement for various monitoring applications.",A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_13.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_13.png,groundtruth,2024_13.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_21.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_21.png,vith,2024_21.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_9.png,clip,2023_9.txt,train
NATURE REVIEWS MICROBIOLOGY,22_11,Which of the following options best describe the cover story?,"Soil plastic pollution, inspired by the Review on p64.
Cover design: Philip Patenall.",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/15_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/15_3.png,clip,15_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_8.png,vitg,21_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_6.png,vith,20_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_11.png,groundtruth,22_11.txt,train
Immunity,57_11,Which of the following options best describe the cover story?,"On the cover: Disease-associated microglia (DAMs) are associated with various neurological
disorders. In this issue, Lan et al. examine the plasticity and fate of DAMs during brain injury and recovery in juvenile
and neonatal mice and find that in the neonatal stroke models, DAM-like microglia
regained a homeostatic signature and integrated into the microglial network after
recovery but remained sensitized to subsequent immune challenges. Some microglia remain
within the core injury region, perishing alongside the damaged cells. However, other
microglia escape the infarct core, migrating away from the injury region and regaining
homeostatic features, akin to soaring butterflies rising from the ashes. Image created
by Zhong Wei and Yangning Lan.",C,MAC_Bench/Cell/Cover/Immunity/58_2.png,MAC_Bench/Cell/Cover/Immunity/58_2.png,clip,58_2.txt,MAC_Bench/Cell/Cover/Immunity/42_4.png,MAC_Bench/Cell/Cover/Immunity/42_4.png,vith,42_4.txt,MAC_Bench/Cell/Cover/Immunity/57_11.png,MAC_Bench/Cell/Cover/Immunity/57_11.png,groundtruth,57_11.txt,MAC_Bench/Cell/Cover/Immunity/36_6.png,MAC_Bench/Cell/Cover/Immunity/36_6.png,vitg,36_6.txt,train
Organometallics,2025_3,Which of the following options best describe the cover story?,"A display of ingenuity: A modular synthesis of rigid chelating naphthyridine-based bis(carbene) ligands, coined the ""NBC"" scaffold, has been unlocked. With the cashing in on this new ligand scaffold, the bulkiest version supports a rare collection of diverse structures of the coinage metal series, consisting of mononuclear trigonal planar species with Cu(I) and Ag(I) and a dinuclear complex with Au(I). The cover art was designed and created by lead author Evan Patrick.",B,MAC_Bench/ACS/Cover/Organometallics/2023_15.png,MAC_Bench/ACS/Cover/Organometallics/2023_15.png,vith,2023_15.txt,MAC_Bench/ACS/Cover/Organometallics/2025_3.png,MAC_Bench/ACS/Cover/Organometallics/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Organometallics/2024_22.png,MAC_Bench/ACS/Cover/Organometallics/2024_22.png,ave_3,2024_22.txt,MAC_Bench/ACS/Cover/Organometallics/2022_17.png,MAC_Bench/ACS/Cover/Organometallics/2022_17.png,clip,2022_17.txt,train
Biomacromolecules,2024_12,Which of the following options best describe the cover story?,"A chitosan-based hydrogel that enables sustained and controlled delivery of a temoporfin derivative, which permits multiple irradiations after a single intratumoral administration. This strategy combines efficient cell killing with antitumor immunity.",A,MAC_Bench/ACS/Cover/Biomacromolecules/2024_12.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2020_3.png,MAC_Bench/ACS/Cover/Biomacromolecules/2020_3.png,clip,2020_3.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2017_3.png,MAC_Bench/ACS/Cover/Biomacromolecules/2017_3.png,vitg,2017_3.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2023_11.png,MAC_Bench/ACS/Cover/Biomacromolecules/2023_11.png,vith,2023_11.txt,test
Nature Cell Biology,26_3,Which of the following options best describe the cover story?,"Heritable amyloids
Protein amyloid structures are stably inherited across generations and transmit epigenetic memory in Caenorhabditis elegans. Loss of MSTR, a regulator of the amyloid-like structures, results in a transgenerational feminization phenotype.
See Eroglu et al.
Image: Matthew Eroglu, SickKids Hospital & University of Toronto. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Cell Biology/7_2.png,MAC_Bench/Nature/Cover/Nature Cell Biology/7_2.png,clip,7_2.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_3.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_3.png,groundtruth,26_3.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/16_3.png,MAC_Bench/Nature/Cover/Nature Cell Biology/16_3.png,vitg,16_3.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/20_11.png,MAC_Bench/Nature/Cover/Nature Cell Biology/20_11.png,vith,20_11.txt,train
NATURE REVIEWS MICROBIOLOGY,22_10,Which of the following options best describe the cover story?,"Honeybee gut microbiota, inspired by the Review on p122.
Cover design: Philip Patenall.",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/18_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/18_6.png,ave_2,18_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_7.png,clip,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/14_4.png,ave_3,14_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_10.png,groundtruth,22_10.txt,train
Nature Reviews Endocrinology,20_8,Which of the following options best describe the cover story?,"Sarcopenic obesity in older adults, inspired by the Review on p261.
Cover design: Jennie Vallis",C,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/9_3.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/9_3.png,vitg,9_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,vith,18_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_8.png,groundtruth,20_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_2.png,clip,19_2.txt,train
Nature Reviews Electrical Engineering,1_11,Which of the following options best describe the cover story?,"Block copolymer (BCP) self-assembly provides sub-10-nm periodic nanopatterned structures to fabricate internet of things (IoT) hardware components with a cost-effective, large-area approach and versatile functionalities. The cover image illustrates the BCP architecture library and the potential components for IoT applications. See Kim et al.
Cover design: Sam Whitham",D,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,ave_2,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_8.png,ave_1,1_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_11.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_11.png,groundtruth,1_11.txt,train
Caner Cell,42_9,Which of the following options best describe the cover story?,"On the cover: In this issue of Cancer Cell, two papers by Barisic et al. and Deng et al. evaluate how mutations in components of the BAF complex lead to the development of
B cell malignancies. In the cover, Barisic et al. demonstrate that ARID1A is required
for continuous eviction of nucleosomes, facilitating the sequential binding of transcription
factors necessary for safeguarding germinal center B cell fate towards plasma cells.
The cover image symbolizes ARID1A as Sisyphus, exerting significant effort and energy
to push boulders uphill, analogous to the BAF complex and ARID1A using energy from
ATP hydrolysis for nucleosome eviction. Birds in the image symbolize the antibodies
produced by plasma cells when ARID1A effectively remodels nucleosomes. Credit: Art
by Inmywork Studio.",C,MAC_Bench/Cell/Cover/Caner Cell/32_2.png,MAC_Bench/Cell/Cover/Caner Cell/32_2.png,clip,32_2.txt,MAC_Bench/Cell/Cover/Caner Cell/23_2.png,MAC_Bench/Cell/Cover/Caner Cell/23_2.png,vith,23_2.txt,MAC_Bench/Cell/Cover/Caner Cell/42_9.png,MAC_Bench/Cell/Cover/Caner Cell/42_9.png,groundtruth,42_9.txt,MAC_Bench/Cell/Cover/Caner Cell/22_1.png,MAC_Bench/Cell/Cover/Caner Cell/22_1.png,vitg,22_1.txt,test
ACS Catalysis,2025_2,Which of the following options best describe the cover story?,The catalytic activity of LaCoO3 perovskite toward toluene oxidation can be improved by A-site defects regulation and the Rs is closely associated with the O p-band center.,B,MAC_Bench/ACS/Cover/ACS Catalysis/2020_4.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_4.png,vith,2020_4.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2025_2.png,MAC_Bench/ACS/Cover/ACS Catalysis/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2020_14.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_14.png,vitg,2020_14.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2019_9.png,MAC_Bench/ACS/Cover/ACS Catalysis/2019_9.png,clip,2019_9.txt,train
Joule,8_6,Which of the following options best describe the cover story?,"On the cover: In this issue, Yi et al. introduce a simple method to fabricate high-quality perovskite films at room temperature
by precisely regulating the perovskite composition with an organic linker. The cover
art depicts perovskite films on natural leaves, which can be fabricated using this
method without thermal annealing. The optimized device achieved an impressive efficiency
of 24.4%, surpassing the efficiencies of previous room/low-temperature-processed perovskite
solar cells. Image credit: Jeongung Cho (3D Morph).",A,MAC_Bench/Cell/Cover/Joule/8_6.png,MAC_Bench/Cell/Cover/Joule/8_6.png,groundtruth,8_6.txt,MAC_Bench/Cell/Cover/Joule/3_8.png,MAC_Bench/Cell/Cover/Joule/3_8.png,vith,3_8.txt,MAC_Bench/Cell/Cover/Joule/6_11.png,MAC_Bench/Cell/Cover/Joule/6_11.png,clip,6_11.txt,MAC_Bench/Cell/Cover/Joule/8_9.png,MAC_Bench/Cell/Cover/Joule/8_9.png,vitg,8_9.txt,test
Trends in Ecology & Evolution,39_3,Which of the following options best describe the cover story?,"In this issue, two articles discuss the use and application of bioacoustic
information. First, on pages 947–960, Elly Knight and colleagues discuss what is
needed to identify individuals in bioacoustic recordings, which have historically
focused on the identification of species. Second, on pages 961–973, William Oestreich
and colleagues discuss how information from bioacoustics recordings can be used
to assess animal behaviour. They argue that because behaviour typically represents
animals’ first response to environmental change, behavioural bioacoustics can provide
insights into animals’ adaptations to global change. The cover shows a black-footed
albatross (Phoebastria nigripes) calling among foraging conspecifics in Monterey Bay,
California, USA. Image credit: William Oestreich.",A,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_3.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_3.png,groundtruth,39_3.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/28_10.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/28_10.png,clip,28_10.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_10.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_10.png,vith,36_10.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_9.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_9.png,vitg,34_9.txt,train
Journal of Chemical Theory and Computation,2024_15,Which of the following options best describe the cover story?,"Carbon monoxide is a serious life threat by binding to hemoglobin and making people suffer from hypoxia. Jiang et.al. construct the classical force field parameters for simulating the coordination interactions among hemoglobin, CO, and O2 as well as reveal the binding strength between hemoglobin and CO in different O2 environments.",A,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_15.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_15.png,groundtruth,2024_15.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,clip,2023_16.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2015_4.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2015_4.png,vith,2015_4.txt,train
ACS Synthetic Biology,2024_3,Which of the following options best describe the cover story?,Engineering living material for fragrance release.  View the article.,D,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_4.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_4.png,vith,2024_4.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,vitg,2025_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2014_7.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2014_7.png,clip,2014_7.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_3.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_3.png,groundtruth,2024_3.txt,train
Trends in Parasitology,40_9,Which of the following options best describe the cover story?,"Non-self-produced compounds from the environment can be consumed
or applied as prophylactic or therapeutic agents to avoid infections or cure diseased
individuals. In this issue of Trends in Parasitology, Erler et al. provide a new view on
animal medication, broadening the current concept of (self-)medication by including
inclusive fi tness, innate immunity and the microbiome. Studying insects (from solitary
to
social communities) offers unique advantages to better understanding the mechanisms
and evolution of animal medication. This cover image shows a bumble bee (Bombus
   hypnorum) foraging for food on a thistle. Bumble bees, as many other insect species,
forage and feed on different plant material and products. Plant secondary metabolites
(found in nectar and pollen) are known to enhance bee health and/or to reduce parasite
loads in infected individuals. Image credit: Silvio Erler.",A,MAC_Bench/Cell/Cover/Trends in Parasitology/40_9.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_9.png,groundtruth,40_9.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/39_7.png,MAC_Bench/Cell/Cover/Trends in Parasitology/39_7.png,vitg,39_7.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/28_3.png,MAC_Bench/Cell/Cover/Trends in Parasitology/28_3.png,vith,28_3.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/35_11.png,MAC_Bench/Cell/Cover/Trends in Parasitology/35_11.png,clip,35_11.txt,train
NATURE MATERIALS,23_5,Which of the following options best describe the cover story?,"Enhanced transport through metallic carbon nanotubes
Extreme confinement of water and ions within nanofluidic channels gives rise to unusual transport phenomena. Here the authors investigate how electronic properties of carbon nanotube porins influence the transport efficiency of water and ions.
See Li et al.
Image: Ella Maru Studio. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_5.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_5.png,groundtruth,23_5.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/10_9.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/10_9.png,vith,10_9.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_12.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_12.png,vitg,23_12.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/14_12.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/14_12.png,clip,14_12.txt,train
Cell Stem Cell,32_2,Which of the following options best describe the cover story?,"On the cover: In this issue, Voit et al. report on the development of a unified gene therapy approach applicable to all patients
with the inherited bone marrow failure syndrome Diamond-Blackfan anemia (DBA). Mutations
in one of more than 30 genes cause erythroid maturation arrest in DBA, but regulated
lentiviral expression of the transcription factor GATA1 exclusively in developing
erythroid progenitors overcomes the erythroid maturation arrest irrespective of causative
gene mutation and improves erythroid output in DBA. The cover image depicts a blood
factory, representative of the bone marrow, with hematopoietic stem cells undergoing
differentiation. Some developing cells commit to erythroid differentiation but are
blocked by a pile of rubble with diamonds and black fans, representing DBA. To overcome
this, factory workers labeled GATA1 are running to help carry the progenitors around
the obstacle, leading to increased production of mature red blood cells. Cover illustrated
by DrawImpacts.",A,MAC_Bench/Cell/Cover/Cell Stem Cell/32_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/32_2.png,groundtruth,32_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/6_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_1.png,vitg,6_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/9_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/9_1.png,vith,9_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/23_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/23_2.png,clip,23_2.txt,train
Nature Biomedical Engineering,8_5,Which of the following options best describe the cover story?,"Softening intravenous insertion
This issue highlights an intravenous needle that softens on insertion, a bilingual speech neuroprosthesis, spinal-cord stimulation for the restoration of sensory feedback in individuals with transtibial amputation, a thermoelectric device for the restoration of thermal perceptions in a phantom hand, nanowire arrays for restoring vision, implantable temperature sensors for monitoring intestinal inflammation, and the recapitulation of neuropathogenesis induced by SARS-CoV-2 in a lung–brain microphysiological system.
The cover illustrates an intravenous needle whose stiffness and shape depend on body temperature so that it can soften on insertion.
See Agno et al.
Image: Karen-Christian Agno, Eun Young Jeong and Jae-Woong Jeong (KAIST), and Younghee Lee. Cover design: Alex Wing.",C,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_3.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_3.png,ave_2,5_3.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/6_7.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/6_7.png,vitg,6_7.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_5.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_5.png,groundtruth,8_5.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_8.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_8.png,clip,4_8.txt,train
Science,387_6730,Which of the following options best describe the cover story?,"COVERAn eastern gray kangaroo (Macropus giganteus) grazes in Yuraygir National Park, New South Wales, Australia. It has long been thought that short-faced kangaroos became extinct in the late Pleistocene because they were specialist browsers, in contrast to long-faced grazing kangaroos, which still thrive today. However, dental microwear patterns show that most Pleistocene kangaroos actually had broad diets—an adaptation to climate-driven fluctuations in vegetation. See page 167.
Photo: Yva Momatiuk and John Eastcott/Minden",B,MAC_Bench/Science/Cover/Science/374_6563.png,MAC_Bench/Science/Cover/Science/374_6563.png,vith,374_6563.txt,MAC_Bench/Science/Cover/Science/387_6730.png,MAC_Bench/Science/Cover/Science/387_6730.png,groundtruth,387_6730.txt,MAC_Bench/Science/Cover/Science/382_6670.png,MAC_Bench/Science/Cover/Science/382_6670.png,vitg,382_6670.txt,MAC_Bench/Science/Cover/Science/338_6113.png,MAC_Bench/Science/Cover/Science/338_6113.png,clip,338_6113.txt,train
Med,5_1,Which of the following options best describe the cover story?,"On the cover: Prostate cancer is a highly heterogeneous disease, making prognosis
and treatment challenging. Interlesional response heterogeneity (ILRH) poses challenges
to the abiraterone treatment of prostate cancer. This variability in drug response
can be likened to musical notes on a staff. Pan et al. used PET/CT imaging to evaluate the ILRH and stratify patients from single pattern
on the left (traditional methods) into distinct response patterns, depicted by three
musical patterns on the right (new approach). This underscores the potential value
of integrating PET/CT imaging into the design of future clinical trials. Cover credit:
Ruozhen Huang.",B,MAC_Bench/Cell/Cover/Med/4_7.png,MAC_Bench/Cell/Cover/Med/4_7.png,vitg,4_7.txt,MAC_Bench/Cell/Cover/Med/5_1.png,MAC_Bench/Cell/Cover/Med/5_1.png,groundtruth,5_1.txt,MAC_Bench/Cell/Cover/Med/5_9.png,MAC_Bench/Cell/Cover/Med/5_9.png,vith,5_9.txt,MAC_Bench/Cell/Cover/Med/5_5.png,MAC_Bench/Cell/Cover/Med/5_5.png,clip,5_5.txt,val
Nature Reviews Cardiology,21_7,Which of the following options best describe the cover story?,"RNA-binding proteins: the beat goes on, inspired by the Review on p361.
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_5.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_5.png,ave_1,19_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_7.png,groundtruth,21_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,vitg,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_11.png,clip,20_11.txt,train
NATURE ENERGY,9_2,Which of the following options best describe the cover story?,"Battery longevity from new datasets
The demand for public datasets in battery research is growing as the need for transparent analyses of battery health increases. Jan Figgener and colleagues address this need through an extensive eight-year study of twenty-one lithium-ion battery systems, providing valuable insights into longevity for home storage applications.
See Figgener et al.
Image: CARL RWTH Aachen University. Cover Design: Alex Wing.",A,MAC_Bench/Nature/Cover/NATURE ENERGY/9_2.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_2.png,groundtruth,9_2.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/6_1.png,MAC_Bench/Nature/Cover/NATURE ENERGY/6_1.png,ave_3,6_1.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/8_2.png,MAC_Bench/Nature/Cover/NATURE ENERGY/8_2.png,ave_2,8_2.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/4_8.png,MAC_Bench/Nature/Cover/NATURE ENERGY/4_8.png,clip,4_8.txt,train
Trends in Genetics,41_1,Which of the following options best describe the cover story?,"Sex chromosomes can cause expression imbalances between males
and females that are often corrected through dosage compensation. In this issue,
Kalita and Keller Valsecchi review our current understanding of dosage compensation
across diverse insect species beyond traditional model organisms. They discuss the
evolutionary dynamics of sex chromosomes, the variety of molecular mechanisms that
achieve balanced expression, and propose approaches to uncover regulatory pathways
in non-model insects. Illustration by Agata Kalita.",B,MAC_Bench/Cell/Cover/Trends in Genetics/39_6.png,MAC_Bench/Cell/Cover/Trends in Genetics/39_6.png,ave_3,39_6.txt,MAC_Bench/Cell/Cover/Trends in Genetics/41_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/41_1.png,groundtruth,41_1.txt,MAC_Bench/Cell/Cover/Trends in Genetics/35_9.png,MAC_Bench/Cell/Cover/Trends in Genetics/35_9.png,clip,35_9.txt,MAC_Bench/Cell/Cover/Trends in Genetics/41_3.png,MAC_Bench/Cell/Cover/Trends in Genetics/41_3.png,vitg,41_3.txt,train
Structure,32_7,Which of the following options best describe the cover story?,"On the cover: In this piece, a flower garden provides a metaphor for the creation
and growth of designed protein assemblies. Meador et al. describe machine learning algorithms that greatly expand the ability to generate
new types of protein-based molecular cages, whose beauty and diversity are reminiscent
of natural flora. Image credit: Nika Gladkov.",D,MAC_Bench/Cell/Cover/Structure/26_10.png,MAC_Bench/Cell/Cover/Structure/26_10.png,vith,26_10.txt,MAC_Bench/Cell/Cover/Structure/27_2.png,MAC_Bench/Cell/Cover/Structure/27_2.png,vitg,27_2.txt,MAC_Bench/Cell/Cover/Structure/30_11.png,MAC_Bench/Cell/Cover/Structure/30_11.png,clip,30_11.txt,MAC_Bench/Cell/Cover/Structure/32_7.png,MAC_Bench/Cell/Cover/Structure/32_7.png,groundtruth,32_7.txt,train
Nature Plants,10_12,Which of the following options best describe the cover story?,"Passing on protection
Developing embryos are supplied with maternally produced compounds, including glucosinolate defence compounds. To cross the four intervening cellular barriers requires plasma membrane-located exporters (such as UMAMIT29, labelled in green) and importers in maternal and embryonic tissues.
See Sanden et al.
Image: Niels Christian Holm Sanden, University of Copenhagen. Cover Design: Erin Dewalt.",B,MAC_Bench/Nature/Cover/Nature Plants/7_3.png,MAC_Bench/Nature/Cover/Nature Plants/7_3.png,clip,7_3.txt,MAC_Bench/Nature/Cover/Nature Plants/10_12.png,MAC_Bench/Nature/Cover/Nature Plants/10_12.png,groundtruth,10_12.txt,MAC_Bench/Nature/Cover/Nature Plants/7_2.png,MAC_Bench/Nature/Cover/Nature Plants/7_2.png,ave_1,7_2.txt,MAC_Bench/Nature/Cover/Nature Plants/7_12.png,MAC_Bench/Nature/Cover/Nature Plants/7_12.png,vith,7_12.txt,val
Nature Reviews Clinical Oncology,21_2,Which of the following options best describe the cover story?,"The road travelled and challenges ahead in clinical oncology, inspired by the Viewpoint on p771.
Cover design: Carl Conway",A,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_2.png,groundtruth,21_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_6.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_6.png,clip,19_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_5.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_5.png,vitg,18_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_4.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_4.png,ave_2,19_4.txt,val
Nature Synthesis,3_9,Which of the following options best describe the cover story?,"Mixing immiscible metals
The synthesis of coordination-controlled metal alloys is reported using a metallurgy-based alloy design and subsequent de-alloying process. The metallurgical alloy catalysts enable the control of metal active sites and steer CO2 electroreduction towards hydrocarbon or oxygenate production.
See Kim et al.
Image: Younghee Lee/CUBE3D Graphic. Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,vitg,1_8.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,groundtruth,3_9.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,ave_3,2_6.txt,test
Nature Reviews Earth & Environment,5_7,Which of the following options best describe the cover story?,"Increasing light emissions threaten human and ecological health. This Review outlines existing measurements and projections of light pollution trends and impacts, as well as developments in ground-based and remote sensing techniques that are needed to improve them.
Image credit: Dneutral Han/Getty images. Cover design: Carl Conway.",B,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_2.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_7.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_7.png,groundtruth,5_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_7.png,ave_1,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_12.png,vitg,1_12.txt,train
BDJ,237_11,Which of the following options best describe the cover story?,"In this issue
This issue features articles on dental trauma, short dental implants, and climate-conscious sedation.

Cover image: From 2007. For this issue, the cover used as its inspiration is that by Joe Dixon (taken from Volume 202 Issue 10, 26 May 2007). Our thinking at the time was to build on these early foundations of the coalescence of art and science in dentistry. In this new interpretation, we have zoomed out to illustrate the practical interaction of the microscope, the researcher and the clinical relevance.
©Tim Marrs, incorporating original cover art by Joe Dixon",C,MAC_Bench/Nature/Cover/BDJ/228_3.png,MAC_Bench/Nature/Cover/BDJ/228_3.png,vitg,228_3.txt,MAC_Bench/Nature/Cover/BDJ/237_5.png,MAC_Bench/Nature/Cover/BDJ/237_5.png,vith,237_5.txt,MAC_Bench/Nature/Cover/BDJ/237_11.png,MAC_Bench/Nature/Cover/BDJ/237_11.png,groundtruth,237_11.txt,MAC_Bench/Nature/Cover/BDJ/228_4.png,MAC_Bench/Nature/Cover/BDJ/228_4.png,clip,228_4.txt,train
Nature Cities,1_7,Which of the following options best describe the cover story?,"Urbanization warming Indian cities
In a context of rapid industrialization, urbanization and climate change, Indian cities have experienced increasing warming. About 60% of the increased temperatures come from urbanization alone, especially in medium-sized cities.
See Sethi & Vinoj
Image: Dr. Vinoj. V, Indian Institute of Technology Bhubaneswar, INDIA. Cover design: Lauren Heslop",D,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,ave_3,1_11.txt,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,clip,1_3.txt,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,ave_2,1_5.txt,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,MAC_Bench/Nature/Cover/Nature Cities/1_7.png,groundtruth,1_7.txt,train
Cell Chemical Biology,31_14,Which of the following options best describe the cover story?,"On the cover: Rana et al. develop the proteolysis targeting chimera (PROTAC) Versortrexate (VSTX), shown in
the foreground, as a composite molecule of the antifolate methotrexate (red) and the
E3 ligase-targeting small-molecule thalidomide (blue). Once VSTX engages dihydrofolate
reductase (DHFR) (foreground), it catalyzes DHFR’s proteasome-dependent degradation,
depicted as disintegrating images of DHFR. Artwork designed by Darryl Leja and James
Inglese.",B,MAC_Bench/Cell/Cover/Cell Chemical Biology/22_4.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/22_4.png,clip,22_4.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_14.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_14.png,groundtruth,31_14.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/20_9.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/20_9.png,vith,20_9.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_10.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_10.png,ave_1,19_10.txt,train
Caner Cell,42_8,Which of the following options best describe the cover story?,"On the cover: Dyikanov et al. develop a machine learning platform that classifies a patient’s immune system into
five immunotypes using a blood test. On the cover, the railway map represents these
immunotypes as train stations with distinct characteristics. G1-naive and G2-primed,
characteristic of immune systems with the greatest potential to respond to immunogenic
stimuli, are represented by a fertile, green landscape. G3-progressive is a transitional
immunotype represented by a central hub. The G4-chronic station is a heavily developed
urban landscape, symbolizing an immune system shaped by persistent activation and
chronic antigen exposure. G5-suppressive is a desert that represents a depleted immune
system. The trains ferry passengers among different stations along the railway lines,
symbolizing the dynamic nature of one’s immunotype depending on their health or disease
status. (Image credit: Alfiia Mustafina).",D,MAC_Bench/Cell/Cover/Caner Cell/16_6.png,MAC_Bench/Cell/Cover/Caner Cell/16_6.png,vith,16_6.txt,MAC_Bench/Cell/Cover/Caner Cell/39_7.png,MAC_Bench/Cell/Cover/Caner Cell/39_7.png,vitg,39_7.txt,MAC_Bench/Cell/Cover/Caner Cell/28_2.png,MAC_Bench/Cell/Cover/Caner Cell/28_2.png,clip,28_2.txt,MAC_Bench/Cell/Cover/Caner Cell/42_8.png,MAC_Bench/Cell/Cover/Caner Cell/42_8.png,groundtruth,42_8.txt,val
ACS Central Science,2024_9,Which of the following options best describe the cover story?,"A layer-blocked covalent organic framework (LB-COF) heterogenous film, synthesized via two successive surface-initiated polycondensations, shared superior photocatalytic uranium extraction performance as a result of the formation of a S-scheme heterojunction.",B,MAC_Bench/ACS/Cover/ACS Central Science/2023_12.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_12.png,vitg,2023_12.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_9.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_4.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,vith,2025_2.txt,test
Developmental Cell,59_5,Which of the following options best describe the cover story?,"On the cover: The cover features a set of fluorescence microscopy images of the keratin
intermediate filament cytoskeleton network, which provides mechanical strength to
epithelial cells. The different image colors represent the many different mixtures
of keratin isoforms expressed depending on the cellular context. Images from different
time points are superimposed, providing a sense of motion. The blue and yellow panel
traces the filament paths, emphasizing their mesh-like network configuration. To learn
more about how different keratin isoforms influence epithelial cell behavior, see
Nanes et al. Image credit: Benjamin Nanes.",C,MAC_Bench/Cell/Cover/Developmental Cell/22_4.png,MAC_Bench/Cell/Cover/Developmental Cell/22_4.png,vith,22_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/36_3.png,MAC_Bench/Cell/Cover/Developmental Cell/36_3.png,vitg,36_3.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_5.png,MAC_Bench/Cell/Cover/Developmental Cell/59_5.png,groundtruth,59_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/56_23.png,MAC_Bench/Cell/Cover/Developmental Cell/56_23.png,clip,56_23.txt,train
Trends in Endocrinology & Metabolism,35_1,Which of the following options best describe the cover story?,"Since Warburg's time, it has been recognized that iron is essential for
metabolism. But how do cells utilize this versatile biometal? In this issue, Teh et al.
offer an exploration of iron's diverse roles, spanning cellular biochemistry to clinical
pathology. The cover illustrates the authors' goal to provide contemporary insights—
symbolized by a laptop on a lectern showcasing iron trafficking—into enduring
questions, represented by a gothic library adorned with iron-themed stained glass
and
ancient books. Cover credit: Sonhita Chakraborty (www.artbysonhita.com/)",D,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/31_7.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/31_7.png,vitg,31_7.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_1.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_1.png,vith,25_1.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,clip,27_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_1.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_1.png,groundtruth,35_1.txt,train
Nature Protocols,19_4,Which of the following options best describe the cover story?,"Microfluidic system to isolate neuronal compartments
Neurons of the dorsal root ganglia grow along channels of microfluidic chambers. This enables the isolation and subsequent study of membrane protein dynamics in discrete neuronal somas (orange) and axons (blue). See Tyagi et al.
Image: Elizabeth Akin, Grant Higerd-Rusli and Sidharth Tyagi, Yale University. Cover design: S. Whitham",D,MAC_Bench/Nature/Cover/Nature Protocols/17_12.png,MAC_Bench/Nature/Cover/Nature Protocols/17_12.png,vith,17_12.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_8.png,MAC_Bench/Nature/Cover/Nature Protocols/15_8.png,vitg,15_8.txt,MAC_Bench/Nature/Cover/Nature Protocols/13_4.png,MAC_Bench/Nature/Cover/Nature Protocols/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_4.png,MAC_Bench/Nature/Cover/Nature Protocols/19_4.png,groundtruth,19_4.txt,train
Nature Reviews Bioengineering,2_6,Which of the following options best describe the cover story?,"Soft bioelectronic systems can be interfaced with the body for the monitoring of human health and disease. However, motion artefacts caused by body movements or physiological activities can affect signal detection and interpretation in bioelectronic measurements, which can be addressed by various motion artefact management strategies. See Junyi Yin et al.
Cover image: Jun Chen. Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_5.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,clip,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_5.png,ave_1,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_6.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_6.png,groundtruth,2_6.txt,train
Molecular Therapy,32_14,Which of the following options best describe the cover story?,"On the cover: Scanning electron micrograph of the sound mechano-sensitive hair bundle, a key target
for Clarin-2-mediated therapeutics to preserve audition. Mendia and colleagues demonstrate successful maintenance of hearing through AAV gene delivery to the inner
ear. Image credit: Sandrine Vitry and Jean-Marc Panaud.",C,MAC_Bench/Cell/Cover/Molecular Therapy/31_1.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_1.png,clip,31_1.txt,MAC_Bench/Cell/Cover/Molecular Therapy/25_12.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_12.png,vith,25_12.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_14.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_14.png,groundtruth,32_14.txt,MAC_Bench/Cell/Cover/Molecular Therapy/30_5.png,MAC_Bench/Cell/Cover/Molecular Therapy/30_5.png,vitg,30_5.txt,val
Nature Biomedical Engineering,8_4,Which of the following options best describe the cover story?,"Bacteria and neutrophil extracellular traps drive dental calculi
This issue highlights a near-infrared dye for fluorescence-guided tumour resection and the assessment of wound healing, an inexpensive light-sheet fluorescence microscope for the high-resolution imaging of cleared and living samples at scale, transient pacing in pigs with complete heart block via myocardial injection of mRNA coding for a transcription factor, an analysis of neuroimaging data across mental health, neurodegenerative, psychiatric and neurodevelopmental diagnostic categories, that blocking the mechanical sensor PIEZO1 in cytotoxic T lymphocytes augments their cytotoxicity against tumour cells, and that bacteria-mediated resistance of neutrophil extracellular traps to enzymatic degradation drives the formation of dental calculi.
The cover illustrates that the development of dental calculi involves bacteria in local mature biofilms converting the DNA in neutrophil extracellular traps from being degradable by the enzyme DNase I to being degradation-resistant.
See Wan et al.
Image: Mei-chen Wan, The Fourth Military Medical University. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/3_1.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/3_1.png,clip,3_1.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_4.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_4.png,groundtruth,8_4.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_12.png,vith,4_12.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_7.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_7.png,vitg,8_7.txt,train
ACS Energy Letters,2024_8,Which of the following options best describe the cover story?,Rotations of MA cations with large dipole moments significantly reduce the thermal conductivity by scattering acoustic phonons,C,MAC_Bench/ACS/Cover/ACS Energy Letters/2020_1.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2020_1.png,vith,2020_1.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2018_7.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2018_7.png,clip,2018_7.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_8.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2025_2.png,vitg,2025_2.txt,train
NATURE BIOTECHNOLOGY,42_12,Which of the following options best describe the cover story?,"Multi-immersion mirror objectives
Neurons in the mouse hippocampus imaged with the Schmidt objective. Voigt et al. develop a multi-immersion objective based on a mirror instead of a lens.
See Voigt et al.
Image: Anna Maria Reuss and Fabian Voigt. Cover design: Erin Dewalt.",D,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/37_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/37_4.png,ave_2,37_4.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_1.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_1.png,clip,39_1.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/36_3.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/36_3.png,vith,36_3.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_12.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_12.png,groundtruth,42_12.txt,val
Journal of the American Chemical Society,2025_8,Which of the following options best describe the cover story?,Reporting high-entropy two-dimensional layered double hydroxide (HE-LDH) nanoplatforms with versatile physicochemical advantages that reprogram the tumor microenvironment (TME) and provide antitumor treatment via cascaded nanoenzyme-initiated chemodynamic and immune synergistic therapy.,A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2025_8.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2025_8.png,groundtruth,2025_8.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2014_34.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2014_34.png,vith,2014_34.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_28.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2023_28.png,vitg,2023_28.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_36.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2019_36.png,clip,2019_36.txt,train
Macromolecules,2024_22,Which of the following options best describe the cover story?,"Synthesis and application of branched polymers are like the root and fruit of a tree. The stronger the root of a tree, the higher the amount of fruit.",A,MAC_Bench/ACS/Cover/Macromolecules/2024_22.png,MAC_Bench/ACS/Cover/Macromolecules/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_15.png,MAC_Bench/ACS/Cover/Macromolecules/2010_15.png,clip,2010_15.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_11.png,MAC_Bench/ACS/Cover/Macromolecules/2014_11.png,vith,2014_11.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_12.png,MAC_Bench/ACS/Cover/Macromolecules/2012_12.png,vitg,2012_12.txt,val
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,22_1,Which of the following options best describe the cover story?,"Diet and intestinal stem cells, inspired by the Review on p23
Cover design: Neil Smith",B,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_10.png,clip,18_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_1.png,groundtruth,22_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_2.png,vith,22_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.png,vitg,20_4.txt,train
Nature Cardiovascular Research,3_7,Which of the following options best describe the cover story?,"Explaining heart failure
Fernandez-Patron et al. propose a unifying framework explaining how diverse risk factors such as hypertension, obesity and diabetes lead to the pathogenesis and progression of heart failure.
See Fernandez-Patron et al.
Image: Eugenio Hardy, Center for Molecular Immunology, Cuba and Carlos Fernandez-Patron, University of Alberta, Canada. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_12.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_12.png,vith,1_12.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_1.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_1.png,vitg,3_1.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_7.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_7.png,groundtruth,3_7.txt,train
ACS Food Science & Technology,2025_1,Which of the following options best describe the cover story?,Purple tomatoes (available in the USA) on a background of red and yellow snaking tomatoes. Photograph Eugenio Butelli and Phil Robison.,C,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,ave_1,2023_2.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_1.png,ave_2,2023_1.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2025_1.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2025_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2025_2.png,clip,2025_2.txt,val
Macromolecules,2025_3,Which of the following options best describe the cover story?,Schematic illustration of the mechanical characterization of nanocomposite materials by atomic force microscopy and the modulus–,C,MAC_Bench/ACS/Cover/Macromolecules/2011_18.png,MAC_Bench/ACS/Cover/Macromolecules/2011_18.png,clip,2011_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_5.png,MAC_Bench/ACS/Cover/Macromolecules/2024_5.png,vith,2024_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2025_3.png,MAC_Bench/ACS/Cover/Macromolecules/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_3.png,MAC_Bench/ACS/Cover/Macromolecules/2010_3.png,vitg,2010_3.txt,train
BDJ In Practice,37_11,Which of the following options best describe the cover story?,"Volume 37 | Issue 2 | February
In this issue we ask three industry experts about the art of leadership in dentistry. Check out our cover feature to see what they say!
Cover illustration by Tim Marrs",A,MAC_Bench/Nature/Cover/BDJ In Practice/37_11.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_11.png,groundtruth,37_11.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,clip,35_8.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_9.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_9.png,ave_2,35_9.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,vith,37_2.txt,train
Nature Reviews Neurology,20_3,Which of the following options best describe the cover story?,"Spectrum of disease, inspired by the Review on p602.
Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,vith,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_3.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_3.png,groundtruth,20_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_5.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_5.png,clip,20_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/19_7.png,vitg,19_7.txt,val
Macromolecules,2024_3,Which of the following options best describe the cover story?,Hydrodynamic simulations show that liquid flow has two opposing effects on the speed at which the volume of a nanogel particle changes during collapse and expansion. View the article.,C,MAC_Bench/ACS/Cover/Macromolecules/2022_6.png,MAC_Bench/ACS/Cover/Macromolecules/2022_6.png,ave_1,2022_6.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_9.png,MAC_Bench/ACS/Cover/Macromolecules/2022_9.png,clip,2022_9.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_3.png,MAC_Bench/ACS/Cover/Macromolecules/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_23.png,MAC_Bench/ACS/Cover/Macromolecules/2014_23.png,vitg,2014_23.txt,train
Nature Reviews Bioengineering,2_10,Which of the following options best describe the cover story?,"Nanoparticles can be systemically injected into the body for cancer diagnosis and treatment. Active transport mechanisms may enable nanoparticles to enter the tumour through active endothelial transport processes, retain in the tumour owing to interactions with tumour components, and exit the tumour through lymphatic vessels. See Luan N.M. Nguyen et al.
Cover image: Matthew Nguyen. Cover design: Simon Bradbrook.",D,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/3_1.png,clip,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/1_10.png,ave_2,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_2.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_2.png,vith,2_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_10.png,MAC_Bench/Nature/Cover/Nature Reviews Bioengineering/2_10.png,groundtruth,2_10.txt,train
Trends in Chemistry,6_14,Which of the following options best describe the cover story?,"Automation in chemical research fosters innovation and efficiency but
introduces a critical dilemma—selecting the appropriate development approach for
automated platforms. This decision involves choosing between fixed automation,
known for specialized setups, and flexible automation, valued for its adaptability.
In their
Forum article, Hein et al. offer an introductory guide to the decision-making process in
adopting automation platforms. The article conducts a comparative analysis of fixed
and flexible automation, providing insights for researchers navigating the intricate
landscape of deploying automated platforms. Image Credit: Tyler R. Donnelly and Rama
El-khawaldeh.",C,MAC_Bench/Cell/Cover/Trends in Chemistry/3_11.png,MAC_Bench/Cell/Cover/Trends in Chemistry/3_11.png,ave_2,3_11.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/2_13.png,MAC_Bench/Cell/Cover/Trends in Chemistry/2_13.png,clip,2_13.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_14.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_14.png,groundtruth,6_14.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/3_12.png,MAC_Bench/Cell/Cover/Trends in Chemistry/3_12.png,vitg,3_12.txt,train
NATURE MEDICINE,30_12,Which of the following options best describe the cover story?,"Series on Women’s Health
In this issue, Nature Medicine launches a Series on Women’s Health throughout the life course. Women’s health remains underserved by the medical research community, and the impacts of sex differences and sociocultural factors on the health and wellbeing of women are rarely considered. The first installment of this Series presents a Perspective calling for a life-course approach to the prevention and treatment of non-communicable diseases in women.
See Series
Image: Marina Spence. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_11.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_11.png,clip,30_11.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/17_4.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/17_4.png,vith,17_4.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_1.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/25_1.png,ave_1,25_1.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_12.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_12.png,groundtruth,30_12.txt,train
Lab Animal,53_4,Which of the following options best describe the cover story?,"Exon-skipping gene editing in marmoset
Many disease-related genes cause perinatal death in genetically altered homozygous nonhuman primates (NHP). As NHP resources are limited, efficient methods are necessary to create new genetic models. In a new Article, Sasaki et al. show that using Platinum TALEN gene-editing technology in oocytes is an effective method for producing genetically modified heterozygous marmosets by exon skipping.
See Sato et al.
Cover image: Perception7 / iStock / Getty Images Plus and Marina Spence. Cover design: Marina Spence.",B,MAC_Bench/Nature/Cover/Lab Animal/51_4.png,MAC_Bench/Nature/Cover/Lab Animal/51_4.png,vitg,51_4.txt,MAC_Bench/Nature/Cover/Lab Animal/53_4.png,MAC_Bench/Nature/Cover/Lab Animal/53_4.png,groundtruth,53_4.txt,MAC_Bench/Nature/Cover/Lab Animal/49_9.png,MAC_Bench/Nature/Cover/Lab Animal/49_9.png,ave_3,49_9.txt,MAC_Bench/Nature/Cover/Lab Animal/48_10.png,MAC_Bench/Nature/Cover/Lab Animal/48_10.png,clip,48_10.txt,test
Trends in Plant Science,29_13,Which of the following options best describe the cover story?,"The Nobel Prize in Chemistry for 2022 was awarded to the pioneers of
Lego-like ‘click chemistry’ – combinatorial chemistry with remarkable modularity and
diversity. It has been applied to a wide variety of biological systems, from microorganisms
to plants and animals, including humans. Ming-Ming Chen, Peng Wang and colleagues
review click chemistry reactions and their applications in plant systems to visualize
plant
biological processes. Click chemistry is one of an array of modern tools highlighted
in
this special issue that offer new opportunities to explore and understand the underlying
molecular mechanisms of many biological processes in plants, as well as finding
applications in agriculture for delivering smart crops fit for the 21st century. Image
credit:
Ming-Ming Chen.",B,MAC_Bench/Cell/Cover/Trends in Plant Science/15_12.png,MAC_Bench/Cell/Cover/Trends in Plant Science/15_12.png,vitg,15_12.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_13.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_13.png,groundtruth,29_13.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_12.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_12.png,vith,29_12.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/17_6.png,MAC_Bench/Cell/Cover/Trends in Plant Science/17_6.png,clip,17_6.txt,train
Nature Reviews Materials,9_11,Which of the following options best describe the cover story?,"Bioinspired electronics made of soft electrochemical matter based on organic mixed conductors can enable the integration of diverse forms of intelligence into everyday life. The cover image shows an artist’s impression of synapses communicating with an electronic device. See >Gkoupidenis P. et al
Cover image: Sam Whitham",B,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_4.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_4.png,ave_2,5_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_11.png,groundtruth,9_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_10.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_10.png,clip,7_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_10.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_10.png,vitg,8_10.txt,train
Nature Machine Intelligence,6_4,Which of the following options best describe the cover story?,"Fly-by-feel flight control
Natural flight capabilities surpass current drone technology, with mechanoreceptors in wings thought to have a crucial role in the control of insect flight. Inspired by this observation, Kim et al. developed a wing strain-based control system, achieving precise manoeuvrability of flapping wing robots and offering insights into autonomous flight control within complex aerodynamic flows.
See Kim et al.
Image: Aleksey Akimov/ Shutterstock. Pixacon/ Shutterstock. 3d_molier International/ Turboquid by Shutterstock. Image concept: Daeshik Kang, Ajou University. Cover design: Vanitha Selvarajan",A,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_4.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_4.png,groundtruth,6_4.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_12.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_12.png,clip,3_12.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_7.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_7.png,ave_2,3_7.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_12.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_12.png,vitg,5_12.txt,train
Immunity,58_1,Which of the following options best describe the cover story?,"On the cover: Inpp5d, a risk gene for Alzheimer’s disease, encodes the lipid phosphatase SHIP1. Matera, Compagnion, et al. demonstrate that Inpp5d is expressed in microglia during early postnatal brain development, where it limits
synaptic pruning in a complement-dependent manner. Perturbation of Inpp5d during brain development has long-lasting effects on cognitive function. The cover
image depicts microglial cells (magenta) interacting with neurons (cyan) in the mouse
CA1 hippocampal region during early development, specifically at postnatal day 15.
The plasticity and dynamism of microglia, which constantly scan the brain environment,
are highlighted by oil painting effect. Image acquisition and editing by Alessandro
Matera.",C,MAC_Bench/Cell/Cover/Immunity/42_5.png,MAC_Bench/Cell/Cover/Immunity/42_5.png,vith,42_5.txt,MAC_Bench/Cell/Cover/Immunity/36_6.png,MAC_Bench/Cell/Cover/Immunity/36_6.png,vitg,36_6.txt,MAC_Bench/Cell/Cover/Immunity/58_1.png,MAC_Bench/Cell/Cover/Immunity/58_1.png,groundtruth,58_1.txt,MAC_Bench/Cell/Cover/Immunity/57_4.png,MAC_Bench/Cell/Cover/Immunity/57_4.png,clip,57_4.txt,test
Nature Machine Intelligence,6_11,Which of the following options best describe the cover story?,"Dynamic biomolecular complex prediction with generative AI
Predicting the structure of 3D biological binding complexes is a major challenge in structural biology. Qiao et al. report a diffusion model-based generative AI approach known as NeuralPLexer that enables the prediction of protein–ligand structures, including large-scale conformational changes of such structures after ligand binding, based on protein sequences and ligand molecular graphs. The methodology could advance the mechanistic understanding of biological pathways and aid the discovery of new therapeutic agents.
See Qiao et al.
Image: Frederick R. Manby and Matthew Welborn. Cover design: Amie Fernandez",A,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_11.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_11.png,groundtruth,6_11.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_11.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_11.png,ave_2,5_11.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_9.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_9.png,vitg,6_9.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_1.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_1.png,clip,3_1.txt,train
Nature Computational Science,4_11,Which of the following options best describe the cover story?,"Inferring algorithms from data
Data-driven discovery of algorithms is an important task for uncovering the underlying logic and rules behind experimental data and can be potentially used by researchers for generating new insights hidden in high-dimensional data. In this issue, Milo M. Lin et al. introduce an approach that makes use of a neurobiologically inspired deep learning algorithm for writing interpretable and executable computer code from data. The method is able to discover algorithms that perform very similarly to or that outperform human-designed ones. The cover image depicts source code that was transformed into an image featuring bands and gaps, similar to a DNA autoradiogram.
See Milo M. Lin et al. and Joseph Bakarji
Image: WEB2DNA-BAEKDAL.COM / SCIENCE PHOTO LIBRARY. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Computational Science/4_3.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_3.png,ave_1,4_3.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_6.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_6.png,clip,4_6.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_11.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_11.png,groundtruth,4_11.txt,MAC_Bench/Nature/Cover/Nature Computational Science/2_8.png,MAC_Bench/Nature/Cover/Nature Computational Science/2_8.png,vitg,2_8.txt,val
Nature Geoscience,17_2,Which of the following options best describe the cover story?,"Ocean eddy hotspots of nitrogen fixation
: Nitrogen fixation by diazotrophs near the edges of North Atlantic eddies is a key component of the North Atlantic marine nitrogen cycle, according to an analysis of genetic and past eddy activity data. The satellite image, taken on 9 March 2016, shows the Gulf Stream moving across a turbulent North Atlantic Ocean where turbulence is made visible by pigmented phytoplankton.
See Hoerstmann et al.
Image: NASA Ocean Biology Distributed Active Archive Center (OB.DAAC). Cover design: Alex Wing",B,MAC_Bench/Nature/Cover/Nature Geoscience/1_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_2.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_2.png,groundtruth,17_2.txt,MAC_Bench/Nature/Cover/Nature Geoscience/9_6.png,MAC_Bench/Nature/Cover/Nature Geoscience/9_6.png,vith,9_6.txt,MAC_Bench/Nature/Cover/Nature Geoscience/7_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/7_1.png,vitg,7_1.txt,train
NATURE ENERGY,9_6,Which of the following options best describe the cover story?,"Getting flexible
Flexible organic photovoltaic modules suffer from poor operational and mechanical stability. Lu et al. embed the metal electrode into a polymeric matrix and add a chromium layer to enhance the electrical contact between adjacent subcells. This results in 14%-efficient modules with over 900 hours of operation and improved tolerance to bending.
See Lu et al. and News and Views by Shin and Son
Image: Xin Lu, Huazhong University of Science and Technology. Cover design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/NATURE ENERGY/9_6.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_6.png,groundtruth,9_6.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/2_9.png,MAC_Bench/Nature/Cover/NATURE ENERGY/2_9.png,clip,2_9.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/4_2.png,MAC_Bench/Nature/Cover/NATURE ENERGY/4_2.png,vith,4_2.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/6_9.png,MAC_Bench/Nature/Cover/NATURE ENERGY/6_9.png,ave_2,6_9.txt,train
Nature Climate Change,14_11,Which of the following options best describe the cover story?,"Spider web structures shift
How behavioural plasticity can allow species to adapt to global warming remains poorly documented. Writing in this issue, Sun and colleagues find that spiders alter the mesh size of their webs to adjust to changes in prey size spectra following experimental warming.
See Hu et al. and News & Views by Vandegehuchte
Image: Sonal Kulkarni / 500px/500px/Getty. Cover design: Valentina Monaco",A,MAC_Bench/Nature/Cover/Nature Climate Change/14_11.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_11.png,groundtruth,14_11.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_10.png,vitg,14_10.txt,MAC_Bench/Nature/Cover/Nature Climate Change/12_10.png,MAC_Bench/Nature/Cover/Nature Climate Change/12_10.png,clip,12_10.txt,MAC_Bench/Nature/Cover/Nature Climate Change/10_11.png,MAC_Bench/Nature/Cover/Nature Climate Change/10_11.png,ave_1,10_11.txt,test
ACS Agricultural Science & Technology,2024_11,Which of the following options best describe the cover story?,"As shown in our cover, different light intensities have different effects on rice, and medium light intensity can obviously prevent chlorosis of rice. This is of great importance for the factory cultivation of rice seedlings.",A,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_11.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_3.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_3.png,clip,2022_3.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_6.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_6.png,vith,2022_6.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_5.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_5.png,ave_3,2024_5.txt,train
Immunity,57_8,Which of the following options best describe the cover story?,"On the cover: Immune systems exhibit marked differences at baseline in the human population.
In this issue, Mulè et al. introduce the concept of a “naturally adjuvanted” baseline immune setpoint. The authors
use a statistical framework for integrating human population and single-cell variations
in response to influenza vaccines and find that at baseline—before vaccination—innate
immune cell subsets in high responders to an unadjuvanted vaccine phenocopy cell states
uniquely induced by vaccines formulated with the adjuvant AS03. The state of individual
immune systems is illustrated as leaves. Past encounters with caterpillars shape each
leaf, akin to how past exposures and environmental inputs shape immune systems. Amidst
these variations, vividly colored leaves represent individuals who exhibit a shared
naturally adjuvanted immune setpoint, whereas grey leaves represent those less poised
to respond. Artwork by Sarah Hopkins.",C,MAC_Bench/Cell/Cover/Immunity/38_6.png,MAC_Bench/Cell/Cover/Immunity/38_6.png,vith,38_6.txt,MAC_Bench/Cell/Cover/Immunity/52_4.png,MAC_Bench/Cell/Cover/Immunity/52_4.png,vitg,52_4.txt,MAC_Bench/Cell/Cover/Immunity/57_8.png,MAC_Bench/Cell/Cover/Immunity/57_8.png,groundtruth,57_8.txt,MAC_Bench/Cell/Cover/Immunity/40_4.png,MAC_Bench/Cell/Cover/Immunity/40_4.png,clip,40_4.txt,train
Nature Chemistry,16_8,Which of the following options best describe the cover story?,"Monitoring the structural dynamics of MOF crystals
Serial femtosecond crystallography (SFX) is a powerful technique for monitoring structural transformations in crystalline samples, but its use has so far been limited to the study of biological systems. Now, Ihee and co-workers have shown that this technique can be applied to synthetic materials. Specifically, they collected time-resolved SFX data to visualize light-initiated structural dynamics in metal–organic framework single crystals at the atomic level. The cover shows an artistic representation of the metal–organic framework being irradiated by the laser during a serial crystallography measurement.
See Ihee et al.
Image: Younghee Lee/CUBE3D Graphic. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Chemistry/4_11.png,MAC_Bench/Nature/Cover/Nature Chemistry/4_11.png,clip,4_11.txt,MAC_Bench/Nature/Cover/Nature Chemistry/8_9.png,MAC_Bench/Nature/Cover/Nature Chemistry/8_9.png,vitg,8_9.txt,MAC_Bench/Nature/Cover/Nature Chemistry/10_3.png,MAC_Bench/Nature/Cover/Nature Chemistry/10_3.png,vith,10_3.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_8.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_8.png,groundtruth,16_8.txt,val
Nature Reviews Cardiology,21_10,Which of the following options best describe the cover story?,"Sex and ethnicity differences in MINOCA, inspired by the Review on p192.
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_3.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_3.png,ave_1,20_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_10.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_10.png,groundtruth,21_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_12.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_12.png,clip,20_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,vitg,20_10.txt,val
Nature Reviews Neurology,21_1,Which of the following options best describe the cover story?,"Brain diet, inspired by the Review on p5
Cover design: Amie Fernandez",D,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,ave_2,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_2.png,clip,21_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_11.png,ave_3,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_1.png,groundtruth,21_1.txt,train
Cell Systems,15_2,Which of the following options best describe the cover story?,"On the cover: Four predicted ligand-receptor interactions using AlphaFold2, demonstrating
accuracy and structural resolution in identifying binding interfaces. In this issue
of Cell Systems, Danneskiold-Samsøe et al. introduce an approach leveraging AlphaFold2 for predicting ligand-receptor pairs.
Image credit: the authors.",A,MAC_Bench/Cell/Cover/Cell Systems/15_2.png,MAC_Bench/Cell/Cover/Cell Systems/15_2.png,groundtruth,15_2.txt,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,vitg,4_4.txt,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,clip,1_5.txt,MAC_Bench/Cell/Cover/Cell Systems/4_1.png,MAC_Bench/Cell/Cover/Cell Systems/4_1.png,vith,4_1.txt,train
ACS Chemical Biology,2025_1,Which of the following options best describe the cover story?,"Small fragment molecules are vital for exploring receptor pharmacology and serve as building blocks for drug development. Advanced NMR techniques enable in situ identification of small-molecule ligands targeting receptors within native cell membranes, expanding drug discovery strategies.",B,MAC_Bench/ACS/Cover/ACS Chemical Biology/2017_7.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2017_7.png,vitg,2017_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_1.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_5.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_5.png,vith,2015_5.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,clip,2019_9.txt,train
Industrial & Engineering Chemistry Research,2024_40,Which of the following options best describe the cover story?,"In a whimsical journey through microchannel landscapes, our study delves into electroosmotic micromixing adventures. Navigating serpentine twists, we discover that strategically placed chemical patches induce counter-rotating vortices, enhancing mixing efficiency. Positive and negative ζ-potentials choreograph flow, offering a vibrant canvas for controlled microfluidic exploration.",D,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_20.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_20.png,ave_1,2022_20.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_49.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_49.png,ave_2,2023_49.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_20.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_20.png,clip,2023_20.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_40.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_40.png,groundtruth,2024_40.txt,test
Immunity,57_3,Which of the following options best describe the cover story?,"On the cover: The thymus involutes as we age, leading to reduced numbers of recent
thymic emigrant (RTE) naive T cells in circulation. Bohacova, Terekhova et al. examine human RTEs in a cohort of 158 individuals, providing insight into the impact
of age on RTE profile and functional potential and defining CD38 expression as a marker
of RTEs. RTEs—newly generated naive T cells—are depicted as a flock of migrating birds
emerging from a cloud (thymus). Having completed maturation, RTEs transition into
the bloodstream and eventually into the tissues, as evoked by migrating birds in search
of favorable environments. Image credit: Fishy Frog.",D,MAC_Bench/Cell/Cover/Immunity/38_5.png,MAC_Bench/Cell/Cover/Immunity/38_5.png,vitg,38_5.txt,MAC_Bench/Cell/Cover/Immunity/48_3.png,MAC_Bench/Cell/Cover/Immunity/48_3.png,clip,48_3.txt,MAC_Bench/Cell/Cover/Immunity/54_1.png,MAC_Bench/Cell/Cover/Immunity/54_1.png,vith,54_1.txt,MAC_Bench/Cell/Cover/Immunity/57_3.png,MAC_Bench/Cell/Cover/Immunity/57_3.png,groundtruth,57_3.txt,train
NATURE IMMUNOLOGY,25_12,Which of the following options best describe the cover story?,"Second-generation M1-polarized CAR macrophages
Induced pluripotent stem (iPS) cell-derived macrophages (iMACs) are being used to engineer CAR macrophages for immunotherapy. Zhang and colleagues design second-generation macrophage-specific CARs by integrating CD3ζ and TIR domains, resulting in M1-polarized CAR-iMACs with increased antitumor functions.
See Zhang et al.
Image credit: Jin Zhang, Zhejiang University. Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/23_3.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/23_3.png,clip,23_3.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/18_7.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/18_7.png,vitg,18_7.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_12.png,groundtruth,25_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_5.png,vith,22_5.txt,train
innovation,5_3,Which of the following options best describe the cover story?,"On the cover: Extremophiles are invaluable biological resources, pivotal for unraveling
the mysteries of life, revealing the origins and evolution of life on Earth, and exploring
extraterrestrial planets. Syntrichia caninervis, a desert moss, exemplifies life's remarkable adaptability to extreme environments.
It demonstrates extraordinary desiccation tolerance, capable of losing over 98% of
its cellular water content, and can endure −196°C ultra-low temperatures. Additionally,
it exhibits exceptional radiation resistance, withstanding doses of more than 5,000
Gy of gamma irradiation. This moss can survive and maintain vitality under simulated
Mars conditions. S. caninervis is one of the toughest plants on Earth, offering promising potential as a pioneer
species for future Mars colonization and terraforming efforts.",C,MAC_Bench/Cell/Cover/innovation/4_6.png,MAC_Bench/Cell/Cover/innovation/4_6.png,ave_3,4_6.txt,MAC_Bench/Cell/Cover/innovation/2_3.png,MAC_Bench/Cell/Cover/innovation/2_3.png,ave_2,2_3.txt,MAC_Bench/Cell/Cover/innovation/5_3.png,MAC_Bench/Cell/Cover/innovation/5_3.png,groundtruth,5_3.txt,MAC_Bench/Cell/Cover/innovation/3_6.png,MAC_Bench/Cell/Cover/innovation/3_6.png,clip,3_6.txt,train
NATURE BIOTECHNOLOGY,42_7,Which of the following options best describe the cover story?,"Modeling genetic perturbation outcomes
Predicting the outcome of genetic perturbations: Roohani et al. present GEARS, a computational method that integrates deep learning with a knowledge graph of gene–gene relationships to simulate the effects of genetic perturbations.
See Roohani et al.
Image: Yusuf Roohani, Jure Leskovec and SayoStudio. Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/30_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/30_4.png,vith,30_4.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_7.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_7.png,groundtruth,42_7.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/27_8.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/27_8.png,clip,27_8.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/35_5.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/35_5.png,vitg,35_5.txt,val
ACS Applied Polymer Materials,2024_6,Which of the following options best describe the cover story?,"Absorption and photorelease of specific organic substances from aqueous environments using tailored Q-silsesquioxane-azobenzene hybrid sponges. The image was generated through Adobe Photoshop (v 25.12) Generative AI, and the molecular structures were manually created using Avagadro (v 1.2.0).",D,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_6.png,groundtruth,2024_6.txt,train
Bioconjugate Chemistry,2024_2,Which of the following options best describe the cover story?,antibody has remained a challenge as the heat treatment required for [89Zr]Zr-DOTA coordination can potentially damage the antibody moiety. We circumvent this,A,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,vitg,2013_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2020_7.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2020_7.png,clip,2020_7.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2015_9.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2015_9.png,ave_0,2015_9.txt,train
Nature Reviews Rheumatology,20_2,Which of the following options best describe the cover story?,"Cover inspired by the Review on p671
Cover design: Steven Hall",A,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_2.png,groundtruth,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_9.png,vith,20_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,train
Nature Human Behaviour,8_7,Which of the following options best describe the cover story?,"Reconstructing the origins of Chinese dialects
The relative contribution of demographic versus cultural diffusion to the evolution of Han Chinese dialects has been unclear. By digitizing a large lexical dataset of Chinese dialects and comparing it to genetic profiles, Yang et al. reveal a hybrid model of language diffusion that consists of both population migrations and social learning across different regions of China.
See Yang et al. See also News & Views by Xu & Wang
Image: Menghan Zhang and Chengkun Yang from Fudan University, Kai Li and Valentine He from Kehuitang Art studio. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,ave_2,4_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_7.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_7.png,groundtruth,8_7.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/3_10.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/3_10.png,vitg,3_10.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_5.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_5.png,clip,6_5.txt,train
Nature Mental Health,2_7,Which of the following options best describe the cover story?,"Reflecting on LGBT+ mental health
Every June, Pride is celebrated. The theme for Pride 2024 in New York City — Reflect. Empower. Unite. — sends a special message to LGBT+ and allies that in order to foster solidarity and the pursuit of equality, it is necessary to reflect on the great strides made by previous generations. Although there are powerful and somber elements, Pride is also about uplift and joy and commitment to improving LGBT+ mental health and wellbeing. With a mirror ball reflecting the many colors of the inclusive LGBT+ flag, the cover for June symbolizes reflections of diversity that are united and ready to celebrate.
Read more in our Editorial about Pride and supporting LGBT+ mental health
Image: Ponomariova_Maria / iStock / Getty Images Plus. Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Nature Mental Health/1_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_10.png,ave_2,1_10.txt,MAC_Bench/Nature/Cover/Nature Mental Health/1_2.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_2.png,ave_3,1_2.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_7.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_7.png,groundtruth,2_7.txt,MAC_Bench/Nature/Cover/Nature Mental Health/1_7.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_7.png,clip,1_7.txt,test
Nature Catalysis,7_2,Which of the following options best describe the cover story?,"Radical strain-release
The authors report the use of azabicyclic scaffolds that release their ring strain thanks to an organic photosensitizer activated by visible light. The consequent radical ring opening enables the incorporation of organic fragments, allowing access to functionalized azetidines.
See Rodríguez et al.
Image: Benjamin Large. Cover design: Alex Whitworth.",B,MAC_Bench/Nature/Cover/Nature Catalysis/4_1.png,MAC_Bench/Nature/Cover/Nature Catalysis/4_1.png,vith,4_1.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_2.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_2.png,groundtruth,7_2.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_3.png,clip,2_3.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_1.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_1.png,vitg,2_1.txt,train
Nature Cell Biology,27_1,Which of the following options best describe the cover story?,"Chromosomal instability in cancer
Longitudinal analyses of non-small cell lung cancer samples identify the mechanisms through which loss of tumour suppressor FAT1 affects homologous recombination repair and chromosomal instability.
See Lu et al. , and RB by Wei-Ting Lu
Image: Jeroen Claus (Phospho Biomedical Animation). Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Cell Biology/18_3.png,MAC_Bench/Nature/Cover/Nature Cell Biology/18_3.png,vitg,18_3.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/18_10.png,MAC_Bench/Nature/Cover/Nature Cell Biology/18_10.png,vith,18_10.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/27_1.png,MAC_Bench/Nature/Cover/Nature Cell Biology/27_1.png,groundtruth,27_1.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/21_2.png,MAC_Bench/Nature/Cover/Nature Cell Biology/21_2.png,clip,21_2.txt,train
Cell Chemical Biology,31_5,Which of the following options best describe the cover story?,"On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.",A,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_5.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_5.png,groundtruth,31_5.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_15.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_15.png,vith,31_15.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_11.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_11.png,clip,31_11.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png,vitg,31_7.txt,train
Journal of Chemical Theory and Computation,2024_9,Which of the following options best describe the cover story?,The generalized cavity molecular dynamics scheme can efficiently simulate vibrational strong coupling for a layer of molecules confined in Fabry–Pérot optical cavities by sampling a collection of molecular ensembles in a grid.,D,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2020_7.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2020_7.png,clip,2020_7.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2016_3.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2016_3.png,vitg,2016_3.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_7.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_7.png,vith,2022_7.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_9.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_9.png,groundtruth,2024_9.txt,train
Trends in Cell Biology,34_1,Which of the following options best describe the cover story?,"Integrins mediate mechanical forces crucial for neuronal adaptation.
On pages 1029–1043 in this issue, Jaudon et al. discuss the dynamic role of integrins
in processes ranging from ion channel regulation to synaptic plasticity. Their review
emphasizes the importance of these forces in shaping neuronal interactions,
integrating classical cell biology perspectives with emerging mechanobiology
concepts. The authors highlight mechanosensitivity as critical in advancing our
understanding of brain function. Cover design by Giuseppe Di Scipio.",B,MAC_Bench/Cell/Cover/Trends in Cell Biology/24_3.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/24_3.png,clip,24_3.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_1.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_1.png,groundtruth,34_1.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_7.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_7.png,vith,23_7.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_4.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/23_4.png,vitg,23_4.txt,test
Nature Metabolism,6_1,Which of the following options best describe the cover story?,"Inuit genetic variants
4% of the Inuit population from snowy Greenland (pictured) are homozygous for a specific TBC1D4 loss-of-function variant, which leads to skeletal muscle insulin resistance but allows for a normal metabolic response to exercise.
See Kristensen, J. M., Kjøbsted, R. et al.
Image: Wirestock, Inc. / Alamy Stock Photo. Cover Design: Thomas Phillips.",C,MAC_Bench/Nature/Cover/Nature Metabolism/5_3.png,MAC_Bench/Nature/Cover/Nature Metabolism/5_3.png,vitg,5_3.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_9.png,clip,3_9.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_1.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_1.png,groundtruth,6_1.txt,MAC_Bench/Nature/Cover/Nature Metabolism/4_8.png,MAC_Bench/Nature/Cover/Nature Metabolism/4_8.png,vith,4_8.txt,train
Nature Cancer,5_9,Which of the following options best describe the cover story?,"Piecing together the puzzle of breast cancer
Multi-omics analyses of breast tumor samples from Chinese patients add more pieces to the puzzle of breast cancer.
See Jiang et al.
Image: Qin-Xin Wang. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Cancer/5_9.png,MAC_Bench/Nature/Cover/Nature Cancer/5_9.png,groundtruth,5_9.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_2.png,MAC_Bench/Nature/Cover/Nature Cancer/4_2.png,vith,4_2.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_11.png,MAC_Bench/Nature/Cover/Nature Cancer/5_11.png,vitg,5_11.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_7.png,MAC_Bench/Nature/Cover/Nature Cancer/4_7.png,clip,4_7.txt,train
Trends in Biochemical Sciences,49_12,Which of the following options best describe the cover story?,"UFMylation is the most recently identified ubiquitin-like modification. On
pages 52−67 in this issue, Zhou et al. review recent advances in the understanding of
the biochemical and structural bases of this post-translational protein modification
and
highlight the various intertwined cellular processes tightly controlled by UFMylation.
They
point out some of the outstanding research questions that will need to be addressed
to decipher the physiological importance of this modification and for evaluating the
potential of its pharmacological targeting. Cover image by Dr Elodie Lafont.",D,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,vitg,44_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_7.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_7.png,vith,45_7.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/43_12.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/43_12.png,clip,43_12.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_12.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_12.png,groundtruth,49_12.txt,test
Chemical & Biomedical ImagingOpen Access,2024_9,Which of the following options best describe the cover story?,ctivity-in,A,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_9.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,vith,2024_11.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_2.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_2.png,clip,2024_2.txt,train
NATURE GENETICS,56_3,Which of the following options best describe the cover story?,"Custom microfluidics for spatial transcriptomics
MAGIC-seq is a spatial transcriptomics method that combines multiple-grid microfluidic design and prefabricated DNA arrays.
See Zhu et al.
Image: Junjie Zhu, Institute of Zoology, Chinese Academy of Sciences. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/NATURE GENETICS/56_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_1.png,clip,56_1.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/53_5.png,MAC_Bench/Nature/Cover/NATURE GENETICS/53_5.png,vith,53_5.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/51_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/51_1.png,vitg,51_1.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_3.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_3.png,groundtruth,56_3.txt,train
NATURE REVIEWS CANCER,24_11,Which of the following options best describe the cover story?,"Jumping genes, inspired by the Review on p123.
Cover design: Lara Crow.",B,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,vith,17_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_11.png,groundtruth,24_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_1.png,clip,13_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_6.png,ave_1,13_6.txt,train
NATURE BIOTECHNOLOGY,42_3,Which of the following options best describe the cover story?,"Sparse, reliable biomarker discovery
Identifying a sparse, reliable set of biomarkers from large multi-omics datasets: Hédou et al. present a machine learning framework that selects the most reliable biomarkers from large multi-omics datasets. By injecting artificial noise (gray dots) into a dataset containing thousands of omics features (pink dots), Stabl calculates reliable predictive biomarkers (circled dots).
See Hédou et al.
Image: Clara Leibenguth. Cover design: Erin Dewalt",C,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/43_1.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/43_1.png,clip,43_1.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/30_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/30_4.png,vith,30_4.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_3.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_3.png,groundtruth,42_3.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_2.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_2.png,vitg,41_2.txt,train
Nature Reviews Materials,9_12,Which of the following options best describe the cover story?,"Broken symmetries at the nanoscale can greatly modify the emergent nanophotonic responses enabled by phonon polaritons, and lowering the degree of symmetry in natural and artificial materials gives rise to a wide spectrum of low-loss, directional, confined light–matter quasiparticles. The cover image shows an artist’s impression of extreme light confinement in low-symmetry crystals. See Galiffi E. et al.
Cover image: Sam Whitham.",A,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_12.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_12.png,groundtruth,9_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_4.png,clip,2_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,vitg,9_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_6.png,ave_0,4_6.txt,val
Journal of Agricultural and Food Chemistry,2025_1,Which of the following options best describe the cover story?,"Microorganisms secrete siderophores to acquire iron. Streptomyces, the well-known strains producing numerous metabolites, also produce a rich variety of siderophores with diverse structures that play important roles in many fields. This review provides an overview of the classification, structure, biosynthesis and applications of siderophores produced by Streptomyces,",C,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2023_20.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2023_20.png,clip,2023_20.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_14.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_14.png,vith,2021_14.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2024_35.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2024_35.png,vitg,2024_35.txt,train
Nano Letters,2025_4,Which of the following options best describe the cover story?,An evanescent near field (golden particles) beneath the apex of a metallic tip launches a surface plasmon polariton wave (golden surface wave) on an atomically thin graphene layer (hexagonal ball and stick model). View the article.,D,MAC_Bench/ACS/Cover/Nano Letters/2018_10.png,MAC_Bench/ACS/Cover/Nano Letters/2018_10.png,vitg,2018_10.txt,MAC_Bench/ACS/Cover/Nano Letters/2016_12.png,MAC_Bench/ACS/Cover/Nano Letters/2016_12.png,clip,2016_12.txt,MAC_Bench/ACS/Cover/Nano Letters/2024_17.png,MAC_Bench/ACS/Cover/Nano Letters/2024_17.png,vith,2024_17.txt,MAC_Bench/ACS/Cover/Nano Letters/2025_4.png,MAC_Bench/ACS/Cover/Nano Letters/2025_4.png,groundtruth,2025_4.txt,train
Nature Photonics,18_2,Which of the following options best describe the cover story?,"Ultra-intense Compton scattering
Artistic impression of a nonlinear Compton scattering experiment in which an electron bunch (blue) is accelerated by a laser wakefield to multi-gigaelectron volt energy and then collides with an ultra-intense petawatt laser pulse (red) and generates a strong gamma-ray beam (purple).
See Mirzaie et al.
Image: Ghazal Barati, Saeid Mirzaei and Mohammad Mirzaie (Center for Relativistic Laser Science). Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Photonics/16_7.png,MAC_Bench/Nature/Cover/Nature Photonics/16_7.png,vitg,16_7.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_2.png,MAC_Bench/Nature/Cover/Nature Photonics/18_2.png,groundtruth,18_2.txt,MAC_Bench/Nature/Cover/Nature Photonics/6_8.png,MAC_Bench/Nature/Cover/Nature Photonics/6_8.png,vith,6_8.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_10.png,MAC_Bench/Nature/Cover/Nature Photonics/18_10.png,clip,18_10.txt,train
ACS Engineering Au,2024_1,Which of the following options best describe the cover story?,"This work presents the sustainable green solvent engineering for the synthesis of REWO (RE = Ce, Sm, Gd) nanoparticles, which are modified disposable screenprinted carbon electrodes for the electrochemical detection of 4-nitrotoluene in real-time analysis of water samples.",D,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_1.png,clip,2021_1.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2023_5.png,ave_1,2023_5.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_2.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2021_2.png,ave_2,2021_2.txt,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_1.png,MAC_Bench/ACS/Cover/ACS Engineering Au/2024_1.png,groundtruth,2024_1.txt,train
Trends in Pharmacological Sciences,45_10,Which of the following options best describe the cover story?,"A key contributor to cancer-related mortality is metastasis — the process
where cancer cells disseminate from their original site to other body parts. During
the
metastatic cascade, cancer cells are challenged by hostile, highly dynamic and distinct
environments. Technological progress in ribosome profiling and other RNA sequencing-based
approaches has significantly deepened and expanded our understanding of the complex
ways in which cancer cells rapidly alter messenger RNA (mRNA) translation — a multistep
and highly coordinated process for protein synthesis — in response to environmental
stresses
(such as low oxygen, limited nutrient availability, immune response). In an article
of this issue,
Chen, Navickas, and Goodarzi discuss how changes in the translation machinery are
tailored
to specific sequence and structure information encoded in the mRNA, and interconnect
with
additional regulatory layers to drive breast cancer progression and metastasis. They
also
explore how understanding this complex process can be harnessed for developing novel
breast cancer treatment strategies, particularly those aimed at overcoming drug resistance
and
inhibiting the spread of cancer cells. Cover image is an adaptation of Figure 1 by
Chen et al.
designed via Adobe Illustrator and BioRender.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_2.png,vith,42_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/41_11.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/41_11.png,clip,41_11.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_10.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_10.png,groundtruth,45_10.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,vitg,34_8.txt,train
Macromolecules,2024_15,Which of the following options best describe the cover story?,"Di-block ring polymers in strongly segregated lamellar phase, where one di-block ring (light yellow-green) in original conformation is embedded inside the mesh of other di-block rings (dark yellow-green) in the primitive-path conformations.",B,MAC_Bench/ACS/Cover/Macromolecules/2021_18.png,MAC_Bench/ACS/Cover/Macromolecules/2021_18.png,vitg,2021_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_15.png,MAC_Bench/ACS/Cover/Macromolecules/2024_15.png,groundtruth,2024_15.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_18.png,MAC_Bench/ACS/Cover/Macromolecules/2010_18.png,vith,2010_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2015_4.png,MAC_Bench/ACS/Cover/Macromolecules/2015_4.png,clip,2015_4.txt,train
Nature Physics,20_6,Which of the following options best describe the cover story?,"Cell doublet pirouette
Cells can pair up and form a rotating doublet. Linjie Lu and collaborators have shown that these rotations are spontaneously caused by an uneven distribution of myosin within cell cortices. This polarized distribution breaks the mirror symmetry of the doublet. These results highlight how active mechanical forces drive collective cell motion.
See Lu et al.
Image: Linjie Lu, Tristan Guyomar, and Daniel Riveline (IGBMC-University of Strasbourg). Cover design: Emily Paul",B,MAC_Bench/Nature/Cover/Nature Physics/15_7.png,MAC_Bench/Nature/Cover/Nature Physics/15_7.png,ave_1,15_7.txt,MAC_Bench/Nature/Cover/Nature Physics/20_6.png,MAC_Bench/Nature/Cover/Nature Physics/20_6.png,groundtruth,20_6.txt,MAC_Bench/Nature/Cover/Nature Physics/19_2.png,MAC_Bench/Nature/Cover/Nature Physics/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/Nature Physics/20_5.png,MAC_Bench/Nature/Cover/Nature Physics/20_5.png,vitg,20_5.txt,train
Nature Plants,10_11,Which of the following options best describe the cover story?,"Tending to fire
Fire has been an ecological driving force on Earth as long as there have been plants to burn. But human activity has altered fire regimes in unprecedented ways, with profound global consequences for carbon storage, ecosystem services and biodiversity.
See Editorial
Image: imageBROKER.com GmbH & Co. KG/Alamy Stock Photo. Cover Design: Erin Dewalt.",B,MAC_Bench/Nature/Cover/Nature Plants/5_6.png,MAC_Bench/Nature/Cover/Nature Plants/5_6.png,clip,5_6.txt,MAC_Bench/Nature/Cover/Nature Plants/10_11.png,MAC_Bench/Nature/Cover/Nature Plants/10_11.png,groundtruth,10_11.txt,MAC_Bench/Nature/Cover/Nature Plants/5_1.png,MAC_Bench/Nature/Cover/Nature Plants/5_1.png,ave_2,5_1.txt,MAC_Bench/Nature/Cover/Nature Plants/5_11.png,MAC_Bench/Nature/Cover/Nature Plants/5_11.png,vitg,5_11.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_12,Which of the following options best describe the cover story?,"Pancreatic cancer, inspired by the Review on p7.
Cover design: Laura Marshall",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_6.png,vitg,18_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,clip,21_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_1.png,ave_2,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_12.png,groundtruth,21_12.txt,train
Nature Catalysis,7_7,Which of the following options best describe the cover story?,"Data science and catalysis
In their work, Manu Suvarna and Javier Pérez-Ramírez review the use of data-driven strategies in the three main areas of catalysis, that is, heterogeneous, homogeneous and biocatalysis, and provide a thorough statistical analysis of the current available methods and discuss how these are being employed.
See Suvarna et al.
Image: Constance Ko and Javier Pérez-Ramírez, ETH Zurich. Cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Catalysis/1_7.png,MAC_Bench/Nature/Cover/Nature Catalysis/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_7.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_7.png,groundtruth,7_7.txt,MAC_Bench/Nature/Cover/Nature Catalysis/3_11.png,MAC_Bench/Nature/Cover/Nature Catalysis/3_11.png,vith,3_11.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_10.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_10.png,clip,2_10.txt,train
Science Immunology,9_101,Which of the following options best describe the cover story?,"ONLINE COVER Delayed Deployment of Liver Macrophage Defenses. Newborns are particularly vulnerable to bloodstream bacterial infections that can lead to meningitis, but the mechanisms underlying this susceptibility are not fully understood. Araujo David et al. found that Kupffer cells (KCs)—specialized liver macrophages responsible for bacterial clearance from the bloodstream—relocate from the liver parenchyma to the sinusoids during the first week of life. The relocalization of KCs conferred mice with improved ability to clear bloodborne bacteria and prevent their dissemination to other organs. This month’s cover image, obtained using intravital microscopy, is a maximum-intensity Z-projection of an adult mouse liver after bloodstream bacterial infection. KCs expressing TIM4 (red) are positioned within CD31+ liver sinusoids (blue), where they can effectively capture fluorescent Escherichia coli (yellow) from the bloodstream. Credit: Bruna Araujo David/University of Calgary",B,MAC_Bench/Science/Cover/Science Immunology/8_90.png,MAC_Bench/Science/Cover/Science Immunology/8_90.png,clip,8_90.txt,MAC_Bench/Science/Cover/Science Immunology/9_101.png,MAC_Bench/Science/Cover/Science Immunology/9_101.png,groundtruth,9_101.txt,MAC_Bench/Science/Cover/Science Immunology/2_15.png,MAC_Bench/Science/Cover/Science Immunology/2_15.png,vith,2_15.txt,MAC_Bench/Science/Cover/Science Immunology/7_78.png,MAC_Bench/Science/Cover/Science Immunology/7_78.png,vitg,7_78.txt,train
ACS Applied Polymer Materials,2024_17,Which of the following options best describe the cover story?,"The image illustrates the impact of incorporating a polymer composed of partially hydrolyzed polyacrylamide and tannic acid, symbolized by tangled coils, into water, resulting in a viscous liquid. The polymer molecule serves as the background, while the image has a green hue to reflect the color of tannic acid.",C,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_17.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_1.png,vith,2023_1.txt,train
Trends in Plant Science,29_5,Which of the following options best describe the cover story?,"Living organisms rely on chemical and mechanical stimuli to adapt to
their environment. Among these stimuli, vibrations transmitted through substrates
are particularly important in influencing animal behavior and triggering physiological
responses in plants. This has led to the development of the field of biotremology,
which is
experiencing significant growth in both fundamental research and practical applications
such as pest control. As connections between biotremology and chemical ecology
become apparent, there is a growing need for a shared standardized vocabulary in the
overlapping areas to facilitate mutual understanding among different audiences. Valerio
Mazzoni and colleagues propose an updated set of terms in biotremology rooted in
chemical ecology, using the suffix “-done” derived from the classic Greek word “δονέω”
(pronounced “doneo”), meaning “to shake”. Image credit: Valerio Mazzoni.",B,MAC_Bench/Cell/Cover/Trends in Plant Science/19_12.png,MAC_Bench/Cell/Cover/Trends in Plant Science/19_12.png,clip,19_12.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_5.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_5.png,groundtruth,29_5.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/27_6.png,MAC_Bench/Cell/Cover/Trends in Plant Science/27_6.png,vitg,27_6.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/19_7.png,MAC_Bench/Cell/Cover/Trends in Plant Science/19_7.png,vith,19_7.txt,train
Cell Reports Methods,4_12,Which of the following options best describe the cover story?,"On the cover: In this issue, Sakamoto et al. develop a semi-automated platform for synthesis of fluorogenic probes that can detect
enzyme activities in the blood at a single-molecule level. The activity-based screening
identifies candidate biomarkers for pancreatic tumors at early stages. In the cover
image, the bloodstream and the enzymes are depicted by the river and the fireflies,
respectively. The background shows the images of synthesized probes and the enzyme
activity assay. Cover art: Dr. Ryo Tachibana, Graduate School of Pharmaceutical Sciences,
The University of Tokyo.",C,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,vith,2_11.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_2.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_2.png,vitg,3_2.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_12.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_12.png,groundtruth,4_12.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_1.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_1.png,clip,2_1.txt,train
Journal of Proteome Research,2025_1,Which of the following options best describe the cover story?,Data-independent acquisition (DIA) proteomics analysis conducted on children’s saliva identified characteristic proteins in caries-susceptible children prior to caries development. Keratin 3 (KRT3) and mucin 21 (MUC21) were established and further validated as a protein panel for predicting early childhood caries.,A,MAC_Bench/ACS/Cover/Journal of Proteome Research/2025_1.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2015_4.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2015_4.png,vith,2015_4.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_3.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_5.png,MAC_Bench/ACS/Cover/Journal of Proteome Research/2016_5.png,vitg,2016_5.txt,train
Accounts of Materials Research,2024_11,Which of the following options best describe the cover story?,Photon upconversion converts multiple low-energy photons to a high-energy one. The cover image depicts the sensitization of photon upconversion by semiconductor quantum dots and the emission of upconverted photons through the annihilation of two emitter triplets. This strategy can be potentially applied in solar energy conversion and beyond.,C,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_7.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_7.png,ave_1,2021_7.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_9.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_9.png,vith,2021_9.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_11.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_3.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_3.png,clip,2024_3.txt,val
NATURE MEDICINE,30_6,Which of the following options best describe the cover story?,"Focus on Precision Health
This special Focus issue is all about precision health, the tailoring of preventive and treatment approaches to individuals based on their unique characteristics, across different geographical and clinical contexts.
The cover shows a heart created from fruits and vegetables representing the work from Bermingham et al. showing that personalized dietary programs can lead to significant improvements in cardiometabolic and gut health.
See Bermingham et al.
Image: ZOE. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/NATURE MEDICINE/9_4.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/9_4.png,vith,9_4.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/10_8.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/10_8.png,vitg,10_8.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/28_3.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/28_3.png,clip,28_3.txt,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_6.png,MAC_Bench/Nature/Cover/NATURE MEDICINE/30_6.png,groundtruth,30_6.txt,train
Cell Host&Microbe,32_1,Which of the following options best describe the cover story?,"On the cover: Scanning electron microscopy (SEM) of neutrophils (blue) infected with
Mycobacterium tuberculosis (pink) and releasing neutrophil extracellular traps (NETs, yellow). In this issue
of Cell Host & Microbe, Sur Chowdhury and colleagues demonstrate that extracellular M. tuberculosis are directly associated with the NETs that are studded with antimicrobial effectors,
but the M. tuberculosis are not killed and instead thrive in the presence of the NETs neutrophils.",B,MAC_Bench/Cell/Cover/Cell Host&Microbe/16_1.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/16_1.png,vitg,16_1.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_1.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_1.png,groundtruth,32_1.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/10_6.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/10_6.png,vith,10_6.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/6_6.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/6_6.png,clip,6_6.txt,train
Nature Ecology & Evolution,8_12,Which of the following options best describe the cover story?,"African raptor declines
Many African raptors have suffered severe, widespread declines since the 1970s, and at the same time have become significantly more dependent on protected areas. Their loss has the potential to trigger extensive cascading effects, particularly in the case of large, apex predators such as this martial eagle (Polemaetus bellicosus), seen here having just killed a black-backed jackal (Canis mesomelas).
See Shaw et al.
Image: Munir Virani, Mohamed Bin Zayed, Raptor Conservation Fund. Cover Design: Allen Beattie.",B,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_1.png,clip,8_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_12.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_12.png,groundtruth,8_12.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_10.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_7.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_7.png,vitg,8_7.txt,train
Cell Reports,43_10,Which of the following options best describe the cover story?,"On the cover: In this 3D reconstruction of zebrafish epicardial fat, the coronary
vascular system (pink) is intertwined with adipocytes (engulfed in flames) that have
thermogenic potential in response to cold exposure. In this issue, Morocho-Jaramillo et al. show that beige like epicardial adipocytes in zebrafish are key metabolic regulators,
similar to healthy human epicardial fat. Concept and artwork: Paul A. Morocho Jaramillo.",D,MAC_Bench/Cell/Cover/Cell Reports/23_6.png,MAC_Bench/Cell/Cover/Cell Reports/23_6.png,vith,23_6.txt,MAC_Bench/Cell/Cover/Cell Reports/13_9.png,MAC_Bench/Cell/Cover/Cell Reports/13_9.png,vitg,13_9.txt,MAC_Bench/Cell/Cover/Cell Reports/37_2.png,MAC_Bench/Cell/Cover/Cell Reports/37_2.png,clip,37_2.txt,MAC_Bench/Cell/Cover/Cell Reports/43_10.png,MAC_Bench/Cell/Cover/Cell Reports/43_10.png,groundtruth,43_10.txt,train
ACS Nanoscience Au,2025_1,Which of the following options best describe the cover story?,"This work presents an oil-in-water nanoemulsion incorporating essential oils or hexane extract from Boesenbergia rotunda and betamethasone dipropionate (BD). The inclusion of B. rotunda hexane extract, which is rich in pinostrobin, significantly enhances the bioactivities of the BD nanoemulsion for managing atopic dermatitis. These improvements include antioxidant, antibacterial, and anti-inflammatory properties, along with enhanced in vitro skin barrier repair, all while maintaining nontoxicity to skin cells. This cover art features an AI-generated element, further refined with design software.",A,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_3.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_3.png,vith,2023_3.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_4.png,clip,2022_4.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_2.png,vitg,2024_2.txt,train
Nature Synthesis,3_10,Which of the following options best describe the cover story?,"Robot makes oxygen from Martian meteorites
A robotic artificial intelligence (AI)-chemist is developed to synthesize oxygen-producing electrocatalysts from Martian meteorites, combining both automated experiments and theoretical simulations to identify the optimal synthetic formula for the catalyst.
See Zhu et al.
Image: Jun Jiang and Luyuan Zhao. Cover design: Amie Fernandez",D,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_2.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_2.png,vith,1_2.txt,MAC_Bench/Nature/Cover/Nature Synthesis/4_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/4_1.png,clip,4_1.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_10.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_10.png,groundtruth,3_10.txt,train
Cell Genomics,4_9,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Hansen, Fong, et al. identify differences in the activity of human and rhesus macaque gene regulatory
elements that result from changes to the sequence vs. changes in the cell environment.
Inspired by Andy Warhol's screen prints in which repeated images with variations highlight
contrasts not visible in the original image, the cover illustrates the study design
in which human and macaque sequence activities are contrasted between human and rhesus
macaque backgrounds. The image was created by Tony Capra. The Marilyn Monroe photo
is from the public domain, and the rhesus macaque photo is by Charles J. Sharp released
under a Creative Commons license (CC BY-SA 4.0).",A,MAC_Bench/Cell/Cover/Cell Genomics/4_9.png,MAC_Bench/Cell/Cover/Cell Genomics/4_9.png,groundtruth,4_9.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_2.png,MAC_Bench/Cell/Cover/Cell Genomics/3_2.png,vith,3_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_6.png,MAC_Bench/Cell/Cover/Cell Genomics/3_6.png,clip,3_6.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_7.png,MAC_Bench/Cell/Cover/Cell Genomics/2_7.png,vitg,2_7.txt,test
Crystal Growth & Design,2024_24,Which of the following options best describe the cover story?,"liquid interfacial tension γeff, which suppresses the formation of crystal nuclei and leads to an increase in the nucleation energy barriers.",B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_5.png,clip,2019_5.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_24.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_24.png,groundtruth,2024_24.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_15.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_15.png,vitg,2024_15.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,vith,2017_5.txt,train
Bioconjugate Chemistry,2024_12,Which of the following options best describe the cover story?,"Efficient synthesis of novel glucuronic acid glycodendrimers with different scaffolds and different levels of multivalency as potent Dengue virus inhibitors. Using SPR and molecular modeling studies, the antiviral activity of these glycodendrimers was evaluated against Dengue virus. This antiviral evaluation indicated that glycodendrimers with flexible scaffolds and a high level of multivalency present strong binding affinity. This family of glycodendrimers can be considered as novel Dengue virus lead compounds.",D,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,vitg,2010_3.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_5.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2023_9.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2023_9.png,vith,2023_9.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_12.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_12.png,groundtruth,2024_12.txt,train
ACS Measurement Science Au,2022_1,Which of the following options best describe the cover story?,artwork by Mariana Avila and Diana Mancera entitled “Reach for the Stars – inspiring Latin American women in STEM”.,B,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png,ave_1,2022_2.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,groundtruth,2022_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_3.png,ave_3,2022_3.txt,train
Cancer Cell,42_5,Which of the following options best describe the cover story?,"On the cover: Sun et al. characterize the mechanistic significance and diagnostic potential of plasma and
fecal metabolites in colorectal cancer (CRC). The cover artwork depicts the journey
of sailboats, symbolizing CRC progression. The dolphins (representing inhibitory metabolites
like allocholic acid) swim alongside a boat veering away from a storm, while sharks
(representing promoting metabolites like oleic acid) follow a boat heading into the
storm. A buoy at the diverging paths signifies early tumor diagnosis based on metabolite
analysis. Image credit: Jun Yu.",A,MAC_Bench/Cell/Cover/Cancer Cell/42_5.png,MAC_Bench/Cell/Cover/Cancer Cell/42_5.png,groundtruth,42_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/33_1.png,MAC_Bench/Cell/Cover/Cancer Cell/33_1.png,vitg,33_1.txt,MAC_Bench/Cell/Cover/Cancer Cell/40_3.png,MAC_Bench/Cell/Cover/Cancer Cell/40_3.png,clip,40_3.txt,MAC_Bench/Cell/Cover/Cancer Cell/35_3.png,MAC_Bench/Cell/Cover/Cancer Cell/35_3.png,vith,35_3.txt,val
Trends in Biotechnology,42_11,Which of the following options best describe the cover story?,"The image shows three planets in space, one of which is surrounded
by a representation of synthetic DNA to allude to the unifying way to share information
between asynchronous societies. In pages 156−167 of this issue, Gervasio and
colleagues discuss how DNA could be a universal solution to storing data—as long as
DNA is ubiquitous to known life. Cover image from Aaron Aznar.",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_11.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_11.png,groundtruth,42_11.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/39_2.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/39_2.png,vitg,39_2.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/40_9.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/40_9.png,vith,40_9.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/29_5.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/29_5.png,clip,29_5.txt,train
Nature Reviews Endocrinology,20_2,Which of the following options best describe the cover story?,"Endocrine and metabolic effects of heat stress, inspired by the Perspective on p673.
Edward Byrne",B,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,vitg,19_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_2.png,groundtruth,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_9.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_9.png,clip,18_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_7.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_7.png,vith,17_7.txt,train
Nature Reviews Psychology,3_1,Which of the following options best describe the cover story?,"In this Review, Schmid et al. describe the costs and benefits of vaccine mandates and alternative approaches that could promote vaccine uptake.
Cover design: David Johnston",D,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_2.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_2.png,ave_2,3_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_2.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_2.png,ave_3,2_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_4.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_4.png,clip,3_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_1.png,groundtruth,3_1.txt,train
ACS Applied Bio Materials,2024_1,Which of the following options best describe the cover story?,"The ACS AMI Family “2024 Early Career Forum” highlights groundbreaking research and innovative ideas from the emerging authors in the scientific community on a broad range of topics. This edition of the Forum showcases 135 exceptional contributions from early-career scientists worldwide, published across ACS Applied Materials & Interfaces, ACS Applied Bio Materials, ACS Applied Electronic Materials, ACS Applied Engineering Materials, ACS Applied Energy Materials, ACS Applied Nano Materials, ACS Applied Optical Materials, and ACS Applied Polymer Materials.",A,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_4.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_11.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_11.png,ave_2,2024_11.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_10.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_10.png,ave_3,2022_10.txt,train
Environment & Health,2024_11,Which of the following options best describe the cover story?,"This image shows that two routes (IVI and INI) of silica nanoparticle exposure resulted in different outcomes of brain damage. The Baidu Wenxin Yige platform was used to improve the cover image, drawn using SAI software.",D,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,ave_2,2023_1.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_2.png,MAC_Bench/ACS/Cover/Environment & Health/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,ave_3,2024_9.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_11.png,MAC_Bench/ACS/Cover/Environment & Health/2024_11.png,groundtruth,2024_11.txt,test
NATURE ENERGY,9_12,Which of the following options best describe the cover story?,"Unequal electricity regulation protection in Australia
Those living further from urban areas are at higher risk for procedural neglect of energy needs. White et al. find that remote communities and those with a majority Indigenous population are more likely to be underserved by electricity retail legal protections in Australia.
See White et al.
Image: Simonology / 500px / Getty Images. Cover design: Thomas Phillips.",D,MAC_Bench/Nature/Cover/NATURE ENERGY/5_10.png,MAC_Bench/Nature/Cover/NATURE ENERGY/5_10.png,vith,5_10.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/7_8.png,MAC_Bench/Nature/Cover/NATURE ENERGY/7_8.png,vitg,7_8.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/6_8.png,MAC_Bench/Nature/Cover/NATURE ENERGY/6_8.png,clip,6_8.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_12.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_12.png,groundtruth,9_12.txt,train
ACS Photonics,2024_5,Which of the following options best describe the cover story?,Jeong-Hwan Lee et al. introduce a novel machine-learning algorithm for optimizing OLED structures. This algorithm efficiently and automatically evaluates optimized OLED structures for achieving a target emission color using two CIEscore and Zscore indicators with a remarkably small error margin of less than 0.5% for RGB-emitting OLEDs.,C,MAC_Bench/ACS/Cover/ACS Photonics/2017_5.png,MAC_Bench/ACS/Cover/ACS Photonics/2017_5.png,clip,2017_5.txt,MAC_Bench/ACS/Cover/ACS Photonics/2020_10.png,MAC_Bench/ACS/Cover/ACS Photonics/2020_10.png,ave_1,2020_10.txt,MAC_Bench/ACS/Cover/ACS Photonics/2024_5.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/ACS Photonics/2020_2.png,MAC_Bench/ACS/Cover/ACS Photonics/2020_2.png,vitg,2020_2.txt,train
ACS Applied Bio Materials,2025_1,Which of the following options best describe the cover story?,"Chronic wounds are challenging due to infections and antibiotic resistance. This study develops hydrogels with gallium-based nanoalloys, combining bismuth and silver ions. These multi-metallic hydrogels exhibit antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa while being non-toxic and enhancing wound healing, providing an alternative to current antimicrobial treatments. The i",C,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2018_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2018_1.png,clip,2018_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_12.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_12.png,vith,2019_12.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_2.png,ave_1,2025_2.txt,train
Cell Stem Cell,31_7,Which of the following options best describe the cover story?,"On the cover: In this issue, Martins-Costa et al. report that mutations in ARID1B, part of the mSWI/SNF complex, lead to agenesis of the corpus callosum, causing the
interhemispheric white matter tract to be absent in humans. Through a human neural
organoid model, they reveal that ARID1B haploinsufficiency affects the maturation of callosal projection neurons and their
ability to form long-range axons, resulting in structural underconnectivity phenotypes.
The cover shows an abstract illustration of the two brain hemispheres resembling the
intricate architecture of a modern city skyline. The highlight in the center is a
suspension bridge, reminiscent of the corpus callosum, inviting reflections on the
complexity of neural communication and connections in our central nervous system.
Image courtesy of the authors and Philipp Dexheimer (http://www.philippdexheimer.com/).",A,MAC_Bench/Cell/Cover/Cell Stem Cell/31_7.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_7.png,groundtruth,31_7.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,vitg,6_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,clip,31_3.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/5_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/5_1.png,ave_1,5_1.txt,train
Nature Cell Biology,26_1,Which of the following options best describe the cover story?,"Cell division in embryos
Blocking cell division in zebrafish embryos does not affect differentiation of embryonic tissues during gastrulation and segmentation but does decelerate differentiation of particular cells.
See Kukreja et al.
Image: Bill Z Jia, Kalki Kukreja and Sean G Megason, Harvard Medical School. Cover design: Lauren Heslop",D,MAC_Bench/Nature/Cover/Nature Cell Biology/8_7.png,MAC_Bench/Nature/Cover/Nature Cell Biology/8_7.png,clip,8_7.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/15_11.png,MAC_Bench/Nature/Cover/Nature Cell Biology/15_11.png,vith,15_11.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/9_3.png,MAC_Bench/Nature/Cover/Nature Cell Biology/9_3.png,vitg,9_3.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_1.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_1.png,groundtruth,26_1.txt,test
Nature Reviews Earth & Environment,5_12,Which of the following options best describe the cover story?,"Sonification uses non-speech audio to convey complex data patterns in both space and time, overcoming visual and language barriers to science communication. This Commentoutlines how data sonification is primed to aid interpretations of multi-dimensional Earth and environmental data streams.
Image credit: Tom Gernon. Cover design: Carl Conway.",C,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_12.png,clip,2_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_12.png,vitg,1_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_12.png,groundtruth,5_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_7.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_7.png,ave_2,3_7.txt,train
Accounts of Chemical Research,2024_9,Which of the following options best describe the cover story?,"This cover illustration highlights the sophisticated design and application of stretchable physiological microelectrode arrays (MEAs), emphasizing their function as adaptable and biocompatible interfaces for neuron–motor pathways. These state-of-the-art MEAs are crafted to accommodate the dynamic movements of biological tissues, guaranteeing stable and accurate electrophysiological measurements. This breakthrough technology is poised to enhance numerous biomedical applications, such as neural prosthetics and brain–machine interfaces. The exceptional biocompatibility and mechanical resilience of these MEAs facilitate enduring real-time neural signal monitoring, propelling our comprehension and capacity to regulate neural functions for therapeutic interventions.",C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_4.png,ave_3,2025_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_17.png,clip,2022_17.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_8.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_8.png,ave_2,2022_8.txt,train
Nature Cancer,5_8,Which of the following options best describe the cover story?,"Efferocytosis links macrophage reprogramming and liver metastasis
Hepatic colonization by pancreatic cancer cells is accompanied by low-grade tissue injury and efferocytosis, which promotes macrophage reprogramming and liver metastasis.
See Astuti et al.
Image: Yuliana Astuti, University of Liverpool, UK. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Cancer/1_6.png,MAC_Bench/Nature/Cover/Nature Cancer/1_6.png,vith,1_6.txt,MAC_Bench/Nature/Cover/Nature Cancer/1_4.png,MAC_Bench/Nature/Cover/Nature Cancer/1_4.png,vitg,1_4.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_8.png,MAC_Bench/Nature/Cover/Nature Cancer/5_8.png,groundtruth,5_8.txt,MAC_Bench/Nature/Cover/Nature Cancer/3_8.png,MAC_Bench/Nature/Cover/Nature Cancer/3_8.png,clip,3_8.txt,test
Inorganic Chemistry,2025_3,Which of the following options best describe the cover story?,"The cover image illustrates that the incorporation of Fe ions (orange) into CuO-based materials (blue) holds great promise for enhancing oxygen-evolution reaction (OER) performance. Especially, this study using different methods and strategies reveals that Fe ions anchored to the CuO surface significantly enhance OER performance. These findings offer valuable insights into the role of Fe in CuO structures for advancing electrocatalysis efficiency.",D,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_4.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_4.png,clip,2025_4.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_22.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_22.png,vith,2023_22.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2018_17.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2018_17.png,ave_1,2018_17.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_3.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_3.png,groundtruth,2025_3.txt,train
Nature Structural & Molecular Biology,31_2,Which of the following options best describe the cover story?,"Long noncoding RNAs use structural mimicry
Two studies by Skeparnias et al. and Skeparnias and Zhang uncover a Père David’s deer-like design for the long noncoding RNAs MALAT1 and NEAT1, respectively, which partially mimic tRNA structure to recruit specific tRNA-processing enzymes during their maturation.
See Skeparnias et al. and Skeparnias and Zhang
Image credit: Jeremy Inglis / Alamy Stock Photo. Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_9.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_9.png,vitg,31_9.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_2.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_2.png,groundtruth,31_2.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_10.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_10.png,ave_2,25_10.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/27_4.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/27_4.png,clip,27_4.txt,test
ACS Applied Energy Materials,2025_2,Which of the following options best describe the cover story?,"The cover art illustrates a porous carbon electrode integrated with a conductive, interconnected substrate. The heat dissipation within the porous structure represents efficient thermal management and electron transport, essential for high-performance energy-storage systems. The structured carbon layer facilitates ion diffusion and charge storage, emphasizing advancements in electrode design for battery technologies.",A,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2023_13.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2023_13.png,vitg,2023_13.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2019_8.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2019_8.png,ave_1,2019_8.txt,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Energy Materials/2024_9.png,clip,2024_9.txt,train
Nature Reviews Clinical Oncology,21_7,Which of the following options best describe the cover story?,"Going deep with NIR-II light, inspired by the Review on p449.
Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_7.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_7.png,groundtruth,21_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_3.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/18_3.png,ave_3,18_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_4.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_4.png,vith,19_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_9.png,clip,20_9.txt,train
NATURE REVIEWS CANCER,25_1,Which of the following options best describe the cover story?,"Transitioning through mountain terrain, inspired by the Review on p7.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,ave_1,25_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_1.png,groundtruth,25_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,clip,23_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_3.png,ave_3,13_3.txt,train
ACS Applied Polymer Materials,2024_12,Which of the following options best describe the cover story?,"The adsorbent materials act as guardians, adeptly capturing and containing the released iodine. The porous structure serves as a trap, preventing iodine from spreading further and mitigating its impact on the environment and human health. This symbiotic relationship between industry and technology showcases a promising avenue for sustainable and responsible management of hazardous substances.",A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_1.png,clip,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,vith,2025_2.txt,val
ACS Polymers Au,2024_4,Which of the following options best describe the cover story?,"The synthesis of amino-acid-derived polyanions is shown. These polymers, depending on the chemical identity of the amino acid, reveal chirality and tailored hydrophilicity, enabling them to accumulate in cell membranes in a particularly slow fashion.",C,MAC_Bench/ACS/Cover/ACS Polymers Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2022_4.png,vitg,2022_4.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,clip,2023_6.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,vith,2023_4.txt,train
Nature Mental Health,2_8,Which of the following options best describe the cover story?,"ADHD in adulthood
The cover of the May issue uses a braid of several colorful threads woven together to symbolize some of the current thinking about attention-deficit/hyperactivity disorder (ADHD) in adulthood. Adult ADHD is not well understood and, consequently, can be overdiagnosed, underdiagnosed and misdiagnosed. But recent work has attempted to identify the ways in which ADHD in adulthood may be both different from and similar to ADHD diagnosed in childhood by bringing many strands of research together. The braid also symbolizes the need for increasing the awareness of, reducing the stigma of and providing better treatment and multifactorial support for people with ADHD in adulthood.
Read more in our Editorial about the neurobiological basis of ADHD in adults and parental support and self-management in people with ADHD transitioning to adulthood.
Image and cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/1_7.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_8.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_8.png,groundtruth,2_8.txt,train
Trends in Cell Biology,34_5,Which of the following options best describe the cover story?,"Fluorescence-activated cell sorting (FACS) is a powerful technology
for sorting cells based on fluorescent characteristics. Yet, it is limited to whole-cell
analysis and cannot distinguish individual organelles or subcellular structures. Novel
cell sorting platforms with imaging capabilities have ushered in a new era of cell
sorting,
enabling sorting based on images with subcellular resolution. On pages 657–670 in
this issue, Kuhn et al. review image-activated cell sorting technologies accessible
to the broader research community, discussing their strengths and weaknesses and
presenting use cases in basic and clinical research.
Cover design by illustratoren.de/TobiasWuestefeld.",D,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_10.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_10.png,clip,34_10.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_3.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/26_3.png,vith,26_3.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/32_9.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/32_9.png,ave_1,32_9.txt,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_5.png,MAC_Bench/Cell/Cover/Trends in Cell Biology/34_5.png,groundtruth,34_5.txt,train
Science,387_6735,Which of the following options best describe the cover story?,"COVER A mother elephant seal rests with her pup after returning from a 7-month, 10,000-kilometer foraging trip to the northeast Pacific Ocean, where she made ~75,000 attempts to feed on twilight zone fish. Seals’ foraging success across decades reveals variation in fish abundance, which drives large fluctuations in the survival and reproductive success of their offspring. See page 764.
Photo: Bruce Lyon, under National Marine Fisheries Service (NMFS) research permit no. 23188",A,MAC_Bench/Science/Cover/Science/387_6735.png,MAC_Bench/Science/Cover/Science/387_6735.png,groundtruth,387_6735.txt,MAC_Bench/Science/Cover/Science/382_6674.png,MAC_Bench/Science/Cover/Science/382_6674.png,ave_2,382_6674.txt,MAC_Bench/Science/Cover/Science/384_6697.png,MAC_Bench/Science/Cover/Science/384_6697.png,clip,384_6697.txt,MAC_Bench/Science/Cover/Science/353_6300.png,MAC_Bench/Science/Cover/Science/353_6300.png,vitg,353_6300.txt,test
ACS Earth and Space Chemistry,2024_4,Which of the following options best describe the cover story?,"Nitrate salts are found in both the hyper-arid Atacama Desert in Chile and the Martian regolith. Fernanders et al. measure nitrate salt deliquescence and apply the data to sites in the Atacama, one pictured here, as well as to Gale Crater, Mars. Photo by Diana Boy. Mars image courtesy NASA/JPL-Caltech/MSSS.",D,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_1.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_1.png,ave_2,2022_1.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2025_2.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,ave_3,2024_10.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_4.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_4.png,groundtruth,2024_4.txt,train
NATURE REVIEWS CANCER,24_1,Which of the following options best describe the cover story?,"Terraforming a new organ site, inspired by the Review on p829.
Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_11.png,clip,23_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_1.png,groundtruth,24_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_12.png,vitg,24_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/18_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/18_12.png,vith,18_12.txt,train
Science Immunology,9_100,Which of the following options best describe the cover story?,"ONLINE COVER Sex-Biased Gene Regulation in T Cells. In females, X chromosome inactivation (XCI) represses gene expression from one X chromosome to balance gene dosage between the sexes. This process is controlled by the long noncoding RNA Xist, which coats the inactive X chromosome and promotes epigenetic gene silencing. Forsyth et al. studied XCI in mouse and human T cells, a process that is much more dynamic in T cells than in most other somatic cells. NF-κB signaling downstream of the T cell receptor was required for the localization of Xist to the inactive X chromosome and the maintenance of XCI after T cell activation. This month’s cover illustration depicts Xist (orange) localizing to the inactive X chromosome on the right. Credit: Noelle Burgess/Science Immunology",B,MAC_Bench/Science/Cover/Science Immunology/9_92.png,MAC_Bench/Science/Cover/Science Immunology/9_92.png,vith,9_92.txt,MAC_Bench/Science/Cover/Science Immunology/9_100.png,MAC_Bench/Science/Cover/Science Immunology/9_100.png,groundtruth,9_100.txt,MAC_Bench/Science/Cover/Science Immunology/2_17.png,MAC_Bench/Science/Cover/Science Immunology/2_17.png,vitg,2_17.txt,MAC_Bench/Science/Cover/Science Immunology/3_28.png,MAC_Bench/Science/Cover/Science Immunology/3_28.png,clip,3_28.txt,test
Journal of the American Chemical Society,2024_22,Which of the following options best describe the cover story?,"A heterophase intermetallic as an efficient electrocatalyst is developed for the first time. The enhanced electron transfer between two components and the formed phase boundaries in Ru2Ge3/RuGe lead to enhanced water adsorption, fast water dissociation kinetics,",D,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_42.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_42.png,vitg,2016_42.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_16.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2017_16.png,vith,2017_16.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_16.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_16.png,clip,2018_16.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_22.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_22.png,groundtruth,2024_22.txt,test
Nature Sustainability,7_10,Which of the following options best describe the cover story?,"Sustainable space
We are rapidly expanding our reach into Earth’s orbital space and beyond. The adverse impacts of this development occur right here on Earth’s surface and in our atmosphere, in our near orbital space and all the way to our ability to see into the stars. As we show in this month’s Focus, it is now urgent to extend our notions of protecting a sustainable future on Earth to ensure a sustainable future in space.
See Editorial
Credit: NASA/ESA/STScI. Cover Design: Alex Whitworth.",A,MAC_Bench/Nature/Cover/Nature Sustainability/7_10.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_10.png,groundtruth,7_10.txt,MAC_Bench/Nature/Cover/Nature Sustainability/6_7.png,MAC_Bench/Nature/Cover/Nature Sustainability/6_7.png,ave_3,6_7.txt,MAC_Bench/Nature/Cover/Nature Sustainability/2_12.png,MAC_Bench/Nature/Cover/Nature Sustainability/2_12.png,clip,2_12.txt,MAC_Bench/Nature/Cover/Nature Sustainability/2_3.png,MAC_Bench/Nature/Cover/Nature Sustainability/2_3.png,vith,2_3.txt,train
Acta Pharmacologica Sinica,45_8,Which of the following options best describe the cover story?,"Cover Credit: Following MIR, MCMECs release GMCSF to recruit monocyte infiltration, which in turn releases CCL2 to induce CCR2+ immune cell infiltration. GMCSF transits CCR2+ macrophages to M1 phenotype, mediating and amplifying inflammation that exacerbates MIR injury, while CCL2 transits CCR2+ macrophages to M2 phenotype, mediating fibrotic remodeling after MIR.",B,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,vitg,45_9.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_8.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_8.png,groundtruth,45_8.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_11.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/43_11.png,vith,43_11.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_4.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_4.png,clip,41_4.txt,val
ACS Organic & Inorganic Au,2023_4,Which of the following options best describe the cover story?,Phosphonated pyridines play an important role in various areas of chemistry. Those structures can now be conveniently synthesized in a simple and metal-free procedure. Mechanistic investigations indicate that the products are formed as illustrated in thermodynamically-controlled reactions.,A,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_4.png,groundtruth,2023_4.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,vith,2023_5.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,ave_1,2023_6.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,clip,2024_4.txt,train
Trends in Chemistry,6_13,Which of the following options best describe the cover story?,"The upcoming micro-optics revolution has been set to transform how we
create optical devices for various industries. To date, scientists mostly focus on
organic/
inorganic photoresins for 3D printing, allowing us to print structures whose scale
lies
beyond our eyesight. In their Forum article, Winczewski and co-authors highlight the
need to develop cutting-edge photoresins for 3D printing that transform into functional
glass/ceramics upon heat exposure. Innovation at the forefront is crucial to paving
the way for crafting unique multi-material optical components with spatially dissimilar
compositions. Cover Image Credit: Ella Maruschenko - Ella Maru Studio",B,MAC_Bench/Cell/Cover/Trends in Chemistry/4_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_5.png,ave_3,4_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_13.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_13.png,groundtruth,6_13.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/4_2.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_2.png,vith,4_2.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,clip,5_9.txt,train
Nature Food,5_11,Which of the following options best describe the cover story?,"Food loss and waste
Food that is lost or wasted along supply chains contributes to climate change, depletes natural resources, threatens economic stability and compromises progress towards food security. A global database identifies regional hotspots in low- and middle-income regions where food loss and waste (FLW) in agricultural production and post-harvest handling and storage contribute towards nutrient losses and environmental footprints. Between 2004 and 2014, FLW increased by a quarter, especially in regions confronted with food insecurity. Overconsumption in high-income regions drives FLW elsewhere via international trade. Policies and strategies aimed at reducing FLW must consider the complex interplay between food production, trade, consumption patterns, and their social and environmental impacts.
See Gatto et al.
Image: Paul Smith / Alamy Stock Photo. Cover Design: Tulsi Voralia.",A,MAC_Bench/Nature/Cover/Nature Food/5_11.png,MAC_Bench/Nature/Cover/Nature Food/5_11.png,groundtruth,5_11.txt,MAC_Bench/Nature/Cover/Nature Food/4_4.png,MAC_Bench/Nature/Cover/Nature Food/4_4.png,clip,4_4.txt,MAC_Bench/Nature/Cover/Nature Food/1_2.png,MAC_Bench/Nature/Cover/Nature Food/1_2.png,vitg,1_2.txt,MAC_Bench/Nature/Cover/Nature Food/3_7.png,MAC_Bench/Nature/Cover/Nature Food/3_7.png,ave_1,3_7.txt,train
NATURE REVIEWS GENETICS,25_9,Which of the following options best describe the cover story?,"Inspired by the Review on p237.
Cover design: Patrick Morgan",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_8.png,clip,25_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_9.png,groundtruth,25_9.txt,test
Cell Reports Physical Science,5_1,Which of the following options best describe the cover story?,"On the cover: This artistic representation showcases a 3D-printed Ti-6Al-4V screw
designed for spinal procedures. Karavasili et al. show that its fenestrated, microstructured geometry enables precise antibiotic release
via an injectable hydrogel composite, promoting osteoblast activity and inhibiting
bacterial growth. A fusion of engineering and biomedicine, this innovation potentially
offers a safer, patient-specific alternative to traditional bone cement. Image by
ScienceBrush Design.",A,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_1.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_1.png,groundtruth,5_1.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_8.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_8.png,clip,5_8.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_6.png,vitg,2_6.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_6.png,vith,3_6.txt,train
Med,5_4,Which of the following options best describe the cover story?,"On the cover: Artificial intelligence (AI) has made significant strides in biomedical
research, showcasing its transformative potential in driving innovation within drug
development. In this issue of Med, Zhang et al. review the significant advancements in AI-assisted drug development, focusing on
small molecules, RNA, and antibodies. The review highlights the challenge in obtaining
approval for AI-conceived drugs and proposes leveraging large language models and
diffusion models as solutions. The cover image captures two AI robots analyzing AI-generated
drugs in a clinical environment, symbolizing AI's transformative impact on drug discovery,
development, and clinical trials.",D,MAC_Bench/Cell/Cover/Med/4_12.png,MAC_Bench/Cell/Cover/Med/4_12.png,vitg,4_12.txt,MAC_Bench/Cell/Cover/Med/4_9.png,MAC_Bench/Cell/Cover/Med/4_9.png,clip,4_9.txt,MAC_Bench/Cell/Cover/Med/3_1.png,MAC_Bench/Cell/Cover/Med/3_1.png,vith,3_1.txt,MAC_Bench/Cell/Cover/Med/5_4.png,MAC_Bench/Cell/Cover/Med/5_4.png,groundtruth,5_4.txt,test
Immunity,58_2,Which of the following options best describe the cover story?,"On the cover: Inpp5d, a risk gene for Alzheimer’s disease, encodes the lipid phosphatase SHIP1. Matera, Compagnion, et al. demonstrate that Inpp5d is expressed in microglia during early postnatal brain development, where it limits
synaptic pruning in a complement-dependent manner. Perturbation of Inpp5d during brain development has long-lasting effects on cognitive function. The cover
image depicts microglial cells (magenta) interacting with neurons (cyan) in the mouse
CA1 hippocampal region during early development, specifically at postnatal day 15.
The plasticity and dynamism of microglia, which constantly scan the brain environment,
are highlighted by oil painting effect. Image acquisition and editing by Alessandro
Matera.",C,MAC_Bench/Cell/Cover/Immunity/57_4.png,MAC_Bench/Cell/Cover/Immunity/57_4.png,clip,57_4.txt,MAC_Bench/Cell/Cover/Immunity/42_5.png,MAC_Bench/Cell/Cover/Immunity/42_5.png,vith,42_5.txt,MAC_Bench/Cell/Cover/Immunity/58_2.png,MAC_Bench/Cell/Cover/Immunity/58_2.png,groundtruth,58_2.txt,MAC_Bench/Cell/Cover/Immunity/36_6.png,MAC_Bench/Cell/Cover/Immunity/36_6.png,vitg,36_6.txt,train
ACS Applied Polymer Materials,2024_4,Which of the following options best describe the cover story?,This cover illustration shows superior thermal conducting properties of newly developed liquid crystal (LC) materials derived from improved molecular orientation by polymerization. LC epoxy resins exhibit high thermal conductivity based on mesogen networks oriented by intermolecular interactions with excellent potential as electronic materials.,A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_11.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_11.png,vith,2023_11.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,vitg,2020_12.txt,test
NATURE ENERGY,9_10,Which of the following options best describe the cover story?,"Hydrogen goes underground
Hydrogen could be introduced into subsurface environments for seasonal energy storage, but technical feasibility is unclear as large-scale demonstrations are scarce. Hellerschmied, Schritter et al. perform field tests in a depleted underground hydrocarbon reservoir in Austria (similar to that shown here), demonstrating that hydrogen can be stored and microbially converted to methane.
See Hellerschmied et al. and News and Views by Strous
Image: RAG Austria AG / USS 2030. Cover design: Thomas Phillips",C,MAC_Bench/Nature/Cover/NATURE ENERGY/1_4.png,MAC_Bench/Nature/Cover/NATURE ENERGY/1_4.png,vith,1_4.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/3_3.png,MAC_Bench/Nature/Cover/NATURE ENERGY/3_3.png,clip,3_3.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/9_10.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_10.png,groundtruth,9_10.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/8_10.png,MAC_Bench/Nature/Cover/NATURE ENERGY/8_10.png,vitg,8_10.txt,train
NATURE METHODS,21_7,Which of the following options best describe the cover story?,"Mapping white matter in chimpanzee
Transverse view of a whole-brain tract-density reconstruction of white matter pathways in the chimpanzee brain. Color indicates tissue orientation and brightness encodes density of reconstructed fiber streamlines.
See Eichner et al.
Image: Cornelius Eichner, Max Planck Institute for Human Cognitive and Brain Sciences. Cover design: Thomas Phillips",B,MAC_Bench/Nature/Cover/NATURE METHODS/21_6.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_6.png,ave_3,21_6.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_7.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_7.png,groundtruth,21_7.txt,MAC_Bench/Nature/Cover/NATURE METHODS/19_8.png,MAC_Bench/Nature/Cover/NATURE METHODS/19_8.png,clip,19_8.txt,MAC_Bench/Nature/Cover/NATURE METHODS/13_3.png,MAC_Bench/Nature/Cover/NATURE METHODS/13_3.png,ave_2,13_3.txt,val
Analytical Chemistry,2025_6,Which of the following options best describe the cover story?,"The inclusive droplet digital ELISA (iddELISA) expands the boundaries of digital immunoassays by incorporating all types of bead encapsulations into the analysis, enhancing assay efficiency, and simplifying operations. This innovative approach holds great promise for the early detection of low-abundance biomarkers.",D,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_2.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_2.png,clip,2019_2.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,vith,2022_33.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_22.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_22.png,vitg,2020_22.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_6.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_6.png,groundtruth,2025_6.txt,train
Nature Reviews Rheumatology,20_1,Which of the following options best describe the cover story?,"Inspired by the Review on p747.
Cover design: Steven Hall",C,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,vitg,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_2.png,clip,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_1.png,groundtruth,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/13_3.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/13_3.png,vith,13_3.txt,val
Cell Stem Cell,31_11,Which of the following options best describe the cover story?,"On the cover: Yan, Li, Gao, et al. develop a 3D bioprinting technology that assembles human stem cell-derived neural
progenitors into neural tissues with functional connectivity. The cover illustrates
human brain tissue with functional networks (denoted in line nets) generated by 3D
bioprinting (indicated by protrusion of cells/bioink from the nozzles). Cover art
by Xin Zou.",D,MAC_Bench/Cell/Cover/Cell Stem Cell/7_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/7_4.png,ave_1,7_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,vith,31_3.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/30_11.png,MAC_Bench/Cell/Cover/Cell Stem Cell/30_11.png,clip,30_11.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_11.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_11.png,groundtruth,31_11.txt,train
Nature Reviews Materials,9_2,Which of the following options best describe the cover story?,"Space exploration offers opportunities for scientific discovery, but the materials we use are critical to its success. Materials that can withstand harsh environments, innovations in materials manufacturing and energy-efficient technologies are essential for achieving viable and sustainable space missions, allowing us to explore new worlds. See the Editorial.
Cover design: David Johnston.",A,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_2.png,groundtruth,9_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_1.png,vitg,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_11.png,clip,7_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_4.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_4.png,vith,4_4.txt,train
Environmental Science & Technology,2025_1,Which of the following options best describe the cover story?,NO3RR,D,MAC_Bench/ACS/Cover/Environmental Science & Technology/2009_3.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2009_3.png,ave_1,2009_3.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2020_22.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2020_22.png,vitg,2020_22.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/1975_3.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/1975_3.png,clip,1975_3.txt,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_1.png,MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_1.png,groundtruth,2025_1.txt,test
Cancer Cell,42_11,Which of the following options best describe the cover story?,"On the cover: Zhou et al. report the results of a phase 3 trial that demonstrates the efficacy and safety of
serplulimab plus chemotherapy as first-line treatment for patients with advanced squamous
non-small-cell lung cancer (sqNSCLC). The cover shows a collage of pathology slices
and lively colors that represent the complexity of the disease but also symbolize
how the results of this ASTRUM-004 study have invigorated research and innovation
in sqNSCLC.",A,MAC_Bench/Cell/Cover/Cancer Cell/42_11.png,MAC_Bench/Cell/Cover/Cancer Cell/42_11.png,groundtruth,42_11.txt,MAC_Bench/Cell/Cover/Cancer Cell/38_6.png,MAC_Bench/Cell/Cover/Cancer Cell/38_6.png,clip,38_6.txt,MAC_Bench/Cell/Cover/Cancer Cell/27_1.png,MAC_Bench/Cell/Cover/Cancer Cell/27_1.png,vith,27_1.txt,MAC_Bench/Cell/Cover/Cancer Cell/39_4.png,MAC_Bench/Cell/Cover/Cancer Cell/39_4.png,vitg,39_4.txt,val
Accounts of Materials Research,2024_2,Which of the following options best describe the cover story?,"High-quality semiconductor fibers were developed by a thermal drawing technique with selected pairs of semiconductor materials and synthetic materials, including silicon and germanium, glassy semiconductors, and two-dimensional semiconductors. The semiconductor fibers may find multiple applications in the field of wearable electronics, such as on-cloth sensors and wearable energy harvesting and storage devices.",D,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_8.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_12.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_12.png,vitg,2023_12.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_11.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_11.png,ave_2,2022_11.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_2.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_2.png,groundtruth,2024_2.txt,train
ACS ES&T Water,2024_7,Which of the following options best describe the cover story?,This work shows the marriage of single atoms with nanoparticles for enhanced peroxymonosulfate (PMS) activation. The built-in electric field assisted Co SAs for efficient PMS activation via a nonradical pathway.,C,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_8.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_8.png,ave_3,2021_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_5.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_5.png,clip,2024_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_7.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_3.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_3.png,vitg,2021_3.txt,val
ACS Sensors,2024_11,Which of the following options best describe the cover story?,"Visualization of a flow sensor mounted on a guidewire for blood flow measurement in coronary arteries [sensor on wire (SoW)], fabricated through laser sintering of metal nanoparticles: The sensor derives the coronary flow waveform corresponding to the heartbeat.",B,MAC_Bench/ACS/Cover/ACS Sensors/2020_8.png,MAC_Bench/ACS/Cover/ACS Sensors/2020_8.png,vith,2020_8.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_11.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Sensors/2018_9.png,MAC_Bench/ACS/Cover/ACS Sensors/2018_9.png,clip,2018_9.txt,MAC_Bench/ACS/Cover/ACS Sensors/2020_5.png,MAC_Bench/ACS/Cover/ACS Sensors/2020_5.png,vitg,2020_5.txt,train
Cell Host&Microbe,32_4,Which of the following options best describe the cover story?,"On the cover: Probiotics are potential treatments for ulcerative colitis, but their
efficacy is frequently compromised by gastrointestinal conditions that limit adhesion
and activity. In this issue of Cell Host & Microbe, Guo et al. engineered Lactobacillus casei to contain selenium dots embedded in the pericellular film (represented by the cloak
decorated with red dots). Upon oral administration, engineered Lactobacillus casei efficiently enhanced gastric acid resistance and intestinal mucoadhesion, which potentiated
the synergistic restoration of gut microbiota and redox homeostasis (represented by
the engineered Lactobacillus casei waving the wand to cast spells).",D,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/31_4.png,vith,31_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/28_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/28_4.png,clip,28_4.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/30_3.png,vitg,30_3.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_4.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/32_4.png,groundtruth,32_4.txt,train
iScience,28_3,Which of the following options best describe the cover story?,"On the cover: The illustration represents the core concept of collaborative trajectory
following in a connected and automated airspace environment driven by 5G technology.
Leveraging the low-latency global 5G network, aircraft acquire the capability for
high-speed information exchange and real-time interaction necessary for global connectivity.
By integrating intelligent aircraft following and interactions within autonomous connected
airspace, the system achieves a dynamic and orderly stability in trajectory following,
demonstrating adaptive resilience to environmental disturbances. This highlights the
creation of a highly connected, collaborated, and stable future air traffic operation
system. This vision aligns with the framework proposed by Huang et al., offering an intelligent connected aircraft-following model. Image source: Xiao Huang.",D,MAC_Bench/Cell/Cover/iScience/18_1.png,MAC_Bench/Cell/Cover/iScience/18_1.png,ave_3,18_1.txt,MAC_Bench/Cell/Cover/iScience/28_2.png,MAC_Bench/Cell/Cover/iScience/28_2.png,clip,28_2.txt,MAC_Bench/Cell/Cover/iScience/25_5.png,MAC_Bench/Cell/Cover/iScience/25_5.png,ave_2,25_5.txt,MAC_Bench/Cell/Cover/iScience/28_3.png,MAC_Bench/Cell/Cover/iScience/28_3.png,groundtruth,28_3.txt,train
NATURE IMMUNOLOGY,25_9,Which of the following options best describe the cover story?,"Predicting and evaluating drugs for combination therapy
Guo and colleagues present a method known as CM-Drug for the identification of combination drugs that can boost the efficacy of immune checkpoint blockade therapy. They validate this method using melanoma and lung cancer models in mice and explore one hit from their screen in further depth, the thyrotropin-releasing hormone (TRH) analogue taltirelin.
See Guo et al.
Image: Yun Xia. Cover design: Amie Fernandez",A,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_9.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_9.png,groundtruth,25_9.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,clip,11_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/17_4.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/17_4.png,vith,17_4.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/14_10.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/14_10.png,vitg,14_10.txt,val
Nature Neuroscience,27_12,Which of the following options best describe the cover story?,"AgRP neurons encode circadian mealtimes
To maximize fitness, most animals adopt an optimal foraging strategy to procure the highest energy at the lowest cost. For example, nighttime is likely to be preferred by nocturnal animals owing to its relative safety from predators and the ease of food availability. In an environment with such periodic food availability, AgRP neurons are entrained by past successful feeding experiences and use this circadian information to promote foraging at similar time windows on subsequent days to maximize the chance of feeding.
See Sayar-Atasoy et al.
Image: Muhammed Ikbal Alp, InSpira. Cover Design: Marina Corral Spence",D,MAC_Bench/Nature/Cover/Nature Neuroscience/26_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/26_11.png,ave_1,26_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/24_6.png,MAC_Bench/Nature/Cover/Nature Neuroscience/24_6.png,vitg,24_6.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/12_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/12_2.png,clip,12_2.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_12.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_12.png,groundtruth,27_12.txt,train
Nature Cell Biology,26_11,Which of the following options best describe the cover story?,"Human embryonic arrest
Single-cell multi-omics of arrested human embryos reveal that cytoskeletal defects cause embryonic arrest characterized by zygotic genome activation.
See Li et al.
Image: Lin Li and Teng Wang, Southern Medical University. Cover Design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Cell Biology/26_11.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_11.png,groundtruth,26_11.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/10_6.png,MAC_Bench/Nature/Cover/Nature Cell Biology/10_6.png,vitg,10_6.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/19_9.png,MAC_Bench/Nature/Cover/Nature Cell Biology/19_9.png,vith,19_9.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/20_5.png,MAC_Bench/Nature/Cover/Nature Cell Biology/20_5.png,clip,20_5.txt,train
Current Biology,34_8,Which of the following options best describe the cover story?,"On the cover: A shingleback lizard (Tiliqua rugosa) in defensive display shows off its characteristic bright blue tongue. In this issue,
Brennan et al. explore how novel phenotypes—like the shingleback—arise through discontinuous evolutionary
processes. In Australia, heterogeneous morphological evolution has led to an array
of forms, from giant blue-tongue lizards to armored dwarf skinks. Photograph © Jules
Farquhar; used with permission.",B,MAC_Bench/Cell/Cover/Current Biology/32_2.png,MAC_Bench/Cell/Cover/Current Biology/32_2.png,clip,32_2.txt,MAC_Bench/Cell/Cover/Current Biology/34_8.png,MAC_Bench/Cell/Cover/Current Biology/34_8.png,groundtruth,34_8.txt,MAC_Bench/Cell/Cover/Current Biology/33_18.png,MAC_Bench/Cell/Cover/Current Biology/33_18.png,ave_2,33_18.txt,MAC_Bench/Cell/Cover/Current Biology/34_4.png,MAC_Bench/Cell/Cover/Current Biology/34_4.png,vith,34_4.txt,train
Trends in Biotechnology,42_1,Which of the following options best describe the cover story?,"CRISPR-driven genetic circuits have offered promising solutions to
burgeoning challenges in RNA sensing. In pages 1601–1614 of this issue, Jiang and
colleagues discuss cutting-edge developments in CRISPR-powered RNA sensors
in vivo, in addition to providing new insights on the future development of these
programmable RNA sensors. Cover image from Baojun Wang.",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_1.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_1.png,groundtruth,42_1.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/31_6.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/31_6.png,vith,31_6.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/34_7.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/34_7.png,clip,34_7.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_12.png,vitg,38_12.txt,train
Science Immunology,9_93,Which of the following options best describe the cover story?,"ONLINE COVER A Neuroimmune Circuit Drives Chronic UTI Pain. Recurrent urinary tract infections (rUTIs) can cause urinary frequency and chronic pelvic pain, even after the original bacterial infection has resolved. Hayes et al. detected the sprouting of nociceptive (pain-sensing) sensory neurons in bladder biopsies from rUTI patients. When they recapitulated this phenomenon in a murine rUTI model, they found that bladder nerve sprouting was triggered in mice by the release of nerve growth factor (NGF) from bladder-resident mast cells and recruited monocytes during the infection. Inhibition of chronic mast cell activation, however, could curb NGF release and nerve sprouting to limit pelvic pain. This month’s cover illustration depicts mast cells (purple) releasing NGF (blue vesicles) to promote the sprouting of nerves (yellow and orange). Credit: N. Burgess/Science Immunology",D,MAC_Bench/Science/Cover/Science Immunology/8_88.png,MAC_Bench/Science/Cover/Science Immunology/8_88.png,clip,8_88.txt,MAC_Bench/Science/Cover/Science Immunology/2_17.png,MAC_Bench/Science/Cover/Science Immunology/2_17.png,vith,2_17.txt,MAC_Bench/Science/Cover/Science Immunology/5_48.png,MAC_Bench/Science/Cover/Science Immunology/5_48.png,ave_1,5_48.txt,MAC_Bench/Science/Cover/Science Immunology/9_93.png,MAC_Bench/Science/Cover/Science Immunology/9_93.png,groundtruth,9_93.txt,train
Molecular Plant,18_2,Which of the following options best describe the cover story?,"On the cover: Crop research and breeding are crucial for ensuring global food security. To provide
adequate food for a growing global population, multiple challenges must be tackled
by innovative fundamental research and new technologies/strategies for breeding climate-resilient
and high-quality crops with optimal yields. In this issue, a series of authoritative
Perspectives on “Crop2035” are published to provide holistic and strategic visions
and solutions on next decadal research and breeding of some staple crops. The cover
image illustrates the landscape of the globe and major cultivated crops that will
be studied and engineered with advanced technologies in the coming years.",B,MAC_Bench/Cell/Cover/Molecular Plant/16_5.png,MAC_Bench/Cell/Cover/Molecular Plant/16_5.png,clip,16_5.txt,MAC_Bench/Cell/Cover/Molecular Plant/18_2.png,MAC_Bench/Cell/Cover/Molecular Plant/18_2.png,groundtruth,18_2.txt,MAC_Bench/Cell/Cover/Molecular Plant/10_1.png,MAC_Bench/Cell/Cover/Molecular Plant/10_1.png,ave_1,10_1.txt,MAC_Bench/Cell/Cover/Molecular Plant/10_6.png,MAC_Bench/Cell/Cover/Molecular Plant/10_6.png,vith,10_6.txt,train
NATURE IMMUNOLOGY,25_11,Which of the following options best describe the cover story?,"Immune dysregulation in long COVID
Yin et al. use Olink proteomics and single‐cell RNA sequencing (scRNA-seq) analyses to show a dysregulated crosstalk between the cellular and humoral immune responses in individuals with long COVID 8 months after infection with SARS-CoV-2.
See Kailin Yin et al.
Image credit: Amie Fernandez. Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,clip,11_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_11.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_11.png,groundtruth,25_11.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/20_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/20_5.png,vith,20_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/15_8.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/15_8.png,vitg,15_8.txt,train
ACS Organic & Inorganic Au,2023_5,Which of the following options best describe the cover story?,"PET is a pernicious pollutant, that takes hundreds of years to break down, and accumulates in the environment. Most current strategies to recycle PET are both costly and ineffective, making enzymatic strategies to biodegrade PET particularly attractive. In particular, PET-degrading enzymes are conformationally flexible, and evolutionary conformational selection provides a strategy to enhance their activity. This, in turn, shines light on new paths to rescue our plastic-polluted oceans.",D,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,ave_3,2023_1.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,groundtruth,2023_5.txt,train
The Journal of Physical Chemistry A,2025_5,Which of the following options best describe the cover story?,". The cover art depicts a selection of images that represent important scientific results achieved by Saykally and his group. Top left: image showing second harmonic generation probing of solutes at an air-water interface (reprinted with permission from J. Phys. Chem. Lett. 2018, 9, (16), 4753–4757, DOI:",A,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_5.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2022_24.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2022_24.png,vitg,2022_24.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_50.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_50.png,vith,2024_50.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2019_20.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2019_20.png,clip,2019_20.txt,train
Molecular Plant,17_13,Which of the following options best describe the cover story?,"On the cover: The cover image illustrates a leaf of the fern Ceratopteris richardii infected by the pathogenic fungus Sclerotinia scleroriorum. An angiosperm pathogen can infect a non-angiosperm plant, suggesting at least partial
conservation of molecular regulation of plant-microbe interactions. Overlay of real
colour image and 488nm-excited fluorescent image after dye with GFP-conjugated Wheat
Germ Agglutin, known to bind chitin. Image by Baptiste CASTEL with the assistance
of NightCafé (https://creator.nightcafe.studio).",D,MAC_Bench/Cell/Cover/Molecular Plant/14_3.png,MAC_Bench/Cell/Cover/Molecular Plant/14_3.png,clip,14_3.txt,MAC_Bench/Cell/Cover/Molecular Plant/16_1.png,MAC_Bench/Cell/Cover/Molecular Plant/16_1.png,vitg,16_1.txt,MAC_Bench/Cell/Cover/Molecular Plant/9_6.png,MAC_Bench/Cell/Cover/Molecular Plant/9_6.png,vith,9_6.txt,MAC_Bench/Cell/Cover/Molecular Plant/17_13.png,MAC_Bench/Cell/Cover/Molecular Plant/17_13.png,groundtruth,17_13.txt,test
Macromolecules,2024_13,Which of the following options best describe the cover story?,"Schematic representation of a four-dimensional scanning transmission electron microscopy experiment, where the electron beam (in green) scans across a block copolymer sample (in black/white) recording diffraction patterns (below) that reveal the orientation (rainbow colors) of the semicrystalline crystalline structure (shown top left as the atomic structure).",D,MAC_Bench/ACS/Cover/Macromolecules/2024_5.png,MAC_Bench/ACS/Cover/Macromolecules/2024_5.png,vith,2024_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2011_23.png,MAC_Bench/ACS/Cover/Macromolecules/2011_23.png,clip,2011_23.txt,MAC_Bench/ACS/Cover/Macromolecules/2023_17.png,MAC_Bench/ACS/Cover/Macromolecules/2023_17.png,vitg,2023_17.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_13.png,MAC_Bench/ACS/Cover/Macromolecules/2024_13.png,groundtruth,2024_13.txt,test
ACS Materials Letters,2024_2,Which of the following options best describe the cover story?,easy control over film crystallization,A,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_2.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_12.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_12.png,vith,2023_12.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_1.png,clip,2022_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_3.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_3.png,vitg,2019_3.txt,train
Cell Reports Methods,4_6,Which of the following options best describe the cover story?,"On the cover: In this issue, Bartelt et al. present an immunofluorescence-based protocol that effectively isolates a pure fraction
of Purkinje cell nuclei, enabling further in-depth studies on these rare neuronal
cells. The cover illustration features an artistic interpretation of Purkinje cells
(nuclei in green) and is courtesy of Dorota Moniuszko.",B,MAC_Bench/Cell/Cover/Cell Reports Methods/2_6.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_6.png,clip,2_6.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_6.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_6.png,groundtruth,4_6.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/1_6.png,MAC_Bench/Cell/Cover/Cell Reports Methods/1_6.png,vitg,1_6.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_12.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_12.png,vith,4_12.txt,train
ACS Omega,2025_1,Which of the following options best describe the cover story?,"Flavin-dependent tryptophan halogenases like AbeH show great potential as synthetic tools for regioselective green aryl halide production, despite suboptimal catalytic efficiency. Crystallography and ITC have determined that negative coupling between flavin and substrate binding limits turnover by preventing tryptophan from binding to AbeH as long as flavin remains bound.",A,MAC_Bench/ACS/Cover/ACS Omega/2025_1.png,MAC_Bench/ACS/Cover/ACS Omega/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Omega/2021_17.png,MAC_Bench/ACS/Cover/ACS Omega/2021_17.png,clip,2021_17.txt,MAC_Bench/ACS/Cover/ACS Omega/2024_29.png,MAC_Bench/ACS/Cover/ACS Omega/2024_29.png,vitg,2024_29.txt,MAC_Bench/ACS/Cover/ACS Omega/2019_18.png,MAC_Bench/ACS/Cover/ACS Omega/2019_18.png,vith,2019_18.txt,val
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_10,Which of the following options best describe the cover story?,"Monitoring coeliac disease, inspired by the Evidence-Based Guidelines on p198.
Cover design: Laura Marshall.",B,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_11.png,vitg,20_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_10.png,groundtruth,21_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_11.png,clip,21_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_2.png,vith,21_2.txt,train
Trends in Endocrinology & Metabolism,35_2,Which of the following options best describe the cover story?,"Restoring functional beta cell mass is an essential step in curing
diabetes. While regenerating beta cells directly within the pancreas is an attractive
solution, its clinical translation has proven to be challenging. This month, Bourgeois
and colleagues discuss how new insights into beta cell regeneration can be used to
change diabetes therapy, shifting from “caring for” to “curing” this disorder. The
cover,
symbolizing renewal and transformation, merges a phoenix rising from its ashes with
a pancreatic islet. Cover credit: Len Degroote / Althar.be",B,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_4.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_4.png,vith,25_4.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_2.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_2.png,groundtruth,35_2.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/25_6.png,clip,25_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_12.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_12.png,vitg,27_12.txt,val
Accounts of Chemical Research,2024_13,Which of the following options best describe the cover story?,"Falling from the heavens, C60 fullerene and its derivatives have continued to bring surprises to humans in a variety of fields. This Account discussed the multifaceted properties and applications of fullerene–metal complexes and clusters, ranging from fundamental structural chemistry to the forefront of single atom catalysis and to astrophysics and astrochemistry.",C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_17.png,vitg,2021_17.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2016_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2016_4.png,vith,2016_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_13.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_13.png,groundtruth,2024_13.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,clip,2024_17.txt,train
Chem & Bio Engineering,2024_2,Which of the following options best describe the cover story?,Engineering a new generation of multimodular chimera lytic polysaccharide monooxygenases to bind and degrade plastics.,D,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_5.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_5.png,ave_2,2024_5.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_8.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_8.png,ave_3,2024_8.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,groundtruth,2024_2.txt,val
Nature Nanotechnology,19_12,Which of the following options best describe the cover story?,"Counting protein subunits in native membrane nanodiscs
The cover image depicts the capturing of cellular membranes together with their native environment in the form of nanodiscs using amphipathic copolymers. Imaged by a single-molecule technique, the nanodiscs reveal the oligomeric distribution of membrane proteins.
See Walker et al.
Credit line: Hannah Wang, Yale University; Cover design: Valentina Monaco.",D,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_10.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_10.png,vitg,19_10.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_4.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_4.png,vith,18_4.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_12.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_12.png,groundtruth,19_12.txt,train
Nature Biomedical Engineering,8_7,Which of the following options best describe the cover story?,"Microscopic localization of fluorescence during glioma-resection surgery
The cover illustrates that paired stimulated Raman histology and two-photon excitation fluorescence microscopy improves the detection of fluorescent protoporphyrin IX during glioma-resection surgery.
See Nasir-Moin et al.
Image: Dieter Henrik Heiland. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/3_1.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/3_1.png,ave_3,3_1.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_7.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_7.png,groundtruth,8_7.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_6.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_6.png,clip,4_6.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_10.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_10.png,vitg,4_10.txt,train
Caner Cell,42_3,Which of the following options best describe the cover story?,"On the cover: Fitzsimons et al. present a comprehensive pan-cancer single-cell RNA-seq atlas of intratumoral B cells,
revealing key associations with responses to immune checkpoint inhibitor therapy and
placing these findings in a spatial context. The cover artwork depicts the identification
of B cells within the tumor microenvironment, illustrating the high-resolution phenotyping
of distinct B cell subsets.",D,MAC_Bench/Cell/Cover/Caner Cell/32_2.png,MAC_Bench/Cell/Cover/Caner Cell/32_2.png,clip,32_2.txt,MAC_Bench/Cell/Cover/Caner Cell/42_8.png,MAC_Bench/Cell/Cover/Caner Cell/42_8.png,vith,42_8.txt,MAC_Bench/Cell/Cover/Caner Cell/23_5.png,MAC_Bench/Cell/Cover/Caner Cell/23_5.png,vitg,23_5.txt,MAC_Bench/Cell/Cover/Caner Cell/42_3.png,MAC_Bench/Cell/Cover/Caner Cell/42_3.png,groundtruth,42_3.txt,train
ACS Materials Letters,2024_6,Which of the following options best describe the cover story?,"Ultra-pure organic crystals do not display long-lived emission and, hence, can be perceived as essentially dark 3D frameworks. The review highlights that phosphorescence within these dark frameworks can be only achieved if tiny amounts of impurities are added. The impurities act as exciton traps and enable long-lived emission.",B,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_10.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_10.png,vith,2024_10.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_6.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_10.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_10.png,clip,2022_10.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_5.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_5.png,vitg,2023_5.txt,train
The Journal of Physical Chemistry C,2025_2,Which of the following options best describe the cover story?,"The cover art depicts an isolated hydroxyl-bridged tricopper triangular complex being lifted from the kagomé lattice of herbertsmithite, illustrating how our new compound, CaCu(OH)3Cl, represents a chemically equivalent zero-dimensional analogue of this well studied quantum spin liquid candidate. View the article.",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2022_32.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2022_32.png,clip,2022_32.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_2.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2024_30.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2024_30.png,vith,2024_30.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2024_39.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2024_39.png,vitg,2024_39.txt,train
JACS Au,2024_12,Which of the following options best describe the cover story?,"CO3 layer undergoes direct carbonate hydrogenation with limited decomposition, pointing out a new path for gas-solid CO2 upgradation.",C,MAC_Bench/ACS/Cover/JACS Au/2021_3.png,MAC_Bench/ACS/Cover/JACS Au/2021_3.png,clip,2021_3.txt,MAC_Bench/ACS/Cover/JACS Au/2021_12.png,MAC_Bench/ACS/Cover/JACS Au/2021_12.png,vitg,2021_12.txt,MAC_Bench/ACS/Cover/JACS Au/2024_12.png,MAC_Bench/ACS/Cover/JACS Au/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/JACS Au/2022_7.png,MAC_Bench/ACS/Cover/JACS Au/2022_7.png,vith,2022_7.txt,val
innovation,5_1,Which of the following options best describe the cover story?,"On the cover: The history of pig domestication is fascinating and closely connected
to agriculture and biomedicine. Throughout history, pigs have primarily been raised
for meat purposes, featured in various popular cuisines worldwide. Advancements in
gene editing technologies have facilitated the rapid development of genetically modified
pigs. For biomedical purposes, researchers can create pig models that accurately mimic
human diseases by introducing targeted genetic modifications, thereby enhancing the
understanding of disease mechanisms and the development of novel therapies. Nowadays,
genetically modified pigs are being explored as potential organ donors for xenotransplantation.",C,MAC_Bench/Cell/Cover/innovation/1_1.png,MAC_Bench/Cell/Cover/innovation/1_1.png,ave_2,1_1.txt,MAC_Bench/Cell/Cover/innovation/4_2.png,MAC_Bench/Cell/Cover/innovation/4_2.png,clip,4_2.txt,MAC_Bench/Cell/Cover/innovation/5_1.png,MAC_Bench/Cell/Cover/innovation/5_1.png,groundtruth,5_1.txt,MAC_Bench/Cell/Cover/innovation/5_5.png,MAC_Bench/Cell/Cover/innovation/5_5.png,vitg,5_5.txt,train
Nature Cancer,5_12,Which of the following options best describe the cover story?,"Lymphatic endothelial-like cells promote glioblastoma
In glioblastoma, lymphatic endothelial-like cells coexist with blood endothelial cells in the brain parenchyma and promote cancer stem cell growth via altered metabolism, providing a therapeutic vulnerability for this deadly disease.
See Zhao et al.
Image: Xinyue Hu, August Fireflies Technology. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Cancer/5_12.png,MAC_Bench/Nature/Cover/Nature Cancer/5_12.png,groundtruth,5_12.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_6.png,MAC_Bench/Nature/Cover/Nature Cancer/5_6.png,clip,5_6.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_3.png,MAC_Bench/Nature/Cover/Nature Cancer/4_3.png,vitg,4_3.txt,MAC_Bench/Nature/Cover/Nature Cancer/1_6.png,MAC_Bench/Nature/Cover/Nature Cancer/1_6.png,vith,1_6.txt,train
Trendsin Neurosciences,47_11,Which of the following options best describe the cover story?,"The locus coeruleus is a small brainstem nucleus that sends
neuromodulatory projections to much of the mammalian brain. As discussed in an
Opinion article by Rebecca Jordan in this issue of Trends in Neurosciences, the locus
coeruleus has recently been shown to report many types of prediction error, making
it
a likely site for reporting global model failures: incidences where the brain’s predictions
about the environment are strongly violated. The cover image shows a mouse locus
coeruleus inside a pupil (an indicator of locus coeruleus activity) monitoring neurons
of the brain (represented as triangles, or stars in the sky) for prediction errors.
Cover
design by Rebecca Jordan; photo credits for the iris image: John M Lund Photography
Inc/Getty Images",B,MAC_Bench/Cell/Cover/Trendsin Neurosciences/36_10.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/36_10.png,ave_2,36_10.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_11.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_11.png,groundtruth,47_11.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/35_2.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/35_2.png,vith,35_2.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_9.png,clip,38_9.txt,train
Nature Photonics,18_7,Which of the following options best describe the cover story?,"Ultrafast tunnelling spectroscopy
Lightwave-driven scanning tunnelling spectroscopy, which combines atomic spatial resolution with sub-picosecond temporal resolution and millielectronvolt energy resolution, enables the analysis of the energy dynamics of a single-atom defect in a 2D material excited by phonons.
See Roelcke et al.
Image: Brad Baxley, PtW. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Photonics/12_9.png,MAC_Bench/Nature/Cover/Nature Photonics/12_9.png,ave_1,12_9.txt,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,clip,6_11.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_7.png,MAC_Bench/Nature/Cover/Nature Photonics/18_7.png,groundtruth,18_7.txt,MAC_Bench/Nature/Cover/Nature Photonics/14_12.png,MAC_Bench/Nature/Cover/Nature Photonics/14_12.png,vith,14_12.txt,train
Accounts of Chemical Research,2024_6,Which of the following options best describe the cover story?,"–organic frameworks, the electronic and electrochemical properties of the constituting components are conserved. Charge is transported by electron hopping between electronically isolated, redox-active components of different oxidation states, a process that is coupled to the diffusion migration of charge balancing counter ions.",A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_6.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_7.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_7.png,vith,2019_7.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2013_8.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2013_8.png,vitg,2013_8.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_19.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_19.png,clip,2022_19.txt,train
ACS Organic & Inorganic Au,2024_4,Which of the following options best describe the cover story?,Zinc(II) Complexes of SIRTi1/2 Analogues Transmetallating with Copper(II) Ions and Inducing ROS Mediated Paraptosis,D,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,groundtruth,2024_4.txt,train
Macromolecules,2024_18,Which of the following options best describe the cover story?,Targeted induction of right- or left-handed double-stranded helical sense in chiral polyelectrolytes through selective choice of configuration in the chiral pendant and with an appropriate counteranion. Authors used Freepik for the cover design.,C,MAC_Bench/ACS/Cover/Macromolecules/2023_23.png,MAC_Bench/ACS/Cover/Macromolecules/2023_23.png,clip,2023_23.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_18.png,MAC_Bench/ACS/Cover/Macromolecules/2022_18.png,vith,2022_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_18.png,MAC_Bench/ACS/Cover/Macromolecules/2024_18.png,groundtruth,2024_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_24.png,MAC_Bench/ACS/Cover/Macromolecules/2010_24.png,vitg,2010_24.txt,val
Nature Reviews Nephrology,20_4,Which of the following options best describe the cover story?,"The ageing world, inspired by the Focus starting on p557.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_2.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_2.png,vitg,19_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_6.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_6.png,clip,19_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_9.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_9.png,vith,19_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_4.png,groundtruth,20_4.txt,train
Nature Geoscience,17_12,Which of the following options best describe the cover story?,"Rare earth elements in circulation
Mobilization of in-use rare earth element stocks in regions of high consumption can ease dependence on regions of rare earth element extraction, according to dynamic integrated modelling combining material flow and scenario analysis. The satellite image shows wind turbines offshore Jiangsu, China, that have magnets containing substantial rare earth elements, representing a potential urban mine for reuse.
See Chen et al.
Image: Chang Guang Satellite Technology. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/Nature Geoscience/17_12.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_12.png,groundtruth,17_12.txt,MAC_Bench/Nature/Cover/Nature Geoscience/5_9.png,MAC_Bench/Nature/Cover/Nature Geoscience/5_9.png,vitg,5_9.txt,MAC_Bench/Nature/Cover/Nature Geoscience/2_8.png,MAC_Bench/Nature/Cover/Nature Geoscience/2_8.png,vith,2_8.txt,MAC_Bench/Nature/Cover/Nature Geoscience/14_4.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_4.png,clip,14_4.txt,val
Cell Chemical Biology,31_4,Which of the following options best describe the cover story?,"On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.",D,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_11.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_11.png,clip,31_11.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png,vitg,31_7.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_15.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_15.png,vith,31_15.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_4.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_4.png,groundtruth,31_4.txt,train
ACS Applied Bio Materials,2024_3,Which of the following options best describe the cover story?,"Esterase-responsive turn-on fluorogenic prodrug of the marketed drug epalrestat was developed towards the treatment of cancer by selectively inhibiting aldose reductases. Activation of the prodrug by intracellular esterases, overexpressed in cancer cells, enables the real-time monitoring of the active drug release (epalrestat) with fluorescence readout.",A,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_2.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_6.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2022_6.png,clip,2022_6.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_12.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2020_12.png,vith,2020_12.txt,train
ACS Sensors,2024_1,Which of the following options best describe the cover story?,"The cover image shows a DMA gas sensor detecting Parkinson's biomarkers, with red MXene nanosheets and yellow Ce ions on the sensor surface. Bubbles represent high humidity, while colored particles depict Ce ion valence states, illustrating enhanced sensitivity and humidity resistance due to the MXene/CeO2 heterojunction and Ce self-refresh mechanism.",B,MAC_Bench/ACS/Cover/ACS Sensors/2017_5.png,MAC_Bench/ACS/Cover/ACS Sensors/2017_5.png,vitg,2017_5.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_1.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Sensors/2022_7.png,MAC_Bench/ACS/Cover/ACS Sensors/2022_7.png,clip,2022_7.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_4.png,vith,2024_4.txt,train
Chemical Research in Toxicology,2024_6,Which of the following options best describe the cover story?,Insights from toxicology. View the article.,C,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2018_12.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2018_12.png,clip,2018_12.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2016_3.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2016_3.png,vitg,2016_3.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_6.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2016_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2016_8.png,vith,2016_8.txt,train
Chem & Bio Engineering,2024_6,Which of the following options best describe the cover story?,"shell structure may be a clever choice to achieve effective capture and storage of radioactive iodine. The core acts as the active site in the reaction with iodine, and the shell acts as a radioactive barrier, trapping captured iodine firmly on the core of the sorbent.",C,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,ave_1,2024_4.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,ave_3,2024_7.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_8.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_8.png,clip,2024_8.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_5,Which of the following options best describe the cover story?,"‘Healing injured tissues’, inspired by the Reviews on p599 and p617
Cover design: Vicky Summersby",A,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_5.png,groundtruth,25_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_2.png,ave_2,22_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,clip,24_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_4.png,vith,23_4.txt,train
ACS Materials Au,2024_3,Which of the following options best describe the cover story?,"Magnetron co-sputtering unlocks a precise control of chemical composition during a high-pressure synthesis in the diamond anvil cell. Chromium cementite is selectively synthesized at high pressures, demonstrating the potential of this novel method. Artwork created by Scott D. Thiel and James P. S. Walsh.",A,MAC_Bench/ACS/Cover/ACS Materials Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_4.png,ave_3,2024_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_6.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_6.png,clip,2022_6.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,vith,2023_2.txt,test
Nature Chemistry,16_7,Which of the following options best describe the cover story?,"Gasoline from plastic waste
Strategies for upcycling waste plastics are urgently required. Now, Han and co-workers have developed a strategy to convert polyethylene into gasoline over a layered self-pillared zeolite without the need for external molecular hydrogen or noble metal catalysts. The reaction proceeds through a self-supplied hydrogen mechanism enabled by the open framework aluminium sites. The cover shows an artistic representation of polyethylene diffusing through zeolite pores and being converted into gasoline.
See Cen et al.
Image: Ziyu Cen and Longfei Lin, Institute of Chemistry, Chinese Academy of Sciences. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Chemistry/10_5.png,MAC_Bench/Nature/Cover/Nature Chemistry/10_5.png,vith,10_5.txt,MAC_Bench/Nature/Cover/Nature Chemistry/4_3.png,MAC_Bench/Nature/Cover/Nature Chemistry/4_3.png,clip,4_3.txt,MAC_Bench/Nature/Cover/Nature Chemistry/4_7.png,MAC_Bench/Nature/Cover/Nature Chemistry/4_7.png,vitg,4_7.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_7.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_7.png,groundtruth,16_7.txt,train
Nature Cell Biology,26_6,Which of the following options best describe the cover story?,"Unconventional secretion
Rab1A, Rab1B and Rab2A regulate TMED10-mediated unconventional protein secretion and compartmentalization of the endoplasmic reticulum–Golgi intermediate compartment (ERGIC).
See Sun, Tao, Han, et al
Image: Courtesy of Rui Xie, Chengdu Great Wall Decoration Design and Color Printing Center, China and Prof Liang Ge, Tsinghua University, China. Cover design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Cell Biology/26_6.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_6.png,groundtruth,26_6.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_10.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_10.png,vith,26_10.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/19_1.png,MAC_Bench/Nature/Cover/Nature Cell Biology/19_1.png,clip,19_1.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/15_11.png,MAC_Bench/Nature/Cover/Nature Cell Biology/15_11.png,vitg,15_11.txt,test
Bioconjugate Chemistry,2025_2,Which of the following options best describe the cover story?,The transfection efficiency of PAMAM dendrimers decorated with a linear fluorinated guanidino linker was studied as a function of the PAMAM generation and the degree of grafting. These multifunctional conjugates showed remarkable transfection efficiency and suitable features for a possible implementation in 19F MRI applications thanks to their sharp and intense fluorine nuclear magnetic resonance signals and favorable relaxation parameters. The cover has been designed by Carola Romani. The MRI apparatus has been created with ChatGPT.,B,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2018_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2018_2.png,vith,2018_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2025_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2010_3.png,clip,2010_3.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_4.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_4.png,vitg,2013_4.txt,train
Accounts of Chemical Research,2024_5,Which of the following options best describe the cover story?,Wireless magnetoelectric neural stimulator next to a blueberry to demonstrate miniaturization.,C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_17.png,ave_2,2022_17.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_8.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_8.png,ave_3,2012_8.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_5.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_9.png,clip,2024_9.txt,train
Chem & Bio Engineering,2024_10,Which of the following options best describe the cover story?,Thermal-triggered non-equilibrium transesterification enables on-demand phosphorescence emission. The modulus change of the polymer is visualized on the basis of the intensity of the phosphorescence. 3D printing of multi-material-structured objects with complex shapes is used to achieve information encryption of printings and on-demand regionally emitted multi-colored phosphorescence.,D,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,ave_1,2024_4.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,vitg,2024_7.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_10.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_10.png,groundtruth,2024_10.txt,train
Nature Machine Intelligence,6_5,Which of the following options best describe the cover story?,"Examining dataset responsibility in machine learning
Machine learning and deep learning algorithms depend on high-quality training data. Mittal et al. present a large audit of computer vision datasets and highlight the vital role of responsible databases in machine learning, emphasizing fairness, privacy and regulatory compliance. These principles are crucial for developing AI systems that are both effective and ethically sound.
See Mittal et al.
Image: Surbhi Mittal, IIT Jodhpur. Cover design: Emily Paul",A,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_5.png,groundtruth,6_5.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_8.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_8.png,vith,4_8.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/7_1.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/7_1.png,clip,7_1.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_12.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_12.png,vitg,2_12.txt,train
ACS ES&T Water,2024_12,Which of the following options best describe the cover story?,"A household sand filter is used in Vietnam for the removal of iron, manganese, and arsenic from groundwater.",D,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_10.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_10.png,vitg,2021_10.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_12.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_12.png,vith,2022_12.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_9.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_9.png,clip,2022_9.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_12.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_12.png,groundtruth,2024_12.txt,test
Nature Synthesis,3_2,Which of the following options best describe the cover story?,"Enzymatic enone synthesis
Chiral enones are produced, using flavin-dependent ene-reductases, through a desymmetrization approach. Enzymatic desaturation and reduction processes enable the synthesis of either enantiomer of the enone products from cyclohexanone or cyclohexadienone substrates.
See Zeng et al.
Image: Mudi Wang, National Institute of Biological Sciences. Cover design: Thomas Phillips",D,MAC_Bench/Nature/Cover/Nature Synthesis/1_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_1.png,vitg,1_1.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_2.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_2.png,ave_2,2_2.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_8.png,clip,1_8.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_2.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_2.png,groundtruth,3_2.txt,train
Developmental Cell,59_14,Which of the following options best describe the cover story?,"On the cover: The image illustrates the idea of light-induced mechanical forces applied
to the endoplasmic reticulum (ER) network. The robotic hands, glowing with shimmering
blue light, symbolize the optogenetic mechanostimulator. Upon light illumination,
the hands pull and thus stretch the ER. To learn more about the molecular details
of the ER-specific optogenetic mechanostimulator and insights into ER mechanosensitivity,
see Song et al. Image credit: Liting Duan and Qianjing Studio.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_14.png,MAC_Bench/Cell/Cover/Developmental Cell/59_14.png,groundtruth,59_14.txt,MAC_Bench/Cell/Cover/Developmental Cell/23_5.png,MAC_Bench/Cell/Cover/Developmental Cell/23_5.png,clip,23_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/58_11.png,MAC_Bench/Cell/Cover/Developmental Cell/58_11.png,vitg,58_11.txt,MAC_Bench/Cell/Cover/Developmental Cell/56_14.png,MAC_Bench/Cell/Cover/Developmental Cell/56_14.png,vith,56_14.txt,train
Accounts of Materials Research,2024_7,Which of the following options best describe the cover story?,"CO2 electrolysis driven by sustainable energy resources is an attractive way to close the carbon cycle and achieve carbon neutrality. This Account highlights recent advances in cathode materials design for CO2 electrolysis from room to elevated temperatures, with a focus on various strategies.",C,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_4.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_4.png,ave_1,2024_4.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_7.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_7.png,ave_2,2023_7.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_7.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_1.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_1.png,clip,2022_1.txt,train
NATURE REVIEWS GENETICS,25_5,Which of the following options best describe the cover story?,"Inspired by the Review on p534
Cover design: Patrick Morgan",A,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_5.png,groundtruth,25_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/13_4.png,vitg,13_4.txt,test
Developmental Cell,59_10,Which of the following options best describe the cover story?,"On the cover: The image depicts the mitochondrial network as the tree of life. When
our cells are young, mitophagy constantly works to prune its branches and keep the
tree healthy. In this abstraction, mitophagy events are depicted as spheres emanating
from the tree on the left. With age, mitophagy stops working, leaving behind the old
fruitless deadwood which can no longer support cellular functions (as visualized by
the tree on the right). To learn more about how loss of mitochondrial quality control
drives aging, see Kelly et al. Image credit: Hanna Salmonowicz.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_10.png,MAC_Bench/Cell/Cover/Developmental Cell/59_10.png,groundtruth,59_10.txt,MAC_Bench/Cell/Cover/Developmental Cell/57_8.png,MAC_Bench/Cell/Cover/Developmental Cell/57_8.png,clip,57_8.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_24.png,MAC_Bench/Cell/Cover/Developmental Cell/59_24.png,vitg,59_24.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_7.png,MAC_Bench/Cell/Cover/Developmental Cell/59_7.png,vith,59_7.txt,val
Nature Astronomy,8_9,Which of the following options best describe the cover story?,"Sun-a-day diet for luminous quasar
A heavyweight black hole, embedded within quasar SMSS J052915.80−435152.0 at a redshift of z ≈ 4, is accreting a solar mass of material every day. The process releases 2 × 1041 W of power, meaning that this quasar currently holds the title of most luminous quasar known.
See Wolf et al.
Image: ESO/M. Kornmesser, Cristy Roberts, Australian National University. Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Astronomy/8_9.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_9.png,groundtruth,8_9.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,vith,1_2.txt,MAC_Bench/Nature/Cover/Nature Astronomy/3_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/3_1.png,vitg,3_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,clip,1_1.txt,train
Nature Astronomy,8_5,Which of the following options best describe the cover story?,"Studying accretion in extreme regimes
The Imaging X-ray Polarimetry Explorer has observed renowned Galactic X-ray binary Cygnus X-3, receiving photons reflected from the accretion funnel around the compact component. Accretion occurs at super-Eddington rates; the apparent luminosity makes Cygnus X-3 an ultraluminous X-ray source.
See Veledina et al.
Image: Alexander Mushtukov, University of Oxford (alexander.mushtukov@physics.ox.ac.uk). Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Astronomy/3_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/3_1.png,ave_2,3_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,vitg,1_2.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_5.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_5.png,groundtruth,8_5.txt,train
One Earth,7_12,Which of the following options best describe the cover story?,"On the cover: Scientific journals can play an important role in the curation and communication
of key scientific advances and expert opinions. But as the scientific literature and
number of publication platforms continue to expand, it can be easy to lose sight of
these important functions. Image: Eoneren, Getty.",D,MAC_Bench/Cell/Cover/One Earth/5_4.png,MAC_Bench/Cell/Cover/One Earth/5_4.png,ave_1,5_4.txt,MAC_Bench/Cell/Cover/One Earth/6_9.png,MAC_Bench/Cell/Cover/One Earth/6_9.png,vitg,6_9.txt,MAC_Bench/Cell/Cover/One Earth/4_3.png,MAC_Bench/Cell/Cover/One Earth/4_3.png,clip,4_3.txt,MAC_Bench/Cell/Cover/One Earth/7_12.png,MAC_Bench/Cell/Cover/One Earth/7_12.png,groundtruth,7_12.txt,train
ACS Catalysis,2024_22,Which of the following options best describe the cover story?,"This study modifies the ZSM-5 zeolite support of Au/ZSM-5 catalysts through desilication-recrystallization to increase activity for partial methane oxidation. The treatment notably enhances oxygenate yield, primarily of methanol and acetic acid, by redistributing acid sites across the zeolite surface and stabilizing gold nanoparticles.",B,MAC_Bench/ACS/Cover/ACS Catalysis/2022_23.png,MAC_Bench/ACS/Cover/ACS Catalysis/2022_23.png,vith,2022_23.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_22.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2015_1.png,MAC_Bench/ACS/Cover/ACS Catalysis/2015_1.png,vitg,2015_1.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2011_12.png,MAC_Bench/ACS/Cover/ACS Catalysis/2011_12.png,clip,2011_12.txt,train
Nature Reviews Clinical Oncology,21_12,Which of the following options best describe the cover story?,"Using computational tools to predict response to immunotherapies, inspired by the Review on p28.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_2.png,clip,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,vith,19_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_7.png,ave_0,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_12.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_12.png,groundtruth,21_12.txt,train
Nature Cancer,5_11,Which of the following options best describe the cover story?,"Dendritic cells for cancer immunotherapy
A cell-therapy platform based on dendritic cell progenitors that express immunostimulatory cytokines has shown anti-tumor efficacy in melanoma and liver cancer models in an antigen-agnostic manner.
See Ghasemi et al.
Image: Amaia Martinez-Usatorre/Michele De Palma/EPFL. Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Cancer/5_12.png,MAC_Bench/Nature/Cover/Nature Cancer/5_12.png,clip,5_12.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_11.png,MAC_Bench/Nature/Cover/Nature Cancer/5_11.png,groundtruth,5_11.txt,MAC_Bench/Nature/Cover/Nature Cancer/2_8.png,MAC_Bench/Nature/Cover/Nature Cancer/2_8.png,vith,2_8.txt,MAC_Bench/Nature/Cover/Nature Cancer/3_10.png,MAC_Bench/Nature/Cover/Nature Cancer/3_10.png,vitg,3_10.txt,train
Nature Ecology & Evolution,8_8,Which of the following options best describe the cover story?,"Social transmission
Social behaviour among wild wood mice (Apodemus sylvaticus) provides a way to share microbes. Their social networks are an important transmission route for anaerobic gut microbes, whereas more oxygen-tolerant gut microbes spread through shared environments instead.
See Raulo et al
Image: Roy and Marie Battell. Cover Design: Allen Beattie.",B,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_11.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_11.png,vitg,8_11.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,groundtruth,8_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_1.png,clip,4_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/3_5.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/3_5.png,vith,3_5.txt,train
Cell Chemical Biology,31_6,Which of the following options best describe the cover story?,"On the cover: Dual targeting of proteins (orange and blue) on the same cell surface
via bispecific antibodies (pink beige) holds great therapeutic promise with novel
modes of action that are rapidly advancing towards the clinic. Oslund et al. review the therapeutic impact of cis-targeting bispecific antibodies (pink beige)
in the clinic and their emerging applications and highlight features for enhancing
cis-targeting bispecific therapeutic development. Cover art created by Yi Zheng (yizhengillustration).",A,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_6.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_6.png,groundtruth,31_6.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_12.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_12.png,clip,31_12.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/24_3.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/24_3.png,vitg,24_3.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_9.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/18_9.png,vith,18_9.txt,test
Biomacromolecules,2024_2,Which of the following options best describe the cover story?,"In this work, endothelium-mimicking surfaces were constructed by integrating the antifouling properties, glycosaminoglycan analogs, and nitric oxide generation capabilities characteristic of a healthy endothelium. By regulating different functional components, an elegant balance between antifouling properties and endothelial cell selectivity was achieved on the silicone surface.",C,MAC_Bench/ACS/Cover/Biomacromolecules/2021_2.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_2.png,vitg,2021_2.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_5.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_5.png,ave_2,2021_5.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_2.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2022_5.png,MAC_Bench/ACS/Cover/Biomacromolecules/2022_5.png,clip,2022_5.txt,test
Nature Cardiovascular Research,3_12,Which of the following options best describe the cover story?,"Shift in cardiometabolic and renal phenotypes in the US population
Lhoste et al. show that cardiometabolic and renal traits of the US population have shifted from phenotypes with high blood pressure and high cholesterol towards poor kidney function, hyperglycemia and severe obesity.
See Lhoste et al.
Cover image: Tree: marumaru / iStock / Getty Images Plus. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_2.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_2.png,vitg,1_2.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_12.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_12.png,groundtruth,3_12.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_12.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_12.png,vith,1_12.txt,train
Nature Chemical Engineering,1_2,Which of the following options best describe the cover story?,"Electrified processing of carbonates to ethylene
Industrial processes for the electrochemical production of ethylene from aqueous carbonate feedstocks are not well understood. Now, Sankar Nair and co-workers report process simulations and a techno-economic analysis to identify barriers to the future commercialization of this technology as well as advances needed to make the process feasible. The image illustrates an industrial-scale process designed to produce ethylene from carbon dioxide captured from the air through electrochemical reduction. It shows the flow of various species between the units in the process. It also highlights the complexities involved in optimizing the economics and evaluating the uncertainties of the process using computational approaches.
See Venkataraman et al.
Image: Anush Venkataraman, Georgia Institute of Technology. Cover design: Laoise Mac Gabhann.",C,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png,vitg,1_12.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_2.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_2.png,groundtruth,1_2.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_8.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_8.png,vith,1_8.txt,train
Industrial & Engineering Chemistry Research,2024_16,Which of the following options best describe the cover story?,Anionization artificially modulated to increase electron cloud density and enhance intermolecular forces between amine with carbon dioxide.,A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,groundtruth,2024_16.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_11.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_11.png,clip,2023_11.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_13.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_13.png,vith,2022_13.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_35.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_35.png,vitg,2023_35.txt,train
Science Robotics,9_90,Which of the following options best describe the cover story?,"ONLINE COVER A Lens-Free Compound Eye. The wide field of view and motion tracking capabilities of insect eyes are attractive features to roboticists, but have been difficult to replicate when transferring lenses to a curved surface. Taking inspiration from a robber fly’s eye, Zhou et al. developed a lens-free pinhole compound eye with a perovskite nanowire photodetector array. This pinhole compound eye exhibited a wide field of view and dynamic motion tracking. This month’s cover shows a fusion of an image composite of a robber fly’s eye on the left and an illustration of the pinhole compound eye on the right. Credit: Beijing Fantastic Color Animation Technology Co., Ltd., and Muhammad Roem",A,MAC_Bench/Science/Cover/Science Robotics/9_90.png,MAC_Bench/Science/Cover/Science Robotics/9_90.png,groundtruth,9_90.txt,MAC_Bench/Science/Cover/Science Robotics/6_56.png,MAC_Bench/Science/Cover/Science Robotics/6_56.png,clip,6_56.txt,MAC_Bench/Science/Cover/Science Robotics/7_66.png,MAC_Bench/Science/Cover/Science Robotics/7_66.png,vitg,7_66.txt,MAC_Bench/Science/Cover/Science Robotics/3_22.png,MAC_Bench/Science/Cover/Science Robotics/3_22.png,vith,3_22.txt,train
Nature Cardiovascular Research,3_9,Which of the following options best describe the cover story?,"Histone H1.0 links cell mechanics to chromatin structure
Hu et al. describe how histone H1.0 regulates cellular responses to mechanical stimulation, inducing myofibroblast activation in the heart and linking force generation to nuclear organization and gene transcription.
See Hu et al.
Image: Todd H. Kimball, PhD, UCLA/UNC Chapel Hill. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vith,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_9.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_9.png,groundtruth,3_9.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,clip,2_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_11.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_11.png,vitg,3_11.txt,train
Nature Machine Intelligence,6_8,Which of the following options best describe the cover story?,"Generating quantum circuits
Quantum computing promises to be a transformative technology, but there are several challenges in realizing quantum computing hardware. One is the generation of quantum circuits that perform desired operations. Denoising diffusion models excel at this task, providing a powerful and flexible method to create circuits in a variety of scenarios. Given a text prompt that describes a quantum operation, they rely on iteratively denoising an initially noisy canvas until the desired quantum circuit is reached.
See Fürrutter et al.
Image: Harald Ritsch. Cover design: Amie Fernandez",D,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/3_5.png,vitg,3_5.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_6.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/4_6.png,clip,4_6.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_11.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/5_11.png,ave_1,5_11.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_8.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_8.png,groundtruth,6_8.txt,train
Chem & Bio Engineering,2024_7,Which of the following options best describe the cover story?,The membranes made from light-responsive ionic covalent-organic frameworks show improved ionic power generation by capitalizing on the synergistic effects of solar energy and salinity gradients.,B,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_8.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,ave_1,2024_4.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_5.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_5.png,ave_2,2024_5.txt,train
Nature Reviews Clinical Oncology,21_10,Which of the following options best describe the cover story?,"Improving anticancer activity of antibody–drug conjugates, inspired by the Review on p203.
Cover design: Lara Crow",C,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_5.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_5.png,vitg,20_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_10.png,groundtruth,21_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/19_10.png,vith,19_10.txt,train
CELL RESEARCH,34_10,Which of the following options best describe the cover story?,"The Chinese legend “The Butterfly Lovers”, also known as “Liang Zhu”, depicts two lovers transformed to butterflies. The butterflies symbolize the gray matter of the human spinal cord with well-organized cells in the dorsal and ventral horns. This imagery beautifully conveys the idea of transformation from embryonic to adult spinal cord. See page 193–213 by Yingchao Shi et al. for details.",B,MAC_Bench/Nature/Cover/CELL RESEARCH/31_4.png,MAC_Bench/Nature/Cover/CELL RESEARCH/31_4.png,vitg,31_4.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,groundtruth,34_10.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_5.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_5.png,clip,32_5.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/33_9.png,MAC_Bench/Nature/Cover/CELL RESEARCH/33_9.png,ave_3,33_9.txt,val
Nature Reviews Neurology,21_2,Which of the following options best describe the cover story?,"Brain diet, inspired by the Review on p5
Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_11.png,ave_3,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_2.png,groundtruth,21_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_6.png,ave_2,20_6.txt,val
NATURE REVIEWS DRUG DISCOVERY,24_2,Which of the following options best describe the cover story?,"N-of-1 therapies, inspired by the Review on p40.
Cover design: S. Harris",B,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/24_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/24_2.png,groundtruth,24_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_12.png,vitg,21_12.txt,train
Nature Astronomy,8_4,Which of the following options best describe the cover story?,"Pulsar-like or pulsar-unlike?
A rare long-period transient detected by CSIRO’s ASKAP radio telescope could be either a neutron star or white dwarf emitting in an unusual way. These two possibilities are represented here. In either case, the source is a member of an under-explored population of radio transients.
See Caleb et al.
Image: Carl Knox, OzGrav – Swinburne University of Technology. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Astronomy/6_7.png,MAC_Bench/Nature/Cover/Nature Astronomy/6_7.png,vith,6_7.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_4.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_4.png,groundtruth,8_4.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_2.png,clip,2_2.txt,MAC_Bench/Nature/Cover/Nature Astronomy/5_3.png,MAC_Bench/Nature/Cover/Nature Astronomy/5_3.png,vitg,5_3.txt,val
Nature Structural & Molecular Biology,31_9,Which of the following options best describe the cover story?,"Disentangling channel-gating mechanisms
Kalienkova et al. report high-resolution structures of an FMRFamide-gated sodium channel in several functional states. This disentangles the molecular basis by which different invertebrate receptors recognize similar neuropeptides and paves the way for studies of channel gating and ion conduction among the degenerin/epithelial sodium channel superfamily.
See Kalienkova et al.
IMAGE CREDIT: Alexandre Jan, University of Bergen. COVER DESIGN: Allen Beattie",D,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_12.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_12.png,clip,28_12.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_11.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/25_11.png,vith,25_11.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,vitg,28_8.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_9.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_9.png,groundtruth,31_9.txt,train
JACS Au,2024_9,Which of the following options best describe the cover story?,Using the biomolecule DNA to tether porphyrin-based electrocatalysts to electrode surfaces improves their efficiency for carbon dioxide valorization.,A,MAC_Bench/ACS/Cover/JACS Au/2024_9.png,MAC_Bench/ACS/Cover/JACS Au/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/JACS Au/2021_12.png,MAC_Bench/ACS/Cover/JACS Au/2021_12.png,vitg,2021_12.txt,MAC_Bench/ACS/Cover/JACS Au/2021_3.png,MAC_Bench/ACS/Cover/JACS Au/2021_3.png,ave_1,2021_3.txt,MAC_Bench/ACS/Cover/JACS Au/2023_3.png,MAC_Bench/ACS/Cover/JACS Au/2023_3.png,clip,2023_3.txt,train
Macromolecules,2024_5,Which of the following options best describe the cover story?,An autoencoder-based classifier recognizes early crystalline nuclei formed during a molecular dynamics cooling cycle. The decision boundary between crystalline and amorphous phases is identified autonomously within the conformation space,B,MAC_Bench/ACS/Cover/Macromolecules/2020_7.png,MAC_Bench/ACS/Cover/Macromolecules/2020_7.png,ave_2,2020_7.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_5.png,MAC_Bench/ACS/Cover/Macromolecules/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2020_13.png,MAC_Bench/ACS/Cover/Macromolecules/2020_13.png,clip,2020_13.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_14.png,MAC_Bench/ACS/Cover/Macromolecules/2022_14.png,vitg,2022_14.txt,train
Accounts of Materials Research,2024_6,Which of the following options best describe the cover story?,"Emulating natural photosynthesis, artificial leaves constructed with semiconductor photoelectrodes harness solar energy to convert water, carbon dioxide, etc. into valuable fuels/chemicals. This Account describes recent advancements in silicon-based photoelectrodes, emphasizing innovative design and integration solutions for practical artificial photosynthesis.",D,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_2.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_2.png,vith,2022_2.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_7.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2021_7.png,vitg,2021_7.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_1.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_1.png,clip,2022_1.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_6.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_6.png,groundtruth,2024_6.txt,test
Nature Structural & Molecular Biology,31_11,Which of the following options best describe the cover story?,"Understanding writers and readers of ubiquitylation
In this issue, we feature seven studies that progress our understanding of writers and readers of ubiquitylation, in addition to a Historical Perspective and several Comment pieces reflecting on the ever-expanding roles of this critical modification.
See Editorial
IMAGE CREDIT: Linda Marie Caldwell / iStock / Getty Images Plus. COVER DESIGN: Allen Beattie",D,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_5.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_5.png,vith,30_5.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_12.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_12.png,clip,28_12.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_2.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_2.png,vitg,26_2.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_11.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_11.png,groundtruth,31_11.txt,train
Cell Stem Cell,31_8,Which of the following options best describe the cover story?,"On the cover: In this issue, Sun et al. report that the neonatal spinal cord extracellular matrix (ECM) provides developmental
cues for spinal cord neural progenitor cells and organoids to promote host-graft neural
connections, thereby enhancing the therapeutic effects on spinal cord injury. Their
findings suggest that the remarkable regenerative ability of the neonatal spinal cord
may stem from its favorable ECM environment. The cover shows the neonatal spinal cord
ECM molecular “workers” connecting the axonal “cables” of the organoid spheroids to
spinal cord “plugs” to rebuild the neural network. Image courtesy of the authors.",B,MAC_Bench/Cell/Cover/Cell Stem Cell/7_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/7_4.png,clip,7_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_8.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_8.png,groundtruth,31_8.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/24_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/24_1.png,vith,24_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,vitg,6_4.txt,train
ACS Nanoscience Au,2024_3,Which of the following options best describe the cover story?,"The strategic coating of Cu/ZrO2/In2O3 and Cu/CeO2/In2O3 catalysts with mesoporous SiO2 creates a maze-like environment during CO2 hydrogenation. This environment allows reactant molecules to move freely until they reach the active sites. Even under challenging reaction conditions, the physical constraints effectively prevent nanoparticles from sintering, ensuring consistent performance.",B,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_5.png,clip,2023_5.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_2.png,vitg,2024_2.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_4.png,ave_3,2022_4.txt,test
Precision Chemistry,2024_3,Which of the following options best describe the cover story?,"Unlocking new frontiers in medical diagnostics, drug discovery, and environmental monitoring, AI-integrated single-molecule bioelectronic sensors, including nanogapped electrodes and nanopores, deliver unprecedented precision, efficiency, and profound insights into complex biological processes.",A,MAC_Bench/ACS/Cover/Precision Chemistry/2024_3.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_10.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2025_2.png,MAC_Bench/ACS/Cover/Precision Chemistry/2025_2.png,vith,2025_2.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_2.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_2.png,clip,2023_2.txt,train
Journal of the American Chemical Society,2024_1,Which of the following options best describe the cover story?,"This study shows an interfacial electric-field-induced prototropic tautomerization reaction in an enzymatic-like nanopocket created by the atomically sharp gold electrodes using the mechanically controlled break junction (MCBJ) technique. The mechanistic studies revealed a proton relay-assisted tautomerization, showing the importance of external factors, like solvent, in electric-field-driven reactions. View the article.",A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_1.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_41.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_41.png,vitg,2011_41.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_51.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_51.png,clip,2018_51.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_21.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_21.png,vith,2011_21.txt,test
Chemical Research in Toxicology,2024_2,Which of the following options best describe the cover story?,"The cover graphic features a computer displaying in silico toxicology research on Bromo-DragonFLY, highlighting its potential acute toxicity, genotoxicity, cardiotoxicity, and endocrine disruption in comparison to forensic toxicology. Part of this cover was generated using the AI programs, DALL-E via ChatGPT 4 and PSD AI.",D,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_2.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_2.png,vith,2012_2.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_11.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_11.png,vitg,2024_11.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2014_4.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2014_4.png,clip,2014_4.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_2.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_2.png,groundtruth,2024_2.txt,train
Chemical & Biomedical ImagingOpen Access,2024_10,Which of the following options best describe the cover story?,A label-free 3D tomogram of COVID-19 microclots was recorded using a digital holotomographic microscope.,B,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_10.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_7.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,vith,2023_1.txt,test
Nature Reviews Materials,10_2,Which of the following options best describe the cover story?,"Tissue biomechanics provides essential biological information that is important for various biomedical applications, and conformable electronic devices are instrumental for decoding this information. The cover shows an artist’s impression of island-bridge structures, consisting of rigid functional ""islands"" connected by flexible ""bridges"", which allow devices to be stretched or bent without losing functionality. See Yoon H. et al.
Cover: David Johnston",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,vitg,9_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_7.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/2_7.png,vith,2_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/10_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/10_2.png,groundtruth,10_2.txt,train
ACS Food Science & Technology,2024_6,Which of the following options best describe the cover story?,"This cover, in part created using the ""Canva"" AI tool, represents the focus of our study, a chickpea plant, treated with foliar application of wood distillate. Seeds were used to obtain a fortified flour, employed for the development of functional bakery products, like cookies. Additionally, it includes a graph containing a flavonoid found in the flour and a model of the simulated gastrointestinal digestion to obtain available peptides.",D,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_7.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_8.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_8.png,ave_1,2022_8.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_5.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_5.png,ave_2,2022_5.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_6.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_6.png,groundtruth,2024_6.txt,train
Macromolecules,2024_14,Which of the following options best describe the cover story?,"Tröger's base-derived benzoxazine was synthesized using a continuous three-step approach from 2,8-dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5] diazocine-3,9-diamine with no intermediates isolation or purification. Ring-opening polymerization transformed it into a polymer with intrinsic microporosity. The obtained polymer was fluorescent only in the solid state. When the curing temperature rose, the polymer emission maximum shifted red.",A,MAC_Bench/ACS/Cover/Macromolecules/2024_14.png,MAC_Bench/ACS/Cover/Macromolecules/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_12.png,MAC_Bench/ACS/Cover/Macromolecules/2012_12.png,clip,2012_12.txt,MAC_Bench/ACS/Cover/Macromolecules/2012_11.png,MAC_Bench/ACS/Cover/Macromolecules/2012_11.png,vitg,2012_11.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_17.png,MAC_Bench/ACS/Cover/Macromolecules/2014_17.png,ave_1,2014_17.txt,train
CELL RESEARCH,34_9,Which of the following options best describe the cover story?,"The cover image illustrates the aluminum (Al) ion receptor ALR1 (Beacon Tower)that senses toxic aluminum ions, inducing reactive oxygen species (ROS; smoke) generation and accumulation of STOP1 (commander),thereby activating organic acid anion (arrow) secretion to detoxify Al. See page 281–294 by Zhong Jie Ding et al. for details.",C,MAC_Bench/Nature/Cover/CELL RESEARCH/33_1.png,MAC_Bench/Nature/Cover/CELL RESEARCH/33_1.png,vith,33_1.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/30_9.png,MAC_Bench/Nature/Cover/CELL RESEARCH/30_9.png,vitg,30_9.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_9.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_9.png,groundtruth,34_9.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/33_6.png,MAC_Bench/Nature/Cover/CELL RESEARCH/33_6.png,clip,33_6.txt,train
Cell Reports Physical Science,5_2,Which of the following options best describe the cover story?,"On the cover: Baker and Alvarez investigated local pH modification for urea electro-oxidation in bulk-neutral media.
The image shows co-located electrodes with gas bubbles generated on the surface. It
is reminiscent of hydrogen evolution during the urea electro-oxidation reaction on
interdigitated electrodes. The color gradient is a reference to the simulation results
depicting pH variation along the surface. The image was created by Mr. Eric Proctor,
Visual Information Specialist at DEVCOM Army Research Laboratory.",D,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_3.png,clip,1_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_8.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_8.png,ave_2,1_8.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,vith,2_9.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_2.png,groundtruth,5_2.txt,train
Cell Chemical Biology,31_9,Which of the following options best describe the cover story?,"On the cover: Two pathways (umbrellas) are responsible for NAD+ production in mammalian
cells: the NAPRT-mediated biosynthesis pathway and the NAMPT-mediated salvage pathway.
Zhu et al. develop and assess a second generation PROTAC (rain drops) that degrades and functionally
inactivates NAMPT, leading to the death of NAMPT-positive tumor cells exclusively
relying on the salvage pathway (right fire). In contrast, cells expressing NAPRT are
capable of using nicotinic acid to synthesize NAD+ and are resistant to the effects
of the NAMPT-targeting PROTAC (left fire).",C,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_10.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_10.png,clip,31_10.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/16_12.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/16_12.png,ave_3,16_12.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_9.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_9.png,groundtruth,31_9.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_1.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_1.png,vitg,19_1.txt,train
NATURE METHODS,21_2,Which of the following options best describe the cover story?,"Microscopic art
An image of a section of small intestine from a mouse won fourth place in the Nikon Small World 2024 Photomicrography competition.
See Editorial
Image: Amy Engevik, Medical University of South Carolina. Cover design: Thomas Phillips",D,MAC_Bench/Nature/Cover/NATURE METHODS/20_11.png,MAC_Bench/Nature/Cover/NATURE METHODS/20_11.png,vitg,20_11.txt,MAC_Bench/Nature/Cover/NATURE METHODS/16_10.png,MAC_Bench/Nature/Cover/NATURE METHODS/16_10.png,clip,16_10.txt,MAC_Bench/Nature/Cover/NATURE METHODS/7_1.png,MAC_Bench/Nature/Cover/NATURE METHODS/7_1.png,vith,7_1.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_2.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_2.png,groundtruth,21_2.txt,test
Nature Microbiology,9_6,Which of the following options best describe the cover story?,"Unravelling diet–microbiome interactions
This image depicts a Rube Goldberg-type representation of the gut microbiota, playfully showing the process of converting various food items into metabolites. In this issue, Quinn-Bohmann et al. have developed a community-scale metabolic modelling approach for predicting personalized short-chain fatty acid production by the gut microbiota in response to prebiotic, probiotic and dietary inputs. Butyrate, a short-chain fatty acid of interest in the paper, is featured as golden stick figures towards the bottom of the composition.
See Quinn-Bohmann et al.
Image: Sam D'Orazio and Institute for Systems Biology (ISB). Cover design: Debbie Maizels",D,MAC_Bench/Nature/Cover/Nature Microbiology/3_9.png,MAC_Bench/Nature/Cover/Nature Microbiology/3_9.png,vith,3_9.txt,MAC_Bench/Nature/Cover/Nature Microbiology/8_10.png,MAC_Bench/Nature/Cover/Nature Microbiology/8_10.png,clip,8_10.txt,MAC_Bench/Nature/Cover/Nature Microbiology/2_4.png,MAC_Bench/Nature/Cover/Nature Microbiology/2_4.png,vitg,2_4.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_6.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_6.png,groundtruth,9_6.txt,train
Nature Reviews Chemistry,9_1,Which of the following options best describe the cover story?,"Synthetic molecular cages are three-dimensional structures that are designed to recognize and bind specific molecules. Much like a key fitting into a lock, the cage captures molecules based on their size and shape. Researchers are especially interested in how these cages can help identify different sugars. Such cages can be useful in a variety of applications in science and medicine, from chemical detection to drug delivery, see Wu et al.
Image: Carl Conway; Cover design: Carl Conway",C,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/3_1.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/3_1.png,ave_1,3_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/5_6.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/5_6.png,clip,5_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/9_1.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_11.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_11.png,ave_2,6_11.txt,val
Nature Nanotechnology,19_7,Which of the following options best describe the cover story?,"Multiparametric nano-mechanobiology of neurons
The cover image depicts a coloured scanning electron microscopy image of a network of cortical neurons grown on a microelectrode array used for combined force and electrophysiological measurements.
See Muller et al.
Image: M. Oeggerli (Micronaut) 2020–2024, supported by University Hospital Basel (Pathology), Bio-EM Lab, Biozentrum, University Basel, and S. Ronchi and A. Hierlemann, Bio-Engineering Laboratory, D-BSSE, ETH Zurich. Cover design: Debbie Maizels",A,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_7.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_7.png,groundtruth,19_7.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_7.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_7.png,vitg,18_7.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_5.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_5.png,vith,11_5.txt,train
Nature Computational Science,5_1,Which of the following options best describe the cover story?,"Energy-efficient large language models
Implementing artificial intelligence (AI) models, such as large language models (LLMs), on conventional von Neumann computing hardware — which separates memory and computing — is notoriously energy and power intensive. In this issue, Abu Sebastian and colleagues demonstrate that devices based on non-volatile memory (a type of analog in-memory computing hardware), constructed in three dimensions (3D), could substantially improve the energy efficiency of LLMs by leveraging ‘mixture of experts’ (MoEs) models. The cover image depicts MoEs neural networks realized through 3D analog in-memory computing on a silicon microchip, with multiple stacked tiers representing the experts in the network.
See Büchel et al. and Anand Subramoney
Image: Jeongung Cho, CUBE3D Graphic. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,vitg,4_8.txt,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,groundtruth,5_1.txt,MAC_Bench/Nature/Cover/Nature Computational Science/1_7.png,MAC_Bench/Nature/Cover/Nature Computational Science/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_2.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_2.png,vith,4_2.txt,train
Nature Physics,20_4,Which of the following options best describe the cover story?,"Digital braiding of Fibonacci anyons
Anyons are particles that do not follow either Bose or Fermi statistics and can be found in quantum many-body systems that have a non-Abelian topological order. They can be used to encode and manipulate quantum information in a topologically protected manner, meaning that they are robust against some types of noise. Shibo Xu et al. have used a superconducting quantum processor to simulate non-Abelian topologically ordered states of the Fibonacci string-net model and demonstrate both braiding and fusion of Fibonacci anyons — operations that are required to implement quantum gates.
See Xu et al.
Image: Shibo Xu, Jiachen Chen, Zheng-Zhi Sun. Cover design: Emily Paul",B,MAC_Bench/Nature/Cover/Nature Physics/18_8.png,MAC_Bench/Nature/Cover/Nature Physics/18_8.png,vitg,18_8.txt,MAC_Bench/Nature/Cover/Nature Physics/20_4.png,MAC_Bench/Nature/Cover/Nature Physics/20_4.png,groundtruth,20_4.txt,MAC_Bench/Nature/Cover/Nature Physics/17_6.png,MAC_Bench/Nature/Cover/Nature Physics/17_6.png,clip,17_6.txt,MAC_Bench/Nature/Cover/Nature Physics/19_10.png,MAC_Bench/Nature/Cover/Nature Physics/19_10.png,vith,19_10.txt,test
Journal of the American Chemical Society,2024_44,Which of the following options best describe the cover story?,"While molecular marodipoles on average do not vary much with time (red line on the graph), they show huge picosecond fluctuations due to solvent dynamics (white line on the graph).  View the article.",C,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_41.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2011_41.png,clip,2011_41.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2012_16.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2012_16.png,ave_2,2012_16.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_44.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_44.png,groundtruth,2024_44.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2012_14.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2012_14.png,ave_1,2012_14.txt,train
Nature Reviews Chemistry,8_11,Which of the following options best describe the cover story?,"Solar reforming is the sunlight-driven transformation of waste feedstocks into valuable fuels and chemicals. It encompasses a set of emerging technologies that have the potential to support the energy and chemical industries as they transition towards a sustainable circular economy. This review discusses the concept, configurations and metrics of solar reforming, and proposes future directions. The cover depicts an artistic rendition of a solar reforming reactor where sunlight drives the simultaneous conversion of carbon dioxide to fuels and solid waste to chemicals. See Bhattacharjee et al.
Image: Sayan Kar, Motiar Rahaman, Chanon Pornrungroj Cover design: Carl Conway",B,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_4.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_4.png,vith,6_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_11.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_11.png,groundtruth,8_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_10.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_10.png,ave_1,8_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_2.png,clip,8_2.txt,train
NATURE BIOTECHNOLOGY,42_4,Which of the following options best describe the cover story?,"Sensing m6A in cells
A representation of cellular mRNA modified by m6A, which is depicted as a gemstone. Marayati et al. develop GEMS, a genetically encoded m6A sensor that can report changes in m6A in living cells.
See Marayati et al.
Image: iStock.com/CROCOTHERY. Further modification by Kate Meyer (Duke University). Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_9.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/41_9.png,ave_0,41_9.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_4.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_4.png,groundtruth,42_4.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/40_11.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/40_11.png,vith,40_11.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/26_8.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/26_8.png,clip,26_8.txt,train
Nature Astronomy,8_1,Which of the following options best describe the cover story?,"Galaxies from wherever flock together
Streamlines trace the motions of galaxies through the Universe from their modern-day locations to the potential minima of basins of attraction.
See Valade et al.
Image: Daniel Pomarède, Institut de Recherche sur les Lois Fondamentales de l’Univers, CEA, Université Paris-Saclay. Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Astronomy/8_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_1.png,groundtruth,8_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/6_6.png,MAC_Bench/Nature/Cover/Nature Astronomy/6_6.png,vitg,6_6.txt,MAC_Bench/Nature/Cover/Nature Astronomy/6_9.png,MAC_Bench/Nature/Cover/Nature Astronomy/6_9.png,ave_2,6_9.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,clip,2_1.txt,val
Precision Chemistry,2024_9,Which of the following options best describe the cover story?,"With a copper electrode background, the cover describes the process of carbon deposition leading to electrode poisoning in the carbon dioxide reduction reaction process. The carbon accumulation on the electrode surface is irregularly distributed, and the hydrogen evolution reaction is intensified.",B,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_9.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,vith,2024_4.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_8.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_8.png,vitg,2023_8.txt,train
Nature Cancer,5_10,Which of the following options best describe the cover story?,"γδ T cells as a target of checkpoint inhibition
Intratumoral PD-1+Vγ1+ cells display an exhaustion program similar to that of αβ T cells, can be derepressed by checkpoint inhibitors and are predictive of the response to anti-PD-1 in patients with melanoma, specifically those with low levels of neoantigens.
See Davies et al.
Image credit: Joe Brock, Research Illustration Manager, The Francis Crick Institute Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Cancer/3_10.png,MAC_Bench/Nature/Cover/Nature Cancer/3_10.png,vitg,3_10.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_10.png,MAC_Bench/Nature/Cover/Nature Cancer/5_10.png,groundtruth,5_10.txt,MAC_Bench/Nature/Cover/Nature Cancer/2_4.png,MAC_Bench/Nature/Cover/Nature Cancer/2_4.png,vith,2_4.txt,MAC_Bench/Nature/Cover/Nature Cancer/2_6.png,MAC_Bench/Nature/Cover/Nature Cancer/2_6.png,clip,2_6.txt,test
Bioconjugate Chemistry,2024_10,Which of the following options best describe the cover story?,"Engineering of the primary structural protein of gas vesicles, GvpA, with the tetracysteine tag enables its reaction with the fluorogenic molecule FlAsH and subsequent visualization of the assembled gas vesicle structures inside cells with fluorescence microscopy.",D,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_2.png,vitg,2013_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2017_1.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2017_1.png,clip,2017_1.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2022_11.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2022_11.png,ave_2,2022_11.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_10.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_10.png,groundtruth,2024_10.txt,test
Chem & Bio Engineering,2024_8,Which of the following options best describe the cover story?,"on photo and photothermal conversion of CO2 to CO and CH4 by single-atom catalysis are reviewed. The reaction mechanism is comprehensively analyzed, and future research directions are prospected.",B,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,ave_3,2024_4.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_8.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,ave_2,2024_6.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_7.png,clip,2024_7.txt,train
Cell Chemical Biology,31_10,Which of the following options best describe the cover story?,"On the cover: Two pathways (umbrellas) are responsible for NAD+ production in mammalian
cells: the NAPRT-mediated biosynthesis pathway and the NAMPT-mediated salvage pathway.
Zhu et al. develop and assess a second generation PROTAC (rain drops) that degrades and functionally
inactivates NAMPT, leading to the death of NAMPT-positive tumor cells exclusively
relying on the salvage pathway (right fire). In contrast, cells expressing NAPRT are
capable of using nicotinic acid to synthesize NAD+ and are resistant to the effects
of the NAMPT-targeting PROTAC (left fire).",D,MAC_Bench/Cell/Cover/Cell Chemical Biology/16_12.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/16_12.png,ave_3,16_12.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_9.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_9.png,clip,31_9.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_1.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_1.png,vitg,19_1.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_10.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_10.png,groundtruth,31_10.txt,train
Nature Reviews Earth & Environment,5_9,Which of the following options best describe the cover story?,"Grapes produced for winemaking are highly susceptible to change in climate, particularly extreme heat and drought. This Review examines the changing geography of existing and emerging winegrowing regions, and recommends adaptation measure to increasing heat and modified drought, pest and disease pressure.
Image credit: Bloomberg creative/Getty images. Cover design: Carl Conway.",B,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_5.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_5.png,clip,5_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_9.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_9.png,groundtruth,5_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_9.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_9.png,vith,2_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_12.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_12.png,vitg,5_12.txt,val
ACS Earth and Space Chemistry,2024_1,Which of the following options best describe the cover story?,of t-HC(S)SH,D,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_11.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_11.png,vitg,2024_11.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_3.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_3.png,clip,2024_3.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_2.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_2.png,vith,2022_2.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_1.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_1.png,groundtruth,2024_1.txt,train
Inorganic Chemistry,2025_4,Which of the following options best describe the cover story?,"The cover image illustrates that the incorporation of Fe ions (orange) into CuO-based materials (blue) holds great promise for enhancing oxygen-evolution reaction (OER) performance. Especially, this study using different methods and strategies reveals that Fe ions anchored to the CuO surface significantly enhance OER performance. These findings offer valuable insights into the role of Fe in CuO structures for advancing electrocatalysis efficiency.",A,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_4.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_47.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2024_47.png,clip,2024_47.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2018_17.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2018_17.png,vitg,2018_17.txt,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_22.png,MAC_Bench/ACS/Cover/Inorganic Chemistry/2023_22.png,vith,2023_22.txt,val
Nature Water,2_7,Which of the following options best describe the cover story?,"Freshwater snow with a touch of microplastic
From an ecosystem services point of view, microplastics can have both direct and indirect impacts on natural systems. The artwork on the cover depicts the interactions between microplastics and freshwater snow, illustrating their aggregation in water, a pivotal process shaping their respective settling rates. By unravelling these dynamics, it is possible to gain deeper insights into the fate of microplastics and their consequential impact on natural cycles.
See Parrella et al.
Image: Thomas Kast. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Water/1_4.png,MAC_Bench/Nature/Cover/Nature Water/1_4.png,ave_2,1_4.txt,MAC_Bench/Nature/Cover/Nature Water/2_7.png,MAC_Bench/Nature/Cover/Nature Water/2_7.png,groundtruth,2_7.txt,MAC_Bench/Nature/Cover/Nature Water/1_7.png,MAC_Bench/Nature/Cover/Nature Water/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Water/1_8.png,MAC_Bench/Nature/Cover/Nature Water/1_8.png,vitg,1_8.txt,val
Macromolecules,2024_8,Which of the following options best describe the cover story?,"Isotactic polybutene-1 possesses superior mechanical properties, but exhibits a peculiar amorphous phase dragged to a slow crystalline phase transition after melt processing. A surprising fast transition is observed in full deuterated polybutene-1, attributing to the much lower vibrational entropy in the D polymer, resulting in a much reduced energy barrier for the transition.",D,MAC_Bench/ACS/Cover/Macromolecules/2011_22.png,MAC_Bench/ACS/Cover/Macromolecules/2011_22.png,clip,2011_22.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_16.png,MAC_Bench/ACS/Cover/Macromolecules/2010_16.png,vith,2010_16.txt,MAC_Bench/ACS/Cover/Macromolecules/2018_23.png,MAC_Bench/ACS/Cover/Macromolecules/2018_23.png,vitg,2018_23.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_8.png,MAC_Bench/ACS/Cover/Macromolecules/2024_8.png,groundtruth,2024_8.txt,train
Nature Climate Change,14_3,Which of the following options best describe the cover story?,"Heating and cooling feedbacks of buildings
Buildings interact with their environment in many ways. For example, heat is released to the atmosphere when energy is used for cooling or heating, but this energy demand is also affected by the temperature around the buildings, creating feedbacks between the buildings and their environment. In this month's issue, Xinchang Li, Lei Zhao and colleagues show that when this two-way feedback between buildings and their environment is considered, the additional atmospheric warming through buildings is higher than previously thought.
See Li et al. and News & Views by González-Cruz
Image: shunli zhao / Moment / Getty Images. Cover design: Debbie Maizels",A,MAC_Bench/Nature/Cover/Nature Climate Change/14_3.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_3.png,groundtruth,14_3.txt,MAC_Bench/Nature/Cover/Nature Climate Change/9_5.png,MAC_Bench/Nature/Cover/Nature Climate Change/9_5.png,clip,9_5.txt,MAC_Bench/Nature/Cover/Nature Climate Change/14_5.png,MAC_Bench/Nature/Cover/Nature Climate Change/14_5.png,ave_2,14_5.txt,MAC_Bench/Nature/Cover/Nature Climate Change/11_7.png,MAC_Bench/Nature/Cover/Nature Climate Change/11_7.png,vitg,11_7.txt,train
ACS Applied Polymer Materials,2024_7,Which of the following options best describe the cover story?,"The cover art depicts an innovative solar reflector design. Utilizing polymer-based one-dimensional photonic crystals, the originally transparent polymer achieves near 100% solar reflectivity. This design shows considerable potential for diverse applications, including photovoltaics, smart agriculture, space missions, and wearable solar devices. Part of the cover art was created using MidJourney AI.",B,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_7.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_7.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_14.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_14.png,ave_3,2024_14.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_11.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_11.png,vitg,2023_11.txt,train
NATURE REVIEWS DRUG DISCOVERY,23_7,Which of the following options best describe the cover story?,"A framework for RNA-based medicines, inspired by the Review on p421.
Cover design: S. Harris",A,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_7.png,groundtruth,23_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_1.png,vith,19_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_8.png,vitg,23_8.txt,train
ACS Synthetic Biology,2024_9,Which of the following options best describe the cover story?,"The cover art for this issue of ACS Synthetic Biology is part of the ACS Diversity and Inclusion Cover Art Series. The image, titled ""Pipetting Hand,"" was created by Michael Rosnach,",D,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_10.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_10.png,clip,2024_10.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2014_7.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2014_7.png,vith,2014_7.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,ave_1,2025_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_9.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_9.png,groundtruth,2024_9.txt,test
ACS Applied Engineering Materials,2024_6,Which of the following options best describe the cover story?,"Detecting defects inside of microarchitected materials is important to ensure their intended functionality. The high scattering nature of these materials hides these defects, especially those deep inside these materials, from sight. In our manuscript we investigate defects deep inside these structures by using optical microscopy techniques with submicrometer resolution to resolve the entire structure and pinpoint the nature and location of individual defects. Art by the team of INMYWORK Studio.",A,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_8.png,vitg,2024_8.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_3.png,vith,2024_3.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_3.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_3.png,clip,2023_3.txt,train
Trends in Microbiology,32_1,Which of the following options best describe the cover story?,"Phages have evolved anti-defence systems (ADSs) to evade bacterial
defence mechanisms, forming complex antagonistic interactions with bacterial
defence systems. This cover image uses a chessboard as a visual metaphor for
how phage populations evolve layers of anti-defence strategies to evade bacterial
defence mechanisms. The floating elements next to the bacterial and phage pieces
symbolise “the moves” they can make to combat one and other – molecular
mechanisms they utilise. The cover illustrates some examples of those molecular
mechanisms (phage pieces and machinery are in grey, bacterial are in orange). For
instance, bacterial restriction-modification system (enzymes with cloud-like shape)
cleaves unmodified phage DNA, but phages evade the recognition by modifying
DNA; bacterial retron Ec78 cleaves endogenous tRNA-Tyr (yellow), preventing phage
protein translation, but phages overcome translation shutdown by encoding their
tRNA-Tyr, enabling their replication. In this issue, Murtazalieva and colleagues discuss
these and many other ADSs and their interplay with bacterial defence systems.
Image courtesy: Khalimat Murtazalieva, Aleksandra Petrovskaya, Abhishek Rawat,
Robert Finn.",A,MAC_Bench/Cell/Cover/Trends in Microbiology/32_1.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_1.png,groundtruth,32_1.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/22_13.png,MAC_Bench/Cell/Cover/Trends in Microbiology/22_13.png,vitg,22_13.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/27_2.png,MAC_Bench/Cell/Cover/Trends in Microbiology/27_2.png,vith,27_2.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_4.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_4.png,clip,32_4.txt,train
Cell Reports Methods,4_7,Which of the following options best describe the cover story?,"On the cover: In this issue, Kowalczewski et al. present a single-organoid analytics workflow that integrates micropatterning-based
organoid engineering and machine learning techniques to evaluate the impact of micropatterned
geometric designs on cardiac organoid properties. Cover image of a human cardiac organoid
is courtesy of Zhen Ma.",A,MAC_Bench/Cell/Cover/Cell Reports Methods/4_7.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_7.png,groundtruth,4_7.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_5.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_5.png,vith,4_5.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_11.png,vitg,3_11.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_9.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_9.png,clip,3_9.txt,train
Med,5_3,Which of the following options best describe the cover story?,"On the cover: Gastric cancer ranks as the fifth most prevalent cancer globally and
the fourth leading cause of cancer-related mortality. The prognosis for advanced gastric
cancer is poor, underscoring the urgent need for more effective treatment strategies.
In this issue of Med, Li et al. conducted a phase 2 clinical study to explore the efficacy and safety of combining
two different anti-HER2 antibodies plus XELOX as first-line therapy for patients with
HER2-positive advanced gastric cancer. The study reveals that the treatment regimen
significantly extended progression-free survival and improved antitumor response in
these patients, with manageable safety profiles, supporting the clinical benefits
of dual HER2 blockade.",D,MAC_Bench/Cell/Cover/Med/5_9.png,MAC_Bench/Cell/Cover/Med/5_9.png,clip,5_9.txt,MAC_Bench/Cell/Cover/Med/4_6.png,MAC_Bench/Cell/Cover/Med/4_6.png,vith,4_6.txt,MAC_Bench/Cell/Cover/Med/4_7.png,MAC_Bench/Cell/Cover/Med/4_7.png,vitg,4_7.txt,MAC_Bench/Cell/Cover/Med/5_3.png,MAC_Bench/Cell/Cover/Med/5_3.png,groundtruth,5_3.txt,train
ACS Applied Optical Materials,2025_1,Which of the following options best describe the cover story?,"Computer simulations highlight the potential of Cu3BiS3-based solar cells with optimized buffer layers and transparent conductive oxides, providing insights for the development of non-toxic, cost-effective, and high-performance photovoltaics.",D,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_1.png,ave_3,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,clip,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2025_1.png,groundtruth,2025_1.txt,val
Nature Biomedical Engineering,8_11,Which of the following options best describe the cover story?,"Stable transposon-driven integration of transgenes into immune cells
This issue highlights optimized base editors targeting the exon-7 mutation in SMN2 to restore the expression of the survival motor neuron protein to normal levels, the virus-mediated delivery of a transposon and an mRNA-encoded transposase for the integration of transgenes into immune cells, the enhanced viability of genome-engineered T cells transfected by electroporation via an isotonic buffer that dampens cytosolic cGAS–DNA interactions, the annotation of variants of the BRCA2 gene in human pluripotent stem cells, that host genes involved in viral processes can constrain the lentiviral delivery and expression of Cas13, and that replacing amino acid residues in an immunodominant and conserved T cell epitope in the capsid of an adeno-associated virus can abrogate its immunogenicity while preserving its function and potency.
The cover illustrates a gene-delivery system that enhances the stability of the integration of a desired transgene in immune cells by relying on a Sleeping Beauty transposase encoded into an mRNA delivered by an adeno-associated virus.
See Ye et al.
Image: Lupeng Ye and Sidi Chen. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_7.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_7.png,clip,8_7.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_11.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_11.png,groundtruth,8_11.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_11.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_11.png,vith,5_11.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,vitg,7_4.txt,train
Nature Mental Health,2_3,Which of the following options best describe the cover story?,"Earth, brain and health
Our October issue features a Comment announcing the Earth, Brain and Health Commission that has been convened with Nature Mental Health. By applying innovative cutting-edge technology, such as remote-sensing satellite data, with other sociodemographic and neuroimaging data, the commission seeks to shape new ways to identify biomarkers to help understand the environmental impact on mental health. Our cover is a nod to capturing the topography of green and blue spaces, as well as associations with brain and mental health, using satellite imagery.
Read more in the Comment from Schumann et al
Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,ave_2,2_6.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,groundtruth,2_3.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,vith,2_10.txt,test
Trends in Immunology,45_11,Which of the following options best describe the cover story?,"Aligned with the Spring season, the image symbolizes development and
metamorphosis (as seen for butterflies). In terms of T lymphocyte development, CD4+
T cells in the mammalian intestinal intraepithelium can undergo massive transcriptional
reprogramming, leading to their metamorphosis into phenotypically and functionally
distinct CD4+CD8αα+ T cells. On pages 288–302, Can Li, Dominic Lanasa, and Jung-
Hyun Park review recent findings on the molecular mechanisms and developmental
pathways of CD4+CD8αα+ T cells. Image created with Biorender.com.",B,MAC_Bench/Cell/Cover/Trends in Immunology/38_2.png,MAC_Bench/Cell/Cover/Trends in Immunology/38_2.png,vitg,38_2.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_11.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_11.png,groundtruth,45_11.txt,MAC_Bench/Cell/Cover/Trends in Immunology/39_13.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_13.png,vith,39_13.txt,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,clip,39_14.txt,train
ACS Applied Polymer Materials,2024_11,Which of the following options best describe the cover story?,smart transparent flexible film as a Ca2+ pump,A,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_11.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_13.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_13.png,vitg,2024_13.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2023_9.png,ave_1,2023_9.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_7.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_7.png,clip,2024_7.txt,train
NATURE MATERIALS,24_2,Which of the following options best describe the cover story?,"Electronically morphing microrobot
A kirigami metasheet microrobot shows electronically programmable shape morphing and movement.
See Liu et al.
Image: Zihe Liang and Qingkun Liu, Shanghai Jiao Tong University; Itai Cohen, Cornell University. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/24_2.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/24_2.png,groundtruth,24_2.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/24_1.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/24_1.png,clip,24_1.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/18_4.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/18_4.png,ave_3,18_4.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/7_6.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/7_6.png,ave_2,7_6.txt,train
Nature Catalysis,7_4,Which of the following options best describe the cover story?,"Dispersion control
In their work, L. Robert Baker and colleagues investigate the effects of molecular dispersion of a heterogenized cobalt phthalocyanine on the rate and product selectivity in electrocatalytic CO2 reduction.
See Zhu et al.
Image: Elad Gross and Hadar Shema, Hebrew University, Jerusalem. Cover design: Alex Whitworth.",B,MAC_Bench/Nature/Cover/Nature Catalysis/3_2.png,MAC_Bench/Nature/Cover/Nature Catalysis/3_2.png,vith,3_2.txt,MAC_Bench/Nature/Cover/Nature Catalysis/7_4.png,MAC_Bench/Nature/Cover/Nature Catalysis/7_4.png,groundtruth,7_4.txt,MAC_Bench/Nature/Cover/Nature Catalysis/5_11.png,MAC_Bench/Nature/Cover/Nature Catalysis/5_11.png,vitg,5_11.txt,MAC_Bench/Nature/Cover/Nature Catalysis/2_3.png,MAC_Bench/Nature/Cover/Nature Catalysis/2_3.png,clip,2_3.txt,test
Macromolecules,2024_16,Which of the following options best describe the cover story?,The cover illustrates the elastically active network in a Brownian dynamics simulation of associative polymers with an association density just above the gel point. A random color is assigned to each linear section connecting branch points in the network. The number of paths forming unique cycles in the network determines the elastic modulus of the gel.,A,MAC_Bench/ACS/Cover/Macromolecules/2024_16.png,MAC_Bench/ACS/Cover/Macromolecules/2024_16.png,groundtruth,2024_16.txt,MAC_Bench/ACS/Cover/Macromolecules/2015_4.png,MAC_Bench/ACS/Cover/Macromolecules/2015_4.png,clip,2015_4.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_14.png,MAC_Bench/ACS/Cover/Macromolecules/2022_14.png,vitg,2022_14.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_17.png,MAC_Bench/ACS/Cover/Macromolecules/2022_17.png,ave_1,2022_17.txt,test
ACS Sustainable Resource Management,2024_12,Which of the following options best describe the cover story?,Valorization of mining waste into sustainable building materials for heavy metals immobilization.  View the article.,A,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_10.png,clip,2024_10.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_2.png,ave_2,2024_2.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,vith,2024_8.txt,train
Joule,8_4,Which of the following options best describe the cover story?,"On the cover: In this issue, Wang et al. introduce a novel method to excavate kinetic reaction knowledge from limited battery
thermal experiments, transforming it into millions of data points for machine learning,
which in turn enables highly accurate and broadly generalizable predictions. In the
imagery, the chips symbolize the computational power of machine learning, while the
batteries and dispersing cubes represent the latent thermochemical knowledge that,
once excavated into large-scale training data, can liberate the scale and capability
of machine learning methods. Image credit: Yu Wang and Chaoyang Zhao.",C,MAC_Bench/Cell/Cover/Joule/1_1.png,MAC_Bench/Cell/Cover/Joule/1_1.png,clip,1_1.txt,MAC_Bench/Cell/Cover/Joule/8_7.png,MAC_Bench/Cell/Cover/Joule/8_7.png,vith,8_7.txt,MAC_Bench/Cell/Cover/Joule/8_4.png,MAC_Bench/Cell/Cover/Joule/8_4.png,groundtruth,8_4.txt,MAC_Bench/Cell/Cover/Joule/8_12.png,MAC_Bench/Cell/Cover/Joule/8_12.png,vitg,8_12.txt,train
Trends in Ecology & Evolution,39_11,Which of the following options best describe the cover story?,"Organisms can gain information about other individuals through
visual signals. These signals often involve patches of colour that are viewed against
a background that can be another part of the same animal or an environmental
background, both demonstrated by the chromodorid nudibranch depicted here. On
pages 188–198, Eleanor Caves and colleagues argue that how a colour signal is
perceived is highly dependent on its background. As such, to understand the function
and evolution of colour signals, the signal must be considered in conjunction with
the
background as a 'multicomponent' signal. Photo credit: Jordan Casey.",D,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/30_4.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/30_4.png,vith,30_4.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_12.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/34_12.png,vitg,34_12.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/24_7.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/24_7.png,clip,24_7.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_11.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_11.png,groundtruth,39_11.txt,test
Acta Pharmacologica Sinica,45_9,Which of the following options best describe the cover story?,"Cover Credit: Lonicerin (LCR), a bioactive compound found in plants of the Lonicera japonica species, exhibits anti-inflammatory and antioxidant activities. However, the effect of LCR on wound healing under diabetes and the specific mechanism of LCR's effect has not been covered. In this study, we discovered for the first time that LCR has a potent ability to promote cell autophagy and identified the upstream regulatory protein Sirt1 as a potential target for LCR. Additionally, our results indicate that LCR can promote angiogenesis, cell migration, and anti-apoptosis, which may have implications for other research areas such as skin flap survival, In this studycerebral ischemia and reperfusion, and intestinal epithelial injury healing. Doi:10.1038/s41401-023-01193-5. See the article in pages 815–830",D,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_11.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_11.png,vith,45_11.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_11.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_11.png,clip,44_11.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_7.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_7.png,vitg,41_7.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,groundtruth,45_9.txt,test
Structure,33_1,Which of the following options best describe the cover story?,"On the cover: Alternative complex III from Chloroflexus aurantiacus (CaACIII) is a multi-subunit quinol acceptor oxidoreductase that couples quinol oxidation
with transmembrane proton translocation in respiratory and photosynthetic electron
transport chains. This image shows CaACIII structures determined by X-ray crystallography
and cryoelectron microscopy. The CaACIII crystal structure presented in this issue
by Wu et al. highlights the conformational stability of its core functional modules and reveals
local flexibility in regions with low sequence conservation.",C,MAC_Bench/Cell/Cover/Structure/22_7.png,MAC_Bench/Cell/Cover/Structure/22_7.png,vith,22_7.txt,MAC_Bench/Cell/Cover/Structure/32_5.png,MAC_Bench/Cell/Cover/Structure/32_5.png,vitg,32_5.txt,MAC_Bench/Cell/Cover/Structure/33_1.png,MAC_Bench/Cell/Cover/Structure/33_1.png,groundtruth,33_1.txt,MAC_Bench/Cell/Cover/Structure/29_6.png,MAC_Bench/Cell/Cover/Structure/29_6.png,clip,29_6.txt,train
Trends in Pharmacological Sciences,45_9,Which of the following options best describe the cover story?,"The Frizzled family (FZD1-10) of transmembrane receptors belongs to the
class F of G protein-coupled receptors. FZDs bind to and are activated by Wingless/Int1
(WNT) proteins. The WNT/FZD signaling system regulates crucial aspects of developmental
biology and stem cell regulation. Dysregulation of WNT/FZD communication can lead
to
developmental defects and diseases such as cancer and fibrosis. In this issue, Schulte
et al. discuss the growing evidence that FZDs are not only druggable but also behave like
GPCRs with regard to ligand-induced dynamics and mechanisms of receptor-transducer
coupling, and the basis to target FZDs pharmacologically. The cover is a schematic
representation of the WNT/FZD signaling system. WNT (yellow), FZD (dark pink), the
LDL
receptor-related protein 5/6 (in cyan), Disheveled (in light blue), heterotrimeric
G proteins
(blue, light pink and light yellow). The small molecule (in pink) depicts the potential
to target
FZDs for therapeutic purposes particularly in cancer. Membrane lipids are shown in
white.
The cover was designed by Dr. Julien Bous with Blender 4.02.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,vitg,34_8.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/31_5.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/31_5.png,clip,31_5.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_9.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_9.png,groundtruth,45_9.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_12.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_12.png,vith,34_12.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_12,Which of the following options best describe the cover story?,"‘The power of antioxidants’, inspired by the Review on p13
Cover design: Vicky Summersby",A,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_12.png,groundtruth,25_12.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_3.png,vitg,22_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/16_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/16_1.png,vith,16_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_4.png,clip,23_4.txt,train
iScience,27_12,Which of the following options best describe the cover story?,"On the cover: A living thermometer with a rainbow of colors and deeper than a 10-story
building, the Grand Prismatic Hot Spring in Yellowstone National Park abodes with
thermophilic microbes, chlorophyll, carotenoids, soil, organics, and hydrothermal
water. This is nature's high-temperature, chromatic, organofunctionalized slurry.
Sarkar et al. show how viscoelastic properties in clay slurries alter when the clay is organomodified
with betaines. Image credit: Kausik Mukhopadhyay.",D,MAC_Bench/Cell/Cover/iScience/14_1.png,MAC_Bench/Cell/Cover/iScience/14_1.png,vith,14_1.txt,MAC_Bench/Cell/Cover/iScience/27_10.png,MAC_Bench/Cell/Cover/iScience/27_10.png,clip,27_10.txt,MAC_Bench/Cell/Cover/iScience/27_5.png,MAC_Bench/Cell/Cover/iScience/27_5.png,vitg,27_5.txt,MAC_Bench/Cell/Cover/iScience/27_12.png,MAC_Bench/Cell/Cover/iScience/27_12.png,groundtruth,27_12.txt,train
iScience,27_10,Which of the following options best describe the cover story?,"On the cover: The cover image, related to the article by Li et al., vividly depicts the unique microbial ecosystem during the Cambrian “explosion.”
Here, increased microbially induced erosion, particularly by boring cyanobacteria
Endoconchia, significantly influenced the shell calcification process, resulting in the evolution
of complex and densely packed tubule systems in shells of Nomgoliella, one of earliest mineralized mollusks recovered from western Mongolia. Image credit:
Xi Liu and Luoyang Li.",C,MAC_Bench/Cell/Cover/iScience/14_1.png,MAC_Bench/Cell/Cover/iScience/14_1.png,clip,14_1.txt,MAC_Bench/Cell/Cover/iScience/26_8.png,MAC_Bench/Cell/Cover/iScience/26_8.png,vitg,26_8.txt,MAC_Bench/Cell/Cover/iScience/27_10.png,MAC_Bench/Cell/Cover/iScience/27_10.png,groundtruth,27_10.txt,MAC_Bench/Cell/Cover/iScience/26_5.png,MAC_Bench/Cell/Cover/iScience/26_5.png,vith,26_5.txt,train
Trends in Endocrinology & Metabolism,35_7,Which of the following options best describe the cover story?,"From the need for better preclinical models of disease to the use of new
technologies that can recapitulate the complexity of living systems, our approach
in
studying metabolic diseases is constantly being refined. This month, we focus on the
issue of modeling metabolism: our authors reflect on novel methodological approaches
in the study of endocrine and metabolic disorders and provide new frameworks to
address some of the current questions in diabetes, obesity, liver disease, cancer
metabolism and host-microbiome homeostasis. Our cover depicts this variety of
perspectives as building blocks of different colors and sizes that together contribute
a more comprehensive model of metabolism. Artwork credit: modified from Jobalou/
Getty Images.",C,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_10.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_10.png,clip,30_10.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_4.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_4.png,vith,27_4.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_7.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_7.png,groundtruth,35_7.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/29_4.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/29_4.png,vitg,29_4.txt,train
Matter,7_6,Which of the following options best describe the cover story?,"On the cover: This month marks the 5-year anniversary of the publication of our first
issue of Matter, volume 1, issue 1 on July 3rd, 2019. Since our launch, each article has represented a small piece of materials
research, a kind of “building block” contributing to the overall progression of materials
science. This “building block” theme has been a motif across the years of Matter, reflected in our branding, and now commemorated by the cover, which depicts a celebratory
“five” among building blocks. The five colors (white, red, blue, green, and yellow)
are also no accident, representing both 5 years as well as five innovations our team
has brought to academic publishing (see this month’s editorial by Steve Cranford). Join us as we celebrate our anniversary!",A,MAC_Bench/Cell/Cover/Matter/7_6.png,MAC_Bench/Cell/Cover/Matter/7_6.png,groundtruth,7_6.txt,MAC_Bench/Cell/Cover/Matter/1_6.png,MAC_Bench/Cell/Cover/Matter/1_6.png,ave_2,1_6.txt,MAC_Bench/Cell/Cover/Matter/3_5.png,MAC_Bench/Cell/Cover/Matter/3_5.png,vitg,3_5.txt,MAC_Bench/Cell/Cover/Matter/7_1.png,MAC_Bench/Cell/Cover/Matter/7_1.png,clip,7_1.txt,train
Chemical Research in Toxicology,2024_3,Which of the following options best describe the cover story?,"Inhalation toxicity testing primarily relies on rodent testing, highlighting the lack of reliable and validated lung cell models. To enhance the predictive power of lung cell models, the adverse outcome pathway (AOP) framework can be applied. This framework causally links sequences of key events (KEs) from a molecular initiating event (MIE) to an adverse outcome in animals. We summarize the current state of art in endpoint analysis in the two systems with a focus on inflammatory-induced effects and provide some guidance for future research directions to improve the alignment.",B,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_2.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2012_2.png,vith,2012_2.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_3.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2021_4.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2021_4.png,clip,2021_4.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2016_10.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2016_10.png,vitg,2016_10.txt,val
Nature Reviews Earth & Environment,5_5,Which of the following options best describe the cover story?,"The future of the land carbon sink depends on the temperature response of ecosystem respiration. This Review explores observational and experimental evidence for a unimodal temperature response of respiration and the implications for carbon sequestration predictions.
Image credit: Amith Nag Photography/Getty images. Cover design: Carl Conway",A,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_5.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_5.png,groundtruth,5_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_8.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/3_8.png,clip,3_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/1_3.png,vitg,1_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_4.png,MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/2_4.png,vith,2_4.txt,train
Nature Sustainability,7_4,Which of the following options best describe the cover story?,"Sustainable microfabrication
Microfabrication has a crucial role in device fabrication but has an unfavourable environmental footprint. Yang and colleagues present a bioinspired permeable junction approach for sustainable microfabrication, using no hazardous chemicals and substantially reduced energy consumption.
See Yang et al.
Image: Bozhi Tian, University of Chicago. Cover design: Alex Whitworth",B,MAC_Bench/Nature/Cover/Nature Sustainability/6_12.png,MAC_Bench/Nature/Cover/Nature Sustainability/6_12.png,vith,6_12.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_4.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_4.png,groundtruth,7_4.txt,MAC_Bench/Nature/Cover/Nature Sustainability/7_5.png,MAC_Bench/Nature/Cover/Nature Sustainability/7_5.png,vitg,7_5.txt,MAC_Bench/Nature/Cover/Nature Sustainability/4_8.png,MAC_Bench/Nature/Cover/Nature Sustainability/4_8.png,clip,4_8.txt,train
Chem & Bio Engineering,2024_4,Which of the following options best describe the cover story?,"Cross-linked Phe–Phe-based peptide nanofibers can construct networks and thus form macroscopic supramolecular hydrogels. This work provides a summary of the construction strategies of Phe–Phe-based macroscopic supramolecular hydrogels and lists the represented biomedical applications. In addition, the perspectives and challenges of Phe–Phe-based macroscopic peptide hydrogels are presented.",B,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_6.png,vitg,2024_6.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_2.png,clip,2024_2.txt,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_5.png,MAC_Bench/ACS/Cover/Chem & Bio Engineering/2024_5.png,vith,2024_5.txt,test
ACS Food Science & Technology,2024_11,Which of the following options best describe the cover story?,"This illustration, created using the ""Image Creator from Playground AI"" tool, vividly represents the theme of our study. It features a cup of dark tea, with steam symbolizing warmth and health, alongside a healthy-looking white rat. The graphic contrasts this with an image of a lethargic white rat, representing the condition before dark tea consumption. Additionally, it includes a graph or infographic indicating improvements in glucose levels or other diabetic markers in white rats post-",B,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_11.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_2.png,vith,2022_2.txt,test
NATURE REVIEWS DRUG DISCOVERY,23_1,Which of the following options best describe the cover story?,"Targeting the TNF and TNFR superfamilies, inspired by the Review on p939.
Cover design: S. Harris",C,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_10.png,clip,22_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_1.png,groundtruth,23_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_12.png,vitg,21_12.txt,train
Cancer Cell,43_2,Which of the following options best describe the cover story?,"On the cover: The cover illustrates how glioblastoma (GBM) aligns its growth with
the brain's daily rhythms. Inspired by artist Sophie Taeuber-Arp and designed by Dr.
Olivia Walch, this visual highlights the daytime tumor growth driven by the circadian
surge in glucocorticoids (green dots). Gonzalez-Aponte et al. discover that blocking circadian regulation of glucocorticoid receptor signaling
slows GBM proliferation in both mouse and human GBM models. Targeting circadian mechanisms
to combat GBM holds great promise and has significant implications for understanding
how the circadian system may influence cancer progression, both within the brain and
beyond.",D,MAC_Bench/Cell/Cover/Cancer Cell/28_4.png,MAC_Bench/Cell/Cover/Cancer Cell/28_4.png,vith,28_4.txt,MAC_Bench/Cell/Cover/Cancer Cell/26_5.png,MAC_Bench/Cell/Cover/Cancer Cell/26_5.png,clip,26_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/33_2.png,MAC_Bench/Cell/Cover/Cancer Cell/33_2.png,ave_2,33_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/43_2.png,MAC_Bench/Cell/Cover/Cancer Cell/43_2.png,groundtruth,43_2.txt,train
Caner Cell,42_2,Which of the following options best describe the cover story?,"On the cover: In their review, Galluzzi and colleagues examine the mechanisms by which malignant cells evade immune elimination through
a novel “three Cs” framework. Camouflage refers to cancer cells’ ability to disguise themselves from the immune system,
preventing recognition as a threat. Coercion involves the direct or indirect inhibition of immune functions by neoplastic
cells, while cytoprotection describes the capacity of malignant cells to withstand cytotoxic agents.
Together, these strategies contribute to immunoevasion and resistance to (immuno)therapy
across various oncological contexts.",D,MAC_Bench/Cell/Cover/Caner Cell/23_2.png,MAC_Bench/Cell/Cover/Caner Cell/23_2.png,vith,23_2.txt,MAC_Bench/Cell/Cover/Caner Cell/40_3.png,MAC_Bench/Cell/Cover/Caner Cell/40_3.png,clip,40_3.txt,MAC_Bench/Cell/Cover/Caner Cell/20_1.png,MAC_Bench/Cell/Cover/Caner Cell/20_1.png,vitg,20_1.txt,MAC_Bench/Cell/Cover/Caner Cell/42_2.png,MAC_Bench/Cell/Cover/Caner Cell/42_2.png,groundtruth,42_2.txt,val
Nature Chemistry,16_1,Which of the following options best describe the cover story?,"Boosting CO2 conversion with Mo oxycarbides
Molybdenum carbides are promising heterogeneous catalysts for CO2 conversion chemistry, but they typically require harsh preparation conditions and suffer from poor stability. Now, Jiafeng Yu, Jian Sun and colleagues have shown that molybdenum oxide, produced by flame spray pyrolysis synthesis, is stable at 600 °C for 2,000 hours during the reverse water–gas shift reaction. Extensive characterization revealed the in situ formation of a cubic α-molybdenum carbide with unsaturated surface oxycarbides (depicted on the cover) that serve as active sites for CO2 conversion.
See Yu, Sun et al.
Image: Xingtao Sun, Jiafeng Yu, and Jian Sun, Dalian Institute of Chemical Physics, CAS. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/Nature Chemistry/1_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/1_6.png,clip,1_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_1.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_1.png,groundtruth,16_1.txt,MAC_Bench/Nature/Cover/Nature Chemistry/13_3.png,MAC_Bench/Nature/Cover/Nature Chemistry/13_3.png,vith,13_3.txt,MAC_Bench/Nature/Cover/Nature Chemistry/12_11.png,MAC_Bench/Nature/Cover/Nature Chemistry/12_11.png,vitg,12_11.txt,train
NATURE REVIEWS CANCER,24_6,Which of the following options best describe the cover story?,"Thriving in an inhospitable environment, inspired by the Review on p448.
Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_10.png,vitg,17_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/19_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/19_6.png,vith,19_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_2.png,clip,23_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_6.png,groundtruth,24_6.txt,train
Nature Metabolism,6_11,Which of the following options best describe the cover story?,"Insulin sparkles
Using a zinc-based fluorophore with spinning-disc confocal microscopy, Peng et al. visualize insulin secretion in intact mouse islets, thereby revealing a subpopulation of β cells that make a disproportionally large contribute to overall insulin release. Each coloured dot indicates an exocytosis event against the backdrop of stained β cells of a mouse islet.
See Peng et al.
Image: Liangyi Chen, Peking University. Cover Design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/Nature Metabolism/6_11.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_11.png,groundtruth,6_11.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_11.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_11.png,ave_3,3_11.txt,MAC_Bench/Nature/Cover/Nature Metabolism/1_6.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Metabolism/1_1.png,MAC_Bench/Nature/Cover/Nature Metabolism/1_1.png,clip,1_1.txt,test
Nature Chemical Biology,20_7,Which of the following options best describe the cover story?,"Lighting up proteins by RNA editing
A method termed RENAPT combines RNA editing and site-specific incorporation of non-canonical amino acids, enabling introduction of small chemical tags into endogenous proteins for live-cell imaging. The cover depicts a super-resolution image of the GRP94 protein, an endoplasmic reticulum-resident chaperone (in red), achieved through RENAPT.
See Hao et al. and Doura et al.
Image: Tao Liu and Min Hao, Peking University. Cover design: Alex Wing",A,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_7.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_7.png,groundtruth,20_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_1.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_1.png,clip,20_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_4.png,ave_1,17_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_2.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_2.png,vitg,13_2.txt,train
Cancer Cell,42_1,Which of the following options best describe the cover story?,"On the cover: Yang et al. reveal a mechanism of immune evasion of tumor-initiating cells (TICs) and suggest
the strategy of combining CD155 blockade with anti-PD-1/PD-L1 therapy. The cover image
shows a cuckoo chick in a host bird’s nest, symbolizing CD49f+ TICs within the tumor microenvironment. The host bird represents neutrophils, attracted
to the cuckoo through its mimicry of the host’s calls, similar to how TICs release
CXCL2 to recruit neutrophils. The host then invests resources to feed the cuckoo,
paralleling neutrophils secreting CCL4 to support TIC survival. As the cuckoo matures,
its feathers (representing CD155) help it blend in and evade predators like the snake,
which symbolizes CD8+ T cells.",A,MAC_Bench/Cell/Cover/Cancer Cell/42_1.png,MAC_Bench/Cell/Cover/Cancer Cell/42_1.png,groundtruth,42_1.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_2.png,MAC_Bench/Cell/Cover/Cancer Cell/42_2.png,vith,42_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/29_2.png,MAC_Bench/Cell/Cover/Cancer Cell/29_2.png,vitg,29_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/33_2.png,MAC_Bench/Cell/Cover/Cancer Cell/33_2.png,clip,33_2.txt,val
Cell Genomics,4_6,Which of the following options best describe the cover story?,"On the cover: Mycena olivaceomarginata, October 15, 2022, Torød, Vestfold, Norway. This species has the biggest mushroom
genome hitherto found, which is the epitome of the research by Bugge Harder et al. in this issue of Cell Genomics. Mycena species generally have very large genomes compared to most other mushrooms, but this
particular species has a genome that is 3–4 times the size of that of the already
large Mycena genomes. Photographer: Arne Aronsen.",B,MAC_Bench/Cell/Cover/Cell Genomics/4_4.png,MAC_Bench/Cell/Cover/Cell Genomics/4_4.png,vitg,4_4.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_6.png,MAC_Bench/Cell/Cover/Cell Genomics/4_6.png,groundtruth,4_6.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_9.png,MAC_Bench/Cell/Cover/Cell Genomics/3_9.png,ave_0,3_9.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_3.png,MAC_Bench/Cell/Cover/Cell Genomics/2_3.png,clip,2_3.txt,train
Biomacromolecules,2024_5,Which of the following options best describe the cover story?,"The misuse of antibiotics has already contributed to the emergence of multi-drug-resistant bacteria. To address antibiotic-resistance issues and explore the combination rules, synergic strategies involving AMP-mimetic antimicrobial polymers, including various combinations with commercially available antimicrobials, organic small molecule photosensitizers, inorganic nanomaterials, and nitric oxide, have been proposed.",C,MAC_Bench/ACS/Cover/Biomacromolecules/2022_5.png,MAC_Bench/ACS/Cover/Biomacromolecules/2022_5.png,ave_2,2022_5.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2019_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2019_10.png,ave_1,2019_10.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2024_5.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2020_4.png,MAC_Bench/ACS/Cover/Biomacromolecules/2020_4.png,clip,2020_4.txt,train
ACS Earth and Space Chemistry,2025_2,Which of the following options best describe the cover story?,"The stark and wild Tablelands of Newfoundland, Canada. The environmental conditions present at the Tablelands have produced minerals and materials similar to those found on Mars. The barren yet beautiful landscape is likewise potentially reflective of early Martian conditions.",D,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_4.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_4.png,ave_2,2024_4.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_1.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_1.png,clip,2022_1.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_1.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2025_2.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2025_2.png,groundtruth,2025_2.txt,train
Nature Microbiology,9_10,Which of the following options best describe the cover story?,"Vectors of the cadaver decomposition microbiome
Decomposing remains, whether human or other animal, are attractive to organisms across the tree of life because they are concentrated sources of nutrients and moisture. Blow flies (likely to be Chrysomya rufifacies in this photo), for which larval stages are obligate flesh feeders, are key vectors of a specialist carrion decomposer microbial network that appears universal across terrestrial environments.
See Burcham et al.
Credit: David O. Carter, Chaminade University of Honolulu. Cover design: Valentina Monaco.",C,MAC_Bench/Nature/Cover/Nature Microbiology/7_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/7_2.png,vitg,7_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/2_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/2_2.png,vith,2_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_10.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_10.png,groundtruth,9_10.txt,MAC_Bench/Nature/Cover/Nature Microbiology/1_1.png,MAC_Bench/Nature/Cover/Nature Microbiology/1_1.png,clip,1_1.txt,val
Developmental Cell,59_13,Which of the following options best describe the cover story?,"On the cover: Wiring cellular decision-making during trunk development. The image
shows a Trunk-Like Structures (TLS) used in this study in combination with a molecular
recorder to investigate progenitor cell dynamics during mouse gastrulation and early
organogenesis. TLS is depicted as a complex mixture of wires which reflect their underlying
cell types from fluorescent staining on top of a phylogenetic lineage tree with leaves
colored by different cell types, to symbolize the complex repertoire of differentiation
decisions that we characterized to ensure correct tissue morphogenesis. To learn more
about how the authors assess the features of axial elongation and trunk tissue morphogenesis
using TLSs, see Bolondi et al. Image credit: Adriano Bolondi.",C,MAC_Bench/Cell/Cover/Developmental Cell/32_1.png,MAC_Bench/Cell/Cover/Developmental Cell/32_1.png,vitg,32_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/51_2.png,MAC_Bench/Cell/Cover/Developmental Cell/51_2.png,clip,51_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_13.png,MAC_Bench/Cell/Cover/Developmental Cell/59_13.png,groundtruth,59_13.txt,MAC_Bench/Cell/Cover/Developmental Cell/27_6.png,MAC_Bench/Cell/Cover/Developmental Cell/27_6.png,vith,27_6.txt,val
ACS Omega,2025_4,Which of the following options best describe the cover story?,"The cover art illustrates Trypanosoma brucei navigating the bloodstream, highlighting the epigenetic target sirtuin-2-related protein 1, a key enzyme in DNA repair modulation. The figure spotlights its druggable binding site, interacting with molecular fragments that offer disruptive pathways for next-generation antiparasitic drug discovery. This artwork was created using OpenArt.ai.",D,MAC_Bench/ACS/Cover/ACS Omega/2021_8.png,MAC_Bench/ACS/Cover/ACS Omega/2021_8.png,clip,2021_8.txt,MAC_Bench/ACS/Cover/ACS Omega/2024_17.png,MAC_Bench/ACS/Cover/ACS Omega/2024_17.png,ave_2,2024_17.txt,MAC_Bench/ACS/Cover/ACS Omega/2021_10.png,MAC_Bench/ACS/Cover/ACS Omega/2021_10.png,ave_3,2021_10.txt,MAC_Bench/ACS/Cover/ACS Omega/2025_4.png,MAC_Bench/ACS/Cover/ACS Omega/2025_4.png,groundtruth,2025_4.txt,train
Science,387_6729,Which of the following options best describe the cover story?,"COVER Pollination in walnuts (such as this Persian walnut, Juglans regia) and pecans occurs through a genetically controlled temporal flowering dimorphism. Two distinct morphs alternate their phases of male and female flowering across the season, promoting outcrossing that has maintained a stable equilibrium throughout tens of millions of years of evolution. See eado5578.
Photo: Philippe Clement/NPL/Minden Pictures",A,MAC_Bench/Science/Cover/Science/387_6729.png,MAC_Bench/Science/Cover/Science/387_6729.png,groundtruth,387_6729.txt,MAC_Bench/Science/Cover/Science/344_6185.png,MAC_Bench/Science/Cover/Science/344_6185.png,vitg,344_6185.txt,MAC_Bench/Science/Cover/Science/324_5932.png,MAC_Bench/Science/Cover/Science/324_5932.png,clip,324_5932.txt,MAC_Bench/Science/Cover/Science/362_6412.png,MAC_Bench/Science/Cover/Science/362_6412.png,ave_2,362_6412.txt,val
Lab Animal,53_10,Which of the following options best describe the cover story?,"Reporting metadata in animal research
Data sharing allows data to be reused in other analyses, avoiding resources (and animals) being wasted in unnecessary replication studies. A new Perspective proposes a minimal metadata set to enable data sharing and repurposing in animal research, contributing to the principle of reduction.
See Moresis et al.
Cover image: Debbie Maizels. Cover design: Debbie Maizels.",B,MAC_Bench/Nature/Cover/Lab Animal/50_4.png,MAC_Bench/Nature/Cover/Lab Animal/50_4.png,clip,50_4.txt,MAC_Bench/Nature/Cover/Lab Animal/53_10.png,MAC_Bench/Nature/Cover/Lab Animal/53_10.png,groundtruth,53_10.txt,MAC_Bench/Nature/Cover/Lab Animal/53_8.png,MAC_Bench/Nature/Cover/Lab Animal/53_8.png,vitg,53_8.txt,MAC_Bench/Nature/Cover/Lab Animal/50_2.png,MAC_Bench/Nature/Cover/Lab Animal/50_2.png,vith,50_2.txt,train
Trends in Cognitive Sciences,28_7,Which of the following options best describe the cover story?,"In this issue of Trends in Cognitive Sciences, Shaun Gallagher and
colleagues propose a ‘pattern theory of compassion’ that clarifies distinctions between
empathy, sympathy, and compassion. The pattern theory identifies a set of diverse
components that form a dynamic Gestalt constitutive of compassion. A review of
neuroscientific studies of compassion provides evidence to support the pattern theory,
and the processes and factors that make up the pattern can contribute to guide
compassion training. The anthropomorphic cartoon on the cover depicts some of the
differences between empathy, sympathy, and compassion. From left to right: empathy
(quasi-isomorphic) is signified by the quasi-same color for empathizer-empathized;
sympathy (related but not isomorphic) is signified by similar band colors; compassion
(non-isomorphic) is signified by different colors. Image by Junio Aglioti Colombini.",D,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_6.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_6.png,ave_1,18_6.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_12.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_12.png,clip,20_12.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_7.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_7.png,vith,18_7.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_7.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_7.png,groundtruth,28_7.txt,test
Nature Synthesis,3_1,Which of the following options best describe the cover story?,"Layered nitride materials from metastable polymorphs
Stable nitride thin film materials with layered 2D-like crystal structures are synthesized from 3D metastable intermediates. The short-range order in these 3D disordered polymorphs has a low-energy transformation barrier to the stable layered 2D-like structure.
See Zakutayev et al.
Image: Alfred Hicks, National Renewable Energy Laboratory. Cover design: Thomas Phillips",D,MAC_Bench/Nature/Cover/Nature Synthesis/2_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_1.png,ave_2,2_1.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,vitg,2_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_3.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_3.png,clip,3_3.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,groundtruth,3_1.txt,train
Trendsin Neurosciences,48_2,Which of the following options best describe the cover story?,"The amygdala is a multi-nuclear limbic system structure that functions
as a primary processing center for social and emotional behaviors in the vertebrate
brain. The term ‘amygdala’ comes from the Greek word for ‘almond’ due to its
characteristic ovoid shape. In this issue of Trends in Neurosciences, Joshua Corbin
and colleagues review how one of the key nuclei of the amygdala, the medial
amygdala, is formed from embryonic development and how these developmental
programs may drive the emergences of innate social behaviors. The cover image
shows an almond tree at two stages of its lifecycle; during springtime when flowers
are blooming and during summer when it has reached its mature state. The arrows
in the young tree invoke the formation of different lineages of amygdala neurons
that form different branches of the tree, which then differentiate into populations
of neurons that control different aspects of medial amygdala regulated behaviors.
Cover image credits: Benjamin Toth/Getty Images; cover design by Joshua Corbin.",B,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/38_9.png,vith,38_9.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/48_2.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/48_2.png,groundtruth,48_2.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,clip,47_3.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/48_1.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/48_1.png,vitg,48_1.txt,train
Nature Reviews Chemistry,8_5,Which of the following options best describe the cover story?,"Electronic waste or e-waste is an ever-increasing problem driven by the global population’s insatiable thirst for the latest gadgets. Discarded electronics contain a range of valuable materials, which might be recovered and reused. Recycling e-waste can reduce carbon emissions and the release of hazardous materials into soil and water. Furthermore, the scarcity of some natural resources will begin to limit the new technologies that can be built if we do not begin to better understand how to recycle these waste streams. See Niu et al.
Image: Carl Conway; Cover design: Carl Conway",C,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_7.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_7.png,ave_2,8_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_11.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_11.png,ave_3,8_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_5.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_5.png,groundtruth,8_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_12.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_12.png,clip,7_12.txt,train
Nature Physics,20_10,Which of the following options best describe the cover story?,"Universal dynamics out of equilibrium
The dynamics of isolated quantum many-body systems far from equilibrium is a field of study that pertains to many situations, including ultracold atoms, quantum spin magnets, and quark–gluon matter. Here, magnetization measurements in a spinor atomic gas show a way to classify universal dynamics based on symmetry and topology.
See Huh et al. and Prüfer
Image: Jae-yoon Choi, KAIST and Koushik Mukherjee, Lund University. Cover Design: Amie Fernandez.",C,MAC_Bench/Nature/Cover/Nature Physics/15_6.png,MAC_Bench/Nature/Cover/Nature Physics/15_6.png,vith,15_6.txt,MAC_Bench/Nature/Cover/Nature Physics/15_4.png,MAC_Bench/Nature/Cover/Nature Physics/15_4.png,ave_1,15_4.txt,MAC_Bench/Nature/Cover/Nature Physics/20_10.png,MAC_Bench/Nature/Cover/Nature Physics/20_10.png,groundtruth,20_10.txt,MAC_Bench/Nature/Cover/Nature Physics/17_1.png,MAC_Bench/Nature/Cover/Nature Physics/17_1.png,clip,17_1.txt,train
Lab Animal,53_12,Which of the following options best describe the cover story?,"The PREMISE database of Macaca Fascicularis PET/MRI brain imaging
Nonhuman primate neuroimaging is a rapidly growing and extremely promising area of neuroscience research that suffers from a lack of data. Neuroimaging database sharing can accelerate research in this field, while limiting the number of animals used. A new Article presents The PREMISE database, a PET/MR dataset of Macaca Fascicularis brain images structured according to BIDS standards and available for researchers.
See Becker et al.
Cover image: Marina Spence. Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Lab Animal/49_7.png,MAC_Bench/Nature/Cover/Lab Animal/49_7.png,clip,49_7.txt,MAC_Bench/Nature/Cover/Lab Animal/48_3.png,MAC_Bench/Nature/Cover/Lab Animal/48_3.png,vith,48_3.txt,MAC_Bench/Nature/Cover/Lab Animal/53_12.png,MAC_Bench/Nature/Cover/Lab Animal/53_12.png,groundtruth,53_12.txt,MAC_Bench/Nature/Cover/Lab Animal/48_1.png,MAC_Bench/Nature/Cover/Lab Animal/48_1.png,vitg,48_1.txt,val
Nature Physics,20_11,Which of the following options best describe the cover story?,"Emergent higher orders
The dynamics of complex systems are often modelled using low-rank matrices, but the formal validity of this method has not yet been confirmed. Thibeault et al. present an analysis of random networks and real-world data that sheds light on this low-rank hypothesis and its implications.
See Thibeault et al. and Gao
Image: Myriam Thibeault and Vincent Thibeault, Université Laval. Cover Design: Amie Fernandez.",D,MAC_Bench/Nature/Cover/Nature Physics/20_7.png,MAC_Bench/Nature/Cover/Nature Physics/20_7.png,vitg,20_7.txt,MAC_Bench/Nature/Cover/Nature Physics/20_3.png,MAC_Bench/Nature/Cover/Nature Physics/20_3.png,ave_0,20_3.txt,MAC_Bench/Nature/Cover/Nature Physics/17_11.png,MAC_Bench/Nature/Cover/Nature Physics/17_11.png,clip,17_11.txt,MAC_Bench/Nature/Cover/Nature Physics/20_11.png,MAC_Bench/Nature/Cover/Nature Physics/20_11.png,groundtruth,20_11.txt,train
BDJ Student,31_2,Which of the following options best describe the cover story?,"Vol 31 | Issue 2
In this spring issue of BDJ Student, our lead feature takes a closer look at four dental professionals who have taken their clinical knowledge and applied it outside the practice
Cover illustration by Cat Sims",D,MAC_Bench/Nature/Cover/BDJ Student/30_1.png,MAC_Bench/Nature/Cover/BDJ Student/30_1.png,clip,30_1.txt,MAC_Bench/Nature/Cover/BDJ Student/29_2.png,MAC_Bench/Nature/Cover/BDJ Student/29_2.png,vitg,29_2.txt,MAC_Bench/Nature/Cover/BDJ Student/30_3.png,MAC_Bench/Nature/Cover/BDJ Student/30_3.png,ave_2,30_3.txt,MAC_Bench/Nature/Cover/BDJ Student/31_2.png,MAC_Bench/Nature/Cover/BDJ Student/31_2.png,groundtruth,31_2.txt,train
Nature Electronics,7_5,Which of the following options best describe the cover story?,"Tension builds
A 3D printing technique that relies on tension to pull metal ink from a nozzle can create free-standing metallic structures with high conductivities and aspect ratios. The photograph on the cover shows an electromagnetic bandgap metamaterial fabricated with the tension-driven 3D printing technique.
See Ling et al. and News & Views by Yang
Image: Tee Research Group, National University of Singapore. Cover design: Lauren Heslop.",A,MAC_Bench/Nature/Cover/Nature Electronics/7_5.png,MAC_Bench/Nature/Cover/Nature Electronics/7_5.png,groundtruth,7_5.txt,MAC_Bench/Nature/Cover/Nature Electronics/6_9.png,MAC_Bench/Nature/Cover/Nature Electronics/6_9.png,clip,6_9.txt,MAC_Bench/Nature/Cover/Nature Electronics/5_1.png,MAC_Bench/Nature/Cover/Nature Electronics/5_1.png,ave_0,5_1.txt,MAC_Bench/Nature/Cover/Nature Electronics/4_5.png,MAC_Bench/Nature/Cover/Nature Electronics/4_5.png,vitg,4_5.txt,train
Trends in Cognitive Sciences,28_1,Which of the following options best describe the cover story?,"Is a cognitive science of dreaming possible? In this issue of Trends in Cognitive
   Sciences, Remington Mallett and colleagues address the historical barriers and recent
advancements in dream research, focusing on the challenges of objective observation
and
the limitations of retrospective recall. The authors highlight innovative methodologies,
such as
content decoding and real-time reporting, that enhance our understanding of dream
content
and its neural correlates. They also examine the potential of dream engineering techniques
to manipulate dream experiences for therapeutic and experimental purposes. By promoting
interdisciplinary approaches, this work sets the stage for a new era in dream science.
Cover art by Carmen Mancuso.",C,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_1.png,clip,20_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/22_4.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/22_4.png,ave_2,22_4.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_1.png,groundtruth,28_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/22_3.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/22_3.png,ave_1,22_3.txt,train
Accounts of Chemical Research,2024_17,Which of the following options best describe the cover story?,"Buckminster Fuller's innovative concept, face-rotating polyhedra (FRP), involves individual faces rotating around central axes, creating distinctive facial patterns while preserving the polyhedral core. Drawing from this mathematical inspiration, our group has constructed numerous chiral molecular cages resembling the FRP structure, utilizing building blocks that showcase C/A and P/M rotational patterns.",D,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_12.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_12.png,vith,2014_12.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2011_10.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2011_10.png,clip,2011_10.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_5.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_5.png,vitg,2012_5.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,groundtruth,2024_17.txt,val
Cell Metabolism,36_9,Which of the following options best describe the cover story?,"On the cover: “Variability is the law of life, and as no two faces are the same, so
no two bodies are alike.”—Sir William Osler, 1903. Noone and Mucinski et al. outline the numerous factors contributing to individual response variation to exercise.
As the foundation of individual differences, intrinsic in sync with extrinsic factors
strongly impact health and response to exercise or treatment programs. Ultimately,
these factors must be synergistically considered for effective personalized preventative
medicine and greatest health outcomes. Image credit: Julia Saxton (julia.saxton@adventhealth.com).",C,MAC_Bench/Cell/Cover/Cell Metabolism/24_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/24_5.png,vith,24_5.txt,MAC_Bench/Cell/Cover/Cell Metabolism/17_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/17_5.png,ave_2,17_5.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_9.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_9.png,groundtruth,36_9.txt,MAC_Bench/Cell/Cover/Cell Metabolism/22_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/22_3.png,clip,22_3.txt,val
Molecular Pharmaceutics,2024_6,Which of the following options best describe the cover story?,"Point-of-care (POC) manufacturing facilities enable an agile pharmaceutical production paradigm that can respond to localized needs, providing personalized and precision medicine. We employed a theoretical framework encompassing the production of active pharmaceutical ingredient ""inks"" at a centralized facility, which are distributed to POC sites for DoD dispensing into/onto delivery vehicles (e.g., orodispersible films, capsules, and single liquid dose vials).",B,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_1.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_1.png,vith,2024_1.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_6.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_3.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_3.png,clip,2022_3.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2023_8.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2023_8.png,vitg,2023_8.txt,test
ACS Central Science,2024_1,Which of the following options best describe the cover story?,"as part of the journal's Diversity and Inclusion Cover Art Series. The piece represents the global and collaborative effort toward solving one of humanity’s most pressing issues: water scarcity. Each hand in the artwork represents a diverse scientist—reflecting the contributions of chemists from different geographic regions, racial backgrounds, and scientific expertise working together to fight against the same challenge using chemistry as a tool.",C,MAC_Bench/ACS/Cover/ACS Central Science/2023_7.png,MAC_Bench/ACS/Cover/ACS Central Science/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_6.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_1.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_3.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_3.png,ave_3,2024_3.txt,train
Trends in Genetics,40_7,Which of the following options best describe the cover story?,"The neuronal composition that makes up our brains is relatively stable
from shortly after birth to adulthood. However, these post-mitotic neurons continue
to
undergo property changes throughout the lifespan. In this issue, Gabrielle Prince,
Molly
Reynolds, Verdion Martina, and HaoSheng Sun describe recent characterizations of the
functional and molecular changes that neurons undergo across postnatal development
and discuss cell-intrinsic versus cell-extrinsic mechanisms in the regulation of neuronal
maturation. Illustration by Dalton Patterson, Sharrell Greene, and Gabrielle Prince.",B,MAC_Bench/Cell/Cover/Trends in Genetics/33_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/33_1.png,vith,33_1.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_7.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_7.png,groundtruth,40_7.txt,MAC_Bench/Cell/Cover/Trends in Genetics/37_9.png,MAC_Bench/Cell/Cover/Trends in Genetics/37_9.png,vitg,37_9.txt,MAC_Bench/Cell/Cover/Trends in Genetics/34_13.png,MAC_Bench/Cell/Cover/Trends in Genetics/34_13.png,clip,34_13.txt,test
Trends in Cancer,10_10,Which of the following options best describe the cover story?,"Many therapeutic strategies that are positive in preclinical mice
experiments fail in human clinical trials due to biological differences between mice
and humans. In this issue, Joshi et al. propose using pigs as alternative animals for
preclinical testing due to their many similarities shared with humans. In particular,
the
Oncopig model is likely to play a key role in developing novel cancer therapeutics.
Cover image courtesy of gettyimages/Danielle D. Hughson.",C,MAC_Bench/Cell/Cover/Trends in Cancer/4_11.png,MAC_Bench/Cell/Cover/Trends in Cancer/4_11.png,clip,4_11.txt,MAC_Bench/Cell/Cover/Trends in Cancer/1_2.png,MAC_Bench/Cell/Cover/Trends in Cancer/1_2.png,vith,1_2.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_10.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_10.png,groundtruth,10_10.txt,MAC_Bench/Cell/Cover/Trends in Cancer/8_1.png,MAC_Bench/Cell/Cover/Trends in Cancer/8_1.png,ave_3,8_1.txt,train
Nature Plants,10_4,Which of the following options best describe the cover story?,"Single-cell sequencing in seeds
Seed germination is controlled by the dynamic modulation of gene expression. Single-cell RNA sequencing can identify the gene regulatory networks that are specific to different cell types and states. In the image, different false colours indicate nuclei with distinct gene expression profiles in a germinating seed.
See Liew, L.C. et al.
Image: Lucas Auroux & Lim Chee Liew, La Trobe University, Australia. Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/Nature Plants/8_13.png,MAC_Bench/Nature/Cover/Nature Plants/8_13.png,vith,8_13.txt,MAC_Bench/Nature/Cover/Nature Plants/10_4.png,MAC_Bench/Nature/Cover/Nature Plants/10_4.png,groundtruth,10_4.txt,MAC_Bench/Nature/Cover/Nature Plants/4_5.png,MAC_Bench/Nature/Cover/Nature Plants/4_5.png,clip,4_5.txt,MAC_Bench/Nature/Cover/Nature Plants/10_12.png,MAC_Bench/Nature/Cover/Nature Plants/10_12.png,vitg,10_12.txt,test
ACS Photonics,2024_7,Which of the following options best describe the cover story?,. The image portrays light incident on the particle–surface system being funneled into polaritons supported by the surface. This effect is experimentally demonstrated by Abdullah et al. through the observation of enhanced light-to-surface coupling assisted by gold disks placed at an optimum distance from a gold surface. The strategy provides a solution to the long-standing problem of light–polariton coupling in nanophotonics.,B,MAC_Bench/ACS/Cover/ACS Photonics/2016_6.png,MAC_Bench/ACS/Cover/ACS Photonics/2016_6.png,vith,2016_6.txt,MAC_Bench/ACS/Cover/ACS Photonics/2024_7.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Photonics/2017_10.png,MAC_Bench/ACS/Cover/ACS Photonics/2017_10.png,vitg,2017_10.txt,MAC_Bench/ACS/Cover/ACS Photonics/2020_6.png,MAC_Bench/ACS/Cover/ACS Photonics/2020_6.png,clip,2020_6.txt,train
ACS Chemical Neuroscience,2024_18,Which of the following options best describe the cover story?,"Illustrative representation of the brain in which intense neurotransmitter excitations occur, represented by colored discharges. This cover art is intended to highlight our metabolomic and lipidomic study of GCPII-deficient mouse models, where it is the disruption of NAAG concentrations that affects the brain lipidome and metabolome. The cover art was generated using DALL·E 3.",C,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_7.png,ave_2,2021_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_14.png,ave_1,2024_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_18.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_18.png,groundtruth,2024_18.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,clip,2020_6.txt,val
Nature Reviews Chemistry,8_1,Which of the following options best describe the cover story?,"By mimicking the structure of cells, single- or multi-compartmented molecular nanoreactors have been developed. In their shells and pores of tuneable dimensions, catalytic sites can be embedded, making such nanoreactors a customisable material with applications in fields as diverse as phase separation, heterogeneous catalysis, energy storage, and bioengineering. For a discussion on the chemistry behind such nanoreactors, see Ma et al.
Image: Dongyuan Zhao; Cover design: Carl Conway",A,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_1.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_1.png,groundtruth,8_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_11.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/6_11.png,vith,6_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_2.png,clip,7_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/3_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/3_2.png,vitg,3_2.txt,val
Nature Chemical Engineering,1_11,Which of the following options best describe the cover story?,"Connecting the dots
The fast construction and on-the-fly reconfiguration of liquid-based devices have long been challenging. Now, Gu, Du and colleagues have developed a strategy to generate diverse liquid-based devices that can be designed and reconfigured on-demand within minutes simply by adding, connecting and removing liquid droplets in a pillared substrate. The cover shows a fluidic channel constructed using this method.
See Zeng et al. and Wang & Wang
Image: Yi Zeng, Southeast University. Cover Design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_11.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_11.png,groundtruth,1_11.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_6.png,vitg,1_6.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_1.png,vith,1_1.txt,train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_7,Which of the following options best describe the cover story?,"Pride in gastroenterology and hepatology, inspired by the Review on p377.
Cover design: Laura Marshall",C,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_4.png,clip,18_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_1.png,vith,19_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_7.png,groundtruth,21_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_6.png,vitg,18_6.txt,train
JACS Au,2025_2,Which of the following options best describe the cover story?,"The same, but different? Acyl hydrolases and acyl transferases in polyketide synthases possess the same fold. One catalyzes the hydrolysis of acyl groups, the other transfers malonyl groups to carrier proteins. The first structure of an acyl hydrolase is reported, providing insights into the catalytic mechanism, substrate tolerance, and the carrier protein interface.",D,MAC_Bench/ACS/Cover/JACS Au/2022_7.png,MAC_Bench/ACS/Cover/JACS Au/2022_7.png,vith,2022_7.txt,MAC_Bench/ACS/Cover/JACS Au/2025_1.png,MAC_Bench/ACS/Cover/JACS Au/2025_1.png,vitg,2025_1.txt,MAC_Bench/ACS/Cover/JACS Au/2022_10.png,MAC_Bench/ACS/Cover/JACS Au/2022_10.png,clip,2022_10.txt,MAC_Bench/ACS/Cover/JACS Au/2025_2.png,MAC_Bench/ACS/Cover/JACS Au/2025_2.png,groundtruth,2025_2.txt,train
BDJ In Practice,37_5,Which of the following options best describe the cover story?,"In this issue...
Welcome to the second equality, diversity and inclusion themed issue of BDJ In Practice.

Society is changing. Are we more tolerant and accepting than ever before, or have we gone the other way? In this issue we dive into dentistry and all things EDI
Cover illustration by Tim Marrs",C,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,vitg,35_8.txt,MAC_Bench/Nature/Cover/BDJ In Practice/35_9.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_9.png,ave_2,35_9.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_5.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_5.png,groundtruth,37_5.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,clip,36_1.txt,train
Industrial & Engineering Chemistry Research,2024_43,Which of the following options best describe the cover story?,"Phenolation is introduced as a simple yet very efficient modification strategy to improve the reactivity of hydrolysis lignin, resulting in better-defined bioaromatic fractions that are suitable for the",C,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_48.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_48.png,ave_2,2024_48.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_43.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_43.png,vith,2021_43.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_43.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_43.png,groundtruth,2024_43.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_13.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_13.png,clip,2022_13.txt,val
ACS Applied Nano Materials,2025_3,Which of the following options best describe the cover story?,Make excellent clean energy catalysts by combining colorful non-precious metals with MOF materials to protect our green water and mountains.,A,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_3.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_14.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_14.png,vitg,2023_14.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2024_4.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2018_10.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2018_10.png,vith,2018_10.txt,train
Nature Physics,20_12,Which of the following options best describe the cover story?,"Coherent control in chaotic cavities
Non-Hermitian physics enables dynamic control of optical behaviour in real time, such as reflectionless scattering modes, which have now been demonstrated in a chaotic photonic microcavity.
See Jiang et al. and Stone
Image: Xuefeng Jiang, Shixiong Yin and Andrea Alù, Photonics Initiative, Advanced Science Research Center, City University of New York. Cover Design: Amie Fernandez",C,MAC_Bench/Nature/Cover/Nature Physics/18_8.png,MAC_Bench/Nature/Cover/Nature Physics/18_8.png,vith,18_8.txt,MAC_Bench/Nature/Cover/Nature Physics/19_9.png,MAC_Bench/Nature/Cover/Nature Physics/19_9.png,vitg,19_9.txt,MAC_Bench/Nature/Cover/Nature Physics/20_12.png,MAC_Bench/Nature/Cover/Nature Physics/20_12.png,groundtruth,20_12.txt,MAC_Bench/Nature/Cover/Nature Physics/17_6.png,MAC_Bench/Nature/Cover/Nature Physics/17_6.png,clip,17_6.txt,val
Trends in Microbiology,32_3,Which of the following options best describe the cover story?,"Pathogenic Cryptococcus species are frequently isolated from diverse
environments worldwide. These human opportunistic pathogens are often associated
with bird excreta and plant material. Given the complexity of the Cryptococcus ecology,
in this issue, Magnus Hallas-Møller and colleagues have explored data from diverse
and
interrelated disciplines to better define natural hosts and growth sites of this fungus.
Especially given their lack of enzymatic machinery to degrade cellulose, Cryptococcus
species appear to be benign commensals on or in plants. However, the enhancement of
Cryptococcus mating by plant-derived material and their frequent environmental isolation
from vegetation argue for complex, inter-kingdom interactions between plants and these
human fungal pathogens. The cover art shows Cryptococcus neoformans on a Eucalyptus
leaf. The fungal cells (pink) nestle among waxy elongated epidermal cells (purple)
directly
on a vascular bundle close to guard cells (yellow) and basal epidermal cells (green).
Image courtesy: Helle Jakobe Martens, CloseUpImaging, Copenhagen.",B,MAC_Bench/Cell/Cover/Trends in Microbiology/23_4.png,MAC_Bench/Cell/Cover/Trends in Microbiology/23_4.png,clip,23_4.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_3.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_3.png,groundtruth,32_3.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/21_6.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_6.png,vitg,21_6.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/21_9.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_9.png,vith,21_9.txt,val
The Journal of Physical Chemistry B,2025_8,Which of the following options best describe the cover story?,Illustration of the importance of substitution at the C(9) position of doubly locked GFP chromophore derivatives to modulate two-photon absorption efficiency. View the article.,A,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_8.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_8.png,groundtruth,2025_8.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_13.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_13.png,vith,2023_13.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_23.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_23.png,clip,2021_23.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_2.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_2.png,vitg,2022_2.txt,train
Trends in Endocrinology & Metabolism,36_1,Which of the following options best describe the cover story?,"Gut-brain crosstalk regulates energy homeostasis through multiple
mechanisms. This month, we approach this relationship from a variety of perspectives,
including the neuroendocrine regulation of gut-brain signaling in metabolic disorders
(Gruber et al), the interaction between gut microbiome and circadian rhythms (Soliz-
Rueda et al), the microbial metabolites associated with gut health (Grant et al, Nunzi
et al) and the potential of microbiome-based therapies for metabolic diseases (Vazquez-
Uribe et al). The cover depicts gut-brain communication as sand in an hourglass,
highlighting its circadian component. Cover credits: Cristina Cuesta Martí.",B,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_9.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_9.png,clip,33_9.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/36_1.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/36_1.png,groundtruth,36_1.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/28_5.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/28_5.png,vith,28_5.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_9.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_9.png,vitg,27_9.txt,train
ACS Physical Chemistry Au,2024_6,Which of the following options best describe the cover story?,"Amino acids will be observed remotely, the diffuse interstellar bands will be linked to molecular carriers, and direct spectral observations of exoplanetary atmospheres will produce clear chemical signals.",C,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2023_3.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2023_3.png,ave_3,2023_3.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_4.png,vitg,2024_4.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_6.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2023_6.png,clip,2023_6.txt,val
Cell Chemical Biology,31_3,Which of the following options best describe the cover story?,"On the cover: Tang et al. uncover the interaction site and binding determinants for engagement of the IP3 receptor
(IP3R) by the alpha-helical BH4 domain of BCL-w. BCL-w BH4 targeting of IP3R modulates
calcium flux and protects neuronal axons from chemotherapy-induced degeneration. Lead
stapled BCL-w BH4 peptides are shown as shielding axons from the incoming threat,
thereby preventing peripheral neuropathy. Image credit: Eric Smith.",D,MAC_Bench/Cell/Cover/Cell Chemical Biology/26_1.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/26_1.png,clip,26_1.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_1.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/19_1.png,vitg,19_1.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_11.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_11.png,vith,31_11.txt,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_3.png,MAC_Bench/Cell/Cover/Cell Chemical Biology/31_3.png,groundtruth,31_3.txt,train
Nature Human Behaviour,8_11,Which of the following options best describe the cover story?,"3D shape perception
Recent research has shown that people can perceive the shape of objects, even when the objects are not directly perceptible (for instance, when draped in cloth). These findings present a challenge to existing theories of shape perception, which are based on the use of surface cues alone. Yildirim et al. present a computational model of three-dimensional shape perception that integrates intuitive physics and analysis-by-synthesis to explain how shape can be inferred both when surface object cues are available and when they are not (as in cloth draping).
See Yildirim et al.
Cover image: Lan Zhang/E+/Getty. Cover design: Bethany Vukomanovic.",B,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_10.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_10.png,vitg,5_10.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_11.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_11.png,groundtruth,8_11.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,clip,4_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_4.png,ave_2,5_4.txt,val
Journal of Medicinal Chemistry,2024_7,Which of the following options best describe the cover story?,"A novel aryl-piperazine derivative II-13 (MT-1207) is a potent α1 and 5-HT2A receptor antagonist that can achieve effective blood pressure reduction without damaging renal function and avoidance of the postural hypotension side effect. Currently, compound II-13, as a novel multitarget antihypertensive agent, is in phase II clinical trials in China. View the article.",C,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_22.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_22.png,ave_1,2022_22.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,clip,2010_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_7.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2019_3.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2019_3.png,ave_2,2019_3.txt,train
ACS Materials Letters,2024_3,Which of the following options best describe the cover story?,This work introduces a biohybrid system for in situ synthesis of CdS by Shewanella putrefaciens under photo-assisted enhancement for the purification of uranium mine wastewater. This study deepens the understanding of electron transfer pathways and physiological metabolic activities in a biohybrid system and provides an important reference for the purification of uranium mine wastewater.,C,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_3.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2019_3.png,vitg,2019_3.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_1.png,clip,2024_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_3.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_3.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_3.png,ave_2,2023_3.txt,train
Nature Chemical Biology,20_11,Which of the following options best describe the cover story?,"Peaks and valleys of GPCR signaling
The spatial organization of GPCRs is closely associated with their signaling responses and cellular function. Kockelkoren et al. reveal that the spatial organization is energetic coupling of receptors to the curvature of the plasma membrane. The image depicts the landscape of GPCR distribution at the plasma membrane of living cells.
See Kockelkoren et al.
Image credit: Gabriele Kockelkoren and Jens Carstensen, University of Copenhagen. Cover design: Alex Wing",A,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_11.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_11.png,groundtruth,20_11.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_10.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_10.png,clip,20_10.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_1.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_1.png,vitg,17_1.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_9.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/13_9.png,vith,13_9.txt,val
Cell Stem Cell,31_1,Which of the following options best describe the cover story?,"On the cover: In this issue, Shen and Zaballa et al. report on using Yamanaka factors (YF) for partial reprogramming in the mouse brain.
During development, YF induction results in increased neural proliferation, cortex
expansion, and improved behavior. Similar induction at adult stages improves neuron
plasticity and prevents the development of several Alzheimer’s disease hallmarks.
The cover image depicts a white, leafless winter tree that represents the aging neuron.
A segment of a branch, drawn in green with pink flowers, symbolizes the effects of
partial reprogramming in the brain, suggesting new neuron growth and rejuvenation.
Cover composed by Julia Kuhl.",D,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_4.png,vitg,6_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_3.png,vith,31_3.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/25_5.png,MAC_Bench/Cell/Cover/Cell Stem Cell/25_5.png,clip,25_5.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_1.png,groundtruth,31_1.txt,train
BDJ In Practice,37_1,Which of the following options best describe the cover story?,"In this issue...
In this final issue of 2024, our cover feature delves into one of the most important topics for any practitioner to consider: safeguarding and dental neglect in children",A,MAC_Bench/Nature/Cover/BDJ In Practice/37_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_1.png,groundtruth,37_1.txt,MAC_Bench/Nature/Cover/BDJ In Practice/34_12.png,MAC_Bench/Nature/Cover/BDJ In Practice/34_12.png,vitg,34_12.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_10.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_10.png,clip,36_10.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,vith,37_2.txt,train
Crystal Growth & Design,2024_1,Which of the following options best describe the cover story?,The dyeing of uric acid crystals by heteroatom-substituted rhodamines has revealed their robust and specific interactions. Sensitively tracking the stained uric acid crystals during their interaction with the living cells offers extensive information about their pathological processes.,A,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_2.png,vitg,2022_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_7.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_7.png,vith,2016_7.txt,train
Caner Cell,42_5,Which of the following options best describe the cover story?,"On the cover: Sun et al. characterize the mechanistic significance and diagnostic potential of plasma and
fecal metabolites in colorectal cancer (CRC). The cover artwork depicts the journey
of sailboats, symbolizing CRC progression. The dolphins (representing inhibitory metabolites
like allocholic acid) swim alongside a boat veering away from a storm, while sharks
(representing promoting metabolites like oleic acid) follow a boat heading into the
storm. A buoy at the diverging paths signifies early tumor diagnosis based on metabolite
analysis. Image credit: Jun Yu.",D,MAC_Bench/Cell/Cover/Caner Cell/33_1.png,MAC_Bench/Cell/Cover/Caner Cell/33_1.png,vitg,33_1.txt,MAC_Bench/Cell/Cover/Caner Cell/35_3.png,MAC_Bench/Cell/Cover/Caner Cell/35_3.png,vith,35_3.txt,MAC_Bench/Cell/Cover/Caner Cell/40_3.png,MAC_Bench/Cell/Cover/Caner Cell/40_3.png,clip,40_3.txt,MAC_Bench/Cell/Cover/Caner Cell/42_5.png,MAC_Bench/Cell/Cover/Caner Cell/42_5.png,groundtruth,42_5.txt,train
NATURE IMMUNOLOGY,25_10,Which of the following options best describe the cover story?,"Women in Neuroimmunology
March is Women’s History Month. This month’s issue celebrates the contributions of female neuroimmunologists.
For more information, see the Women in Immunology Collection
Image: nobeastsofierce Science / Alamy Stock Photo & Kiyoshi Takahase Segundo / Alamy Stock Photo. Cover design: Amie Fernandez",B,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_5.png,vith,22_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_10.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_10.png,groundtruth,25_10.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/4_6.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/4_6.png,clip,4_6.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/21_10.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/21_10.png,ave_2,21_10.txt,train
Nature Machine Intelligence,6_7,Which of the following options best describe the cover story?,"Self-motion estimation with neuromorphic resonator networks
Estimating position and movement relative to objects with vision is a challenging computational problem in robotics. Renner et al. propose a neuromorphic solution, aiming at low-power, brain-inspired machine vision for mobile robots. In this approach, event-based neuromorphic vision sensors convert luminance changes during movement into spikes, illustrated in the cover image, with colour representing time. A neural architecture then analyses scene structure and the sensor’s pose, building a working memory of the environment.
See Renner et al. and Renner et al.
Image: Alpha Renner and Lazar Supic. Cover design: Amie Fernandez",D,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_2.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_2.png,clip,6_2.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_6.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_6.png,vitg,6_6.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_5.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/2_5.png,vith,2_5.txt,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_7.png,MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_7.png,groundtruth,6_7.txt,train
Science Signaling,2007_393,Which of the following options best describe the cover story?,"COVER This week features a Perspective on regulation of vesicle release by a voltage-gated potassium channel. The image depicts interaction of the Kv2.1 channel with the vesicle fusion machinery. [Image: Christopher Bickel, AAAS]",A,MAC_Bench/Science/Cover/Science Signaling/2007_393.png,MAC_Bench/Science/Cover/Science Signaling/2007_393.png,groundtruth,2007_393.txt,MAC_Bench/Science/Cover/Science Signaling/3_136.png,MAC_Bench/Science/Cover/Science Signaling/3_136.png,vith,3_136.txt,MAC_Bench/Science/Cover/Science Signaling/8_402.png,MAC_Bench/Science/Cover/Science Signaling/8_402.png,clip,8_402.txt,MAC_Bench/Science/Cover/Science Signaling/2_65.png,MAC_Bench/Science/Cover/Science Signaling/2_65.png,vitg,2_65.txt,train
BDJ,237_9,Which of the following options best describe the cover story?,"In this issue
This issue features articles on teething, diabetes mellitus, and NHS patient dental charges.

Cover image: From 2011. By the end of the first decade of this century, the financial crisis of 2008 and the clearly accelerating move towards digital communications coalesced as we sat down to decide on the cover series for the first half of 2011. The surge away from physical mail to email was a trigger for us to select postage stamps as a cover series. We were helped hugely in this by Stuart Geddes. The one featured centrally on the cover of this issue was originally used on Volume 210 Issue 3 (12 February 2011) and here is a representative of the series as well as our sense of how electronic media were posed to, and have indeed become the dominant feature of, our present world.
©Tim Marrs, incorporating stamps originally provided by Stuart Geddes",D,MAC_Bench/Nature/Cover/BDJ/233_11.png,MAC_Bench/Nature/Cover/BDJ/233_11.png,vitg,233_11.txt,MAC_Bench/Nature/Cover/BDJ/233_12.png,MAC_Bench/Nature/Cover/BDJ/233_12.png,clip,233_12.txt,MAC_Bench/Nature/Cover/BDJ/237_5.png,MAC_Bench/Nature/Cover/BDJ/237_5.png,vith,237_5.txt,MAC_Bench/Nature/Cover/BDJ/237_9.png,MAC_Bench/Nature/Cover/BDJ/237_9.png,groundtruth,237_9.txt,train
Acta Pharmacologica Sinica,45_6,Which of the following options best describe the cover story?,"Cover Credit: Suppressive tumor immune microenvironment (TIME) contributes to tumor progression and immunotherapy failure. Noninvasive radiofrequency radiation (RFR) exposure reshapes TIME into an antitumor phenotype by altering the transcription profile of tumor-infiltrating immune cells in pulmonary metastatic melanoma, resulting in enhanced cytotoxicity signature of tumor-infiltrating CD8+ T and NK cell subsets. Doi:10.1038/s41401-024-01260-5. See the article in pages 1492–1505",C,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_6.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/41_6.png,vith,41_6.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_2.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/44_2.png,clip,44_2.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_6.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_6.png,groundtruth,45_6.txt,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_9.png,vitg,45_9.txt,train
Industrial & Engineering Chemistry Research,2024_15,Which of the following options best describe the cover story?,"This cover art illustrates the molecular-level H2S scavenging process, assisted by water, using simple aldehydes and glyoxal. Effective H2S removal is crucial to the oil and gas industry due to its environmental hazards, occupational health risks and potential damage to industrial facilities. Cover art created using StockCake.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_15.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_15.png,vitg,2023_15.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_15.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_15.png,groundtruth,2024_15.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_35.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_35.png,vith,2022_35.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_9.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_9.png,clip,2022_9.txt,train
Trends in Genetics,40_1,Which of the following options best describe the cover story?,"Starships are giant transposons found in fungi that mobilize genes as cargo
both within and between fungal genomes. In this issue, Andrew Urquhart, Aaron Vogan
and Emile Gluck-Thaler argue that Starships provide an unprecedented opportunity to
understand the genetic bases of fungal adaptation. Illustration by Oen Gregory.",B,MAC_Bench/Cell/Cover/Trends in Genetics/38_5.png,MAC_Bench/Cell/Cover/Trends in Genetics/38_5.png,vith,38_5.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_1.png,groundtruth,40_1.txt,MAC_Bench/Cell/Cover/Trends in Genetics/34_12.png,MAC_Bench/Cell/Cover/Trends in Genetics/34_12.png,vitg,34_12.txt,MAC_Bench/Cell/Cover/Trends in Genetics/36_1.png,MAC_Bench/Cell/Cover/Trends in Genetics/36_1.png,clip,36_1.txt,train
Immunity,57_2,Which of the following options best describe the cover story?,"On the cover: Innate immune memory is a phenomenon whereby past inflammatory responses
lead to establishment of epigenetic memory that affects secondary immune responses.
In this issue, Lercher et al. demonstrate that past SARS-CoV-2 (SARS2) infection facilitates antiviral innate immune
memory in alveolar macrophages (AMs), which is necessary and sufficient to ameliorate
disease caused by the unrelated respiratory virus influenza A virus (IAV). This is
illustrated by initial infection with SARS2 (top left; teal virus), leading to epigenetic
remodeling of naive AMs (purple) and formation of memory AMs (teal) that are better
equipped to limit disease caused by secondary IAV (bottom right; pink virus). Image
credit: Jessica Johnson.",D,MAC_Bench/Cell/Cover/Immunity/33_4.png,MAC_Bench/Cell/Cover/Immunity/33_4.png,clip,33_4.txt,MAC_Bench/Cell/Cover/Immunity/33_2.png,MAC_Bench/Cell/Cover/Immunity/33_2.png,vith,33_2.txt,MAC_Bench/Cell/Cover/Immunity/42_6.png,MAC_Bench/Cell/Cover/Immunity/42_6.png,ave_0,42_6.txt,MAC_Bench/Cell/Cover/Immunity/57_2.png,MAC_Bench/Cell/Cover/Immunity/57_2.png,groundtruth,57_2.txt,train
Nature Cities,1_4,Which of the following options best describe the cover story?,"Changing activities during urban growth
Cities change as they develop, but urban science often focuses on the recent past. This study uses a database of activities in Paris from 1829–1907 to understand how different activities, from food stores to passing fads, evolve as an iconic city grows.
See Gravier & Barthelemy
Image: Universal History Archive/Contributor/Getty. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Cities/2_1.png,MAC_Bench/Nature/Cover/Nature Cities/2_1.png,ave_2,2_1.txt,MAC_Bench/Nature/Cover/Nature Cities/1_4.png,MAC_Bench/Nature/Cover/Nature Cities/1_4.png,groundtruth,1_4.txt,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,MAC_Bench/Nature/Cover/Nature Cities/1_3.png,clip,1_3.txt,MAC_Bench/Nature/Cover/Nature Cities/1_8.png,MAC_Bench/Nature/Cover/Nature Cities/1_8.png,ave_3,1_8.txt,test
Nature Reviews Chemistry,8_3,Which of the following options best describe the cover story?,"How life arose on Earth starting from simple chemicals remains an open question — one to which we may never have a definitive answer. A shift from simple building blocks to systems that display the essential characteristics of life — confinement, metabolism, and replication — would have been necessary, ultimately coming together in conditions that are far-from-equilibrium. For a discussion of this transition, see Singh et al.
Image: Dibyendu Das; Cover design: Susanne Harris",C,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_4.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_4.png,vith,1_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/5_7.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/5_7.png,vitg,5_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_3.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_3.png,groundtruth,8_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/4_12.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/4_12.png,clip,4_12.txt,test
Nature Cell Biology,26_10,Which of the following options best describe the cover story?,"ER-phagy during neurogenesis
Quantitative proteomics analyses show the importance of selective autophagy in endoplasmic reticulum (ER) remodelling across neuronal subcompartments and decode the substrate selectivity of ER-phagy receptors during in vitro neurogenesis.
See Hoyer et al. and News & Views by Molinari
Image: Cristina Capitanio, Max Planck Institute of Biochemistry, Martinsried, Germany. Cover Design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Cell Biology/9_3.png,MAC_Bench/Nature/Cover/Nature Cell Biology/9_3.png,vitg,9_3.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/25_11.png,MAC_Bench/Nature/Cover/Nature Cell Biology/25_11.png,clip,25_11.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/26_10.png,MAC_Bench/Nature/Cover/Nature Cell Biology/26_10.png,groundtruth,26_10.txt,MAC_Bench/Nature/Cover/Nature Cell Biology/18_5.png,MAC_Bench/Nature/Cover/Nature Cell Biology/18_5.png,vith,18_5.txt,train
Nature Water,3_1,Which of the following options best describe the cover story?,"An all-water mission
Water observing and monitoring, both ground-based and space-based, are essential for understanding the water cycle and managing water resources. A recently launched space observatory, called the Surface Water and Ocean Topography (SWOT) satellite provides direct, high-resolution measurements of water elevation and volume across various water bodies, including open and coastal oceans (shown as coloured sea surface height anomalies), as well as lakes and rivers (displayed as water surface elevations), making it a truly comprehensive surface water mission. The image shows a snapshot of Earth’s surface water elevation from the SWOT satellite mission during its inaugural science orbit. Fully validated data is now publicly available for scientists to study changing water and energy cycles and for users to manage water resources worldwide.
See Vinogradova et al.
Image: NASA. Cover design: Laoise Mac Gabhann",B,MAC_Bench/Nature/Cover/Nature Water/1_10.png,MAC_Bench/Nature/Cover/Nature Water/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Water/3_1.png,MAC_Bench/Nature/Cover/Nature Water/3_1.png,groundtruth,3_1.txt,MAC_Bench/Nature/Cover/Nature Water/1_2.png,MAC_Bench/Nature/Cover/Nature Water/1_2.png,vitg,1_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_11.png,MAC_Bench/Nature/Cover/Nature Water/2_11.png,vith,2_11.txt,train
Trends in Ecology & Evolution,39_10,Which of the following options best describe the cover story?,"Atoll islands, such as Teti'aroa, French Polynesia, pictured here,
are often perceived as inevitably lost due to rising sea levels. On pages 258–266,
Sebastian Steibl and colleagues argue for protecting and restoring the processes of
atoll island accretion. Local conservation actions, along with reductions in greenhouse
gas emissions, are key to unlocking nature-based opportunities for enhancing atoll
resilience to global change. Photo credit: Tetiaroa Society info@tetiaroasociety.org.",D,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/28_7.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/28_7.png,vith,28_7.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/27_4.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/27_4.png,clip,27_4.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/26_1.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/26_1.png,vitg,26_1.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_10.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_10.png,groundtruth,39_10.txt,train
Trends in Endocrinology & Metabolism,35_5,Which of the following options best describe the cover story?,"Metabolic dysfunction-associated steatotic liver disease (MASLD) is the
most widespread global chronic liver disease. This month, Miao et al. (pp. 697–707)
discuss the hepatic and extrahepatic health outcomes of MASLD, its epidemiology
and economic burden on healthcare systems, calling for new public health strategies
to reduce the impact of this condition. On the cover, the steatotic liver, shackled
above the earth, symbolizes the heavy global burden of MASLD. Its scars and nodules
indicate the disease progression to steatohepatitis, liver fibrosis, or even cirrhosis.
The
red alert serves as a reminder to focus on this urgent issue and calls for attention
from
the whole world. Cover credit: concept design from Ming-Hua Zheng and Lei Miao;
illustration/colourisation from Peng Zhang.",A,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_5.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_5.png,groundtruth,35_5.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_10.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_10.png,ave_3,33_10.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/32_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/32_6.png,clip,32_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_2.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/33_2.png,ave_2,33_2.txt,train
Med,6_1,Which of the following options best describe the cover story?,"On the cover: Immunotherapy has revolutionized the standards of care for individuals
with cancer, yet not all patients obtain long-lasting benefit from these therapies.
This month, we feature a special issue covering the latest developments in cancer
immunotherapeutics, ranging from cell-based therapies to vaccines and tumor-targeting
bacteria. Through a series of Q&As, reviews and opinion pieces, we seek to highlight
some existing challenges in this field as well as potential breakthroughs that may
improve efficacy and deliver on the clinical promise of immunotherapy. Cover image:
Isaac Lane Koval/Corbis/VCG via Getty Images.",A,MAC_Bench/Cell/Cover/Med/6_1.png,MAC_Bench/Cell/Cover/Med/6_1.png,groundtruth,6_1.txt,MAC_Bench/Cell/Cover/Med/4_6.png,MAC_Bench/Cell/Cover/Med/4_6.png,ave_1,4_6.txt,MAC_Bench/Cell/Cover/Med/5_9.png,MAC_Bench/Cell/Cover/Med/5_9.png,clip,5_9.txt,MAC_Bench/Cell/Cover/Med/4_7.png,MAC_Bench/Cell/Cover/Med/4_7.png,vitg,4_7.txt,train
ACS Omega,2025_3,Which of the following options best describe the cover story?,", electrochemical deposition: A case study is conducted targeting glyme-based room-temperature aluminum (Al) electroplating solutions. The correlation found in this study will be used as a screening index to achieve higher plating speed.",C,MAC_Bench/ACS/Cover/ACS Omega/2021_11.png,MAC_Bench/ACS/Cover/ACS Omega/2021_11.png,ave_1,2021_11.txt,MAC_Bench/ACS/Cover/ACS Omega/2021_28.png,MAC_Bench/ACS/Cover/ACS Omega/2021_28.png,vitg,2021_28.txt,MAC_Bench/ACS/Cover/ACS Omega/2025_3.png,MAC_Bench/ACS/Cover/ACS Omega/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/ACS Omega/2020_31.png,MAC_Bench/ACS/Cover/ACS Omega/2020_31.png,clip,2020_31.txt,train
Nature Water,2_11,Which of the following options best describe the cover story?,"Open evapotranspiration data support water management
Annual evapotranspiration rates computed from OpenET for irrigated agricultural lands and wetland areas near the confluence of the Columbia and Snake rivers contrast with evapotranspiration from the surrounding shrubland and grassland ecosystems. OpenET uses satellite imagery and gridded meteorological data to provide publicly accessible evapotranspiration information to support data-driven water management. In this issue, the OpenET Consortium answers the question ‘how accurate is OpenET’ with model intercomparison and accuracy assessment of field-scale (30 m) evapotranspiration data from six satellite-driven models.
See Volk et al.
IMAGE: openetdata.org. COVER DESIGN: Valentina Monaco",C,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,ave_2,2_1.txt,MAC_Bench/Nature/Cover/Nature Water/1_2.png,MAC_Bench/Nature/Cover/Nature Water/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_11.png,MAC_Bench/Nature/Cover/Nature Water/2_11.png,groundtruth,2_11.txt,MAC_Bench/Nature/Cover/Nature Water/3_1.png,MAC_Bench/Nature/Cover/Nature Water/3_1.png,ave_3,3_1.txt,test
Environment & Health,2024_8,Which of the following options best describe the cover story?,"The propensities and health implications of coronavirus adhering onto and releasing from representative indoor contact surfaces, including plastic, glass, stainless steel, and wood, in simulated human body fluids are studied using quartz crystal microbalance.",C,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,ave_2,2023_1.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,clip,2024_9.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_8.png,MAC_Bench/ACS/Cover/Environment & Health/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Environment & Health/2025_1.png,MAC_Bench/ACS/Cover/Environment & Health/2025_1.png,vitg,2025_1.txt,train
Trends in Plant Science,29_7,Which of the following options best describe the cover story?,"Dioecious plant species exhibit sexual dimorphism in various aspects,
including morphology, physiology, life history, and behavior, potentially influencing
sex-specific interactions, but the mechanisms underlying belowground facilitation
in intersexual combinations remain less understood. Chunyang Li and colleagues
explore these mechanisms, which encompass resource complementarity, mycorrhizal
fungal networks, root exudate-mediated belowground chemical communication, as
well as plant–soil feedback. The authors propose that the achieved comprehensive
understanding of the potential positive consequences of sex-specific interactions
can
contribute to maintaining ecological equilibrium, conserving biodiversity, and enhancing
the productivity of agroforestry. The image shows symbols for complementary and
interdependent forces (Yin and Yang concept), such as male and female poplar trees
(dioecious plants), and man and women playing different yet complementary roles in
life.
Image credit: Zhichao Xia.",D,MAC_Bench/Cell/Cover/Trends in Plant Science/21_8.png,MAC_Bench/Cell/Cover/Trends in Plant Science/21_8.png,clip,21_8.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/28_10.png,MAC_Bench/Cell/Cover/Trends in Plant Science/28_10.png,vith,28_10.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/25_5.png,MAC_Bench/Cell/Cover/Trends in Plant Science/25_5.png,ave_1,25_5.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/29_7.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_7.png,groundtruth,29_7.txt,train
Nature Computational Science,4_9,Which of the following options best describe the cover story?,"Predicting the impact of wildfires
In recent years, the frequency and intensity of wildfires have increased due to the effects of climate change. To date, many established wildfire policies have been ineffective, and alternative approaches are therefore needed in order to reduce the damage caused by such wildfire events. In this issue, Hussam Mahmoud suggests that future wildfire models should take inspiration from epidemic network modeling to predict the damage to individual buildings, as well as to improve our understanding of the impact of different mitigation strategies on the community as a whole.
See Mahmoud
Image: Nitat Termmee / Moment / Getty Images. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Computational Science/4_12.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_12.png,ave_2,4_12.txt,MAC_Bench/Nature/Cover/Nature Computational Science/1_11.png,MAC_Bench/Nature/Cover/Nature Computational Science/1_11.png,clip,1_11.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_9.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_9.png,groundtruth,4_9.txt,MAC_Bench/Nature/Cover/Nature Computational Science/2_5.png,MAC_Bench/Nature/Cover/Nature Computational Science/2_5.png,ave_3,2_5.txt,train
Joule,8_9,Which of the following options best describe the cover story?,"On the cover: In this issue, Wang et al. introduce a multifunctional cross-linkable elastomer into perovskite films, revolutionizing
the development of highly efficient and mechanically resilient flexible perovskite
solar cells (f-PSCs). The zwitterionic fusion within the cross-linked elastomers,
residing on grain boundaries, endows the flexible perovskite films with an instantaneous
self-curing ability under mild treatment conditions. This proposed method is expected
to promote the progress of f-PSCs toward industrialization. Designed by Yaohua Wang.",C,MAC_Bench/Cell/Cover/Joule/2_10.png,MAC_Bench/Cell/Cover/Joule/2_10.png,clip,2_10.txt,MAC_Bench/Cell/Cover/Joule/8_7.png,MAC_Bench/Cell/Cover/Joule/8_7.png,vith,8_7.txt,MAC_Bench/Cell/Cover/Joule/8_9.png,MAC_Bench/Cell/Cover/Joule/8_9.png,groundtruth,8_9.txt,MAC_Bench/Cell/Cover/Joule/6_12.png,MAC_Bench/Cell/Cover/Joule/6_12.png,vitg,6_12.txt,train
ACS Infectious Diseases,2024_7,Which of the following options best describe the cover story?,The cover shows how integrating the 12 Green Chemistry principles into the pharmaceutical,B,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_9.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_9.png,vith,2018_9.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_8.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_8.png,clip,2018_8.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2017_11.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2017_11.png,vitg,2017_11.txt,train
Nature Reviews Cardiology,21_2,Which of the following options best describe the cover story?,"Atheroimmunology, inspired by the Review on p743
Cover design: Vicky Summersby",C,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,vitg,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_9.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_9.png,clip,19_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_2.png,groundtruth,21_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/19_7.png,vith,19_7.txt,val
Nature Human Behaviour,8_12,Which of the following options best describe the cover story?,"Conceptual bootstrapping
How does the mind bootstrap its way to complex concepts? Across four experiments, Zhao et al. show that a key feature of the acquisition of complex concepts is the incremental construction of compositional representations. The authors then develop a model of conceptual bootstrapping, which captures the process of learning complex concepts by recursively combining simpler concepts.
See Zhao et al.
Cover image: Bowen Xiong, Visual Artist. Cover design: Bethany Vukomanovic.",D,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_4.png,vith,6_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/2_5.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_9.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_9.png,vitg,5_9.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_12.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_12.png,groundtruth,8_12.txt,train
Matter,7_12,Which of the following options best describe the cover story?,"On the cover: Wearable kinesthetic technology is pivotal for the emerging human-metaverse
interface. The cover depicts a fully embedded textile tactile sensor array that provides
accurate and real-time haptic feedback. With assistance from machine learning, it
can discern roughness and identify shapes, offering vast potential as a metaverse
platform for communication, entertainment, and healthcare. See the related research
article by Jun Chen and colleagues to learn more.",D,MAC_Bench/Cell/Cover/Matter/2_2.png,MAC_Bench/Cell/Cover/Matter/2_2.png,ave_2,2_2.txt,MAC_Bench/Cell/Cover/Matter/5_3.png,MAC_Bench/Cell/Cover/Matter/5_3.png,vitg,5_3.txt,MAC_Bench/Cell/Cover/Matter/2_3.png,MAC_Bench/Cell/Cover/Matter/2_3.png,clip,2_3.txt,MAC_Bench/Cell/Cover/Matter/7_12.png,MAC_Bench/Cell/Cover/Matter/7_12.png,groundtruth,7_12.txt,train
Nature Reviews Endocrinology,20_9,Which of the following options best describe the cover story?,"How to manage iatrogenic adrenal insufficiency, inspired by the Review on p209.
Cover design: Jennie Vallis",C,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/9_3.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/9_3.png,vitg,9_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/9_1.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/9_1.png,ave_1,9_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_9.png,groundtruth,20_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_7.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_7.png,clip,18_7.txt,train
ACS Materials Letters,2025_2,Which of the following options best describe the cover story?,"This study introduces an efficient boric acid cross-linking strategy for enhancing the room-temperature phosphorescence (RTP) of PVA-doped films. The rigidity of the polymer matrix is increased through covalent cross-linking, resulting in both high efficiency and long lifetime by suppressing non-radiative decay and reducing luminescence quenching under ambient conditions. This RTP system has been successfully applied in inkjet printing and binary anti-counterfeiting applications.",D,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2022_1.png,clip,2022_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_6.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_6.png,vith,2024_6.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_3.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_3.png,vitg,2024_3.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2025_2.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2025_2.png,groundtruth,2025_2.txt,train
NATURE METHODS,21_10,Which of the following options best describe the cover story?,"Brighter autonomous bioluminescence
Autonomously glowing Arabidopsis thaliana plants express an improved version of the fungal bioluminescence pathway.
See Shakhova et al.
Image: Tatiana Karataeva, Planta LLC. Cover Design: Thomas Phillips.",D,MAC_Bench/Nature/Cover/NATURE METHODS/19_2.png,MAC_Bench/Nature/Cover/NATURE METHODS/19_2.png,clip,19_2.txt,MAC_Bench/Nature/Cover/NATURE METHODS/17_10.png,MAC_Bench/Nature/Cover/NATURE METHODS/17_10.png,ave_3,17_10.txt,MAC_Bench/Nature/Cover/NATURE METHODS/7_6.png,MAC_Bench/Nature/Cover/NATURE METHODS/7_6.png,vitg,7_6.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_10.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_10.png,groundtruth,21_10.txt,train
NATURE REVIEWS MOLECULAR CELL BIOLOGY,26_2,Which of the following options best describe the cover story?,"‘Understanding cell fate decisions’, inspired by the Review on p11
Cover design: Vicky Summersby",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_7.png,vith,21_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_8.png,vitg,23_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/14_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/14_4.png,clip,14_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_2.png,groundtruth,26_2.txt,val
ACS Applied Optical Materials,2024_11,Which of the following options best describe the cover story?,"Vanadium dioxide nanocomposite smart window films for building applications exhibit remarkable thermochromic properties, allowing automatic blockage and transmission of infrared radiation based on temperature changes. This semiconductor-to-metal transition authorizes efficient building technology, effectively reducing energy consumption associated with heating and cooling costs and subsequently minimizing carbon dioxide emissions.",B,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2025_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2025_1.png,vitg,2025_1.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_11.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_7.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_9.png,vith,2023_9.txt,train
ACS Materials Letters,2024_1,Which of the following options best describe the cover story?,The screening of most suitable dual atom alloy catalysts for the electrochemical CO2 reduction reaction to C1 and C2 products is accelerated implementing integrated density functional theory and machine learning methods.,C,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_5.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_8.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2023_8.png,vith,2023_8.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_1.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_4.png,MAC_Bench/ACS/Cover/ACS Materials Letters/2024_4.png,clip,2024_4.txt,test
Macromolecules,2024_9,Which of the following options best describe the cover story?,"This image illustrates the formation of a uniform film containing a high density of π-stacked helical poly(quinoline-2,3-diylmethylene) with cysteine derivatives at the chain ends on a Au substrate.",A,MAC_Bench/ACS/Cover/Macromolecules/2024_9.png,MAC_Bench/ACS/Cover/Macromolecules/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Macromolecules/2011_12.png,MAC_Bench/ACS/Cover/Macromolecules/2011_12.png,vith,2011_12.txt,MAC_Bench/ACS/Cover/Macromolecules/2021_18.png,MAC_Bench/ACS/Cover/Macromolecules/2021_18.png,vitg,2021_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2020_23.png,MAC_Bench/ACS/Cover/Macromolecules/2020_23.png,clip,2020_23.txt,train
Chemical Research in Toxicology,2024_11,Which of the following options best describe the cover story?,"Breast cancer mostly occurs in the upper quadrants of the breast, which is shown in the top left depiction of the breast. A huge number of changes result in neoplasms, which is depicted by the breast on the left (nonhomogenous breast tissue with numerous inconsistencies in the tissue). Changes in cancer proteomes, lipidomes, and metabolomes with respect to normal tissues, as well as chemotherapy-induced changes, are characterized in tumors with mass spectrometry. Samples derived from a tumor specimen are processed and applied for the separation of biological components by liquid chromatography and then subjected to a mass spectrometer for analysis. Identi",B,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/1998_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/1998_8.png,clip,1998_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_11.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2009_12.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2009_12.png,ave_1,2009_12.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_9.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2017_9.png,vith,2017_9.txt,train
NATURE MATERIALS,23_3,Which of the following options best describe the cover story?,"Phase engineering of 2D materials
A strategy of on-device phase engineering of two-dimensional materials is proposed, allowing the in situ realization of various lattice phases with distinct stoichiometries and versatile functions.
See Liu et al.
Image: Chaoyang Zhao, independent artist, and Junjie Shan, Nanjing University. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_3.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_3.png,groundtruth,23_3.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_8.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_8.png,vitg,20_8.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/7_5.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/7_5.png,clip,7_5.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/17_5.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/17_5.png,vith,17_5.txt,train
Molecular Pharmaceutics,2024_12,Which of the following options best describe the cover story?,"Molecular dynamics simulations unveil cisplatin delivery by carbon nanohorns (CNHs) in breast cancer cells. CNH cellular intake was kinetically sluggish; however, it might enhance the retention effect, improving the bioavailability of cisplatin in the tumor cells.",D,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,vith,2020_4.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_6.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_6.png,clip,2021_6.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_2.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_2.png,vitg,2020_2.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_12.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_12.png,groundtruth,2024_12.txt,train
Science,387_6734,Which of the following options best describe the cover story?,"COVER Climate change in the polar regions of our warming world is threatening to transform many of its features, such as this icy tableau in the Fish Islands off the coast of the Antarctic Peninsula. There is still much to learn about these places before we know better what those changes may be. See the special section beginning on page 588.
Photo: Pete McBride",A,MAC_Bench/Science/Cover/Science/387_6734.png,MAC_Bench/Science/Cover/Science/387_6734.png,groundtruth,387_6734.txt,MAC_Bench/Science/Cover/Science/350_6262.png,MAC_Bench/Science/Cover/Science/350_6262.png,ave_2,350_6262.txt,MAC_Bench/Science/Cover/Science/367_6484.png,MAC_Bench/Science/Cover/Science/367_6484.png,clip,367_6484.txt,MAC_Bench/Science/Cover/Science/379_6627.png,MAC_Bench/Science/Cover/Science/379_6627.png,ave_1,379_6627.txt,val
Cell Reports Physical Science,5_5,Which of the following options best describe the cover story?,"On the cover: Tsikriteas et al. present the development and comparison of various lead-free piezoelectric inks for
wearable technology. The printed systems exhibit excellent printability and strong
adhesion. The cover image highlights the integration of these systems into practical
real-world applications, showcasing their enhanced piezoelectric performance and advancements
towards more sustainable solutions in wearable tech. The cover design was created
by Ehsan Faridi.",D,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_1.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_1.png,vitg,1_1.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_12.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_12.png,clip,3_12.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_10.png,vith,3_10.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_5.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_5.png,groundtruth,5_5.txt,train
ACS Energy Letters,2025_1,Which of the following options best describe the cover story?,"The study investigates how substituted phosphonic acids influence the oxygen reduction reaction on Pt catalysts, revealing that, in addition to site blocking, these acids can also enhance reaction kinetics. These findings offer valuable insights for designing ionomer structures that optimize cathode reactions in high-temperature polymer electrolyte membrane fuel cells.",D,MAC_Bench/ACS/Cover/ACS Energy Letters/2019_8.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2019_8.png,vith,2019_8.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_11.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2021_11.png,ave_2,2021_11.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2018_1.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2018_1.png,clip,2018_1.txt,MAC_Bench/ACS/Cover/ACS Energy Letters/2025_1.png,MAC_Bench/ACS/Cover/ACS Energy Letters/2025_1.png,groundtruth,2025_1.txt,train
Trends in Pharmacological Sciences,45_11,Which of the following options best describe the cover story?,"Protein therapeutics are an important and growing class of medicines that tackle complex
diseases using multiple modes of action programmed into the protein sequence. In this
issue, Mock et al. discuss recent advances in the design
of protein therapeutics using generative biology, the seamless integration of modern
computational science with sophisticated laboratory technologies. In an era of great
excitement about artificial intelligence and machine learning, they focus on the most
promising technologies for practical implementation into biopharmaceutical drug discovery
pipelines. The cover illustration represents an iterative cycle of design-make-test-learn
to produce a bispecific antibody – a therapeutic protein capable of interacting with
two different targets in the body through two different binding domains, on the left
(cyan) and right (green). Cover image designed by Arie Opzeeland and Craig Kiefer
via Adobe Illustrator.",A,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_11.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_11.png,groundtruth,45_11.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/44_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/44_2.png,vitg,44_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/36_5.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/36_5.png,clip,36_5.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/44_13.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/44_13.png,vith,44_13.txt,val
Nature Cardiovascular Research,4_1,Which of the following options best describe the cover story?,"A mesenchymal progenitor for lymphatic endothelium
Lupu et al. demonstrate that mammalian lymphatic endothelial cells are specified directly from a population of specialized angioblasts, in a process that does not require transdifferentiation from venous endothelium.
See Lupu et al.
Image: Maria Diaz de la Loza, Scientific Illustrator. Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/4_1.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/4_1.png,groundtruth,4_1.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,vith,1_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_9.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_9.png,clip,3_9.txt,val
Molecular Therapy,32_6,Which of the following options best describe the cover story?,"On the cover:Smith et al. engineer novel immunoglobulin cleaving enzymes with the ability to target IgM, a
key trigger in the anti-AAV immune cascade. The image displays structural models of
the newly engineered enzyme (IceMG, blue and orange) docking onto and cleaving pentameric
IgM or monomeric IgG (gray) that are shown neutralizing an adeno-associated viral
(AAV) capsid (rainbow). Image credit: Timothy Smith, PhD.",C,MAC_Bench/Cell/Cover/Molecular Therapy/28_13.png,MAC_Bench/Cell/Cover/Molecular Therapy/28_13.png,clip,28_13.txt,MAC_Bench/Cell/Cover/Molecular Therapy/30_1.png,MAC_Bench/Cell/Cover/Molecular Therapy/30_1.png,vith,30_1.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_6.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_6.png,groundtruth,32_6.txt,MAC_Bench/Cell/Cover/Molecular Therapy/25_6.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_6.png,vitg,25_6.txt,train
Nature Neuroscience,27_4,Which of the following options best describe the cover story?,"A neural circuit for coughing
Coughing is a vital respiratory defense mechanism. Gannot et al. identified a genetically defined neural circuit connecting the airway to the brain that controls cough-like behavior in mice. The cover art features a mouse coughing, with a brain image illustrated in the droplets. The key brain region for coughing, the nucleus of the solitary tract, is highlighted in white.
See Peng Li et al.
Image: Rajani Arora, University of Michigan Life Sciences Institute. Cover design: Marina Spence",A,MAC_Bench/Nature/Cover/Nature Neuroscience/27_4.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_4.png,groundtruth,27_4.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/17_4.png,MAC_Bench/Nature/Cover/Nature Neuroscience/17_4.png,clip,17_4.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/12_5.png,MAC_Bench/Nature/Cover/Nature Neuroscience/12_5.png,ave_3,12_5.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/16_3.png,MAC_Bench/Nature/Cover/Nature Neuroscience/16_3.png,vitg,16_3.txt,train
Crystal Growth & Design,2024_14,Which of the following options best describe the cover story?,"Representation of the X-ray diffraction experiment for a truncated nanocube. The colors of the atom represent the zones with high (red) and low (blue) atomic vibration correlation in the nanocrystal. The white graph is the total scattering pattern, and the red line corresponds to the thermal diffuse scattering contribution to the pattern, where the information of atomic correlation is present.",B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2016_1.png,clip,2016_1.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_14.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2015_4.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2015_4.png,vith,2015_4.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_5.png,vitg,2024_5.txt,train
Science Immunology,9_96,Which of the following options best describe the cover story?,"ONLINE COVER γδ T Cells Across the Human Life Span. The functional role of human γδ T cells in tissues is poorly understood and has been largely limited to peripheral blood studies. Gray et al. characterized human γδ T cells in the blood and various mucosal and lymphoid tissues from nearly 200 donors ranging in age from a few days to over 80 years. Adult γδ T cell populations were highly differentiated and cytotoxic, whereas γδ T cells from infants and children were clonally diverse, tissue specific, and exhibited tissue repair functions and features of adaptive lymphocytes. This month’s cover depicts silhouettes of individuals at various stages of life nested within a stylized γδ T cell. Credit: Rich Thorne",C,MAC_Bench/Science/Cover/Science Immunology/2_7.png,MAC_Bench/Science/Cover/Science Immunology/2_7.png,vith,2_7.txt,MAC_Bench/Science/Cover/Science Immunology/3_29.png,MAC_Bench/Science/Cover/Science Immunology/3_29.png,clip,3_29.txt,MAC_Bench/Science/Cover/Science Immunology/9_96.png,MAC_Bench/Science/Cover/Science Immunology/9_96.png,groundtruth,9_96.txt,MAC_Bench/Science/Cover/Science Immunology/6_58.png,MAC_Bench/Science/Cover/Science Immunology/6_58.png,vitg,6_58.txt,train
Nature Photonics,19_2,Which of the following options best describe the cover story?,"Magneto-optic exceptional points
An artistic illustration of a highly sensitive magnetic field sensor that makes use of magneto-optic exceptional points. The apparatus consists of a Fabry–Perot cavity containing a magneto-optic crystal of terbium gallium garnet and a liquid-crystal cell. Frequency splitting of the modes at the exceptional point in the cavity provides a highly sensitive measurement of magnetic field strength.
See Ruan et al.
Image: Yanan Zhang, Senling (Shandong) Culture Transmission Co., LTD. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Photonics/19_1.png,MAC_Bench/Nature/Cover/Nature Photonics/19_1.png,vitg,19_1.txt,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,ave_2,16_12.txt,MAC_Bench/Nature/Cover/Nature Photonics/1_2.png,MAC_Bench/Nature/Cover/Nature Photonics/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Photonics/19_2.png,MAC_Bench/Nature/Cover/Nature Photonics/19_2.png,groundtruth,19_2.txt,test
Nature Chemical Biology,20_9,Which of the following options best describe the cover story?,"Putting the brakes on dynein
Cytoplasmic dynein is a motor complex that transports intracellular cargos toward the minus end of microtubules. The image depicts Lis1 binding to the dynein motor domain to facilitate the assembly of active dynein complexes, leading to a slower transport speed.
See Kusakci et al.
Image: Mert Golcuk, Istanbul Technical University; Mert Gur, Istanbul Technical University and University of Pittsburgh. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_2.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_2.png,vitg,18_2.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_6.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_6.png,vith,18_6.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_2.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_2.png,clip,15_2.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_9.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_9.png,groundtruth,20_9.txt,train
Accounts of Chemical Research,2024_1,Which of the following options best describe the cover story?,"In this Account, we summarize our ongoing research contributions, including (i) the design of flip-flop ligands and FDCs",C,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_4.png,vith,2024_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2014_2.png,clip,2014_2.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_1.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_22.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_22.png,vitg,2021_22.txt,train
Journal of Chemical Theory and Computation,2024_22,Which of the following options best describe the cover story?,"Solvent effects on the conformational dynamics and response to light excitation of multinuclear mixed valence metal complexes can be unveiled by mixed quantum classical approaches, based on molecular dynamics simulations carried out with quantum mechanically derived force-fields.",D,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_16.png,vitg,2023_16.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2015_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2015_5.png,vith,2015_5.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2017_10.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2017_10.png,clip,2017_10.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_22.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_22.png,groundtruth,2024_22.txt,train
Trends in Microbiology,32_4,Which of the following options best describe the cover story?,"Stressful environments provide unique ecological niches for microbial
evolution. The cover schematic depicts multiple strategies that bacteriophages
(phages) can adopt to cope with various physicochemical stressors, such as
extreme temperatures, radiation, and toxic pollutants. In this issue, Dan Huang and
colleagues review the impact of various environmental stressors on the physiological
state and community dynamics of phages and explore the adaptive strategies
employed by phages in response to these stressors. They also discuss the ecological
consequences of phage-host interactions within stressful environments. Image
courtesy: Dan Huang",D,MAC_Bench/Cell/Cover/Trends in Microbiology/32_11.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_11.png,vith,32_11.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/21_10.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_10.png,vitg,21_10.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/29_14.png,MAC_Bench/Cell/Cover/Trends in Microbiology/29_14.png,clip,29_14.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_4.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_4.png,groundtruth,32_4.txt,train
Nature Computational Science,4_4,Which of the following options best describe the cover story?,"Focus on DEI
This issue presents a Focus in which we explore the current state of diversity, equity, and inclusion (DEI) in computational science. The Focus features commentaries on representation and education, as well as insights on improving the design and application of computational tools to better serve various communities and to ensure fair and equitable practices.
See Focus and Editorial
Image: smartboy10 / DigitalVision Vectors / Getty Images. Cover design: Alex Wing",A,MAC_Bench/Nature/Cover/Nature Computational Science/4_4.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_4.png,groundtruth,4_4.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_5.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_5.png,clip,3_5.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_7.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_7.png,vitg,3_7.txt,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,vith,5_1.txt,train
Nature Cancer,6_1,Which of the following options best describe the cover story?,"Five years of Nature Cancer
We mark Nature Cancer’s fifth anniversary with a Series of specially commissioned Reviews and opinion pieces on key developments in cancer research and oncology, together with a collection of primary research articles published in Nature Cancer over the past 5 years.
See our January Editorial
Image: Lukas Jonaitis / Alamy Stock Photo. Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Cancer/2_2.png,MAC_Bench/Nature/Cover/Nature Cancer/2_2.png,ave_2,2_2.txt,MAC_Bench/Nature/Cover/Nature Cancer/6_1.png,MAC_Bench/Nature/Cover/Nature Cancer/6_1.png,groundtruth,6_1.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_2.png,MAC_Bench/Nature/Cover/Nature Cancer/4_2.png,vitg,4_2.txt,MAC_Bench/Nature/Cover/Nature Cancer/2_12.png,MAC_Bench/Nature/Cover/Nature Cancer/2_12.png,clip,2_12.txt,test
Journal of the American Chemical Society,2024_16,Which of the following options best describe the cover story?,"= 1 FeIII−(O22−)−CuII complex performs a H-bonding-mediated O−O bond cleavage in the presence of phenol, thereby providing insight into the prerequisites necessary for the efficient 4e/4H+ reduction of O2 to H2O in heme copper oxidases.",D,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2020_38.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2020_38.png,vith,2020_38.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_3.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_3.png,clip,2010_3.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,vitg,2010_30.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_16.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_16.png,groundtruth,2024_16.txt,train
Nature Reviews Cardiology,21_6,Which of the following options best describe the cover story?,"Immune checkpoints, inspired by the Review on p443.
Cover design: Vicky Summersby",B,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_2.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_2.png,clip,21_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_6.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_6.png,groundtruth,21_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/20_10.png,vitg,20_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_5.png,MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_5.png,vith,21_5.txt,train
Trends in Cognitive Sciences,29_1,Which of the following options best describe the cover story?,"Habits emerge from the interplay between two brain systems: a stimulus-response
(S–R) system that promotes the repetition of familiar actions, and a goal-directed
system that emphasizes flexibility and planning. Achieving the right balance between
these systems is essential, as disruptions can lead to action slips, impulsive behaviors,
or compulsions. In this issue of Trends in Cognitive Sciences, Eike K. Buabang and
colleagues explore how recent insights into these competing mechanisms can enhance
our ability to make and break habits. Building on these insights, they explore practical
applications for daily life and interventions for clinical populations affected by
imbalances
between these two systems. Cover art from Malte Mueller/Getty Images.",C,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/24_3.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/24_3.png,vitg,24_3.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/21_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/21_1.png,ave_0,21_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/29_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/29_1.png,groundtruth,29_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_10.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/18_10.png,clip,18_10.txt,test
Science Signaling,2007_384,Which of the following options best describe the cover story?,"COVER This week's Focus Issue contains an Editorial Guide on modulation of the immune response, as well as four Perspectives. The image depicts resolution of an inflammatory response. [Image: Christopher Bickel, AAAS]",C,MAC_Bench/Science/Cover/Science Signaling/6_258.png,MAC_Bench/Science/Cover/Science Signaling/6_258.png,vith,6_258.txt,MAC_Bench/Science/Cover/Science Signaling/2_78.png,MAC_Bench/Science/Cover/Science Signaling/2_78.png,vitg,2_78.txt,MAC_Bench/Science/Cover/Science Signaling/2007_384.png,MAC_Bench/Science/Cover/Science Signaling/2007_384.png,groundtruth,2007_384.txt,MAC_Bench/Science/Cover/Science Signaling/8_392.png,MAC_Bench/Science/Cover/Science Signaling/8_392.png,clip,8_392.txt,val
Current Biology,34_16,Which of the following options best describe the cover story?,"On the cover: A cushion of Saponaria sicula (Sicilian soapwort) and Cerastium tormentosum is growing in lava on Mount Etna in Sicily. Resilient, pioneer plants such as these
form the bedrock of ecosystem restoration approaches. The natural ecosystems on which
our survival and that of the biosphere depend are being destroyed by human activities
on a global scale—a crisis exacerbated by human-made climate change. Restoring functional
ecosystems is the objective of the UN Decade on Ecosystem Restoration and a worldwide
priority. Our special issue assembles reviews, essays, primers, and other formats
to showcase the scientific underpinnings of restoration and its implementation in
various biomes and with various objectives. Image by Florian Maderspacher.",B,MAC_Bench/Cell/Cover/Current Biology/21_16.png,MAC_Bench/Cell/Cover/Current Biology/21_16.png,clip,21_16.txt,MAC_Bench/Cell/Cover/Current Biology/34_16.png,MAC_Bench/Cell/Cover/Current Biology/34_16.png,groundtruth,34_16.txt,MAC_Bench/Cell/Cover/Current Biology/21_17.png,MAC_Bench/Cell/Cover/Current Biology/21_17.png,vith,21_17.txt,MAC_Bench/Cell/Cover/Current Biology/26_4.png,MAC_Bench/Cell/Cover/Current Biology/26_4.png,vitg,26_4.txt,train
Nature Photonics,18_9,Which of the following options best describe the cover story?,"Perovskite polaritons
Artistic image of the polariton spin Hall effect in a liquid-crystal-filled perovskite microcavity under electrical voltages at room temperature. The findings represent a development in the generation and manipulation of pure polariton spins for spin-optoelectronic applications.
See Liang et al.
Image: Rui Su, Nanyang Technological University, Singapore. Cover Design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,MAC_Bench/Nature/Cover/Nature Photonics/16_12.png,clip,16_12.txt,MAC_Bench/Nature/Cover/Nature Photonics/14_4.png,MAC_Bench/Nature/Cover/Nature Photonics/14_4.png,vith,14_4.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_9.png,MAC_Bench/Nature/Cover/Nature Photonics/18_9.png,groundtruth,18_9.txt,MAC_Bench/Nature/Cover/Nature Photonics/15_3.png,MAC_Bench/Nature/Cover/Nature Photonics/15_3.png,ave_0,15_3.txt,val
ACS Agricultural Science & Technology,2024_4,Which of the following options best describe the cover story?,"Non-covalent interactions between pesticides and carriers in pesticide controlled-release systems significantly impact the system's stability, stimulus responsiveness, loading capacity, and physicochemical properties of pesticides, such as hydrogen-bonding interactions, electrostatic interactions, hydrophobic interactions, and supramolecular host–guest interactions. Modifying multiple assembly sites on carriers or combining various carriers to construct a new type of pesticide controlled-release system with multiple non-covalent bond interactions can play a more significant role in the development of green agriculture.",C,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_5.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_5.png,clip,2023_5.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_1.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_1.png,ave_3,2023_1.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_4.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_3.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_3.png,vitg,2023_3.txt,val
NATURE REVIEWS DRUG DISCOVERY,23_6,Which of the following options best describe the cover story?,"Sequential immunotherapy, inspired by the Review on p501.
Cover design: S. Harris",B,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_6.png,vith,21_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_6.png,groundtruth,23_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_10.png,clip,22_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_5.png,vitg,22_5.txt,val
Chemistry of Materials,2025_3,Which of the following options best describe the cover story?,"The cover art visually captures the fusion of nanomaterials with mitochondria targeting, imaging, and image-guided treatment. The mitochondria are targeted by floating molecules, such as rhodamine and",D,MAC_Bench/ACS/Cover/Chemistry of Materials/2018_24.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2018_24.png,vith,2018_24.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2015_15.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2015_15.png,clip,2015_15.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2017_11.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2017_11.png,ave_1,2017_11.txt,MAC_Bench/ACS/Cover/Chemistry of Materials/2025_3.png,MAC_Bench/ACS/Cover/Chemistry of Materials/2025_3.png,groundtruth,2025_3.txt,train
Med,6_2,Which of the following options best describe the cover story?,"On the cover: Immunotherapy has revolutionized the standards of care for individuals
with cancer, yet not all patients obtain long-lasting benefit from these therapies.
This month, we feature a special issue covering the latest developments in cancer
immunotherapeutics, ranging from cell-based therapies to vaccines and tumor-targeting
bacteria. Through a series of Q&As, reviews and opinion pieces, we seek to highlight
some existing challenges in this field as well as potential breakthroughs that may
improve efficacy and deliver on the clinical promise of immunotherapy. Cover image:
Isaac Lane Koval/Corbis/VCG via Getty Images.",B,MAC_Bench/Cell/Cover/Med/4_7.png,MAC_Bench/Cell/Cover/Med/4_7.png,vitg,4_7.txt,MAC_Bench/Cell/Cover/Med/6_2.png,MAC_Bench/Cell/Cover/Med/6_2.png,groundtruth,6_2.txt,MAC_Bench/Cell/Cover/Med/5_9.png,MAC_Bench/Cell/Cover/Med/5_9.png,clip,5_9.txt,MAC_Bench/Cell/Cover/Med/4_6.png,MAC_Bench/Cell/Cover/Med/4_6.png,ave_1,4_6.txt,test
ACS Synthetic Biology,2024_4,Which of the following options best describe the cover story?,"Creation of a “superhero” Corynebacterium glutamicum strain through systems metabolic engineering techniques, resulting in the ability to produce L-valine with high titer and yield by utilizing glucose and ammonia as the primary carbon and nitrogen sources.",D,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,clip,2024_6.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2016_8.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2016_8.png,vitg,2016_8.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_5.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_5.png,ave_1,2024_5.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_4.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_4.png,groundtruth,2024_4.txt,test
The Journal of Physical Chemistry Letters,2025_6,Which of the following options best describe the cover story?,"The illustration shows the ion and charge migration in a perovskite solar cell under reverse electrical bias highlighting the interplay of different species in different layers and interfaces. Using spatially resolved scanning transmission X-ray microscopy and electrochemical impedance spectroscopy, the mechanisms behind these migrations are explored,",B,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_43.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_43.png,vith,2021_43.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_6.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2024_44.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2024_44.png,vitg,2024_44.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2017_7.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2017_7.png,clip,2017_7.txt,train